SO Tomoko 宗知子

Researcher Number	00341529
Affiliation (based on the past Project Information) *help	2014 – 2015: 産業医科大学, 医学部, 講師 2012 – 2013: 産業医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Respiratory surgery Except Principal Investigator Thoracic surgery / Respiratory surgery
Keywords	Principal Investigator 悪性胸膜中皮腫 / 上皮間葉系移行(EMT) / 細胞分離用磁性粒子 / 細胞分離 / EpCAM / 循環腫瘍細胞 / 肺癌 Except Principal Investigator 循環腫瘍細胞 / 診断 / バイオマーカー … More / 耐性 / EGFR-TKI / EML4-ALK / lung cancer / 循環血液中腫瘍細胞 / CellSearch / 循環腫瘍細胞（CTC） / 上皮接着分子(EpCAM) / CTC-chip / 循環腫瘍細胞(CTC) / 肺癌 / 予後 / 血液 / 胸膜中皮腫 / CTC / 中皮腫 / 循環内皮細胞 / 悪性胸膜中皮腫 Less

Development of a sensitive system for capturing circulating tumor cells in lung cancer.Principal Investigator
- Principal Investigator
  
  SO Tomoko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
Analysis of molecular mechanism forEML4-ALK/ EGFR-TKI resistance and establishment of less invasive diagnosis.
- Principal Investigator
  
  URAMOTO Hidetaka
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
Blood biomarker in malignant pleural mesothelioma
- Principal Investigator
  
  TANAKA Fumihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
Development of high sensitivity detection method of CTCs in lung cancer using microfluidic chip system
- Principal Investigator
  
  OKA Soichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2016 2015 2013 2012 Other

All Journal Article Presentation

[Journal Article] ZEB1 Mediates Acquired Resistance to the Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer.2016
- Author(s)
  Yoshida T, Song L, Bai Y, Kinose F, Li J, Ohaegbulam KC, Munoz-Antonia T, Qu X, Eschrich S, Uramoto H, Tanaka F, Nasarre P, Gemmill RM, Roche J, Drabkin HA, Haura EB.
- Journal Title
  
  PLoS One
  
  Volume: 11(1) Issue: 1 Pages: e0147344-e0147344
- DOI
  10.1371/journal.pone.0147344
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462190, KAKENHI-PROJECT-25462202
[Journal Article] rognostic impact of clinical variables on surgically resected small-cell lung cancer: Results of a retrospective multicenter analysis (FIGHT002A and HOT1301A)2015
- Author(s)
  Yokouchi H, Ishida T, Yamazaki S, Kikuchi H, Oizumi S, Uramoto H, Tanaka F, Harada M, Akie K, Sugaya F, Fujita Y, Fukuhara T, Takamura K, Kojima T, Harada T, Higuchi M, Matsuura Y, Honjo O, Minami Y, Watanabe N, Nishihara H, Suzuki H, Dosaka-Akita H, Isobe H, Nishimura M, Munakata M
- Journal Title
  
  Lung Cancer
  
  Volume: 90 Issue: 3 Pages: 548-53
- DOI
  10.1016/j.lungcan.2015.10.010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09164, KAKENHI-PROJECT-25462182, KAKENHI-PROJECT-25462190, KAKENHI-PROJECT-25462202
[Journal Article] Erlotinib resistance in lung cancer cells mediated by integrinβ1/Src/Akt-driven bypass signaling2013
- Author(s)
  Kanda R, Kawahara A, Watari K, Murakami Y, Sonoda K, Maeda M, Fujita H, Kage M, Uramoto H, Costa C, Kuwano M, Ono M(12人中9番目）
- Journal Title
  
  Cancer Res
  
  Volume: 73 Pages: 6243-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462202
[Journal Article] Prognostic implications of human leukocyte antigen class I expression in patients who underwent surgical resection for non-small cell lung cancer.2013
- Author(s)
  Hanagiri T, Shigematsu Y, Kuroda K, Baba T, Shiota H, Ichiki Y, Nagata Y, Yasuda M, Uramoto H, So T, Takenoyama M, Tanaka F.
- Journal Title
  
