AIZAKI Hideki 相崎英樹

… Alternative Names

Hideki Aizaki 相崎英樹

相崎英樹アイザキヒデキ

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Researcher Number	00333360
Other IDs	https://orcid.org/0000-0002-8346-4729
Affiliation (Current)	2026: 国立健康危機管理研究機構, 国立感染症研究所ウイルス第二部, 室長
Affiliation (based on the past Project Information) *help	2026: 国立健康危機管理研究機構, 国立感染症研究所ウイルス第二部, 室長 2025: 国立健康危機管理研究機構, ウイルス第二部, 室長 2021 – 2024: 国立感染症研究所, ウイルス第二部, 室長 2015 – 2018: 国立感染症研究所, ウイルス第二部, 室長 2013 – 2015: 国立感染症研究所, その他部局等, その他 … More 2010 – 2013: 国立感染症研究所, ウイルス第二部, 室長 2012: 国立感染症研究所, ウイルス第2部, 室長 2006 – 2009: 国立感染症研究所, ウイルス第二部, 主任研究官 2007: 国立感染研究所, ウイルス第二部, 主任研究官 2002: 感染研, 研究員 2001: 国立感染症研究所, ウイルス第二部, 主任研究官 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Virology Except Principal Investigator Gastroenterology / Biological Sciences / Basic Section 49060:Virology-related
Keywords	Principal Investigator C型肝炎ウイルス / 複製複合体 / DMV / 複製 / プラス鎖RNAウイルス / double membrane vesicle / HSD13 / HSD11 / サブゲノミックレプリコン / NS5A … More / doble membrane vesicle / 新型コロナウイル / 小包膜 / 新型コロナウイルス / 小胞輸送 / 宿主因子 / Replication / Surf4 / 膜小胞 / SURF4 / Double membrane vesicle / HCV / 翻訳・複製調節 / プロテオーム / 内科 / 癌 / 感染症 / ウイルス / NS5B蛋白 / 分子シャペロン / 界面活性剤不溶性膜分画 / サブゲノムレプリ / 脂質ラフト / 界面性剤不溶性膜分画 / creatine kinase B / レプリコン / プロテオミックス / ウイルス様粒子 / 免疫電顕 / 感染性クローン / 肝細胞 / 3次元培養系 … More Except Principal Investigator HCV / 感染実験 / ウイルス / コレステロール / ウイルス複製 / 肝発がん / ポリコム抑制複合体１ / Ｃ型肝炎ウイルス / C型肝炎 / C型肝炎ウイルス(HCV) / C型肝炎ウイルス / コラーゲン / キメラマウス / 肝硬変 / TGF-β受容体 / NS3 / C型肝炎ウイルス（HCV） / 脂質ラフト / 脂肪滴 / レセプター / 宿主因子 / ラフト / スフィンゴ脂質 / インターフェロン / 肝細胞 / 遺伝子導入 Less

プラス鎖RNAウイルス複製に必要な膜小胞の形成メカニズムの解析Principal Investigator
- Principal Investigator
  
  相崎英樹
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Japan Institute for Health Security
Study of the mechanism of PRC1-targeting genes in hepatitis C virus-infected liver
- Principal Investigator
  
  森石恆司
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  University of Yamanashi
Analysis of the mechanism of membrane vesicle formation required for the replication of hepatitis C virus and novel coronavirusPrincipal Investigator
- Principal Investigator
  
  Hideki Aizaki
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  National Institute of Infectious Diseases
Analysis of the replication mechanism of hepatitis C virus in membrane vesicles containing replication complexesPrincipal Investigator
- Principal Investigator
  
  Hideki Aizaki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  National Institute of Infectious Diseases
Detection of host factors involved in active HCV replication complexPrincipal Investigator
- Principal Investigator
  
  Aizaki Hideki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  National Institute of Infectious Diseases
Studies on a role of TGF-beta mimetic activity of HCV NS3 protease in pathogenesis of liver cirrhosis
- Principal Investigator
  
  KOJIMA SOICHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The Institute of Physical and Chemical Research
C型肝炎ウイルスの感染増殖および粒子形成における脂質の役割
- Principal Investigator
  
  脇田隆字
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases
Identification of molecular chaperones as regulators for HCV RNA replication through proteomics approachesPrincipal Investigator
- Principal Investigator
  
  AIZAKI Hideki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  National Institute of Infectious Diseases
Analysis of the role of lipid in viral life cycles
- Principal Investigator
  
  WAKITA Taksji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases
C型肝炎ウイルス複製に関与する宿主因子の同定とウイルス複製機構の解析Principal Investigator
- Principal Investigator
  
  相崎英樹
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  National Institute of Infectious Diseases
C型肝炎ウイルスの感染初期過程に関与する宿主因子の探索
- Principal Investigator
  
  脇田隆字
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  National Institute of Infectious Diseases
感染性C型肝炎ウイルス粒子による肝細胞への遺伝子デリバリーシステムの構築
- Principal Investigator
  
  WAKITA Takaji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases
Analysis of factors involved in viral replication efficiency and search for novel anti -virals using HCV culture systems.
- Principal Investigator
  
  WAKITA Takaji
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  National Institute of Infectious Diseases
肝細胞三次元培養系から得られたC型肝炎ウイルス粒子の性状解析Principal Investigator
- Principal Investigator
  
  相崎英樹
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases

[Book] ウイルス性肝炎発見の歴史、ウイルス性肝炎学2023―最新の病態・診断・治療―2023
- Author(s)
  相崎英樹、溝上雅史、脇田隆字
- Total Pages
  5
- Publisher
  日本臨床社、東京
- Data Source
  KAKENHI-PROJECT-21K07974
[Book] 日本の感染症―明らかにされたこと残された課題2022
- Author(s)
  相崎英樹
- Total Pages
  22
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-21K07974
[Book] 臨床消化器内科Vol.37 No.92022
- Author(s)
  相崎英樹、青柳東代、杉山真也、村松正道、溝上雅史、脇田隆字
- Total Pages
  6
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-21K07974
[Book] C型肝炎のウイルス学と病態、C型肝疾患の今後の課題―肝炎、肝硬変、肝がん―2021
- Author(s)
  青柳東代、村松正道、脇田隆字、相崎英樹
- Total Pages
  8
- Publisher
  消化器内科
- Data Source
  KAKENHI-PROJECT-21K07974
[Book] Ｃ型肝炎ウイルスの感染増殖と病原性発現メカニズム、創薬研究者がこれだけは知っておきたい最新のウイルス学2021
- Author(s)
  相崎英樹
- Total Pages
  9
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-21K07974
[Book] C型肝炎ウイルスの遺伝子構造と抗ウイルス薬の作用機序は？2018
- Author(s)
  52.相崎英樹
- Total Pages
  1
- Publisher
  日本医事新報
- Data Source
  KAKENHI-PROJECT-15K09034
[Book] ここまでわかったC型肝炎ウイルスの感染・複製機構、目覚しく治療効果を発揮するC型肝炎治療2017
- Author(s)
  相崎英樹、和気健二郎、脇田隆字
- Total Pages
  10
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-15K09034
[Book] Mebio2017
- Author(s)
  相崎英樹、和気健二郎、脇田隆字
- Total Pages
  10
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-15K09034
[Book] 特集ウイルス肝炎のすべて、医学のあゆみ2017
- Author(s)
  4.相崎英樹、Zheng Xin、脇田隆字
- Total Pages
  6
- Publisher
  医歯薬出版社
- Data Source
  KAKENHI-PROJECT-15K09034
[Book] くらしの豆知識2016
- Author(s)
  相崎英樹、脇田隆字
- Total Pages
  2
- Publisher
  国民生活センター
- Data Source
  KAKENHI-PROJECT-15K09034
[Book] 肝炎ウイルス検査のすすめ；身近にひそむ危険を防ぐ2016
- Author(s)
  相崎英樹、脇田隆字
- Total Pages
  2
- Publisher
  国民生活センター
- Data Source
  KAKENHI-PROJECT-24591001
[Book] 肝炎ウイルス検査のすすめ2016
- Author(s)
  相崎英樹、脇田隆字
- Total Pages
  2
- Publisher
  国民生活センター
- Data Source
  KAKENHI-PROJECT-15K09034
[Book] C型肝炎治療における新時代の幕開け、C型肝炎ウイルスの複製・増殖のメカニズム2016
- Author(s)
  相崎英樹、脇田隆字
- Total Pages
  4
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-24591001
[Book] 医薬ジャーナル2016
- Author(s)
  相崎英樹、脇田隆字
- Total Pages
  4
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-15K09034
[Book] C型肝炎ウイルスの複製・増殖のメカニズム、特集C型肝炎治療における新時代の幕開け、特集C型肝炎治療における新時代の幕開け2015
- Author(s)
  相崎英樹、脇田隆字
- Total Pages
  4
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-15K09034
[Book] 日本におけるC型肝炎の疫学国際比較、真ウイルス性肝炎学―最新の基礎・臨床研究情報―2015
- Author(s)
  田中純子、相崎英樹、内田茂治
- Total Pages
  9
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-15K09034
[Book] HCV研究の最先端,HCV感染実験系における代謝変化.2014
- Author(s)
  相崎英樹,松田麻未,藤本陽,脇田隆字.
- Total Pages
  4
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-24591001
[Book] 医学のあゆみ2013
- Author(s)
  相崎英樹
- Total Pages
  2
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-24591001
[Book] C型肝炎ウイルス(HCV)による感染-日本臨床ウイルス学会、臨床とウイルス2012
- Author(s)
  田中純子、小山富子、相崎英樹
- Data Source
  KAKENHI-PROJECT-21590867
[Book] 臨床とウイルス2012
- Author(s)
  田中純子、小山富子、相崎英樹.
- Publisher
  日本臨床ウイルス学会
- Data Source
  KAKENHI-PROJECT-24591001
[Book] 細胞2012
- Author(s)
  相崎英樹
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-24591001
[Book] 医学の歩み2012
- Author(s)
  相崎英樹
- Publisher
  医学の歩み社
- Data Source
  KAKENHI-PROJECT-24591001
[Book] Liver Forum in Kyoto第14回学術集会記録集2012
- Author(s)
  相崎英樹
- Publisher
  メディカルトリビューン
- Data Source
  KAKENHI-PROJECT-24591001
[Book] HCVの生活環における脂質の役割、日本臨床2011
- Author(s)
  相崎英樹
- Data Source
  KAKENHI-PROJECT-21590867
[Book] HCVの生活環における脂質の役割2011
- Author(s)
  相崎英樹
- Total Pages
  5
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-21590867
[Book] HCV感染における脂HCV感染における脂質代謝の変化とメタボロミクス解析、肝胆膵2011
- Author(s)
  相崎英樹、脇田隆字
- Data Source
  KAKENHI-PROJECT-21590867
[Book] C型肝炎ウイルスの複製と粒子形成2011
- Author(s)
  鈴木哲朗、原弘道、相崎英樹、鈴木亮介、政木隆博
- Total Pages
  6
- Publisher
  日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-21590867
[Book] 日本ウイルス学会、雑誌ウイルス2011
- Author(s)
  鈴木哲朗、原弘道, 相崎英樹、鈴木亮介、政木隆博
- Total Pages
  6
- Publisher
  C型肝炎ウイルスの複製と粒子形成
- Data Source
  KAKENHI-PROJECT-21590867
[Book] C型肝炎ウイルスの複製と粒子形成、日本ウイルス学会、雑誌ウイルス2011
- Author(s)
  鈴木哲朗、原弘道、相崎英樹、鈴木亮介、政木隆博
- Data Source
  KAKENHI-PROJECT-21590867
[Book] コレステロールとスフィンゴ脂質のC型肝炎ウイルス生活環における役割-ミノファーゲン製薬、Minophagen medical review2010
- Author(s)
  相崎英樹
- Data Source
  KAKENHI-PROJECT-21590867
[Book] 生体膜脂質のC型肝炎ウイルス生活環における役割、日本膜学会誌、膜2009
- Author(s)
  相崎英樹
- Data Source
  KAKENHI-PROJECT-21590867
[Book] 生体膜脂質のC型肝炎ウイルス生活環における役割2009
- Author(s)
  相崎英樹
- Total Pages
  6
- Publisher
  日本膜学会誌
- Data Source
  KAKENHI-PROJECT-21590867
[Book] C型肝炎に関する最近の情報2008
- Author(s)
  相崎英樹、鈴木哲朗、多田有希、岡部信彦、脇田隆字
- Publisher
  結核予防会機関誌「複十字」
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] Hepatocellular organellar abnormalities following elimination of hepatitis C virus2023
- Author(s)
  Aoyagi H, Iijima H, Gaber ES, Zaitsu T, Matsuda M, Wakae K, Watashi K, Suzuki R, Masaki T, Kahn J, Saito T, El-Kassas M, Shimada N, Kato K, Enomoto M, Hayashi K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Muramatsu M, Wake K, Wakita T, Aizaki H
- Journal Title
  
  Liver International
  
  Volume: 43 Issue: 8 Pages: 1677-1690
- DOI
  10.1111/liv.15624
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08342, KAKENHI-PROJECT-21K07974, KAKENHI-PROJECT-22K08587, KAKENHI-PROJECT-23K27415, KAKENHI-PROJECT-20H03499
[Journal Article] Induction of neutralizing antibodies against hepatitis C virus by a subviral particle-based DNA vaccine2022
- Author(s)
  Yato Keigo、Matsuda Mami、Watanabe Noriyuki、Watashi Koichi、Aizaki Hideki、Kato Takanobu、Tamura Koji、Wakita Takaji、Muramatsu Masamichi、Suzuki Ryosuke
- Journal Title
  
  Antiviral Research
  
  Volume: 199 Pages: 105266-105266
- DOI
  10.1016/j.antiviral.2022.105266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07974, KAKENHI-PROJECT-20H03499
[Journal Article] Independent evolution of multi-dominant viral genome species observed in a hepatitis C virus carrier2022
- Author(s)
  Ando Tomomi、Aizaki Hideki、Sugiyama Masaya、Date Tomoko、Hayashi Kazuhiko、Ishigami Masatoshi、Katano Yoshiaki、Goto Hidemi、Mizokami Masashi、Muramatsu Masamichi、Kuroda Makoto、Wakita Takaji
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 32 Pages: 101327-101327
- DOI
  10.1016/j.bbrep.2022.101327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07974, KAKENHI-PROJECT-20K08369
[Journal Article] Development and Use of a Kinetical and Real-Time Monitoring System to Analyze the Replication of Hepatitis C Virus2022
- Author(s)
  Xiaoyu Li, Masahiko Ito, Haruyo Aoyagi, Asako Murayama, Hideki Aizaki, Masayoshi Fukasawa, Takanobu Kato, Takaji Wakita, Tetsuro Suzuki
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Issue: 15 Pages: 8711-8711
- DOI
  10.3390/ijms23158711
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07051, KAKENHI-PROJECT-21K07974, KAKENHI-PROJECT-20K08369
[Journal Article] Patient-derived monoclonal antibody neutralizes HCV infection in vitro and vivo without generating escape mutants2022
- Author(s)
  Yokokawa Hiroshi、Shinohara Midori、Teraoka Yuji、Imamura Michio、Nakamura Noriko、Watanabe Noriyuki、Date Tomoko、Aizaki Hideki、Iwamura Tomokatsu、Narumi Hideki、Chayama Kazuaki、Wakita Takaji
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 9 Pages: e0274283-e0274283
- DOI
  10.1371/journal.pone.0274283
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07974, KAKENHI-PROJECT-20K08369
[Journal Article] Prolonged Gut Dysbiosis and Fecal Excretion of Hepatitis A Virus in Patients Infected with Human Immunodeficiency Virus.2021
- Author(s)
  Ishizaka A, Koga M, Mizutani T, Lim LA, Adachi E, Ikeuchi K, Ueda R, Aoyagi H, Tanaka S, Kiyono H, Matano T, Aizaki H, Yoshio S, Mita E, Muramatsu M, Kanto T, Tsutsumi T, Yotsuyanagi H
- Journal Title
  
  Viruses.
  
