Kohno Tatsuro 河野達郎

… Alternative Names

KOHNO Tatsuro 河野達郎

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Researcher Number	00313536
Other IDs
Affiliation (Current)	2025: 千葉大学, 医学部附属病院, 特任教授
Affiliation (based on the past Project Information) *help	2025: 千葉大学, 医学部附属病院, 特任教授 2020 – 2023: 国際医療福祉大学, 国際医療福祉大学成田病院, 教授 2016 – 2019: 東北医科薬科大学, 医学部, 教授 2008 – 2016: Niigata University, 医歯学系, 准教授 2006: Niigata University, Institute of Medicine and Dentistry, Associate Professor, 医歯学系, 助教授 2004 – 2005: 新潟大学, 医歯学総合病院, 助手
Review Section/Research Field	Principal Investigator Anesthesiology / Basic Section 55050:Anesthesiology-related / Anesthesiology/Resuscitation studies Except Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology
Keywords	Principal Investigator 脊髄後角 / 脊髄 / 下行性疼痛調節系 / 脳―脊髄連関 / 下行性疼痛抑制系 / 鎮痛機序 / 脊髄前角ニューロン / アセトアミノフェン / 疼痛 / オピオイド … More / 痛覚過敏 / 急性耐性 / μオピオイド / 大脳体性感覚野 / フラビン蛋白蛍光イメージング / 大脳体性感覚 / フラビン蛍光蛋白 / しびれ / タニケットペイン / 不動化 / 鎮痛 / 麻酔薬 … More Except Principal Investigator パッチクランプ / 脊髄後角 / 脊髄損傷 / 脊髄 / エダラボン / NMDA受容体 / 痛み / リドカイン / synaptic transmission / GABA / dorsal horn / inhaled anesthetics / シナプス伝達 / ガンマアミノ酪酸 / 吸入麻酔薬 / 脊髄前角運動ニューロン / 麻酔 / 神経保護 / 脊髄前角ニューロン / 麻酔薬 / 副腎皮質ステロイド / 疼痛 / ステロイド / NMDA受容体拮抗薬 / 耐性 / 痛覚過敏 / 急性耐性 / レミフェンタニル / 運動誘発電位 / 脊髄機能モニタリング / 損傷 / Glycine受容体 / MAPK / アストロサイト / ブラインドパッチクランプ法 / グリシントランスポーター / 神経障害性疼痛 / グリア由来伝達物質 / D-serine / グリシン受容体 / グリア細胞 / spare nerve injury mode / 疼痛管理学 / 総頸動脈遮断 / 欠損マウス / 脳保護 Less

交番磁界治療器(エイト)の鎮痛機序の解明Principal Investigator
- Principal Investigator
  
  河野達郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Chiba University
The elucidation of the brain-spinal cord interactions involved in descending pain modulationPrincipal Investigator
- Principal Investigator
  
  KOHNO Tatsuro
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  International University of Health and Welfare
  Tohoku Medical and Pharmaceutical University
Free radical scavenger edaravone produces robust neuroprotection in a rat model of spinal cord injury
- Principal Investigator
  
  ISHII Hideaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Niigata University
Analgesic mechanism of lidocaine metabolite, and the potential as an analgesic drug
- Principal Investigator
  
  Furutani Kenta
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Niigata University
Elucidation of the underlying mechanism of acetaminophen in the brain and spinal cordPrincipal Investigator
- Principal Investigator
  
  Tatsuro Kohno
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology
- Research Institution
  Niigata University
Underlynig intracellular signal mechanism of acute tolerance and huperalgesia induced by mu opioidsPrincipal Investigator
- Principal Investigator
  
  KOHNO Tatsuro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology
- Research Institution
  Tohoku Medical and Pharmaceutical University
  Niigata University
Effects and neuroprotection of the anesthetic agent in the spinal ventral horn neuron
- Principal Investigator
  
  HONDA Hiroyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Niigata University
Elucidation of mechanism of tourniquet painPrincipal Investigator
- Principal Investigator
  
  KOHNO Tatsuro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology
- Research Institution
  Niigata University
Acute analgesic tolerance during and hyperalgesia after prolonged remifentanil administration in mice
- Principal Investigator
  
  ISHII Hideaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Niigata University
Non-genomic antinociceptive effects of glucocorticoids on rat spinal cord
- Principal Investigator
  
  IKOMA miho
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Niigata University
Edaravone exhibits neuroprotective effects in rats following acute spinal cord injury
- Principal Investigator
  
  TOBITA Toshiyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Niigata University
A role of glycine transporter on spinal dorsal horn neuron through the pain sensation produced by neuropathic pain model
- Principal Investigator
  
