OKADA Toshiaki 岡田俊昭

Researcher Number	00373283
Other IDs
Affiliation (based on the past Project Information) *help	2019: 生理学研究所, 生体機能調節研究領域, 研究員 2016 – 2018: 生理学研究所, 生体機能調節研究領域, 特任准教授 2014 – 2016: 生理学研究所, 大学共同利用機関等の部局等, 准教授 2015: 生理学研究所, 細胞器官研究系, 特任准教授 2014: 生理学研究所, 細胞器官研究系, 准教授 2010 – 2013: 生理学研究所, 細胞器官研究系, 特任准教授
Review Section/Research Field	Principal Investigator General physiology Except Principal Investigator General physiology / Biomedical structure and function and related fields / Biological Sciences
Keywords	Principal Investigator 生理学 / イオンチャネル / 分子同定 / ATP release / anion channel / ATP放出 / Maxi-Cl / アニオンチャネル / 分子クローニング / 電気生理 … More Except Principal Investigator … More アニオンチャネル / ATP放出 / 生理学 / 細胞容積調節 / ABCF2 / TRPM7 / S100A10 / アネキシンA2 / SLCO2A1 / Maxi-Cl / 細胞生理学 / タンパク質－タンパク質相互作用 / アニオンチャンネル / 左心室発生圧 / 虚血・再灌流 / 心臓 / 細胞死 / 虚血性細胞死 / ネクローシス / アポトーシス / 酸感受性アニオンチャネル / マキシアニオンチャネル / 容積感受性アニオンチャネル / 分子連関 / ROSセンサー / 容積センサー / メカノセンサー / 蛋白-蛋白相互作用 / モーダルシフト / カチオンチャネル Less

Molecular ON-OFF mechanisms of ATP-releasing maxi-anion channel opening
- Principal Investigator
  
  Okada Yasunobu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomedical structure and function and related fields
- Research Institution
  National Institute for Physiological Sciences
analyses of molecules which are related to an ATP releasing anion channel, Maxi-Cl.Principal Investigator
- Principal Investigator
  
  Okada Toshiaki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  National Institute for Physiological Sciences
Mechanisms of interaction between the volume-sensitive outwardly rectifying anion channel, VSOR, and a novel membrane protein, LRRC8A.
- Principal Investigator
  
  OKADA Yasunobu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  The Graduate University for Advanced Studies
Molecular identification of the ATP-release Maxi-Cl channel and its roles in ischemia-reperfusion cardiac injury
- Principal Investigator
  
  Okada Yasunobu
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  National Institute for Physiological Sciences
  The Graduate University for Advanced Studies
Molecular physiological studies on functional differences among isoforms of ClC-3Principal Investigator
- Principal Investigator
  
  Okada Toshiaki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  National Institute for Physiological Sciences
Molecular characterization of volume-activated anion channels and elucidation of cell death-survival switching mechanisms
- Principal Investigator
  
  OKADA Yasunobu
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General physiology
- Research Institution
  National Institute for Physiological Sciences
Volume-sensor anion channel and mechano-sensor cation channel: Their functional modal shifts and molecular interaction
- Principal Investigator
  
  OKADA Yasunobu
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Physiological Sciences

