Kawaguchi Takumi 川口巧

… Alternative Names

KAWAGUCHI Takumi 川口巧

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Researcher Number	00320177
Other IDs
Affiliation (Current)	2025: 久留米大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2024: 久留米大学, 医学部, 教授 2022: 久留米大学, 医学部, 教授 2020 – 2021: 久留米大学, 医学部, 准教授 2017 – 2019: 久留米大学, 医学部, 講師 2007 – 2015: Kurume University, 医学部, 講師 2003 – 2006: 久留米大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Gastroenterology / Radiation science / Surgical dentistry
Keywords	Principal Investigator 肝細胞癌 / マイオカイン / 2型糖尿病 / 細胞増殖 / decorin / 非アルコール性脂肪肝炎 / デコリン / 肝癌 / 運動 / insulin receptor substrate … More / ChREBP / 糖尿病 / insulin receptor substrate 1 / HOMA-IR / インスリン情報伝達経路 / mTOR / tuberin / インスリン抵抗性 / 肝硬変 / 代謝異常関連脂肪性肝障害 / 肝がん / レジスタンス運動 / 肝線維化 / 脂肪肝 / 細胞増殖抑制 / 細胞周期 / ワールブルグ効果 / ペントースリン酸経路 / Decorin / イリシン / 運動療法 / サルコペニア / 筋肉量 / 非アルコール性脂肪性肝障害 / HepG2 cell / diabetes mellitus / insulin receptor / gene mutation / insulin secretion / INS-1 cell / luciferase reporter assay / InsZ / 遺伝子導入 / インスリンプロモータ領域 / siRNA / 細胞内局在変化 / Nuclear localization signal / INS-1細胞 / 2 / 肝細胞 / リン酸化 / HepG2細胞 / インスリン受容体 / 遺伝子変異 / インスリン分泌 / INS-1 / ピオグリタゾン / dipeptidyl deptidase-4阻害剤 / glucagon-like peptide-1 / IL-6 / dipeptidyl deptidase-4 / 上皮間葉移行 / 肝臓癌 / 結節性硬化症 / Akt / mammalian target of rapamycin / インスリン / 糖尿病学 … More Except Principal Investigator C型肝炎ウイルス / PYY_<3-36> / NASH / Insulin receptor substrate / HOMA-IR / 酸化ストレス / インスリン抵抗性 / 画像診断 / 非アルコール性脂肪肝疾患 / Fat fraction / IDEAL-IQ / 異所性脂肪組織 / 非アルコール性脂肪肝炎 / 糖尿病 / PDFF / MRI / 非アルコール性脂肪性肝疾患 / 異所性脂肪 / Oxidative stress / Fatty liver / 脂肪肝 / HepG2 cell / Intracellular insulin signaling / Interferon / HCV core / Insulin resistance / Hepatitis C virus / インスリンシグナル伝達分子 / SOCS-3 / C型肝炎ウイルスコア抗原 / 一般住民 / C型肝炎ウイルス高感染地区 / ケース・コホート研究 / 2型糖尿病 / C型慢性肝炎 / 免疫染色 / トランスジェニックマウス / ウイルス駆除 / insulin receptor substrate / HepG2細胞 / 細胞内インスリンシグナル / インターフェロン / HCVコア抗原 / データマイニング / 遺伝子解析 / 肝がん / 環境因子 / 宿主因子 / 一塩基多型 / γGTP / Brinkman index / PNPLA3 / アルブミン / 非B非C肝がん / 網羅的解析 / 代謝異常 / 遺伝子異常 / 肝臓がん / システイン / グリチルリチン酸製剤 / 肝細胞癌 / 還元型アルブミン / 酸化型アルブミン / 前癌病変 / C型肝炎ウイルス(HCV) / 歯科医療 / B型肝炎ワクチン / B型肝炎ウイルス / 歯科治療 / スタンダードプレコーション / 消化器内科 / 歯学 / 肝外病変 / 重複癌 / 口腔扁平上皮癌 / 扁平苔癬 Less

レジスタンス運動誘発マイオカインによる肝発がん抑制効果の機序Principal Investigator
- Principal Investigator
  
  川口巧
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kurume University
Effects of myokine decorin on NASH-related hepatocellular carichomaPrincipal Investigator
- Principal Investigator
  
  Kawaguchi Takumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kurume University
Effects of exercise-induced hormon "irisin" on NASH-related hepatomaPrincipal Investigator
- Principal Investigator
  
  Takumi Kawaguchi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
Imaging Biomarker of 3T-MRI in NASH
- Principal Investigator
  
  Tonan Tatsuyuki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kurume University
Identification of new risk factor for nonB, nonC hepatocellular carcinoma: Global analysis using GWAS and data-mining analysis
- Principal Investigator
  
  Sata Michio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
The cytobiological impact of insulin resistance on BMPs-related epithelial-mesenchymal transition of hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  KAWAGUCHI Takumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kurume University
Effects of redox state of albumin on hepatocarcinogenesis
- Principal Investigator
  
  SATA Michio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
The impact of hyperinsulinemia and tuberin in the development of hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  KAWAGUCHI Takumi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kurume University
Relationship between lichen planus, a precancerous lesion, and insulin resistance induced by hepatitis C virus
- Principal Investigator
  
  NAGAO Yumiko
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kurume University
MOLECULAR MECHANISMS FOR THE DEVELOPMENT OF HEPATITIS C VIRUS-RELATED INSULIN RESISTANCE
- Principal Investigator
  
  SATA Michio
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
Research for usefulness of intestinal peptide, PYY_<3-36> for therapeutic agents of fatty liver and NASH
- Principal Investigator
  
  UENO Takato
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
BIOLOGICAL ROLES OF NEW TRANSCRIPTION FACTOR FOR GLUCOSE METABOLISM(ChREBP) IN PANCREATIC ISLET CELLSPrincipal Investigator
- Principal Investigator
  
  KAWAGUCHI Takumi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  KURUME UNIVERSITY SCHOOL OF MEDICINE

[Journal Article] Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma in the era of chemo-diversity2023
- Author(s)
  Iwamoto Hideki、Shimose Shigeo、Shirono Tomotake、Niizeki Takashi、Kawaguchi Takumi
- Journal Title
  
  Clinical and Molecular Hepatology
  
  Volume: － Issue: 3 Pages: 593-604
- DOI
  10.3350/cmh.2022.0391
- Data Source
  KAKENHI-PROJECT-20K08395
[Journal Article] A low-intensity 10-min resistance exercise program that ameliorated hepatic fibrosis indices and altered G-CSF/IP-10/PDGF-BB in a patient with nonalcoholic fatty liver disease: A case report.2023
- Author(s)
  Hashida Ryuki、Nakano Dan、Matsuse Hiroo、Yoshio Sachiyo、Tsutsumi Tsubasa、Kawaguchi Machiko、Koya Shunji、Hirota Keisuke、Tajima Hiroshi、Sumida Yoshio、Kanto Tatsuya、Kawaguchi Takumi、Hiraoka Koji
- Journal Title
  
