Ota Kazuhisa 太田一寿

… Alternative Names

OTA Kazuhisa 太田一寿

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Researcher Number	00322727
Other IDs
Affiliation (Current)	2025: 長崎国際大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2013 – 2014: 長崎国際大学, 薬学部, 准教授 2011 – 2013: 東京大学, 理学(系)研究科(研究院), 助教 2009 – 2010: The University of Tokyo, 大学院・理学系研究科, 助教 2006: 東京大学, 大学院新領域創成科学研究科, 助手 2004 – 2005: 東京大学, 大学院・新領域創成科学研究科, 助手 2004: THE UNIVERSITY OF TOKYO, GRADUATE SCHOOL OF FRONTIER SCIENCES, RESEARCH ASSOCIATE, 大学院新領域創成科学研究科, 助手 2000 – 2003: 金沢大学, がん研究所, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / General medical chemistry / Genome biology / Applied genomics Except Principal Investigator Biological Sciences / General medical chemistry / System genome science / Genome biology
Keywords	Principal Investigator 出芽酵母 / ユビキチン / プロテオミクス / 質量分析 / CpGアイランド / 質量分析計 / 脱ユビキチン化酵素 / 翻訳後修飾 / 質量分析器 / MS … More / ユビキチン化 / M.SssI / 1ハイブリッド / ヒト21番染色体 / McrBC / HpaII / メチル化 / 酵母 / インプリント / 2ハイブリッド … More Except Principal Investigator DNAメチル化 / 相互作用ドメイン / 酵母2ハイブリッド法 / GIドメイン / 2ハイブリッド法 / ユビキチン / PB1ドメイン / TAPタグ / 蛋白質相互作用 / FULL LENGTH cDNA / DNA METHYLATION / MASS SPECTROMETRY / UBIQUITIN / TAP TAG / PB1 DOMAIN / YEAST 2-HYBRID SYSTEM / PROTEIN-PROTEIN INTERACTION / 出芽酵母 / 転写開始点 / 蛋白質核酸相互作用 / 1ハイブリッド法 / 蛋白質DNA相互作用 / ユビキチン化 / 質量分析法 / 蛋白質間相互作用 / 全長cDNA / 質量分析 / タンパク質間相互作用 / translational control / nutritional stress response / GCN pathway / TOR signaling / eIF2α / GCN2 / ラパマシン / TOR / 翻訳制御 / 栄養ストレス応答 / GCN経路 / TORシグナリング / SAM / レトロトランスポゾン / ミトコンドリア / ヒストンメチル化 / 適応 / トランスオミクス / 人工遺伝子回路 / 1ハイブリッドシステム / 脱メチル化 / TET2 / TET1 / 次世代シーケンサ / ヒドロキシメチル化 / ヒドロキシメチルシトシン / エピジェネティクス / ５ヒドロキシメチルシトシン / CpGアイランド / インプリンティング / PXドメイン / PBIドメイン / プロテオーム / 保証付き逆2ハイブリッド法 / SH3ドメイン / MS / LC / PAP法 Less

Transomic analysis of adaptation induced by a synthetic gene circuit
- Principal Investigator
  
  ITO Takashi
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  System genome science
- Research Institution
  Kyushu University
Analysis of 5-hydroxymethylcytosine: genome-wide mapping and screening for binding proteins
- Principal Investigator
  
  ITO Takashi
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genome biology
- Research Institution
  Kyushu University
  The University of Tokyo
Systematic identification and classification of polyubiquitinated proteins with specific chain linkage patterns.Principal Investigator
- Principal Investigator
  
  OTA kazuhisa
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genome biology
- Research Institution
  Nagasaki International University
  The University of Tokyo
A systematic search for potential substrates of deubiquitinase with quantitative proteomicsPrincipal Investigator
- Principal Investigator
  
  OTA Kazuhisa
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied genomics
- Research Institution
  The University of Tokyo
ポリユビキチン化蛋白質の定量的プロファイリングの試みPrincipal Investigator
- Principal Investigator
  
  太田一寿
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo
ポリユビキチン化基質蛋白質の網羅的同定Principal Investigator
- Principal Investigator
  
  太田一寿
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo
  Kanazawa University
SYSTEMATIC COLLECTION OF BASIS INFORMATION FOR PROTEIN INTERACTION PREDICTION
- Principal Investigator
  
  ITO Takashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  THE UNIVERSITY OF TOKYO
ヒトゲノム情報に基づく系統的メチル化解析によるがん関連インプリント遺伝子の検索Principal Investigator
- Principal Investigator
  
  太田一寿
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
A NOVEL MECHANISM FOR TRANSLATION CONTROL REGULATION OF GCN PATHWAY BY TOR AND GI DOMAIN PROTEINS
- Principal Investigator
  
  ITO Takashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  THE UNIVERSITY OF TOKYO
  Kanazawa University
構造生物学研究へのゲノムリソース活用促進技術の開発Principal Investigator
- Principal Investigator
  
