Yamauchi Yasuhiro 山内康宏

… Alternative Names

YAMAUCHI Yasuhiro 山内康宏

山内康宏ヤマウチヤスヒロ

Less

Researcher Number	00323585
Affiliation (Current)	2025: 東京外国語大学, 保健管理センター , 教授
Affiliation (based on the past Project Information) *help	2022: 東京外国語大学, 保健管理センター, 教授 2019 – 2021: 東京外国語大学, 保健管理センター, 准教授 2015 – 2018: 東京大学, 医学部附属病院, 講師 2011 – 2014: 東京大学, 保健・健康推進本部, 助教 2012: 東京大学, 学内共同利用施設等, 助教 2009: The University of Tokyo, 医学部附属病院, 助教 2007 – 2008: The University of Tokyo, 医学部・附属病院, 助教
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related Except Principal Investigator Respiratory organ internal medicine
Keywords	Principal Investigator 気道炎症 / E-cadherin / 線維化 / Vimentin / 肺線維症 / 気腫 / フロント阻害剤 / フロント / マクロファージ / 難治性重症呼吸器疾患 … More / COPD / 炎症性サイトカイン / ZC3H12A / 慢性閉塞性肺疾患 / 免疫調整因子 / 細胞内シグナリング経路 / ZC3H12A/MCPIP / 気道上皮細胞 / 慢性気道炎症性疾患 / EMT / LIGHT/ TNFSF14 / LIGHT/TNFSF14 / 上皮間葉転換 / vimentin / 肺線維芽細胞 / BMP-7 / リモデリング / 肺胞上皮細胞 / 線維芽細胞 / Bone Morphogenic protein / E-cadhrein / 間葉-上皮細胞転換 … More Except Principal Investigator EGFR / ブレオマイシン / マウス / EGFRファミリー / プロテオグリカン / 肺線維症 Less

Development of new treatment strategy for intractable severe respiratory disease focusing on the macrophage-FROUNTPrincipal Investigator
- Principal Investigator
  
  Yamauchi Yasuhiro
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tokyo University of Foreign Studies
  The University of Tokyo
Evaluation of functions of ZC3H12A/MCPIP in airway inflammationPrincipal Investigator
- Principal Investigator
  
  YAMAUCHI YASUHIRO
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Mechanism of epithelial mesenchymal transition induced by LIGHT/TNFSF14Principal Investigator
- Principal Investigator
  
  YAMAUCHI Yasuhiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
The role of proteoglycans in the modulation of EGFR family and it's ligand in lung fibrosis
- Principal Investigator
  
  JO Taisuke
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
肺線維芽細胞の間葉-上皮細胞転換の役割とその機序の解明Principal Investigator
- Principal Investigator
  
  山内康宏
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo

All 2016 2015 2014 2013 2012 2010 2009 2008 2007 Other

All Journal Article Presentation Book

[Book] 喘息診療こんな時どうするQ&A2008
- Author(s)
  福沢始編山内康宏
- Total Pages
  20
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19659210
[Journal Article] Effect of outpatient therapy with inhaled corticosteroids on decreasing in-hospital mortality from pneumonia in patients with COPD.2016
- Author(s)
  Yamauchi Y, Yasunaga H, Hasegawa W, Sakamoto Y, Takeshima H, Jo T, Matsui H, Fushimi K, Nagase T
- Journal Title
  
  Int J Chron Obstruct Pulmon Dis
  
  Volume: 11 Pages: 1403-1411
- DOI
  10.2147/copd.s107985
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-15K09211
[Journal Article] Mortality associated with bone fractures in COPD patients2016
- Author(s)
  Yamauchi Y, Yasunaga H, Sakamoto Y, Hasegawa W, Takeshima H, Urushiyama H, Jo T, Matsui H, Fushimi K, Nagase T.
- Journal Title
  
  Int J Chron Obstruct Pulmon Dis
  
  Volume: 11 Pages: 2335-2340
- DOI
  10.2147/copd.s112142
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-15K09211
[Journal Article] Comparison of clinical characteristics and outcomes between aspiration pneumonia and community-acquired pneumonia in patients with chronic obstructive pulmonary disease.2015
- Author(s)
  Yamauchi Y, Yasunaga H, Matsui H, et al.
- Journal Title
  
  BMC Pulm Med
  
  Volume: 15 Issue: 1 Pages: 69-69
- DOI
  10.1186/s12890-015-0064-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09211, KAKENHI-PROJECT-23249045
[Journal Article] Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells.2015
- Author(s)
  MatsuzakiH, Mikami Y, Yamauchi Y ,et al.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 10 Pages: 10-10
- DOI
  10.1371/journal.pone.0141746
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09211, KAKENHI-PROJECT-23249045
[Journal Article] Comparison of in-hospital mortality in patients with COPD, asthma and asthma-COPD overlap exacerbations.2015
- Author(s)
  Yamauchi Y, Yasunaga H, Matsui H, et al.
- Journal Title
  
