NOMURA Akihiko 野村明彦

Researcher Number	00325531
Other IDs
Affiliation (based on the past Project Information) *help	2005: 九州大学, 病院・助手 2004 – 2005: 九州大学, 大学病院, 助手 2002 – 2004: Kyushu University, Graduate School of Medical Sciences, Teaching staff, 大学院・医学研究院, 助手 2001 – 2002: 九州大学, 医学部附属病院, 助手 2000 – 2001: Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Assistant Professor, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Embryonic/Neonatal medicine / Embryonic/Neonatal medicine Except Principal Investigator Pediatrics / Pediatrics
Keywords	Principal Investigator NK細胞 / 臍帯血 / Foxp3 / ナイーブT細胞 / CD25陽性CD4陽性T細胞 / 制御性T細胞 / Insulin-like growth factor II / 有核赤血球 / Toll-like recetor / DNAマイクロアレイ … More / IL-18 / IL-10 / CD34細胞 / CD25 / 抑制性T細胞 / CD45分子 / CD34陽性細胞 / 血管内皮細胞 / GITR / TREC / CD25分子 / 抑制性CD4T細胞 … More Except Principal Investigator T-bet / Th2 / Th1 / CXCL7 / IRF-1 / IL-4 / 結核 / EBV-DNA / Quantitative PCR / Rapid diagnosis / Microarray / Hyper-IgE syndrome / 定量的PCR法 / 迅速診断 / マイクロアレイ / 高IgE症候群 / dendritic cell / Sendai virus vector / osteopontin / Mycobacterium / macrophage / intracellular bacteria / 結核感染マウスモデル / 細胞遺伝子療法 / IFN-γ / 細胞免疫療法 / 樹状細胞 / センダイウイルスベクター / Osteopontin / 結核菌 / マクロファージ / 細胞内寄生性細菌 / cord blood / vector / Sendai virus / gene transfer / hematopoietic stem cells / gene therapy / 臍帯血 / ベクター / センダイウイルス / 遺伝子導入 / 造血幹細胞 / 遺伝子治療 / interferon γ / allergy / Tuberculosis / IRF-I / アドレナリン受容体 / レセプター / インターフェロンγ / アレルギー / T helper (Th) 1 / cytokine / lymphoproliferative diseases (disorders) / chronic active Epstein-Barr virus infection / 細胞内サイトカイン / EBVウイルス量 / 慢性活動性EBV感染症 / サイトカイン / リンパ増殖性疾患 / 慢性活動性EBウイルス感染症 Less

Pathogenesis of hyper-IgE syndrome and establishment of a method for rapid diagnosis
- Principal Investigator
  
  TAKADA Hidetoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  KYUSHU UNIVERSITY
臍帯血CD25陽性CD4陽性T細胞およびNK細胞におけるDNAマイクロアレイ解析Principal Investigator
- Principal Investigator
  
  野村明彦
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kyushu University
Analysis of host responses to intracellular bacteria and development of cell-mediated gene therapy
- Principal Investigator
  
  HARA Toshiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  KYUSHU UNIVERSITY
Development of gene therapy using a novel domestic viral vector.
- Principal Investigator
  
  KUSUHARA Koichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyushu University
ヒト臍帯血リンパ球および血球・血管前駆細胞の機能解析Principal Investigator
- Principal Investigator
  
  野村明彦
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kyushu University
Delerminalion of polymorphisms associated with tuberculosis or asthma.
- Principal Investigator
  
  HARA Toshiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyushu University
T-cell analysis on chronic active Epstein-Barr virus (EBV) infection and EBV-associated lymphoproliferative diseases
- Principal Investigator
  
  OHGA Shouichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyushu University

All 2006 2005 2004 Other

All Journal Article

[Journal Article] Epstein-Barr virus associated bronchial leiomyoma in a boy with cellular immunodeficiency.2006
- Author(s)
  Hatano M, Takada H, Nomura A, Ohga S, Ohshima K, Saeki I, Tajiri T, Taguchi T, Suita S, Hara T
- Journal Title
  
  Pediatric Pulmonology 41・4
  
  Pages: 371-373
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Delayed separation of the umbilical cord in two siblings with IRAK4 deficiency : Rapid screening method by flow cytometer.2006
- Author(s)
  Takada H, Yoshikawa H, Imaizumi M, Kitamura T, Takeyama J, Kumaki S, Nomura A, Hara T
- Journal Title
  
  Journal of Pediatrics 148・4
  
  Pages: 546-548
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Novel Roles of Osteopontin and CXC Chemokine Ligand 7 in the Defense against Mycobacterial Infection.2006
- Author(s)
  Khajoee V, Saito M, Takada H, Nomura A, Kusuhara K, Yoshida SI, Yoshikai Y, Hara T
- Journal Title
  
