KITAJIMA Keiko 北島桂子

… Alternative Names

北島桂子キタジマケイコ

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Researcher Number	00332784
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 助教
Affiliation (based on the past Project Information) *help	2025: 九州大学, 医学研究院, 助教 2016 – 2023: 九州大学, 医学研究院, 助教 2014 – 2015: 九州大学, 医学(系)研究科(研究院), 助教 2013: 九州大学, 医学研究院, 助教 2003 – 2005: Shimane University School of Medicine, Dept. of Environmental Preventive Medicine, Assistant Professor, 医学部, 助手 2001 – 2002: 島根医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Embryonic/Neonatal medicine / Hygiene Except Principal Investigator Developmental biology / Public health/Health science / 寄生虫学(含医用動物学) / Biological Sciences
Keywords	Principal Investigator マウス初期胚 / 左右軸 / 糖尿病 / Wntシグナル / 左右軸形成 / 高血糖 / 妊娠糖尿病 / CRISPR-Cas9 / 原始結節 / マウス胚 … More / Nodalシグナル / 体軸形成 / 心臓発生 / 糖尿病母体 / 先天異常 / 血糖値改善効果 / 運動負荷 / 肥満マウス / インスリン抵抗性 … More Except Principal Investigator 左右軸形成 / ソフトウェア / 次世代シークエンス / ChIPシークエンス / 発生・分化 / 胚発生 / データーベース / 遺伝子発現 / ChIP-seq / データベース / 左右軸 / Mongolians / Koreans / Japanese / life style / Asian / β_3-adrenergic receptor / metabolic syndrome / obesity / 高血圧 / インスリン抵抗性 / 高脂血症 / 遺伝子多型 / β3アドレナリン受容体 / 日本 / 韓国 / モンゴル / アジア / 肥満改善プログラム / 食習慣 / 代謝症候群 / 内臓脂肪型肥満 / Diphyllobothrlum yonagoense / Sparganosis / Larva migrans / Diplogonoporus grandis / Diphyllobothrium nihonkaiense / International Research Network / Dphyllobothriasis / Cestode Infection / 米子裂頭条虫 / マンソン孤虫症 / マンソン幼虫移行症 / 大複殖門条虫 / 日本海裂頭条虫 / 国際研究ネットワーク / 裂頭条虫症 / 条虫症 / ダウンレギュレーション / リソソーム / 細胞シグナル / オルガネラ酸性化 / Wntシグナル / 小胞輸送 / エンドサイトーシス / 多能性幹細胞 / 原腸胚形成 / 細胞外シグナル Less

糖尿病母体環境が引き起こす先天異常に関するWntシグナルの解析Principal Investigator
- Principal Investigator
  
  北島桂子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyushu University
胎児の左右軸形成異常を引き起こす糖尿病母胎環境と分子メカニズムの解析Principal Investigator
- Principal Investigator
  
  北島桂子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyushu University
Molecular mechanisms of the fetal left-right axis malformations induced by maternal hyperglycemia.Principal Investigator
- Principal Investigator
  
  Kitajima Keiko
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyushu University
Molecular mechanisms of the left-right axis malformations in pregnancy hyperglycemiaPrincipal Investigator
- Principal Investigator
  
  Kitajima Keiko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Kyushu University
Analysis of molecular mechanism for initial left-right axis formation in the node of mouse embryos
- Principal Investigator
  
  Chikara Meno
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  Kyushu University
Analysis of exracellular signal in cell community of early embryos
- Principal Investigator
  
  MENO Chikara
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
運動によるインスリン抵抗性改善に関わる筋由来遺伝子群のプロファイリングと機能解析Principal Investigator
- Principal Investigator
  
  北島桂子
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hygiene
- Research Institution
  Shimane University
The relationship between genetic polymorphism and lifestyle for visceral obesity
- Principal Investigator
  
  SHIWAKU Kuninori
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Public health/Health science
- Research Institution
  Shimane University (School of Medicine)
The taxonomical, epidemiological, and ecological studies of human diphyllobothriasis in the international collaboration with research networks
- Principal Investigator
  
  YAMANE Yosuke
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Shimane University School of Medicine