  Respirology
  
  Volume: 20 Issue: 6 Pages: 940-946
- DOI
  10.1111/resp.12556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09211, KAKENHI-PROJECT-23249045
[Journal Article] Lymphotoxin β receptor signaling induces IL-8 production in human bronchial epithelial cells.2014
- Author(s)
  Mikami Y, Matsuzaki H, Horie M, Noguchi S, Jo T, Narumoto O, Kohyama T, Takizawa H, Nagase T, Yamauchi Y.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 12 Pages: 1-21
- DOI
  10.1371/journal.pone.0114791
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22240066, KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-24591125
[Journal Article] Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor2014
- Author(s)
  Horie M, Saito A, Yamauchi Y, Mikami Y, Sakamoto M, Jo T, Takizawa H, Nagase T, Kohyama T
- Journal Title
  
  Experimental Lung Research
  
  Volume: 未確定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591139
[Journal Article] Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor.2014
- Author(s)
  5.Horie M, Saito A, Yamauchi Y, Mikami Y, Sakamoto M, Jo T, Nakajima J, Takizawa H, Nagase T, Kohyama T.
- Journal Title
  
  Exp Lung Res.
  
  Volume: 40 Issue: 5 Pages: 222-36
- DOI
  10.3109/01902148.2014.900155
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-23591139, KAKENHI-PROJECT-23790899, KAKENHI-PROJECT-24591154, KAKENHI-PROJECT-26461185
[Journal Article] Tumor necrosis factor superfamily member LIGHT induces epithelial-mesenchymal transition in A549 human alveolar epithelial cells.2012
- Author(s)
  Mikami Y
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 428 Issue: 4 Pages: 451-7
- DOI
  10.1016/j.bbrc.2012.10.097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-23591139, KAKENHI-PROJECT-24591125
[Journal Article] Tumor necrosis factor- alpha enhances both epithelial-mesenchymal transition and cell contraction induced in A549 human alveolar epithelial cells by transforming growth factor-betal2010
- Author(s)
  Yamauchi Y, Kohyama T, et al
- Journal Title
  
  Exp Lung Res. 36
  
  Pages: 12-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659210
[Journal Article] Histamine stimulates human lung fibroblast migration2010
- Author(s)
  Kohyama T, Yamauchi Y, et al
- Journal Title
  
  Mol Cell Biochem. 337
  
  Pages: 77-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659210
[Journal Article] Procaterol inhibits lung fibroblast migration2009
- Author(s)
  Kohyama T, Yamauchi Y, et al
- Journal Title
  
  Inflammation 32
  
  Pages: 387-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659210
[Journal Article] 気道構成細胞と喘息2007
- Author(s)
  山内康宏
- Journal Title
  
