Azuma Koichi 東公一

… Alternative Names

Koichi Azuma 東公一

AZUMA Koichi 東公一

AZUMA Koishi 東公一

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Researcher Number	00368896
Other IDs
Affiliation (Current)	2025: 久留米大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 久留米大学, 医学部, 講師 2017: 久留米大学, 医学部, 助教 2012 – 2014: 久留米大学, 医学部, 講師 2007 – 2008: Kurume University, 医学部, 助教
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine Except Principal Investigator General surgery / Radiation science
Keywords	Principal Investigator 非小細胞肺癌 / 免疫寛容 / EGFR遺伝子変異 / ニボルマブ / CD8 / NSCLC / PD-1 / EGFR / 炎症性サイトカイン / バイオマーカー … More / 免疫療法 / PD-L1 / PD-1阻害剤 / CXCL2 / 肺癌 / ペプチド / Met / 癌 / 内科 … More Except Principal Investigator 免疫療法 / 細胞表面マーカー / 抗腫瘍効果 / ゼノグラフト / 個別化治療 / 免疫反応 / 遺伝子変異 / 腫瘍免疫 / ネオアンチゲン / FDG-PET/CT / FDG-PET / 癌増殖シグナル伝達因子 / 肺癌 / ＦＤＧ－ＰＥＴ / 核医学 Less

Analysis of neoantigen-specific anti-tumor immune responses and its clinical application for personalized cancer immunotherapy
- Principal Investigator
  
  Sasada Tetsuro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kanagawa Cancer Center Research Institute
Clinical significance of immune escape mechanisms in non-small cell lung cancer patientsPrincipal Investigator
- Principal Investigator
  
  Koichi Azuma
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kurume University
The prognostic analyses by PET/CT and signal transduction pathway in 150 lung cancer patients.
- Principal Investigator
  
  KAIDA Hayato
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kurume University
Identification of Met-derived peptides recognized by CTLs in HLA-A2+ non-small cell lung cancer patientsPrincipal Investigator
- Principal Investigator
  
  AZUMA Koichi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kurume University
Analysis of peptide antibodies derived from EGFR in non-small cell carcinomaPrincipal Investigator
- Principal Investigator
  
  AZUMA Koishi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kurume University

All 2019 2018 2017

All Journal Article Presentation Patent

[Journal Article] Assessment of soluble immune mediators as potential biomarkers during immune checkpoint inhibitor therapy.2019
- Author(s)
  Matsuo N, Azuma K, Sasada T.
- Journal Title
  
  Oncotarget.
  
  Volume: 10 Issue: 20 Pages: 1866-1867
- DOI
  10.18632/oncotarget.26749
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19490, KAKENHI-PROJECT-17H04278, KAKENHI-PROJECT-16H06277
[Journal Article] Association between soluble immune mediators and tumor responses in patients with nonsmall cell lung cancer treated with anti-PD-1 inhibitor.2019
- Author(s)
  Matsuo N, Azuma K, Hattori S, Ohtake J, Kawahara A, Ishii H, Tokito T, Yamada K, Shibata Y, Shimokawaji T, Kondo T, Kato T, Saito H, Yamada K, Sasada T, Hoshino T.
- Journal Title
  
  Int J Cancer.
  
  Volume: 144 Issue: 5 Pages: 1170-1179
- DOI
  10.1002/ijc.31923
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19490, KAKENHI-PROJECT-17H04278, KAKENHI-PROJECT-16K09595, KAKENHI-PROJECT-16K09596, KAKENHI-PROJECT-16H06277
[Journal Article] Prognostic stratification of patients with nasopharyngeal carcinoma based on tumor immune microenvironment.2018
- Author(s)
  Ono T, Azuma K, Kawahara A, Sasada T, Matsuo N, Kakuma T, Kamimura H, Maeda R, Hattori C, On K, Nagata K, Sato F, Chitose SI, Shin B, Aso T, Akiba J, Umeno H.
- Journal Title
  
  Head Neck.
  
  Volume: 40 Issue: 9 Pages: 2007-2019
- DOI
  10.1002/hed.25189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04278
[Journal Article] Association between PD-L1 expression combined with tumor-infiltrating lymphocytes and the prognosis of patients with advanced hypopharyngeal squamous cell carcinoma.2017
- Author(s)
  Ono T, Azuma K, Kawahara A, Sasada T, Hattori S, Sato F, Shin B, Chitose SI, Akiba J, Hirohito U.
- Journal Title
  
  Oncotarget.
  
