Igawa Ken 井川健

… Alternative Names

Researcher Number	00372441
Other IDs
Affiliation (Current)	2022: 獨協医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2022: 獨協医科大学, 医学部, 教授 2019 – 2020: 獨協医科大学, 医学部, 教授 2017: 獨協医科大学, 医学部, 教授 2016: 東京医科歯科大学, 医歯学総合病院, 准教授 2015 – 2016: 東京医科歯科大学, 医学部附属病院, 准教授 … More
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related Except Principal Investigator Dermatology / Basic Section 53050:Dermatology-related
Keywords	Principal Investigator アトピー性皮膚炎 / 表皮角化細胞 / アレルギー / iPS細胞 / 人工ヌクレアーゼ / フィラグリン / 角化細胞 / ゲノム編集 / ケモカイン / IgE … More Except Principal Investigator iPS細胞 / 好塩基球 / 痒疹 / TH2サイトカイン / M2マクロファージ / STAT6 / IgE / プロテアーゼ / 蕁麻疹 / ＴＨ２サイトカイン / ＩｇＥ / ヒト / 人工ヌクレアーゼ / 表皮角化細胞 / CD40リガンド / トランスジェニックマウス / アトピー性皮膚炎 / 脱毛症 / モデルマウス / 膠原病 / revertant mosaicism / 遺伝性皮膚疾患 / CRISPR/Cas9 / 相同組換え / Loss Of Heterozygosity / ブルーム遺伝子 / トiPS細胞 / ガドリニウムイオン / ガドリニウム造影剤 / リプログラミング / 線維芽細胞 / ガドリニウム / 腎性全身性線維症 / CD34 Less

アトピー性皮膚炎におけるMAIT細胞の役割を明らかにするPrincipal Investigator
- Principal Investigator
  
  井川健
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Dokkyo Medical University
ガドリニウム刺激による皮膚線維芽細胞のリプログラミングの可能性
- Principal Investigator
  
  林周次郎
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Dokkyo Medical University
Examination of 'true' meanings of filaggrin mutation in human epidermal keratinocytes.Principal Investigator
- Principal Investigator
  
  IGAWA KEN
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Dokkyo Medical University
  Tokyo Medical and Dental University
Analysis of cutaneous lesion in collagen disease induced by intranuclear autoantibody.
- Principal Investigator
  
  HIGUCHI Tetsuya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Toho University
Establishments of the new forward genetic method using homologues recombination in human iPS cells
- Principal Investigator
  
  Yoshimura Yasuhide
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Osaka University
An establishment of novel treatment based for the pathogenesis of untreated allergic skin diseases
- Principal Investigator
  
  Yokozeki Hiroo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Tokyo Medical and Dental University
induction from fibroblast to keratinocyte
- Principal Investigator
  
  SATO HITOMI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Dokkyo Medical University
A trial for the clarification of the precise relationship between filaggrin gene mutation and atopic dermatitis by using human pluripotent stem cellPrincipal Investigator
- Principal Investigator
  
  IGAWA Ken
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Tokyo Medical and Dental University
Approaches of the new therapy development for atopic dermatitis by using RNA interferencePrincipal Investigator
- Principal Investigator
  
  IGAWA Ken
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Osaka University
  Tokyo Medical and Dental University
アトピー性皮膚炎由来の表皮角化細胞における転写調節因子の解析Principal Investigator
- Principal Investigator
  
  井川健
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Tokyo Medical and Dental University

All 2019 2018 2016 2015 2014 2013 2012 2011 2010 2009 2006

All Journal Article Presentation

[Journal Article] Removal of reprogramming transgenes improves the tissue reconstitution potential of keratinocytes generated from human induced pluripotent stem cells.2014
- Author(s)
  Ken Igawaa, Chikara Kokubu, Kosuke Yusa, Kyoji Horie, Yasuhide Yoshimura, Kaori Yamauchi, Hirofumi Suemori, Hiroo Yokozeki, Masashi Toyoda, Nobutaka Kiyokawa, Hajime Okita, Yoshitaka Miyagawa, Hidenori Akutsu, Akihiro Umezawa, Ichiro Katayama, Junji Takeda.
- Journal Title
  
  STEM CELLS Transl Med
  
  Volume: 3 Pages: 992-1001
- DOI
  10.5966/sctm.2013-0179
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-22310118, KAKENHI-PROJECT-24591651, KAKENHI-PROJECT-24615003, KAKENHI-PROJECT-25461665, KAKENHI-PROJECT-25640048, KAKENHI-PROJECT-24241064
[Journal Article] Gene silencing of STAT6 with siRNA ameliorates contact hyper sensitivity and allergic rhinitis.2011
- Author(s)
  Hosoya K, Satoh T, Yamamoto Y, Saeki K, Igawa K, et al
- Journal Title
  