  Clinical and Experimental Immunology 143・2
  
  Pages: 260-268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] T-cell-depleted CD34+ cell transplantation from an HLA-mismatched donor in a low-birthweight infant with X-linked severe combined immunodeficiency.2005
- Author(s)
  Nomura A, Takada H, Ohga S, Ishii N, Inoue T, Hara T
- Journal Title
  
  Journal of Pediatric Hematology and Oncology 27・2
  
  Pages: 80-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Distinct gene expression patterns of peripheral blood cells in hyper-IgE syndrome.2005
- Author(s)
  Tanaka T, Takada H, Nomura A, 他2名, Hara T
- Journal Title
  
  Clin Exp Immunol. 140
  
  Pages: 524-531
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] T-cell-depleted CD34+ cell transplantation from an HLA-mismatched donor in a low birth weight infannt with X-linked severe combined immunodeficiency2005
- Author(s)
  Nomura A, Takada H et al.
- Journal Title
  
  Journal of Pediatric Hematology/Oncology 27・2
  
  Pages: 80-84
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Prolonged severe pancytopenia preceding the cutaneous lesions of juvenile xanthogranuloma.2005
- Author(s)
  Hara T, Ohga S, Hattori S, Hatano M, Kaku N, Nomura A, Takada H, Kokuba H, Ohshima K, Hara T
- Journal Title
  
  Pediatric Blood and Cancer 26・47
  
  Pages: 103-106
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Successful umbilical cord blood transplantation for severe chronic active Epstein-Barr virus infection after the double failure of hematopoietic stem cell transplantation.2005
- Author(s)
  Ishimura M, Ohga S, Nomura A, Toubo T, Morihana E, Saito Y, Nishio H, Ide M, Takada H, Hara T
- Journal Title
  
  American Journal of Hematology 80・3
  
  Pages: 207-212
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Bronchiolitis obliterans organizing pneumonia as an initial manifestation in systemic lupus erythematosus.2005
- Author(s)
  Takada H, Saito Y, Nomura A, Ohga S, Kuwano K, Nakashima N, Aishima S, Tsuru N, Hara T
- Journal Title
  
  Pediatric Pulmonology 40・3
  
  Pages: 257-270
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] T-cell-depleted CD34+ cell transplantation from an HLA-mismatched donor in a low-birthweight infant with X-linked severe combined immunodeficiency.2005
- Author(s)
  Nomura A, Takada Hら
- Journal Title
  
  Journal of Pediatric Hematology and Oncology 27・2
  
  Pages: 80-84
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Distinct gene expression patterns of peripheral blood cells in hyper-IgE syndrome.2005
- Author(s)
  Tanaka T, Takada H, Nomura A, 他2名 Hara T
- Journal Title
  
  Clin Exp Immunol. 140
  
  Pages: 524-531
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] A novel CIAS1 mutation in a Japanese patient with chronic infantile neurological cutaneous and articular syndrome.2005
- Author(s)
  Takada H, Kusuhara K, Nomura A, Ohga S, Hayashi M, Furue M, Hara T
- Journal Title
  
  European Journal of Pediatrics 164・12
  
  Pages: 785-786
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] T-Cell-Depleted CD34+ Cell Transplantation From an HLAMismatched Donor in a Low-Birthweight Infant With X-Linked Severe Combined Immunodeficiency.2005
- Author(s)
  Nomura A, Takada H, et al.
- Journal Title
  
  J Pediatr Hematol Oncol 27(2)
  
  Pages: 80-84
- Data Source
  KAKENHI-PROJECT-15790554
[Journal Article] Distinct gene expression patterns of peripheral blood cells in hyper-IgE syndrome.2005
- Author(s)
  Tanaka T, Takada H, Nomura A, Ohga S, Shibata R, Hara T
- Journal Title
  
  Clinical and Experimental Immunology 140・3
  
  Pages: 524-531
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Severe combined immunodeficiency caused by a splicing abnormality of the CD3delta gene.2005
- Author(s)
  Takada H, Nomura A, Roifman CM, Hara T
- Journal Title
  
  European Journal of Pediatrics 164・5
  
  Pages: 311-314
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] CD25+CD4+ T cells in human cord blood: an immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene.2004
- Author(s)
  Takahata Y, Nomura A, Takada H, Ohga S, Furuno K, Hikino S, Nakayama H, Sakaguchi S, Hara T
- Journal Title
  
  Experimental Hematology 32・7
  
  Pages: 622-629
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Female agammaglobulinemia due to the Bruton tyrosine kinase deficiencycaused by extremely skewed X-chromosome inactivation.2004
- Author(s)
  Takada H, Nomura A, 他6名, Hara T
- Journal Title
  
