KAWASHIMA Motoko 川島素子

… Alternative Names

川島素子カワシマモトコ

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Researcher Number	00327610
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2019: 慶應義塾大学, 医学部(信濃町), 特任講師 2017: 慶應義塾大学, 医学部, 特任講師 2016: 慶應義塾大学, 医学部(信濃町), 特任講師 2014 – 2015: 慶應義塾大学, 医学部, 講師 2013 – 2014: 慶應義塾大学, 医学部, 特任講師 … More 2012: 慶應義塾大学, 医学部, 講師 2011: 慶應義塾大学, 医学部, 講師(非常勤) 2008 – 2010: Keio University, 医学部, 助教 2004: 東京歯科大学, 市川総合病院・眼科, 助手 Less
Review Section/Research Field	Principal Investigator Ophthalmology Except Principal Investigator Ophthalmology / Biological Sciences
Keywords	Principal Investigator ドライアイ / 涙腺 / 涙液 / 眼科 / BDNF / 豊かな環境 / うつ / ストレス / 環境因子 / 涙液分泌 … More / 糖尿病 / 細胞生物学 / 細胞組織 / 外科 / 再生医学 … More Except Principal Investigator ドライアイ / 眼 / NAD / 眼科学 / Fuchs角膜内皮変性症 / 緑内障 / NAD代謝 / 抗加齢医学 / NMN / NAD関連代謝 / ミトコンドリア / 酸化ストレス / CR / Sirtuin / マイボグラフィ / MGD / マイボーム腺 / 活性型ビタミンD3 / マイボーム腺機能不全 / ELISA / 涙液 / 唾液腺 / 細胞膜固定 / C末結合タンパク質 / 膜輸送機構 / major urinary protein-4 / prolactin-inducible protein / odorant-binding protein-Ia / C末端結合タンパク質 / 涙腺 / シェーグレン症候群 / アクアポリン5 Less

A novel prevention and treatment method of ocular aging by targeting sirtuins.
- Principal Investigator
  
  TSUBOTA Kazuo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Investigation of tear secretion mechanism focus on environmental factorPrincipal Investigator
- Principal Investigator
  
  KAWASHIMA Motoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Clinical safety and efficacy of vitamin D3 analog ointment for treatment of obstructive meibomian gland dysfunction
- Principal Investigator
  
  Arita Reiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
tear secretion and AMPKPrincipal Investigator
- Principal Investigator
  
  KAWASHIMA Motoko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Mechanism of decreased tear secretion in mice with metabolic syndromePrincipal Investigator
- Principal Investigator
  
  KAWASHIMA Motoko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
The role of limbal melanocytes in interaction between limbal stem cells and melanocytesPrincipal Investigator
- Principal Investigator
  
  KAWASHIMA Motoko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
涙液産生におけるアクアポリン5の生理的役割の解明
- Principal Investigator
  
  TSUBOTA Kazuo
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
  Tokyo Dental College

All 2020 2019 2015 2014 2011 Other

All Journal Article Presentation

[Journal Article] Advances in the Diagnosis and Treatment of Dry Eye2020
- Author(s)
  Kojima T, Dogru M, Kawashima M, Nakamura S, Tsubota K.
- Journal Title
  
  Prog Retin Eye Res.
  
  Volume: - Pages: 1-26
- DOI
  10.1016/j.preteyeres.2020.100842
- Open Access
- Data Source
  KAKENHI-PROJECT-17H04353
[Journal Article] Hydrogen-producing milk to prevent reduction in tear stability in persons using visual display terminals.2019
- Author(s)
  Kawashima M, Tsuno S, Matsumoto M, Tsubota K
- Journal Title
  