  Allegy
  
  Volume: 66(1) Pages: 124-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791064
[Journal Article] Gene silencing of STAT6 with siRNA ameliorates contact hypersensitivity and allergic rhinitis.2011
- Author(s)
  Hosoya K, Satoh T, Yamamoto Y, Saeki K, Igawa K(10人中5番目)
- Journal Title
  
  Allegy 66(1)
  
  Pages: 124-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791064
[Journal Article] 【アトピー性皮膚炎の正しい治療】アトピー性皮膚炎の新しい治療の展望2010
- Author(s)
  井川健
- Journal Title
  
  医薬ジャーナル 46(3)
  
  Pages: 994-998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791064
[Journal Article] Regulatory mechanisms of galectin-9 and eotaxin-3 synthesis in epidermal keratinocytes : possible involvement of galectin-9 in dermal eosinophilia of Th1-polarized skin inflammation.2006
- Author(s)
  Igawa K, et al.
- Journal Title
  
  Allergy 61(12)
  
  Pages: 1385-1385
- Data Source
  KAKENHI-PROJECT-16790625
[Presentation] Anti-inflammatory effects of potassium iodide in sodium dodecyl sulphate-induced inflammatory murine skin through interleukin-10 regulation.2019
- Author(s)
  Shujiro Hayashi. Satoko Ishikawa, Masami Koike, Tomoko Kaminaga, Yoichiro Hamasaki, Ken Igawa.
- Organizer
  49th Annual ESDR Meeting. Bordeaux, 2019. 9.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08799
[Presentation] iPS細胞の基礎と臨床2018
- Author(s)
  井川　健
- Organizer
  第117回日本皮膚科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09759
[Presentation] To clarify the effect of the filaggrin gene mutation in keratinocytes by using CRISPR/Cas9 system and human induced pluripotent stem cells.2016
- Author(s)
  Ken Igawa
- Organizer
  The 41th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Sendai, Japan
- Year and Date
  2016-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09759
[Presentation] REMOVAL OF REPROGRAMMING TRANSGENES IMPROVES THE TISSUE RECONSTITUTION POTENTIAL OF KERATINOCYTES GENERATED FROM HUMAN INDUCED PLURIPOTENT STEM CELLS.2015
- Author(s)
  Igawa K. et al.
- Organizer
  23rd World Congress of Dermatology 2015
- Place of Presentation
  Vancouver（Canada）
- Year and Date
  2015-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461665
[Presentation] A trial to clarify the effect of the filaggrin gene mutation to keratinocytes biology by using CRISPR/Cas9 system and human induced pluripotent stem cells.2015
- Author(s)
  Igawa K. et al.
- Organizer
  ESDR2015
- Place of Presentation
  Rotterdam（Netherlands）
- Year and Date
  2015-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461665
[Presentation] A trial to clarify the effect of the filaggrin gene mutation to keratinocytes biology by using CRISPR/Cas9 system and human induced pluripotent stem cells.2015
- Author(s)
  Igawa K
- Organizer
  European Society for Dermatological Research 2015
- Place of Presentation
  ロッテルダム、オランダ
- Year and Date
  2015-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09759
[Presentation] REMOVAL OF REPROGRAMMING TRANSGENES IMPROVES THE TISSUE RECONSTITUTION POTENTIAL OF KERATINOCYTES GENERATED FROM HUMAN INDUCED PLURIPOTENT STEM CELLS.2015
- Author(s)
  Igawa K
- Organizer
  World Congress of Dermatology 2015
- Place of Presentation
  バンクーバー、カナダ
- Year and Date
  2015-06-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09759
[Presentation] アトピー性皮膚炎の病型と難治性皮膚病変の関連に関する疫学調査2014
- Author(s)
  野老翔雲、井川　健、戸倉新樹、宮地良樹、片山一朗、佐藤貴浩、横関博雄
- Organizer
  第２６回日本アレルギー学会春季臨床大会
- Place of Presentation
  京都市
- Year and Date
  2014-05-09
- Data Source
  KAKENHI-PROJECT-25461665
[Presentation] Efficient keratinocytes differentiation from transgene-free human induced pluripotent stem cell line: Implication for therapeutic application.2013
- Author(s)
  Igawa K
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-24591651
[Presentation] Efficient keratinocytes differentiation from transgene-free human induced pluripotent stem cell line: Implication for therapeutic application.2013
- Author(s)
  井川　健
- Organizer
  第8回　箱根カンファレンス
- Place of Presentation
  淡路島
- Invited
- Data Source
  KAKENHI-PROJECT-24591651
[Presentation] Efficient keratinocytes differentiation from transgene-free human induced pluripotent stem cell line:Implication for therapeutic application.2013
- Author(s)
  IGAWA K.
- Organizer
  第8回　箱根カンファレンス
- Place of Presentation
  兵庫県淡路島淡路夢舞台
- Data Source
  KAKENHI-PROJECT-25461665
[Presentation] Efficient keratinocytes differentiation from transgene-free human induced pluripotent stem cell line.2013
- Author(s)
  IGAWA K., HORIE K., YUSA K., YOKOZEKI H., KATAYAMA I., TAKEDA. J.
- Organizer
  Implication for therapeutic application. International Investigative Dermatology.
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-25461665
[Presentation] induced keratinocytes from transgene-free but not transgene-residual human induced pluripotent stem cells phenotypically resemble primary human keratinocytes.2012
- Author(s)
  Ken IGAWA, Kyoji HORIE, Hiroo YOKOZEKI, Ichiro KATAYAMA, Junji TAKEDA.
- Organizer
  The 42nd Annual Meeting of the European Society for Dermatological Research
- Place of Presentation
  Venice, Italy
- Data Source
  KAKENHI-PROJECT-24591651
[Presentation] A trial of in vitro reconstitution of human skin using transgene-free induced pluripotent stem cells.2012
- Author(s)
  Ken IGAWA, Kyoji HORIE, Kosuke YUSA, Junji TAKEDA, Ichiro KATAYAMA
- Organizer
  10th annual meeting of ISSCR
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-24591651
[Presentation] 重症アトピー性皮膚炎の新規治療2010
- Author(s)
  井川健
- Organizer
  第109回日本皮膚科学会総会教育講演
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-21791064
[Presentation] 重症アトピー性皮膚炎の新規治療2010
- Author(s)
  井川健
- Organizer
  第109回日本皮膚科学会総会教育講演
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21791064
[Presentation] A therapeutic effect of STAT6 inhibition in atopic dermatitis2009
- Author(s)
  Ken Igawa
- Organizer
  Yonsei Cutaneous Biology Research Institute International Symposium 2009
- Place of Presentation
  Seoul, South Korea
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-21791064
[Presentation] A therapeutic effect of ST AT6 inhibition in atopic dermatitis.2009
- Author(s)
  Igawa K
- Organizer
  Yonsei Cutaneous Biology Research Institute International Symposium 2009
- Place of Presentation
  Seoul(招待講演)
- Data Source
  KAKENHI-PROJECT-21791064

