NISHIKAWA Manabu 西川学

Researcher Number	00347494
Other IDs
Affiliation (based on the past Project Information) *help	2008: 大阪市大, 医学(系)研究科(研究院), 助教 2007: Osaka City University, 大学院・医学研究科, 助教 2006: 大阪市立大学, 大学院・医学研究科, 助手 2005: 大阪市立大学, 大学院医学研究科, 助手 2002 – 2004: 大阪市立大学, 大学院・医学研究科, 助手
Review Section/Research Field	Principal Investigator Laboratory medicine / Pathological medical chemistry / Biological Sciences Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 炎症 / ミトコンドリアDNA / ミトコンドリア / 活性酸素 / 酸化ストレス / 慢性肝炎 / 肝癌 / 発癌 / 遺伝子変異 / 発がん … More / カルニチン / インターフェロン / 癌 / mtDNA / ミトコンドリア遺伝子 / 潰瘍性大腸炎 / 大腸癌 … More Except Principal Investigator oxidative stress / mitochondrial DNA / mitochondria / hepatoma / chronic hepatitis / インターフェロン / 肝発癌 / 塩基変異 / 酸化ストレス / ミトコンドリアDNA / ミトコンドリア / 肝癌 / 慢性肝炎 Less

ミトコンドリアゲノム解析による発がん危機管理法開発Principal Investigator
- Principal Investigator
  
  西川学
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka City University
ミトコンドリアゲノム解析と発癌危機管理に関する総括的研究Principal Investigator
- Principal Investigator
  
  西川学
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University
ミトコンドリア遺伝子異常と発癌に関する総括的研究Principal Investigator
- Principal Investigator
  
  西川学
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka City University
The relationship between mtDNA injury and hepalocarcinogenesis in chronic hepatitis.
- Principal Investigator
  
  NISHIGUCHI Shuhei
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University

All 2007 2006 2005 2004 2003 2002 2001 Other

All Journal Article Presentation Book

[Book] ゲノム医学「肝発癌とミトコンドリア遺伝子異常」2004
- Author(s)
  西川学, 西口修平, 井上正康
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-15790165
[Book] ミトコンドリアとミトコンドリア病「発癌とミトコンドリア遺伝子」2002
- Author(s)
  西川学, 井上正康
- Total Pages
  804
- Publisher
  日本臨床社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13670546
[Journal Article] Identification and characterization of endoplasmic reticulum-associated protein,ERp43.2007
- Author(s)
  Nishikawa M, Kira Y, Yabunaka Y, et. al.
- Journal Title
  
  Gene 386
  
  Pages: 42-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590535
[Journal Article] Identification and characterization of endoplasmic reticulum-associated protein, ERp43.2007
- Author(s)
  Nishikawa M, Kira Y, Yabunaka Y, Inoue M.
- Journal Title
  
  Gene 386
  
  Pages: 42-51
- Data Source
  KAKENHI-PROJECT-18590535
[Journal Article] A possible cooperation of SOD1 and cytochrome c in mitochondria-dependent apoptosis.2006
- Author(s)
  Li Q, Sato EF, Kira Y, Nishikawa M, Utsumi K, Inoue M.
- Journal Title
  
  Free Radic Biol Med 40
  
  Pages: 173-81
- Data Source
  KAKENHI-PROJECT-18590535
[Journal Article] L-carnitine suppresses the onset of neuromuscular degeneration and increases the life span of mice with familial amyotrophic lateral sclerosis.2006
- Author(s)
  Kira Y, Nishikawa M, Ochi A, Sato E, Inoue M.
- Journal Title
  
  Brain Res 1070
  
  Pages: 206-14
- Data Source
  KAKENHI-PROJECT-18590535
[Journal Article] Mannose-conjugated alendronate selectively depletes Kupffer cells and inhibits endotoxemic shock in the mice.2006
- Author(s)
  Hirose M, Nishikawa M, Qian W, Haque A, Mashimo M, Inoue M.
- Journal Title
  
  Hepatol Res 36
  
  Pages: 3-10
- NAID
  10018774193
- Data Source
  KAKENHI-PROJECT-18590535
[Journal Article] Lack of mitochondrial DNA enhances growth of hepatocellular carcinoma in vitro and in vivo.2006
- Author(s)
  Haque A, Nishikawa M, Qian W, Mashimo M, Hirose M, Nishiguchi S, Inoue M.
- Journal Title
  
  Hepatol Res 36
  
  Pages: 209-16
- NAID
  10018640249
- Data Source
  KAKENHI-PROJECT-18590535
[Journal Article] L-carnitine suppresses the onset of neuromuscular degeneration and increases the life span of mice with familial amyotrophic lateral sclerosis.2006
- Author(s)
  Kira Y, Nishikawa M, Ochi A, Sato E, Inoue M
- Journal Title
  