  Volume: 13 Issue: 10 Pages: 2101-2101
- DOI
  10.3390/v13102101
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07974
[Journal Article] Identification of natural compounds extracted from crude drugs as novel inhibitors of hepatitis C virus2021
- Author(s)
  Zheng Xin、Guo Rui、Liu Qingbo、Wakae Kousho、Watanabe Noriyuki、Fukano Kento、Que Lusheng、Li Yingfang、Aly Hussein H.、Watashi Koichi、Suzuki Ryosuke、Murayama Asako、Kato Takanobu、Aizaki Hideki、Wakita Takaji、Huang Xiaoxiao、Yan Yi、Song Shao-Jiang、Muramatsu Masamichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 567 Pages: 1-8
- DOI
  10.1016/j.bbrc.2021.06.022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07586, KAKENHI-PROJECT-19K23855, KAKENHI-PROJECT-20K08369, KAKENHI-PROJECT-21K07974, KAKENHI-PROJECT-20H03499
[Journal Article] Interferon-gamma induced APOBEC3B contributes to Merkel cell polyomavirus genome mutagenesis in Merkel cell carcinoma2021
- Author(s)
  Que L, Li Y, Dainichi T, Kukimoto I, Nishiyama T, Nakano Y, Shima K, Suzuki T, Sato Y, Horike S, Aizaki H, Watashi K, Kato T, Aly HH, Watanabe N, Kabashima K, Wakae K, Muramatsu M.
- Journal Title
  
  J Invest Dermatol
  
  Volume: S0022-202X(21) Issue: 7 Pages: 02636-1
- DOI
  10.1016/j.jid.2021.12.019
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11309, KAKENHI-PROJECT-19K07365, KAKENHI-PROJECT-19K07586, KAKENHI-PROJECT-20K09682, KAKENHI-PROJECT-21K07974, KAKENHI-PROJECT-21K08303, KAKENHI-PROJECT-22K16033
[Journal Article] NTCP Oligomerization Occurs Downstream of the NTCP-EGFR Interaction during Hepatitis B Virus Internalization2021
- Author(s)
  Fukano Kento、Oshima Mizuki、Tsukuda Senko、Aizaki Hideki、Ohki Mio、Park Sam-Yong、Wakita Takaji、Wakae Kousho、Watashi Koichi、Muramatsu Masamichi
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 24 Pages: 1-12
- DOI
  10.1128/jvi.00938-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07583, KAKENHI-PROJECT-19K23855, KAKENHI-PROJECT-21K07974, KAKENHI-PROJECT-20H03499
[Journal Article] Oncogenic transcriptomic profile is sustained in the liver after the eradication of the hepatitis C virus2021
- Author(s)
  Takeda Haruhiko、Takai Atsushi、Iguchi Eriko、Mishima Masako、Arasawa Soichi、Kumagai Ken、Eso Yuji、Shimizu Takahiro、Takahashi Ken、Ueda Yoshihide、Taura Kojiro、Hatano Etsuro、Iijima Hiroko、Aoyagi Haruyo、Aizaki Hideki、Marusawa Hiroyuki、Wakita Takaji、Seno Hiroshi
- Journal Title
  
  Carcinogenesis
  
  Volume: 42 Issue: 5 Pages: 672-684
- DOI
  10.1093/carcin/bgab014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08369, KAKENHI-PROJECT-21K07974
[Journal Article] Cellular OCIAD2 protein is a proviral factor for hepatitis C virus replication.2021
- Author(s)
  Yang Z, Ouyang T, Aoyagi H, Wang T, Xing X, Zhang Y, Wang Y, Li Y, Aizaki H, Li S, Kong L
- Journal Title
  
  Int J Biol Macromol.
  
  Volume: 188 Pages: 147-159
- DOI
  10.1016/j.ijbiomac.2021.08.032
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07974
[Journal Article] Development of an intervention system for linkage-to-care and follow-up for hepatitis B and C virus carriers2021
- Author(s)
  Kikuchi Minami、Sawabe Motoji、Aoyagi Haruyo、Wakae Kosho、Watashi Koichi、Hattori Satoru、Kawabe Naoto、Yoshioka Kentaro、Tanaka Junko、Muramatsu Masamichi、Wakita Takaji、Aizaki Hideki
- Journal Title
  
  Hepatology International
  
  Volume: 16 Issue: 1 Pages: 68-80
- DOI
  10.1007/s12072-021-10269-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08369, KAKENHI-PROJECT-21K07974, KAKENHI-PROJECT-20H03499
[Journal Article] Troglitazone Impedes the Oligomerization of Sodium Taurocholate Cotransporting Polypeptide and Entry of Hepatitis B Virus Into Hepatocytes2019
- Author(s)
  Fukano Kento、Tsukuda Senko、Oshima Mizuki、Suzuki Ryosuke、Aizaki Hideki、Ohki Mio、Park Sam-Yong、Muramatsu Masamichi、Wakita Takaji、Sureau Camille、Ogasawara Yuki、Watashi Koichi
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 9 Pages: 3257-3257
- DOI
  10.3389/fmicb.2018.03257
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-16K08383, KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-17H04085
[Journal Article] Regulation of Hepatitis C Virus Infection by Cellular Retinoic Acid Binding Proteins through the Modulation of Lipid Droplet Abundance2019
- Author(s)
  Bang Bo-Ram、Li Meng、Tsai Kuen-Nan、Aoyagi Haruyo、Lee Shin-Ae、Machida Keigo、Aizaki Hideki、Jung Jae U.、Ou Jing-Hsiung James、Saito Takeshi
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 8
- DOI
  10.1128/jvi.02302-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09034
[Journal Article] Activation of protein kinase R by hepatitis C virus RNA-dependent RNA polymerase.2019
- Author(s)
  Suzuki R, Matsuda M, Shimoike T, Watashi K, Aizaki H, Kato T, Suzuki T, Muramatsu M, Wakita T.
- Journal Title
  
  Virology
  
  Volume: 529 Pages: 226-233
- DOI
  10.1016/j.virol.2019.01.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02661, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-17H04085
[Journal Article] Epidermal growth factor receptor is a host entry cofactor triggering hepatitis B virus internalization2019
- Author(s)
  M. Iwamoto, W. Saso, R. Sugiyama, K. Ishii, M. Ohki, S. Nagamori, R. Suzuki, H. Aizaki, A. Ryo, J-H Yun, S-Y Park, N. Ohtani, M. Muramatsu, S. Iwami, Y. Tanaka, C. Sureau, T. Wakita and K. Watashi
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 116 Issue: 17 Pages: 8487-8492
- DOI
  10.1073/pnas.1811064116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05819, KAKENHI-PROJECT-16H04845, KAKENHI-PROJECT-18H01139, KAKENHI-PROJECT-16KT0111, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-15KT0107, KAKENHI-PROJECT-16K08825, KAKENHI-PROJECT-16K13777, KAKENHI-PROJECT-19K16672, KAKENHI-PROJECT-18H02413, KAKENHI-PROJECT-19J21455, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-16H04699
[Journal Article] Thermostable hepatitis C virus JFH1-derived variant isolated by adaptation to Huh7.5.1 cells2018
- Author(s)
  Shirasago Yoshitaka、Fukazawa Hidesuke、Aizaki Hideki、Suzuki Tetsuro、Suzuki Takeru、Sugiyama Kazuo、Wakita Takaji、Hanada Kentaro、Abe Ryo、Fukasawa Masayoshi
- Journal Title
  
  Journal of General Virology
  
  Volume: 99 Issue: 10 Pages: 1407-1417
- DOI
  10.1099/jgv.0.001117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09447, KAKENHI-PROJECT-17H04003, KAKENHI-PROJECT-18H02661, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-16K08260
[Journal Article] A Single Adaptive Mutation in Sodium Taurocholate Cotransporting Polypeptide Induced by Hepadnaviruses Determines Virus Species Specificity2018
- Author(s)
  Takeuchi Junko S.、Fukano Kento、Iwamoto Masashi、Tsukuda Senko、Suzuki Ryosuke、Aizaki Hideki、Muramatsu Masamichi、Wakita Takaji、Sureau Camille、Watashi Koichi
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 5 Pages: 04132-18
- DOI
  10.1128/jvi.01432-18
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-16J40232, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-17K15708
[Journal Article] The aryl hydrocarbon receptor?cytochrome P450 1A1 pathway controls lipid accumulation and enhances the permissiveness for hepatitis C virus assembly2018
- Author(s)
  Ohashi Hirofumi、Nishioka Kazane、Nakajima Syo、Kim Sulyi、Suzuki Ryosuke、Aizaki Hideki、Fukasawa Masayoshi、Kamisuki Shinji、Sugawara Fumio、Ohtani Naoko、Muramatsu Masamichi、Wakita Takaji、Watashi Koichi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Issue: 51 Pages: 19559-19571
- DOI
  10.1074/jbc.ra118.005033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09447, KAKENHI-PROJECT-18K05343, KAKENHI-PROJECT-18J14277, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-16H04699
[Journal Article] High-throughput neutralization assay for multiple flaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon.2018
- Author(s)
  Matsuda M, Yamanaka A, Yato K, Yoshii K, Watashi K, Aizaki H, Konishi E, Takasaki T, Kato T, Muramatsu M, Wakita T, Suzuki R
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 16624-16624
- DOI
  10.1038/s41598-018-34865-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03910, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-17H04085
[Journal Article] A new strategy to identify hepatitis B virus entry inhibitors by AlphaScreen technology targeting the envelope-receptor interaction.2018
- Author(s)
  Saso W, Tsukuda S, Ohashi H, Fukano K, Morishita R, Matsunaga S, Ohki M, Ryo A, Park SY, Suzuki R, Aizaki H, Muramatsu M, Sureau C, Wakita T, Matano T, Watashi K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 印刷中 Issue: 2 Pages: 374-379
- DOI
  10.1016/j.bbrc.2018.04.187
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-18J14277, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-17K15076, KAKENHI-PROJECT-17H04085
[Journal Article] Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide2018
- Author(s)
  Kaneko M, Futamura Y, Tsukuda S, Kondoh Y, Sekine T, Hirano H, Fukano K, Ohashi H, Saso W, Morishita R, Matsunaga S, Kawai F, Ryo A, Park S-Y, Suzuki R, Aizaki H, Ohtani N, Sureau C, Wakita T, Osada H, Watashi K
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 2769-2769
- DOI
  10.1038/s41598-018-20987-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05366, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-15K09034, KAKENHI-PROJECT-16K19145, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-17H04085, KAKENHI-PROJECT-16H04699
[Journal Article] Nonstructural 5A Protein of Hepatitis C Virus Interferes with Toll-Like Receptor Signaling and Suppresses the Interferon Response in Mouse Liver.2017
- Author(s)
  Tsutsumi T, Okushin K, Enooku K, Fujinaga H, Moriya K, Yotsuyanagi H, Aizaki H, Suzuki T, Matsuura Y, Koike K.
- Journal Title
  
  PLOS One
  
  Volume: 12 Issue: 1 Pages: 2017-2017
- DOI
  10.1371/journal.pone.0170461
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04735, KAKENHI-PROJECT-25293134, KAKENHI-PROJECT-15K09034
[Journal Article] Human Cathelicidin Compensates for the Role of Apolipoproteins in Hepatitis C Virus Infectious Particle Formation.2016
- Author(s)
  Puig-Basagoiti F, Fukuhara T, Tamura T, Ono C, Uemura K, Kawachi Y, Yamamoto S, Mori H, Kurihara T, Okamoto T, Aizaki H, Matsuura Y.
- Journal Title
  
  J Virol.
  
  Volume: 90(19) Pages: 8464-77
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09034
[Journal Article] Prolactin regulatory element binding protein is involved in hepatitis C virus replication compartment by interacting with NS4B.2016
- Author(s)
  Kong L, Fujimoto A, Nakamura M, Aoyagi H, Matsuda M, Watashi K, Suzuki R, Arita M, Yamagoe S, Dohmae N, Suzuki T, Sakamaki Y, Ichinose S, Suzuki T, Wakita T, Aizaki H.
- Journal Title
  
  J Virol.
  
  Volume: 90 Pages: 3093-111
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicits neutralizing antibodies against JEV and hepatitis C virus.2016
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Tajima S, Takasaki T, Konishi E, Kato T, Kohara M, Takeyama H, Wakita T, Suzuki R.
- Journal Title
  
  Sci Rep.
  
  Volume: 27 Pages: 28688-28688
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09034
[Journal Article] Prolactin regulatory element binding protein is involved in hepatitis C virus replication compartment by interacting with NS4B.2016
- Author(s)
  Kong L, Fujimoto A, Nakamura M, Aoyagi H, Matsuda M, Watashi K, Suzuki R, Arita M, Yamagoe S, Dohmae N, Suzuki T, Sakamaki Y, Ichinose S, Suzuki T, Wakita T, Aizaki H.
- Journal Title
  
  J Virol.
  
  Volume: 90(6) Pages: 3093-111
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09034
[Journal Article] Single-domain intrabodies against HCV Core inhibit viral propagation and Core-induced NF-κB Activation.2016
- Author(s)
  Suzuki R, Saito K, Matsuda M, Sato M, Kanegae Y, Shi G, Watashi K, Aizaki H, Chiba J, Saito I, Wakita T, Suzuki T.
- Journal Title
  
  J Gen Virol.
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Single-domain intrabodies against HCV Core inhibit viral propagation and Core-induced NF-κB Activation.2016
- Author(s)
  Suzuki R, Saito K, Matsuda M, Sato M, Kanegae Y, Shi G, Watashi K, Aizaki H, Chiba J, Saito I, Wakita T, Suzuki T.
- Journal Title
  
  J Gen Virol.
  
  Volume: 97(4) Pages: 887-92
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09034
[Journal Article] A Novel Tricyclic Polyketide, Vanitaracin A, Specifically Inhibits the Entry of Hepatitis B and D Viruses by Targeting Sodium Taurocholate Cotransporting Polypeptide.2015
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Ito T, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T.
- Journal Title
  
  J Virol.
  
  Volume: 89 Pages: 11945-53
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Journal Article] Dysregulation of Retinoic Acid Receptor Diminishes Hepatocyte Permissiveness to Hepatitis B Virus Infection through Modulation of NTCP Expression.2015
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Okada M, Sugiyama M, Kojima S, Tanaka Y, Mizokami M, Li J, Tong S, Wakita T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Pages: 5673-84
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] A Novel Tricyclic Polyketide, Vanitaracin A, Specifically Inhibits the Entry of Hepatitis B and D Viruses by Targeting Sodium Taurocholate Cotransporting Polypeptide.2015
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Ito T, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T.
- Journal Title
  
  J Virol.
  
  Volume: 89 Pages: 11945-53
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Dysregulation of Retinoic Acid Receptor Diminishes Hepatocyte Permissiveness to Hepatitis B Virus Infection through Modulation of NTCP Expression.2015
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Okada M, Sugiyama M, Kojima S, Tanaka Y, Mizokami M, Li J, Tong S, Wakita T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 27 Pages: 5673-84
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Journal Article] Targeting cellular squalene synthase, an enzyme essential for cholesterol biosynthesis, is a potential antiviral strategy against hepatitis C virus.2015
- Author(s)
  Saito K, Shirasago Y, Suzuki T, Aizaki H, Hanada K, Wakita T, Nishijima M, Fukasawa M. Targeting cellular squalene synthase, an enzyme essential for cholesterol biosynthesis, is a potential antiviral strategy against hepatitis C virus.
- Journal Title
  
  J Virol.
  
  Volume: 89 Pages: 2220-32
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09034
[Journal Article] Targeting cellular squalene synthase, an enzyme essential for cholesterol biosynthesis, is a potential antiviral strategy against hepatitis C virus.2015
- Author(s)
  Saito K, Shirasago Y, Suzuki T, Aizaki H, Hanada K, Wakita T, Nishijima M, Fukasawa M.
- Journal Title
  
  J Virol.
  
  Volume: 89 Pages: 2220-32
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Evaluation and Identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP2014
- Author(s)
  Iwamoto M, Watashi K, Tsukuda S, Aly1 HH, Fukasawa M, Suzuki R, Aizaki H, Ito T, Koiwai O, Kusuhara H, Wakita T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 443 Pages: 808-813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Involvement of MAP3K8 and miR-17-5p in poor virologic response to interferon-based combination therapy for chronic hepatitis C2014
- Author(s)
  Tsubota A, Mogushi K, Aizaki H, Miyaguchi K, Nagatsuma K, Matsudaira H, Kushida T, Furihata T, Tanaka H, Matsuura T.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 5 Pages: e97078-e97078
- DOI
  10.1371/journal.pone.0097078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-24591001, KAKENHI-PROJECT-26870175
[Journal Article] Production of single-round infectious chimeric flaviviruses with DNA-based Japanese encephalitis virus replicon2014
- Author(s)
  Suzuki R, Ishikawa T, Konishi E, Matsuda M, Watashi K, Aizaki H, Takasaki T, Wakita T
- Journal Title
  
  J Gen Virol
  
  Volume: 95 Issue: 1 Pages: 60-65
- DOI
  10.1099/vir.0.058008-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24102537, KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24590563, KAKENHI-PROJECT-24591001
[Journal Article] Alternative endocytosis pathway for productive entry of hepatitis C virus.2014
- Author(s)
  Matsuda M, Suzuki R, Kataoka C, Watashi K, Aizaki H, Kato N, Matsuura Y, Suzuki T, Wakita T
- Journal Title
  
  J Gen Virol.
  
  Volume: 95(Pt 12) Issue: 12 Pages: 2658-67
- DOI
  10.1099/vir.0.068528-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390111, KAKENHI-PROJECT-24591001, KAKENHI-PROJECT-25860832, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-26670224, KAKENHI-PROJECT-25293110, KAKENHI-PROJECT-25293134
[Journal Article] Nanoimaging of ssRNA: Genome Architecture of the Hepatitis C Virus Revealed by Atomic Force Microscopy.2014
- Author(s)
  Gilmore1 JL, Aizaki H, Yoshida1 A, Deguchi K, Kumeta M, Junghof J, Wakita T, Takeyasu K.
- Journal Title
  
  J Nanomed Nanotechol.
  
