ICHIHARA Masatoshi 市原正智

Researcher Number	00314013
Other IDs
Affiliation (Current)	2025: 中部大学, 生命健康科学部, 教授
Affiliation (based on the past Project Information) *help	2006 – 2023: Chubu University, Life Health Sciences, Professor, 生命健康科学部, 教授 2004 – 2005: 名古屋大学, 医学部, 助教授 2002 – 2003: 名古屋大学, 大学院・医学系研究科, 講師 2001: Graduate School of Medicine, Assistant Professor, 大学院・医学研究科, 講師 2000: 名古屋大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Experimental pathology / Experimental pathology / Hygiene / Basic Section 55040:Respiratory surgery-related / Laboratory animal science Except Principal Investigator Experimental pathology / Basic Section 59040:Nutrition science and health science-related / Basic Section 49030:Experimental pathology-related / Applied genomics
Keywords	Principal Investigator RET / GDNF / POZ / BTB / ureteric bud / neurite outgrowth / 胸腺腫 / ERK / SPROUTY / HOXA10 … More / GZF1 / tubulin / SEP1 / kidney development / inducible gene / neuronal differentiation / 酸化ストレス / 分子状水素 / 遺伝子変異 / 胸腺腫発症ラット / B型胸腺腫 / ゲノム編集 / ミトコンドリア / 次世代シークエンス / 筋萎縮 / kidney develoment / zinc fingerprotein / neurite o utgrowth / zinc finger protein / 発癌 / 扁平上皮癌 / 水素 / 炎症 / 線虫 / 皮膚癌 / 紫外線 / MS / LC / LC/MS / isoform / DNAマイクロアレイ / アイソフォーム / チロシンキナーゼ / パーキンソン病 / ヒドロキシラジカル / 活性酸素 / 住環境 … More Except Principal Investigator トランスジェニックマウス / マイクロRNA / アンジオテンシン変換酵素 / マイクロＲＮＡ / 拡張型心筋症 / JNK / RET / GDNF / MAS1 / ヘキソキナーゼ２ / 発癌 / 大腸癌 / 疾患モデル動物 / 精子形成 / REV7コンディショナルノックアウトマウス / 結合蛋白 / プロモーター解析 / 遺伝子発現 / 精子形成不全 / マイクロアレイ解析 / 生殖細胞 / 精巣 / コンディショナルノックアウトマウス / REV7 / 精原幹細胞 / 配偶子形成 / ヘキソキナーゼ2 / 酸化還元ストレス / IGF1受容体 / p62 / MAS / ペントースリン酸経路 / インスリン様成長因子１受容体 / グルタチオン / 心筋症 / knock-in mice / enteric nervous system / cell movement / protein kinase A / tyrosine kinase / 腎臓 / 発がん / ノックアウトマウス / 形態形成 / 遺伝子改変マウス / RETチロシンキナーゼ / ノックインマウス / 腸管神経系 / 細胞運動 / プロテインキナーゼA / チロシンキナーゼ / 心筋細胞 / 心不全 / p68/p72 / c-Myc / 癌 / マイクロ RNA / 発生 / microRNA / 疾患動物モデル / least square linear fitting / mRNA secondary structure / prediction / siRNA Less

胸腺腫発症ラットの原因遺伝子変異導入マウスを用いたヒトB型胸腺腫の病態解明Principal Investigator
- Principal Investigator
  
  市原正智
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Chubu University
Pathophysiological analysis of animal models of disease with the goal of establishing animal models of sarcopenia
- Principal Investigator
  
  Sobue Sayaka
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Chubu University
Elucidation of novel molecular mechanisms for maintenance of spermatogonial stem cells and gametogenesis in the testis
- Principal Investigator
  
  Murakumo Yoshiki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kitasato University
Analysis of signaling of Hexokinase 2 and MAS receptor in the cardiomyopathy overexpressing a set of microRNA
- Principal Investigator
  