  J Surg Res
  
  Volume: 181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390335
[Journal Article] Intrapleural chemotherapy improves the survival of non-small cell lung cancer patients with positive pleural lavage cytology.2013
- Author(s)
  Baba T, Uramoto H, Kuwata T, Takenoyama M, Chikaishi Y, Oka S, Nagata Y, Shigematsu Y, Shimokawa H, Nakagawa M, So T, Hanagiri T, Tanaka F.
- Journal Title
  
  Surg Today
  
  Volume: 43 Issue: 6 Pages: 648-53
- DOI
  10.1007/s00595-012-0281-y
- NAID
  10031176087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390335, KAKENHI-PROJECT-25462190, KAKENHI-PROJECT-25462192, KAKENHI-PROJECT-25462202
[Journal Article] Discriminative features of thin-slice CT for peripheral intrapulmonary lymph nodes.2013
- Author(s)
  Takenaka M, Uramoto H, Shimokawa H, So T, Hanagiri T, Aoki T, Tanaka F.
- Journal Title
  
  Asian J Surg
  
  Volume: 36 Issue: 2 Pages: 69-73
- DOI
  10.1016/j.asjsur.2012.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390335, KAKENHI-PROJECT-25462190, KAKENHI-PROJECT-25462192, KAKENHI-PROJECT-25462202
[Journal Article] Prognostic implications of human leukocyte antigen class I expression in patients who underwent surgical resection for non-small-cell lung cancer2013
- Author(s)
  Hanagiri T, Shigematsu Y, Kuroda K, Baba T, Shiota H, Ichiki Y, Nagata Y, Yasuda M, Uramoto H, So T, Takenoyama M, Tanaka F（12人中9番目）
- Journal Title
  
  J Surg Res
  
  Volume: 181 Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462202
[Journal Article] Clinical Significance of Expression of　Cancer/testis Antigen and Down-regulation of HLA Class-I in Patients with Stage I　Non-small Cell Lung Cancer2013
- Author(s)
  Hanagiri T, Shigematsu Y, Shinohara S, Takenaka M, Oka S, Chikaishi Y, Nagata Y, Baba T, Uramoto H, So T, Yamada S（11人中9番目）
- Journal Title
  
  Anticancer Res
  
  Volume: 33 Pages: 2123-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462202
[Journal Article] Serum Level of Osteopontin as a Prognostic Factor in Patients Who Underwent Surgical Resection for Non-Small-Cell Lung Cancer2013
- Author(s)
  Takenaka M, Hanagiri T, Shinohara S, Yasuda M, Chikaishi Y, Oka S, Shimokawa H, Nagata Y, Nakagawa M, Uramoto H, So T, Yamada S, Tanaka F（13人中10番目）
- Journal Title
  
  Clin Lung Cancer
  
  Volume: 14 Issue: 3 Pages: 288-94
- DOI
  10.1016/j.cllc.2012.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462190, KAKENHI-PROJECT-25462192, KAKENHI-PROJECT-25462202
[Journal Article] Clinical significance of the frequency of regulatory T cells in regional lymph node lymphocytes as a prognostic factor for non-small-cell lung cancer.2013
- Author(s)
  Hanagiri T, Shigematsu Y, Shimokawa S, Takenaka M, Oka S, Chikaishi Y, Nagata Y, Iwata T, Uramoto H, So T, Tanaka F.
- Journal Title
  
