ASADA AKIKO 浅田明子

… Alternative Names

浅田明子アサダアキコ

ASADA Akiko 浅田明子

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Researcher Number	00336512
Other IDs
Affiliation (Current)	2025: 東京都立大学, 理学研究科, 助教
Affiliation (based on the past Project Information) *help	2015: 首都大学東京, 大学院理工学研究科, 助教 2007 – 2010: 首都大学東京, 大学院・理工学研究科, 助教 2007: Tbkyo Metropolitan University, Graduate School of Secience and Engineering, Assistant Professor 2006: 首都大学東京, 大学院理工学研究科, 助手 2005: 首都大学東京, 都市教養学部, 助手
Review Section/Research Field	Except Principal Investigator Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Functional biochemistry
Keywords	Except Principal Investigator Cdk5 / タンパク質 / 酵素 / リン酸化 / 老化 / Grab / GRAB / Rab / LMTK1 / 発生・分化 … More / 神経科学 / Sienal transduction / Calo ain / Proteasome / Alzheimer / Neuron / Protein kinase / Phosohorvlation / 細胞膜 / 蛋白質 / アルツハイマー / 細包膜 / 分解 / シグナル伝達 / 脳・神経 / AATYK1 / 神経細胞 / AAYK1 / リサイクリング / エンドサイトーシス / エンドソーム / AATYK / CIN85 Less

Physiology and pathology of endocytosis and recycling transport in neurons
- Principal Investigator
  
  Hisanaga Shin-ichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Metropolitan University
Regulation of endosome formation and recycling by Cdk5/p35 in neurons
- Principal Investigator
  
  HISANAGA Shin-ichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan University
Regulation of Cdk5 activity and function in neurons
- Principal Investigator
  
  HISANAGA Shin-ichi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Metropolitan University

All 2015 2014 2013 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Cyclin-dependent kinase 5 phosphorylates and induces the degradation of ataxin-22014
- Author(s)
  Asada, A., Yamazaki, R., Kino, Y., Saito, T., Kimura, T., Miyake, M., Hasegawa, M., Nukina, N. & Hisanaga, S.
- Journal Title
  
  Neurosci. Lett.
  
  Volume: 563 Pages: 112-117
- DOI
  10.1016/j.neulet.2014.01.046
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22110004, KAKENHI-PROJECT-23791007, KAKENHI-PROJECT-24659436, KAKENHI-PROJECT-25290024, KAKENHI-PROJECT-25461299, KAKENHI-PLANNED-26117005
[Journal Article] Quantitative Measurement of In Vivo Phosphorylation States of Cdk5 Activator p35 by Phos-tag SDS-PAGE.2010
- Author(s)
  Hosokawa T., Saito, T., Asada, A., Fukunaga, K., Hisanaga S.
- Journal Title
  
  Mol.Cell.Proteomics. 9
  
  Pages: 1133-1143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370047
[Journal Article] AATYK1A phosphorylation by Cdk5 regulates the recycling endosome pathway.2010
- Author(s)
  Takano, T., Tsutsumi, K., Saito, T., Asada, A., Tomomura, M., Fukuda, M., Hisanaga S.
- Journal Title
  
  Genes Cells 15
  
  Pages: 783-797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370047
[Journal Article] Membrane association facilitates degradation and cleavage of the cyclin-dependent kinase 5 activators p35 and p39.2010
- Author(s)
  Minegishi, S., Asada, A., Miyauchi, S., Fuchigami, T., Saito, T., Hisanaga, S.
- Journal Title
  
  Biochemistry 49
  
  Pages: 5482-5493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370047
[Journal Article] Neuronal expression of two isoforms of mouse Septin 5.2010
- Author(s)
  Asada, A., Takahashi, J., Taniguchi, M., Yamamoto, H., Kimura, T., Saito, T., Hisanaga S.
- Journal Title
  
  J.Neurosci.Res. 88
  
  Pages: 1309-1316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370047
[Journal Article] Commitment of MPP+-induced neuronal cell death by proteasome-mediated degradation of p35 Cdk5 activator.2009
- Author(s)
  Endo, R., Saito, T.,Asada, A., Kawahara, H., Ohshima, T., Hisanaga S.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 26029-26039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370047
[Journal Article] Effect of pin1 or microtubule binding on dephosphorylation of FTDP-17 mutant tau.2009
- Author(s)
  Yotsumoto, K., Saito, T., Asada, A., Oikawa, T., Kimura, T., Uchida, C., Ishiguro, K., Uchida, T., Hasegawa, M., Hisanaga S.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 16840-16847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370047
[Journal Article] Suppression of mutant huntingtin aggregate formation by Cdk5/p35 through the effect on microtubule stability.2008
- Author(s)
  Kaminosono, S., Saito, T., Oyama, F., Ohshima, T., Asada, A., Nagai, Y., Nukina, N., Hisanaga S.
- Journal Title
  
