HAMANOUE Makoto 浜之上誠

… Alternative Names

浜之上誠ハマノウエマコト

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Researcher Number	00312025
Other IDs
Affiliation (based on the past Project Information) *help	2010 – 2014: 東邦大学, 医学部, 講師 2012: 東邦大学, 医学部・医学科・生理学講座, 講師 2007: 東邦大学, 医学部, 助教 2001 – 2006: 東邦大学, 医学部, 助手 2000: 東京慈恵会医科大学, DNA研究所・分子神経部門, 助手
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology Except Principal Investigator Neurochemistry/Neuropharmacology / Rehabilitation science/Welfare engineering / Cerebral neurosurgery
Keywords	Principal Investigator p38 MAPキナーゼ / オリゴデンドロサイト / アポトーシス / NF-κB / 神経幹細胞 / 培養系 / 細胞移動 / Tat融合蛋白質 / プロテインキナーゼ / 細胞遊走 … More / 内在性神経幹細胞 / 損傷脳 / 細胞遊走活性 / りん酸化酵素 / 膜透過型蛋白質 / JNK / NF-kappaB / 転写因子 / アポトーシス阻害 / カスパーゼ / 神経細胞 … More Except Principal Investigator TAT / HIV / p38MAPキナーゼ / Apoptosis / p38MAP kinase / Oligodendrocyte / アポトーシス / オリゴデンドロサイト / 筋電図測定 / 歩行運動解析 / 歩行運動 / ミクログリア / 痙縮 / 歩行機能 / 脊髄損傷 / リハビリテーション / p38 MAP kinase / tatペプチド / 細胞増殖 / 細胞分裂 / 神経幹細胞 Less

Manufacturing neural circuit in chronic spinal cord injury models
- Principal Investigator
  
  AKAI Masami
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  National Rehabilitation Center for Persons with Disabilities
Functional analysis of the activatingfactor for endogenous neural stem cell migraion to develop the regeneration therapy for the injured brain.Principal Investigator
- Principal Investigator
  
  HAMANOUE Makoto
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Toho University
p38MAPキナーゼ阻害剤による神経幹細胞生着率改善効果の検討
- Principal Investigator
  
  青木和哉
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Toho University
Regulation of the survival of mature oligodendrocytes by protein transduction of p38 MAP kinase
- Principal Investigator
  
  TAKAMATSU Ken
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Toho University
転写因子による神経系細胞アポトーシス阻害機構の解析Principal Investigator
- Principal Investigator
  
  浜之上誠
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Toho University
組み換えNF-κBウィルスを用いた神経細胞アポトーシス阻害活性の解析Principal Investigator
- Principal Investigator
  
  浜之上誠
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Toho University
  Jikei University School of Medicine

All 2013 2012 2011 2010 2007 2004 Other

All Journal Article Presentation

[Journal Article] Hippocalcin mediates calcium-dependent translocation of brain-type creatine kinase (BB-CK) in hippocampal neurons2012
- Author(s)
  Kobayashi M, Hamanoue M, Masaki T, Furuta Y, Takamatsu K
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 429
- URL
  http://dx.doi.org/10.1016/j.bbrc.2012.10.125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500340
[Journal Article] Hippocalcin mediates calcium-dependent translocation of brain-type creatine kinase (BB-CK) in hippocampal neurons2012
- Author(s)
  Masaaki Kobayashi, Makoto Hamanoue, Tamotsu Masaki, Yoshitaka Furuta, Ken Takamatsu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 3-4 Issue: 3-4 Pages: 142-147
- DOI
  10.1016/j.bbrc.2012.10.125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500340, KAKENHI-PROJECT-22500341
[Journal Article] Schwann Cell Plasticity After Spinal Cord Injury Shown by Neural Crest Lineage Tracing2011
- Author(s)
  Nagoshi N, Shibata S, Hamanoue M, Mabuchi Y, Matsuzaki Y, Toyama Y, Nakamura M, Okano H
- Journal Title
  
  Glia
  
  Volume: 59 Pages: 771-784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500340
[Journal Article] Cell surface N-glycans mediated isolation of mouse neural stem cells2011
- Author(s)
  Hamanoue M, Okano H
- Journal Title
  
  J Cell Physiology
  
  Volume: 226,6 Issue: 6 Pages: 1433-1438
- DOI
  10.1002/jcp.22436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500340
[Journal Article] Schwann Cell Plasticity After Spinal Cord Injury Shown by Neural Crest Lineage Tracing2011
- Author(s)
  Nagoshi N, Shibata S, Hamanoue M, et al.
- Journal Title
  