  Volume: doi:10.4172
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP2014
- Author(s)
  Iwamoto M, Watashi K, Tsukuda S, Aly HH, Fukasawa M, Fujimoto A, Suzuki R, Aizaki H, Ito T, Koiwai O, Kusuhara H, Wakita T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 443 Issue: 3 Pages: 808-813
- DOI
  10.1016/j.bbrc.2013.12.052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24102537, KAKENHI-PROJECT-24591001
[Journal Article] J Gen Virol.2014
- Author(s)
  Suzuki R, Ishikawa T, Konishi E, Matsuda M, Watashi K, Aizaki H, Takasaki T, Wakita T
- Journal Title
  
  Production of single-round infectious chimeric flaviviruses with DNA-based Japanese encephalitis virus replicon.
  
  Volume: 95 Pages: 60-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Development of hepatitis C virus genotype 3a cell culture system.2014
- Author(s)
  Kim S, Date T, Yokokawa H, Kono T, Aizaki H, Maurel P, Gondeau C, Wakita T.
- Journal Title
  
  Hepatology
  
  Volume: 60(6) Issue: 6 Pages: 1838-50
- DOI
  10.1002/hep.27197
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24591001
[Journal Article] Biochem Biophys Res Commun.2013
- Author(s)
  Nakajima S, Watashi K, Kamisuki S, Tsukuda S, Takemoto K, Matsuda M, Suzuki R, Aizaki H, Sugawara F, Wakita T
- Journal Title
  
  Specific inhibition of hepatitis C virus entry into host hepatocytes by fungi-derived sulochrin and its derivatives.
  
  Volume: 440 Pages: 515-520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] HCV NS3 protease enhancesliver fibrosis via binding to and activating TGF-β type I receptor2013
- Author(s)
  Sakata K, Eda S, Lee E, Hara M, Imoto M, Kojima S.
- Journal Title
  
  Scientific Reports
  
  Volume: 3 Issue: 1 Pages: 3243-3243
- DOI
  10.1038/srep03243
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23102006, KAKENHI-PROJECT-23390202, KAKENHI-PLANNED-24115003, KAKENHI-PROJECT-24390111, KAKENHI-PROJECT-25560419, KAKENHI-PROJECT-221S0001
[Journal Article] J Biol Chem.2013
- Author(s)
  Watashi K, Liang G, Iwamoto M, Marusawa H, Uchida N, Daito T, Kitamura K, Muramatsu M, Ohashi H, Kiyohara T, Suzuki R, Li J, Tong S, Tanaka Y, Murata K, Aizaki H, Wakita T.
- Journal Title
  
  Interleukin-1 and Tumor Necrosis Factor-α Trigger Restriction of Hepatitis B Virus Infection via a Cytidine Deaminase Activation-induced Cytidine Deaminase (AID).
  
  Volume: 288 Pages: 31715-31727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2.2013
- Author(s)
  Suzuki R, Matsuda M, Watashi K, Aizaki H, Matsuura Y, Wakita T, Suzuki T.
- Journal Title
  
  PLoS Pathog.
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Neutralizing antibodies induced by cell culture-derived hepatitis C virus protect against infection in mice.2013
- Author(s)
  Akazawa D, Moriyama M, Yokokawa H, Omi N, Watanabe N, Date T, Morikawa K, Aizaki H, Ishii K, Kato T, Mochizuki H, Nakamura N, Wakita T.
- Journal Title
  
  Gastroenterology.
  
  Volume: 145 Pages: 447-455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Antiviral activity of glycyrrhizin against hepatitis C virus in vitro.2013
- Author(s)
  Matsumoto Y, Matsuura T, Aoyagi H, Matsuda M, Hmwe SS, Date T, Watanabe N, Watashi K, Suzuki R, Ichinose S, Wake K, Suzuki T, Miyamura T, Wakita T, Aizaki H.
- Journal Title
  
  PLoS One.
  
  Volume: 18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor2013
- Author(s)
  Sakata K, Hara M, Terada T, Watanabe N, Takaya D, Yaguchi S, Matsumoto T, Matsuura T, Shirouzu M, Yokoyama S, Yamaguchi T, Miyazawa K, Aizaki H, Suzuki T, Wakita T, Imoto M, Kojima S
- Journal Title
  
  Sci Rep.
  
  Volume: 22 Pages: 7-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Trans-complemented hepatitis C virus particles as a versatile tool for study of virus assembly and infection.2012
- Author(s)
  Suzuki R, Saito K, Kato T, Shirakura M, Akazawa D, Ishii K, Aizaki H, Kanegae Y, Matsuura Y, Saito I, Wakita T, Suzuki T.
- Journal Title
  
  Virology.
  
  Volume: 10 Pages: 29-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Visualization and Measurement of ATP Levels in Living Cells Replicating Hepatitis C Virus Genome RNA.2012
- Author(s)
  Ando T, Imamura H, Suzuki R, Aizaki H, Watanabe T, Wakita T, Suzuki T.
- Journal Title
  
  PLOS Pathogen
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Visualization and measurement of ATP levels in living cells replieating hepatitis C virus genome RNA2012
- Author(s)
  Ando T, Imamura H, Suzuki R, Aizaki H, Watanabe T, Wakita T, Suzuki T
- Journal Title
  
  PLoS Pathog
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Visualization and Measurement of ATP Levels in Living Cells Replicating Hepatitis C Virus Genome RNA2012
- Author(s)
  Ando T, Imamura H, Suzuki R, Aizaki H, Watanabe T, Wakita T, Suzuki T
- Journal Title
  
  PLOS Pathogen
  
  Volume: 8
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Japanese reference panel of blood specimens for evaluation of hepatitis C virus RNA and core antigen quantitative assays.2012
- Author(s)
  Murayama A, Sugiyama N, Watashi K, Masaki T, Suzuki R, Aizaki H, Mizuochi T, Wakita T, Kato T.
- Journal Title
  
  J Clin Microbiol.
  
  Volume: 50 Pages: 1943-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] The Reference Panel of Japan for Evaluation of Hepatitis C Virus RNA and Core Antigen Quantitative Assays2012
- Author(s)
  Murayama A, Sugiyama N, Watashi K, Masaki T, Suzuki R, Aizaki H, Mizuochi T, Wakita T, Kato T
- Journal Title
  
  J Clin Microbiol.
  
  Volume: 11 Pages: 1943-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Hepatitis C virus translation preferentially depends on active RNA replication.2012
- Author(s)
  Liu HM, Aizaki H, Machida K, Ou JH, Lai MM.
- Journal Title
  
  PLoS One.
  
  Volume: ７
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591001
[Journal Article] Japanese reference panel of blood specimens for evaluation of hepatitis C virus RNA and core antigen quantitative assays2012
- Author(s)
  Murayama A, Sugiyama N, Watashi K, Masaki T, Suzuki R, Aizaki H, Mizuochi T, Wakita T, Kato T
- Journal Title
  
  J Clin Microbiol
  
  Volume: 50 Pages: 1943-9
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein2011
- Author(s)
  Inoue Y, Aizaki H, Hara H, Matsuda M, Ando T, Shimoji T, Murakami K, Masaki T, Shoji I, Homma S, Matsuura Y, Miyamura T, Wakita T, Suzuki T
- Journal Title
  
  Virology
  
  Volume: 410 Pages: 38-47
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Hepatitis C virus RNA replication in human stellate cells regulates gene expression of extracellular matrix-related molecules2011
- Author(s)
  Watanabe N, Aizaki H, Matsuura T, Kojima S, Wakita T, Suzuki T
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 407 Pages: 135-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Hepatitis C virus RNA replication in human stellate cells regulates gene expression of extracellular matrix-related molecules2011
- Author(s)
  Watanabe N, Aizaki H, Matsuura T, Kojima S, Wakita T, Suzuki T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 407 Pages: 135-40
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Hepatitis C virus RNA replication in human stellate cells regulates gene expression of extracellular matrix-related molecules2011
- Author(s)
  Watanabe, N., Aizaki, H., Matsuura, T., Kojima, S., Wakita, T., Suzuki, T
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 407(1) Issue: 1 Pages: 135-140
- DOI
  10.1016/j.bbrc.2011.02.125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390202
[Journal Article] Hepatitis C virus RNA replication in human stellate cells regulates gene expression of extracellular matrix-related molecules.2011
- Author(s)
  Watanabe N, Aizaki H, Matsuura T, Kojima S, Wakita T, Suzuki T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 407 Pages: 135-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein.2011
- Author(s)
  Inoue Y, Aizaki H, Hara H, Matsuda M, Ando T, Shimoji T, Murakami K, Masaki T, Shoji I, Homma S, Matsuura Y, Miyamura T, Wakita T, Suzuki T.
- Journal Title
  
  Virology.
  
  Volume: 410 Pages: 38-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Chaperonin TRiC/CCT participates in replication of hepatitis Cvirus genome via interaction with the viral NS5B protein2011
- Author(s)
  Inoue Y, Aizaki H, Hara H, Matsuda M, Ando T, Shimoji T, Murakami K, Masaki T, Shoji I, Homma S, Matsuura Y, Miyamura T, Wakita T, Suzuki T
- Journal Title
  
  Virology
  
  Volume: 410 Pages: 38-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] The structural requirements of virion-associated cholesterol for infectivity, buoyant density and apolipoprotein association of hepatitis C virus2011
- Author(s)
  Yamamoto M, Aizaki H, Fukasawa M, Teraoka T, Miyamura T, Wakita T, Suzuki T
- Journal Title
  
  J Gen.Virol.
  
  Volume: 92 Pages: 2082-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] The structural requirements of virion-associated cholesterol for infectivity, buoyant density and apolipoprotein association of hepatitis C virus2011
- Author(s)
  Yamamoto M, Aizaki H, Fukasawa M, Teraoka T, Miyamura T, Wakita T, Suzuki T
- Journal Title
  
  J Gen. Virol
  
  Volume: 92 Pages: 2082-1
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Identification of hepatitis C virus genotype 2a replicon variants with reduced susceptibility to ribavirin2010
- Author(s)
  Hmwe SS, Aizaki H, Date T, Murakami K, Ishii K, Miyamura T, Koike K, Wakita T, Suzuki T
- Journal Title
  
  Antiviral Res
  
  Volume: 85 Pages: 520-524
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Identification of hepatitis C virus genotype 2a replicon variants with reduced susceptibility to ribavirin.2010
- Author(s)
  Hmwe SS, Aizaki H, Date T, Murakami K, Ishii K, Miyamura T, Koike K, Wakita T, Suzuki T.
- Journal Title
  
  Antiviral Res.
  
  Volume: 85 Pages: 520-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Production of infectious hepatitis C virus by using RNA polymerase I-mediated transcription.2010
- Author(s)
  Masaki T, Suzuki R, Saeed M, Mori KI, Matsuda M, Aizaki H, Ishii K, Maki N, Miyamura T, Matsuura Y, Wakita T, Suzuki T.
- Journal Title
  
  J Virol.
  
  Volume: 84 Pages: 5824-5835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Production of infectious hepatitis C virus by using RNA polymerase I-mediated transcription2010
- Author(s)
  Masaki T, Suzuki R, Saeed M, Mori KI, Matsuda M, Aizaki H, Ishii K, Maki N, Miyamura T, Matsuura Y, Wakita T, Suzuki T
- Journal Title
  
  J Virol
  
  Volume: 84 Pages: 5824-5835
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Identification of hepatitis C virus genotype 2a replicon variants with reduced susceptibility to ribavirin2010
- Author(s)
  Hmwe SS, Aizaki H, Date T, Murakami K, Ishii K, Miyamura T, Koike K, Wakita T, Suzuki T
- Journal Title
  
  Antiviral Res. 85
  
  Pages: 520-524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] SYNCRIP (synaptotagmin-binding, cytoplasmic RNA-interacting protein) is a host factor involved in hepatitis C virus RNA replication2009
- Author(s)
  Liu HM, Aizaki H, Choi KS, Machida K, Ou JJ, Lai MM.
- Journal Title
  
  Virology 386
  
  Pages: 249-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] Evaluation of hepatitis C virus core antigen assays in detecting recombinant viral antigens of various genotypes2009
- Author(s)
  Saeed M, Suzuki R, Kondo M, Aizaki H, Kato T, Mizuochi T, Wakita T, Watanabe H, Suzuki T
- Journal Title
  
  J Clin Microbiol
  
  Volume: 47 Pages: 4141-4143
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Evaluation of Hepatitis C Virus Core Antigen Assays in Detecting the Recombinant Viral Antigens of Various Genotypes2009
- Author(s)
  Mohsan S, Suzuki R, Kondo M, Aizaki H, Kato T, Mizuochi T, Wakita T, Watanabe H, Suzuki T
- Journal Title
  
  J Clin Microbiol. 47
  
  Pages: 4141-4143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Involvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A protein2009
- Author(s)
  Hara H, Aizaki H, Matsuda M, Shinkai-Ouchi F, Inoue Y, Murakami K, Shoji I, Kawakami H, Matsuura Y, Lai MM, Miyamura T, Wakita T, Suzuki T.
- Journal Title
  
  J Virol. 84
  
  Pages: 5137-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] Proteomics analysis of mitochondrial proteins reveals over expression of a mitochondrial protein chaperone, prohibitin, in cells expressing hepatitis C virus core protein2009
- Author(s)
  Tsutsumi T, Matsuda M, Aizaki H, Moriya K, Miyoshi H, Fujie H, Shintani Y, Yotsuyanagi H, Miyamura T, Suzuki T, Koike K
- Journal Title
  
  Hepatology 50
  
  Pages: 378-386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] SYNCRIP(synaptotagmin-binding, cytoplasmic RNA-interacting protein)is a host factor involved in hepatitis C virus RNA replication2009
- Author(s)
  Liu HM, Aizaki H, Choi KS, Machida K, Ou JJ, Lai MM
- Journal Title
  
  Virology 386
  
  Pages: 249-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Involvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A protein2009
- Author(s)
  Hara H, Aizaki H, Matsuda M, Shinkai-Ouchi F, Inoue Y, Murakami K, Shoji I, Kawakami H, Matsuura Y, Lai MM, Miyamura T, Wakita T, Suzuki T
- Journal Title
  
  J Virol. 83
  
  Pages: 5137-5147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Proteomics analysis of mitochondrial proteins reveals overexpression of a mitochondrial protein chaperone, prohibitin, in cells expressing hepatitis C virus core protein2009
- Author(s)
  Tsutsumi T, Matsuda M, Aizaki H, Moriya K, Miyoshi H, Fujie H, Shintani Y, Yotsuyanagi H, Miyamura T, Suzuki T, Koike K
- Journal Title
  
  Hepatology
  
  Volume: 50 Pages: 378-386
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] SYNCRIP(synaptotagmin-binding, cytoplasmic RNA-interacting protein) is a host factor involved in hepatitis C virus RNA replication2009
- Author(s)
  Liu HM, Aizaki H, Choi KS, Machida K, Ou JJ, Lai MM
- Journal Title
  
  Virology
  
  Volume: 386 Pages: 249-256
- Data Source
  KAKENHI-PROJECT-21590867
[Journal Article] Dynamic behavior of hepatitis C virus quasispecies in a long-term culture of the three-dimensional radial-flow bioreactor system.2008
- Author(s)
  Murakami K, Inoue Y, Hmwe SS, Omata K, Hongo T, Ishii K, Yoshizaki S, Aizaki H, Matsuura T, Shoji I, Miyamura T, Suzuki T
- Journal Title
  
  J Virol Methods 148
  
  Pages: 174-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] A Critical Role of Virion-Associated Cholesterol and Sphingolipid in Hepatitis C Virus Infection2008
- Author(s)
  Aizaki H, Morikawa K, Fukasawa M, Hara H, Inoue Y, Tani H, Saito K, Nishijima M, Hanada K, Matsuura Y, Lai MM, Miyamura T, Wakita T, Suzuki T.
- Journal Title
  
  J Virol. 82
  
  Pages: 5715-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] Dynamic behavior of hepatitis C virus quasispecies in a long-term culture of the three-dimensional radial-flow bioreactor system2008
- Author(s)
  Murakami K, Inoue Y, Hmwe SS, Omata K, Hongo T, Ishii K, Yoshizaki S, Aizaki H, Matsuura T, Shoji I, Miyamura T. Suzuki T
- Journal Title
  
  J Virol Methods 148
  
  Pages: 174-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] A Critical Role of Vrion-Associated Cholesterol and Sphingolipid in Hepatitis C Virus Infection2008
- Author(s)
  Aizaki H, 他
- Journal Title
  
  J Virol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041074
[Journal Article]2008
- Author(s)
  鈴木哲朗, 政木隆博, 相崎英樹
- Journal Title
  
  ウイルス(日本ウイルス学会)
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles2008
- Author(s)
  Masaki T, Suzuki R, Murakami K, Aizaki H, Ishii K, Murayama A, Date T, Matsuura Y, Miyamura T, Wakita T, Suzuki T.
- Journal Title
  
  J Virol. 82
  
  Pages: 7964-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] Critical role of virion -associated cholesterol and sphingolipid in hepatitis C virus infection.2008
- Author(s)
  Aizaki H, M, 他7名Hanada K, Matsuura Y, Lai MM, Miyamura T, Wakita T, Suzuki T.
- Journal Title
  
  J Virol 82(12)
  
