Kojima Yutaka 小島豊

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Kojima yutaka 小島豊

kojima yutaka 小島豊

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Researcher Number	00327800
Affiliation (Current)	2025: 順天堂大学, 医学部, 客員准教授
Affiliation (based on the past Project Information) *help	2021 – 2022: 順天堂大学, 医学部, 客員准教授 2020: 順天堂大学, 医学部, 先任准教授 2016 – 2018: 順天堂大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery
Keywords	Principal Investigator 癌微小環境 / 大腸癌 / CAFｓ / CAFs / 原発巣由来転移抑制因子 / 転移ニッチ / 転移抑制シグナル / 原発巣 / 大腸癌オルガノイド / オルガノイド … More / PDXモデル / 転移 / 線維芽細胞 / トランスレーショナルリサーチ / 癌 / Niche / Metastatic dormancy / niche / tumor microenvironment / metastatic dormancy Less

Elucidation of the metastasis suppression signal mechanism derived from the primary lesion of colorectal cancerPrincipal Investigator
- Principal Investigator
  
  Kojima yutaka
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Juntendo University
Dissection of molecular mechanisms of the metastatic niche dormancy and application to the ant-metastatic therapyPrincipal Investigator
- Principal Investigator
  
  kojima yutaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Juntendo University

All 2021 2019 2018 2017

All Journal Article Presentation

[Journal Article] Significance of postoperative adjuvant chemotherapy with an oxaliplatin-based regimen after simultaneous curative resection for colorectal cancer and synchronous colorectal liver metastasis: a propensity score matching analysis2021
- Author(s)
  Sugimoto K, Sakamoto K, Ii Y, Amemiya K, Sugo H, Ito T, Munakata S, Takahashi M, Kojima Y, Tomiki Y, Sato K, Saiura A, Kawasaki S.
- Journal Title
  
  BMC Surg.
  
  Volume: 21 Issue: 1 Pages: 1-9
- DOI
  10.1186/s12893-021-01193-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09111
[Journal Article] Metastatic seeding of human colon cancer cell clusters expressing the hybrid epithelial/mesenchymal state.2019
- Author(s)
  Mizukoshi K, Okazawa Y, Haeno H, Koyama Y, Sulidan K, Komiyama H, Saeki H, Ohtsuji N, Ito Y, Kojima Y, Goto M, Habu S, Hino O, Sakamoto K, Orimo A.
- Journal Title
  
  Int J Cancer
  
  Volume: 146 Issue: 9 Pages: 2547-2562
- DOI
  10.1002/ijc.32672
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-17K10653, KAKENHI-PROJECT-18K07207, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-16K08974, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-16K15598, KAKENHI-PROJECT-20K09111, KAKENHI-PROJECT-20K16367, KAKENHI-PROJECT-20K17664
[Journal Article] High-sensitivity detection of micrometastases generated by GFP lentivirus-transduced　organoids cultured from a patient-derived colon tumor.2018
- Author(s)
  OkazawaY, Mizukoshi K, KoyamaY, Okubo S, Komiyama H, Kojima Y, Goto M, Habu S, Hino O, Sakamoto K, Orimo A.
- Journal Title
  
  J Vis Exp
  
  Volume: 136(e57374) Issue: 136 Pages: 463-473
- DOI
  10.3791/57374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-17K10653, KAKENHI-PROJECT-18K07207, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-16K15598, KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-16K15625
[Journal Article] Endoscopic Submucosal Dissection Decreases Additional Colorectal Resection for T1 Colorectal Cancer.2018
- Author(s)
  Tomiki Y, Kawai M, Kawano S, Ishiyama S, Sugimoto K, Takahashi M, Kojima Y, Murakami T, Ritsuno H, Shibuya T, Sakamoto N, Sakamoto K.
- Journal Title
  
  Medical Science Monitor
  
  Volume: 24 Pages: 6910-6917
- DOI
  10.12659/msm.909380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-16K15625
[Journal Article] Pharmacological targeting of neutrophil serine proteases prevents lethality in dextran sulfate　sodium (DSS)-induced colitis in mice2018
- Author(s)
  Ro H, Munakata S, Ueyama T, Komiyama H, Takahashi M, Kojima Y, Tomiki Y, Sakamoto K
- Journal Title
  
