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HONDA Koubun  本田 康文

ORCIDConnect your ORCID iD *help
Researcher Number 00335663
Other IDs
Affiliation (based on the past Project Information) *help 2007: 広島大, 医歯(薬)学総合研究科, 助手
2005 – 2006: 広島大学, 大学院医歯薬学総合研究科, 助手
2003 – 2005: 広島大学, 大学院・医歯薬学総合研究科, 助手
Review Section/Research Field
Principal Investigator
Orthodontic/Pediatric dentistry
Except Principal Investigator
Orthodontic/Pediatric dentistry
Keywords
Principal Investigator
PER2 / PER1 / 時計遺伝子 / 機械的負荷 / 滑膜細胞 / 軟骨細胞 / 歯根膜細胞 / 矯正力 / CD抗原 / 細胞増殖 … More / 細胞分化 / 再生 / 骨 / 軟骨 / 間葉系幹細胞 / 臍帯血 … More
Except Principal Investigator
ヒアルロニダーゼ / ヒアルロン酸 / SZP / Hyaluronidase / RGD-CAP / siRNA / HAoligo / Mechanical stress / Hyaluronic acid / mandibular condyle / 機械的負荷 / 下顎頭軟骨下骨 / 下顎頭表層 / 下顎頭軟骨 / Hyaluronan / Regeneration / PDL / MSC / 歯根膜細胞 / 歯根膜 / 再生 / 葉根膜 / 未分化間葉系幹細胞 / chondrocyte / hyaluronidase / mechanical stress / synovial membrane cell / low molecular hyaluronan (HA) / osteoarthritis / TIMP / MMP / 抗CD44抗体 / CD44 / ITI / TSG-6 / 機械的伸長力 / 軟骨細胞 / 機械的伸張力 / 滑膜細胞 / 低分子ヒアルロン酸 / 変形性顎関節症 / 細胞分化 / コラーゲン / 再生治療 / コラーゲンゲル / 軟骨 / 三次元培養 / 未分化間葉系細胞 Less
  • Research Projects

    (7 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (6 People)
  •  滑液性状が顎関節組織の基質代謝に及ぼす影響Principal Investigator

    • Principal Investigator
      本田 康文
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Hiroshima University
  •  Elucidation of condylar cartilage resorption mechanism in TMJ-osteoarthritis and search of a new regulatory factor

    • Principal Investigator
      TANNE Kazuo
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Hiroshima University
  •  矯正力が負荷された組織の分子リズムについてPrincipal Investigator

    • Principal Investigator
      本田 康文
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Hiroshima University
  •  未分化間葉系幹細胞を用いた下顎頭軟骨組織再生療法の開発

    • Principal Investigator
      土井 健義
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Hiroshima University
  •  臍帯血由来幹細胞による軟骨および骨組織再生Principal Investigator

    • Principal Investigator
      本田 康文
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Hiroshima University
  •  Establishment of treatment systematization aimed at inhibition of mandibular condyle resorption in osteoarthritis

    • Principal Investigator
      TANNE Kazuo
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Establishment of the periodontal ligament regeneration with mesenchymal stem cells

    • Principal Investigator
      TANIMOTO Kotaro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontic/Pediatric dentistry
    • Research Institution
      Hiroshima University

All 2008 2006 2005 2004

All Journal Article Presentation

  • [Journal Article] The effect of mechanical loading on the metabolism of growth plate chondrocyte2008

    • Author(s)
      Ueki M, Tanaka N, Tanimoto K, Nishio C, Honda K, Lin YY, Tanne Y, Ohkuma S, Kamiya T, Tanaka E, Tanne K.
    • Journal Title

      Annals of biomedical engineering 36

      Pages: 793-800

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Journal Article] The effect of mechanical loading on the metabolism of growth plate chondrocytes2008

    • Author(s)
      Ueki, M., Tanaka, N., Tanimoto, K., Nishio, C., Honda, K., Lin, YY., Tanne, Y., Ohkuma, S., Kamiya, T., Tanaka, E., Tanne, K
    • Journal Title

      Ann Biomed Eng 36

      Pages: 793-800

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Journal Article] The effect of mechanical loading on the metabolism of growth plate chondrocyte2008

    • Author(s)
      Ueki M, Tanaka N, Tanimoto K, Nishio C, Honda K, Lin YY, Tanne Y, Ohkuma S, Kamiya T, Tanaka E, Tanne K.
    • Journal Title

      Annals of biomedical engineering (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Journal Article] Expression of superficial zone protein in mandibular condyle cartilage2006

    • Author(s)
      Ohno, S., Schmid, T., Tanne, Y., Kamiya, T., Honda, K., Ohno-Nakahara, M., Swentko, N., Desai, T., Tanne, K., Knudson, C., Knudson, W
    • Journal Title

