IJIRI Kosei 井尻幸成

Researcher Number	00315417
Other IDs
Affiliation (based on the past Project Information) *help	2014: 鹿児島大学, 医歯(薬)学総合研究科, 客員研究員 2013: 鹿児島大学, 医歯研, 客員研究員 2011 – 2013: 鹿児島大学, 医歯(薬)学総合研究科, 准教授 2011: 鹿児島大学, 大学院・医歯学総合研究科, 准教授 2010 – 2011: Kagoshima University, 医歯学総合研究科, 准教授 … More 2007 – 2009: Kagoshima University, Graduate School of Medical and Dental Sciences, Associate Professor 2006: 鹿児島大学, 医学部・歯学部附属病院, 講師 2001 – 2002: 鹿児島大学, 医学部, 講師 2000: 鹿児島大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery / Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Rehabilitation science/Welfare engineering / Orthopaedic surgery
Keywords	Principal Investigator OA / GADD45beta / Osteoporosis / Apoptosis / sFRPs / 軟骨細胞 / 変形性関節症 / osteoarthritis / 軟骨 / C/EBPbeta … More / Gadd45beta / 関節病学 / Hypertrophic chondrocyte / マウス / GADD45b / 肥大軟骨細胞 / Secreted frizzled related protein / Monocyte / 分子生物学 / 骨形態計測 / Secreted related protein / 骨粗鬆症 / 関節軟骨 / 石灰化 / 肥大化 / C/EBPβ / GADD45β / 肥大軟骨 / gadd45beta / apoptosis / cartilage / EBPbeta / C / アポトーシス … More Except Principal Investigator Cbl / Src / 運動療法 / リハビリテーション / Signal transduction / Rheumatoid arthritis / c-Cbl / ユビキチン / 破骨細胞 / 骨吸収 / 細胞内情報伝達 / 関節リウマチ / メカニズム / 神経保護 / 脳梗塞 / ロボットスーツHAL / 早期運動療法 / 機能回復促進 / 脳神経保護 / 神経栄養因子 / 脳神経保護作用 / NO / Beclin / 関節軟骨変性 / 神経変性 / 老化 / オートファジー / トレッドミル運動 / 脊髄前角細胞 / ベクリン / 脊髄変性 / 加齢 / 運動 / 脊髄 / 老化促進マウス Less

Fundamental researches to presentation a new animal models and the therapy development of the osteoarthritisPrincipal Investigator
- Principal Investigator
  
  IJIRI KOSEI
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Neurorepair and functional recovery by motor exercise in rats after ischemia reperfusion
- Principal Investigator
  
  HARUTOSHI Sakakima
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Kagoshima University
Effect of exercise on the aging-degeneration in senescence-accelerated mouse's locomotorium
- Principal Investigator
  
  YONE Kazunori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Molecular mechanism of osteoarthritis-analysis of Gadd45beta transgenic mice-Principal Investigator
- Principal Investigator
  
  IJIRI Kosei
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Pathological mechanism of osteoarthritis -analysis of molecules responsing to mechanical stress-Principal Investigator
- Principal Investigator
  
  IJIRI Kosei
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Ubiquitin system of Src-Cbl negatively regulating the signal transduction of osteoclasts in rheumatoid arthritis
- Principal Investigator
  
  KOMIYA Setsuro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University
Biological study for osteoporosis -Apoptosis related gene expression-Principal Investigator
- Principal Investigator
  
  IJIRI Kosei
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kagoshima University

All 2013 2011 2010 2009 2008 2006

All Journal Article Presentation

[Journal Article] A newly developed robot suit hybrid assistive limb (HAL) facilitated walking rehabilitation after spinal surgery for thoracic ossification of the posterior longitudinal ligament: A case report2013
- Author(s)
  Harutoshi Sakakima, Kosei Ijiri, Fumiyo Matsuda, Hiroyuki Tominaga, Takanori Biwa, Kazunori Yone, Yoshiyuki Sankai
- Journal Title
  
  Case Reports in Orthopedics
  
  Volume: ID 621405 Pages: 1-4
- DOI
  10.1155/2013/621405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500590
[Journal Article] Senescence of chondrocytes in aging articular cartilage : GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice2011
- Author(s)
  Shimada H, Ijiri K, et al
- Journal Title
  
  Pathol Res Pract
  
  Volume: 207(4) Pages: 225-231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390369
[Journal Article] Senescence of chondrocytes in aging articular cartilage : GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice.2011
- Author(s)
  Shimada H, Sakakima H, Tsuchimochi K, Matsuda F, Komiya S, Goldring MB, Ijiri K.
- Journal Title
  
  Pathol Res Pract. 207(4)
  
  Pages: 225-231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591787
[Journal Article] Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth2011
- Author(s)
  Kawabata N, Ijiri K, et al
- Journal Title
  