  Pages: 5715-24
- Data Source
  KAKENHI-PROJECT-19041074
[Journal Article] ヒト肝癌細胞の三次元培養化に伴う遺伝子発現変動の網羅的解析2008
- Author(s)
  葛岡健太郎, 岩田耕一郎, 吉崎佐矢香, 相崎英樹, 鈴木哲朗, 長尾垣
- Journal Title
  
  東京医大誌 66
  
  Pages: 212-223
- NAID
  10024169293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] A Critical Role of Virion-Associated Cholesterol and Sphingolipid in Hepatitis C Virus Infection2008
- Author(s)
  Aizaki H, Morikawa K, Fukasawa M, Hara H, Inoue Y, Tani H, Saito K, Nishijima M, Hanada K, Matsuura Y, Lai MM, Miyamura T, Wakita T, Suzuki T.
- Journal Title
  
  J Virol. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article]2008
- Author(s)
  Aizaki H, Suzuki T.
- Journal Title
  
  Structure-based Study of Viral Replication(World Scientific)
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] Hepatitis C viral life cycle.2007
- Author(s)
  Suzuki T, Ishii K, Aizaki H, Wakita T
- Journal Title
  
  Adv Drug Deliv Rev 59
  
  Pages: 1200-1212
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] Transcriptomic comparison of human hepatoma Huh-7 cell clones with different hepatitis C virus replication efficiencies.2007
- Author(s)
  Inoue Y, Murakami K, Hmwe SS, Aizaki H, Suzuki T.
- Journal Title
  
  Jpn J Infect Dis. 60
  
  Pages: 173-178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] Molecular biology of hepatitis C virus.2007
- Author(s)
  Suzuki T., Aizaki H, Murakami K, Shoji I, Wakita T
- Journal Title
  
  J Gastroenterol 42
  
  Pages: 411-423
- NAID
  40016676275
- Data Source
  KAKENHI-PROJECT-19590799
[Journal Article] HCV増殖機構の解明2006
- Author(s)
  相崎英樹.他
- Journal Title
  
  別冊・医学のあゆみ・消化器疾患Ver.3 II. 肝・胆・膵
  
  Pages: 143-6
- Data Source
  KAKENHI-PROJECT-18390225
[Journal Article] Production of infectious hepatitis C virus by using RNA polymerase I-mediated transcription
- Author(s)
  Masaki T, Suzuki R, Saeed M, Mori KI, Matsuda M, Aizaki H, Ishii K, Maki N, Miyamura T, Matsuura Y, Wakita T, Suzuki T
- Journal Title
  