  JGH Open
  
  Volume: 7 Issue: 3 Pages: 231-234
- DOI
  10.1002/jgh3.12876
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08395, KAKENHI-PROJECT-22K17667
[Journal Article] Leaky gut-derived tumor necrosis factor-α causes sarcopenia in patients with liver cirrhosis2022
- Author(s)
  Kawaguchi Takumi、Torimura Takuji
- Journal Title
  
  Clinical and Molecular Hepatology
  
  Volume: 28 Issue: 2 Pages: 177-180
- DOI
  10.3350/cmh.2021.0246
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08395
[Journal Article] Effects of interleukin-17 inhibitors on hepatic fibrosis index in patients with psoriasis and metabolic dysfunction-associated fatty liver disease: Directed acyclic graphs2022
- Author(s)
  Takamura Saori、Teraki Yuichi、Katayama Eri、Kawaguchi Takumi、Kawaguchi Machiko、Nakano Dan、Tsutsumi Tsubasa、Nagoshi Sumiko、Nakama Takekuni、Torimura Takuji
- Journal Title
  
  Clinical and Molecular Hepatology
  
  Volume: 28 Issue: 2 Pages: 269-272
- DOI
  10.3350/cmh.2022.0040
- Data Source
  KAKENHI-PROJECT-20K08395
[Journal Article] Metabolic dysfunction‐associated fatty liver disease directly related to liver fibrosis independent of insulin resistance, hyperlipidemia, and alcohol intake in morbidly obese patients2022
- Author(s)
  Inamine Susumu、Kage Masayoshi、Akiba Jun、Kawaguchi Takumi、Yoshio Sachiyo、Kawaguchi Machiko、Nakano Dan、Tsutsumi Tsubasa、Hashida Ryuki、Oshiro Kouichi
- Journal Title
  
  Hepatology Research
  
  Volume: 52 Issue: 10 Pages: 841-858
- DOI
  10.1111/hepr.13808
- Data Source
  KAKENHI-PROJECT-20K08395
[Journal Article] Impact of branched-chain amino acids and frailty on the management of lenvatinib-related fatigue in patients with hepatocellular carcinoma2021
- Author(s)
  Shimose Shigeo、Koya Shunji、Kawaguchi Takumi、Hirota Keisuke、Yoshio Sachiyo、Niizeki Takashi、Matsuse Hiroo、Torimura Takuji
- Journal Title
  
  Clinical and Molecular Hepatology
  
  Volume: 27 Issue: 4 Pages: 616-619
- DOI
  10.3350/cmh.2021.0258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08395, KAKENHI-PROJECT-21K08020
[Journal Article] Non-Obese MAFLD Is Associated with Colorectal Adenoma in Health Check Examinees: A Multicenter Retrospective Study2021
- Author(s)
  Fukunaga Shuhei、Nakano Dan、Kawaguchi Takumi、Eslam Mohammed、Ouchi Akihiro、Nagata Tsutomu、Kuroki Hidefumi、Kawata Hidemichi、Abe Hirohiko、Nouno Ryuichi、Kawaguchi Koutaro、George Jacob、Mitsuyama Keiichi、Torimura Takuji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 11 Pages: 5462-5462
- DOI
  10.3390/ijms22115462
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08395
[Journal Article] Association between Activity and Brain-Derived Neurotrophic Factor in Patients with Non-Alcoholic Fatty Liver Disease: A Data-Mining Analysis2021
- Author(s)
  Hashida Ryuki、Nakano Dan、Yamamura Sakura、Kawaguchi Takumi、Tsutsumi Tsubasa、Matsuse Hiroo、Takahashi Hirokazu、Gerber Lynn、Younossi Zobair M.、Torimura Takuji
- Journal Title
  
  Life
  
  Volume: 11 Issue: 8 Pages: 799-799
- DOI
  10.3390/life11080799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08395
[Journal Article] Effects of a low‐intensity resistance exercise program on serum miR‐630, miR‐5703, and Fractalkine/CX3CL1 expressions in subjects with No exercise habits: A preliminary study2021
- Author(s)
  Hashida Ryuki、Matsuse Hiroo、Kawaguchi Takumi、Yoshio Sachiyo、Bekki Masafumi、Iwanaga Sohei、Sugimoto Takahiro、Hara Koji、Koya Shunji、Hirota Keisuke、Nakano Dan、Tsutsumi Tsubasa、Kanto Tatsuya、Torimura Takuji、Shiba Naoto
- Journal Title
  
  Hepatology Research
  
  Volume: 51 Issue: 7 Pages: 823-833
- DOI
  10.1111/hepr.13670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08395, KAKENHI-PROJECT-21K08020
[Journal Article] Slow walking speed overlapped with low handgrip strength in chronic liver disease patients with hepatocellular carcinoma2019
- Author(s)
  Nagamatsu Ayu、Kawaguchi Takumi、Hirota Keisuke、Koya Shunji、Tomita Manabu、Hashida Ryuki、Kida Yohei、Narao Hayato、Manako Yuta、Tanaka Daisuke、Koga Noboru、Nakano Dan、Niizeki Takashi、Matsuse Hiroo、Torimura Takuji、Shiba Naoto
- Journal Title
  
  Hepatology Research
  
  Volume: 49 Issue: 12 Pages: 1427-1440
- DOI
  10.1111/hepr.13405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09444
[Journal Article] Clinical utility of the Liver Frailty Index for predicting muscle atrophy in chronic liver disease patients with hepatocellular carcinoma2019
- Author(s)
  Hirota Keisuke、Kawaguchi Takumi、Koya Shunji、Nagamatsu Ayu、Tomita Manabu、Hashida Ryuki、Nakano Dan、Niizeki Takashi、Matsuse Hiroo、Shiba Naoto、Torimura Takuji
- Journal Title
  
  Hepatology Research
  
  Volume: 50 Issue: 3 Pages: 330-341
- DOI
  10.1111/hepr.13453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09444
[Journal Article] Profiles Associated with Sarcopenia in Hepatoma Patients Underwent Transcatheter Arterial Chemoembolization: A Data‐Mining Analysis2018
- Author(s)
  Hirota K, Kawaguchi T, Hashida R, Koya S, Bekki M, Goshima N, Yoshiyama T, Otsuka T, Nozoe R, Nakano D, Shirono T, Shimose S, Iwamoto H, Niizeki T, Matsuse H, Koga H, Shiba N, Torimura T
- Journal Title
  
