YO Kikuo 葉季久雄

… Alternative Names

YOH Kikuo 葉季久雄

葉季久雄ヨウキクオ

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Researcher Number	00327644
Other IDs
Affiliation (based on the past Project Information) *help	2013 – 2014: 慶應義塾大学, 医学部, 共同研究員 2012: 慶應義塾大学, 医学部, 研究員 2011: 慶應義塾大学, 医学部, 共同研究員 2007: Keio University, School of Medicine, Instructor 2004 – 2006: Keio University, Department of Medicine, Instructor, 医学部, 助手 2001: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator General surgery / Emergency medicine Except Principal Investigator Emergency medicine / General surgery / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 褐色脂肪 / 褐色脂肪組織 / Hypermetabolism / Surgical metabolism / burn / sepsis / SIRS / Th2 chemokine Except Principal Investigator sepsis / SIRS … More / LPS / priming / 高体温 / ARDS / HGF / 高濃度酸素 / hyperoxia / TNF / protein C / 高温環境 / MDC / CCL22 / Sepsis / coagulation and fibrinolysis / cytokine / hypothermia / hyperthermia / インターロイキン12 / MAPキナーゼ / 好中球エラスターゼ / 凝固因子 / 熱傷 / インターロイキン18 / 敗血症 / 凝固線溶系 / サイトカイン / 低体温 / 熱中症 / survival / acidosis / tissue oxygen metabolism / fluid replacement / resuscitation / experimental model / hemorrhagic shock / 臓器障害 / 酸素代謝 / トノメーター / 血栓 / 外傷 / 出血モデル / ショック / 動脈血酸素分圧 / 生存率 / アシドーシス / 組織酸素代謝 / 輸液 / 蘇生 / 実験モデル / 出血性ショック Less

The mechanism of brown adipocyte by the surgical insult and the attenuation of hypermetabolismPrincipal Investigator
- Principal Investigator
  
  YO Kikuo
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Keio University
重症病態に対する能動的アプローチによる病態改善の試みPrincipal Investigator
- Principal Investigator
  
  葉季久雄
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Keio University
Immunological and metabolic changes induced by severe insults : insights into its pathophysiology and a development of new therapies
- Principal Investigator
  
  AIKAWA Naoki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Keio University
Analysis of altered immunological responses under abnormal environmental conditions, including environmental temperature, and the trial of its active modulation for the treatment of critically ill patients
- Principal Investigator
  
  AIKAWA Naoki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Keio University
An experimental study on hypotensive resuscitation of near-lethal uncontrolled hemorrhage : Effects on tissue dysoxia, mortality and end-organ function at 72 hours
- Principal Investigator
  
  AOKI Katsunori
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hamamatsu University School of Medicine
  Keio University

All 2013 2007 2006 2002

All Journal Article Presentation

[Journal Article] Brown adipose tissue and its modulation by a mitochondria-targeted peptide in rat burn injury-induced hypermetabolism2013
- Author(s)
  Yo K, Yu YM, Zhao G, Bonab AA, Aikawa N, Tompkins RG, Fischman AJ
- Journal Title
  
  Am J Physiol Endocrinol Metab.
  
  Volume: 304 Issue: 4 Pages: E331-E341
- DOI
  10.1152/ajpendo.00098.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791500
[Journal Article] 外科的侵襲後の感染性ショックによる急性肺傷害はIL-18の予防投与によって改善する2007
- Author(s)
  関根和彦, [葉季久雄], 他.
- Journal Title
  
  日本外科感染症学会雑誌 4
  
  Pages: 461-461
- Data Source
  KAKENHI-PROJECT-18791344
[Journal Article] Neutrophil elastase and systemic inflaminatory response syndrome in theinitiation and development of acute lung injury among critically m patients.2007
- Author(s)
  Fujishim a S, [Yoh K], et. al.
- Journal Title
  
  Biowd Pharmachother. (Epub) 62(5)
  
  Pages: 333-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18791344
[Journal Article] 重症患者における好中球エラスターゼ(NE)と肺傷害の発症、病態増悪2007
- Author(s)
  藤島清太郎, [葉季久雄], 他
- Journal Title
  
  日本外科感染症学会雑誌 4
  
  Pages: 461-461
- Data Source
  KAKENHI-PROJECT-18791344
[Journal Article] 高度侵襲下で発症したSepsisに対する早期輸液療法の生存率改善効果2006
- Author(s)
  葉季久雄
- Journal Title
  
  日本救急医学会雑誌 17(8)
  
  Pages: 385-385
- Data Source
  KAKENHI-PROJECT-18791344
[Journal Article] 分子生物学的研究と救急医療 BeadArrayシステムを用いた遺伝子発現の網羅的解析高度侵襲下病態解析への応用2006
- Author(s)
  藤島清太郎, [葉季久雄] 他
- Journal Title
  
  日本救急医学会雑誌 17(8)
  
  Pages: 344-344
- Data Source
  KAKENHI-PROJECT-18791344
[Journal Article] 救急患者におけるALI/ARDS病態と好中球エラスターゼ(NE)2006
- Author(s)
  藤島清太郎, [葉季久雄] 他
- Journal Title
  
  日本救急医学会雑誌 17(8)
  
  Pages: 395-395
- Data Source
  KAKENHI-PROJECT-18791344
[Journal Article] 熱傷負荷マウスにおけるTARCの動態2006
- Author(s)
  葉季久雄
- Journal Title
  
  熱傷 32(4)
  