  J Virol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] C型肝炎ウイルス除去後のオルガネラ異常.2023
- Author(s)
  青柳東代、飯島尋子、松田麻未、若江亨祥、渡士幸一、鈴木亮介、政木隆博、杉山真也、坪田昭人、島田紀朋、加藤慶三、林和彦、榎本大、三又絢子、酒巻有里子、市野瀬志津子、村松正道、溝上雅史、和氣健二郎、脇田隆字、相崎英樹.
- Organizer
  第６９回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] Hepatocellular organelle and gene expression abnormalities following.2023
- Author(s)
  Aoyagi H, Iijima H, Kikuchi M, Gewaid HE, Matsuda M, Watashi K, Suzuki R, Masaki T, Shimada N, Kato K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Muramatsu M, Wake K, Sugiyama M, Mizokami M, Wakita T, Aizaki H.
- Organizer
  29th International Symposium on Hepatitis C Virus and Related Viruses. Atlanta.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] Hepatocellular organelle and gene expression abnormalities following elimination of hepatitis C virus and carcinogenesis.2023
- Author(s)
  Haruyo Aoyagi, Hiroko Iijima, Koichi Watashi, Ryosuke Suzuk, Takahiro Masaki, Noritomo Shimada, Keizo Kato, Akihito Tsubota, Yuriko Sakamaki, Shizuko Ichinose, Kenjiro Wake, Masaya Sugiyama, Masashi Mizokami, Takaji Wakita, Hideki Aizaki.
- Organizer
  第3回 International Liver Conference 2023. 東京
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] RHV RNA複製の高いcured細胞の樹立とその評価2023
- Author(s)
  園部円、渡邉則幸、鈴木貴也、小柳円、有村裕、相崎英樹、村松正道、脇田隆字
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] ラット肝炎ウイルス感染動物モデルを用いたC型肝炎ウイルスワクチン開発2023
- Author(s)
  渡邉則幸、園部円、鈴木貴也、李天成、須崎百合子、網康至、花木賢一、小柳円、有村裕、鈴木亮介、相崎英樹、村松正道、脇田隆字
- Organizer
  第26回日本ワクチン学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] RHV RNA複製の高いcured細胞の樹立とその評価2022
- Author(s)
  園部円、渡邉則幸、鈴木貴也、小柳円、有村裕、相崎英樹、村松正道、脇田隆字
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] Hepatocellular organellar abnormalities following elimination of hepatitis C virus2022
- Author(s)
  Haruyo Aoyagi, Hiroko Iijima, Minami Kikuchi, Mami Matsuda, Koichi Watashi, Ryosuke Suzuki, Takahiro Masaki, Noritomo Shimada, Keizo Kato, Akihito Tsubota, Ayako Mimata, Yuriko Sakamaki, Shizuko Ichinose, Masamichi Muramatsu, Kenjiro Wake, Masaya Sugiyama, Masashi Mizokami, Takaji Wakita, Hideki Aizaki.
- Organizer
  28th International Symposium on Hepatitis C Virus, Flaviviruses, and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] ラット肝炎ウイルス感染動物モデルを用いたC型肝炎ウイルスワクチン開発2022
- Author(s)
  渡邉則幸、園部円、鈴木貴也、李天成、須崎百合子、網康至、花木賢一、小柳円、有村裕、鈴木亮介、相崎英樹、村松正道、脇田隆字
- Organizer
  第26回日本ワクチン学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] C型肝炎ウイルス除去後のオルガネラ異常2022
- Author(s)
  青柳東代、飯島尋子、松田麻未、若江亨祥、渡士幸一、鈴木亮介、政木隆博、杉山真也、坪田昭人、島田紀朋、加藤慶三、林和彦、榎本大、三又絢子、酒巻有里子、市野瀬志津子、村松正道、溝上雅史、和氣健二郎、脇田隆字、相崎英樹
- Organizer
  第６９回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] HIV陽性者におけるA型肝炎ウイルス罹患による急性炎症と腸内細菌叢の動態解析2021
- Author(s)
  石坂彩、古賀道子、水谷壮利、林阿英、安達英輔、池内和彦、上田竜大、青柳東代、清野宏、俣野哲朗、相崎英樹、由雄祥代、村松正道、考藤達哉、堤武也、四柳宏
- Organizer
  第35回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] Development of a community-based intervention system for linkage to care and follow-up for hepatitis virus-positive individuals cooperating with health care providers2021
- Author(s)
  Minami Kikuchi, Haruyo Aoyagi, Kosho Wakae, Koichi Watashi, Satoru Hattori, Naoto Kawabe, Kentaro Yoshioka, Junko Tanaka, Masamichi Muramatsu, Takaji Wakita, Motoji Sawabe, Hideki Aizaki
- Organizer
  Global Heapatitis Summit, The 17th International Symposium on Viral Hepatitis and Liver Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] 感染受容体NTCPの多量体化が導くB型肝炎ウイルス内在化機構の解明2021
- Author(s)
  深野顕人, 大嶋美月, 九十田千子, 相崎英樹, 大木規央, 朴三用, 脇田隆字, 若江亨祥, 渡士幸一, 村松正道
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] Abnormal hepatocellular organelles in patients with sustained virological response2021
- Author(s)
  Haruyo Aoyagi, Hiroko Iijima Minami Kikuchi, Mami Matsuda, Koichi Watashi, Ryosuke Suzuki, Takahiro Masaki, Noritomo Shimada, Keizo Kato, Akihito Tsubota, Takeya Tsutsumi, Kazuya Okushin, Kyoji Moriya, Kazuhiko Koike, Masamichi Muramatsu, Kenjiro Wake, Takaji Wakita, Hideki Aizaki
- Organizer
  The 21th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] 新規の作用によりB型肝炎ウイルス感染を阻害する酸化ステロール合成誘導体の同定2021
- Author(s)
  大嶋美月, 深野顕人, 岩本将士, Frank Stappenbeck, Feng Wang, 鄭シン, 山崎雅子, 若江亨祥, 相崎英樹, 倉持幸司, 村松正道, 脇田隆字, Farhad Parhami, 渡士幸一
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] SLC10A1/NTCP多量体形成が制御するB型肝炎ウイルス細胞内侵入機構の解析2021
- Author(s)
  深野顕人, 大嶋美月, 九十田千子, 相崎英樹, 大木規央, 朴三用, 脇田隆字, 若江亨祥, 渡士幸一, 村松正道
- Organizer
  第94回日本生化学大会
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] Identification of an oxysterol derivative that inhibits HBV infection by interrupting NTCP oligomerization2021
- Author(s)
  Oshima M, Fukano K, Iwamoto M, Stappenbeck F, Wang F, Wakae K, Aizaki H, Kuramochi K, Muramatsu M, Wakita T, Parhami F, Watashi K
- Organizer
  第68回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] NTCP oligomerization is initiated downstream of the NTCP-EGFR interaction during HBV internalization2021
- Author(s)
  Kento Fukano, Mizuki Oshima, Senko Tsukuda, Hideki Aizaki, Mio Ohki, Sam-Yong Park, Takaji Wakita, Kousho Wakae, Koichi Watashi, Masamichi Muramatsu
- Organizer
  International HBV meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] 自治体と医療関係者が連携した肝炎ウイルスキャリアの動向調査および陽性者のフォローアップシステムによる行動変容の解析2021
- Author(s)
  菊池みなみ, 川部直人, 青柳東代, 服部悟, 若江亨祥, 渡士幸一, 吉岡健太郎, 佐竹正博, 是永匡昭, 田中純子, 村松正道, 脇田隆字, 沢辺元司, 相崎英樹
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-21K07974
[Presentation] Identification of Alyl hydrocarbon receptor ligands inhibiting the lipid accumulation and hepatitis C virus production.2018
- Author(s)
  Kazane Nishioka, Hirofumi Ohashi, Ryosuke Suzuki, Hideki Aizaki, Masamichi Muramatsu, Takaji Wakita, Koichi Watashi.
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Identification of Alyl hydrocarbon receptor ligands inhibiting the lipid accumulation and hepatitis C virus production.2018
- Author(s)
  Kazane Nishioka, Hirofumi Ohashi, Ryosuke Suzuki, Hideki Aizaki, Masamichi Muramatsu, Takaji Wakita, Koichi Watashi.
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Construction of chimeric reporter HCV efficient production capacity.2018
- Author(s)
  Rika Sato, Noriyuki Watanabe, Hussein Aly, Madoka Koyanagi, Yutaka Arimura, Hideki Aizaki, Masamichi Muramatsu, Takaji Wakita.
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Alyl hydrocarbon receptor-cytochrome p450 1a1 pathway regulates hepatic lipid biosynthesis to maximize Hepatitis C virus production.2018
- Author(s)
  Hirofumi Ohashi, Syo Nakajima, Sulyl Kim, Ryosuke Suzuki, Hideki Aizaki, Masayoshi Fukasawa, Shinji Kamisuki, Fumio Sugawara, Naoko Ohtani, Masamichi Muramatsu, Takaji Wakita, Koichi Watashi.
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Flavivirus subviral particles-based DNA vaccine induces neutralizing antibodies against HCV.2018
- Author(s)
  Keigo Yato, Mami Matsuda, Noriyuki Watanabe, Shogo Nakajima, Akira Fujimoto, Koichi Watashi, Hideki Aizaki, Takanobu Kato, Koji Tamura, Masamichi Muramatsu, Takaji Wakita, Ryosuke Suzuki.
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] HCVに対する抗ウイルス治療後、SVR後の肝細胞の超微細構造の変化.2018
- Author(s)
  青柳東代, 飯島尋子, 松田麻未, 渡士幸一, 鈴木亮介, 政木隆博, 酒巻有里子, 市野瀬志津子, 坪田昭人, 和氣健二郎, 脇田隆字, 相崎英樹.
- Organizer
  第２６回抗ウイルス療法学会総会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Hepatitis C virus infection triggers the transavtivation of alyl hydrocarbon receptor to rearrange hepatic lipid biosynthesis.2018
- Author(s)
  Hirofumi Ohashi, Syo Nakajima, Sulyl Kim, Ryosuke Suzuki, Hideki Aizaki, Masayoshi Fukasawa, Shinji Kamisuki, Fumio Sugawara, Naoko Ohtani, Masamichi Muramatsu, Takaji Wakita, Koichi Watashi.
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] HCV genome and abnormal organelles in the liver after elimination of hepatitis C virus by drug treatment.2018
- Author(s)
  Hideki Aizaki, Haruyo Aoyagi, Hiroko Iijima, Xin Zheng, Mami Matsuda, Koichi Watashi, Ryosuke Suzuki, Takahiro Masaki, Noritomo Shimada, Keizo Kato, Akihito Tsubota, Takeshi Saito, Kazuhiko Hayashi, Masaru Enomoto, Ayako Mimata, Yuriko Sakamaki, Shizuko Ichinose, Kenjiro Wake, Masamichi Muramatsu, Takaji Wakita.
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Development and use of chronological and real-time monitoring system of hepatitis C virus RNA replication.2018
- Author(s)
  Xiaoyu Li, Masahiko Ito, Kenji Nakashima, Haruyo Aoyagi, Hideki Aizaki, Tetsuro Suzuki.
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Construction of chimeric reporter HCV with efficient production capacity.2018
- Author(s)
  Rika Sato, Noriyuki Watanabe, Hussein Aly, Madoka Koyanagi, Yutaka Arimura, Hideki Aizaki, Masamichi Muramatsu, Takaji Wakita.
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Epidemiology Study of Acute Hepatitis B and C in Japan, from April 19992018
- Author(s)
  Xin Zheng, Haruyo Aoyagi, Gewaid E. Hossam, Takuma Zaitsu, Francesc Puig-Basagoiti, Yu Ting Kao, Koichi Watashi, Ryosuke Suzuki, Takuri Takahashi, Tomimasa Sunagawa, Kazunori Oishi, Takaji Wakita, Hideki Aizaki.
- Organizer
  6th JAPAN-TAIWAN-KOREA HBV Research Symposium 2018
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Establishment of infectious genotype 4a HCVcc.2018
- Author(s)
  Noriyuki Watanabe, Takaya Suzuki, Tomoko Date, Su Su Hmwe, Hussein Aly, Masaya Sugiyama, Masashi Mizokami, Hideki Aizaki, Masamichi Muramatsu, Takaji Wakita.
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Abnormal hepatocellular organelles remain to be observed in sustained virological response (SVR) patients.2018
- Author(s)
  Haruyo Aoyagi, Hiroko Iijima, Xin Zheng, Yu Ting Kao, Mami Matsuda, Koichi Watashi, Ryosuke Suzuki, Takahiro Masaki, Noritomo Shimada, Keizo Kato, Akihito Tsubota, Kenjiro Wake, Takaji Wakita, Hideki Aizaki.
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Antiviral activity of phospholipase A2 group V (PLA2G5) against HCV.2018
- Author(s)
  Francesc Puig-Basagoiti, Masayoshi Fukasawa, Ryosuke Suzuki, Koichi Watashi, Masamichi Muramatsu, Takaji Wakita, Hideki Aizaki.
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Establishment of infectious genotype 4a HCVcc.2018
- Author(s)
  Noriyuki Watanabe, Takaya Suzuki, Tomoko Date, Su Su Hmwe, Hussein Aly, Hideki Aizaki, Masaya, Sugiyama, Masashi Mizokami, Mohamed El Kassas, Ashraf Tabll, William Delaney, Guofeng Cheng, Masamichi Muramatsu, Takaji Wakita.
- Organizer
  25th International Symposium on Hepatitis C Virus and Related Viruses.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Structural proteins of hepatitis C virus Genotype 3a S310 strain permit claudin-1-independent entry.2017
- Author(s)
  Suzuki R, Yato K, Tosaka T, Su Su Hmwe, Matsuda M, Watashi K, Aizaki H, Fukasawa M, Matsuura Y, Wakita T
- Organizer
  24th International Symposium on Hepatitis C Virus and Related Viruses.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Sphingomyelin participates in the formation of Hepatitis C virus membrane replication vesicles.2017
- Author(s)
  Gewaid HE, Aoyagi H, Kao YU, Zheng X, Puig-Basagoiti F, Watashi K, Arita M, Suzuki R, Aly HH, Kumagai K, Yamaji T, Fukasawa M, Mimata A, Sakamaki Y, Ichinose S, Hanada K, Wakita T, Aizaki H
- Organizer
  24th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Novel crosstalk of Xenobiotic Response with Lipid Biosynthesis Pathway regulates the Host Permissiveness to the Hepatitis C Virus Production2017
- Author(s)
  Ohashi H, Nakajima S, Kim S, Fukasawa M, Suzuki R, Aizaki H, Sugawara F, Ohtani N, Wakita T, Watashi K
- Organizer
  日本ウイルス学会第65回学術集会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Membrane protein, embryonic lethal, abnormal vision, drosophila-like 1, interacts with NS5A and involves in hepatitis C virus replication2017
- Author(s)
  Kao YT, Goto K, Aoyagi H, Hossam GE, Zheng X, Puig-Basagoiti F, Watashi K, Suzuki R, Yamagoe S, Dohmae N, Suzuki T, Okushin K, Tsutsumi T, Yotsuyanagi H, Moriya K, Koike K, Suzuki T, Wakita T, Aizaki H
- Organizer
  日本ウイルス学会第65回学術集会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Sphingomyelin participates in the formation of Hepatitis C virus membrane replication vesicles2017
- Author(s)
  Gewaid HE, Aoyagi H, Arita M, Watashi K, Suzuki R, Aly HH, Kumagai K, Yamaji T, Fukasawa M, Mimata A, Sakamaki Y, Ichinose S, Hanada K, Wakita T, Aizaki H
- Organizer
  American Society for Virology - 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Generation of hepatitis C virus vaccine antigen based on Japanese encephalitis virus subviral particles.2017
- Author(s)
  Yato K, Matsuda M, Watanabe N, Nakajima S, Fujimoto A, Watashi K, Aizaki H, Kato T, Tamura K, Wakita T, Suzuki R.
- Organizer
  日本ウイルス学会第65回学術集会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] NS5A-Associated Membrane Protein, Embryonic Lethal, Abnormal Vision, Drosophila-Like 1, Involves in Hepatitis C Replication2017
- Author(s)
  Kao YT, Goto K, Aoyagi H, Hossam GE, Zheng X, Puig-Basagoiti F, Watashi K, Suzuki R, Yamagoe S, Dohmae N, Suzuki T, Okushin K, Tsutsumi T, Yotsuyanagi H, Moriya K, Koike K, Suzuki T, Wakita T, Aizaki H
- Organizer
  24th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] C型慢性肝炎のウイルス学的著効（SVR）後の肝実質細胞のオルガネラ異常の解析2017
- Author(s)
  青柳東代, 飯島尋子, Francesc Puig-Basagoiti, Zheng Xin, Yu Ting Kao, Gewaid E. Hossam, 在津拓馬, 松田麻未, 渡士幸一, 鈴木亮介, 政木隆博, 島田紀明, 加藤慶三, 坪田昭人, 三又絢子, 酒巻有里子, 市野瀬志津子, 和氣健二郎, 脇田隆字, 相崎英樹
- Organizer
  第27回抗ウイルス療法学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Abnormal organelles were continuously observed in sustained virological response (SVR) patients2017
- Author(s)
  Aoyagi H, Iijima H, Puig-Basagoiti F, Zheng X, Kao YT, Gewaid HE, Zaitsu T, Matsuda M, Watashi K, Suzuki R, Masaki T, Shimada N, Kato K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Wake K, Wakita T, Aizaki H
- Organizer
  The Asian Pacific Associaton for the Study of the Liver - Single Topic Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Ultrastructure of hepatocytes in chronic hepatitis C patients who achieve a sustained virological response.2017
- Author(s)
  Aoyagi H, Iijima H, Puig-Basagoiti F, Zheng X, Kao YT, Hossam GE, Zaitsu T, Matsuda M, Watashi K, Suzuki S, Masaki T, Shimada N, Kato K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Wake K, Wakita T, Aizaki H.
- Organizer
  The Asian Pacific Association for the Study of the Liver
- Place of Presentation
  China
- Year and Date
  2017-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Human hepatic stellate cells are permissive for hepatitis C virus infection/replication and play important roles in fibrosis2017
- Author(s)
  Zheng X, Zaitsu T, Aoyagi H, Matsuda M, Watanabe N, Fujimoto A, Watashi K, Suzuki R, Fukuhara T, Matsuura Y, Ichinose S, Wake K, Suzuki T, Iijima H, Yokoyama H, Masaki T, Matsuura T, Tamura K, Wakita T, Aizaki H
- Organizer
  日本ウイルス学会第65回学術集会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Phosphorylation of protein kinase R and translational suppression by NS5B protein of hepatitis C virus.2017
- Author(s)
  Suzuki R, Matsuda M, Shimoike T, Watashi k, Aizaki H, Kato T, Suzuki T, Wakita T.
- Organizer
  日本ウイルス学会第65回学術集会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Acute hepatitis C virus infection among HIV-infected men who have sex with men2017
- Author(s)
  Aoyagi H, Itoda I, Zheng X, Hossam GE, Puig-Basagoiti F, Kao YT, Watashi K, Suzuki R, Wakita T, Aizaki H
- Organizer
  APASL Single Topic Conference 2017 Mongolia 6th HCV Conference on HCV and CO-INFECTIONS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Abnormal hepatocellular organelles remain to be observed in sustained virological response patients2017
- Author(s)
  Aoyagi H, Iijima H, Puig-Basagoiti F, Zheng X, Kao YT, Hossam GE, Matsuda M, Watashi K, Suzuki R, Masaki T, Aizawa N, Shimada N, Kato K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Wake K, Wakita T, Aizaki H
- Organizer
  日本ウイルス学会第65回学術集会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Novel Crosstalk of Xenobiotic Response with Lipid Metabolism Regulates the Host Permissivenessto Hepatitis C Virus Production2017
- Author(s)
  Ohashi H, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Wakita T, Watashi K
- Organizer
  24th International Symposium on Hepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Crosstalk of Xenobiotic Metabolism Pathway with Lipid Metabolism regulates the Host Permissiveness to Hepatitis C Virus Production2017
- Author(s)
  Ohashi H, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Wakita T, Watashi K
- Organizer
  第14回ウイルス学キャンプin湯河原
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] HCVの肝星細胞への感染および肝星細胞活性化のメカニズム解析2017
- Author(s)
  相崎英樹、渡士幸一、鈴木哲朗、政木隆博、横山寛、脇田隆字
- Organizer
  第53回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Activation of protein kinase R by hepatitis C virus RNA-dependent RNA polymerase.2016
- Author(s)
  Suzuki R, Matsuda M, Shimoike T, Watashi K, Aizaki H, Kato T, Suzuki T, Wakita T.
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Japan
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Prolactin regulatory element binding protein and Surfeit 4 are involved in hepatitis C virus replication compartment by interacting with NS4B.2016
- Author(s)
  Kong L, Fujimoto A, Nakamura M, Aoyagi H, Matsuda M, Watashi K, Suzuki R, Arita M, Yamagoe S, Dohmae N, Suzuki T, Sakamaki Y, Ichinose S, Suzuki T, Wakita T, Aizaki H.
- Organizer
  Asian Pacific Association for the Study of the Liver
- Place of Presentation
  東京
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Sphingomyelin is a component in the membranous replication factories.2016
- Author(s)
  Gewaid HE, Aoyagi H, Watashi K, Suzuki R, Aly H, Kumagai K, Yamaji T, Fukasawa M, Mimata A, Sakamaki Y, Ichinose S, Hanada K, Wakita T, Aizaki H.
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Japan
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Human hepatic stellate cells are permissive for hepatitis C virus infection/replication and play important roles in fibrosis.2016
- Author(s)
  Zaitsu T, Aoyagi H, Matsuda M, Watanabe N, Fujimoto A, Watashi K, Suzuki R, Fukuhara T, Matsuura Y, Wake K, Suzuki T, Matsuura T, Tamura K, Wakita T, Aizaki H.
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses. Kyoto
- Place of Presentation
  Japan
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Prolactin regulatory element binding protein and Surfeit 4 are involved in hepatitis C virus replication compartment by interacting with NS4B.2016
- Author(s)
  Kong L, Fujimoto A, Nakamura M, Aoyagi H, Matsuda M, Watashi K, Suzuki R, Arita M, Yamagoe S, Dohmae N, Suzuki T, Sakamaki Y, Ichinose S, Suzuki T, Wakita T, Aizaki H.
- Organizer
  Asian Pacific Association for the Study of the Liver
- Place of Presentation
  東京
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] スフィンゴ脂質のC型肝炎ウイルス複製における役割の解析.2016
- Author(s)
  ホッサムゲワイド、口頭、青柳東代、渡士幸一、鈴木亮介、熊谷圭悟、山地俊之、深澤征義、酒巻有里子、市野瀬志津子、花田賢太郎、脇田隆字、相崎英樹.
- Organizer
  第５８回日本脂質生化学学会
- Place of Presentation
  秋田
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Surfeit 4 is involved in HCV replication by interacting with NS4B. Positive-strand RNA viruses2016
- Author(s)
  Kong L, Aoyagi H, Matsuda M, Fujimoto A, Watashi K, Suzuki R, Suzuki T, Wakita T, Aizaki1 H,
- Organizer
  Plus strand RNA meeting
- Place of Presentation
  USA
- Year and Date
  2016-05-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Role of lipid droplets in the emergence of drug resistant virus against direct acting antivirals.2016
- Author(s)
  Ohashi H, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Wakita T, Watashi K.
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Japan
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Ultrastructure of hepatocytes in chronic hepatitis C patients who achieve a sustained virological response.2016
- Author(s)
  Aoyagi H, Iijima H, Puig-Basagoiti F, Zheng X, Kao YT,. Hossam GE, Zaitsu T, Matsuda M, Watashi K, Suzuki R, Masaki T, Shimada N, Kato K, Tsubota A, Mimata A, Sakamaki Y, Ichinose S, Wake K, Wakita T, Aizaki H.
- Organizer
  The 15th Awaji International Forum on Infection and Immunity.
- Place of Presentation
  Japan
- Year and Date
  2016-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] HCVに対する抗ウイルス治療後、SVR後の肝細胞の超微細構造の変化2016
- Author(s)
  青柳東代、飯島尋子、松田麻未、渡士幸一、鈴木亮介、會澤信弘、政木隆博、坪田昭人、和氣健二郎、脇田隆字、相崎英樹
- Organizer
  第41回日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Aryl hydrocarbon receptor regulates the assembly of hepatitis C virus and affects the emergence of drug resistant virus against DAAs.2016
- Author(s)
  Ohashi H, Nakajima S, Kim S, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Wakita T, Watashi K.
- Organizer
  日本ウイルス学会第64回学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] HCVに対する抗ウイルス治療後、SVR後の肝細胞の超微細構造の変化2016
- Author(s)
  青柳東代、飯島尋子、松田麻未、渡士幸一、鈴木亮介、政木隆博、三又絢子、酒巻有里子、市野瀬志津子、坪田昭人、和氣健二郎、脇田隆字、相崎英樹
- Organizer
  広島肝臓プロジェクト研究センターシンポジウム
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] HCVに対する抗ウイルス治療後、SVR後の肝細胞の超微細構造の変化.2016
- Author(s)
  青柳東代、飯島尋子、松田麻未、渡士幸一、鈴木亮介、政木隆博、坂巻有里子、市野瀬志津子、坪田昭人、和氣健二郎、脇田隆字、相崎英樹
- Organizer
  第26回抗ウイルス療法学会総会
- Place of Presentation
  名古屋
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] 感染細胞の超微形態変化（SVR 後も含めて）2016
- Author(s)
  相崎英樹
- Organizer
  (公財)宮川庚子記念研究財団研修会
- Place of Presentation
  東京
- Year and Date
  2016-02-13
- Invited
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Cilnidipine inhibits the early phase of HBV infection in a NTCP independent mechanism.2015
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Tanaka Y, Wakita T.
- Organizer
  International Meeting, Molecular Biology of Hepatitis B Viruses.
- Place of Presentation
  Dolce Bad Nauheim, Germany
- Year and Date
  2015-10-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Identification of a flavonoid derivative that directly acts on hepatitis B virus surface protein and inhibits viral entry.2015
- Author(s)
  Tsukuda S, Watashi K, Hamada Y, Isogawa M, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Saito A, Tanaka Y, Mizokami M, Wakita T.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Identification of NTCP-targeting small molecules that inhibit HBV entry by cell-based and in vitro technologies.2015
- Author(s)
  Watashi K, Tsukuda S, Shimura S, Kaneko M, Sluder A, Peel M, Kamisuki S, Matsunaga S, Morishita R, Futamura Y, Kondoh Y, Suzuki R, Aizaki H, Sugiyama M, Borroto-Esoda K, Ryo A, Sugawara F, Osada H, Tanaka Y, Mizokami M, Wakita T.
- Organizer
  2015 International Meeting, Molecular Biology of Hepatitis B Viruses.
- Place of Presentation
  Dolce Bad Nauheim, Germany
- Year and Date
  2015-10-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicit neutralizing antibodies against JEV and Hepatitis C virus.2015
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Tajima S, Takasaki T, Takeyama H, Wakita T, Suzuki R.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Prolactin regulatory element binding protein promotes the formation of HCV membranes replication compartment by interacting with NS4B.2015
- Author(s)
  Kong L, Fujimoto A, Aoyagi H, Matsuda M, Watashi K, Suzuki R, Yamagoe S, Dohmae N, Suzuki T, Suzuki T, Wakita T, Aizaki H.