  Journal of Cachexia, Sarcopenia and Muscle ‐ Clinical Reports
  
  Volume: 3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09444
[Journal Article] The association between sarcopenia and decorin, an exercise‐induced myokine, in patients with liver cirrhosis: a pilot study2018
- Author(s)
  Bekki M, Hashida R, Kawaguchi T, Goshima N, Yoshiyama T, Otsuka T, Koya S, Hirota K, Matsuse H, Niizeki T, Torimura T, Shiba N
- Journal Title
  
  Journal of Cachexia, Sarcopenia and Muscle Rapid Communications
  
  Volume: 1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09444
[Journal Article] An association between dietary habits and traffic accidents in patients with chronic liver disease: A data-mining analysis.2016
- Author(s)
  Kawaguchi T, Suetsugu T, Ogata S, Imanaga M, Ishii K, Esaki N, Sugimoto M, Otsuyama J, Nagamatsu A, Taniguchi E, Itou M, Oriishi T, Iwasaki S, Miura H, Torimura T.
- Journal Title
  
  Biomed Rep.
  
  Volume: 4 Pages: 615-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461017
[Journal Article] The morbidity and associated risk factors of cancer in chronic liver disease patients with diabetes mellitus: a multicenter field survey.2015
- Author(s)
  Kawaguchi T, Kohjima M, Ichikawa T, Seike M, Ide Y, Mizuta T, Honda K, Nakao K, Nakamuta M, Sata M.
- Journal Title
  
  J Gastroenterol
  
  Volume: 50 Issue: 3 Pages: 333-341
- DOI
  10.1007/s00535-014-0968-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461017
[Journal Article] Effect of pioglitazone on outcome following curative treatment for hepatocellular carcinoma in patients with hepatitis C virus infection: A prospective study.2015
- Author(s)
  Sumie S, Kawaguchi T, Kawaguchi A, Kuromatsu R, Nakano M, Satani M, Yamada S, Okamura S, Yonezawa Y, Kakuma T, Torimura T, Sata M.
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 3 Issue: 1 Pages: 115-120
- DOI
  10.3892/mco.2014.435
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461017
[Journal Article] Effects of branched-chain amino acids and zinc-enriched nutrients on prognosticators in HCV-infected patients: a multicenter randomized controlled trial.2015
- Author(s)
  Kawaguchi T, Nagao Y, Abe K, Imazeki F, Honda K, Yamasaki K, Miyanishi K, Taniguchi E, Kakuma T, Kato J, Seike M, Yokosuka O, Ohira H, Sata M.
- Journal Title
  
  Mol Med Rep
  
  Volume: 11 Issue: 3 Pages: 2159-2166
- DOI
  10.3892/mmr.2014.2943
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461017, KAKENHI-PROJECT-25463274
[Journal Article] Exendin-4, a glucagon-like peptide-1 receptor agonist, modulates hepatic fatty acid composition and Δ-5-desaturase index in a murine model of non-alcoholic steatohepatitis.2014
- Author(s)
  Kawaguchi T, Itou M, Taniguchi E, Sata M.
- Journal Title
  
  Int J Mol Med
  
  Volume: 34 Issue: 3 Pages: 782-787
- DOI
  10.3892/ijmm.2014.1826
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461017
[Journal Article] Serum albumin level is a notable profiling factor for non-B, non-C hepatitis virus-related hepatocellular carcinoma: A data-mining analysis2014
- Author(s)
  Yamada S, Kawaguchi A, Kawaguchi T, Fukushima N, Kuromatsu R, Sumie S, Takata A, Nakano M, Satani M, Tonan T, Fujimoto K, Shima H, Kakuma T, Torimura T, Charlton MR, Sata M.
- Journal Title
  
  Hepatol Res.
  
  Volume: in press Issue: 8 Pages: 837-845
- DOI
  10.1111/hepr.12192
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461017
[Journal Article] 肝癌と素因　糖尿病と肝癌2013
- Author(s)
  川口　巧、佐田　通夫
- Journal Title
  
  The LIVER CANCER JOURNAL
  
  Volume: 5 Pages: 258-266
- Data Source
  KAKENHI-PROJECT-25461017
[Journal Article] Decreased expression of insulin and increasedexpression of pancreatic transcription factor PDX-1 in islets in patients with liver cirrhosis: a comparative investigation using human autopsy specimens.2013
- Author(s)
  Sakata M, Kawahara A, Kawaguchi T, Akiba J, Taira T, Taniguchi E, Abe M, Koga H, Kage M, Sata M.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 48 Issue: 2 Pages: 277-85
- DOI
  10.1007/s00535-012-0633-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790874
[Journal Article] Hybrid training of voluntary and electrical muscle contractions reduces steatosis, insulin resistance, and IL-6 levels in patients with NAFLD: a pilot study.2011
- Author(s)
  Kawaguchi T, Shiba N, Maeda T, Matsugaki T, Takano Y, Itou M, Sakata M, Taniguchi E, Nagata K, Sata M.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 46 Issue: 6 Pages: 746-57
- DOI
  10.1007/s00535-011-0378-x
- NAID
  10029029539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790874
[Journal Article] Hybrid training of voluntary and electrical muscle contractions decreased fasting blood glucose and serum interleukin-6 levels in elderly people: a pilot study.2011
- Author(s)
  Kawaguchi T, Shiba N, Takano Y, Maeda T, Sata M.
- Journal Title
  
  Appl Physiol Nutr Metab.
  
  Volume: 36 Issue: 2 Pages: 276-83
- DOI
  10.1139/h10-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790874
[Journal Article] Total and high molecular weight adiponectin and hepatocellular carcinoma with HCV infection.2011
- Author(s)
  Sumie S, Kawaguchi T, Kuromatsu R, Takata A, Nakano M, Satani M, Yamada S, Niizeki T, Torimura T, Sata M.
- Journal Title
  
  PLoS One.
  
  Volume: 6:e Issue: 11 Pages: 26840-26840
- DOI
  10.1371/journal.pone.0026840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790874
[Journal Article] Insulin resistance and chronic liver disease.2011
- Author(s)
  Kawaguchi T, Taniguchi E, Itou M, Sakata M, Sumie S, Sata M.
- Journal Title
  
  World J Hepatol.
  