[Book] “ギャノング　生理学”（原書24版）2014
- Author(s)
  岡田泰伸（監訳者）
- Total Pages
  838
- Publisher
  丸善、東京
- Data Source
  KAKENHI-PROJECT-26293045
[Book] Patch Clamp Techniques - From Beginning to Advanced Protocols2012
- Author(s)
  岡田泰伸 (ed.)
- Total Pages
  439
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-21249010
[Book] 最新パッチクランプ実験技術法2011
- Author(s)
  岡田泰伸 (編著)
- Total Pages
  274
- Publisher
  吉岡書店
- Data Source
  KAKENHI-PROJECT-21249010
[Book] 最新パッチクランプ実験技術法2011
- Author(s)
  岡田泰伸（編著）
- Total Pages
  274
- Publisher
  吉岡書店, 京都
- Data Source
  KAKENHI-PLANNED-18077008
[Book] 最新パッチクランプ実験技術法2011
- Author(s)
  岡田泰伸(編著)
- Total Pages
  274
- Publisher
  吉岡書店
- Data Source
  KAKENHI-PLANNED-18077008
[Book] The puzzles of volume-activated anion channels. In, “Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. From Molecules to Diseases” (eds Alvarez-Leefmans FJ, Delpire E)2009
- Author(s)
  Okada Y, Sato K, Toychiev AH, Suzuki M, Dutta AK, Inoue H, Sabirov RZ.
- Publisher
  Elsevier, San Diego
- Data Source
  KAKENHI-PLANNED-18077008
[Book] Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. From Molecules to Diseases2009
- Author(s)
  Yasunobu Okada
- Publisher
  Elsevier
- Data Source
  KAKENHI-PLANNED-18077008
[Book] Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. From Molecules to Diseases2009
- Author(s)
  岡田泰伸, 他
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-21249010
[Book] Cell volume-sensitive chloride channel: Phenotypic properties and molecular identity. In, “Mechanisms and Significance of Cell Volume Regulation”, (ed. Lang, F.)2006
- Author(s)
  Okada Y.
- Publisher
  Karger, Basel
- Data Source
  KAKENHI-PLANNED-18077008
[Book] Cell volume-sensitive chloride channel : Phenotypic properties and molecular identity. In, "Mechanisms and Significance of Cell Volume Regulation" (ed. F. Lang)2006
- Author(s)
  Y.Okada
- Total Pages
  16
- Publisher
  Karger
- Data Source
  KAKENHI-PLANNED-18077008
[Book] Cell volume-sensitive chloride channel: Phenotypic properties and molecular identity. In, "Mechanisms and Significance of Cell Volume Regulation"2006
- Author(s)
  Y. Okada
- Publisher
  Karger, Basel (ed. F. Lang)
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform.2020
- Author(s)
  R. Nakamura, T. Numata, G. Kasuya, T. Yokoyama, T. Nishizawa, T. Kusakizako, T. Kato, T. Hagino, N. Dohmae, M. Inoue, K. Watanabe, H. Ichijo, M. Kikkawa, M. Shirouzu, T.J. Jentsch, R. Ishitani, Y. Okada, O. Nureki
- Journal Title
  
  Communication Biology
  
  Volume: -
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19517
[Journal Article] Annexin A2-S100A10 Represents the Regulatory Component of Maxi-Cl Channel Dependent on Protein Tyrosine Dephosphorylation and Intracellular Ca2+2020
- Author(s)
  Md. Rafiqul Islam, Toshiaki Okada, Petr G. Merzlyak, Abduqodir H. Toychiev, Yuhko Ando-Akatsuka, Ravshan Z. Sabirov, and Yasunobu Okada
- Journal Title
  
  Cell. Physiol. Biochem.
  
  Volume: 54 Pages: 538-555
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08510
[Journal Article] Cell Volume-Activated and -Correlated Anion Channels in Mammalian Cells: Their Biophysical, Molecular and Pharmacological Properties.2019
- Author(s)
  Y. Okada, T. Okada, K.S. Numata, M.R. Islam, Y.A. Akatsuka, T. Numata, M. Kubo, T. Shimizu, R.S. Kurbannazarova, Y. Marunaka, and R.Z. Sabirov
- Journal Title
  
  Pharmacological Reviews
  
  Volume: 71 Issue: 1 Pages: 49-88
- DOI
  10.1124/pr.118.015917
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08510, KAKENHI-PROJECT-17K08554, KAKENHI-PROJECT-18H03182, KAKENHI-PROJECT-18J40103, KAKENHI-PROJECT-16K08490, KAKENHI-PROJECT-18K06864
[Journal Article] TRPM7 is involved in acid-induced necrotic cell death in a manner sensitive to progesterone in human cervical cancer cells2019
- Author(s)
  Numata Tomohiro、Sato-Numata Kaori、Okada Yasunobu
- Journal Title
  
  Physiological Reports
  
  Volume: 7 Issue: 13
- DOI
  10.14814/phy2.14157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06864, KAKENHI-PROJECT-18J40103, KAKENHI-PROJECT-17K08554, KAKENHI-PROJECT-17K19517
[Journal Article] Herbal components of Japanese Kampo medicines exert laxative actions in colonic epithelium cells via activation of BK and CFTR channels2019
- Author(s)
  Numata Tomohiro、Sato-Numata Kaori、Okada Yasunobu
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 15554-15554
- DOI
  10.1038/s41598-019-52171-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06864, KAKENHI-PROJECT-18J40103, KAKENHI-PROJECT-17K08554, KAKENHI-PROJECT-17K19517
[Journal Article] Molecular identities and ATP release activities of two types of volume-regulatory anion channels, VSOR and Maxi-Cl.2018
- Author(s)
  Y. Okada, T. Okada, M.R. Islam and R.Z. Sabirov
- Journal Title
  
  Curr. Top. Membr.
  
