Yamashiro Kazuo 山城一雄

… Alternative Names

YAMASHIRO Kazuo 山城一雄

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Researcher Number	00348921
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 先任准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 順天堂大学, 医学部, 先任准教授 2015 – 2019: 順天堂大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Food science
Keywords	Principal Investigator 腸内細菌 / 神経炎症 / 糖尿病 / 脳梗塞 / 短鎖脂肪酸 / 認知症 / プロバイオティクス / Tリンパ球 / T細胞 / 自然免疫 … More / Toll-like receptor 4 / 急性期脳梗塞 / 腸内細菌叢 / lipopolysaccharide / 炎症 / トル様受容体 / Lipopolysaccharide Less

短鎖脂肪酸の神経炎症抑制効果と作用メカニズムの解明Principal Investigator
- Principal Investigator
  
  山城一雄
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Juntendo University
腸内細菌による神経炎症メカニズムの解明Principal Investigator
- Principal Investigator
  
  山城一雄
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Juntendo University
Intestinal T cells and probiotics treatment in acute ischemic strokePrincipal Investigator
- Principal Investigator
  
  Yamashiro Kazuo
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Juntendo University
Role of the gut microbiota in acute cerebral ischemiaPrincipal Investigator
- Principal Investigator
  
  YAMASHIRO Kazuo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Juntendo University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Microbial lipopolysaccharide‐induced inflammation contributes to cognitive impairment and white matter lesion progression in diet‐induced obese mice with chronic cerebral hypoperfusion2023
- Author(s)
  Inaba Toshiki、Yamashiro Kazuo、Kurita Naohide、Ueno Yuji、Miyamoto Nobukazu、Hira Kenichiro、Nakajima Sho、Kijima Chikage、Nakaguro Ryohei、Urabe Takao、Hattori Nobutaka
- Journal Title
  
  CNS Neuroscience & Therapeutics
  
  Volume: 29 Issue: S1 Pages: 200-212
- DOI
  10.1111/cns.14301
- Data Source
  KAKENHI-PROJECT-21K05443
[Journal Article] Role of the Gut Microbiota in Stroke Pathogenesis and Potential Therapeutic Implications2021
- Author(s)
  Yamashiro Kazuo、Kurita Naohide、Urabe Takao、Hattori Nobutaka
- Journal Title
  
  Annals of Nutrition and Metabolism
  
  Volume: 77 Issue: Suppl. 2 Pages: 36-44
- DOI
  10.1159/000516398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05492, KAKENHI-PROJECT-21K05443
[Journal Article] Metabolic endotoxemia promotes neuroinflammation after focal cerebral ischemia2020
- Author(s)
  Kurita Naohide、Yamashiro Kazuo、Kuroki Takuma、Tanaka Ryota、Urabe Takao、Ueno Yuji、Miyamoto Nobukazu、Takanashi Masashi、Shimura Hideki、Inaba Toshiki、Yamashiro Yuichiro、Nomoto Koji、Matsumoto Satoshi、Takahashi Takuya、Tsuji Hirokazu、Asahara Takashi、Hattori Nobutaka
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism
  