  Volume: 3 Issue: 5 Pages: 99-107
- DOI
  10.4254/wjh.v3.i5.99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790874
[Journal Article] Quick and simple method for increasing the reduced albumin fraction in human serum albumin preparations by using stronger neo-minophagen C2011
- Author(s)
  Sakata M, Kawaguchi T, Taniguchi E, Abe M, Koga H, Sata M
- Journal Title
  
  Hepatol Res
  
  Volume: Vol.41 Issue: 11 Pages: 1120-1125
- DOI
  10.1111/j.1872-034x.2011.00863.x
- NAID
  10031144189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590865
[Journal Article] Insulin resistance and chronic liver disease2011
- Author(s)
  Kawaguchi T, et al
- Journal Title
  
  World J Hepatol
  
  Volume: 3 Pages: 99-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790874
[Journal Article] Hybrid training of voluntary and electrical muscle contractions decreased fasting blood glucose and serum interleukin-6 levels in elderly people : a pilot study.2011
- Author(s)
  Kawaguchi T, et al.
- Journal Title
  
  Applied Physiology, Nutrition, and Metabolism
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790874
[Journal Article] Branched-chain amino acids as pharmacological nutrients in chronic liver disease2011
- Author(s)
  Kawaguchi T, Izumi N, Charlton MR, Sata M
- Journal Title
  
  Hepatology
  
  Volume: Vol.54 Issue: 3 Pages: 1063-1070
- DOI
  10.1002/hep.24412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590865, KAKENHI-PROJECT-22790874
[Journal Article] Hybrid training of voluntary and electrical muscle contractions reduces steatosis, insulin resistance, and IL-6 levels in patients with NAFLD : a pilot study.2011
- Author(s)
  Kawaguchi T, et al.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: (in press)
- NAID
  10029029539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790874
[Journal Article] Pigment epithelium-derived factor inhibits lysosomal degradation of Bcl-xL and apoptosis in HepG2 cells.2010
- Author(s)
  Kawaguchi T, Yamagishi S, Itou M, Okuda K, Sumie S, Kuromatsu R, Sakata M, Abe M, Taniguchi E, Koga H, Harada M, Ueno T, Sata M.
- Journal Title
  
  Am J Pathol. 176
  
  Pages: 168-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] The Pathogenesis, Complications and Therapeutic Strategy for Hepatitis C Virus-associated Insulin Resistance in the Era of Anti-viral Treatment.2010
- Author(s)
  Kawaguchi T, et al.
- Journal Title
  
  Reviews on Recent Clinical Trials
  
  Volume: 5 Pages: 147-157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790874
[Journal Article] Association of exogenous insulin or sulphonylurea treatment with an in creased incidence of hepatoma in patients with hepatitis C virus infection2010
- Author(s)
  Kawaguchi T et al.
- Journal Title
  
  Liver Int. 30
  
  Pages: 479-486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Association of exogenous insulin or sulphonylurea treatment with an increased incidence of hepatoma in patients with hepatitis C virus infection2010
- Author(s)
  Kawaguchi T, Taniguchi E, Morita Y, Shirachi M, Tateishi I, Nagata E, Sata M
- Journal Title
  
  Liver Int
  
  Volume: Vol.30 Issue: 3 Pages: 479-486
- DOI
  10.1111/j.1478-3231.2009.02191.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590865
[Journal Article] Importance of hepatitis C virus-associated insulin resistance : therapeutic strategies for insulin sensitization.2010
- Author(s)
  Kawaguchi T, et al.
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 16 Pages: 1943-1952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590865
[Journal Article] Pigment epithelium-derived factor inhibits lysosomal degradation of Bcl-xL and apoptosis in HepG2 cells2010
- Author(s)
  Kawaguchi T et al.
- Journal Title
  
  Am J Pathol. 176
  
  Pages: 168-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Association of exogenous insulin or sulphonylurea treatment with an in creased incidence of hepatoma in patients with hepatitis C virus infection2010
- Author(s)
  Kawaguchi T, et al.
- Journal Title
  
  Liver Int. 30
  
  Pages: 479-486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590865
[Journal Article] Pigment epithelium-derived factor inhibits lysosomal degradation of Bcl-xL and apoptosis in HepG2 cells2010
- Author(s)
  Kawaguchi T, et al.
- Journal Title
  
  Am J Pathol. 176
  
  Pages: 168-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590865
[Journal Article] Association of exogenous insulin or sulphonylurea treatment with an increased incidence of hepatoma in patients with hepatitis C virus infection2010
- Author(s)
  Kawaguchi T, Taniguchi E, Morita Y, Shirachi M, Tateishi I, Nagata E, Sata M.
- Journal Title
  
  Liver Int. 30
  
  Pages: 479-486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Pigment Epithelium-derived factor inhibits lysosomal degradation of Bcl-xL and apoptosis in HepG2 cells2010
- Author(s)
  Kawaguchi T, Yamagishi S, Itou M, Okuda K, Sumie S, Kuromatsu R, Sakata M, Abe M, Taniguchi E, Koga H, Harada M, Ueno T, Sata M
- Journal Title
  
  Am J Pathol
  
  Volume: Vol.176 Issue: 1 Pages: 168-176
- DOI
  10.2353/ajpath.2010.090242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590865
[Journal Article] The pathogenesis, complications and therapeutic strategy for hepatitis C virus-associated insulin resistance in the era of anti-viral treatment.2010
- Author(s)
  Kawaguchi T, Taniguchi E, Itou M, Sumie S, Yamagishi S, Sata M.
- Journal Title
  
  Rev Recent Clin Trials.
  
  Volume: 5 Pages: 147-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790874
[Journal Article] Importance of hepatitis C virus-associated insulin resistance : therapeutic strategies for insulin sensitization2010
- Author(s)
  Kawaguchi T, Sata M
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: Vol.16 Issue: 16 Pages: 1943-1952
- DOI
  10.3748/wjg.v16.i16.1943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590865
[Journal Article] Oxidized albumin is associated with water retention and severity of disease in patients with chronic liver diseases2010
- Author(s)
  Sakata M, Kawaguchi T, Taniguchi E, Nakayama A, Ishizaki S, Sonaka I, Nakamura T, Itou M, Oriishi T, Abe M, Yanagimoto C, Koga H, Sata M
- Journal Title
  
  e-SPEN, the European e-Journal of Clinical Nutrition and Metabolism
  
  Volume: Vol.5 Issue: 6 Pages: 247-253
- DOI
  10.1016/j.eclnm.2010.09.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590865
[Journal Article] Redox state of albumin is not associated with colloid osmotic pressure2010
- Author(s)
  Sakata M, Kawaguchi T, Taniguchi E, Nakayama A, Ishizaki S, Sonaka I, Maganuma M, Nakamura T, Itou M, Oriishi T, Abe M, Yanagimoto C, Koga H, Harada M, Sakamoto T, Oda S, Sata M
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: Vol.3 Issue: 4 Pages: 685-687
- DOI
  10.3892/mmr_00000317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590865
[Journal Article] Thrombocytopenia, an important interfering factor of antiviral therapy and hepatocellular carcinoma treatment for chronic liver diseases2009
- Author(s)
  Kawaguchi T, et al.
- Journal Title
  