  Journal of Gastrointestinal & Digestive System
  
  Volume: 8 Issue: 01 Pages: 551-551
- DOI
  10.4172/2161-069x.1000551
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-16K08974, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-17K10653, KAKENHI-PROJECT-16K15598, KAKENHI-PROJECT-16K15625, KAKENHI-PROJECT-26462025, KAKENHI-PROJECT-16K19956, KAKENHI-PROJECT-18K08798
[Journal Article] Case report of perineal hernia after laparoscopic abdominoperineal resection.2018
- Author(s)
  Honjo K, Sakamoto K, Motegi S, Tsukamoto R, Munakata S, Sugimoto K, Kamiyama H, Takahashi M, Kojima Y, Fukunaga T, Kajiyama Y, Kawasaki S
- Journal Title
  
  Asian journal of endoscopic surgery
  
  Volume: 11 Issue: 2 Pages: 173-176
- DOI
  10.1111/ases.12420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15625
[Journal Article] Minimally Invasive Surgery for Colorectal Cancer2017
- Author(s)
  Sakamoto K, Tsukamoto R, Kawano S, Kawai M, Niwa K, Ishiyama S, Sugimoto K, Kamiyama H, Komiyama H, Takahashi M, Kojima Y, Goto M, Okuzawa A, Tomiki Y:
- Journal Title
  
  Juntendo Medical Journal
  
  Volume: 63 Issue: 5 Pages: 384-392
- DOI
  10.14789/jmj.63.384
- NAID
  130006219695
- ISSN
  2187-9737, 2188-2126
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-16K08974, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-16K15625
[Journal Article] LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer2017
- Author(s)
  Jotatsu, T., Yagishita, S., Tajima, K., Takahashi, F., Mogushi, K., Hidayat, M., Wirawan, A., Ko, R., Kanemaru, R., Shimada, N., Mitani, K., Saito, T., Takamochi, K., Suzuki, K., Kohsaka, S., Kojima, S., Mukae, H., Yatera, K., and Takahashi, K.
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: ９ Pages: 86-94
- DOI
  10.1016/j.bbrep.2016.11.015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09586, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-16K15625
[Journal Article] Propensity Score Analysis in the Comparison of Long-Term Outcomes for Locally Advanced Colon Cancer Between Laparoscopic Colectomy and Open Colectomy2017
- Author(s)
  Sugimoto K, Sakamoto K, Ichikawa R, Kure K, Honjo K, Ro H, Takahashi R, Kawano, Niwa K, Ishiyama S, Kamiyama H, Komiyama H, Takahashi M, Kojima Y, Goto M, Okuzawa A, Ishibiki Y, Tomiki Y
- Journal Title
  
  Juntendo Medical Journal
  
  Volume: 63 Issue: 4 Pages: 264-272
- DOI
  10.14789/jmj.63.264
- NAID
  130006106309
- ISSN
  2187-9737, 2188-2126
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-17K10653, KAKENHI-PROJECT-16K15598, KAKENHI-PROJECT-16K15625
[Journal Article] Superior mesenteric artery syndrome improved by enteral nutritional therapy according to the ｃontrolling nuritional status score.2017
- Author(s)
  Takehara K, Sakamoto K, Takahashi R, Kawai M, Kawano S, Munakata S, Sugimoto K, Takahashi M, Kojima Y, Fukunaga T, Kajiyama Y, Kawasaki S:
- Journal Title
  
  Case Reports in Gastroenterology
  
  Volume: 11(3) Issue: 3 Pages: 721-727
- DOI
  10.1159/000484129
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-16K15625
[Journal Article] Salivary Chromogranin A as a Psychosomatic Stress Marker Is Suppressed in Laparoscopic Surgery Compared with Open Surgery for Colon Cancer2017
- Author(s)
  Ishiyama　S, Sakamoto　K, Kamiyama　H,　Niwa　K, Sugimoto　K, Takahashi　M, KojimaY, Goto M, Okuzawa A, Tomiki Y:
- Journal Title
  