  Volume: 印刷中 Issue: 12 Pages: 2505-2520
- DOI
  10.1177/0271678x19899577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09764, KAKENHI-PROJECT-18K05492
[Presentation] Gut microbial LPS-induced neuroinflammation and cognitive impairment in diet-induced obese mice.2023
- Author(s)
  Inaba T, Yamashiro K, Kurita N, Ueno Y, Miyamoto N, Hira K, Nakajima S, Kijima C, Nakaguro R, Urabe T, Hattori N.
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] アルツハイマー病における神経炎症は腸内細菌叢異常と関連する2023
- Author(s)
  山城一雄、高林海斗、鎌形康司、西本悠一郎、山内洋輔、大垣光太郎、波田野琢、青木茂樹、卜部貴夫、服部信孝
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] 肥満、腸内細菌と脳小血管病2023
- Author(s)
  山城一雄、卜部貴夫、服部信孝
- Organizer
  第48回日本脳卒中学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] 肥満・メタボリックシンドロームと脳卒中リスク2023
- Author(s)
  山城一雄、卜部貴夫、服部信孝
- Organizer
  第48回日本脳卒中学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] 細菌由来LPSによる神経炎症と認知機能障害および白質病変との関連2023
- Author(s)
  山城一雄、稲葉俊東、卜部貴夫、服部信孝
- Organizer
  第13回日本脳血管認知症学会年会
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] 脳卒中における栄養と腸内細菌代謝物の影響2023
- Author(s)
  山城一雄、卜部貴夫、服部信孝
- Organizer
  第48回日本脳卒中学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] 認知症における脳内炎症と腸内細菌2023
- Author(s)
  山城一雄、高林海斗、鎌形康司、西本悠一郎、山内洋輔、大垣光太郎、波田野琢、青木茂樹、卜部貴夫、服部信孝
- Organizer
  第66回日本脳循環代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] 腸内細菌LPSによる認知機能と白質病変への影響2022
- Author(s)
  稲葉俊東、山城一雄、栗田尚英、上野祐司、宮元伸和、平健一郎、中島翔、木島千景、服部信孝、卜部貴夫.
- Organizer
  第65回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] Gut microbial LPS contributes cognitive impairment and white matter lesions via neuroinflammation2022
- Author(s)
  Inaba T, Yamashiro K, Kurita N, Ueno Y, Miyamoto N, Hira K, Nakajima S, Kijima C, Nakaguro R, Urabe T, Hattori N.
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] 腸内細菌叢異常は神経炎症を介して認知機能と白質病変に関与する2021
- Author(s)
  稲葉俊東、山城一雄、栗田尚英、上野祐司、宮元伸和、平健一郎、中島翔、木島千景、服部信孝、卜部貴夫
- Organizer
  第64回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] 腸内細菌叢異常は神経炎症を介して認知機能と白質病変に関与する2021
- Author(s)
  稲葉俊東、山城一雄、栗田尚英、上野祐司、宮元伸和、平健一郎、中島翔、木島千景、服部信孝
- Organizer
  第64回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] 脳卒中の病態における腸内細菌の役割2021
- Author(s)
  山城一雄、栗田尚英、服部信孝、卜部貴夫
- Organizer
  第46回日本脳卒中学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] 腸内細菌由来LPSによる神経炎症と認知機能及び白質病変との関連2021
- Author(s)
  山城一雄、稲葉俊東、栗田尚英、上野祐司、宮元伸和、平健一郎、中島翔、木島千景、服部信孝、卜部貴夫
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] 脳卒中の病態における腸内細菌の役割2021
- Author(s)
  山城一雄、栗田尚英、服部信孝、卜部貴夫
- Organizer
  第46回日本脳卒中学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] 腸内細菌由来LPSによる神経炎症と認知機能及び白質病変との関連2021
- Author(s)
  山城一雄、稲葉俊東、栗田尚英、上野祐司、宮元伸和、平健一郎、中島翔、木島千景、服部信孝、卜部貴夫
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] LPSによる神経炎症が認知機能と白質病変に及ぼす影響2021
- Author(s)
  山城一雄、稲葉俊東、栗田尚英、上野祐司、宮元伸和、平健一郎、中島翔、木島千景、服部信孝、卜部貴夫
- Organizer
  第11回日本脳血管・認知症学会総会
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] LPSによる神経炎症が認知機能と白質病変に及ぼす影響2021
- Author(s)
  山城一雄、稲葉俊東、栗田尚英、上野祐司、宮元伸和、平健一郎、中島翔、木島千景、服部信孝、卜部貴夫
- Organizer
  第11回日本脳血管・認知症学会総会
- Data Source
  KAKENHI-PROJECT-21K05443
[Presentation] Metabolic endotoxemia promotes neuroinflammation after focal cerebral ischemia2020
- Author(s)
  山城一雄
- Organizer
  The joint European Stroke Organisation and World Stroke Organisation Conference (ESO-WSO 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] Gut dysbiosis promotes LPS-induced neuroinflammation after cerebral ischemia in diabetic mice2019
- Author(s)
  Naohide Kurita, Kazuo Yamashiro, Takuma Kuroki, Ryota Tanaka, Yuji Ueno, Takao Urabe, Nobutaka Hattori
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] 腸内細菌叢の異常と脳虚血急性期におけるLPSを介した炎症2019
- Author(s)
  栗田尚英、山城一雄、黒帰卓馬、田中亮太、上野祐司、宮元伸和、卜部貴夫、山城雄一郎、服部信孝
- Organizer