  Kurume Med J. 56
  
  Pages: 9-15
- NAID
  130000168343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590865
[Journal Article] Thrombocytopenia, an Important Interfering Factor of Antiviral Therapy and Hepatocellular Carcinoma Treatment for Chronic Liver Diseases2009
- Author(s)
  Kawaguchi T, Kuromatsu R, Ide T, Taniguchi E, Itou M, Sakata M, Abe M, Sumie S, Sata M
- Journal Title
  
  The Kurume Medical Journal
  
  Volume: 56 Issue: 1/2 Pages: 9-15
- DOI
  10.2739/kurumemedj.56.9
- NAID
  130000168343
- ISSN
  0023-5679, 1881-2090
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590865
[Journal Article] Branched-chain amino acids and pigment epithelium-derived factor: novel therapeutic agents for hepatitis c virus-associated insulin resistance.2009
- Author(s)
  Kawaguchi T, Yamagishi S, Sata M.
- Journal Title
  
  Curr Med Chem. 16
  
  Pages: 4843-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Thrombocytopenia, an important interfering factor of antiviral therapy and hepatocellular carcinoma treatment for chronic liver diseases2009
- Author(s)
  Kawaguchi T et al.
- Journal Title
  
  Kurume Med J. 56
  
  Pages: 9-15
- NAID
  130000168343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Thrombocytopenia, an important interfering factor of antiviral therapy and hepatocellular carcinoma treatment for chronic liver diseases.2009
- Author(s)
  Kawaguchi T, Kurumatsu R, Ide T, Taniguchi E, Itou M, Sakata M, Abe M, Sumie S, Sata M
- Journal Title
  
  Kurume Med J. 56
  
  Pages: 9-15
- NAID
  130000168343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease.2008
- Author(s)
  Kawaguchi T.
- Journal Title
  
  Int J Mol Med 22
  
  Pages: 105-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592213
[Journal Article] HCV あるいはHBV 感染者における歯科治療時の自己申告調査2008
- Author(s)
  長尾由実子, 川口巧, 井出達也, 佐田通夫
- Journal Title
  
  感染症誌 82
  
  Pages: 213-219
- NAID
  10021928885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592213
[Journal Article] Supplement improves nutrition and stresses caused by examination-associated fasting in patients with liver cirrhosis.2008
- Author(s)
  Kawaguchi T, Taniguchi E, Itou M, Mutou M, Ibi R, Shiraishi S, Okada T, Uchida Y, Otsuka M, Tonan T, Fujimoto K, Oriishi T, Tanaka S, Takakura M, Sata M
- Journal Title
  
  Hepatol Res. 38
  
  Pages: 1178-85
- NAID
  10023920545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Altered expression of glucagon-like peptide-I and dipeptidyI peptidase IV in patients with HCV-related glucose intolerance.2008
- Author(s)
  Itou M, Kawaguchi T, Taniguchi E, et. al.
- Journal Title
  
  J Gastroenterol Hepatol. 23
  
  Pages: 244-251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Body cell mass is a useful parameter for assessing malnutrition and severity of disease in non-ascitic cirrhotic patients with hepatocellular carcinoma or esophageal varices.2008
- Author(s)
  Kawaguchi T, Taniguchi E, Itou M, Ibi R, Okada T, Mutou M, Shiraishi S, Uchida Y, Otsuka M, Umeki Y, Oriishi T, Hayabuchi H, Tanaka S, Takakura M, Sata M
- Journal Title
  
  Int J Mol Med. 22
  
  Pages: 589-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease.2008
- Author(s)
  Kawaguchi T, Nagao Y, Matsuoka H, Ide T, Sata M
- Journal Title
  
  Int J Mol Med. 22
  
  Pages: 105-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Body cell mass is a useful parameter for assessing malnutrition and severity of disease in non-ascitic cirrhotic patients with hepatocellular car cinoma or esophageal varices2008
- Author(s)
  Kawaguchi T, et.al.
- Journal Title
  
  Int J Mol Med 22
  
  Pages: 589-594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease2008
- Author(s)
  Kawaguchi T, et.al.
- Journal Title
  
  Int J Mol Med 22
  
  Pages: 105-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Altered expression of glucagon-like peptide-1 and dipeptidyl peptidase IV in patients with HCV-related glucose intolerance.2008
- Author(s)
  Itou M, Kawaguchi T, Taniguchi E, Sumie S, Oriishi T, Mitsuyama K, Tsuruta O, Ueno T, Sata M
- Journal Title
  
  J Gastroenterol Hepatol. 23
  
  Pages: 244-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] Branched-chain amino acids-enriched supplement improves insulin resistance and beta-cell function in male patients with chronic viral liver dieases2008
- Author(s)
  Kawaguchi T.
- Journal Title
  
  J Int Mol.Med (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592213
[Journal Article] Supplement improves nutrition and stresses caused by examination-associated fasting in patients with liver cirrhosis2008
- Author(s)
  Kawaguchi T, et.al.
- Journal Title
  
  Hepatol Res 38
  
  Pages: 1178-1185
- NAID
  10023920545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790643
[Journal Article] HBV and HCV infection in Japanese dental care workers.2008
- Author(s)
  Nagao Y , Matsuoka H, Kawaguchi T, Ide T, Sata M
- Journal Title
  
  Int J Mol Med 21
  
  Pages: 791-799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592213
[Journal Article] Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease.2008
- Author(s)
  Kawaguchi T, Nagao Y , Matsuoka H, Ide T, Sata M
- Journal Title
  
  Int J Mol Med 22
  
  Pages: 105-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592213
[Journal Article] Clearance of HCV Improves Insulin Resistance, Beta-Cell Function, and Hepatic Expression of Insulin Receptor Substrate 1 and 2.2007
- Author(s)
  Kawaguchi T.
- Journal Title
  
  Am J Gastrol. (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590648
[Journal Article] Clearance of HCV Improves Insulin Resistance, Beta-Cell Function, and Hepatic Expression of Insulin Receptor Substrate 1 and 2.2007
- Author(s)
  Kawaguchi T et al.
- Journal Title
  
  Am J Gastroenterol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590648
[Journal Article] Branched-chain amino acids improve insulin resistance in patients with hepatitis C virus-related liver disease:report of two cases2007
- Author(s)
  Kawaguchi T.
- Journal Title
  
  Liver Int 9
  
  Pages: 1287-1292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592213
[Journal Article] Clearance of HCV Improves Insulin Resistance, Beta-Cell Function, and Hepatic Expression of Insulin Receptor Substrate 1 and 2.2007
- Author(s)
  Kawaguchi T.
- Journal Title
  