  Volume: 81 Pages: 125-176
- DOI
  10.1016/bs.ctm.2018.07.004
- ISBN
  9780128154564
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08510, KAKENHI-PROJECT-17K19517
[Journal Article] Cellular mechanism for herbal medicine Junchoto to facilitate intestinal Cl-/water secretion that involves cAMP-dependent activation of CFTR2018
- Author(s)
  Tomohiro Numata, Kaori Sato-Numata, Yasunobu Okada, Ryuji Inoue
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 印刷中 Issue: 3 Pages: 694-705
- DOI
  10.1007/s11418-018-1207-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08554, KAKENHI-PROJECT-15J40001, KAKENHI-PROJECT-15K08197, KAKENHI-PROJECT-26860153, KAKENHI-PROJECT-18K06864, KAKENHI-PROJECT-17K19517
[Journal Article] Distinct contributions of LRRC8A and its paralogs to the VSOR anion channel from those of the ASOR anion channel2017
- Author(s)
  Kaori Sato-Numata, Tomohiro Numata, Ryuji Inoue, Ravshan Z. Sabirov and Yasunobu Okada.
- Journal Title
  
  Channels
  
  Volume: 11(2) Issue: 2 Pages: 167-172
- DOI
  10.1080/19336950.2016.1230574
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04678, KAKENHI-PROJECT-15J40001, KAKENHI-PROJECT-15K15028, KAKENHI-PROJECT-15K08197, KAKENHI-PROJECT-26860153, KAKENHI-PROJECT-17K19517, KAKENHI-PROJECT-26293045
[Journal Article] Specific and essential but not sufficient roles of LRRC8A in the activity of volume-sensitive outwardly rectifying anion channel (VOSR).2017
- Author(s)
  T. Okada, Md.R. Islam, N.A. Tsiferova, Y. Okada & R.Z. Sabirov
- Journal Title
  
  Channels (Austin)
  
  Volume: 11 Issue: 2 Pages: 109-120
- DOI
  10.1080/19336950.2016.1247133
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15028, KAKENHI-PROJECT-17K19517, KAKENHI-PROJECT-26293045
[Journal Article] The organic anion transporter SLCO2A1 constitutes the core component of the Maxi-Cl channel.2017
- Author(s)
  Ravshan Z. Sabirov, Petr.G. Merzlyak, Toshiaki Okada, Md. Rafiqul Islam, Hiromi Uramoto, Tomoko Mori, Yumiko Makino, Hiroshi Matsuura, Yu Xie & Yasunobu. Okada
- Journal Title
  
  The EMBO J.
  
  Volume: 36 Issue: 22 Pages: 3309-3324
- DOI
  10.15252/embj.201796685
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08510, KAKENHI-PROJECT-17K08536, KAKENHI-PROJECT-17K19517, KAKENHI-PROJECT-26293045
[Journal Article] Channeling frozen cells to survival after thawing: opening the door to cryo-physiology.2016
- Author(s)
  Y. Okada
- Journal Title
  
  J. Physiol. (London)
  
  Volume: 594 Issue: 6 Pages: 1523-1524
- DOI
  10.1113/jp271842
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15028, KAKENHI-PROJECT-26293045
[Journal Article] The properties, functions and pathophysiology of maxi-anion channels2016
- Author(s)
  Sabirov　RZ, Merzlyak PG, Islam Md R, Okada T & Okada Y
- Journal Title
  
  Pflugers Arch. Eur. J. Physiol.
  
  Volume: 468 Issue: 3 Pages: 405-420
- DOI
  10.1007/s00424-015-1774-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-13F03403, KAKENHI-PROJECT-26293045
[Journal Article] Biophysics and physiology of the volume-regulated anion channel (VRAC)/volume-sensitive outwardly rectifying anion channel (VSOR).2016
- Author(s)
  S.F. Pedersen, Y. Okada & B. Nilius
- Journal Title
  
  Pflugers Arch. Eur. J. Physiol.
  