  Lung Cancer
  
  Volume: 81 Pages: 475-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390335
[Presentation] Capture of EpCAM-negative circulating tumor cells (CTCs) with a “Universal CTC-Chip”.2015
- Author(s)
  Kazue Yoneda, Yasuhiro Chikaishi, Eri Kawashima, Tomoko So, Hidetaka Uramoto, Takashi Ohnaga, Fumihiro Tanaka.
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Philadelphia（USA)
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462191
[Presentation] Capture of EpCAM-negative circulating tumor cells (CTCs) with a “Universal CTC-Chip”2015
- Author(s)
  Yoneda K, Chikaishi Y, Kawashima E, So T, Uramoto H, Ohnaga T, Tanaka F
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462202
[Presentation] EML4-ALK、及びEGFR-TKIに対する耐性関連分子MED12に基づく新しい肺癌治療の戦略2013
- Author(s)
  浦本秀隆、平良彰浩、竹中　賢、近石泰弘、岡壮一、下川秀彦、宗知子、花桐武志、田中文啓
- Organizer
  第52回日本肺癌学会総会
- Place of Presentation
  ホテルニューオータニ東京
- Data Source
  KAKENHI-PROJECT-25462202
[Presentation] Novel malignant-mesothelioma-associated antigens (Gene-X and THBS-2) in the diagnosis of malignant pleural mesothelioma (MPM)2013
- Author(s)
  Tanaka F, Shigematsu Y, Hanagiri T， Uramoto H, So T, Yoneda K, Takuwa T, Hashimoto M, Matsumoto S, Okumura Y, Kondo N, Hasegawa S
- Organizer
  49ｔｈ American Society of clinical oncology
- Place of Presentation
  Chicago,USA
- Data Source
  KAKENHI-PROJECT-25462202
[Presentation] Development of system to detect circulating tumor cell in malignant pleural mesothelioma2013
- Author(s)
  Yasuhiro Chikaishi, Tomoko So, Masaru Takenaka, Soichi Oka, Makoto Nakagawa, Hidehiko Shimokawa, Teruo Iwata, Hidetaka Uramoto, Takeshi Hanagiri, Fumihiro Tanaka, Takeshi Ohnaga
- Organizer
  AACR meeting
- Place of Presentation
  Washington,USA
- Data Source
  KAKENHI-PROJECT-24592108
[Presentation] Development of system to detect circulating tumor cell in malignant pleural mesothelioma2013
- Author(s)
  Yasuhiro Chikaishi, Tomoko So, Masaru Takenaka, Soichi Oka, Makoto Nakagawa, Hidehiko Shimokawa, Teruo Iwatav, Hidetaka Uramoto, Takeshi Hanagiri, Fumihiro Tanaka, Takeshi Ohnaga
- Organizer
  AACR meeting
- Place of Presentation
  Washington,USA
- Data Source
  KAKENHI-PROJECT-25462191
[Presentation] 循環腫瘍細胞（CTC）の検出方法の開発2013
- Author(s)
  近石泰弘、宗　知子、米田和恵、浦本秀隆、花桐武志
- Organizer
  BioJapan2013
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24592108
[Presentation] 循環腫瘍細胞（CTC）の検出方法の開発2013
- Author(s)
  近石泰弘、宗　知子、米田和恵、浦本秀隆、花桐武志、大永　崇、田中文啓
- Organizer
  BioJapan2013
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25462191
[Presentation] Development of detecting systems for circulating tumor cells in malignant pleural mesothelioma patients2013
- Author(s)
  Chikaishi Y, So T, Oka S, Takenaka M, Nakagawa M, Shimokawa H, Iwata T, Nagata Y, Uramoto H, Hanagiri T, Ohnaga T, Uramoto H, Tanaka F
- Organizer
  AACR (The American Association for Cancer Research) Meeting
- Place of Presentation
  Washington,USA
- Data Source
  KAKENHI-PROJECT-25462202
[Presentation] 心合併症を有する肺癌症例の周術期管理について2012
- Author(s)
  宗知子,田中文啓(14人中14番目)
- Organizer
  第53回日本肺癌学会総会
- Place of Presentation
  岡山コンベンションセンター(岡山)
- Data Source
  KAKENHI-PROJECT-24390335
[Presentation] 心脳血管合併症を有する患者の肺癌手術-周術期合併症について-2012
- Author(s)
  宗知子,田中文啓(13人中13番目)
- Organizer
  第29回日本呼吸器外科学会総会
- Place of Presentation
  秋田キャッスルホテル(秋田)
- Data Source
  KAKENHI-PROJECT-24390335
[Presentation] Comparison of CellSearch with polymeric microfluidic devices for CTC isolation using EpCAM-negative tumor cell lines of malignant pleural mesothelioma
- Author(s)
  Yasuhiro Chikaishi1), Tomoko So1), Masaru Takenaka1), Soichi Oka1), Ayako Hirai1), Takashi Iwanami1), Kazue Yoneda1), Hidehiko Shimokawa1), Yoshika Nagata1), Hidetaka Uramoto1), Takeshi Ohnaga2), and Fumihiro Tanaka1)
- Organizer
  AACR meeting
- Place of Presentation
  San Diego CA(USA)
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-24592108
[Presentation] Capture of EpCAM-negative circulating tumor cells (CTCs) with a “Universal CTC-Chip”
- Author(s)
  Kazue Yoneda , Yasuhiro Chikaishi , Rie Kawashima , Tomoko So, Hidetaka Uramoto , Takeshi Ohnaga, Fumihiro Tanaka
- Organizer
  AACR (American Society of Cancer Research) 2015 Annual Meeting
- Place of Presentation
  Philadelphia, PA, USA
- Year and Date
  2015-04-18 – 2015-04-22
- Data Source
  KAKENHI-PROJECT-24390335