  Int J Oncol
  
  Volume: 39(4) Pages: 899-906
- NAID
  120005342568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390369
[Journal Article] Senescence of chondrocytes in aging articular cartilage: Gadd45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice.2011
- Author(s)
  Shimada H, Sakakoma H, Tsuchimochi K, Matsuda F, komiya S, Goldring MB, Ijiri K
- Journal Title
  
  Pathol Res Pract
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591787
[Journal Article] GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes2010
- Author(s)
  Tchimochi K, Otero M, Dragomir CL, Plumb DA, Zerbini LF, Libermann TA, Marcu KB, Komiya S, Ijiri K, Goldring MB.
- Journal Title
  
  J Biol Chem 285
  
  Pages: 8395-407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591787
[Journal Article] GADD45beta enhances Col10a1 trans cription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes.2010
- Author(s)
  Tsuchimochi K, Otero M, Dragomir CL, Plumb DA, Zerbini LF, Libermann TA, Marcu KB, Komiya S, Ijiri K, Goldring MB.
- Journal Title
  
  J Biol Chem. 285(11)
  
  Pages: 8395-8407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591787
[Journal Article] Gadd45beta expression in chondrosarcoma : A pilot study for diagnost ic and biological inplications in histological grading.2010
- Author(s)
  M Zenmyo, A Tanimoto, H Sakakima, M Yokouchi, S Nagano, T Yamamoto, Y Ishido, S Komioya, K Ijiri
- Journal Title
  
  Diagnostic Pathology 5(1)
  
  Pages: 69-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591787
[Journal Article] Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha.2009
- Author(s)
  Izumi T, Fujii R, Izumi T, Nakazawa M, Yagishita N, Tsuchimochi K, Yamano Y, Sato T, Fujita H, Aratani S, Araya N, Azakami K, Hasegawa D, Kasaoka S, Tsuruta R, Yokouti M, Ijiri K, Beppu M, Maruyama I, Nishioka K, Maekawa T, Komiya S, Nakajima T.
- Journal Title
  
  Arthritis Rheum. 60(1)
  
  Pages: 63-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591787
[Journal Article] ESE-1 is a Potent Pepressor of Type II Collagen Gene (LOL2A1) Transcription in Human Chondrocytes2008
- Author(s)
  Peng, H., Tan, L., Osaki, M., Zhan, Y., Ijiri, K., Tsuchimochi, K., Otero, M., Wang, H., Choy, BK., Grail, FT., Gu, X., Libermann, TA., Oettgen, P., Goldring, MB
- Journal Title
  
  J Cell Physiol 215
  
  Pages: 562-573
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591636
[Journal Article] Differential Expression of GADD45 β in Normal and Osteoarthritic Cartilage Potential Role in Homeostasis of Articular Chondrocytes2008
- Author(s)
  Kosei Ijiri
- Journal Title
  
  Arthritis Rheumatism 58
  
  Pages: 2075-2087
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591636
[Journal Article] Differential expression of GADD45b in normal and osteoarthritic cartilage: Potential role in homeostasis of articular chondrocyte2008
- Author(s)
  Ijiri K, Zerbini FL, et. al.
- Journal Title
  
  Arthritis & Rheumatism (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591636
[Journal Article] Differential expression of GADD45beta in normal and osteoarthritic cartilage : potential role in homeostasis of articular chondrocytes.2008
- Author(s)
  Ijiri K
- Journal Title
  
  Arthritis Rheumatism 58
  
  Pages: 2075-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591787
[Journal Article] Differential Expression of GADD45β in Normal and Osteoarthritic Cartilage Potential Role in Homeostasis of Articular Chondrocytes2008
- Author(s)
  Ijiri, K., Zerbini, L., Peng, H., Out, HH., Tsuchimochi, K., Otero, M., Dragomir, C., Walsh, N., Bierbaum, BE., Mattingly, D., Flandern, G., Komiya, S., Aigner, T., Libermann, TA., Goldring, MB
- Journal Title
  
  Arthritis Rheum 58
  
  Pages: 2075-2087
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591636
[Journal Article] The cnotrol of chondrogenesis.2006
- Author(s)
  Goldring MG, Tsuchimochi K, Ijiri K.
- Journal Title
  
  J Cell Biochem 97(1)
  
  Pages: 33-44
- Data Source
  KAKENHI-PROJECT-18591636
[Journal Article] Midkine and its receptor in regenerating rat skeletal muscle after bupivacaine injection.2006
- Author(s)
  Sakakima H, Kamizono T, Matsuda F, Izumo K, Ijiri K, Yoshida Y.
- Journal Title
  
  Acta Hitochem 108(5)
  