  Volume: 8 Issue: 54 Pages: 92699-92714
- DOI
  10.18632/oncotarget.21564
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04278, KAKENHI-PROJECT-16K15601
[Patent] がん免疫療法の予後予測のためのバイオマーカー2018
- Inventor(s)
  笹田哲朗、東　公一、松尾規和、星野友昭
- Industrial Property Rights Holder
  笹田哲朗、東　公一、松尾規和、星野友昭
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16K09596
[Patent] がん免疫療法の予後予測のためのバイオマーカー2018
- Inventor(s)
  笹田哲朗、東　公一、松尾規和、星野友昭
- Industrial Property Rights Holder
  笹田哲朗、東　公一、松尾規和、星野友昭
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-16K09596
[Patent] がん免疫療法の予後予測のためのバイオマーカー2018
- Inventor(s)
  笹田哲朗、東公一、松尾規和、星野友昭
- Industrial Property Rights Holder
  地方独立行政法人神奈川県立病院機構、久留米大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-17H04278
[Presentation] B細胞受容体(BCR)のレパトア解析は非小細胞肺がんにおける免疫チェックポイント阻害剤のバイオマーカーとして有用である.2019
- Author(s)
  五十嵐友香, 中原善朗, 松尾規和, 東公一, 笹田哲朗.
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H04278
[Presentation] Early changes in plasma CXCL2 and MMP2 levels predicts the response to anti-PD-1 therapy in non-small-cell lung cancer.2019
- Author(s)
  Matsuo N, Azuma K, Murotani K, Ishii H, Tokito T, Yamada K,Shibata Y, Shimokawaji T, Nakahara Y, Kondo T, Kato T, Saito H, Yamada K, Sasada T, Hoshino T.
- Organizer
  2019 World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04278
[Presentation] Changes of BCR repertoire are predictive biomarker for the efficacy of immune checkpoint inhibitor in NSCLC.2019
- Author(s)
  Yoshiro Nakahara, Norikazu Matsuo, Koichi Azuma, Yoshiko Naito, Hidenobu Ishii, Takaaki Tokito, Yuka Igarashi, Taku Kouro, Ryo Usui, Tadasuke Shimokawaji, Tetsuro Kondo, Terufumi Kato, Haruhiro Saito, KouzoYamada, Tomoaki Hoshino, Tetsuro Sasada.
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04278
[Presentation] Changes of BCR Repertoire Are Predictive Biomarker for the Efficacy of Immune Checkpoint Inhibitor in NSCLC.2019
- Author(s)
  Azuma K, Nakahara Y, Matsuo N, Ishii H, Tokito T, Murotani K, Hoshino T, Sasada T.
- Organizer
  2019 World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04278
[Presentation] Changes in plasma CXCL2 and MMP2 levels reflect response to anti-PD-1 therapy in non-small-cell lung cancer patients.2019
- Author(s)
  Norikazu Matsuo, Koichi Azuma, Kenta Murotani, Yoshiko Naito, Hidenobu Ishii, Takaaki Tokito, Tadasuke Shimokawaji, Yoshiro Nakahara, Tetsuro Kondo, Terufumi Kato Haruhiro Saito, Kouzo Yamada, Tetsuro Sasada, Tomoaki Hoshino.
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04278
[Presentation] Potential biomarkers in non-small cell lung cancer patients treated with anti-PD-1 inhibitors2018
- Author(s)
  松尾　規和、大竹　淳矢、東　　公一、笹田　哲朗2）
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-16K09596
[Presentation] Inflammatory soluble factors as potential biomarkers in non-small cell lung2018
- Author(s)
  Tetsuro Sasada, Norikazu Matsuo, Junya Ohtake, Koichi Azuma
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09596
[Presentation] Potential biomarkers in non-small cell lung cancer patients treated with anti-PD-1 inhibitors.2018
- Author(s)
  Norikazu Matsuo, Koichi Azuma, Junya Ohtake, Tetsuro Sasada.
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H04278
[Presentation] Inflammatory soluble factors as potential biomarkers in non-small cell lung cancer treated with anti-PD-1 inhibitors.2018
- Author(s)
  Tetsuro Sasada, Norikazu Matsuo, Junya Ohtake, Koichi Azuma.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04278

1. HAYABUCHI Naofumi (20108731)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. ISHIBASHI Masatoshi (20168256)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HATTORI Satoshi (50425154)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Sasada Tetsuro (70293967)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
5. KAIDA Hayato (40299425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUJIMOTO Kiminori (00199366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKAMORI Shinzo (50197028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAGE Masayoshi (80148840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KURATA Seiji (80268888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 高森信三 (50197208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 岸裕幸 (60186210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Matsuo Norikazu

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Azuma Koichi 東 公一

Koichi Azuma 東 公一

AZUMA Koichi 東 公一

AZUMA Koishi 東 公一

Research Projects

Research Products

Co-Researchers

Analysis of neoantigen-specific anti-tumor immune responses and its clinical application for personalized cancer immunotherapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical significance of immune escape mechanisms in non-small cell lung cancer patientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The prognostic analyses by PET/CT and signal transduction pathway in 150 lung cancer patients.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of Met-derived peptides recognized by CTLs in HLA-A2+ non-small cell lung cancer patientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of peptide antibodies derived from EGFR in non-small cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Assessment of soluble immune mediators as potential biomarkers during immune checkpoint inhibitor therapy.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association between soluble immune mediators and tumor responses in patients with nonsmall cell lung cancer treated with anti-PD-1 inhibitor.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic stratification of patients with nasopharyngeal carcinoma based on tumor immune microenvironment.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association between PD-L1 expression combined with tumor-infiltrating lymphocytes and the prognosis of patients with advanced hypopharyngeal squamous cell carcinoma.2017

Author(s)

Journal Title

DOI

Data Source

[Patent] がん免疫療法の予後予測のためのバイオマーカー2018

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] がん免疫療法の予後予測のためのバイオマーカー2018

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] がん免疫療法の予後予測のためのバイオマーカー2018

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] B細胞受容体(BCR)のレパトア解析は非小細胞肺がんにおける免疫チェックポイント阻害剤のバイオマーカーとして有用である.2019

Author(s)

Organizer

Data Source

[Presentation] Early changes in plasma CXCL2 and MMP2 levels predicts the response to anti-PD-1 therapy in non-small-cell lung cancer.2019

Azuma Koichi 東公一

Koichi Azuma 東公一

AZUMA Koichi 東公一

AZUMA Koishi 東公一