- Organizer
  International Symposium on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Strasbourg, France
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Transfer hepatitis C virus between human liver cells and hepatic stellate cells.2015
- Author(s)
  Aizaki H.
- Organizer
  The 2015 Italy-Japan Liver Workshop
- Place of Presentation
  Italy
- Year and Date
  2015-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Cilnidipine inhibits the early phase of HBV infection in a NTCP independent mechanism.2015
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Tanaka Y, Wakita T.
- Organizer
  2015 International Meeting, Molecular Biology of Hepatitis B Viruses.
- Place of Presentation
  Dolce Bad Nauheim, Germany
- Year and Date
  2015-10-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Surfeit 4 is involved in HCV replication by interacting with NS4B.2015
- Author(s)
  Lingbao K, Aoyagi H, Matsuda M, Fujimoto A, Watashi K, Suzuki R, Yamagoe S, Dohmae N, Sakamaki Y, Ichinose S, Suzuki T, Wakita T, Aizaki H.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] HCV複製複合体を含む膜小胞の形成メカニズムの解析2015
- Author(s)
  相崎英樹、脇田隆字.
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] B型肝炎ウイルスに対する直接標的薬proanthocyanidinおよび宿主標的薬vanitalacinの感染阻害効果および作用機序の解析.2015
- Author(s)
  渡士幸一、九十田千子、金子学、松永大輝、紙透伸治、齊藤安貴子、鈴木亮介、相崎英樹、杉山真也、溝上雅史、菅原二三男、田中靖人、脇田隆字.
- Organizer
  第25回抗ウイルス療法学会総会、
- Place of Presentation
  東京
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Development of a novel vaccine platform based on Japanese encephalitis viruses.2015
- Author(s)
  Suzuki R, Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Tajima S, Takasaki T, Takeyama H, Wakita T.
- Organizer
  日本分子生物学会第38回年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Identification of NTCP-targeting small molecules that inhibit HBV entry by cell-based and in vitro technologies.2015
- Author(s)
  Watashi K, Tsukuda S, Shimura S, Kaneko M, Sluder A, Peel M, Kamisuki S, Matsunaga S, Morishita R, Futamura Y, Kondoh Y, Suzuki R, Aizaki H, Sugiyama M, Borroto-Esoda K, Ryo A, Sugawara F, Osada H, Tanaka Y, Mizokami M, Wakita T.
- Organizer
  International Meeting, Molecular Biology of Hepatitis B Viruses.
- Place of Presentation
  Dolce Bad Nauheim, Germany
- Year and Date
  2015-10-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Identification of a new tricyclic polyketide, vanitaracin A, which inhibits the entry of HBV, HDV, and nucleoside analog-resistant HBV 　through targeting NTCP.2015
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Mtsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Sam-Yong P, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T.
- Organizer
  International Meeting, Molecular Biology of Hepatitis B Viruses.
- Place of Presentation
  Dolce Bad Nauheim, Germany
- Year and Date
  2015-10-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Identification of a new tricyclic polyketide, vanitaracin A, which inhibits the entry of HBV, HDV, and nucleoside analog-resistant HBV 　through targeting NTCP.2015
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Mtsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Sam-Yong P, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T.
- Organizer
  2015 International Meeting, Molecular Biology of Hepatitis B Viruses.
- Place of Presentation
  Dolce Bad Nauheim, Germany
- Year and Date
  2015-10-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] A new fungi-derived vanitaracin A specifically inhibits the entry of hepatitis B and D viruses through interacting with NTCP.2015
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai H, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Sam-Yong P, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Wakita T.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicit neutralizing antibodies against JEV and Hepatitis C virus.2015
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Tajima S, Takasaki T, Takeyama H, Wakita T, Suzuki R.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] B型肝炎ウイルスに対する直接標的薬proanthocyanidinおよび宿主標的薬vanitalacinの感染阻害効果および作用機序の解析.2015
- Author(s)
  渡士幸一、九十田千子、金子学、松永大輝、紙透伸治、齊藤安貴子、鈴木亮介、相崎英樹、杉山真也、溝上雅史、菅原二三男、田中靖人、脇田隆字.
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Transfer Hepatitis C virus from human liver cells to hepatic stellate cells.2015
- Author(s)
  Zaitsu T, Aoyagi H, Fujimoto A, Matsuda M, Watanabe N, Watashi K, Suzuki R, Fukuhara T, Matsuura Y, Sakamaki Y, Ichinose S, Wake K, Suzuki T, Iijima H, Matsuura T, Tamura K, Wakita T, Aizaki H.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Japanese encephalitis virus (JEV)-subviral particles harboring HCV neutralization epitopes elicit neutralizing antibodies against JEV and HCV.2015
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Takeyama H, Wakita T, Suzuki R.
- Organizer
  International Symposium on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Strasbourg, France
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Prolactin regulatory element binding protein promotes the formation of HCV membranes replication compartment by interacting with NS4B.2015
- Author(s)
  Kong L, Fujimoto A, Aoyagi H, Matsuda M, Watashi K, Suzuki R, Yamagoe S, Dohmae N, Suzuki T, Suzuki T, Wakita T, Aizaki H.
- Organizer
  22nd International Symposium on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Strasbourg, France
- Year and Date
  2015-10-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] 肝炎ウイルス検査陽性者アンケート調査の受診勧奨効果2015
- Author(s)
  中野卓二、橋本千樹、川部直人、村尾道人、嶋崎宏明、菅敏樹、中岡和徳、高川友花、大城昌史、高村知希、野村小百合、吉岡健太郎、中田佳穂里、青山政美、片岡博喜、相崎英樹、是永匡紹.
- Organizer
  第41回日本肝臓学会西部会
- Place of Presentation
  名古屋
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Neoechinulin Bのliver X receptor転写阻害効果の同定およびそれによるC型肝炎ウイルス複製制御機構の解析.2015
- Author(s)
  渡士幸一、中嶋翔、紙透伸治、Jesus Izaguirre-Carbonell、Andrew Tae-Jun Kwon、鈴木治和、九十田千子、岡田麻衣子、鈴木亮介、相崎英樹、菅原二三男、脇田隆字.
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] 肝炎ウイルス検査陽性者アンケート調査の受診勧奨効果2015
- Author(s)
  中野卓二、橋本千樹、川部直人、村尾道人、嶋崎宏明、菅敏樹、中岡和徳、高川友花、大城昌史、高村知希、野村小百合、吉岡健太郎、中田佳穂里、青山政美、片岡博喜、相崎英樹、是永匡紹.
- Organizer
  第41回日本肝臓学会西部会
- Place of Presentation
  名古屋
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] HCV複製複合体を含む膜小胞の形成メカニズムの解析.2015
- Author(s)
  相崎英樹、脇田隆字.
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Neoechinulin Bのliver X receptor転写阻害効果の同定およびそれによるC型肝炎ウイルス複製制御機構の解析.2015
- Author(s)
  渡士幸一、中嶋翔、紙透伸治、Jesus Izaguirre-Carbonell、Andrew Tae-Jun Kwon、鈴木治和、九十田千子、岡田麻衣子、鈴木亮介、相崎英樹、菅原二三男、脇田隆字
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Multimerization of hepatitis B virus core protein regulated by microtubules.2015
- Author(s)
  Iwamoto M, Watashi K, Sugiyama M, Suzuki R, Aizaki H, Tanaka Y, Mizokami M, Ohtani N, Koiwai O, Wakita T.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Multimerization of hepatitis B virus core protein regulated by microtubules.2015
- Author(s)
  Iwamoto M, Watashi K, Sugiyama M, Suzuki R, Aizaki H, Tanaka Y, Mizokami M, Ohtani N, Koiwai O, Wakita T.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Flutamide-mediated Disruption of Lipid Droplets Impairs the Host Permissiveness to Hepatitis C virus Production.2015
- Author(s)
  Ohashi H, Watashi K, Nakajima S, Sulyi K, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Wakita T.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Japanese encephalitis virus (JEV)-subviral particles harboring HCV neutralization epitopes elicit neutralizing antibodies against JEV and HCV.2015
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Takeyama H, Wakita T, Suzuki R.
- Organizer
  22nd International Symposium on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Strasbourg, France
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] 新規真菌二次代謝産物 SF177 の B 型肝炎ウイルス感染阻害活性および NTCP トランスポーター阻害活性の同定.2015
- Author(s)
  金子学, 渡士幸一，紙透伸治, 岩本将士，河合文啓, 鈴木亮介，相崎英樹，朴三用, 菅原二三男, 脇田隆字.
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Surfeit 4 is involved in HCV replication by interacting with NS4B.2015
- Author(s)
  Lingbao K, Aoyagi H, Matsuda M, Fujimoto A, Watashi K, Suzuki R, Yamagoe S, Dohmae N, Sakamaki Y, Ichinose S, Suzuki T, Wakita T, Aizaki H.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] 新規真菌二次代謝産物 SF177 の B 型肝炎ウイルス感染阻害活性および NTCP トランスポーター阻害活性の同定.2015
- Author(s)
  金子学, 渡士幸一，紙透伸治, 岩本将士，河合文啓, 鈴木亮介，相崎英樹，朴三用, 菅原二三男, 脇田隆字.
- Organizer
  第25回抗ウイルス療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Transfer Hepatitis C virus from human liver cells to hepatic stellate cells.2015
- Author(s)
  Zaitsu T, Aoyagi H, Fujimoto A, Matsuda M, Watanabe N, Watashi K, Suzuki R, Fukuhara T, Matsuura Y, Sakamaki Y, Ichinose S, Wake K, Suzuki T, Iijima H, Matsuura T, Tamura K, Wakita T, Aizaki H.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Development of a novel vaccine platform based on Japanese encephalitis viruses.2015
- Author(s)
  Suzuki R, Saga R, Fujimoto A, Watanabe N, Matsuda M, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Tajima S, Takasaki T, Takeyama H, Wakita T.
- Organizer
  日本分子生物学会第38回年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Flutamide-mediated Disruption of Lipid Droplets Impairs the Host Permissiveness to Hepatitis C virus Production.2015
- Author(s)
  Ohashi H, Watashi K, Nakajima S, Sulyi K, Suzuki R, Aizaki H, Fukasawa M, Kamisuki S, Sugawara F, Ohtani N, Wakita T.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Transfer hepatitis C virus between human liver cells and hepatic stellate cells.2015
- Author(s)
  Aizaki H.
- Organizer
  The 2015 Italy-Japan Liver Workshop
- Place of Presentation
  Italy
- Year and Date
  2015-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] A new fungi-derived vanitaracin A specifically inhibits the entry of hepatitis B and D viruses through interacting with NTCP.2015
- Author(s)
  Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai H, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Sam-Yong P, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Wakita T.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K09034
[Presentation] Identification of a flavonoid derivative that directly acts on hepatitis B virus surface protein and inhibits viral entry.2015
- Author(s)
  Tsukuda S, Watashi K, Hamada Y, Isogawa M, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Saito A, Tanaka Y, Mizokami M, Wakita T.
- Organizer
  日本ウイルス学会第63回学術集会
- Place of Presentation
  福岡
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] ヒトNTCP安定発現によるB型肝炎ウイルス(HBV)感染許容性の獲得とそれを用いたHBV侵入機構の解析2014
- Author(s)
  岩本将士、渡士幸一、九十田千子、Hussein Aly、藤本陽、鈴木亮介、相崎英樹、脇田隆字、深澤征義、小祝修、楠原洋之
- Organizer
  第22回肝病態生理研究会
- Place of Presentation
  東京
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Dynamic metabolomics change in HCV-infected cells,2013
- Author(s)
  Aizaki H
- Organizer
  The 2013 Italy- Japan Liver Workshop“Hepatitis, Steatosis and Hepatocellular Carcinoma: molecular basis and clinical links”
- Place of Presentation
  Italy
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] C型肝炎ウイルスNS5A結合タンパク質ELAVL1のウイルス複製・翻訳スイッチング機構の解析2013
- Author(s)
  後藤耕司、相崎英樹、渡邉則幸、渡士幸一、鈴木亮介、山越智、四柳宏、森屋恭爾、小池和彦、鈴木哲朗、宮村達男、脇田隆字
- Organizer
  日本ウイルス学会第61回学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] エンベロープペプチドを用いたHCV感染に重要なアミノ酸領域の探索2013
- Author(s)
  渡邉則幸, 伊達朋子、相崎英樹、脇田隆字
- Organizer
  日本ウイルス学会第61回学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Antiviral activity of glycyrrhizin against hepatitis C virus in vitro2013
- Author(s)
  Aoyagi H, Aizaki H, Matsumoto Y, Matsuda M, Hmwe SS, Watanabe N, Watashi K, SuzukiR,IchinoseS,MatsuuraT,SuzukiT, -79- Wake K, Miyamura T, Wakita T.
- Organizer
  The 12th Awaji international forum on infection and immunity
- Place of Presentation
  Awaji
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] プラスミドトランスフェクションによるトランスパッケージング型1回感染性フラビウイルス産生系の確立.2013
- Author(s)
  鈴木亮介、石川知弘、小西英二、嵯峨涼平、松田麻未、渡士幸一、相崎英樹、高崎智彦、脇田隆字
- Organizer
  日本分子生物学会第36回年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Analysis of bioactivity of fungal-derived natural products based on a virus infection system2013
- Author(s)
  Nakajima S, Watashi K, Kamisuki S, TakemotoK,SuzukiR,AizakiH,SugawaraF,Wakita T
- Organizer
  The 2nd International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Interleukin-1 and tumor necrosis factor-alpha trigger restriction of hepatitis B virus infection via a cytidine deaminase AID.2013
- Author(s)
  Watashi K, Liang G, Iwamoto M, Marusawa H, Kitamura K, Muramatsu M, Suzuki R, Li J, Tong S, Tanaka Y, Murata K, Aizaki H, Wakita T.
- Organizer
  2013 International Meeting on Molecular Biology of Hepatitis B viruses
- Place of Presentation
  Shanghai, China.
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Identification of a natural product inhibiting the transcriptional activity of liver X receptor and reducing the production of infectious HCV2013
- Author(s)
  Nakajima S, Watashi K, Kamisuki S, TakemotoK,SuzukiR,AizakiH,SugawaraF, Wakita T
- Organizer
  20th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] 当院で経験した、HIV陽性者における急性C型肝炎の集団発生について2013
- Author(s)
  井戸田一朗、加藤康幸、青柳東代、相崎英樹、脇田隆字
- Organizer
  第27 回日本エイズ学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Dynamics of the cellular metabolome during hepatitis C virus infection: Regulation of the lipoprotein metabolisms by hepatic lipase.2013
- Author(s)
  Fujimoto A, Aizaki H, Matsuda M, Watanabe N, Watashi K, Suzuki R, Suzuki T, Miyamura T, Wakita T
- Organizer
  20th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] C型肝炎ウイルス分泌過程はphospholipase Dが関わる膜輸送により制御される2013
- Author(s)
  内田奈々子、渡士幸一、中嶋翔、岩本将士、鈴木亮介、相崎英樹、千葉丈、脇田隆字
- Organizer
  日本ウイルス学会第61回学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Mechanistic analysis on hepatitis B virus entry in an NTCP-overexpressing cell line.2013
- Author(s)
  Iwamoto M, Watashi K, Tsukuda S, Aly HH, Suzuki R, Aizaki H, Koiwai H, Kusuhara H, Wakita T
- Organizer
  2013 International Meeting on the Molecular Biology of Hepatitis B Viruses.
- Place of Presentation
  Shanghai, China.
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] IL-1/TNFaによるシチジンデアミナーゼAID誘導を介したB型肝炎ウイルス感染排除機構2013
- Author(s)
  渡士幸一、Guoxin Liang、岩本将士、丸澤宏之、喜多村晃一、村松正道、鈴木亮介、相崎英樹、脇田隆字
- Organizer
  日本ウイルス学会第61回学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Regulation of Hepatitis C virus (HCV) release by phospholipase A2 and autophagy -Antiviral Activity of Glycyrrhizin against HCV2013
- Author(s)
  Aoyagi H, Aizaki H, Matsumoto Y, Matsuda M, Hmwe SS, Watanabe N, Watashi K, Suzuki R, Ichinose S, Matsuura T, Suzuki T, Wake K, Miyamura T, Wakita T.
- Organizer
  日本分子生物学会第36回年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Liver X Receptor 転写活性および感染性C型肝炎ウイルス粒子産生を阻害する天然有機化合物の同定2013
- Author(s)
  中嶋翔、渡士幸一、紙透伸治、竹本健二、鈴木亮介、相崎英樹、菅原二三男、脇田隆字
- Organizer
  日本ウイルス学会第61回学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Hepatitis C virus RNA replication in human stellate cells regulates gene expression of extracellular matrix-related molecules2013
- Author(s)
  Aizaki H, Watanabe N, Aoyagi H, Hmwe SS, Watashi K, Suzuki R, Kojima S, Matsuura T, Wake K, Miyamura T, Suzuki T, Wakita T
- Organizer
  International Symposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] 細胞内発現抗体 (イントラボディ)によるC型肝炎ウイルスの増殖抑制.2013
- Author(s)
  松田麻未、斎藤憲司、鈴木亮介、佐藤充、鐘ヶ江裕美、渡士幸一、相崎英樹、千葉丈、斎藤泉、脇田隆字、鈴木哲朗.
- Organizer
  日本ウイルス学会第61回学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] HCV NS3 protease plus TNF-α promotes liver fibrosis via stimulating expression and activation of TGF-β type I receptor2013
- Author(s)
  Sakata K, Hara M, Terada T, Watanabe N, Yaguchi S, Matsumoto M, Shirouzu M, Yokoyama S, Miyazawa K, Aizaki H, Suzuki T, Wakita T,Kojima S
- Organizer
  第20回肝細胞研究会
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] B型肝炎ウイルス侵入阻害剤の同定およびそのNTCPを介した感染阻害機構の解明2013
- Author(s)
  九十田千子、渡士幸一、岩本将士、鈴木亮介、相崎英樹、小嶋聡一、脇田隆字
- Organizer
  日本ウイルス学会第61回学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] C型肝炎ウイルス感染による宿主細胞の脂質代謝変化とHepatic Lipase発現制御2013
- Author(s)
  藤本陽, 相崎英樹, 松田麻未, 渡邉則幸, 渡士幸一, 鈴木亮介, 鈴木哲朗, 宮村達男, 脇田隆字
- Organizer
  日本ウイルス学会第61回学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] A Retinoid Derivative Inhibits Hepatitis B Virus Entry Mediated by NTCP.2013
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Wakita T.
- Organizer
  International Meeting on Molecular Biology of Hepatitis B Viruses.
- Place of Presentation
  Shanghai, China.
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Production of single-round infectious chimeric flaviviruses with a DNA-based Japanese encephalitis virus replicon.2013
- Author(s)
  Suzuki R, Konishi E, Ishikawa T, Matsuda M, Watashi K, Aizaki H, Takasaki T, WakitaT.
- Organizer
  Keystone Symposia, Positive Strand RNA Viruses
- Place of Presentation
  Boston, U.S.A.
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Comprehensive and comparative proteomics reveals alterations of metabolomics between monolayer and three- dimensional cell cultures.2013
- Author(s)
  agamori S, Aizaki H, Matsumoto Y, Isozumi N, Wiriyasermkul P, Matsuura T, Kanai Y
- Organizer
  12th Human Proteome Organization World Congress 2013.
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] ヒトNTCP安定発現細胞株におけるB型肝炎ウイルス侵入機構の解析2013
- Author(s)
  岩本将士、渡士幸一、九十田千子、 Hussein Hassan Aly、鈴木亮介、相崎英樹、小祝修、楠原洋之、脇田隆字
- Organizer
  日本ウイルス学会第61回学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Phospholipase A2およびAutophagyによるC型肝炎ウイルス(HCV)分泌過程の制御 ― グリチルリチンによる抗HCV作用―2013
- Author(s)
  青柳東代, 相崎英樹, 藤本陽, 松本喜弘, 松田麻未, Su Su Hmwe,渡邉則幸, 渡士幸一, 鈴木亮介, 市野瀬志津子, 松浦知和, 鈴木哲朗, 和氣健二郎, 宮村達男, 脇田隆字.
- Organizer
  日本ウイルス学会第 61回学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Independent evolution of multi-dominant viral genome species observed in a single HCV carrier.2012
- Author(s)
  Ando T, Aizaki H, Sugiyama M, Mizokami M, Kuroda M, Wakita T.
- Organizer
  International Meeting on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Italy
- Invited
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Neutralizing antibodiesninduced by cell cultute-derived Hepatitis C virus was effective both in vitro and in vivo.2012
- Author(s)
  Akazawa D, Moriyama M, Yokokawa N, Watanabe N, Date T, Morikawa K, Aizaki H, Ishii K, Kato T, Nakamura N, Wakita T.
- Organizer
  19th International Meeting on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Italy
- Invited
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] HCV粒子形成に関与する宿主因子の同定と解析2012
- Author(s)
  相崎　英樹
- Organizer
  平成24年度遺伝子病制御研究所研究集会　感染・免疫・炎症・発癌
- Place of Presentation
  北海道大学（北海道）
- Data Source
  KAKENHI-PROJECT-23390202
[Presentation] NS3 protease derived from genotype 1b Con1 attenuates viral replication.2012
- Author(s)
  Kim S, Date T, Aizaki H, Watanabe H, Wakita T.
- Organizer
  19th International Meeting on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Italy
- Invited
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Characterization of anti-HCV release inhibitors targeting phospholipase D.2012
- Author(s)
  atashi K, Uchida N, Saeed M, Suzuki R, Aizaki H, Wakita T.
- Organizer
  19th International Meeting on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Italy
- Invited
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Antiviral activity of glycyrrhizin against Hepatitis C virus in vitro.2012
- Author(s)
  Matsumoto Y, Watanabe N, Watashi K, Suzuki R, Matsuura T, Suzuki T, Miyaura T, Wake K, Wakita T, Aizaki H.
- Organizer
  19th International Meeting on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  Italy
- Invited
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] C型肝炎ウイルスNS3プロテアーゼによるTGF-βI型受容体を介したTGF-βシグナルの活性化2011
- Author(s)
  坂田幸大郎、原詳子、鈴木哲朗、渡邊則幸、相崎英樹、高谷大輔、松本武久、井本正哉、脇田隆字、小嶋聡一
- Organizer
  第25回肝類洞壁細胞研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] HCV NS3 Protease Mimics TGF-□2 and Activates TGF-□ Signals via Type I Receptor2011
- Author(s)
  坂田幸大郎、原詳子、鈴木哲朗、渡邊則幸、相崎英樹、高谷大輔、松本武久、井本正哉、脇田隆字、小嶋聡一
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] ヒト肝細胞癌細胞の3次元培養系は"肝癌モデル"なのか、"肝臓モデル"なのか?-glucose代謝からの検討-2011
- Author(s)
  松浦知和、丸島秀樹、前橋はるか、大川清、松本善弘、永妻啓介、田中賢、高木一郎、石井雄二、斎藤勝也、政木隆博、相崎英樹
- Organizer
  第47回日本肝臓学会総会・シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Identification and functional analysis of small molecules inhibiting the late step of hepatitis C virus life cycle2011
- Author(s)
  Watashi K, Uchida N, Suzuki R, Aizaki H, Wakita T
- Organizer
  18^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  WA, USA
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Identification of novel NS5A-associated proteins in the host-cell membrane fraction and their role in HCV life cycle2011
- Author(s)
  Goto K, Kimura T, Watashi K, Suzuki R, Yamagoe S, Miyamura T, Moriya K, Yotsuyanagi H, Koike K, Suzuki T, Wakita T, Aizaki H
- Organizer
  18^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  WA, USA
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Screening of small molecules affecting the production of hepatitis B virus2011
- Author(s)
  Watashi K, Uchida N, Suzuki R, Aizaki H, Wakita T
- Organizer
  International meeting of molwcular biology of hepatitis B virus
- Place of Presentation
  Florida, USA
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Discovery of full-length HCV genome quasispecies by deep sequencing2011
- Author(s)
  Ando T, Aizaki H, Sugiyama M, Mizokami M, Sekizuka T, Kuroda M, Wakita T
- Organizer
  18^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  WA, USA
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Discovery of full-length HCV genome quasispecies by deep sequencing2011
- Author(s)
  Ando T, Aizaki H, Sugiyama M, Mizokami M, Sekizuka T, Kuroda M, Wakita T
- Organizer
  18^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  米国ワシントン州
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] 1999年から2009年における日本のC型急性肝炎の発生状況2011
- Author(s)
  相崎英樹、多田有希、松本善弘、後藤耕司、渡士幸一、鈴木亮介、田中純子、鈴木哲朗、岡部信彦、脇田隆字
- Organizer
  第47回日本肝臓学会総会・シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Screening of small molecules affecting the production of hepatitis B virus2011
- Author(s)
  Watashi K, Uchida N, Suzuki R, Aizaki H, Wakita T
- Organizer
  International meeting of molecular biology of hepatitis B virus
- Place of Presentation
  米国フロリダ州
- Year and Date
  2011-10-10
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] ヒト肝細胞癌細胞の3次元培養系は"癌モデル"なのか、"肝臓モデル"なのか?-glucose代謝からの検討-2011
- Author(s)
  松浦知和、丸島秀樹、前橋はるか、大川清、松本善弘、永妻啓介、田中賢、高木一郎、石井雄二、斎藤勝也、政木隆博、相崎英樹
- Organizer
  第47回日本肝臓学会総会・シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Identification and functional analysis of small molecules inhibiting the late step of hepatitis C virus life cycle2011
- Author(s)
  Watashi K, Uchida N, Suzuki R, Aizaki H, Wakita T
- Organizer
  18^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  米国ワシントン州
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] HCV感染に伴う宿主細胞の脂質代謝の変化と代謝産物のメタボロミクス解析2011
- Author(s)
  相崎英樹、鈴木哲朗、脇田隆字
- Organizer
  第47回日本肝臓学会総会・シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] C型肝炎ウイルス研究の進歩と展望2011
- Author(s)
  相崎英樹