  Am J Gatrol. 102・3
  
  Pages: 570-576
- Data Source
  KAKENHI-PROJECT-16590648
[Journal Article] Clearance of HCV improves insulin resistance, Beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2.2007
- Author(s)
  Kawaguchi T.
- Journal Title
  
  Am J Gastroenterol 102・3
  
  Pages: 570-576
- Data Source
  KAKENHI-PROJECT-18592213
[Journal Article] Clearance of HCV improves insulin resistance, Beta-cell function, and hepatic expression of insulin receptor substrate 1 and 22007
- Author(s)
  Kawaguchi T, Ide T, Taniguchi E, Hirano E, Itou M, Sumie S, Nagao Y , Yanagimoto C, Hanada S, Koga H, Sata M
- Journal Title
  
  Am J Gastroenterol 102
  
  Pages: 570-576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592213
[Journal Article] Branched-chain amino acids improve insulin resistance in patients with hepatitis C virus-related liver disease: report of two cases.2007
- Author(s)
  Kawaguchi T, Taniguchi E, Itou M, Sumie S, Oriishi T, Matsuoka H, Nagao Y , Sata M
- Journal Title
  
  Liver Int 50
  
  Pages: 1287-1292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592213
[Journal Article] Clearance of HCV improves insulin resistance,Beta-cell function,and hepatic expression of insulin receptor substrate 1 and 22007
- Author(s)
  Kawaguchi T.
- Journal Title
  
  Am J Gastroenterol 102
  
  Pages: 570-576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592213
[Journal Article] Appearance-specific satiety increases appetite and quality of life in patients with metastatic liver tumor : a case report.2006
- Author(s)
  Kawaguchi T et al.
- Journal Title
  
  Kurume Med J. 53
  
  Pages: 41-6
- NAID
  130000097829
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590648
[Journal Article] Appearance-specific satiety increases appetite and quality of life in patients with metastatic liver tumor : a case report.2006
- Author(s)
  Kawaguchi T.
- Journal Title
  
  Kurume Med J. 53
  
  Pages: 41-46
- NAID
  130000097829
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590648
[Journal Article] Branched-chain amino Acid supplementation complements conventional treatment for spontaneous bacterial peritonitis.2006
- Author(s)
  Taniguchi E, Kawaguchi T, Shimada M, Kuwahara R, Nagao Y , Otsuka M, Iwasaki S, Matsuda T, Ibi R, Shiraishi S, Itou M, Oriishi T, Kumashiro R, Tanaka S, Saruwatari Y, Sata M
- Journal Title
  
  Digest Dis Sci 51
  
  Pages: 1057-1060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592213
[Journal Article] Causal relationship between hepatitis C virus core and the development of type 2 diabetes mellitus in a hepatitis C virus hyperendemic area : a pilot study2005
- Author(s)
  Kawaguchi T
- Journal Title
  
  Int J Mol Med 16-1
  
  Pages: 109-114
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590963
[Journal Article] Causal relationship between hepatitis C virus core and the development of type 2 diabetes mellitus in a hepatitis C virus hyperendemic area : a pilot study.2005
- Author(s)
  Kawaguchi T et al.
- Journal Title
  
  Int J Mol Med. 16
  
  Pages: 109-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590648
[Journal Article] Causal relationship between hepatitis C virus core and the development of type 2 diabetes mellitus in a hepatitis C virus hyperendemic area : a pilot study.2005
- Author(s)
  Kawaguchi T
- Journal Title
  
  Int J Mol Med 16・1
  
  Pages: 109-114
- Data Source
  KAKENHI-PROJECT-16590648
[Journal Article] Causal relationship between hepatitis C virus core and the development of type 2 diabetes mellitus in a hepatitis C virus hyperendemic area : a pilot study.2005
- Author(s)
  Kawaguchi T
- Journal Title
  
  Int J Mol Med 16・1
  
  Pages: 109-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590963
[Journal Article] Causal relationship between hepatitis C virus core and the development of type 2 diabetes mellitus in a hepatitis C virus hyperendemic area : a pilot study.2005
- Author(s)
  Kawaguchi T.
- Journal Title
  
  Int J Mol Med. 16
  
  Pages: 109-114
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590648
[Journal Article] Hepatitis C virus down-regulates insulin receptor substrate 1 and 2 through up-regulation of suppressor of cytokine signaling 3.2004
- Author(s)
  Kawaguchi T
- Journal Title
  
  Am J Pathol. 165・5
  
  Pages: 1499-1508
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590963
[Journal Article] Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3.2004
- Author(s)
  Kawaguchi T et al.
- Journal Title
  
  Am J Pathol. 165
  
  Pages: 1499-508
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590648
[Journal Article] Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 32004
- Author(s)
  Takumi Kawaguchi, Takafumi Yoshida, Masaru Harada, Takao Hisamoto, Yumiko Nagao, Tatsuya Ide, Eitaro Taniguchi, Hiroto Kumemura, Shinichiro Harada, Michiko Maeyama, Shinji Baba, Hironori Koga, Ryukichi Kumashiro, Takato Ueno, Hisanobu Ogata, Akihiko Yoshi
- Journal Title
  
  Am J Pathol 165
  
  Pages: 1499-1508
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590650
[Journal Article] Hepatitis C virus down-regulates insulin receptor substrate 1 and 2 through up-regulation of suppressor of cytokine signaling 3.2004
- Author(s)
  Kawaguchi T
- Journal Title
  
  Am J Pathol 165・5
  
  Pages: 1499-1508
- Data Source
  KAKENHI-PROJECT-16590648
[Journal Article] Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 32004
- Author(s)
  Kawaguchi T
- Journal Title
  
  Am J Pathol 165-5
  
  Pages: 1499-1508
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590963
[Journal Article] Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 32004
- Author(s)
  Takumi Kawaguchi, et al.
- Journal Title
  
  American Journal of Pathology 165・5
  
  Pages: 1499-1508
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590650
[Journal Article] Hepatitis C virus down-regulates insulin receptor substrate 1 and 2 through up-regulation of suppressor of cytokine signaling 3.2004
- Author(s)
  Kawaguchi T
- Journal Title
  
  Am J Pathol 165・5
  
  Pages: 1499-1508
- Data Source
  KAKENHI-PROJECT-15590963
[Journal Article] Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3.2004
- Author(s)
  Kawaguchi T
- Journal Title
  