  IWAMOTO Takashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Chubu University
Identification and functional analysis of causative genes for thymoma and muscle atrophy developing in BUF/Mna ratsPrincipal Investigator
- Principal Investigator
  
  ICHIHARA Masatoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Chubu University
Analysis of mechanisms of overexpression of angiotensin converting enzyme and heart failure in transgenic mice of miRNAs
- Principal Investigator
  
  IWAMOTO Takashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Chubu University
Molecular hydrogen attenuates UV-induced tissue injury in Caenorhabditis elegans and mousePrincipal Investigator
- Principal Investigator
  
  ICHIHARA Masatoshi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Chubu University
Analysis of microRNA function on heart and smooth muscles and itsanti-tumor effect using genetically modified mice
- Principal Investigator
  
  IWAMOTO Takashi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Chubu University
New approach for health maintenanceand disease control by modification of inhaled air compositionPrincipal Investigator
- Principal Investigator
  
  ICHIHARA Masatoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Hygiene
- Research Institution
  Chubu University
Identification of downstream regulatory factor in RET signaling pathway and its application to cancer treatmentPrincipal Investigator
- Principal Investigator
  
  ICHIHARA Masatoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Chubu University
Analysis of development and cancer in microRNA transgenic mice
- Principal Investigator
  
  IWAMOTO Takashi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Chubu University
mRNAの1次塩基配列と2次構造予測に基づくsiRNA設計アルゴリズムの開発研究
- Principal Investigator
  
  OHNO Kinji
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied genomics
- Research Institution
  Nagoya University
Sprouty family of proteins regulates organogenesis and carcinogenesis through the signaling caused by RET tyrosine kinasePrincipal Investigator
- Principal Investigator
  
  ICHIHARA Masatoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Chubu University
GDNF-inducible zinc finger protein 1 regulates organogenesis as a sequence specific transcriptional repressorPrincipal Investigator
- Principal Investigator
  
  ICHIHARA Masatoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Nagoya University
In vivo role of the GDNF/RET signaling pathway in morphogenesis and pathogenesis
- Principal Investigator
  
  TAKAHASHI Masahide
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Nagoya University
Glial Cell line-derived neurotrophic factor (GDNF) inducible genes regulate neuronal differentiation and kidney developmentPrincipal Investigator
- Principal Investigator
  
  ICHIHARA Masatoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Nagoya University
Glial cell line-derived neurtftrophic factor (GDNF) inducible genes and neuronal differentiationPrincipal Investigator
- Principal Investigator
  
  ICHIHARA Masatoshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Nagoya University

All 2024 2020 2018 2017 2016 2015 2014 2012 2010 2009 2008 2007 2004 Other

All Journal Article Presentation

[Journal Article] REV7 is involved in outcomes of platinum-based chemotherapy in pancreatic cancer via controlling the DNA damage response2024
- Author(s)
  Akihiro Tamaki, Takuya Kato, Yasutaka Sakurai, Keita Sato, Kai Adachi, Masayoshi Tadehara, Taro Kogami, Masahiro Matsushita, Akiyoshi Hoshino, Itaru Sanoyama, Yoshiko Numata, Atsuko Umezawa, Masaaki Ichinoe, Masatoshi Ichihara, Chika Kusano, Yoshiki Murakumo
- Journal Title
  