- Organizer
  第58回日本感染症学会総会・学術講演会・教育講演
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Identification of lipid droplet-associated membrane proteins that are involved in HCV production2011
- Author(s)
  相崎英樹, ほか
- Organizer
  18^<th> Int Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  シアトル(米国)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-23390202
[Presentation] HCV NS3Protease Mimics TGF-・2and Activates TGF-・Signals via Type I Receptor2011
- Author(s)
  坂田幸大郎、原詳子、鈴木哲朗、渡邊則幸、相崎英樹、高谷大輔、松本武久、井本正哉、脇田隆字、小嶋聡一
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Signal peptidase complex 1 participates in the assembly of hepatitis C virus through an interaction with NS22011
- Author(s)
  Suzuki R, Suzuki T, Saito K, Matsuda M, Watashi K, Mat suura Y, Wakita T, Aizaki H
- Organizer
  18^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  米国ワシントン州
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Identification of lipid droplet-associated membrane proteins that are involved in HCV production2011
- Author(s)
  Aizaki H, Matsumoto Y, Goto K, Watashi K, Suzuki R, Fukasawa M, Hanada K, Sato S, Takahashi N, Matsuura Y, Motojima K, Miyamura T, Suzuki T, WakitaT
- Organizer
  18^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  WA, USA
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Identification of novel NS5A-associated proteins in the host-cell membrane fraction and their role in HCV life cycle2011
- Author(s)
  Goto K, Kimura T, Watashi K, Suzuki R, Yamagoe S, Miyamura T, Moriya K, Yotsuyanagi H, Koike K, Suzuki T, Wakita T, Aizaki H
- Organizer
  18^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  米国ワシントン州
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] 国内献血検体を用いたC型肝炎ウイルスパネル検体の作製とウイルス量測定法の評価2011
- Author(s)
  加藤考宣、村上麻子、政木隆博、相崎英樹
- Organizer
  第47回日本肝臓学会総会・シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Halopemide inhibited a post-assembly step in hepatitis C virus life cycle2011
- Author(s)
  Uchida N, Watashi K, Suzuki R, Aizaki H, Chiba J, Wakita T
- Organizer
  18^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  WA, USA
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Identification of host factor that interacts with hepatitis C virus NS2 protein and is involved in the viral assembly2011
- Author(s)
  Suzuki R, Suzuki T, Saito K, Matsuda M, Watashi K, Matsuura Y, Wakita K, Aizaki H
- Organizer
  XV International Congress of Virology
- Place of Presentation
  札幌
- Year and Date
  2011-10-10
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Identification of lipid droplet-associated membrane proteins that are involved in HCV production2011
- Author(s)
  Aizaki H, Matsumoto Y, Goto K, Watashi K, Suzuki R, Fukasawa M, Hanada K, Sato S, Takahashi N, Matsuura Y, Motojima K, Miyamura T, Suzuki T, Wakita T
- Organizer
  18^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  米国ワシントン州
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Identification of host factor that interacts with hepatitis C virus NS2 protein and is involved in the viral assembly2011
- Author(s)
  Suzuki R, Suzuki T, Saito K, Matsuda M, Watashi K, Matsuura Y, Wakita K, Aizaki H
- Organizer
  XV International Congress of Virology
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Signal peptidase complex 1 participates in the assembly of hepatitis C virus through an interaction with NS22011
- Author(s)
  Suzuki R, Suzuki T, Saito K, Matsuda M, Watashi K, Matsuura Y, Wakita T, Aizaki H
- Organizer
  18^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  WA, USA
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Halopemide inhibited a post-assembly step in hepatitis C virus life cycle2011
- Author(s)
  Uchida N, Watashi K, Suzuki R, Aizaki H, Chiba J, Wakita T
- Organizer
  18^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  米国ワシントン州
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Squalane synthase阻害剤のC型肝炎ウイルス増殖阻害機構の解析2010
- Author(s)
  斎藤恭子、鈴木哲朗、相崎英樹、花田賢太郎、脇田隆字、西島正弘、深澤征義
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] HCV粒子形成に関与する脂肪滴周辺膜蛋白の機能解析2010
- Author(s)
  相崎英樹, 他
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  ホテルメトロポリタン山形(山形県)
- Data Source
  KAKENHI-PUBLICLY-21022051
[Presentation] Real-time visualization of the ATP level in HCV replicating cells2010
- Author(s)
  Ando T, Imamura H, Suzuki R, Aizaki H, Wakita T, Suzuki T
- Organizer
  17th International meeting on hepatitis C virus and related viruses
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] HCV粒子形成と脂質の役割2010
- Author(s)
  相崎英樹
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Inhibition of cellular squalene synthase impairs hepatitis Cvirus proliferation in cultured cells2010
- Author(s)
  Saito K, Suzuki T, Aizaki H, Hanada K, Wakita T, Nishijima M, Fukasawa M
- Organizer
  17^<th> International meeting on hepatitis Cvirus and related viruses
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Real-time visualization of the ATP level in HCV replicating cells2010
- Author(s)
  Ando T, Imamura H, Suzuki R, Aizaki H, Wakita T, Suzuki T
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] 分割ユビキチン法を利用したHCVNS2と結合する宿主因子の探索およびウイルス粒子形成への関与2010
- Author(s)
  鈴木亮介、相崎英樹、脇田隆字、鈴木哲朗
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] C型肝炎ウイルス複製複合体におけるATP制御の可視化と機能解析2010
- Author(s)
  安東友美、今村博臣、鈴木亮介、相崎英樹、脇田隆字、鈴木哲朗
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Real-time visualization of the ATP level in HCV replicating cells2010
- Author(s)
  ndo T, Imamura H, Suzuki R, Aizaki H, Wakita T, Suzuki T
- Organizer
  17^<th> International meeting on hepatitis Cvirus and related viruses
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] C型肝炎ウイルス粒子感染における粒子表面のコレステロールの役割2010
- Author(s)
  山本真民、相崎英樹、脇田隆字、鈴木哲朗
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] CVエンベロープタンパク質に付加されるN型糖鎖の機能解析2010
- Author(s)
  渡辺則幸、村山麻子、Saeed Mohsan、伊達朋子、加藤孝宣、相崎英樹、脇田隆字
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] HCVエンベロープタンパク質に付加されるN型糖鎖の機能解析2010
- Author(s)
  渡辺則幸、村山麻子, Saeed Mohsan、伊達朋子、加藤孝宣、相崎英樹、脇田隆字
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] HCV粒子形成に関与する脂肪滴周辺膜蛋白の機能解析2010
- Author(s)
  相崎英樹
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] 生体膜脂質のC型肝炎ウイルス生活環における役割2009
- Author(s)
  相崎英樹
- Organizer
  第31回日本膜学会、シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] HCV粒子形成に関与する脂肪滴周辺膜蛋白の同定と機能解析2009
- Author(s)
  相崎英樹、後藤耕司、山本真民、佐藤慈子、高橋信弘、深澤征義、花田賢太郎、松浦善治、宮村達男、脇田隆字、鈴木哲朗
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] HCV粒子形成に関与する脂肪滴周辺膜蛋白の同定2009
- Author(s)
  相崎英樹, 他
- Organizer
  日本ウイルス学会第57回学術集会、ワークシヨップ7
- Place of Presentation
  都市センターホテル
- Data Source
  KAKENHI-PUBLICLY-21022051
[Presentation] Identification of lipid droplet-associated membrane proteins that are involved in HCV production2009
- Author(s)
  H Aizaki, 他
- Organizer
  16th lnternational Meeting on Hepatitis C and Related Viruses
- Place of Presentation
  Nice, France
- Data Source
  KAKENHI-PUBLICLY-21022051
[Presentation] 感染性HCV粒子形成における宿主生体膜の役割2009
- Author(s)
  相崎英樹、脇旦隆字
- Organizer
  第45回日本肝臓学会総会、シンポジウム1
- Place of Presentation
  神戸ポートピアホテル
- Data Source
  KAKENHI-PUBLICLY-21022051
[Presentation] C型肝炎ウイルスsubgenomic replicon RNAを複製するヒト肝星細胞株の樹立2009
- Author(s)
  渡邉則幸、相崎英樹、松浦知和、脇田隆字、鈴木哲朗
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Identification of lipid droplet -associated membrane proteins that are involved in HCV production2009
- Author(s)
  Aizaki H, Yamamoto M, Goto K, Fukasawa M, Hanada K, Sato S, Takahashi N, Matsuura Y, Miyamura T, Wakita T, Suzuki T
- Organizer
  16th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Nice, France
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Structural requirements of virion-associated cholesterol for HCV morphogenesis and infectivity2009
- Author(s)
  Yamamoto M, Aizaki H, Goto K, Hamano K, Miyamura T, Wakita T, Suzuki T
- Organizer
  16th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Nice, France
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] C型肝炎ウイルス粒子形成、感染性に重要なコレステロール構造の解析2009
- Author(s)
  山本真民、相崎英樹、宮村達男、濱野国勝、脇田隆字、鈴木哲朗
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] 生体膜脂質のC型肝炎ウイルス生活環における役割2009
- Author(s)
  相崎英樹
- Organizer
  第31回日本膜学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] C型肝炎ウイルス粒子の脂質成分の感染における役割2009
- Author(s)
  相崎英樹、山本真民、後藤耕司、原弘道、森川賢一、谷英樹、松浦善治、斎藤恭子、深澤征義、花田賢太郎、西島正弘、宮村達男、脇田隆字、鈴木哲朗
- Organizer
  第16回肝細胞研究会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] C型肝炎ウイルス subgenomic replicon RNAを複製するヒト肝星細胞株の樹立2009
- Author(s)
  渡辺則幸、相崎英樹、松浦知和、脇田隆字、鈴木哲朗
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] 感染性HCV粒子形成における宿主生体膜の役割2009
- Author(s)
  相崎英樹、脇田隆字
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] 感染性HCV粒子形成における宿主生体膜の役割2009
- Author(s)
  相崎英樹、脇田隆字
- Organizer
  第45回日本肝臓学会総会、シンポジウム
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Structural requirement of virion-associated cholesterol for HCV morphogenesis and infectivity2009
- Author(s)
  Yamamoto M, Aizaki H, Goto K, Hamano K, Miyamura T, Wakita T, Suzuki T
- Organizer
  16^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Nice, France
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] HCV subgenomic replicon replication in human hepatic stellate cell lines2009
- Author(s)
  Watanabe N, Aizaki H, Matsuura T, Wakita T, Suzuki T
- Organizer
  16^<th> International Symposium on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Nice, France
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Identification of lipid droplet-associated membrane proteins that are involved in HCV production2009
- Author(s)
  Aizaki H, Yamamoto M, Goto K, Fukasawa M, Hanada K, Sato S, Takahashi N, Matsuura Y, Miyamura T, Wakita T, Suzuki T
- Organizer
  16^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Nice, France
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] HCV subgenomic replicon replication in human hepatic stellate cell lines2009
- Author(s)
  渡辺則幸, 相崎英樹, 松浦善治, 脇田隆字, 鈴木哲朗
- Organizer
  16th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Nice, France
- Data Source
  KAKENHI-PROJECT-21590867
[Presentation] Critical roles of virion-associated cholesterol and sphingolipids in the viral infectivity2008
- Author(s)
  H Aizaki, 他4名, K Hanada, Y Matsuura, M Lai, T Miyamura, T Wakita, T Suzuki
- Organizer
  XIVth International Congress of Virology
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2008-08-15
- Data Source
  KAKENHI-PROJECT-19041074
[Presentation] Critical roles of virion-associated cholesterol and sphingolipids in the viral infectivity2008
- Author(s)
  相崎英樹, 他
- Organizer
  XIVth International Congress of Virology, IUMS
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2008-08-15
- Data Source
  KAKENHI-PROJECT-19041074
[Presentation] The C-terminal serine of NS5A is a determinant of NS5A-core protein interaction and HCV production2008
- Author(s)
  Masaki R, Suzuki R, Murakami K, Aizaki H, Ishii K Miyamura T, Wakita T, Suzuki T.
- Organizer
  15th International Symposium on Hepatitis C Virus and Related Viruses.
- Place of Presentation
  SanAntonio, USA
- Data Source
  KAKENHI-PROJECT-19590799
[Presentation] HCV粒子形成におけるNS5A蛋白の役割2008
- Author(s)
  政木隆博、鈴木亮介、村上恭子、相崎英樹、石井孝司、村山麻子、伊達朋子、松浦善治、宮村達男、脇田隆字、鈴木哲朗
- Organizer
  日本ウイルス学会第56回学術集会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-18390225
[Presentation] creatine kinase BはC型肝炎ウイルスNS4Aとの相互作用によりウイルスゲノム複製複合体へ運ばれエネルギー供給に働く2008
- Author(s)
  原弘道、相崎英樹, 他5名、脇田隆字、鈴木哲朗
- Organizer
  日本ウイルス学会第56回学術集会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-19041074
[Presentation] Involvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A protein2008
- Author(s)
  Hara H, Aizaki H, Matsuda M, Murakami K, Shoji I, Miyamura T, Wakita T, Suzuki T.
- Organizer
  15th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  SanAntonio, USA
- Data Source
  KAKENHI-PROJECT-19590799
[Presentation] creatine kinase BはC型肝炎ウイルスNS4Aとの相互作用によりウイルスゲノム複製複合体へ運ばれエネルギー供給に働く2008
- Author(s)
  原弘道、相崎英樹、他5名、脇田隆字、鈴木哲朗
- Organizer
  日本ウイルス学会第56回学術集会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-18390225
[Presentation] HCV粒子形成におけるNS5A蛋白の役割2008
- Author(s)
  政木隆博、鈴木亮介、村上恭子、相崎英樹, 他5名、脇田隆字、鈴木哲朗
- Organizer
  日本ウイルス学会第56回学術集会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-19041074
[Presentation] C型肝炎ウイルスの生活環における脂質の役割に関する研究2008
- Author(s)
  相崎英樹、脇田隆字
- Organizer
  感染現象のマトリックス横糸の会
- Place of Presentation
  兵庫医科大学
- Data Source
  KAKENHI-PROJECT-19041074
[Presentation] C型肝炎ウイルスの生活環における脂質の役割に関する研究2008
- Author(s)
  相崎英樹, 他
- Organizer
  「感染現象のマトリックス」横糸の会
- Place of Presentation
  兵庫医科大学
- Data Source
  KAKENHI-PROJECT-19041074
[Presentation] 脂質のC型肝炎ウイルス感染における役割2008
- Author(s)
  相崎英樹, 他7名、花田賢太郎、宮村達男、脇田隆字、鈴木哲朗
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-19041074
[Presentation] 脂質のC型肝炎ウイルス感染、粒子形成における役割2007
- Author(s)
  相崎英樹, 他
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  ホテルグランパシフィックメリディアン
- Data Source
  KAKENHI-PROJECT-18015051
[Presentation] Critical roles of virion-associated cholesterol and sphingolipids in the viral infectivity2007
- Author(s)
  T Wakita, H Aizaki
- Organizer
  The 7th Awaji International Forum on Infection and Immunity, The Hyogo Prefecture Awaji Yumebutai International Conference Center
- Data Source
  KAKENHI-PROJECT-19041074
[Presentation] C型肝炎ウイルス脂質成分の感染における役割2007
- Author(s)
  相崎英樹、鈴木哲朗, 他
- Organizer
  第55回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590799
[Presentation] 脂質のC型肝炎ウイルス感染、粒子形成における役割2007
- Author(s)
  相崎英樹、原弘道、森川賢一、宮村達男、脇田隆字、鈴木哲朗
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590799
[Presentation] Critical roles of virion-associated cholesterol and sphingolipids in the viral infectivity.2007
- Author(s)
  Aizaki H, Suzuki T, et. al.
- Organizer
  14^<th> International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Glasgow,UK
- Data Source
  KAKENHI-PROJECT-19590799
[Presentation] The cholesterol and sphingolipids of hepatitis C virus particles play critical roles in the viral infectivity2007
- Author(s)
  Aizaki H, Fukasawa M, et. al.
- Organizer
  The 58^<th> annual meeting of the American association for the study of liver diseases
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-19590799
[Presentation] 脂質のC型肝炎ウイルス感染、粒子形成における役割2007
- Author(s)
  相崎英樹, 他
- Organizer
  第43回目本肝臓学会総会
- Place of Presentation
  ホテルグランパシフィックメリディアン
- Data Source
  KAKENHI-PROJECT-19041074
[Presentation] Critical roles of virion-associated cholesterol and sphingolipids in the viral infectivity2007
- Author(s)
  T Wakita, H Aizaki
- Organizer
  The 7^<th> Awaji International Forum on Infection and Immunity
- Place of Presentation
  The Hyogo Prefecture Awaji Yumebutai International Conference Center
- Data Source
  KAKENHI-PROJECT-18390225
[Presentation] 脂質のC型肝炎ウイルス感染、粒子形成における役割2007
- Author(s)
  相崎英樹, 他
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  ホテルグランパシフィックメリディアン
- Data Source
  KAKENHI-PROJECT-19659192
[Presentation] 脂質のC型肝炎ウイルス感染、粒子形成における役割2007
- Author(s)
  相崎英樹、原弘道、森川賢一、宮村達男、脇田隆字、鈴木哲朗
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  ホテルグランパシフィックメリディアン
- Data Source
  KAKENHI-PROJECT-19041074
[Presentation] 脂質のC型肝炎ウイルス感染、粒子形成における役割2007
- Author(s)
  相崎英樹、原弘道、森川賢一、宮村達男、脇田隆字、鈴木哲朗
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  ホテルグランパシフィックメリディアン
- Data Source
  KAKENHI-PROJECT-18390225
[Presentation] B 型肝炎ウイルス（HBV）large S タンパク質と NTCP の相互作用阻害による抗 HBV 戦略
- Author(s)
  渡士幸一、Sluder Ann、松永智子、梁明秀、森下了、岩本将士、九十田千子、鈴木亮介、相崎英樹、Borroto-Esoda Katyna、田中靖人、楠原洋之、杉山真也、溝上雅史、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] C型肝炎ウイルス粒子の構築を阻害するflutamideの作用機序の解析
- Author(s)
  大橋啓史、渡士幸一、中嶋翔、金ソルイ、鈴木亮介、相崎英樹、紙透伸治、菅原二三男、脇田隆字
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士吉田
- Year and Date
  2014-05-07 – 2014-05-09
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Prolactin regulatory element binding protein is involved in hepatitis C virus replication by interacting with NS4B.
- Author(s)
  Lingbao Kong、青柳春代、松田麻未、藤本陽、渡士幸一、鈴木亮介、山越智、堂前直、鈴木健裕、鈴木哲朗、脇田隆字、相崎英樹
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] C型肝炎ウイルス生活環全体を標的とした新規作用を有する抗ウイルス剤の探索
- Author(s)
  脇田隆字、相崎英樹、渡士幸一
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Characterization of a culture system reproducing the NTCP-mediated HBV entry and ITS application to drug development. 2014 International Meeting on Molecular Biology of Hepatitis B Viruses
- Author(s)
  Watashi K, Iwamoto M, Sluder A, Matsunaga S, Ryo A, Morishita R, Kwon ATJ, Suzuki H, Tsukuda S, Suzuki R, Aizaki H, Borroto-Esoda K, Sugiyama M, Tanaka Y, Mizokamai M, Wakita T.
- Organizer
  International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-03 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Microtubule-dependent hepatitis B virus (HBV) replication revealed by chemical screening on an efficient HBV-replicating cell line.
- Author(s)
  Iwamoto M, Watashi K, Sugiyama M, Suzuki R, Aizaki H, Tanaka Y, Mizokami M, Ohtani N, Koiwai O, Wakita T.
- Organizer
  International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-03 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Flutamide Inhibits Hepatitis C Virus Assembly through Disrupting Lipid Droplets.
- Author(s)
  Ohashi H, Watashi K, Nakajima S, Kim S, Suzuki R, Aizaki H, Kamisuki S, Sugawara F, Wakita T.
- Organizer
  21st International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Construction of novel infectious genotype 2b culture system.
- Author(s)
  Hmwe SS, Suda G, Sakamoto N, Imamura M, Hiraga N, Chayama K, Aizaki H, Wakita T.
- Organizer
  21st International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] 日本脳炎ウイルスおよび C 型肝炎ウイルス 2 価ワクチン抗原の発現と中和抗体の誘導
- Author(s)
  嵯峨涼平、藤本陽、渡邉則幸、松田麻未、長谷川慎、渡士幸一、相崎英樹、中村紀子、小西英二、加藤孝宣、田島茂、高崎智彦、竹山春子、脇田隆字、鈴木亮介
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Retinoid inhibitors abolish the host permissiveness to HBV infection by modulating NTCP expression.
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Tanaka Y, Mizokami M, Wakita T.
- Organizer
  International Meeting on the Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  Los Angeles (USA)
- Year and Date
  2014-09-03 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Single domain intrabodies against HCV core inhibit viral propagation and core-induced NF-kB activation.
- Author(s)
  Suzuki R, Saito K, Matsuda M, Sato M, Kanegae Y, Watashi K, Aizaki H, Chiba J, Saito I, Wakita T, Suzuki T.
- Organizer
  21st International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] 天然有機化合物 Neoechinulin B を利用した liver X receptor によるC 型肝炎ウイルス産生制御機構の解析
- Author(s)
  中嶋翔、渡士幸一、紙透伸治、竹本健二、Jesus Izaguirre-Carbonell、鈴木亮介、相崎英樹、菅原二三男、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Identification of an important envelope region by competitive inhibition experiment with envelope peptides.
- Author(s)
  Watanabe N, Date T, Kono T, Aizaki H, Wakita T.
- Organizer
  21st International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] B型肝炎ウイルス(HBV)Lタンパク質とNTCPの相互作用阻害による抗HBV戦略
- Author(s)
  渡士幸一、Ann Sluder、松永智子、梁明秀、森下了、岩本将士、九十田千子、鈴木亮介、相崎英樹、Katyna Borroto-Esoda、田中靖人、楠原洋之、杉山真也、溝上雅史、脇田隆字
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士吉田
- Year and Date
  2014-05-07 – 2014-06-09
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Retinoic acid receptor plays an important role in mediating hepatitis B virus infection through regulation of NTCP expression.
- Author(s)
  Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Kojima S, Sugiyama M, Tanaka Y, Mizokami M, Wakita T.
- Organizer
  The 11th JSH Single Topic Conference
- Place of Presentation
  広島
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] グリチルリチンによる抗C型肝炎ウイルス作用 - phospholipase A2およびAutophagyによるHCV分泌過程の制御
- Author(s)
  青柳東代、相崎英樹、松本喜弘、鈴木亮介、渡士幸一、市野瀬志津子、松浦知和、鈴木哲朗、和氣健二郎、脇田隆字
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] HBV感染受容体NTCPの発現調節機構の解析およびこれを阻害する低分子化合物の抗HBV効果
- Author(s)
  九十田千子、渡士幸一、岩本将士、鈴木亮介、相崎英樹、小嶋聡一、脇田隆字
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士吉田
- Year and Date
  2014-05-07 – 2014-05-09
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] 効率的な B 型肝炎ウイルス（HBV）複製評価系を用いた微小管依存的な HBV 複製機構の解析
- Author(s)
  岩本将士、渡士幸一、杉山真也、鈴木亮介、相崎英樹、田中靖人、溝上雅史、大谷直子、小祝修、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Regulation of viral lifecycle in hepatitis C virus infection.
- Author(s)
  Wakita T, Kong L, Aizaki H. Regulation of viral lifecycle in hepatitis C virus infection.
- Organizer
  Dynamic interplay between viruses and their hosts
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-08 – 2014-11-09
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] グリチルリチンによる抗HCV作用 - phospholipase A2およびAutophagyによるC型肝炎ウイルス(HCV)分泌過程に与える影響
- Author(s)
  青柳東代、相崎英樹、藤本陽、松本喜弘、松田麻未、Su Su Hmwe、渡邉則幸、渡士幸一、鈴木亮介、市野瀬志津子、松浦知和、鈴木哲朗、和氣健二郎、脇田隆字
- Organizer
  第24回抗ウイルス療法研究会総会
- Place of Presentation
  富士吉田
- Year and Date
  2014-05-07 – 2014-05-09
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Japanese encephalitis virus-subviral particles harboring HCV neutralization epitopes induce neutralizing antibodies against HCV.
- Author(s)
  Saga R, Fujimoto A, Watanabe N, Matsuda M, Suzuki R, Hasegawa M, Watashi K, Aizaki H, Nakamura N, Konishi E, Kato T, Takeyama H, Wakita T.
- Organizer
  21st International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] 培養系を用いた抗B型肝炎ウイルス化合物の同定と作用機序解析
- Author(s)
  渡士幸一、相崎英樹、脇田隆字
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] E1ペプチドによるHCV感染阻害機構の解析
- Author(s)
  渡邉則幸、伊達朋子、河野環、溝上雅史、相崎英樹、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] レチノイド阻害剤は NTCP 発現修飾を介して宿主細胞の B 型肝炎ウイルス感染感受性を消失させる
- Author(s)
  九十田千子、渡士幸一、岩本将士、鈴木亮介、相崎英樹、小嶋聡一、杉山真也、田中靖人、溝上雅史、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Aryl hydrocarbon receptor による脂肪滴形成及び C 型肝炎ウイルス粒子構築の制御
- Author(s)
  大橋啓史、渡士幸一、中嶋翔、金ソルイ、鈴木亮介、相崎英樹、紙透伸治、菅原二三男、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] 遺伝子組換え酵母由来 B 型肝炎ウイルス様粒子の細胞表面への結合に関与する宿主因子の解析
- Author(s)
  松田麻未、鈴木亮介、嵯峨涼平、藤本陽、渡士幸一、相崎英樹、森石恆司、岡本徹、松浦善治、黒田俊一、脇田隆字
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] NS5A-associated membrane protein, embryonic lethal, abnormal vision, drosophila-like 1, regulates hepatitis C virus RNA synthesis and translation.
- Author(s)
  Goto K, Fujimoto A, Watashi K, Suzuki R, Yamagoe S, Moriya K, Yotsuyanagi H, Koike K, Suzuki T, Wakita T, Aizaki H.
- Organizer
  21st International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Maintenance of HCV infectivity by down-regulating hepatic lipase expression.
- Author(s)
  Fujimoto A, Aizaki H, Matsuda M, Watanabe N, Watashi K, Suzuki R, Suzuki T, Wakita T.
- Organizer
  21st International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-24591001
[Presentation] Regulation of hepatitis C virus replication by liver X receptor is disrupted by a fungi-derived neoechinulin B.
- Author(s)
  Nakajima S, Watashi K, Kamisuki S, Takemoto K, Suzuki R, Aizaki H, Sugawara F, Wakita T.
- Organizer
  21st International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Banff (Canada)
- Year and Date
  2014-09-07 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-24591001