  Am J Pathol. 165
  
  Pages: 1499-1508
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590648
[Presentation] がんリハビリテーションが肝癌患者の予後におよぼす影響2022
- Author(s)
  川口　巧、橋田竜騎、中野　暖、堤翼、松瀬博夫、平岡弘二
- Organizer
  第29回日本門脈圧亢進症学会総会
- Data Source
  KAKENHI-PROJECT-20K08395
[Presentation] An Impact of Albumin-Bilirubin (ALBI) Score on Pulmonary Arterial Pressure in Patients with Chronic Liver Disease with Porto-pulmonary Hypertension (PoPH): A Data-mining Analysis2021
- Author(s)
  Takumi Kawaguchi, Akihiro Honda, Yoichi Sugiyama, Dan Nakano, Tsubsa Tsutsumi, Nobuhiro Tahara, Takuji Torimura, Yoshihiro Fukumoto
- Organizer
  The Liver Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08395
[Presentation] マイオカインdecorinが肝がん患者のサルコペニアと予後におよぼす影響2021
- Author(s)
  中野　暖、川口　巧、鳥村　拓司
- Organizer
  第25回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-20K08395
[Presentation] 運動療法が肝硬変患者のフレイルにおよぼす影響2020
- Author(s)
  堤　翼，土橋　仁，川口　巧
- Organizer
  第27回日本門脈圧亢進症学会総会
- Data Source
  KAKENHI-PROJECT-20K08395
[Presentation] NAFLD/NASHにおける運動療法のSystematic Reviewとハイブリッドトレーニングの有効性2020
- Author(s)
  川口　巧
- Organizer
  第52回日本動脈硬化学会総会
- Data Source
  KAKENHI-PROJECT-20K08395
[Presentation] The Liver Frailty Index was Related to Hypoalbuminemia with Hyperglycemia, but not Muscle Mass, in Cirrhotic Patients with Hepatocellular Carcinoma: A Data-mining Analysis2019
- Author(s)
  Kawaguchi T, Hirota K, Koya S, Hashida R, Nakano D, Shirono T, Shimose S, Iwamoto H, Niizeki T, Matsuse H, Shiba N and Torimura T
- Organizer
  The 70th Annual Meeting of the American Association for the Study of Liver Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09444
[Presentation] がんリハビリテーションが進行肝癌患者のサルコペニアと予後におよぼす影響2019
- Author(s)
  川口　巧、橋田竜騎、鳥村拓司
- Organizer
  第23回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-17K09444
[Presentation] 運動療法が肝がん患者のサルコペニアにおよぼす影響2018
- Author(s)
  川口　巧、中野　暖、橋田　竜騎、城野　智毅、下瀬　茂男、岩本　英希、相野　一、新関　敬、古賀　浩徳、志波　直人、鳥村　拓司
- Organizer
  第104回　日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17K09444
[Presentation] In-hospital Exercise Prevented Sarcopenia in Hepatoma Patients with Chronic Liver Disease Who Underwent Transcatheter Arterial Chemoembolization2018
- Author(s)
  Kawaguchi T, Koya S, Hashida R, Hirota K, Bekki M, Goshima N, Yoshiyama T, Otsuka T, Nozoe R, Nagamatsu A, Nakano D, Shirono T, Shimose S, Iwamoto H, Niizeki T, Matsuse H, Koga H, Shiba N, Torimura T
- Organizer
  The Liver Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09444
[Presentation] 肝疾患におけるサルコペニア判定基準の比較と運動療法の効果2018
- Author(s)
  川口　巧、中野　暖、鳥村　拓司
- Organizer
  第54回　日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17K09444
[Presentation] Decorin, a Newly Identified Exercise-induced Myokine, was Associated with Sarcopenia in Patients with Liver Cirrhosis2017
- Author(s)
  Ryuki Hashida, Takumi Kawaguchi, Shunji Koya, Keisuke Hirota, Goshima, Otsuka, Masafumi Bekki, Hiroo Matsuse, Jun Hayashi, Naoto Shiba, Takuji Torimura
- Organizer
  The Liver Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09444
[Presentation] 有酸素運動とレジスタンス運動によるNAFLD改善効果の比較検討2017
- Author(s)
  川口　巧、橋田　竜騎、鳥村　拓司
- Organizer
  第103回　日本消化器病学会
- Data Source
  KAKENHI-PROJECT-17K09444
[Presentation] 運動療法が肝硬変患者のサルコペニアにおよぼす影響2017
- Author(s)
  川口　巧、志波　直人、鳥村　拓司
- Organizer
  Japan Digestive Disease Week 2017
- Data Source
  KAKENHI-PROJECT-17K09444
[Presentation] Ectopic Fat Deposition in Skeletal Muscle was Associated with Diabetes Mellitus in Patients with Non-Alcoholic Fatty Liver Disease: A MRI-proton Density Fat-fraction Analysis2017
- Author(s)
  Takumi Kawaguchi, Tatsuyuki Tonan, Kiminori Fujimoto, Toshi Abe, Takuji Torimura
- Organizer
  AMERICAN ASSOCIATION FOR THE STUDY LIVER DISEASES (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461809
[Presentation] 肝発癌抑制を目指した耐糖能異常へのアプローチ：C型肝炎におけるインクレチン動態と肝細胞糖取り込みにおけるGLP-1シグナル伝達経路2012
- Author(s)
  川口　巧
- Organizer
  第48回日本肝臓学会
- Place of Presentation
  金沢市, 石川県, 日本
- Data Source
  KAKENHI-PROJECT-22790874
[Presentation] Sata M. GLP-1R agonist increased glucose uptake and inhibited GSK3β phosphorylation through the AMPK signaling pathways in human hepatocytes.2012
- Author(s)
  Itou M, Kawaguchi T, Sakata M, Taniguchi E, Sumie S, Oriishi T, Mitsuyama K, Torimura T, Tsuruta O
- Organizer
  Digestive Disease Week2012.
- Place of Presentation
  San Diego, California, USA.
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-22790874
[Presentation] 肝発癌抑制を目指した耐糖能異常へのアプローチ:C型肝炎におけるインクレチン動態と肝細胞糖取り込みにおけるGLP-1シグナル伝達経路.2012
- Author(s)
  川口巧,伊藤実,佐田通夫.
- Organizer
  第48回日本肝臓学会
- Place of Presentation
  金沢市,石川県
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-22790874
[Presentation] 慢性肝疾患患者におけるBCAA・亜鉛含有食品のインスリン抵抗性改善効果2011
- Author(s)
  川口巧, ら
- Organizer
  第15回日本肝臓学会大会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-22790874
[Presentation] HCV関連肝細胞癌と糖尿病治療薬の関連2011
- Author(s)
  川口巧, ら
- Organizer
  第15回日本肝臓学会大会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22790874
[Presentation] HCV関連肝細胞癌と糖尿病治療薬の関連.2011
- Author(s)
  川口巧,谷口英太郎,佐田通夫.
- Organizer
  第15回日本肝臓学会大会.
- Place of Presentation
  福岡市,福岡県.
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-22790874
[Presentation] 慢性肝疾患患者におけるBCAA・亜鉛含有食品のインスリン抵抗性改善効果.2011
- Author(s)
  川口巧,長尾由実子,井出達也,佐田通夫.
- Organizer
  第15回日本肝臓学会大会.
- Place of Presentation
  福岡市,福岡県.
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-22790874
[Presentation] Hybrid-training of voluntary and electrical muscle contractions improves nonalcoholic fatty liver disease and reduces insulin resistance and interleukin-6 levels.2010
- Author(s)
  Kawaguchi T, Shiba N, Maeda T, Matsugaki T, Takano Y, Itou M, Sakata M, Taniguchi E, Nagata K, Sata M.
- Organizer
  The 61st Annual Meeting of the American Association for the Study of the Liver Disease.
- Place of Presentation
  Boston, Massachusetts, USA.
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22790874
[Presentation] Hybrid-training of voluntary and electrical muscle contractions improves nonalcoholic fatty liver disease and reduces insulin resistance and interleukin-6 levels.2010
- Author(s)
  Kawaguchi T, et al.
- Organizer
  The 61st Annual Meeting of the American Association for the Study of the Liver Disease
- Place of Presentation
  Boston, USA
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22790874
[Presentation] Pigment Epithelium-Derived Factor Suppresses Apoptosis through Lysosomal Degradation of Bcl-xL in HepG2 cells2009
- Author(s)
  Kawaguchi T, et al.
- Organizer
  The 60^<th> Annual Meeting of the Association for the Study of Liver Disease
- Place of Presentation
  Boston, Massachusetts, USA
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-21590865
[Presentation] Use of exogenous insulin or sulfonylureas is a potential risk factor for heptocellular carcinoma in hepatitis C patients with diabetes mellitus.2009
- Author(s)
  Kawaguchi T, et al.
- Organizer
  44th Annual Meeting of the European Association for the Study of the Liver.
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2009-04-02
- Data Source
  KAKENHI-PROJECT-19790643
[Presentation] Pigment Epithelium-Derived Factor Suppresses Apoptosis through Lysosomal2009
- Author(s)
  Kawaguchi T, et al
- Organizer
  Degradation of Bcl-xL in HepG2 cells The 60^<th> Annual Meeting of the Association for the Study of Liver Disease
- Place of Presentation
  Boston Massachusetts, USA
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-21590865
[Presentation] Pigment Epithelium-Derived Factor Suppresses Apoptosis through Lysosomal Degradation of Bcl-xL in HepG2 cells.2009
- Author(s)
  Kawaguchi T, et al.
- Organizer
  The 60th Annual Meeting of the Association for the Study of Liver Disease
- Place of Presentation
  Boston, Massachusetts, USA
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-19790643
[Presentation] USE OF EXOGENOUS INSULIN OR SULFONYLUREA ASSOCIATED WITH AN INCREASED INCIDENCE OF HEPATOCELLULAR CARCINOMA IN PATIENTS WITH HEPATITIS C VIRUS INFECTION2009
- Author(s)
  Kawaguchi T et al.
- Organizer
  44^<th> Annual Meeting of the European Association for the Study of the Liver
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2009-04-02
- Data Source
  KAKENHI-PROJECT-19790643
[Presentation] Use of exogenous insulin or sulfonylureas is a potential risk factor for heptocellular carcinoma in hepatitis C patients with diabetes mellitus2008
- Author(s)
  Taniguchi E, Kawaguchi T, Morita Y, Sata M
- Organizer
  American Association for the Study of Liver Diseases's 59th Annual Meeting
- Place of Presentation
  SanFrancisco, USA
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19790643
[Presentation] 体組成計を用いた肝疾患の重傷度評価2007
- Author(s)
  川口巧, ら
- Organizer
  第11回日本肝臓学会大会
- Place of Presentation
  神戸
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-19790643
[Presentation] 体組成計を用いた肝疾患の重傷度評価2007
- Author(s)
  川口, 巧
- Organizer
  第11回日本肝蔵学会大会
- Place of Presentation
  神戸
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-19790643
[Presentation] 糖尿病を合併する肝疾患患者のがん有病率とがん関連因子
- Author(s)
  川口巧、國府島庸之、市川辰樹、清家正隆、井手康史、水田敏彦、本田浩一、中尾一彦、中牟田誠、佐田通夫
- Organizer
  第17回　日本肝臓学会大会
- Place of Presentation
  グランドプリンスホテル新高輪（東京都港区）
- Data Source
  KAKENHI-PROJECT-25461017