      Osteoarthritis Cartilage 14

      Pages: 807-813

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Journal Article] Expression of superficial zone protein in mandibular condyle-cartilage2006

    • Author(s)
      Ohno S, Schmid T, Tanne Y, Kamiya T, Honda K, Ohno-Nakahara M, Swentko N, Desai TA, Tanne K, Knudson CB, Knudson W.
    • Journal Title

      Osteoarthritis Cartilage 14

      Pages: 807-813

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Journal Article] The metabolism of hyaluronan in cultured rabbit growth plate chondrocytes during differentiation.2005

    • Author(s)
      Suzuki A, Tanimoto K, Ohno S, Nakatani Y, Honda K, Tanaka N, Doi T, Ohno-Nakahara M, Yoneno K, Ueki M, Tanne K
    • Journal Title

      Biochim Biophys Acta 1743・(1-2)

      Pages: 57-63

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Multidifferentiation potential of mesenchymal stem cells in three-dimensional collagen gel cultures2005

    • Author(s)
      Yoneno K, Ohno S, Tanimoto K, Honda K, Tanaka N, Doi T, Kawata T, Tanaka E, Kapila S, Tanne K.
    • Journal Title

      J Biomed Mater Res A 75・(3)

      Pages: 733-741

    • NAID

      120006665102

    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Cyclic mechanical strain regulates the PTHrP expression in cultured chondrocytes via activation of the Ca2+ channel2005

    • Author(s)
      Tanaka N, Ohno S, Honda K, Tanimoto K, et al.
    • Journal Title

      J Dent Res 84(1)

      Pages: 64-68

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15592165
  • [Journal Article] Cyclic mechanical strain regulates the PTHrP expression in cultured chondrocytes via activation of the Ca2+ channel.2005

    • Author(s)
      Tanaka N, Ohno S, Honda K, Tanimoto K, Doi T, Ohno-Nakahara M, Tafolla E, Kapila S, Tanne K
    • Journal Title

      Journal of Dental Research 84

      Pages: 64-68

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Mechanical Regulation of Terminal Chondrocyte Differentiation via RGD-CAP/beta ig-h3 Induced by TGF-beta2005

    • Author(s)
      Ohno S, Tanaka N, Ueki M, Honda K, Tanimoto K, Yoneno K, Ohno-Nakahara M, Fujimoto K, Kato Y, Tanne K.
    • Journal Title

      Connect Tissue Res. 46・(4-5)

      Pages: 227-234

    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] The metabolism of hyaluronan in cultured rabbit growth plate chondrocytes during differentiation.2005

    • Author(s)
      Suzuki A, Tanimoto K, Ohno S, Nakatani Y, Honda K, Tanaka N, Doi T, Ohno-Nakahara M, Yoneno K, Ueki M, Tanne K
    • Journal Title

      Biochim Biophys Acta 1743

      Pages: 57-63

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Cyclic mechanical strain regulates the PTHrP expression in cultured chondrocytes via activation of the Ca2+ channel.2005

    • Author(s)
      Tanaka N, Ohno S, Honda K, Tanimoto K, Doi T, Ohno-Nakahara M, Tafolla E, Kapila S, Tanne K.
    • Journal Title

      Journal of Dental Research 84・(1)

      Pages: 64-68

    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Cyclic mechanical strain regulates the PTHrP expression in cultured chondrocytes via activation of the Ca2+ channel2005

    • Author(s)
      Tanaka N, Ohno S, Honda K, Tanimoto K, et al.
    • Journal Title

      J Dent Res. 84(1)

      Pages: 64-68

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15592165
  • [Journal Article] The metabolism of hyaluronan in cultured rabbit growth plate chondrocytes during differentiation.2005

    • Author(s)
      Suzuki A, Tanimoto K, Ohno S, Nakatani Y, Honda K, Tanaka N, Doi T, Ohno-Nakahara M, Yoneno K, Ueki M, Tanne K.
    • Journal Title

      Biochim Biophys Acta 1743・(1-2)

      Pages: 57-63

    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Cyclic mechanical strain regulates the PTHrP expression in cultured chondrocytes via activation of the Ca2+ channel.2005

    • Author(s)
      Tanaka N, Ohno S, Honda K, Tanimoto K, Doi T, Ohno-Nakahara M, Tafolla E, Kapila S, Tanne K
    • Journal Title

      Journal of Dental Research 84・(1)

      Pages: 64-68

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Induction of CD44 and MMP Expression by Hyaluronidase Treatment of Articular Chondrocytes2004

    • Author(s)
      Ohno-Nakahara M, Honda K, Tanimoto K, et al.
    • Journal Title

      J Biochem (Tokyo) 135(5)