All 2020 2019 2017 2016 2015 2013 2012 2010 Other

All Journal Article Presentation

[Journal Article] Expression of leukotriene B4 receptor 1 defines functionally distinct DCs that control allergic skin inflammation.2020
- Author(s)
  Tomoaki Koga, Fumiyuki Sasaki, Kazuko Saeki, Soken Tsuchiya, Toshiaki Okuno, Mai Ohba, Takako Ichiki, Satoshi Iwamoto, Hirotsugu Uzawa, Keiko Kitajima, Chikara Meno, Eri Nakamura, Norihiro Tada, Yoshinori Fukui, Junichi Kikuta, Masaru Ishii, Yukihiko Sugimoto, and Mitsuyoshi Nakao, Takehiko Yokomizo.
- Journal Title
  
  Cellular & Molecular Immunology
  
  Volume: 8 Issue: 6 Pages: 1-13
- DOI
  10.1038/s41423-020-00559-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05691, KAKENHI-PROJECT-18K06923, KAKENHI-PROJECT-18K07880, KAKENHI-PROJECT-19K07357, KAKENHI-PROJECT-19K22503, KAKENHI-PROJECT-17H01571, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-18H02618, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-19H00983, KAKENHI-PROJECT-21H04798, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-20K07328, KAKENHI-PROJECT-19KK0199, KAKENHI-PROJECT-20KK0185
[Journal Article] Leukotriene B4 receptor type 2 (BLT2) enhances skin barrier function by regulating tight junction proteins.2016
- Author(s)
  Ishii Y, Saeki K, Liu M, Sasaki F, Koga T, Kitajima K, Meno C, Okuno T, Yokomizo T
- Journal Title
  
  FASEB J
  
  Volume: 30 Issue: 2 Pages: 933-947
- DOI
  10.1096/fj.15-279653
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08316, KAKENHI-PROJECT-26461637, KAKENHI-PROJECT-15K19032, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-ORGANIZER-22116001, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-25460374, KAKENHI-PROJECT-26291051, KAKENHI-PROJECT-16K08596, KAKENHI-PROJECT-15KK0320
[Journal Article] Hyperglycemia impairs left-right axis formation and thereby disturbs heart morphogenesis in mouse embryos.2015
- Author(s)
  Hachisuga M, Oki S, Kitajima K, Ikuta S, Sumi T, Kato K, Wake N, Meno C.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 112 Issue: 38 Pages: 5300-5307
- DOI
  10.1073/pnas.1504529112
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461637, KAKENHI-PROJECT-15K15608, KAKENHI-PUBLICLY-15H01517, KAKENHI-PROJECT-25670491, KAKENHI-PROJECT-25840087, KAKENHI-PROJECT-26291051
[Journal Article] Wnt signaling regulates left-right axis formation in the node of mouse embryos2013
- Author(s)
  Kitajima, Oki, Ohkawa, Sumi, Meno
- Journal Title
  
  Dev Biol
  
  Volume: 380 Issue: 2 Pages: 222-32
- DOI
  10.1016/j.ydbio.2013.05.011
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21116002, KAKENHI-PROJECT-23310134, KAKENHI-PROJECT-23570233, KAKENHI-PROJECT-23770254, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-25670491, KAKENHI-PROJECT-25840087
[Journal Article] Epiblast ground state is controlled by canonical Wnt/ β-catenin signaling in the postimplantation mouse embryo and epiblast stem cells2013
- Author(s)
  Sumi, Oki, Kitajima, Meno
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 5 Pages: e63378-e63378
- DOI
  10.1371/journal.pone.0063378
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21116002, KAKENHI-PROJECT-23570233, KAKENHI-PROJECT-23770254, KAKENHI-PROJECT-25670491, KAKENHI-PROJECT-25840087
[Journal Article] Restriction of Wnt signaling in the dorsal otocyst determines semicircular canal formation in the mouse embryo2012
- Author(s)
  T.Noda, et al
- Journal Title
  
  Developmental Biology
  
  Volume: 362 Issue: 1 Pages: 83-93
- DOI
  10.1016/j.ydbio.2011.11.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J01348, KAKENHI-PLANNED-21116002, KAKENHI-PROJECT-23770254
[Journal Article] Dissecting the role of Fgf signaling during gastrulation and left-right axis formation in mouse embryos using chemical inhibitors2010
- Author(s)
  Oki, Kitajima, Meno
- Journal Title
  