  Cancer Science
  
  Volume: Volume115, Issue2 Issue: 2 Pages: 660-671
- DOI
  10.1111/cas.16044
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15414, KAKENHI-PROJECT-21K06894, KAKENHI-PROJECT-21K06973, KAKENHI-PROJECT-23K06486, KAKENHI-PROJECT-23K08306
[Journal Article] CD109 Attenuates Bleomycin-induced Pulmonary Fibrosis by Inhibiting TGF-β Signaling2024
- Author(s)
  Naoi Hyogo、Suzuki Yuzo、Miyagi Asuka、Horiguchi Ryo、Aono Yuya、Inoue Yusuke、Yasui Hideki、Hozumi Hironao、Karayama Masato、Furuhashi Kazuki、Enomoto Noriyuki、Fujisawa Tomoyuki、Inui Naoki、Mii Shinji、Ichihara Masatoshi、Takahashi Masahide、Suda Takafumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 212 Issue: 7 Pages: 1221-1231
- DOI
  10.4049/jimmunol.2300285
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08279, KAKENHI-PROJECT-23K07598, KAKENHI-PROJECT-23K08306, KAKENHI-PROJECT-21K08176
[Journal Article] Inactivation of REV7 enhances chemosensitivity and overcomes acquired chemoresistance in testicular germ cell tumors.2020
- Author(s)
  Sakurai Y, Ichinoe M, Yoshida K, Nakazato Y, Saito S, Satoh M, Nakada N, Sanoyama I, Umezawa A, Numata Y, Shi-Xu J, Ichihara M, Takahashi M, Murakumo Y
- Journal Title
  
  Cancer Lett.
  
  Volume: 489 Pages: 100-110
- DOI
  10.1016/j.canlet.2020.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09011, KAKENHI-PROJECT-19K16616, KAKENHI-PROJECT-18H02643
[Journal Article] Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension2018
- Author(s)
  Matsuoka Hiroki、Miyata Seiko、Okumura Nozomi、Watanabe Takuya、Hashimoto Katsunori、Nagahara Miki、Kato Kazuko、Sobue Sayaka、Takeda Kozue、Ichihara Masatoshi、Iwamoto Takashi、Noda Akiko
- Journal Title
  
  Clinical and Experimental Hypertension
  
  Volume: 41 Issue: 4 Pages: 307-311
- DOI
  10.1080/10641963.2018.1481419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16600, KAKENHI-PROJECT-16K08748
[Journal Article] 分子状水素によるマウス肝臓における遺伝子発現変化の解析2016
- Author(s)
  祖父江沙矢加、市原正智
- Journal Title
  
  中部大学生命健康科学研究所紀要
  
  Volume: 12 Pages: 38-41
- NAID
  120006520501
- Open Access
- Data Source
  KAKENHI-PROJECT-15K06812
[Journal Article] Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells.2016
- Author(s)
  Mizutani N, Omori Y, Kawamoto Y, Sobue S, Ichihara M, Suzuki M, Kyogashima M, Nakamura M, Tamiya-Koizumi K, Nozawa Y, Murate T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 470 Issue: 4 Pages: 851-856
- DOI
  10.1016/j.bbrc.2016.01.134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06812, KAKENHI-PROJECT-26870682, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-26670625, KAKENHI-PROJECT-26290051, KAKENHI-PROJECT-26460674
[Journal Article] 分子状水素によるマウス肝臓における遺伝子発現変化の解析2016
- Author(s)
  祖父江沙矢加、市原正智
- Journal Title
  
  中部大学生命健康科学研究所紀要
  
  Volume: 12 Pages: 38-41
- NAID
  120006520501
- Open Access
- Data Source
  KAKENHI-PROJECT-24590768
[Journal Article] Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents.2015
- Author(s)
  Sobue S, Yamai K, Ito M, Ohno K, Ito M, Iwamoto T, Qiao S, Ohkuwa T, Ichihara M
- Journal Title
  
  Mol Cell Biochem.
  
  Volume: 403 Issue: 1-2 Pages: 231-241
- DOI
  10.1007/s11010-015-2353-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-25460506
[Journal Article] Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles.2015
- Author(s)
  Ichihara M, Sobue S, Ito M, Ito M, Hirayama M, Ohno K.
- Journal Title
  
  Med Gas Res
  
  Volume: 5 Issue: 1 Pages: 12-12
- DOI
  10.1186/s13618-015-0035-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06812, KAKENHI-PROJECT-15K09350, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-26870682, KAKENHI-PROJECT-24590768
[Journal Article] Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents.2015
- Author(s)
  Sobue S, Yamai K, Ito M, Ohno K, Ito M, Iwamoto T, Qiao S, Ohkuwa T, Ichihara M
- Journal Title
  