      Pages: 567-575

    • NAID

      10016199715

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15592165
  • [Journal Article] Induction of CD44 and MMP expression by hyaluronidase treatment of articular chondrocytes2004

    • Author(s)
      Ohno-Nakahara M, Honda K, Tanimoto K, Tanaka N, Doi T, Suzuki A, Yoneno K, Nakatani Y, Ueki M, Ohno S, Knudson W, Knudson CB, Tanne K.
    • Journal Title

      Journal of Biochemistry 135・(5)

      Pages: 567-575

    • NAID

      10016199715

    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Hyaluronidase ecpression in cultured growth plate chondrocytes during differentiation2004

    • Author(s)
      Tanimoto K, Suzuki A, Ohno S, Honda K, Tanaka N, Doi T, Nakahara-ohno M, Yoneno K, Nakatani Y, Ueki M, Yanagida T, Kitamura R, Tanne K
    • Journal Title

      Cell and Tissue Research 318・(2)

      Pages: 335-342

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Effects of TGF-beta on hyaluronan anabolism in fibroblasts derived from the synovial membrane of the rabbit temporomandibular joint.2004

    • Author(s)
      Tanimoto K, Suzuki A, Ohno S, Honda K, Tanaka N, Doi T, Yoneno K, Ohno-Nakahara M, Nakatani Y, Ueki M, Tanne K.
    • Journal Title

      Journal of Dental Research 83・(1)

      Pages: 40-44

    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Utility of urinary pyridinoline and deoxypyridinoline ratio for diagnosis of osteoarthritis at temporomandibular joint.2004

    • Author(s)
      Tanimoto K, Ohno S, Imada M, Honda K, Ohno-Nakahara M, Kapila S, Tanne K
    • Journal Title

      J Oral Pathol Med. 33

      Pages: 218-223

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Induction of CD44 and MMP expression by hyaluronidase treatment of articular chondrocytes2004

    • Author(s)
      Nakatani Y, Ohno-Nakahara M, Honda K, Tanimoto K, Tanaka N, Doi T, Suzuki A, Nakatani Y, Ueki M, Ohno S, Knudson W,, Knudson CB, Tanne K
    • Journal Title

      Journal of Biochemistry 135・(5)

      Pages: 567-575

    • NAID

      10016199715

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Effects of TGF-beta on hyaluronan anabolism in fibroblasts derived from the synovial membrane of the rabbit temporomandibular joint.2004

    • Author(s)
      Tanimoto K, Suzuki A, Ohno S, Honda K, Tanaka N, Doi T, Yoneno K, Ohno-Nakahara M, Nakatani Y, Ueki M, Tanne K
    • Journal Title

      Journal of Dental Research 83・(1)

      Pages: 40-44

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Hyaluronidase expression in cultured growth plate chondrocytes during differentiation.2004

    • Author(s)
      Tanimoto K, Suzuki A, Ohno S, Honda K, Tanaka N, Doi T, Nakahara-Ohno M, Yoneno K, Nakatani Y, Ueki M, Yanagida T, Kitamura R, Tanne K.
    • Journal Title

      Cell and Tissue Research 318・(2)

      Pages: 335-342

    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Induction of CD44 and MMP expression by hyaluronidase treatment of articular chondrocytes2004

    • Author(s)
      Ohno-Nakahara M, Honda K, Tanimoto K, Tanaka N, Doi T, Suzuki A, Yoneno K, Nakatani Y, Ueki M, Ohno S, Knudson W, Knudson CB, Tanne K
    • Journal Title

      Journal of Biochemistry 135

      Pages: 567-575

    • NAID

      10016199715

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Effects of TGF-beta on hyaluronan anabolism in fibroblasts derived from the synovial membrane of the rabbit temporomandibular joint.2004

    • Author(s)
      Tanimoto K, Suzuki A, Ohno S, Honda K, Tanaka N, Doi T, Yoneno K, Ohno-Nakahara M, Nakatani Y. Ueki M, Tanne K
    • Journal Title

      Journal of Dental Research 83

      Pages: 40-44

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Hyaluronidase expression in cultured growth plate chondrocytes during differentiation.2004

    • Author(s)
      Tanimoto K, Suzuki A, Ohno S, Honda K, Tanaka N, Doi T, Nakahara-Ohno M, Yoneno K, Nakatani Y, Ueki M, Yanagida T, Kitamura R, Tanne K
    • Journal Title

      Cell and Tissue Research 318

      Pages: 335-342

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390636
  • [Journal Article] Induction of CD44 and MMP Expression by Hyaluronidase Treatment of Articular Chondrocytes2004

    • Author(s)
      Ohno-Nakahara M, Honda K, Tanimoto K, et al.
    • Journal Title

      J Biochem (Tokyo). 135(5)

