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Yamauchi Yasuhiro  山内 康宏

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YAMAUCHI Yasuhiro  山内 康宏

山内 康宏  ヤマウチ ヤスヒロ

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Researcher Number 00323585
Affiliation (Current) 2025: 東京外国語大学, 保健管理センター , 教授
Affiliation (based on the past Project Information) *help 2022: 東京外国語大学, 保健管理センター, 教授
2019 – 2021: 東京外国語大学, 保健管理センター, 准教授
2015 – 2018: 東京大学, 医学部附属病院, 講師
2011 – 2014: 東京大学, 保健・健康推進本部, 助教
2012: 東京大学, 学内共同利用施設等, 助教
2009: The University of Tokyo, 医学部附属病院, 助教
2007 – 2008: The University of Tokyo, 医学部・附属病院, 助教
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related
Except Principal Investigator
Respiratory organ internal medicine
Keywords
Principal Investigator
気道炎症 / E-cadherin / 線維化 / Vimentin / 肺線維症 / 気腫 / フロント阻害剤 / フロント / マクロファージ / 難治性重症呼吸器疾患 … More / COPD / 炎症性サイトカイン / ZC3H12A / 慢性閉塞性肺疾患 / 免疫調整因子 / 細胞内シグナリング経路 / ZC3H12A/MCPIP / 気道上皮細胞 / 慢性気道炎症性疾患 / EMT / LIGHT/ TNFSF14 / LIGHT/TNFSF14 / 上皮間葉転換 / vimentin / 肺線維芽細胞 / BMP-7 / リモデリング / 肺胞上皮細胞 / 線維芽細胞 / Bone Morphogenic protein / E-cadhrein / 間葉-上皮細胞転換 … More
Except Principal Investigator
EGFR / ブレオマイシン / マウス / EGFRファミリー / プロテオグリカン / 肺線維症 Less
  • Research Projects

    (5 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (7 People)
  •  Development of new treatment strategy for intractable severe respiratory disease focusing on the macrophage-FROUNTPrincipal Investigator

    • Principal Investigator
      Yamauchi Yasuhiro
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Tokyo University of Foreign Studies
      The University of Tokyo
  •  Evaluation of functions of ZC3H12A/MCPIP in airway inflammationPrincipal Investigator

    • Principal Investigator
      YAMAUCHI YASUHIRO
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      The University of Tokyo
  •  Mechanism of epithelial mesenchymal transition induced by LIGHT/TNFSF14Principal Investigator

    • Principal Investigator
      YAMAUCHI Yasuhiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      The University of Tokyo
  •  The role of proteoglycans in the modulation of EGFR family and it's ligand in lung fibrosis

    • Principal Investigator
      JO Taisuke
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      The University of Tokyo
  •  肺線維芽細胞の間葉-上皮細胞転換の役割とその機序の解明Principal Investigator

    • Principal Investigator
      山内 康宏
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      The University of Tokyo

All 2016 2015 2014 2013 2012 2010 2009 2008 2007 Other

All Journal Article Presentation Book

  • [Book] 喘息診療 こんな時どうするQ&A2008

    • Author(s)
      福沢始編 山内康宏
    • Total Pages
      20
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-19659210
  • [Journal Article] Effect of outpatient therapy with inhaled corticosteroids on decreasing in-hospital mortality from pneumonia in patients with COPD.2016

    • Author(s)
      Yamauchi Y, Yasunaga H, Hasegawa W, Sakamoto Y, Takeshima H, Jo T, Matsui H, Fushimi K, Nagase T
    • Journal Title

      Int J Chron Obstruct Pulmon Dis

      Volume: 11 Pages: 1403-1411

    • DOI

      10.2147/copd.s107985

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-15K09211
  • [Journal Article] Mortality associated with bone fractures in COPD patients2016

    • Author(s)
      Yamauchi Y, Yasunaga H, Sakamoto Y, Hasegawa W, Takeshima H, Urushiyama H, Jo T, Matsui H, Fushimi K, Nagase T.
    • Journal Title

      Int J Chron Obstruct Pulmon Dis

      Volume: 11 Pages: 2335-2340

    • DOI

      10.2147/copd.s112142

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02653, KAKENHI-PROJECT-15K09211
  • [Journal Article] Comparison of clinical characteristics and outcomes between aspiration pneumonia and community-acquired pneumonia in patients with chronic obstructive pulmonary disease.2015

    • Author(s)
      Yamauchi Y, Yasunaga H, Matsui H, et al.
    • Journal Title

      BMC Pulm Med

      Volume: 15 Issue: 1 Pages: 69-69

    • DOI

      10.1186/s12890-015-0064-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09211, KAKENHI-PROJECT-23249045
  • [Journal Article] Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells.2015

    • Author(s)
      MatsuzakiH, Mikami Y, Yamauchi Y ,et al.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 10 Pages: 10-10