  第44回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] Modulation of gut microbiota improves outcomes after ischemic stroke by reducing lipopolysaccharide-induced inflammation in the ischemic brain of diabetic mice2019
- Author(s)
  Kurita N, Yamashiro K, Kuroki K, Tanaka R, Ueno Y, Urabe T, Yamashiro Y, Hattori N.
- Organizer
  International Stroke Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] Gut dysbiosis promotes lipopolysaccharide-induced neuroinflammation after stroke.2019
- Author(s)
  Naohide Kurita, Kazuo Yamashiro, Ryota Tanaka, Yuji Ueno, Nobukazu Miyamoto, Sho Nakajima Takao Urabe, Yuichiro Yamashiro, Nobutaka Hattori.
- Organizer
  BRAIN and BRAIN PET 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] 腸内細菌と脳卒中2019
- Author(s)
  山城一雄
- Organizer
  第44回日本脳卒中学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] Stroke and Microbiota2019
- Author(s)
  山城一雄、服部信孝
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] 糖尿病マウスの腸内細菌叢異常は脳梗塞巣において内毒素に起因する炎症を引き起こす2018
- Author(s)
  栗田尚英、山城一雄、黒木卓馬、田中亮太、上野祐司、卜部貴夫、野本康二、松本敏、高橋琢也、辻浩和、朝原崇、山城雄一郎、服部信孝
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] Modulation of gut microbiota improves outcomes after stroke by reducing lipopolysaccharide-induced inflammation in the ischemic brain in diabetic mice.2018
- Author(s)
  Kurita N, Yamashiro K, Kuroki T, Tanaka R, Ueno Y, Urabe T, Yamashiro Y, Hattori N.
- Organizer
  4th European Stroke Organization Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05492
[Presentation] 腸内細菌叢の異常に伴う高LPS血症と急性期脳梗塞における組織障害の進展2018
- Author(s)
  1.栗田尚英、山城一雄、黒木卓馬、田中亮太、上野祐司、卜部貴夫、山城雄一郎、野本康二、松本敏、高橋琢也、辻浩和、朝原崇、服部信孝
- Organizer
  第43回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-15K07439
[Presentation] MODULATION OF GUT MICROBIOTA REDUCES ACUTE FOCAL CEREBRAL ISCHEMIA/REPERFUSION INJURY IN TYPE 2 DIABETIC MICE2017
- Author(s)
  Kazuo Yamashiro, Naohide Kurita, Takuma Kuroki, Ryota Tanaka, Takao Urabe, Koji Nomoto, Takuya Takahashi, Hirokazu Tsuji, Takashi Asahara, Yuichiro Yamashiro and Nobutaka Hattori.
- Organizer
  3rd European Stroke Organisation Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07439
[Presentation] 糖尿病マウスにおける腸内細菌叢の異常と急性期脳梗塞巣の組織障害2017
- Author(s)
  栗田尚英、山城一雄、田中亮太、上野祐司、山城雄一郎、野本康二、高橋琢也、辻浩和、朝原崇、服部信孝
- Organizer
  第42回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-15K07439
[Presentation] Gut dysbiosis induces lipopolysaccharide-mediated inflammation after cerebral ischemia in type 2 diabetic mice2017
- Author(s)
  Naohide Kurita, Kazuo Yamashiro, Takuma Kuroki, Ryota Tanaka, Yuji Ueno, Takao Urabe, Koji Nomoto, Takuya Takahashi, Hirokazu Tsuji, Takashi Asahara, Yuichiro Yamashiro and Nobutaka Hattori.
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07439
[Presentation] 腸内細菌叢の異常に伴う高LPS血症は急性期脳梗塞の組織障害進展に関与する2017
- Author(s)
  栗田尚英、山城一雄、黒木卓馬、田中亮太、上野祐司、卜部貴夫、山城雄一郎、野本康二、松本敏、高橋琢也、辻浩和、朝原崇、服部信孝
- Organizer
  第60回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-15K07439
[Presentation] 急性期脳梗塞における腸内細菌の関与2016
- Author(s)
  栗田尚英、山城一雄、黒木卓馬、上野祐司、田中亮太、山城雄一郎、野本康二、高橋琢也、辻浩和、朝原崇、服部信孝
- Organizer
  第41回日本脳卒中学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-15K07439
[Presentation] 急性期脳梗塞における腸内細菌の関与2016
- Author(s)
  栗田尚英、山城一雄、黒木卓馬、上野祐司、田中亮太、山城雄一郎、野本康二、高橋琢也、辻浩和、朝原崇、服部信孝
- Organizer
  第59回日本脳循環代謝学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-15K07439
[Presentation] Systemic inflammation and exacerbated brain damage to transient focal ischemia in type 2 diabetic mice.2015
- Author(s)
  山城一雄
- Organizer
  XXVIIth International symposium on cerebral blood flow, metabolism and function.
- Place of Presentation
  Vancouver, Canada.
- Year and Date
  2015-06-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07439