  Mol Cell Biochem
  
  Volume: 403 Pages: 231-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590768
[Journal Article] Photoshopを用いた画像解析の検討.2014
- Author(s)
  岩田晃裕、土本詩織、市原正智、祖父江沙矢加
- Journal Title
  
  社団法人　愛知県臨床衛生検査技師会誌　らぼ
  
  Volume: 65 Pages: 11-14
- Data Source
  KAKENHI-PROJECT-24590768
[Journal Article] Forced Expression of miR-143 Represses ERK5/c-Myc and p68/p72 Signaling in Concert with miR-145 in Gut Tumors of ApcMin Mice.2012
- Author(s)
  Takaoka Y., Shimizu Y., Hasegawa H., Ouchi Y., Qiao S., Nagahara M., Ichihara M., Lee J.D., Adachi K., Hamaguchi M., Iwamoto T.
- Journal Title
  
  PLoS ONE
  
  Volume: 7(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590369
[Journal Article] ATRA inhibits ceramide kinase transcription in a human neuroblastoma cell line, SH-SY5Y cells : the role of COUP-TFI.2010
- Author(s)
  Murakami M, Ito H, Hagiwara K, Yoshida K, Sobue S, Ichihara M, Takagi A, Kojima T, Tanaka K, Tamiya-Koizumi K, Kyogashima M, Suzuki M, Banno Y, Nozawa Y, Murate T.
- Journal Title
  
  J Neurochem. 112(2)
  
  Pages: 511-520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] ATRA inhibits ceramide kinase transcription in a human neuroblastoma cell line, SH-SY5Y cells : the role of COUP-TFI.2010
- Author(s)
  Murakami M, Ito H, Hagiwara K, Yoshida K, Sobue S, Ichihara M, Takagi A, Kojima T, Tanaka K, Tamiya-Koizumi K, Kyogashima M, Suzuki M, Banno Y, Nozawa Y, Murate T
- Journal Title
  
  J Neurochem. 112
  
  Pages: 511-520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590412
[Journal Article] Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease.2009
- Author(s)
  Fu Y, Ito M, Fujita Y, Ichihara M, Masuda A, Suzuki Y, Maesawa S, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K
- Journal Title
  
  Neurosci Lett. 453
  
  Pages: 81-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590412
[Journal Article] Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells.2009
- Author(s)
  Itoh T, Fujita Y, Ito M, Masuda A, Ohno K, Ichihara M, Kojima T, Nozawa Y, Ito M.
- Journal Title
  
  Biochem Biophys Res Commun. 389(4)
  
  Pages: 651-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] Increased expression of glial cell line-derived neurotrophic factor and neurturin in a case of colon adenocarcinoma associated with diffuse ganglioneuromatosis.2009
- Author(s)
  Qiao S, Iwashita T, Ichihara M, Murakumo Y, Yamaguchi A, Isogai M, Sakata K, Takahashi M
- Journal Title
  
  Clin Neuropathol. 28
  
  Pages: 105-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590412
[Journal Article] Increased expression of glial cell line-derived neurotrophic factor and neurturin in a case of colon adenocarcinoma associated with diffuse ganglioneuromatosis.2009
- Author(s)
  Qiao S, Iwashita T, Ichihara M, Murakumo Y, Yamaguchi A, Isogai M, Sakata K, Takahashi M.
- Journal Title
  
  Clin Neuropathol. 28(2)
  
  Pages: 105-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease.2009
- Author(s)
  Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, Masuda A, Suzuki Y, Maesawa S, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K.
- Journal Title
  
  Neurosci Lett. 453(2)
  
  Pages: 81-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells.2009
- Author(s)
  Itoh T, Fujita Y, Ito M, Masuda A, Ohno K, Ichihara M, Kojima T, Nozawa Y
- Journal Title
  