  GLIA
  
  Volume: 59 Pages: 771-784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500340
[Journal Article] Inhibition of p38 mitogen-activated protein kinase-induced apoptosis in cultured mature oligodendrocytes using SB203580.2007
- Author(s)
  Hamanoue M
- Journal Title
  
  Neurochem Int (In press)
- Data Source
  KAKENHI-PROJECT-17500262
[Journal Article] Inhibition of p38 mitogen-activated protein kinase-induced apoptosis in cultured mature oligodendrocytes using SB202190 and SB203580.2007
- Author(s)
  Hamanoue M, et al.
- Journal Title
  
  Neurochem Int (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500262
[Journal Article] Inhibition of p38 mitogen-activated protein kinase-induced apoptosis in cultured mature oligodendrocytes using SB202190 and SB203580.2007
- Author(s)
  Hamanoue M
- Journal Title
  
  Neurochem Int (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500262
[Journal Article] Inhibition of p38 mitogen-activated protein kinase-induced apoptosis in cultured mature oligodendrocytes using SB202190 and SB203580.2007
- Author(s)
  Hamanoue M
- Journal Title
  
  Neurochem Int (In press)
- Data Source
  KAKENHI-PROJECT-18659428
[Journal Article] NF-κB prevents TNF-α-induced apoptosis in an oligodendrocyte cell line2004
- Author(s)
  Makoto Hamanoue et al.
- Journal Title
  