  喘息 20
  
  Pages: 4-9
- Data Source
  KAKENHI-PROJECT-19659210
[Presentation] Interleukin-17A Enhances Interferon- Gamma-Induced CXCL10/IP-10 Production In BEAS-2B Human Bronchial Epithelial Cells2013
- Author(s)
  Yasuhiro Yamauchi, Taisuke Jo, Masafumi Horie, Yu Mikami, Satoshi Noguchi, Osamu Narumoto, Kazutaka Takami, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  Pennsylvania Convention Center
- Data Source
  KAKENHI-PROJECT-23591139
[Presentation] Interleukin-17A Enhances Interferon-Gamma-Induced CXCL10/IP-10 Production In BEAS-2B Human Bronchial Epithelial Cells.2013
- Author(s)
  Yasuhiro Yamauchi, Taisuke Jo, Masafumi Horie, Yu Mikami, Satoshi Noguchi, Osamu Narumoto, Kazutaka Takami, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase,
- Organizer
  American Thoracic Society　International Conference 2013
- Place of Presentation
  Pennsylvania convention center (アメリカ、フィラデルフィア）
- Data Source
  KAKENHI-PROJECT-23591139
[Presentation] Tumor Necrosis Factor Super Family Member LIGHT Induces CXCL8 Production In BEAS-2B Human Bronchial Epithelial Cells Via Erk1/2 Pathway.2013
- Author(s)
  Yu Mikami, Yasuhiro Yamauchi, Masafumi Horie, Satoshi Noguchi, Osamu Narumoto, Taisuke Jo, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase
- Organizer
  American Thoracic Society　International Conference 2013
- Place of Presentation
  Pennsylvania convention center (アメリカ、フィラデルフィア）
- Data Source
  KAKENHI-PROJECT-23591139
[Presentation] Tumor Necrosis Factor Super Family Member LIGHT Induces CXCL8 Production In BEAS-2B Human Bronchial Epithelial Cells Via Erk1/2 Pathway2013
- Author(s)
  Y Mikami, Y Yamauchi, M Horie, S Noguchi, O Narumoto, T Jo, T Kohyama, H Takizawa, T Nagase
- Organizer
  American Thoracic Society International Conference 2013
- Place of Presentation
  Penｎsylvania convention center (アメリカ・フィラデルフィア)
- Data Source
  KAKENHI-PROJECT-24591125
[Presentation] Tumor Necrosis Factor Super Family Member LIGHT Induces CXCL8 Production In BEAS-2B Human Bronchial Epithelial Cells Via Erk1/2 Pathway2013
- Author(s)
  Yu Mikami, Yasuhiro Yamauchi, Masafumi Horie, Satoshi Noguchi, Osamu Narumoto, Taisuke Jo, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  Pennsylvania Convention Center
- Data Source
  KAKENHI-PROJECT-23591139
[Presentation] Cellular and morecular mechanisms of epithelial mesenchymal transition in airway epithelial cells under airway inflammation2013
- Author(s)
  Y Yamauchi
- Organizer
  Asian Pacific Society of Respirology International Conference 2013
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Invited
- Data Source
  KAKENHI-PROJECT-24591125
[Presentation] Tumor Necrosis Factor Superfamily Member LIGHT (TNFSF14) Induces Epithelial-Mesenchymal Transition In A549 Human Airway Epithelial Cells2012
- Author(s)
  Y Mikami, Y Yamauchi, T Kohyama, M Horie, A Saito, T Jo, H Takizawa, T Nagase
- Organizer
  American Thoracic Society International conferrence 2012
- Place of Presentation
  The Moscone Center （アメリカ・サンフランシスコ）
- Data Source
  KAKENHI-PROJECT-24591125
[Presentation] Chemokine profiles of A549 human alveolar epithelial cells that underwent epithelial-mesenchymal transition by TGF-b and/or TNF-a2012
- Author(s)
  Y Yamauchi, M Horie, A Saito, T Jo, Y Mikami, H Takizawa, T Nagase, T Kohyama
- Organizer
  European Respiratory Society Annual congress 2012
- Place of Presentation
  Reed Messe Wien （オーストリア・ウィーン）
- Data Source
  KAKENHI-PROJECT-24591125
[Presentation] The comparison of functions between senescent and young fibroblasts2009
- Author(s)
  Yamauchi Y, Kohyama T, et al
- Organizer
  American thoracic society International conference
- Place of Presentation
  San Diego USA
- Year and Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-19659210
[Presentation] Epithelial mesenchymal taransition modulates the cell proliferation of lung epithelial cells2009
- Author(s)
  Yamauchi Y, Kohyama T, et al
- Organizer
  American thoracic society International conference
- Place of Presentation
  San Diego USA
- Year and Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-19659210
[Presentation] Clinical feature of elderly patients with lung cancer2008
- Author(s)
  山内康宏
- Organizer
  European Respiratory Society
- Place of Presentation
  Berlin, Germany
- Year and Date
  2008-10-06
- Data Source
  KAKENHI-PROJECT-19659210
[Presentation] 肺胞上皮細胞でのTGF-b1誘導による上皮間葉転換へのIFN-g,IL-4,TNF-aのサイトカインの効果2008
- Author(s)
  山内康宏
- Organizer
  日本呼吸器学会総会
- Place of Presentation
  東京、日本
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-19659210
[Presentation] The Effect of Bone Morphogenic Protein-7 on Mesenchymal Epit helial Transition from alveolar epithelial cells2008
- Author(s)
  山内康宏
- Organizer
  American Thoracic Society
- Place of Presentation
  Toronto, Canada
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-19659210
[Presentation] Epithelial mesenchymal transition in airway epithelial cells
- Author(s)
  Y Yamauchi
- Organizer
  Asian Pacific Society of Respirology International Conference 2014
- Place of Presentation
  Bali （インドネシア・バリ）
- Year and Date
  2014-11-13 – 2014-11-16
- Invited
- Data Source
  KAKENHI-PROJECT-24591125

1. JO Taisuke (30376470)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
2. KOHYAMA Tadashi (00302703)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. SAITO Akira (90591412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. NAGASE Takaide (40208004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. 漆山博和 (20725303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 相馬邦彦 (20806583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 寺島裕也 (90538729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yamauchi Yasuhiro 山内 康宏

YAMAUCHI Yasuhiro 山内 康宏

山内 康宏 ヤマウチ ヤスヒロ

Research Projects

Research Products

Co-Researchers

Development of new treatment strategy for intractable severe respiratory disease focusing on the macrophage-FROUNTPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of functions of ZC3H12A/MCPIP in airway inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of epithelial mesenchymal transition induced by LIGHT/TNFSF14Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of proteoglycans in the modulation of EGFR family and it's ligand in lung fibrosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肺線維芽細胞の間葉-上皮細胞転換の役割とその機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 喘息診療 こんな時どうするQ&A2008

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Effect of outpatient therapy with inhaled corticosteroids on decreasing in-hospital mortality from pneumonia in patients with COPD.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mortality associated with bone fractures in COPD patients2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of clinical characteristics and outcomes between aspiration pneumonia and community-acquired pneumonia in patients with chronic obstructive pulmonary disease.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of in-hospital mortality in patients with COPD, asthma and asthma-COPD overlap exacerbations.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lymphotoxin β receptor signaling induces IL-8 production in human bronchial epithelial cells.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor2014

Author(s)

Journal Title

Data Source

[Journal Article] Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor.2014

Author(s)

Journal Title

DOI

Data Source

Yamauchi Yasuhiro 山内康宏

YAMAUCHI Yasuhiro 山内康宏

山内康宏ヤマウチヤスヒロ

[Book] 喘息診療こんな時どうするQ&A2008