  Biochem Biophys Res Commun. 389
  
  Pages: 651-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590412
[Journal Article] A novel GDNF-inducible gene, BMZF3, encodes a transcriptional repressor associated with KAP-1.2008
- Author(s)
  Suzuki C, Murakumo Y, Kawase Y, Sato T, Morinaga T, Fukuda N, Enomoto A, Ichihara M, Takahashi M
- Journal Title
  
  Biochem Biophys Res Commun. 366
  
  Pages: 226-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590412
[Journal Article] Roles of induced expression of MAPK phosphatase-2 in tumor development in RET-MEN2A transgenic mice.2008
- Author(s)
  Hasegawa T, Enomoto A, Kato T, Kawai K, Miyamoto R, Jijiwa M, Ichihara M, Ishida M, Asai N, Murakumo Y, Ohara K, Niwa Y, Goto H, Takahashi M.
- Journal Title
  
  Oncogene. 27(43)
  
  Pages: 5684-5695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200021
[Journal Article] Roles of induced expression of MAPK phosphatase-2 in tumor development in RET-MEN2A transgenic mice.2008
- Author(s)
  Hasegawa T, Enomoto A, Kato T, Kawai K, Miyamoto R, Jijiwa M, Ichihara M, Ishida M, Asai N, Murakumo Y, Ohara K, Niwa Y, Goto H, Takahashi M
- Journal Title
  
  Oncogene. 27
  
  Pages: 5684-5695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590412
[Journal Article] Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities2007
- Author(s)
  Ichihara M
- Journal Title
  
  Nucleic Acids Res 35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590367
[Journal Article] Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities.2007
- Author(s)
  Ichihara M
- Journal Title
  
  Nucleic Acids Res. 35(peer reviewed)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590367
[Journal Article] RET and neuroendocrine tumors2004
- Author(s)
  Masatoshi Ichihara
- Journal Title
  
  Cancer Letters 204
  
  Pages: 197-211
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209014
[Journal Article] RET and neuroendocrine tumors.2004
- Author(s)
  Masatoshi Ichihara et al.
- Journal Title
  