  Pages: 235-235
- Data Source
  KAKENHI-PROJECT-18791344
[Journal Article] 熱傷マウスのCD4陽性Tリンパ球におけるCCR5の発現2006
- Author(s)
  関根和彦, [葉季久雄] 他
- Journal Title
  
  熱傷 32(4)
  
  Pages: 235-235
- Data Source
  KAKENHI-PROJECT-18791344
[Journal Article] 高度侵襲下で発症したSepsisに対する早期輸液療法の生存率改善効果2006
- Author(s)
  葉季久雄, [相川直樹]他
- Journal Title
  
  日本救急医学会雑誌 17
  
  Pages: 385-385
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Sentic ARDSの予防と対策基礎傷病に続発したseptic ALI/ARDSに対するsteroidの治療効果マウス熱傷後sepsisモデルによる検討2006
- Author(s)
  佐々木淳一, [葉季久雄] 他
- Journal Title
  
  日本外科感染症学会雑誌 3 (Suppl.)
  
  Pages: 400-400
- Data Source
  KAKENHI-PROJECT-18791344
[Journal Article] 重症熱傷患者における血流感染の予測因子の検討2006
- Author(s)
  葉季久雄, [相川直樹]他
- Journal Title
  
  日本外科感染症学会雑誌 3
  
  Pages: 458-458
- Data Source
  KAKENHI-PROJECT-17390482
[Journal Article] Total Burn Care ; Second.2002
- Author(s)
  Yohtaro Shinozawa, Naoki Aikawa
- Journal Title
  
  Edition. Renal failure in burned patients
  
  Pages: 393-398
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Journal Article] Use of antifungal agents in febrile patients nonresponsive to antibacterial treatment: the current status in surgical and critical care patients in Japan2002
- Author(s)
  Naoki Aikawa, Sumiyama Yoshinobu, et al.
- Journal Title
  
  Journal of infection and chemotherapy Vol.8, No2
  
  Pages: 237-241
- NAID
  10013892938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370364
[Presentation] 熱傷負荷マウスにおける細菌内毒素感受性2007
- Author(s)
  葉季久雄, 他
- Organizer
  日本熱傷学会
- Place of Presentation
  金沢市
- Year and Date
  2007-06-07
- Data Source
  KAKENHI-PROJECT-18791344

1. SEKINE Kazuhiko (90296715)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. AIKAWA Naoki (40110879)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. AOKI Katsunori (20124927)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. HORI Shingo (80129650)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. FUJISHIMA Seitaro (00173419)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NISHINA Masayoshi (20180622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MIYAKI Masaru (60365400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 並木淳 (20189195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山崎元靖 (00296716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YO Kikuo 葉 季久雄

YOH Kikuo 葉 季久雄

葉 季久雄 ヨウ キクオ

Research Projects

Research Products

Co-Researchers

The mechanism of brown adipocyte by the surgical insult and the attenuation of hypermetabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

重症病態に対する能動的アプローチによる病態改善の試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunological and metabolic changes induced by severe insults : insights into its pathophysiology and a development of new therapies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of altered immunological responses under abnormal environmental conditions, including environmental temperature, and the trial of its active modulation for the treatment of critically ill patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An experimental study on hypotensive resuscitation of near-lethal uncontrolled hemorrhage : Effects on tissue dysoxia, mortality and end-organ function at 72 hours

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Brown adipose tissue and its modulation by a mitochondria-targeted peptide in rat burn injury-induced hypermetabolism2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 外科的侵襲後の感染性ショックによる急性肺傷害はIL-18の予防投与によって改善する2007

Author(s)

Journal Title

Data Source

[Journal Article] Neutrophil elastase and systemic inflaminatory response syndrome in theinitiation and development of acute lung injury among critically m patients.2007

Author(s)

Journal Title

Data Source

[Journal Article] 重症患者における好中球エラスターゼ(NE)と肺傷害の発症、病態増悪2007

Author(s)

Journal Title

Data Source

[Journal Article] 高度侵襲下で発症したSepsisに対する早期輸液療法の生存率改善効果2006

Author(s)

Journal Title

Data Source

[Journal Article] 分子生物学的研究と救急医療 BeadArrayシステムを用いた遺伝子発現の網羅的解析 高度侵襲下病態解析への応用2006

Author(s)

Journal Title

Data Source

[Journal Article] 救急患者におけるALI/ARDS病態と好中球エラスターゼ(NE)2006

Author(s)

Journal Title

Data Source

[Journal Article] 熱傷負荷マウスにおけるTARCの動態2006

Author(s)

Journal Title

Data Source

[Journal Article] 熱傷マウスのCD4陽性Tリンパ球におけるCCR5の発現2006

Author(s)

Journal Title

Data Source

[Journal Article] 高度侵襲下で発症したSepsisに対する早期輸液療法の生存率改善効果2006

Author(s)

Journal Title

Data Source

[Journal Article] Sentic ARDSの予防と対策 基礎傷病に続発したseptic ALI/ARDSに対するsteroidの治療効果 マウス熱傷後sepsisモデルによる検討2006

Author(s)

Journal Title

YO Kikuo 葉季久雄

YOH Kikuo 葉季久雄

葉季久雄ヨウキクオ

[Journal Article] 分子生物学的研究と救急医療 BeadArrayシステムを用いた遺伝子発現の網羅的解析高度侵襲下病態解析への応用2006

[Journal Article] Sentic ARDSの予防と対策基礎傷病に続発したseptic ALI/ARDSに対するsteroidの治療効果マウス熱傷後sepsisモデルによる検討2006