  太田一寿
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
ゲノム的アプローチによるがん関連遺伝子としてのインプリント遺伝子の探索Principal Investigator
- Principal Investigator
  
  太田一寿
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
蛋白質間相互作用ドメインへのゲノム的アプローチ
- Principal Investigator
  
  ITO Takashi
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
蛋白質―蛋白質相互作用情報の系統的解析
- Principal Investigator
  
  伊藤隆司
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
がん関連遺伝子候補としてのインプリント遺伝子の網羅的単離
- Principal Investigator
  
  伊藤隆司
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University

All 2014 2012 2011 2010 2009 2005 2004 2003 2002 2001 2000

All Journal Article Presentation

[Journal Article] Detecting protein-DNA interactions using a modified yeast one-hybrid system2014
- Author(s)
  Kazuhisa Ota, Shu-Ying Feng, Takashi Ito
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1164 Pages: 39-50
- DOI
  10.1007/978-1-4939-0805-9_5
- ISBN
  9781493908042, 9781493908059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310130, KAKENHI-PROJECT-23510233
[Journal Article] A yeast one-hybrid system to screen for methylated DNA-binding proteins2010
- Author(s)
  Feng SY, Ota K, Ito T.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21710200
[Journal Article] A yeast one-hybrid system to screen for methylated DNA-binding proteins.2010
- Author(s)
  Feng SY., Ota K., Ito T.
- Journal Title
  
  Nucleic Acids Res.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21710200
[Journal Article] Remodeling of the SCF complex-mediated ubiquitination system by compositional alteration of incorporated F-box proteins2010
- Author(s)
  Kato, M., Kito, K., Ota, K.Ito, T.
- Journal Title
  
  Proteomics 10
  
  Pages: 115-123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21710200
[Journal Article] Remodeling of the SCF Complex-mediated Ubiquitination System by Compositional2009
- Author(s)
  Kato M., Kito K., Ota K., Ito T.
- Journal Title
  
  Alteration of Incorporated F-box Proteins Proteomics
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21710200
[Journal Article] Circular permutation of ligand-binding module improves dynamic range of genetically encoded FRET-based nanosensor.2009
- Author(s)
  Okada S., Ota K., Ito T.
- Journal Title
  
  Protein Sci.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21710200
[Journal Article] The yeast eIF4E-associated protein Eap 1p attenuates GCN4 translation upon TOR inactivation2005
- Author(s)
  Matsuo, R., Kubota, H., Obata, T., Kito, K., Ota, K., Kitazono, T., Ibayashi, S., Sasaki, T., Iida, M., Ito, T.
- Journal Title
  
  FEBS Lett. 579
  
  Pages: 2433-2438
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] Transcriptomic and proteomic analysis of a 14-3-3 gene-deficient yeast2004
- Author(s)
  Ichimura, T., Kubota, H., Goma, T., Mizushima, N., Ohsumi, Y., Iwago, M., Kakiuchi, K., Shekhar, H.U., Shinkawa, T., Taoka, M., Ito, T., Isobe, T.
- Journal Title
  
  Biochemistry 43
  
  Pages: 6149-6158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] Analysis of gene network regulating yeast multidrug resistance by artificial activation of transcription factors : involvement of Pdr3 in salt tolerance.2004
- Author(s)
  Onda M, Ota K, Chiba T, Sakaki Y, Ito T.
- Journal Title
  
  Gene. 332
  
  Pages: 51-59
- Data Source
  KAKENHI-PROJECT-15790148
[Journal Article] A yeast one-hybrid system to detect methylation-dependent DNA-protein interactions2004
- Author(s)
  Feng, S.-Y., Ota, K., Yamada, Y., Sawabu, N., Ito, T.
- Journal Title
  
  Biochem.Biophys.Res.Commun 313
  
  Pages: 922-925
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] Analysis of gene network regulating yeast multidrug resistance by artificial activation of transcription factors : involvement of Pdr3 in salt resistance2004
- Author(s)
  Onda, M., Ota, K., Chiba, T., Sakaki, Y., Ito, T.
- Journal Title
  
  Gene 332
  
  Pages: 51-59
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] Analysis of gene network regulating yeast multidrug resistance by artificial activation of transcription factors : involvement of Pdr3 in salt resistance2004
- Author(s)
  Dnda, M., Ota, K., Chiba, T., Sakaki, Y., Ito.T.
- Journal Title
  
  Gene 332
  
  Pages: 51-59
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] A yeast one-hybrid system to detect methylation-dependent DNA-protein interactions.2004
- Author(s)
  Feng SY, Ota K, Yamada Y, Sawabu N, Ito T.
- Journal Title
  
  Biochem Biophys Res Commun. 313(4)
  
  Pages: 922-925
- Data Source
  KAKENHI-PROJECT-15790148
[Journal Article] A yeast one-hybrid system to detect methylation-dependent DNA-protein interactions2004
- Author(s)
  Feng, S.-Y., Ota, K., Yamada, Y., Sawabu, N., Ito, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 313
  