  Blood 103
  
  Pages: 185-187
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] Hyper-IgE syndrome2004
- Author(s)
  Takada H, Nomura A, Hara T.
- Journal Title
  
  Nihon Rinsho Meneki Gakkai Kaishi 27(6)
  
  Pages: 361-366
- NAID
  10014261479
- Data Source
  KAKENHI-PROJECT-15790554
[Journal Article] Increased IL-16 levels in hemophagocytic lymphohistiocytosis.2004
- Author(s)
  Takada H, Nomura A, 他2名, Hara T
- Journal Title
  
  J Pediatr Hematol Oncol 26
  
  Pages: 567-573
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] Dominant expression of interleukin-10 and transforming growth factor-beta genes in activated T-cells of chronic active Epstein-Barr virus infection.2004
- Author(s)
  Ohga S, Nomura A, Takada H, Tanaka T, Furuno K, Takahata Y, Kinukawa N, Fukushima N, Imai S, Hara T
- Journal Title
  
  Journal of Medical Virology 74・3
  
  Pages: 449-458
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Microarray analysis of human milk cells : persistent high expression of osteopontin during the lactation period2004
- Author(s)
  Nagatomo T, Takada H, Nomura A, 他4名, Hara T
- Journal Title
  
  Clin Exp Immunol 138
  
  Pages: 47-53
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] CD25+CD4+ T cells in human cord blood : an immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene2004
- Author(s)
  Takahata Y, Nomura A, Takada H et al.
- Journal Title
  
  Experimental Hematology 32・7
  
  Pages: 622-629
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Human cord blood CD25+CD4+ T cells : a novel immunoregulatory population with naive phenotype.2004
- Author(s)
  Takahata Y, Nomura A, Takada H, 他5名, Hara T
- Journal Title
  
  Exp Hematol 32
  
  Pages: 622-629
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] Increased IL-16 levels in hemophagocytic lymphohistiocytosis.2004
- Author(s)
  Takada H, Ohga S, Mizuno Y, Nomura A, Hara T
- Journal Title
  
  Journal of Pediatric Hematology and Oncology 26・9
  
  Pages: 567-573
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Th1 and Th2 cytokine production is suppressed at the level of transcriptional regulation in Kawasaki disease.2004
- Author(s)
  Kimura J, Takada H, Nomura A, Kusuhara K, 他3名, Hara T
- Journal Title
  
  Clin Exp Immunol 137
  
  Pages: 444-449
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] Microarray analysis of human milk cells : persistent high expression of osteopontin during the lactation period.2004
- Author(s)
  Nagatomo T, Ohga S, Takada H, Nomura A, Hikino S, Imura M, Ohshima K, Hara T
- Journal Title
  
  Clinical and Experimental Immunology 138・1
  
  Pages: 47-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Dominant expression of interleukin-10 and transforming growth factor-beta genes in activated T-cells of chronic active Epstein-Barr virus infection2004
- Author(s)
  Ohga S, Nomura A, Takada H, et al.
- Journal Title
  
  Journal of Medical Virology 74・3
  
  Pages: 449-458
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Tumour necrosis factor receptor-associated periodic syndrome with a novel mutations in the TNFRSF1A gene in a Japanese family.2004
- Author(s)
  Kusuhara K, Nomura A, Nakao F, Hara T
- Journal Title
  
  Eur J Pediatr 163
  
  Pages: 30-32
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] Th1 and Th2 cytokine production is suppressed at the level of transcriptional regulation in Kawasaki disease.2004
- Author(s)
  Kimura J, Takada H, Nomura A, Ohno T, Mizuno Y, Saito M, Kusuhara K, Hara T
- Journal Title
  
  Clinical and Experimental Immunology 137・2
  
  Pages: 444-449
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] IPEX症候群2004
- Author(s)
  高田英俊, 野村明彦, 原寿郎
- Journal Title
  
  小児内科 36・11
  
  Pages: 1817-1820
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Female agammaglobulinemia due to the Bruton tyrosine kinase deficiency caused by extremely skewed X-chromosome inactivation.2004
- Author(s)
  Takada H, Kanegane H, Nomura A, Yamamoto K, Ihara K, Takahashi Y, Tsukada S, Miyawaki T, Hara T
- Journal Title
  
  Blood 103・1
  
  Pages: 185-187
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Dominant expression of interleukin10 and transforming growth factor beta genes in activated T-cells of chronic active Epstein-Barr virus infection.2004
- Author(s)
  Ohga S, Nomura A, et al.
- Journal Title
  
  J Med Virol 74(3)
  