1. SATA Michio (10162398)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
2. TANIGUCHI Eitaro (50341318)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. NAGAO Yumiko (90227992)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. HARADA Masaru (00241175)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KOGA Hironori (90268855)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 橋田竜騎 (40754841)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
7. 中野暖 (40723987)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
8. Kawaguchi Atsushi (60389319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
9. Yamada Shingo (50425188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. YOSHIDA Takafumi (30368899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. UENO Takato (70176618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. TORIYAMA Takuji (60197986)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HASHIMOTO Osamu (50289427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAKAMURA Toru (30341332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Tonan Tatsuyuki (40268892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 藤本公則 (00199366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 安陪等思 (90167940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 堤翼 (60624103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kawaguchi Takumi 川口 巧

KAWAGUCHI Takumi 川口 巧

Research Projects

Research Products

Co-Researchers

レジスタンス運動誘発マイオカインによる肝発がん抑制効果の機序Principal Investigator

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Effects of myokine decorin on NASH-related hepatocellular carichomaPrincipal Investigator

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Effects of exercise-induced hormon "irisin" on NASH-related hepatomaPrincipal Investigator

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Imaging Biomarker of 3T-MRI in NASH

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Identification of new risk factor for nonB, nonC hepatocellular carcinoma: Global analysis using GWAS and data-mining analysis

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The cytobiological impact of insulin resistance on BMPs-related epithelial-mesenchymal transition of hepatocellular carcinomaPrincipal Investigator

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Effects of redox state of albumin on hepatocarcinogenesis

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The impact of hyperinsulinemia and tuberin in the development of hepatocellular carcinomaPrincipal Investigator

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Relationship between lichen planus, a precancerous lesion, and insulin resistance induced by hepatitis C virus

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MOLECULAR MECHANISMS FOR THE DEVELOPMENT OF HEPATITIS C VIRUS-RELATED INSULIN RESISTANCE

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Research for usefulness of intestinal peptide, PYY_<3-36> for therapeutic agents of fatty liver and NASH

Principal Investigator

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BIOLOGICAL ROLES OF NEW TRANSCRIPTION FACTOR FOR GLUCOSE METABOLISM(ChREBP) IN PANCREATIC ISLET CELLSPrincipal Investigator

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[Journal Article] Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma in the era of chemo-diversity2023

Author(s)

Journal Title

Kawaguchi Takumi 川口巧

KAWAGUCHI Takumi 川口巧