1. HATTORI Nobutaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. TANAKA Ryota

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. KUROKI Takuma

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. KURITA Naohide

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. NOMOTO Koji

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. TAKAHASHI Takuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. YAMASHIRO Yuichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. 上野祐司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamashiro Kazuo 山城 一雄

YAMASHIRO Kazuo 山城 一雄

Research Projects

Research Products

Co-Researchers

短鎖脂肪酸の神経炎症抑制効果と作用メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腸内細菌による神経炎症メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Intestinal T cells and probiotics treatment in acute ischemic strokePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of the gut microbiota in acute cerebral ischemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Microbial lipopolysaccharide‐induced inflammation contributes to cognitive impairment and white matter lesion progression in diet‐induced obese mice with chronic cerebral hypoperfusion2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of the Gut Microbiota in Stroke Pathogenesis and Potential Therapeutic Implications2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic endotoxemia promotes neuroinflammation after focal cerebral ischemia2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Gut microbial LPS-induced neuroinflammation and cognitive impairment in diet-induced obese mice.2023

Author(s)

Organizer

Data Source

[Presentation] アルツハイマー病における神経炎症は腸内細菌叢異常と関連する2023

Author(s)

Organizer

Data Source

[Presentation] 肥満、腸内細菌と脳小血管病2023

Author(s)

Organizer

Data Source

[Presentation] 肥満・メタボリックシンドロームと脳卒中リスク2023

Author(s)

Organizer

Data Source

[Presentation] 細菌由来LPSによる神経炎症と認知機能障害および白質病変との関連2023

Author(s)

Organizer

Data Source

[Presentation] 脳卒中における栄養と腸内細菌代謝物の影響2023

Author(s)

Organizer

Data Source

[Presentation] 認知症における脳内炎症と腸内細菌2023

Author(s)

Organizer

Data Source

[Presentation] 腸内細菌LPSによる認知機能と白質病変への影響2022

Author(s)

Organizer

Data Source

[Presentation] Gut microbial LPS contributes cognitive impairment and white matter lesions via neuroinflammation2022

Author(s)

Organizer

Data Source

Yamashiro Kazuo 山城一雄

YAMASHIRO Kazuo 山城一雄