1. WAKITA Takaji (40280789)

# of Collaborated Projects: 5 results

# of Collaborated Products: 18 results
2. DATE Tomoko (40392360)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. MURAKAMI Kyoko (30399456)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. ISHII Koji (40280763)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. MORIKAWA Kenichi (60384377)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. HARADA Kentaro (30192701)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. SUZUKI Teturou (00250184)

# of Collaborated Projects: 2 results

# of Collaborated Products: 84 results
8. SUZUKI Ryosuke (50342902)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. KOJIMA SOICHI (10202061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. MIYAZAWA Keiji (40209896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MATSUMOTO Takehisa (20342652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MATSUURA Tomokazu (30199749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 溝上雅史 (40166038)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 森石恆司 (90260273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 葛西宏威 (20324189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MOGUSHI Kaoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. MASAKI Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. ITO Masahiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. YOSHII Kentaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 井本正哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. アリフセインハッサン

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 坪田昭人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 渡士幸一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 柊元巌

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 村松正道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 鈴木信弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 九十田千子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 近藤恭光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AIZAKI Hideki 相崎 英樹

Hideki Aizaki 相崎 英樹

相崎 英樹 アイザキ ヒデキ

Research Projects

Research Products

Co-Researchers

プラス鎖RNAウイルス複製に必要な膜小胞の形成メカニズムの解析Principal Investigator

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Study of the mechanism of PRC1-targeting genes in hepatitis C virus-infected liver

Principal Investigator

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Analysis of the mechanism of membrane vesicle formation required for the replication of hepatitis C virus and novel coronavirusPrincipal Investigator

Principal Investigator

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Analysis of the replication mechanism of hepatitis C virus in membrane vesicles containing replication complexesPrincipal Investigator

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Detection of host factors involved in active HCV replication complexPrincipal Investigator

Principal Investigator

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Studies on a role of TGF-beta mimetic activity of HCV NS3 protease in pathogenesis of liver cirrhosis

Principal Investigator

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C型肝炎ウイルスの感染増殖および粒子形成における脂質の役割

Principal Investigator

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Identification of molecular chaperones as regulators for HCV RNA replication through proteomics approachesPrincipal Investigator

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Analysis of the role of lipid in viral life cycles

Principal Investigator

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Research Institution

C型肝炎ウイルス複製に関与する宿主因子の同定とウイルス複製機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

C型肝炎ウイルスの感染初期過程に関与する宿主因子の探索

Principal Investigator

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Research Institution

感染性C型肝炎ウイルス粒子による肝細胞への遺伝子デリバリーシステムの構築

Principal Investigator

Project Period (FY)

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Research Institution

Analysis of factors involved in viral replication efficiency and search for novel anti -virals using HCV culture systems.

Principal Investigator

AIZAKI Hideki 相崎英樹

Hideki Aizaki 相崎英樹

相崎英樹アイザキヒデキ