  Neurochemical Research 29・8
  
  Pages: 1571-1576
- Data Source
  KAKENHI-PROJECT-14780583
[Presentation] 神経幹細胞に特異的に発現する糖転移酵素2013
- Author(s)
  浜之上誠, 池田義孝, 高松研
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] p38 MAP kinase enhances secretion of GDNF and VEGF from rat spinal cord microglia. The 11th Biennial Meeting of the Asian Pacific Society for Neurochemistry, The 55th Annual Meeting of the Japanese Society for Neurochemistry2012
- Author(s)
  Hamanoue M, Morioka K, Ogata T, Nakajima K, Takamatsu K
- Organizer
  The34th Annual Meeting of Japanese Society of Biological Phychiatry
- Place of Presentation
  Kobe International Conference Center
- Year and Date
  2012-09-30
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] 細胞外キナーゼによるミクログリア活性化機構の解析2012
- Author(s)
  浜之上誠, 中嶋一行, 高松研
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] 慢性脊髄損傷に対する内在性ミクログリア活性化療法の基礎的研究2012
- Author(s)
  浜之上誠, 森岡和仁, 緒方徹, 中嶋一行, 高松研
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] Secretion of growth factors from spinal cord microglia are enhanced by p38 MAP kinase2012
- Author(s)
  Hamanoue M, Morioka K, Ogata T, Nakajima K, Takamatsu K
- Organizer
  Secretion of growth factors from spinal cord microglia are enhanced by p38 MAP kinase
- Place of Presentation
  New Orleans, USA
- Year and Date
  2012-10-15
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] 内在性神経幹細胞遊走能活性化分子の機能解析2012
- Author(s)
  浜之上誠, 原科純一
- Organizer
  第139回東邦医学会例会
- Place of Presentation
  東京
- Year and Date
  2012-02-10
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] Erk2 regulates proinflammatory gene expressions in demyelinating disorders.Neuroscience 20122012
- Author(s)
  Okazaki R, Hayakawa K, Morioka K, Imamura O, Takishima K, Hamanoue M, Endo S, Tanaka S, Ogata T
- Organizer
  the 42th Annual SfN Meeting Neuroscience
- Place of Presentation
  New Orleans
- Year and Date
  2012-10-17
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] Binding profile and intracellular colocalization between hippocalcin and creatine kinase B subunit. The 11th Biennial Meeting of the Asian Pacific Society for Neurochemistry2012
- Author(s)
  Kobayashi M, Hamanoue M, Takamatsu K
- Organizer
  The 55th Annual Meeting of the Japanese Society for Neurochemistry, The34th Annual Meeting of Japanese Society of Biological Phychiatry
- Place of Presentation
  Kobe International Conference Center
- Year and Date
  2012-10-01
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] 細胞外キナーゼによるミクログリア活性化機構の解析2012
- Author(s)
  浜之上誠、中嶋一行、高松研
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本文化会館(松本)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] ヒポカルシンと脳型クレアチンキナーゼ(CKB)の結合特性2011
- Author(s)
  小林正明, 浜之上誠, 高松研
- Organizer
  第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  横浜
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] 神経幹細胞内在性遊走能活性化分子の機能解析2011
- Author(s)
  浜之上誠、水野隆明、岡野洋尚、芝田晋介、岡野栄之、高松研
- Organizer
  第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  (誌上開催)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] 神経幹細胞における糖転移酵素の発現と機能解析. Neuroscience20112011
- Author(s)
  浜之上誠, 池田義孝, 高松研
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] The roles of n-acetylglucosaminyltransferase in adult mouse neural stem cells.Neuroscience 20112011
- Author(s)
  Hamanoue M, Ikeda Y, Takamatsu K
- Organizer
  the 41th Annual SfN Meeting Neuroscience
- Place of Presentation
  Washington DC, USA
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] HIV-Tat-p38MAPキナーゼ蛋白質による神経幹細胞増殖誘導機構の解析2011
- Author(s)
  浜之上誠, 佐藤健一郎
- Organizer
  第137回東邦医学会例会
- Place of Presentation
  東京
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] 神経幹細胞内在性遊走能活性化分子の機能解析2011
- Author(s)
  浜之上誠, 水野隆明, 岡野ジェイムス洋尚, 芝田晋介, 岡野栄之, 高松研
- Organizer
  第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  横浜
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] 神経幹細胞における糖転移酵素の発現と機能解析2011
- Author(s)
  浜之上誠、池田義隆、高松研
- Organizer
  Neuroscience2011,第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] The roles of n-acetylglucosaminyltransferase in adult mouse neural stem cells2011
- Author(s)
  Hamanoue M, Ikeda Y, Takamatsu K
- Organizer
  Neuroscience 2011, the 41th Annual SfN Meeting Neuroscience
- Place of Presentation
  Washington DC, USA
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] TAT-p38 MAPKタンパク質導入による神経幹細胞遊走能亢進作用2010
- Author(s)
  浜之上誠、水野隆明、高松研
- Organizer
  第87回日本生理学大会
- Place of Presentation
  盛岡市民文化ホール(岩手県)
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] ヒポカルシンを介した脳型クレアチンキナーゼのカルシウム依存性トランスロケーション2010
- Author(s)
  小林正明、浜之上誠、高松研
- Organizer
  第87回日本生理学大会
- Place of Presentation
  盛岡市民文化ホール(岩手県)
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] 糖尿病性腎症における腎ACE/ACE2、Ang1-7、Mas receptor2010
- Author(s)
  水入苑生, 浜之上誠, 篠崎稔, 酒井謙, 大橋靖, 青木敏行, 河村毅, 渋谷和俊, 相川厚
- Organizer
  第53回日本腎臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] Protein transduction of Tat-p38 MAP kinase enhances adult neural progenitor cell migration. Neuroscience 20102010
- Author(s)
  Hamanoue M, Okano HJ, Mizuno T, Shibata S, Okano H, Takamatsu K
- Organizer
  the 40th Annual SfN Meeting Neuroscience
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] p38MAPキナーゼ直接導入による神経幹細胞遊走能活性化の解析2010
- Author(s)
  浜之上誠, 水野隆明, 岡野ジェイムス洋尚、岡野栄之, 高松研
- Organizer
  Neuro2010,第33回日本神経科学大会、第53回日本神経化学会大会、第20回日本神経回路学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] TAT-p38 MAPKタンパク質導入による神経幹細胞遊走能亢進作用2010
- Author(s)
  浜之上誠, 水野隆明, 高松研
- Organizer
  第87回日本生理学大会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] 脳型クレアチンキナーゼのカルシウム/ヒポカルシン依存性トランスロケーション2010
- Author(s)
  小林正明, 浜之上誠, 高松研
- Organizer
  Neuro2010,第33回日本神経科学大会、第53回日本神経化学会大会、第20回日本神経回路学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] ACE/ACE2-Angiotensin (1-7)-MAS Receptor Expression in Diabetic Nephropathy2010
- Author(s)
  Mizuiri1 S, Hamanoue M, Hemmi H, Arita M, Aoki T, Ohashi Y, Sakai K, Shinozaki M, Shibuya K, Aikawa A
- Organizer
  ASN's 43rd Annual Meeting and Scientific Exposition
- Place of Presentation
  Denver, USA
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] ヒポカルシンを介した脳型クレアチンキナーゼのカルシウム依存性トランスロケーション2010
- Author(s)
  小林正明, 浜之上誠, 高松研
- Organizer
  第87回日本生理学大会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] p38MAPキナーゼ直接導入による神経幹細胞遊走能活性化の解析2010
- Author(s)
  浜之上誠、水野隆明、岡野洋尚、岡野栄之、高松研
- Organizer
  Neuro2010,第33回日本神経科学大会、第53回日本神経化学会大会、第20回日本神経回路学会大会
- Place of Presentation
  神戸コンベンションセンター(兵庫県)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] マウス神経幹細胞生存・増殖機構におけるp38 MAP kinaseの役割2007
- Author(s)
  浜之上誠
- Organizer
  第30回日本神経科学大会第50回日本神経化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18659428
[Presentation] Secretion of growth factors from spinal cord microglia are enhanced by p38 MAP kinase.
- Author(s)
  Makoto Hamanoue, Kazuhito Morioka, Toru Ogata, Kazuyuki Nakajima, Ken Takamatsu
- Organizer
  Neuroscience 2012, the 42th Annual SfN Meeting Neuroscience
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] 神経幹細胞に特異的に発現する糖転移酵素GnT-V
- Author(s)
  浜之上　誠、池田　義孝、高松　研
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀(東京都)
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] Erk2 regulates proinflammatory gene expressions in demyelinating disorders
- Author(s)
  R OKAZAKI, K. HAYAKAWA, K. MORIOKA, O. IMAMURA, K. TAKISHIMA, M. HAMANOUE, S. ENDO, S. TANAKA, T. OGATA
- Organizer
  Neuroscience 2012, the 42th Annual SfN Meeting Neuroscience
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] p38 MAP kinase enhances secretion of GDNF and VEGF from rat spinal cord microglia.
- Author(s)
  Makoto Hamanoue, Kazuhito Morioka, Toru Ogata, Kazuyuki Nakajima, Ken Takamatsu
- Organizer
  The 11th Biennial Meeting of the Asian Pacific Society for Neurochemistry
- Place of Presentation
  Kobe International Conference Center(Kobe,Japan)
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] 慢性脊髄損傷に対する内在性ミクログリア活性化療法の基礎的研究
- Author(s)
  浜之上　誠、森岡　和仁、緒方　徹、中嶋　一行、高松　研
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県)
- Data Source
  KAKENHI-PROJECT-22500340
[Presentation] Binding profile and intracellular colocalization between hippocalcin and creatine kinase B subunit.
- Author(s)
  Masaaki Kobayashi, Makoto Hamanoue, Ken Takamatsu
- Organizer
  The 11th Biennial Meeting of the Asian Pacific Society for Neurochemistry
- Place of Presentation
  Kobe International Conference Center(Kobe,Japan)
- Data Source
  KAKENHI-PROJECT-22500340