  Volume: 468 Issue: 3 Pages: 371-383
- DOI
  10.1007/s00424-015-1781-6
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15028, KAKENHI-PROJECT-26293045
[Journal Article] OPINION：バックグラウンドからフォアフロントへ：細胞生死と生体恒常性に関わるセンサーチャネル（後編その３）2015
- Author(s)
  岡田泰伸
- Journal Title
  
  日本生理学雑誌
  
  Volume: 77 Pages: 15-18
- Data Source
  KAKENHI-PROJECT-26293045
[Journal Article] A newly cloned ClC-3 isoform, ClC-3d, as well as ClC-3a mediates Cd^<2+>-sensitive outwardly rectifying anion currents.2014
- Author(s)
  岡田俊昭、秋田天平、佐藤(沼田)かお理、Md. Rafiqul Islam、岡田泰伸
- Journal Title
  
  Cellular Physiology and Biochemistry
  
  Volume: 33 Issue: 3 Pages: 539-556
- DOI
  10.1159/000358633
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13F03403, KAKENHI-PROJECT-23612008, KAKENHI-PROJECT-24590291, KAKENHI-PROJECT-25670112, KAKENHI-PROJECT-26293045
[Journal Article] Temperature sensitivity of acid-sensitive outwardly rectifying (ASOR) anion channels in cortical neurons is involved in hypothermic neuroprotection against acidotoxic necrosis.2014
- Author(s)
  K. Sato-Numata, T. Numata & Y. Okada
- Journal Title
  
  Channels
  
  Volume: 8 Pages: 1-6
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293045
[Journal Article] Characteristics and roles of the volume-sensitive outwardly rectifying (VSOR) anion channel in the central nervous system.2014
- Author(s)
  T. Akita & Y. Okada
- Journal Title
  
  Neuroscience
  
  Volume: 275 Pages: 211-231
- DOI
  10.1016/j.neuroscience.2014.06.015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670112, KAKENHI-PROJECT-26293045, KAKENHI-PROJECT-26460293
[Journal Article] A newly cloned ClC-3 isoform, ClC-3d, as well as ClC-3a mediates Cd^<2+>-sensitive outwardly rectifying anion currents2014
- Author(s)
  T. Okada, T. Akita, K. Sato-Numata, M.R. Islam, Y. Okada
- Journal Title
  
  Cellular Physiology and Biochemistry
  
  Volume: 33 Pages: 539-556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] 生から死へ、死から生への生理学－統合科学序説－2014
- Author(s)
  岡田泰伸
- Journal Title
  
  総合研究大学院大学葉山彙報
  
  Volume: 5 Pages: 31-51
- Data Source
  KAKENHI-PROJECT-26293045
[Journal Article] TMEM16F is a component of a Ca2+-activated Cl- channel but not a volume-sensitive outwardly rectifying Cl- channel.2013
- Author(s)
  清水貴浩、家原貴大、佐藤かお理、藤井拓人、酒井秀紀、岡田泰伸
- Journal Title
  
  American Journal of Physiology. Cell Physiology
  
  Volume: 304 Issue: 8 Pages: C748-C759
- DOI
  10.1152/ajpcell.00228.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010, KAKENHI-PROJECT-24659095, KAKENHI-PROJECT-24790209, KAKENHI-PROJECT-25293047, KAKENHI-PROJECT-25460282
[Journal Article] TMEM16F is a component of a Ca^<2+>-activated Cl^-channel but not a volume-sensitive outwardly rectifying C^-channel2013
- Author(s)
  T. Shimizu, T. Iehara, K. Sato, T. Fujii, H. Sakai, Y. Okada
- Journal Title
  
  American Journal of Physiology - Cell Physiology
  
  Volume: 304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] 細胞死のチャネルメカニズムとその病態2013
- Author(s)
  岡田泰伸
- Journal Title
  
  日本病態生理学会雑誌
  
  Volume: 21 Pages: 14-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells.2012
- Author(s)
  Islam M.R.、浦本裕美、岡田俊昭、Sabirov R.Z.、岡田泰伸
- Journal Title
  
  American Journal of Physiology. Cell Physiology
  
  Volume: 303 Issue: 9 Pages: C924-C935
- DOI
  10.1152/ajpcell.00459.2011
- NAID
  120005325299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Apoptotic volume decrease (AVD) is independent of mitochondrial dysfunction and initiator caspase activation.2012
- Author(s)
  前野恵美、鍔田武志、岡田泰伸
- Journal Title
  