  Pages: 357-63
- Data Source
  KAKENHI-PROJECT-18591636
[Presentation] Newly Developed Wearable Robot Facilitated Waking Rehabilitation for Patient with Spinal Surgery: A Case Study2013
- Author(s)
  8. Harutoshi Sakakima, Kosei Ijiri, Fumiyo Matsuda, Kazunori Yone
- Organizer
  ACRM Annual Conference
- Place of Presentation
  Orland (USA)
- Data Source
  KAKENHI-PROJECT-23500590
[Presentation] 軟骨細胞におけるC/EBPβによるGADD45βの直接的な制御2013
- Author(s)
  嶋田博文、井尻;幸成、小宮節郎、土持兼之
- Organizer
  第28回　日本整形外科学会基礎学術集会
- Place of Presentation
  千葉市幕張メッセ
- Data Source
  KAKENHI-PROJECT-23390369
[Presentation] 軟骨終末分化においてGadd45βはMTK1/MKK3/6/p38とC/EBPβの活性化を介してCol10a1転写を促進する2010
- Author(s)
  土持兼之, 嶋田博文, 井尻幸成, 小宮節郎, Otero Miguel, Mary B. Goldring
- Organizer
  第23回日本軟骨代謝学会
- Place of Presentation
  鹿児島市
- Data Source
  KAKENHI-PROJECT-20591787
[Presentation] 軟骨終末分化におけるGadd45βによるC/EPBβ活性化分子メカニズム2010
- Author(s)
  土持兼之, 嶋田博文, 井尻幸成, 小宮節郎, Miguel Otero, Mary Goldring
- Organizer
  第25回日本整形外科学会基礎学術集会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-20591787
[Presentation] GADD45β and C/EBPβ distribution in aging articular cartilage of senescence-accelerated mice2009
- Author(s)
  Shimada H, Ijiri K, Komiya S, Sakakima H, Matsuda F, Tsuchimochi K, M.B.Goldring
- Organizer
  55th Annual Meeting of the Orthopaed ic Research Society
- Place of Presentation
  Las Vegas, USA
- Data Source
  KAKENHI-PROJECT-20591787
[Presentation] SAM関節軟骨のGADD45βとC/EBPβの局在～免疫組織学的2009
- Author(s)
  嶋田博文、井尻幸成、小宮節郎, 榊間春利, 松田史代, 土持兼之, Mary B Goldring
- Organizer
  第22回日本軟骨代謝学会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-20591787
[Presentation] マウス関節軟骨におけるGADD45betaの発現-ICRマウスとSAMPマウスを用いて-2008
- Author(s)
  嶋田博文, 井尻幸成, 土持兼之, 小宮節郎, Mary B. Goldring, 榊間春利, 松田史代, 米和徳
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-20591787
[Presentation] 関節軟骨におけるGADD45betaの遺伝子発現-OAの進行とその発現量変化-2008
- Author(s)
  井尻幸成, 土持兼之, 嶋田博文, 小宮節郎, Mary B. Goldring, Aigner Thomas
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-20591787
[Presentation] 軟骨細胞終末分化におけるGadd45βの下流ターゲット因子としてのC/EBPβの同定2008
- Author(s)
  土持兼之, 井尻幸成, 嶋田博文, 小宮節郎, Mary Goldring
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-20591787

1. KOMIYA Seturou (30178371)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
2. SAKAKIMA Harutoshi (10325780)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. YONE Kazunori (40182844)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YOSHIDA Yoshihiro (10107906)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MATSUDA Fumiyo (70437953)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. MATSUNAGA Shunji (90229500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SATOSHI Nagano (50373139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TSUYAMA Shinichiro (30041346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OHNISI Toshiyuki (60295243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ISHIDOU Yasuhiro (10300740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YOKOUCHI Masahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IJIRI Kosei 井尻 幸成

Research Projects

Research Products

Co-Researchers

Fundamental researches to presentation a new animal models and the therapy development of the osteoarthritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Neurorepair and functional recovery by motor exercise in rats after ischemia reperfusion

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of exercise on the aging-degeneration in senescence-accelerated mouse's locomotorium

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of osteoarthritis-analysis of Gadd45beta transgenic mice-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathological mechanism of osteoarthritis -analysis of molecules responsing to mechanical stress-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ubiquitin system of Src-Cbl negatively regulating the signal transduction of osteoclasts in rheumatoid arthritis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biological study for osteoporosis -Apoptosis related gene expression-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A newly developed robot suit hybrid assistive limb (HAL) facilitated walking rehabilitation after spinal surgery for thoracic ossification of the posterior longitudinal ligament: A case report2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Senescence of chondrocytes in aging articular cartilage : GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice2011

Author(s)

Journal Title

Data Source

[Journal Article] Senescence of chondrocytes in aging articular cartilage : GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice.2011

Author(s)

Journal Title

Data Source

[Journal Article] Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Senescence of chondrocytes in aging articular cartilage: Gadd45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice.2011

Author(s)

Journal Title

Data Source

[Journal Article] GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes2010

Author(s)

Journal Title

Data Source

[Journal Article] GADD45beta enhances Col10a1 trans cription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes.2010

Author(s)

Journal Title

Data Source

[Journal Article] Gadd45beta expression in chondrosarcoma : A pilot study for diagnost ic and biological inplications in histological grading.2010

Author(s)

Journal Title

Data Source

IJIRI Kosei 井尻幸成