1. 青木和哉 (50202461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. AKAI Masami (80143452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. OGATA Toru (00392192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKAMATSU Ken (90154898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OSAWA Ikrou (30343586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HAMANOUE Makoto 浜之上 誠

浜之上 誠 ハマノウエ マコト

Research Projects

Research Products

Co-Researchers

Manufacturing neural circuit in chronic spinal cord injury models

Principal Investigator

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Functional analysis of the activatingfactor for endogenous neural stem cell migraion to develop the regeneration therapy for the injured brain.Principal Investigator

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p38MAPキナーゼ阻害剤による神経幹細胞生着率改善効果の検討

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Regulation of the survival of mature oligodendrocytes by protein transduction of p38 MAP kinase

Principal Investigator

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Research Institution

転写因子による神経系細胞アポトーシス阻害機構の解析Principal Investigator

Principal Investigator

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組み換えNF-κBウィルスを用いた神経細胞アポトーシス阻害活性の解析Principal Investigator

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[Journal Article] Hippocalcin mediates calcium-dependent translocation of brain-type creatine kinase (BB-CK) in hippocampal neurons2012

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[Journal Article] Hippocalcin mediates calcium-dependent translocation of brain-type creatine kinase (BB-CK) in hippocampal neurons2012

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[Journal Article] Schwann Cell Plasticity After Spinal Cord Injury Shown by Neural Crest Lineage Tracing2011

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[Journal Article] Cell surface N-glycans mediated isolation of mouse neural stem cells2011

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[Journal Article] Schwann Cell Plasticity After Spinal Cord Injury Shown by Neural Crest Lineage Tracing2011

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[Journal Article] Inhibition of p38 mitogen-activated protein kinase-induced apoptosis in cultured mature oligodendrocytes using SB203580.2007

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[Journal Article] Inhibition of p38 mitogen-activated protein kinase-induced apoptosis in cultured mature oligodendrocytes using SB202190 and SB203580.2007

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[Journal Article] Inhibition of p38 mitogen-activated protein kinase-induced apoptosis in cultured mature oligodendrocytes using SB202190 and SB203580.2007

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[Journal Article] Inhibition of p38 mitogen-activated protein kinase-induced apoptosis in cultured mature oligodendrocytes using SB202190 and SB203580.2007

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HAMANOUE Makoto 浜之上誠

浜之上誠ハマノウエマコト