  Cells
  
  Volume: 1 Issue: 4 Pages: 1156-1167
- DOI
  10.3390/cells1041156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010, KAKENHI-PROJECT-23390063
[Journal Article] Involvements of the ABC protein ABCF2 and α-actinin-4 in regulation of cell volume and anion channels in human epithelial cells.2012
- Author(s)
  Ando-Akatsuka Y, Shimizu T, Numata T, Okada Y.
- Journal Title
  
  J Cell Physiol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Apoptotic volume decrease (AVD) is independent of mitochondrial dysfunction and initiator caspase activation2012
- Author(s)
  E. Maeno, T. Tsubata, Y. Okada
- Journal Title
  
  Cells
  
  Volume: 1 Pages: 1156-1167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Involvements of the ABC protein ABCF2 and α-actinin-4 in regulation of cell volume and anion channels in human epithelial cells2012
- Author(s)
  Y Ando-Akatsuka, T Shimizu, T Numata, Y Okada
- Journal Title
  
  J Cell Physiol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Early-phase occurrence of K+ and Cl- efflux in addition to Ca2+ mobilization is a prerequisite to apoptosis in HeLa cells.2012
- Author(s)
  出崎克也、前野恵美、佐藤かお理、秋田天平、岡田泰伸
- Journal Title
  
  Apoptosis
  
  Volume: 17 Issue: 8 Pages: 821-831
- DOI
  10.1007/s10495-012-0716-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010, KAKENHI-PROJECT-23591320, KAKENHI-PROJECT-23612008
[Journal Article] The apoptotic volume decrease is an upstream event of MAP kinase activation during staurosporine-induced apoptosis in HeLa cells.2012
- Author(s)
  長谷川裕一、清水貴浩、高橋信之、岡田泰伸
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 13 Issue: 7 Pages: 9363-9379
- DOI
  10.3390/ijms13079363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010, KAKENHI-PROJECT-22590201
[Journal Article] Involvements of the ABC protein ABCF2 and α-actinin-4 in regulation of cell volume and anion channels in human epithelial cells2012
- Author(s)
  Y. Ando-Akatsuka, T. Shimizu, T. Numata, Y. Okada
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 227 Pages: 3498-3510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells2012
- Author(s)
  M.R. Islam, H. Uramoto, T. Okada, R.Z. Sabirov, Y. Okada
- Journal Title
  
  American Journal of Physiology - Cell Physiology
  
  Volume: 303
- NAID
  120005325299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] The apoptotic volume decrease is an upstream event of MAP kinase activation during staurosporine-induced apoptosis in HeLa cells2012
- Author(s)
  Y. Hasegawa, T. Shimizu, N. Takahashi, Y. Okada
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 13 Pages: 9363-9379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Protective role of cardiac CFTR activation upon early reperfusion against myocardial infarction2012
- Author(s)
  H. Uramoto, T. Okada, Y. Okada
- Journal Title
  
  Cellular Physiology and Biochemistry
  
  Volume: 30 Pages: 1023-1038
- NAID
  120005325298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Early-phase occurrence of K+ and Cl^- efflux in addition to Ca^<2+> mobilization is a prerequisite to apoptosis in HeLa cells2012
- Author(s)
  K. Dezaki, E. Maeno, K. Sato, T. Akita, Y. Okada
- Journal Title
  
  Apoptosis
  
  Volume: 17 Pages: 821-831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Protective role of cardiac CFTR activation upon early reperfusion against myocardial infarction.2012
- Author(s)
  浦本裕美、岡田俊昭、岡田泰伸
- Journal Title
  
  Cellular Physiology and Biochemistry
  
  Volume: 30 Issue: 4 Pages: 1023-1038
- DOI
  10.1159/000341479
- NAID
  120005325298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] V_2 receptor-mediated autocrine role of somatodendritic release of AVP in ratvasopressin neurons under hypo-osmotic conditions2011
- Author(s)
  S Kaori, T Numata, T Saito, Y Ueta, Y Okada
- Journal Title
  
  Sci Signal
  
  Volume: 4
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Swelling-activated anion channels are essential for volume regulation of mouse thymocytes2011
- Author(s)
  RS Kurbannazarova, SV Bessonova, Y Okada, RZ Sabirov
- Journal Title
  
  Int J Mol Sci
  
  Volume: 12 Pages: 9125-9137
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying anion channels by Ca^<2+> nanodomains in mouse astrocytes.2011
- Author(s)
  Akita T, Okada Y.
- Journal Title
  