      Pages: 567-575

    • NAID

      10016199715

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15592165
  • [Presentation] 軟骨細胞の分化過程におけるRunx2活性に対するヒアルロン酸の影響2006

    • Author(s)
      丹根 由起、本田 康文、谷本 幸太郎、田中 伸明、米野 潔、植木 雅士、中谷 有希、北村 玲子、柳田 珠美、林 于郁、大熊 暁、神谷 貴志、丹根 一夫
    • Organizer
      第65回日本矯正歯科学会大会
    • Place of Presentation
      札幌市
    • Year and Date
      2006-09-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Presentation] Effects of fluid flow stress and hyaluronic acid on SZP expression in cultured TMJ chondrocytes2006

    • Author(s)
      Kamiya T., Honda K., Lin Y.Y., Tanne K.
    • Organizer
      第19回中華民國歯顎矯正學會
    • Place of Presentation
      Taipei
    • Year and Date
      2006-12-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Presentation] Influences of hyaluronan on the activation of Runt, during chondrocyte differentiation2006

    • Author(s)
      Ueki, M., Tanaka, N., Honda, K., Lin, Y.Y., Nakatani, Y., Kitamura, R., Yanagida, T., Tanne, Y., Ohkuma, S., Kamiya, T., Tanne, K
    • Organizer
      The 65th Annual Meeting of the Japanese Orthodontic Society
    • Place of Presentation
      Sapporo
    • Year and Date
      2006-09-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Presentation] Effects of mechanical stimuli on the proliferation and differentiation of growth plate chondrocytes from different-aged hosts2006

    • Author(s)
      Ueki, M., Tanaka, N., Honda, K., Lin, Y.Y., Nakatani, Y., Kitamura, R., Yanagida, T., Tanne, Y., Ohkuma, S., Kamiya T., Tanne, K
    • Organizer
      The 65th Annual Meeting of the Japanese Orthodontic Society
    • Place of Presentation
      Sapporo
    • Year and Date
      2006-09-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Presentation] Effects of fluid flow stress and hyaluronic acid on SZP expression in cultured TMJ chondrocytes2006

    • Author(s)
      Kamiya, T., Honda, K., Lin, Y.Y., Tanne, K
    • Organizer
      The 19th Taiwan Association of Orthodontics
    • Place of Presentation
      Taipei
    • Year and Date
      2006-12-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Presentation] Runx2 activation by hyaluronan during chondrocyte differentiation2006

    • Author(s)
      Tanne Y., Ohno S., Honda K., Tanimoto K., Tanaka N., Ohno-Nakahara M., Yoneno K., Ueki M., Nakatani Y., Kitamura R., Yanagida T., Lin Y.Y., Ohkuma S., Kamiya T., Tanne K.
    • Organizer
      84th General Session & Exhibition of the IADR
    • Place of Presentation
      Brisbane
    • Year and Date
      2006-06-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Presentation] 滑膜性関節における潤滑物質代謝に対する化学的媒介物質および機械的負荷の影響2006

    • Author(s)
      柳田 珠美、本田 康文、谷本 幸太郎、田中 伸明、米野 潔、植木 雅士、中谷 有希、北村 玲子、丹根 由起、大熊 暁、神谷 貴志、丹根 一夫
    • Organizer
      第65回日本矯正歯科学会大会
    • Place of Presentation
      札幌市
    • Year and Date
      2006-09-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Presentation] 宿主年齢の異なる成長板軟骨細胞の増殖および分化に及ぼす機械的刺激の影響2006

    • Author(s)
      植木 雅士、田中 伸明、本田 康文、林 于郁、中谷 有希、北村 玲子、柳田 珠美、丹根 由起、大熊 暁、神谷 貴志、丹根 一夫
    • Organizer
      第65回日本矯正歯科学会大会
    • Place of Presentation
      札幌市
    • Year and Date
      2006-09-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390554
  • [Presentation] Influences of chemical mediators and mechanical stress in synovial joint on lubricant metabolism2006

    • Author(s)
      Yanagida, Y., Honda, K., Tanimoto, K., Tanaka, N., Yoneno, K., Ueki, M., Nakatani, Y., Kitamura, R., Tanne, Y., Ohkuma, S., Kamiya, T., Tanne, K
    • Organizer
      The 65th Annual Meeting of the Japanese Orthodontic Society
    • Place of Presentation
      Sapporo
    • Year and Date
      2006-09-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390554
  • 1.  TANIMOTO Kotaro (20322240)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 29 results
  • 2.  TANNE Kazuo (30159032)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 32 results
  • 3.  OHNO Shigeru (30304447)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 18 results
  • 4.  TANAKA Nobuaki (90397969)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 5.  土井 健義 (10363087)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  佐々木 彰子 (00325177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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