  Brain Res 1070
  
  Pages: 206-214
- Data Source
  KAKENHI-PROJECT-15790165
[Journal Article] Production of reactive oxygen species in peripheral blood is increased in individuals with Helicobacter pylori infection and decreased after its eradication.2006
- Author(s)
  Mashimo M, Nishikawa M, Higuchi K, Hirose M, Wei Q, Haque A, Sasaki E, Shiba M, Tominaga K, Watanabe T, Fujiwara Y, Arakawa T, Inoue M.
- Journal Title
  
  Helicobacter 11
  
  Pages: 266-71
- Data Source
  KAKENHI-PROJECT-18590535
[Journal Article] Accumulation of mitochondrial DNA mutation with colorectal carcinogenesis in ulcerative colitis2005
- Author(s)
  Nishikawa M, Oshitani N, Matsumoto T, Nishigami T, Arakawa T, Inoue M
- Journal Title
  
  Br J Cancer 93
  
  Pages: 331-337
- Data Source
  KAKENHI-PROJECT-15790165
[Journal Article] L-carnitine inhibits hepatocarcinogenesis via protection of mitochondria.2005
- Author(s)
  Chang B, Nishikawa M, Nishiguchi S, Inoue M.
- Journal Title
  
  Int J Cancer 113
  
  Pages: 719-729
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13670546
[Journal Article] L-carnitine inhibits hepatocarcinogenesis via protection of mitochondria.2005
- Author(s)
  Chang B, Nishikawa M, Nishiguchi S, Inoue M.
- Journal Title
  
  Int J Cancer. 113(5)
  
  Pages: 719-729
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670546
[Journal Article] L-carnitine inhibits hypoglycemia-induced brain damage in the rat.2005
- Author(s)
  Hino K, Nishikawa M, Sato E, Inoue M
- Journal Title
  
  Brain Res 1053
  
  Pages: 77-87
- Data Source
  KAKENHI-PROJECT-15790165
[Journal Article] L-carnitine inhibits hepatocarcinogenesis via protection of mitochondria.2005
- Author(s)
  Chang B, Nishikawa M, Nishiguchi S, Inoue M.
- Journal Title
  
  Int J Cancer 113
  
  Pages: 719-729
- Data Source
  KAKENHI-PROJECT-15790165
[Journal Article] Mitochondrial density determines the cellular sensitivity to cisplatin-induced cell death2005
- Author(s)
  Qian W, Nishikawa M, Haque AM, Hirose M, Mashimo M, Sato E, Inoue M
- Journal Title
  
  Am J Physiol Cell Physiol 289
- Data Source
  KAKENHI-PROJECT-15790165
[Journal Article] Interferon reduces somatic mutation of mitochondrial DNA in liver tissues from chronic viral hepatitis patients.2005
- Author(s)
  Nishikawa M, Nishiguchi S, Kioka K, Tamori A, Inoue M
- Journal Title
  
  J Viral Hepat 12
  
  Pages: 494-498
- Data Source
  KAKENHI-PROJECT-15790165
[Journal Article] Correlation between clinical characteristics and mitochondrial D-loop DNA mutations in hepatocellular carcinoma.2004
- Author(s)
  Tamori A, Nishiguchi S, Nishikawa M, Kubo S, Koh N, Hirohashi K, Shiomi S, Inoue M.
- Journal Title
  
  J Gastroenterol. 39
  
  Pages: 1063-1068
- NAID
  10014116216
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13670546
[Journal Article] Interferon reduces Somatic Mutation of Mitochondrial DNA in Liver Tissues from Chronic Viral Hepatitis Patients.2004
- Author(s)
  Nishikawa M, Nishiguchi S, Kioka K, Tamori A, Inoue M.
- Journal Title
  
  J.Vral Hepatitis 11
  
  Pages: 1-5
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13670546
[Journal Article] Correlation between clinical characteristics and mitochondrial D-loop DNA mutations in hepatocellular carcinoma.2004
- Author(s)
  Tamori A, Nishiguchi S, Nishikawa M, Kubo S, Koh N, Hirohashi K, Shiomi S, Inoue M.
- Journal Title
  
  J Gastroenterol. 39
  
  Pages: 1063-1068
- NAID
  10014116216
- Data Source
  KAKENHI-PROJECT-15790165
[Journal Article] Multicentric occurrence of hepatocellular carcinoma in patients with a somatic mutation of mitochondorial DNA and hepatitis C virus.2004
- Author(s)
  Kubo S, Nishikawa M, Hirohashi K, Tanaka H, Shuto T, Tamori A, Kinoshita H, Inoue M, Nishiguchi S.
- Journal Title
  
  Hepatol Res. 25
  
  Pages: 78-82
- NAID
  10016176177
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13670546
[Journal Article] Correlation between clinical characteristics and mitochondrial D-loop DNA mutations in hepatocellular carcinoma.2004
- Author(s)
  Tamori A, Nishiguchi S, Nishikawa M, Kubo S, Koh N, Hirohashi K, Shiomi S, Inoue M.
- Journal Title
  
  J Gastroenterol. 39(11)
  
  Pages: 1063-1068
- NAID
  10014116216
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670546
[Journal Article] Multicentric occurrence of hepatocellular carcinoma in patients with a somatic mutation of mitochondorial DNA and hepatitis C virus.2003
- Author(s)
  Kubo S, Nishikawa M, Hirohashi K, Tanaka H, Shuto T, Tamori A, Kinoshita H, Inoue M, Nishiguchi S.
- Journal Title
  