  KAWASAKI Yasuhiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kansai University of Health Sciences
  Niigata University
Analysis of inhaled anesthetics on the analgesic effect and immobilization in the spinal cordPrincipal Investigator
- Principal Investigator
  
  KOHNO Tatsuro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Niigata University
虚血条件付けの脳保護機序におけるNMDA受容体εサブユニット分子種の役割
- Principal Investigator
  
  山倉智宏
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Niigata University
Action of inhaled anesthetics on spinal dorsal horn neurons
- Principal Investigator
  
  SHIBUE Chieko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Niigata University

All 2018 2017 2013 2012 2011 2010 2009 2006 Other

All Journal Article Presentation Book

[Book] Brain Medical2009
- Author(s)
  川崎康彦、河野達郎
- Data Source
  KAKENHI-PROJECT-21592015
[Journal Article] Free radical scavenger edaravone produces robust neuroprotection in a rat model of spinal cord injury2018
- Author(s)
  Ishii Hideaki、Petrenko Andrey B.、Sasaki Mika、Satoh Yukio、Kamiya Yoshinori、Tobita Toshiyuki、Furutani Kenta、Matsuhashi Mari、Kohno Tatsuro、Baba Hiroshi
- Journal Title
  
  Brain Research
  
  Volume: 1682 Pages: 24-35
- DOI
  10.1016/j.brainres.2017.12.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10505
[Journal Article] Acetaminophen metabolite AM404 induces analgesia via TRPV1 receptors expressed on the primary afferent terminals of C-fibers in the spinal dorsal horn2017
- Author(s)
  Nobuko Ohashi, Daisuke Uta, Mika Sasaki, Masayuki Ohashi, Yoshinori Kamiya, Tatsuro Kohno
- Journal Title
  
  Anesthesiology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15566
[Journal Article] 脊髄機能モニタリングと麻酔管理2012
- Author(s)
  石井秀明、飛田俊幸、河野達郎、馬場洋
- Journal Title
  
  臨床麻酔
  
  Volume: (36) Pages: 1294-1303
- Data Source
  KAKENHI-PROJECT-23592278
[Journal Article] 脊髄機能モニタリングと麻酔管理2012
- Author(s)
  石井秀明　飛田俊幸　河野達郎　馬場洋
- Journal Title
  
  臨床麻酔
  
  Volume: 36 Pages: 1294-1303
- Data Source
  KAKENHI-PROJECT-23592278
[Journal Article] キセノンの脊髄後角における興奮性・抑制性シナプス伝達に対する作用2011
- Author(s)
  ゲオルギエフステファン、古江秀昌、河野達郎
- Journal Title
  
  脊髄機能診断学 32巻
  
  Pages: 214-216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390414
[Journal Article] Zaltoprofen inhibits bradykinin-mediated enhancement of glutamate receptor activity in substantia getatinosa neurons2011
- Author(s)
  Kohno T
- Journal Title
  
  Anesth Analg
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390414
[Journal Article] Effect of d-serine on spinal dorsal horn neurons2011
- Author(s)
  Kawasaki Y, Nakatsuka T, Sasaki M, Amaya F, Kohno T
- Journal Title
  
  Pain res
  
  Volume: 26 Pages: 19-28
- Data Source
  KAKENHI-PROJECT-21592015
[Journal Article] 脊髄における全身麻酔薬の作用機序2011
- Author(s)
  山本知裕、本田博之、河野達郎
- Journal Title
  
  麻酔 60
  
  Pages: 582-589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390414
[Journal Article] Nitrous oxide and the inhibitory synaptic transmission in rat dorsal horn neurons2010
- Author(s)
  Stefan K Georgiev、Hiroshi Baba、Tatsuro Kohno
- Journal Title
  
  European Journal of Pain 14
  
  Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390414
[Journal Article] Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons2010
- Author(s)
  Stefan K Georgiev、Hidemasa Furue、Hiroshi Baba、Tatsuro Kohno
- Journal Title
  
  Molecular Pain 6
  
  Pages: 25-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390414
[Journal Article] 亜酸化窒素の脊髄後角II層における抑制性シナプス伝達に対する作用2010
- Author(s)
  ゲオルギエフ・ステファン、馬場洋、河野達郎
- Journal Title
  
  脊髄機能診断学 33巻
  
  Pages: 12-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390414
[Journal Article] 脊髄における下行性抑制系の役割2009
- Author(s)
  川崎康彦、河野達郎
- Journal Title
  
  Brain Medical 21
  
  Pages: 251-256
- Data Source
  KAKENHI-PROJECT-21592015
[Journal Article] Actions of midazolam on excitatory transmission in dorsal horn neurons.2006
- Author(s)
  Kohno T
- Journal Title
  