  J Physiol
  
  Volume: 589 Pages: 3909-3927
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Swelling-activated anion channels are essential for volume regulation of mouse thymocytes.2011
- Author(s)
  Kurbannazarova RS, Bessonova SV, Okada Y, Sabirov RZ.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 12 Pages: 9125-9137
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Ca^<2+> nanodomain-mediated component of swelling-induced volume-sensitive outwardly rectifying anion current triggered by autocrine action of ATP in mouse astrocytes2011
- Author(s)
  T. Akita, S.V. Fedorovich, Y. Okada
- Journal Title
  
  Cellular Physiology and Biochemistry
  
  Volume: 28 Pages: 1181-1190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] V_2 receptor-mediated autocrine role of somatodendritic release of AVP in rat vasopressin neurons under hypo-osmotic conditions2011
- Author(s)
  K. Sato, T. Numata, T. Saito, Y. Ueta, Y. Okada
- Journal Title
  
  Science Signaling
  
  Volume: 4(157)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying anion channels by Ca^<2+> nanodomains in mouse astrocytes2011
- Author(s)
  T. Akita, Y. Okada
- Journal Title
  
  Journal of Physiology (London)
  
  Volume: 589 Pages: 3909-3927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying anion channels by Ca^<2+> nanodomains in mouse astrocytes2011
- Author(s)
  T Akita, Y Okada
- Journal Title
  
  J Physiol
  
  Volume: 589 Pages: 3909-3927
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] V_2 receptor-mediated autocrine role of somatodendritic release of AVP in rat vasopressin neurons under hypo-osmotic conditions.2011
- Author(s)
  Sato K, Numata T, Saito T, Ueta Y, Okada Y.
- Journal Title
  
  Sci Signal
  
  Volume: 4 (157), ra5
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Clustering of protein kinase A-dependent CFTR chloride channels in the sarcolemma of guinea-pig ventricular myocytes.2010
- Author(s)
  A.F.James, R.Z Sabirov, Y.Okada
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 391 Pages: 841-845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Acid-sensing ion channels in rat hypothalamic vasopressin neurons of the supraoptic nucleus.2010
- Author(s)
  Ohbuchi T, Sato K, Suzuki H, Okada Y, Dayanithi G, Murphy D, Ueta Y.
- Journal Title
  
  J Physiol
  
  Volume: 588 Pages: 2147-62
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Inhibition of a protein kinase Akt1 by apoptosis signal-regulating kinase-1 (ASK1) is involved in apoptotic inhibition of regulatory volume increase2010
- Author(s)
  M. Subramanyam, N. Takahashi, Y. Hasegawa, T. Mohri, Y. Okada
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 285 Pages: 6109-6117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Activation of the maxi-anion channel by protein tyrosine dephosphorylation2010
- Author(s)
  AH Toychiev, RZ Sabirov, N Takahashi, Y Ando-Akatsuka, H-T Liu, T Shintani, M Noda, Y Okada
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 297
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Inhibition of a protein kinase Akt1 by apoptosis signal-regulating kinase-1(ASK1)is involved in apoptotic inhibition of regulatory volume increase.2010
- Author(s)
  M.Subramanyam, N.Takahashi, Y.Hasegawa, T.Mohri, Y.Okada
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 6109-6117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Volume-sensitive outwardly rectifying chloride channel in white adipocytes from normal and diabetic mice.2010
- Author(s)
  Inoue H, Takahashi N, Okada Y, Konishi M.
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 298
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Volume-sensitive outwardly rectifying chloride channel in white adipocytes from normal and diabetic mice.2010
- Author(s)
  H.Inoue, N.Takahashi, Y.Okada, M.Konishi
- Journal Title
  
  Am.J.Physiol.Cell Physiol.
  
  Volume: 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Acid-sensing ion channels in rat hypothalamic vasopressin neurons of the supraoptic nucleus2010
- Author(s)
  T Ohbuchi, K Sato, H Suzuki, Y Okada, G Dayanithi, D Murphy, Y Ueta
- Journal Title
  