    • DOI

      10.1371/journal.pone.0141746

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09211, KAKENHI-PROJECT-23249045
  • [Journal Article] Comparison of in-hospital mortality in patients with COPD, asthma and asthma-COPD overlap exacerbations.2015

    • Author(s)
      Yamauchi Y, Yasunaga H, Matsui H, et al.
    • Journal Title

      Respirology

      Volume: 20 Issue: 6 Pages: 940-946

    • DOI

      10.1111/resp.12556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09211, KAKENHI-PROJECT-23249045
  • [Journal Article] Lymphotoxin β receptor signaling induces IL-8 production in human bronchial epithelial cells.2014

    • Author(s)
      Mikami Y, Matsuzaki H, Horie M, Noguchi S, Jo T, Narumoto O, Kohyama T, Takizawa H, Nagase T, Yamauchi Y.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 12 Pages: 1-21

    • DOI

      10.1371/journal.pone.0114791

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22240066, KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-24591125
  • [Journal Article] Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor2014

    • Author(s)
      Horie M, Saito A, Yamauchi Y, Mikami Y, Sakamoto M, Jo T, Takizawa H, Nagase T, Kohyama T
    • Journal Title

      Experimental Lung Research

      Volume: 未確定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591139
  • [Journal Article] Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor.2014

    • Author(s)
      5.Horie M, Saito A, Yamauchi Y, Mikami Y, Sakamoto M, Jo T, Nakajima J, Takizawa H, Nagase T, Kohyama T.
    • Journal Title

      Exp Lung Res.

      Volume: 40 Issue: 5 Pages: 222-36

    • DOI

      10.3109/01902148.2014.900155

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-23591139, KAKENHI-PROJECT-23790899, KAKENHI-PROJECT-24591154, KAKENHI-PROJECT-26461185
  • [Journal Article] Tumor necrosis factor superfamily member LIGHT induces epithelial-mesenchymal transition in A549 human alveolar epithelial cells.2012

    • Author(s)
      Mikami Y
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 428 Issue: 4 Pages: 451-7

    • DOI

      10.1016/j.bbrc.2012.10.097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-23591139, KAKENHI-PROJECT-24591125
  • [Journal Article] Tumor necrosis factor- alpha enhances both epithelial-mesenchymal transition and cell contraction induced in A549 human alveolar epithelial cells by transforming growth factor-betal2010

    • Author(s)
      Yamauchi Y, Kohyama T, et al
    • Journal Title

      Exp Lung Res. 36

      Pages: 12-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659210
  • [Journal Article] Histamine stimulates human lung fibroblast migration2010

    • Author(s)
      Kohyama T, Yamauchi Y, et al
    • Journal Title

      Mol Cell Biochem. 337

      Pages: 77-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659210
  • [Journal Article] Procaterol inhibits lung fibroblast migration2009

    • Author(s)
      Kohyama T, Yamauchi Y, et al
    • Journal Title

      Inflammation 32

      Pages: 387-392

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659210
  • [Journal Article] 気道構成細胞と喘息2007

    • Author(s)
      山内 康宏
    • Journal Title

      喘息 20

      Pages: 4-9

    • Data Source
      KAKENHI-PROJECT-19659210
  • [Presentation] Interleukin-17A Enhances Interferon- Gamma-Induced CXCL10/IP-10 Production In BEAS-2B Human Bronchial Epithelial Cells2013

    • Author(s)
      Yasuhiro Yamauchi, Taisuke Jo, Masafumi Horie, Yu Mikami, Satoshi Noguchi, Osamu Narumoto, Kazutaka Takami, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase
    • Organizer
      American Thoracic Society International Conference
    • Place of Presentation
      Pennsylvania Convention Center
    • Data Source
      KAKENHI-PROJECT-23591139
  • [Presentation] Interleukin-17A Enhances Interferon-Gamma-Induced CXCL10/IP-10 Production In BEAS-2B Human Bronchial Epithelial Cells.2013

    • Author(s)
      Yasuhiro Yamauchi, Taisuke Jo, Masafumi Horie, Yu Mikami, Satoshi Noguchi, Osamu Narumoto, Kazutaka Takami, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase,
    • Organizer
      American Thoracic Society International Conference 2013
    • Place of Presentation
      Pennsylvania convention center (アメリカ、フィラデルフィア)
    • Data Source
      KAKENHI-PROJECT-23591139
  • [Presentation] Tumor Necrosis Factor Super Family Member LIGHT Induces CXCL8 Production In BEAS-2B Human Bronchial Epithelial Cells Via Erk1/2 Pathway.2013