1. TANAKA Fumihiro (10283673)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
2. URAMOTO Hidetaka (90389445)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
3. SO Tomoko (00331529)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YONEDA Kazue (80724806)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. ONAGA Takashi (10416133)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. HASEGAWA Seiki (10252438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OKA Soichi (20596655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. CHIKAISHI Yasuhiro (25861251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. 近石泰弘 (70609221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KATAYORI Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OIZUMI Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 下川秀彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SO Tomoko 宗 知子

Research Projects

Research Products

Co-Researchers

Development of a sensitive system for capturing circulating tumor cells in lung cancer.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of molecular mechanism forEML4-ALK/ EGFR-TKI resistance and establishment of less invasive diagnosis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Blood biomarker in malignant pleural mesothelioma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of high sensitivity detection method of CTCs in lung cancer using microfluidic chip system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] ZEB1 Mediates Acquired Resistance to the Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] rognostic impact of clinical variables on surgically resected small-cell lung cancer: Results of a retrospective multicenter analysis (FIGHT002A and HOT1301A)2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Erlotinib resistance in lung cancer cells mediated by integrinβ1/Src/Akt-driven bypass signaling2013

Author(s)

Journal Title

Data Source

[Journal Article] Prognostic implications of human leukocyte antigen class I expression in patients who underwent surgical resection for non-small cell lung cancer.2013

Author(s)

Journal Title

Data Source

[Journal Article] Intrapleural chemotherapy improves the survival of non-small cell lung cancer patients with positive pleural lavage cytology.2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Discriminative features of thin-slice CT for peripheral intrapulmonary lymph nodes.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic implications of human leukocyte antigen class I expression in patients who underwent surgical resection for non-small-cell lung cancer2013

Author(s)

Journal Title

Data Source

[Journal Article] Clinical Significance of Expression of Cancer/testis Antigen and Down-regulation of HLA Class-I in Patients with Stage I Non-small Cell Lung Cancer2013

Author(s)

Journal Title

Data Source

[Journal Article] Serum Level of Osteopontin as a Prognostic Factor in Patients Who Underwent Surgical Resection for Non-Small-Cell Lung Cancer2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical significance of the frequency of regulatory T cells in regional lymph node lymphocytes as a prognostic factor for non-small-cell lung cancer.2013

Author(s)

Journal Title

Data Source

[Presentation] Capture of EpCAM-negative circulating tumor cells (CTCs) with a “Universal CTC-Chip”.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

SO Tomoko 宗知子

[Journal Article] Clinical Significance of Expression of　Cancer/testis Antigen and Down-regulation of HLA Class-I in Patients with Stage I　Non-small Cell Lung Cancer2013