  J.Neurosci. 28
  
  Pages: 8747-8755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370047
[Journal Article] Myristoylation of p39 and p35 is a determinant of cytoplasmic or nuclear localization of active cycline-dependent kinase 5 (Cdk5) complexes.2008
- Author(s)
  Asada, A., Yamamoto, N., Gohda, M., Saito, T., Hayashi, N., Hisanaga S.
- Journal Title
  
  J.Neurochem. 106
  
  Pages: 1325-1336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370047
[Journal Article] Myristoylation of p39 and p35 is a determinant of cytoplasmic or nuclear localization of active cycline-dependent kinase 5 (Cdk5)complexes.2008
- Author(s)
  Asada, et al.
- Journal Title
  
  J. Neurochem. 106
  
  Pages: 1325-1336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370047
[Journal Article] Calpastatin, an endogenous calpain-inhibitor protein, regulates the cleavage of the Cdk5 activator p35 to p25.
- Author(s)
  Sato, K., Minegishi, S., Takano, J., Plattner, F., Saito, T., Asada, A., Kawahara, H., Iwata, N., Saido, T.C., Hisanaga S.
- Journal Title
  
  J. Neurochem. In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370047
[Presentation] GRAB, a GEF of Rab8, regulates axonal outgrowth in a Cdk5 phosphorylation-dependent manner.2015
- Author(s)
  Furusawa, K., Asada, A., Fukuda, M., Hisanaga, S.
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  さいたま市、大宮ソニックシティー
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25290024
[Presentation] 脊髄小脳変性症２型原因タンパク質 Ataxin- 2 の Cdk5 によるリン酸化2013
- Author(s)
  浅田明子他
- Organizer
  第５6回日本神経化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25290024
[Presentation] p35/Cdk5とp39/Cdk5の細胞内局在に及ぼすCdk5キナーゼ活性の影響2010
- Author(s)
  浅田明子
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20370047
[Presentation] p35/Cdk5とp39/Cdk5の細胞内局在に及ぼすCdk5キナーゼ活性の影響2008
- Author(s)
  浅田明子
- Organizer
  第31回日本分子生物学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20370047
[Presentation] 前頭側頭葉認知症(FTDP-17)変異型タウの脱リン酸化2008
- Author(s)
  浅田明子
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20370047

1. HISANAGA Shin-ichi (20181092)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
2. SAITO Taro (70301413)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 貫名信行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ASADA AKIKO 浅田 明子

浅田 明子 アサダ アキコ

ASADA Akiko 浅田 明子

Research Projects

Research Products

Co-Researchers

Physiology and pathology of endocytosis and recycling transport in neurons

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of endosome formation and recycling by Cdk5/p35 in neurons

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of Cdk5 activity and function in neurons

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cyclin-dependent kinase 5 phosphorylates and induces the degradation of ataxin-22014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quantitative Measurement of In Vivo Phosphorylation States of Cdk5 Activator p35 by Phos-tag SDS-PAGE.2010

Author(s)

Journal Title

Data Source

[Journal Article] AATYK1A phosphorylation by Cdk5 regulates the recycling endosome pathway.2010

Author(s)

Journal Title

Data Source

[Journal Article] Membrane association facilitates degradation and cleavage of the cyclin-dependent kinase 5 activators p35 and p39.2010

Author(s)

Journal Title

Data Source

[Journal Article] Neuronal expression of two isoforms of mouse Septin 5.2010

Author(s)

Journal Title

Data Source

[Journal Article] Commitment of MPP+-induced neuronal cell death by proteasome-mediated degradation of p35 Cdk5 activator.2009

Author(s)

Journal Title

Data Source

[Journal Article] Effect of pin1 or microtubule binding on dephosphorylation of FTDP-17 mutant tau.2009

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of mutant huntingtin aggregate formation by Cdk5/p35 through the effect on microtubule stability.2008

Author(s)

Journal Title

Data Source

[Journal Article] Myristoylation of p39 and p35 is a determinant of cytoplasmic or nuclear localization of active cycline-dependent kinase 5 (Cdk5) complexes.2008

Author(s)

Journal Title

Data Source

[Journal Article] Myristoylation of p39 and p35 is a determinant of cytoplasmic or nuclear localization of active cycline-dependent kinase 5 (Cdk5)complexes.2008

Author(s)

Journal Title

Data Source

[Journal Article] Calpastatin, an endogenous calpain-inhibitor protein, regulates the cleavage of the Cdk5 activator p35 to p25.

Author(s)

Journal Title

Data Source

[Presentation] GRAB, a GEF of Rab8, regulates axonal outgrowth in a Cdk5 phosphorylation-dependent manner.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 脊髄小脳変性症２型原因タンパク質 Ataxin- 2 の Cdk5 によるリン酸化2013

Author(s)

Organizer

Place of Presentation

Data Source

ASADA AKIKO 浅田明子

浅田明子アサダアキコ

ASADA Akiko 浅田明子