  Anesthesiology 104
  
  Pages: 338-343
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591529
[Journal Article] Actions of midazolam on excitatory transmission in dorsal horn neurons of adul t rat spinal cord.2006
- Author(s)
  Kohno T
- Journal Title
  
  Anesthesiology 104
  
  Pages: 338-343
- Data Source
  KAKENHI-PROJECT-16591529
[Journal Article] Actions of midazolam on excitatory transmission in dorsal horn neurons of adult rat spinal cord.2006
- Author(s)
  Kohno T
- Journal Title
  
  Anesthesiology 104
  
  Pages: 338-343
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591529
[Presentation] アセトアミノフェンは脊髄レベルで鎮痛効果を発揮する2017
- Author(s)
  河野達郎
- Organizer
  第39回日本疼痛学会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2017-06-16
- Data Source
  KAKENHI-PROJECT-15K15566
[Presentation] ラットの脊髄運動誘発電位によるエダラボンの神経保護作用の検討2013
- Author(s)
  石井秀明、飛田俊幸、河野達郎、馬場洋
- Organizer
  日本麻酔科学会第60回学術集会
- Place of Presentation
  札幌市
- Year and Date
  2013-05-24
- Data Source
  KAKENHI-PROJECT-23592278
[Presentation] 脊髄運動ニューロンのシナプス伝達に対するキセノンの作用2011
- Author(s)
  山本知裕、本田博之、河野達郎
- Organizer
  第58回日本麻酔科学会学術集会
- Place of Presentation
  兵庫県
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-20390414
[Presentation] キセノンの脊髄後角における興奮性・抑制性シナプス伝達に対する作用2010
- Author(s)
  ゲオルギエフステファン、古江秀昌、河野達郎
- Organizer
  第32回脊髄機能診断研究会
- Place of Presentation
  東京都
- Year and Date
  2010-02-06
- Data Source
  KAKENHI-PROJECT-20390414
[Presentation] キセノンの脊髄後角における興奮性・抑制性シナプス伝達に対する作用2010
- Author(s)
  河野達郎、ゲオルギエフステファン
- Organizer
  第57回日本麻酔科学会学術集会
- Place of Presentation
  福岡県
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-20390414
[Presentation] Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons2010
- Author(s)
  Stefan K Georgiev、Tatsuro Kohno、Tatsuro Kohno
- Organizer
  40^<th> Annual meeting of neuroscience
- Place of Presentation
  San Diego(CA,USA)
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-20390414
[Presentation] キセノンの脊髄後角における興奮性・抑制性シナプス伝達に対する作用2010
- Author(s)
  河野達郎, 他1名
- Organizer
  日本麻酔科学会第57回学術集会
- Place of Presentation
  福岡
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-20390414
[Presentation] 亜酸化窒素の脊髄第II層における抑制性シナプス伝達に対する作用2009
- Author(s)
  ゲオルギエフステファン、河野達郎
- Organizer
  第31回脊髄機能診断研究会
- Place of Presentation
  東京都
- Year and Date
  2009-02-07
- Data Source
  KAKENHI-PROJECT-20390414
[Presentation] 神経ステロイドDHEASはラット脊髄後角においてシグマ1受容体とNMDA受容体を介して痛覚増強作用を発揮する
- Author(s)
  山本豪，生駒美穂，紙谷義孝，馬場洋，河野達郎
- Organizer
  麻酔科学会
- Place of Presentation
  神戸ポートビアホテル
- Year and Date
  2015-05-28 – 2015-05-30
- Data Source
  KAKENHI-PROJECT-24592330

1. IKOMA Miho (30432082)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. ISHII Hideaki (60529775)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. TERUMASA Nakatsuka (30380752)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. SHIBUKI Katsuei (40146163)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KAWASAKI Yasuhiko (50535755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. TOBITA Toshiyuki (80262442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. ANDREY B Petrenko (30397153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. FURUE Hidemasa (20304884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HONDA Hiroyuki (20535174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SHIBUE Chieko (90303148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HONMA Takayuki (20345531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Furutani Kenta (40535176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山倉智宏 (80272847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 崎村建司 (40162325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 紙谷義孝 (90381491)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kohno Tatsuro 河野 達郎

KOHNO Tatsuro 河野 達郎

Research Projects

Research Products

Co-Researchers

交番磁界治療器(エイト)の鎮痛機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The elucidation of the brain-spinal cord interactions involved in descending pain modulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the underlying mechanism of acetaminophen in the brain and spinal cordPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Underlynig intracellular signal mechanism of acute tolerance and huperalgesia induced by mu opioidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of mechanism of tourniquet painPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Analysis of inhaled anesthetics on the analgesic effect and immobilization in the spinal cordPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Kohno Tatsuro 河野達郎

KOHNO Tatsuro 河野達郎