  Hepatol Res. 25(1)
  
  Pages: 78-82
- NAID
  10016176177
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670546
[Journal Article] Somatic mutation of mitochondrial DNA in cancerous and noncancerous liver tissue in individuals with hepatocellular carcinoma.2001
- Author(s)
  Nishikawa M, Nishiguchi S, Shiomi S, Tamori A, Koh N, Takeda T, Kubo S, Hirohashi K, Kinoshita H, Sato E, Inoue M.
- Journal Title
  
  Cancer Res. 61(5)
  
  Pages: 1843-1845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670546
[Journal Article] Somatic mutation of mitochondrial DNA in cancerous and noncancerous liver tissue in individuals with hepatocelluar carcinoma.2001
- Author(s)
  Nishikawa M, Nishiguchi S, Shiomi S, Tamori A, Koh N, Takeda T, Kubo S, Hirohashi K, Kinoshita H, Sato E, Inoue M.
- Journal Title
  
  Cancer Res. 61
  
  Pages: 1843-1845
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13670546
[Journal Article] Interferon reduces Somatic Mutation of Mitochondrial DNA in Liver Tissues from Chronic Viral Hepatitis Patients.
- Author(s)
  Nishikawa M, Nishiguchi S, Kioka K, Tamori A, Inoue M.
- Journal Title
  
  J.Viral Hepatitis (In press)
- Data Source
  KAKENHI-PROJECT-15790165
[Journal Article] Molecular alterations in hepatocellular carcinoma associated with viral eradication by interferon therapy for chronic hepatitis C
- Author(s)
  Hayashi T, Tamori A, Nishikawa M, et. al.
- Journal Title
  
  Liver International (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590535
[Journal Article] Interferon reduces Somatic Mutation of Mitochondrial DNA in Liver Tissues from Chronic Viral Hepatitis Patients.
- Author(s)
  Nishikawa M, Nishiguchi S, Kioka K, Tamori A, Inoue M.
- Journal Title
  
  J.Viral Hepatitis. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670546
[Journal Article] Identification and characterization of a new GTP-binding protein(Gbp45) involved in cell proliferation and death related to mitochondrial function
- Author(s)
  Kira Y, Nishikawa M.
- Journal Title
  
  Cellular & Molecular Biology Letters (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590535
[Presentation] Mitochondrial dynamism in Hepatocarcinogenesis2007
- Author(s)
  西川学
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-18590535

1. NISHIGUCHI Shuhei (10192246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. TAMORI Akihiro (30291595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. SHIOMI Susumu (30170848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

NISHIKAWA Manabu 西川 学

Research Projects

Research Products

Co-Researchers

ミトコンドリアゲノム解析による発がん危機管理法開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ミトコンドリアゲノム解析と発癌危機管理に関する総括的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ミトコンドリア遺伝子異常と発癌に関する総括的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The relationship between mtDNA injury and hepalocarcinogenesis in chronic hepatitis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] ゲノム医学「肝発癌とミトコンドリア遺伝子異常」2004

Author(s)

Publisher

Data Source

[Book] ミトコンドリアとミトコンドリア病「発癌とミトコンドリア遺伝子」2002

Author(s)

Total Pages

Publisher

Description

Data Source

[Journal Article] Identification and characterization of endoplasmic reticulum-associated protein,ERp43.2007

Author(s)

Journal Title

Data Source

[Journal Article] Identification and characterization of endoplasmic reticulum-associated protein, ERp43.2007

Author(s)

Journal Title

Data Source

[Journal Article] A possible cooperation of SOD1 and cytochrome c in mitochondria-dependent apoptosis.2006

Author(s)

Journal Title

Data Source

[Journal Article] L-carnitine suppresses the onset of neuromuscular degeneration and increases the life span of mice with familial amyotrophic lateral sclerosis.2006

Author(s)

Journal Title

Data Source

[Journal Article] Mannose-conjugated alendronate selectively depletes Kupffer cells and inhibits endotoxemic shock in the mice.2006

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Lack of mitochondrial DNA enhances growth of hepatocellular carcinoma in vitro and in vivo.2006

Author(s)

Journal Title

NAID

Data Source

[Journal Article] L-carnitine suppresses the onset of neuromuscular degeneration and increases the life span of mice with familial amyotrophic lateral sclerosis.2006

Author(s)

Journal Title

Data Source

[Journal Article] Production of reactive oxygen species in peripheral blood is increased in individuals with Helicobacter pylori infection and decreased after its eradication.2006

Author(s)

Journal Title

Data Source

[Journal Article] Accumulation of mitochondrial DNA mutation with colorectal carcinogenesis in ulcerative colitis2005

Author(s)

Journal Title

Data Source

[Journal Article] L-carnitine inhibits hepatocarcinogenesis via protection of mitochondria.2005

Author(s)

Journal Title

Description

NISHIKAWA Manabu 西川学