  Pages: 922-925
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2α kinase GCN22003
- Author(s)
  Kubota, H., Obata, T., Ota, K., Sasaki, T., Ito, T.
- Journal Title
  
  J. Biol. Chem. 278
  
  Pages: 20457-20460
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] Molecular recognition in dimerization between PB1 domains2003
- Author(s)
  Noda, Y., Kohjima, M., Izaki, T., Ota, K., Yoshinaga, S., Inagaki, F., Ito, T., Sumimoto, H.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 43516-43524
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2a kinase GCN22003
- Author(s)
  Kubota, H., Obata, T., Ota, K., Sasaki, T., Ito, T.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 20457-20460
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] Roles for the two-hybrid system in exploration of the yeast protein interactome2002
- Author(s)
  Ito, T., Ota, K., Kubota, H., Yamaguchi, Y., Chiba, T., Sakuraba, K., Yoshida, M.
- Journal Title
  
  Mol.Cell.Proteomics 1
  
  Pages: 561-566
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] Budding yeast GCN1 binds the GI domain to activate the eIF2α kinase GCN22001
- Author(s)
  Kubota, H., Ota, K., Sakaki, Y., Ito, T.
- Journal Title
  
  J.Biol.Chem. 276
  
  Pages: 17591-17596
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] Budding yeast GCN1 binds the GI domain to activate the eIF2α kinase GCN22001
- Author(s)
  Kubota, H., Ota, K., Sakaki, Y., Ito, T.
- Journal Title
  
  J. Biol. Chem. 276
  
  Pages: 17591-17596
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] Novel modular domain PB1 recognizes PC motif to mediate functional protein-protein interactions2001
- Author(s)
  Ito, T., Matsui, Y., Ago, T., Ota, K., Sumimoto, H.
- Journal Title
  
  EMBO J. 20
  
  Pages: 3938-3946
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] GI domain-mediated association of the eukaryotic initiation factor 2α kinase GCN2 with its activator GCN1 is required for general amino acid control in budding yeast2000
- Author(s)
  Kubota, H., Sakaki, Y., Ito, T.
- Journal Title
  
  J. Biol. Chem. 275
  
  Pages: 20243-20246
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Journal Article] GI domain-mediated association of the eukaryotic initiation factor 2a kinase GCN2 with its activator GCN1 is required for general amino acid control in budding yeast2000
- Author(s)
  Kubota, H., Sakaki, Y., Ito, T.
- Journal Title
  
  J.Biol.Chem. 275
  
  Pages: 20243-20246
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15014213
[Presentation] Ubp6によるRpn1のユビキチン化状態の制御2012
- Author(s)
  太田一寿
- Organizer
  第３５回　日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡　福岡市
- Data Source
  KAKENHI-PROJECT-23510233
[Presentation] F-box protein機能の統一的理解を目指して2011
- Author(s)
  太田一寿
- Organizer
  日本分子生物学会第３４回年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23510233
[Presentation] RSP5機能のユビキチン化による制御機構2010
- Author(s)
  太田一寿、紀藤圭治、伊藤隆司
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21710200
[Presentation] ミトコンドリア外膜蛋白質MDM34のユビキチン化機構2009
- Author(s)
  太田一寿・岡田悟・伊藤隆司
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21710200
[Presentation] USP型脱ユビキチン化酵素の網羅的基質探索2009
- Author(s)
  廣田剛志・太田一寿・紀藤圭治・伊藤隆司
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21710200

1. ITO Takashi (90201326)

# of Collaborated Projects: 10 results

# of Collaborated Products: 16 results
2. 萩原百合子 (70322732)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. SUMMOTO Hidekl (30179303)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. KITO Keiji (40345632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAMADA Yoichi (30377402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Ota Kazuhisa 太田 一寿

OTA Kazuhisa 太田 一寿

Research Projects

Research Products

Co-Researchers

Transomic analysis of adaptation induced by a synthetic gene circuit

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of 5-hydroxymethylcytosine: genome-wide mapping and screening for binding proteins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Systematic identification and classification of polyubiquitinated proteins with specific chain linkage patterns.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A systematic search for potential substrates of deubiquitinase with quantitative proteomicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ポリユビキチン化蛋白質の定量的プロファイリングの試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ポリユビキチン化基質蛋白質の網羅的同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

SYSTEMATIC COLLECTION OF BASIS INFORMATION FOR PROTEIN INTERACTION PREDICTION

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒトゲノム情報に基づく系統的メチル化解析によるがん関連インプリント遺伝子の検索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A NOVEL MECHANISM FOR TRANSLATION CONTROL REGULATION OF GCN PATHWAY BY TOR AND GI DOMAIN PROTEINS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

構造生物学研究へのゲノムリソース活用促進技術の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ゲノム的アプローチによるがん関連遺伝子としてのインプリント遺伝子の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

蛋白質間相互作用ドメインへのゲノム的アプローチ

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

蛋白質―蛋白質相互作用情報の系統的解析

Principal Investigator

Project Period (FY)

Ota Kazuhisa 太田一寿

OTA Kazuhisa 太田一寿