  Cancer Lett. 204
  
  Pages: 197-211
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209014
[Presentation] 低酸素環境におけるRET変異体の機能解析2017
- Author(s)
  善楼楼、加藤智也、小澄璃奈、川本善之、武田湖州恵、市原正智、岩本隆司
- Organizer
  conbio 2017
- Data Source
  KAKENHI-PROJECT-16K08748
[Presentation] 水素ガスおよび水素水の併用投与が細胞内シグナル伝達に与える影響の検討2015
- Author(s)
  祖父江沙矢加、井上千聖、伊藤美佳子、大野欽司、伊藤雅史、市原正智
- Organizer
  第5回分子状水素医学シンポジウム
- Place of Presentation
  ウインクあいち (名古屋市)
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] Development of effective method for preventing life environment factor-induced diseases using molecular hydrogen.2015
- Author(s)
  Sobue S, Ichihara M.
- Organizer
  ICITE for SD-2015
- Place of Presentation
  Chubu University (Kasugai)
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06812
[Presentation] Molecular hydrogen is a novel antioxidant to reduce oxidative stress and attenuate disease progression through modification of cell signaling and gene expressions.2015
- Author(s)
  Sobue S, Inoue C, Hori F, Ito M, Ohno K, Ichihara M.
- Organizer
  15th International Conference on Oxidative Stress Reduction, Redox Homeostasis &Antioxidants
- Place of Presentation
  Paris (France)
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06812
[Presentation] Development of effective method for preventing life environment factor-induced diseases using molecular hydrogen.2015
- Author(s)
  Sobue S, Ichihara M.
- Organizer
  ICITE for SD-2015
- Place of Presentation
  Chubu University (Kasugai)
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] Molecular hydrogen is a novel antioxidant to reduce oxidative stress and attenuate disease progression through modification of cell signaling and gene expressions.2015
- Author(s)
  Sobue S, Inoue C, Hori F, Ito M, Ohno K, Ichihara M.
- Organizer
  15th International Conference on Oxidative Stress Reduction, Redox Homeostasis &Antioxidants
- Place of Presentation
  Paris (France)
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] UVB照射ケラチノサイトは炎症性サイトカインを分泌してメラノサイトにおける癌関連GD3合成酵素遺伝子の発現を誘導する2014
- Author(s)
  古川圭子、宮田麻衣子、田島織絵、神戸真理子、市原正智、祖父江沙矢加、古川鋼一
- Organizer
  第73回日本癌学会
- Place of Presentation
  パシフィコ横浜 (横浜市)
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] 肺に著明なpanmyelosisが認められ、呼吸不全によって死亡したatypical CMLの1剖検例2014
- Author(s)
  白木之浩、市原正智、三井伸二、浅井直也、榎本篤、岩田洋介、伊藤雅文、高橋雅英
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会議場 (広島市)
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] 遺伝子改変マウスを用いた癌関連タンパクCD109の機能解析および新規腫瘍マーカーへの応用可能性2014
- Author(s)
  三井伸二、村雲芳樹、坂倉寛紀、浅井真人、浅井直也、市原正智、高橋雅英
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会議場 (広島市)
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] 分子状水素によるI型アレルギー抑制の分子機構2010
- Author(s)
  伊藤智広、藤田泰典、伊藤美佳子、増田章男、市原正智、小島俊男、野澤義則、大野欽司、伊藤雅史
- Organizer
  第130回日本薬学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20590412
[Presentation] Cereulide毒素による肝障害に対する分子状水素の肝保護効果の検討2010
- Author(s)
  祖父江沙矢加、岡本陽、安形則雄、市原正智
- Organizer
  BMB2010
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] 分子状水素によるI型アレルギー抑制機構の解明2010
- Author(s)
  伊藤智広、藤田泰典、伊藤美佳子、増田章男、市原正智、小島俊男、野澤義則、大野欽司、伊藤雅史
- Organizer
  日本基礎老化学会第33回大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] 水素水投与後の血中・臓器濃度と肝臓内酸化ストレス軽減効果の検討2010
- Author(s)
  市原正智
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20590412
[Presentation] 水素水投与後の血中・臓器濃度と肝臓内酸化ストレス軽減効果の検討2010
- Author(s)
  市原正智、祖父江沙矢加、山井一晃、大桑哲男
- Organizer
  BMB2010
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] 水素水投与後の血中・臓器濃度と肝臓内酸化ストレス軽減効果の検討2010
- Author(s)
  市原正智、祖父江沙矢加、山井一晃、大桑哲男
- Organizer
  BMB2010
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590412
[Presentation] 分子状水素によるI型アレルギー抑制の分子機構2010
- Author(s)
  伊藤智広、藤田泰典、伊藤美佳子、増田章男、市原正智、小島俊男、野澤義則、大野欽司、伊藤雅史
- Organizer
  第130回日本薬学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] Cereulide毒素による肝障害に対する分子状水素の肝保護効果の検討2010
- Author(s)
  祖父江沙矢加、岡本陽、安形則雄、市原正智
- Organizer
  BMB2010
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590412
[Presentation] 水素水投与後の血中水素濃度動態の検討2010
- Author(s)
  山井一晃、祖父江沙矢加、大桑哲男、市原正智
- Organizer
  第2回水素研究会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-02-12
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] 分子状水素によるI型アレルギー抑制機構の解明2010
- Author(s)
  伊藤智広、藤田泰典、伊藤美佳子、増田章男、市原正智、小島俊男、野澤義則、大野欽司、伊藤雅史
- Organizer
  日本基礎老化学会第33回大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590412
[Presentation] 水素水投与後の血中水素濃度動態の検討2010
- Author(s)
  山井一晃、祖父江沙矢加、大桑哲男、市原正智
- Organizer
  第2回水素研究会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-02-12
- Data Source
  KAKENHI-PROJECT-20590412
[Presentation] 水素水投与後の血中・臓器濃度と肝臓内酸化ストレス軽減効果の検討2010
- Author(s)
  市原正智
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] v-SrcによるSPHK1 mRNA安定化と発現増強2008
- Author(s)
  祖父江沙矢加、村上真史、坂野喜子、伊藤裕美、高四強、古畑彩子、高木明、小嶋哲人、野澤義則、村手隆、市原正智
- Organizer
  BMB 2008
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20200021
[Presentation] 基底細胞型乳癌の新しいマーカーとてのCD1092008
- Author(s)
  長谷川正規、森谷鈴子、三井伸二、佐藤朋子、時々輪真由美、村雲芳樹、市原周、高橋雅英
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-20590412
[Presentation] v-SrcによるSPHK1 mRNA安定化と発現増強2008
- Author(s)
  祖父江沙矢加、村上真史、坂野喜子、伊藤裕美、高四強、古畑彩子、高木明、小嶋哲人、野澤義則、村手隆、市原正智
- Organizer
  BMB2008
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590412
[Presentation] UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6
- Author(s)
  Keiko Furukawa, Maiko Miyata, Masatoshi Ichihara, Orie Tajima, Sayaka Sobue, Mariko Kambe, Kazumitsu Sugiura, Koichi Furukawa
- Organizer
  9th International Symposium Glycosyltransferase (Glyco-T 2014)
- Place of Presentation
  Porto (Portugal)
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-24590768
[Presentation] 剖検を模した条件下での死後変化に伴う経時的遺伝子発現変化のパラフィン標本由来RNAなどを用いた検討
- Author(s)
  市原正智
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌 (札幌市)
- Data Source
  KAKENHI-PROJECT-24590768