  Juntendo Medical Journal
  
  Volume: 63 Issue: 2 Pages: 88-94
- DOI
  10.14789/jmj.63.88
- NAID
  130006944480
- ISSN
  2187-9737, 2188-2126
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-16K08974, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-16K15625
[Presentation] 中間型上皮間葉移行による患者大腸癌細胞クラスターの転移への寄与2018
- Author(s)
  岡澤裕、水越幸輔、小山侑、大久保捷奇、Kaidiliavi Sulidan、伊藤恭彦、小見山博光、小島豊、五藤倫敏、垣生園子、樋野興夫、折茂彰、坂本一博
- Organizer
  第29回日本消化器癌発生学会総会　東京
- Data Source
  KAKENHI-PROJECT-16K15625
[Presentation] Postoperative adjuvant chemotherapy improves survival in stage II colon cancer ? a propensity score matching analysis.2017
- Author(s)
  Tsukamoto R, Matsuzawa M, Hagiwara T, Tsuchiya Y, Amemiya K, Motegi S, Makino Y, Kawano S, Honjo K, Kure K, Ichikawa R, Ro H, Ito S, Takahashi R, Niwa K, Ishiyama S, Sugimoto K, Kamiyama H, Takahashi M, Kojima Y, Goto M, Okuzawa A, Tomiki Y, Fukunaga T, Kajiyama Y, Kawasaki S, Sakamoto K:
- Organizer
  110th AACR, Washington DC
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15625
[Presentation] 大腸癌術後の再発に対して複合的免疫細胞療法(全身化学療法/免疫細胞療法併用)を施行した2例.2017
- Author(s)
  杉本起一, 土谷祐樹, 松澤宏和, 本庄薫平, 河合雅也, 宗像慎也, 丹羽浩一郎, 石山隼, 神山博彦, 高橋玄, 小島豊, 後藤重則, 瀧本理修, 神垣隆, 坂本一博.
- Organizer
  第55回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15625
[Presentation] Semaphorin 3C has a possibility of a new prognostic marker in colorectal cancer.2017
- Author(s)
  Kawano S, Komiyama H, Kojima Y, Sakamoto K et al.
- Organizer
  110th AACR, Washington DC,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15625

1. 折茂彰 (70275866)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 小見山博光 (30348982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. MOGUSHI Kaoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 坂本一博

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
5. 高橋和久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 高橋史行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 田島健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 高橋玄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kojima Yutaka 小島 豊

Kojima yutaka 小島 豊

kojima yutaka 小島 豊

Research Projects

Research Products

Co-Researchers

Elucidation of the metastasis suppression signal mechanism derived from the primary lesion of colorectal cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dissection of molecular mechanisms of the metastatic niche dormancy and application to the ant-metastatic therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Significance of postoperative adjuvant chemotherapy with an oxaliplatin-based regimen after simultaneous curative resection for colorectal cancer and synchronous colorectal liver metastasis: a propensity score matching analysis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metastatic seeding of human colon cancer cell clusters expressing the hybrid epithelial/mesenchymal state.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High-sensitivity detection of micrometastases generated by GFP lentivirus-transduced organoids cultured from a patient-derived colon tumor.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endoscopic Submucosal Dissection Decreases Additional Colorectal Resection for T1 Colorectal Cancer.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pharmacological targeting of neutrophil serine proteases prevents lethality in dextran sulfate sodium (DSS)-induced colitis in mice2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Case report of perineal hernia after laparoscopic abdominoperineal resection.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Minimally Invasive Surgery for Colorectal Cancer2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Propensity Score Analysis in the Comparison of Long-Term Outcomes for Locally Advanced Colon Cancer Between Laparoscopic Colectomy and Open Colectomy2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Superior mesenteric artery syndrome improved by enteral nutritional therapy according to the ｃontrolling nuritional status score.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Salivary Chromogranin A as a Psychosomatic Stress Marker Is Suppressed in Laparoscopic Surgery Compared with Open Surgery for Colon Cancer2017

Author(s)

Journal Title

DOI

NAID

ISSN

Kojima Yutaka 小島豊

Kojima yutaka 小島豊

kojima yutaka 小島豊

[Journal Article] High-sensitivity detection of micrometastases generated by GFP lentivirus-transduced　organoids cultured from a patient-derived colon tumor.2018

[Journal Article] Pharmacological targeting of neutrophil serine proteases prevents lethality in dextran sulfate　sodium (DSS)-induced colitis in mice2018