1. Yokozeki Hiroo (90210608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. SATO HITOMI (00648090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HIGUCHI Tetsuya (00334425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TSUBATA Takeshi (80197756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Yoshimura Yasuhide (60263307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 宇賀神つかさ (40581327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 林周次郎 (00599871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 堀江恭二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 山内香織

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 竹田潤二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Igawa Ken 井川 健

井川 健 イガワ ケン

IGAWA Ken 井川 健

Research Projects

Research Products

Co-Researchers

アトピー性皮膚炎におけるMAIT細胞の役割を明らかにするPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ガドリニウム刺激による皮膚線維芽細胞のリプログラミングの可能性

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Examination of 'true' meanings of filaggrin mutation in human epidermal keratinocytes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of cutaneous lesion in collagen disease induced by intranuclear autoantibody.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishments of the new forward genetic method using homologues recombination in human iPS cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An establishment of novel treatment based for the pathogenesis of untreated allergic skin diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

induction from fibroblast to keratinocyte

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A trial for the clarification of the precise relationship between filaggrin gene mutation and atopic dermatitis by using human pluripotent stem cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Approaches of the new therapy development for atopic dermatitis by using RNA interferencePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アトピー性皮膚炎由来の表皮角化細胞における転写調節因子の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Removal of reprogramming transgenes improves the tissue reconstitution potential of keratinocytes generated from human induced pluripotent stem cells.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene silencing of STAT6 with siRNA ameliorates contact hyper sensitivity and allergic rhinitis.2011

Author(s)

Journal Title

Data Source

[Journal Article] Gene silencing of STAT6 with siRNA ameliorates contact hypersensitivity and allergic rhinitis.2011

Author(s)

Journal Title

Data Source

[Journal Article] 【アトピー性皮膚炎の正しい治療】アトピー性皮膚炎の新しい治療の展望2010

Igawa Ken 井川健

井川健イガワケン

IGAWA Ken 井川健

[Presentation] アトピー性皮膚炎の病型と難治性皮膚病変の関連に関する疫学調査2014