  Pages: 449-458
- Data Source
  KAKENHI-PROJECT-15790554
[Journal Article] Successful unrelated cord blood transplantation for Epstein-Barr virus-associated lymphoproliferative disease with hemophagocytic syndrome.2004
- Author(s)
  Toubo T, Suga N, Ohga S, Nomura A, Onoe Y, Takada H, Hara T
- Journal Title
  
  International Journal of Hematology 80・5
  
  Pages: 458-462
- NAID
  10014089379
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] IPEX (Immune dysregulation, Polyendocrinopathy, Enteropathy, X-linked)症候群2004
- Author(s)
  高田英俊, 野村明彦, 原寿郎
- Journal Title
  
  アレルギー・免疫 11・12
  
  Pages: 36-40
- Data Source
  KAKENHI-PROJECT-16591040
[Journal Article] Dominant expression of interleukin-10 and transforming growth factor-genes in activated T-cells of chronic active Epstein-Barr virus infection.2004
- Author(s)
  Ohga S, Nomura A, Takada H, 他5名, Hara T
- Journal Title
  
  J Med Virol 74
  
  Pages: 449-458
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] Rapid screening method for IRAK4 deficiency by flow cytometer.
- Author(s)
  Takada H, 他5名, Nomura A, Hara T
- Journal Title
  
  J Pediatr (in press)
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] Bronchiolitis obliterans organizing pneumonia as an initial manifestation in a girl with systemic lupus erythematosus.
- Author(s)
  Takada H, Nomura A, 他6名, Hara T
- Journal Title
  
  Pediatric Pulmonology (in press)
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] Successful unrelated cord blood transplantation for Epstein-Barr virus-associated lymphoproliferative disease with hemophagocytic syndrome.
- Author(s)
  Toubo T, Nomura A, Takada H, 他4名, Hara T
- Journal Title
  
  Int J Hematol (in press)
- NAID
  10014089379
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] T-cell-depleted Cd34+ cell transplantation from an HLA-mismatched donor in a low birth weight infant with X-linked severe combined immunodeficiency.
- Author(s)
  Nomura A, Takada H, 他3名, Hara T
- Journal Title
  
  J Pediatric Hematol Oncol (in press)
- Data Source
  KAKENHI-PROJECT-15390325
[Journal Article] Rapid screening method for IRAK4 deficiency by flow cytometer.
- Author(s)
  Takada H 他5名 Nomura A, Hara T
- Journal Title
  
  J pediatr (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390325

1. HARA Toshiro (40150445)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
2. KUSUHARA Koichi (20243941)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. TAKADA Hidetoshi (70294931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 36 results
4. OHGA Shouichi (60233053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KANEMITSU Satomi (50315066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IHARA Kenji (80294932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YONEMITSU Yoshikazu (40315065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SAKAI Yasunari (10380396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YOSHIKAI Yasunobu (90158402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NOMURA Akihiko 野村 明彦

Research Projects

Research Products

Co-Researchers

Pathogenesis of hyper-IgE syndrome and establishment of a method for rapid diagnosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

臍帯血CD25陽性CD4陽性T細胞およびNK細胞におけるDNAマイクロアレイ解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of host responses to intracellular bacteria and development of cell-mediated gene therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of gene therapy using a novel domestic viral vector.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト臍帯血リンパ球および血球・血管前駆細胞の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Delerminalion of polymorphisms associated with tuberculosis or asthma.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

T-cell analysis on chronic active Epstein-Barr virus (EBV) infection and EBV-associated lymphoproliferative diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Epstein-Barr virus associated bronchial leiomyoma in a boy with cellular immunodeficiency.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Delayed separation of the umbilical cord in two siblings with IRAK4 deficiency : Rapid screening method by flow cytometer.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Novel Roles of Osteopontin and CXC Chemokine Ligand 7 in the Defense against Mycobacterial Infection.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] T-cell-depleted CD34+ cell transplantation from an HLA-mismatched donor in a low-birthweight infant with X-linked severe combined immunodeficiency.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Distinct gene expression patterns of peripheral blood cells in hyper-IgE syndrome.2005

Author(s)

Journal Title

Data Source

[Journal Article] T-cell-depleted CD34+ cell transplantation from an HLA-mismatched donor in a low birth weight infannt with X-linked severe combined immunodeficiency2005

Author(s)

Journal Title

Data Source

[Journal Article] Prolonged severe pancytopenia preceding the cutaneous lesions of juvenile xanthogranuloma.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Successful umbilical cord blood transplantation for severe chronic active Epstein-Barr virus infection after the double failure of hematopoietic stem cell transplantation.2005

NOMURA Akihiko 野村明彦