  Ocul Surf
  
  Volume: 17(4) Issue: 4 Pages: 714-721
- DOI
  10.1016/j.jtos.2019.07.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04353
[Journal Article] Enriched environment alleviates stress-induced dry-eye through the BDNF axis2019
- Author(s)
  Sano Kokoro、Kawashima Motoko、Imada Toshihiro、Suzuki Toru、Nakamura Shigeru、Mimura Masaru、Tanaka Kenji F.、Tsubota Kazuo
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 3422-3422
- DOI
  10.1038/s41598-019-39467-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H06062, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-16J03064, KAKENHI-PROJECT-16K11301
[Journal Article] Increased tear fluid production as a compensatory response to meibomian glandloss: a multicenter cross-sectional study．2015
- Author(s)
  Arita R，Morishige N，Koh S，Shirakawa S，Kawashima M，Sakimoto T，Suzuki T，Tsubota K
- Journal Title
  
  Ophthalmology
  
  Volume: 122 Pages: 925-933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462648
[Journal Article] Aerobic exercise increases tear secretion in type 2 diabetic mice.2014
- Author(s)
  Sano K, Kawashima M, Ito A, Inaba T, Morimoto K, Watanabe M, Tsubota K.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 55 Issue: 7 Pages: 4287-4294
- DOI
  10.1167/iovs.13-13289
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592651
[Presentation] 高脂肪食負荷した糖尿病モデルマウスにおける涙腺機能の解析2011
- Author(s)
  川島素子, 川北哲也, 稲葉隆明, 渡辺光博, 伊藤正孝, 榛村重人, 坪田一男
- Organizer
  角膜カンファランス2011第35回日本角膜学会総会/第27回日本角膜移植学会
- Place of Presentation
  東京
- Year and Date
  2011-02-17
- Data Source
  KAKENHI-PROJECT-22791691
[Presentation] 高脂肪食負荷した糖尿病モデルマウスにおける涙腺機能の解析2011
- Author(s)
  川島素子
- Organizer
  第35回日本角膜学会総会
- Place of Presentation
  品川プリンスホテル(東京)
- Year and Date
  2011-02-17
- Data Source
  KAKENHI-PROJECT-22791691
[Presentation] マイボーム腺機能不全患者において涙液水層は補償的に増加する-多施設横断研究-
- Author(s)
  有田玲子，森重直行，高静花，白川理香，川島素子，﨑元暢，鈴木崇，坪田一男
- Organizer
  角膜カンファランス2015
- Place of Presentation
  かるぽーと高知，高知市，高知県
- Year and Date
  2015-02-11 – 2015-02-13
- Data Source
  KAKENHI-PROJECT-26462648

1. TSUBOTA Kazuo (40163878)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. ITO Masataka (30534896)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. INOUE Sachiko (50338125)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SANO Kokoro

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. Arita Reiko (00338120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 松本幸裕 (70276434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 稲垣絵海 (40464903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 栗原俊英 (50365342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石田成弘

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 田中謙二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWASHIMA Motoko 川島 素子

川島 素子 カワシマ モトコ

Research Projects

Research Products

Co-Researchers

A novel prevention and treatment method of ocular aging by targeting sirtuins.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of tear secretion mechanism focus on environmental factorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical safety and efficacy of vitamin D3 analog ointment for treatment of obstructive meibomian gland dysfunction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

tear secretion and AMPKPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of decreased tear secretion in mice with metabolic syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of limbal melanocytes in interaction between limbal stem cells and melanocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

涙液産生におけるアクアポリン5の生理的役割の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Advances in the Diagnosis and Treatment of Dry Eye2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hydrogen-producing milk to prevent reduction in tear stability in persons using visual display terminals.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enriched environment alleviates stress-induced dry-eye through the BDNF axis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased tear fluid production as a compensatory response to meibomian glandloss: a multicenter cross-sectional study．2015

Author(s)

Journal Title

Data Source

[Journal Article] Aerobic exercise increases tear secretion in type 2 diabetic mice.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 高脂肪食負荷した糖尿病モデルマウスにおける涙腺機能の解析2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 高脂肪食負荷した糖尿病モデルマウスにおける涙腺機能の解析2011

Author(s)

Organizer

KAWASHIMA Motoko 川島素子

川島素子カワシマモトコ