    • Author(s)
      Yu Mikami, Yasuhiro Yamauchi, Masafumi Horie, Satoshi Noguchi, Osamu Narumoto, Taisuke Jo, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase
    • Organizer
      American Thoracic Society International Conference 2013
    • Place of Presentation
      Pennsylvania convention center (アメリカ、フィラデルフィア)
    • Data Source
      KAKENHI-PROJECT-23591139
  • [Presentation] Tumor Necrosis Factor Super Family Member LIGHT Induces CXCL8 Production In BEAS-2B Human Bronchial Epithelial Cells Via Erk1/2 Pathway2013

    • Author(s)
      Y Mikami, Y Yamauchi, M Horie, S Noguchi, O Narumoto, T Jo, T Kohyama, H Takizawa, T Nagase
    • Organizer
      American Thoracic Society International Conference 2013
    • Place of Presentation
      Pennsylvania convention center (アメリカ・フィラデルフィア)
    • Data Source
      KAKENHI-PROJECT-24591125
  • [Presentation] Tumor Necrosis Factor Super Family Member LIGHT Induces CXCL8 Production In BEAS-2B Human Bronchial Epithelial Cells Via Erk1/2 Pathway2013

    • Author(s)
      Yu Mikami, Yasuhiro Yamauchi, Masafumi Horie, Satoshi Noguchi, Osamu Narumoto, Taisuke Jo, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase
    • Organizer
      American Thoracic Society International Conference
    • Place of Presentation
      Pennsylvania Convention Center
    • Data Source
      KAKENHI-PROJECT-23591139
  • [Presentation] Cellular and morecular mechanisms of epithelial mesenchymal transition in airway epithelial cells under airway inflammation2013

    • Author(s)
      Y Yamauchi
    • Organizer
      Asian Pacific Society of Respirology International Conference 2013
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591125
  • [Presentation] Tumor Necrosis Factor Superfamily Member LIGHT (TNFSF14) Induces Epithelial-Mesenchymal Transition In A549 Human Airway Epithelial Cells2012

    • Author(s)
      Y Mikami, Y Yamauchi, T Kohyama, M Horie, A Saito, T Jo, H Takizawa, T Nagase
    • Organizer
      American Thoracic Society International conferrence 2012
    • Place of Presentation
      The Moscone Center (アメリカ・サンフランシスコ)
    • Data Source
      KAKENHI-PROJECT-24591125
  • [Presentation] Chemokine profiles of A549 human alveolar epithelial cells that underwent epithelial-mesenchymal transition by TGF-b and/or TNF-a2012

    • Author(s)
      Y Yamauchi, M Horie, A Saito, T Jo, Y Mikami, H Takizawa, T Nagase, T Kohyama
    • Organizer
      European Respiratory Society Annual congress 2012
    • Place of Presentation
      Reed Messe Wien (オーストリア・ウィーン)
    • Data Source
      KAKENHI-PROJECT-24591125
  • [Presentation] The comparison of functions between senescent and young fibroblasts2009

    • Author(s)
      Yamauchi Y, Kohyama T, et al
    • Organizer
      American thoracic society International conference
    • Place of Presentation
      San Diego USA
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-19659210
  • [Presentation] Epithelial mesenchymal taransition modulates the cell proliferation of lung epithelial cells2009

    • Author(s)
      Yamauchi Y, Kohyama T, et al
    • Organizer
      American thoracic society International conference
    • Place of Presentation
      San Diego USA
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-19659210
  • [Presentation] Clinical feature of elderly patients with lung cancer2008

    • Author(s)
      山内 康宏
    • Organizer
      European Respiratory Society
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2008-10-06
    • Data Source
      KAKENHI-PROJECT-19659210
  • [Presentation] 肺胞上皮細胞でのTGF-b1誘導による上皮間葉転換へのIFN-g,IL-4,TNF-aのサイトカインの効果2008

    • Author(s)
      山内 康宏
    • Organizer
      日本呼吸器学会総会
    • Place of Presentation
      東京、日本
    • Year and Date
      2008-06-16
    • Data Source
      KAKENHI-PROJECT-19659210
  • [Presentation] The Effect of Bone Morphogenic Protein-7 on Mesenchymal Epit helial Transition from alveolar epithelial cells2008

    • Author(s)
      山内 康宏
    • Organizer
      American Thoracic Society
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2008-05-18
    • Data Source
      KAKENHI-PROJECT-19659210
  • [Presentation] Epithelial mesenchymal transition in airway epithelial cells

    • Author(s)
      Y Yamauchi
    • Organizer
      Asian Pacific Society of Respirology International Conference 2014
    • Place of Presentation
      Bali (インドネシア・バリ)
    • Year and Date
      2014-11-13 – 2014-11-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591125
  • 1.  JO Taisuke (30376470)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 8 results
  • 2.  KOHYAMA Tadashi (00302703)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 3.  SAITO Akira (90591412)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  NAGASE Takaide (40208004)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 5.  漆山 博和 (20725303)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  相馬 邦彦 (20806583)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  寺島 裕也 (90538729)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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