1. MURAKUMO Yoshiki (40324438)

# of Collaborated Projects: 9 results

# of Collaborated Products: 7 results
2. IWAMOTO Takashi (60223426)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
3. SOBUE Sayaka (50513347)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
4. TAKAHASHI Masahide (40183446)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. OHNO Kinji (80397455)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. UEYAMA Tomomi (80379388)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. OUCHI Yasuo (70553858)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. NODA Akiko (80252287)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KATO Masashi (10281073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TAKEUCHI Tamaki (90392018)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MASUDA Akio (10343203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. YONEDA Makoto (70270551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ITO Masafumi (80393114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
14. QIAO Shanlou (00343658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. NAKAYAMA Shinsuke (30192230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MURAKAMI Hideki (90303619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. JIJIWA Mayumi (50378006)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 小形岳寛 (10402877)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 上田潤 (80450394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 櫻井靖高 (50733101)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 一戸昌明 (80365163)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 吉田松生 (60294138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 後藤亜由美 (20780969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 三井伸二 (80646505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. MIKAKO Ito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 宮田聖子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 眞山到

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 鈴木勇三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 佐藤雅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ICHIHARA Masatoshi 市原 正智

Research Projects

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Co-Researchers

胸腺腫発症ラットの原因遺伝子変異導入マウスを用いたヒトB型胸腺腫の病態解明Principal Investigator

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Identification and functional analysis of causative genes for thymoma and muscle atrophy developing in BUF/Mna ratsPrincipal Investigator

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Molecular hydrogen attenuates UV-induced tissue injury in Caenorhabditis elegans and mousePrincipal Investigator

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New approach for health maintenanceand disease control by modification of inhaled air compositionPrincipal Investigator

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Identification of downstream regulatory factor in RET signaling pathway and its application to cancer treatmentPrincipal Investigator

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Sprouty family of proteins regulates organogenesis and carcinogenesis through the signaling caused by RET tyrosine kinasePrincipal Investigator

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GDNF-inducible zinc finger protein 1 regulates organogenesis as a sequence specific transcriptional repressorPrincipal Investigator

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ICHIHARA Masatoshi 市原正智