  Dev Dyn
  
  Volume: 239 Issue: 6 Pages: 1768-1778
- DOI
  10.1002/dvdy.22282
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21116002
[Presentation] Sox17 expression in the endocardium precursor cells regulates the mouse heart development2019
- Author(s)
  Rie Saba, Keiko Kitajima, Yasuinori Shintani, Yoshiakira Kanai, Masami Kanai-Azuma, Chikara Meno, Rumiko Saga, Ken Suzuki, Shigeru Miyagawa, Yoshiki Sawa, Hideya Yamazaki, Kei Yamada, Kenta Yasuhiro
- Organizer
  日本分子生物学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07880
[Presentation] 高血糖がマウス胚の左右軸形成に及ぼす影響2017
- Author(s)
  目野主税、蜂須賀正紘、鄒兆南、沖真弥、北島桂子
- Organizer
  日本先天異常学会
- Data Source
  KAKENHI-PROJECT-26461637
[Presentation] 妊娠前糖尿病における左右軸形成異常2016
- Author(s)
  蜂須賀正紘、北島桂子、沖真弥、生田智美、目野主税
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-26291051
[Presentation] Wnt signaling regulates the left-right axis formation in the node of mouse embyors2013
- Author(s)
  Keiko Kitajima, Shinya Oki, Tomoyuki Sumi, Chikara Meno
- Organizer
  第46回発生生物学会
- Place of Presentation
  松江
- Data Source
  KAKENHI-PLANNED-21116002
[Presentation] Wnt signaling regulates the left-right axis formation in the node2013
- Author(s)
  Kitajima, Oki, Sumi, Meno
- Organizer
  Mouse Molecular Genetics
- Place of Presentation
  Cambridge, UK
- Data Source
  KAKENHI-PLANNED-21116002
[Presentation] Wnt signaling regulates the left-right axis formation in the node of mouse embryos2013
- Author(s)
  Kitajima, Oki, Sumi, Meno
- Organizer
  第46回発生生物学会
- Place of Presentation
  松江
- Data Source
  KAKENHI-PLANNED-21116002
[Presentation] 高血糖症はマウス胚の左右軸形成を阻害することで心臓形態形成を撹乱する
- Author(s)
  蜂須賀正紘、沖真弥、北島桂子、角智行、目野主税
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26291051
[Presentation] 高血糖症はマウス胚の左右軸形成を阻害することで心臓形態形成を撹乱する
- Author(s)
  蜂須賀正紘、沖真弥、北島桂子、角智行、目野主税
- Organizer
  日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26461637

1. MENO Chikara (20311764)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. OKI Shinya (90452713)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. SHIWAKU Kuninori (10108384)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. WADA Yoh (50212329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAMANE Yosuke (60032182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SHIMONO Kumiko (30346382)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OHKAWA Yasuyuki (80448430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 佐伯和子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 多田昇弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KITAJIMA Keiko 北島 桂子

北島 桂子 キタジマ ケイコ

Research Projects

Research Products

Co-Researchers

糖尿病母体環境が引き起こす先天異常に関するWntシグナルの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

胎児の左右軸形成異常を引き起こす糖尿病母胎環境と分子メカニズムの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of the fetal left-right axis malformations induced by maternal hyperglycemia.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of the left-right axis malformations in pregnancy hyperglycemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of molecular mechanism for initial left-right axis formation in the node of mouse embryos

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of exracellular signal in cell community of early embryos

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

運動によるインスリン抵抗性改善に関わる筋由来遺伝子群のプロファイリングと機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The relationship between genetic polymorphism and lifestyle for visceral obesity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The taxonomical, epidemiological, and ecological studies of human diphyllobothriasis in the international collaboration with research networks

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Expression of leukotriene B4 receptor 1 defines functionally distinct DCs that control allergic skin inflammation.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Leukotriene B4 receptor type 2 (BLT2) enhances skin barrier function by regulating tight junction proteins.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hyperglycemia impairs left-right axis formation and thereby disturbs heart morphogenesis in mouse embryos.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Wnt signaling regulates left-right axis formation in the node of mouse embryos2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epiblast ground state is controlled by canonical Wnt/ β-catenin signaling in the postimplantation mouse embryo and epiblast stem cells2013

KITAJIMA Keiko 北島桂子

北島桂子キタジマケイコ