  J Physiol
  
  Volume: 588 Pages: 2147-2162
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Volume-sensitive outwardly rectifying chloride channel in white adipocytes from normal and diabetic mice2010
- Author(s)
  H Inoue, N Takahashi, Y Okada, M Konishi
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 298
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Inhibition of a protein kinase Akt1 by apoptosis signal-regulating kinase-1 (ASK1) is involved in apoptotic inhibition of regulatory volume increase2010
- Author(s)
  M Subramanyam, N Takahashi, Y Hasegawa, T Mohri, Y Okada
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 6109-6117
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Clustering of protein kinase A-dependent CFTR chloride channels in the sarcolemma of guinea-pig ventricular myocytes2010
- Author(s)
  AF James, RZ Sabirov, Y Okada
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 391 Pages: 841-845
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Bradykinin-induced astrocyte-neuron signaling: glutamate release is mediated by ROS-activated volume-sensitive outwardly rectifying anion channels.2009
- Author(s)
  Liu H-T, Akita T, Shimizu T, Sabirov RZ, Okada Y.
- Journal Title
  
  J Physiol
  
  Volume: 587 Pages: 2197-209
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel2009
- Author(s)
  Yasunobu Okada
- Journal Title
  
  Journal of Physiology(London) 587
  
  Pages: 2141-2149
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Bradykinin-induced astrocyte-neuron signaling : glutamate release is mediated by ROS-activated volume-sensitive outwardly rectifying anion channels2009
- Author(s)
  H.-T. Liu, T. Akita, T. Shimizu, R.Z. Sabirov, Y. Okada
- Journal Title
  
  Journal of Physiology (London)
  
  Volume: 587 Pages: 2197-2209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article]2009
- Author(s)
  Yasunobu Okada
- Journal Title
  
  Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. From Molecules to Diseases(Elsevier)
  
  Pages: 283-306
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel.2009
- Author(s)
  Okada Y, Sato K, Numata T.
- Journal Title
  
  J Physiol
  
  Volume: 587 Pages: 2141-9
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel2009
- Author(s)
  Yasunobu Okada
- Journal Title
  
  Journal of Physiology (London) (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel2009
- Author(s)
  Y. Okada, K. Sato, T. Numata
- Journal Title
  
  Journal of Physiology (London)
  
  Volume: 587 Pages: 2141-2149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Bradykinin-induced astrocyte-neuron signaling: glutamate release is mediated by ROS-activated volume-sensitive outwardly rectifying anion channels2009
- Author(s)
  H.-T. Liu, T. Akita, T. Shimizu, R.Z. Sabirov & Y. Okada
- Journal Title
  
  J. Physiol. (London) 587
  
  Pages: 2197-2209
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Activation of the maxi-anion channel by protein tyrosine dephosphorylation2009
- Author(s)
  A.H. Toychiev, R.Z. Sabirov, N. Takahashi, Y. Ando-Akatsuka, H.-T. Liu, T. Shintani, M. Noda, Y. Okada
- Journal Title
  
  American Journal of Physiology - Cell Physiology
  
  Volume: 297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel2009
- Author(s)
  Yasunobu Okada
- Journal Title
  
  Journal of Physiology(London) 587
  
  Pages: 2141-2149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249010
[Journal Article] Molecular determinants of sensitivity and conductivity of human TRPM7 to Mg2+ and Ca2+2008
- Author(s)
  T. Numata & Y. Okada
- Journal Title
  
  Channels 2
  
  Pages: 283-286
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Proton conductivity through the human TRPM7 channel and its molecular determinants.2008
- Author(s)
  Numata T, Okada Y
- Journal Title
  
  J Biol Chem
  
  Volume: 283 Pages: 15097-15103
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Proton conductivity through the human TRPM7 channel and its molecular determinants2008
- Author(s)
  T. Numata & Y. Okada
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 15097-15103
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Molecular determinants of sensitivity and conductivity of human TRPM7 to Mg^<2+> and Ca^<2+>.2008
- Author(s)
  Numata T , Okada Y
- Journal Title
  
  Channels
  
  Volume: 2 Pages: 283-286
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] TRPM7 is a stretch- and swelling-activated cation channel involvedin volume regulation in human epithelial cells2007
- Author(s)
  T. Numata, T. Shimizu & Y. Okada
- Journal Title
  
  Am. J. Physiol. Cell Physiol 292
  
  Pages: 460-467
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] TRPM7 is a stretch- and swelling-activated cation channel involved in volume regulation in human epithelial cells.2007
- Author(s)
  Numata T, Shimizu T, Okada Y.
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 292
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Journal Article] Direct mechano-stress sensitivity of TRPM7 channel.2007
- Author(s)
  Numata T, Shimizu T, Okada Y.
- Journal Title
  
  Cell Physiol Biochem
  
  Volume: 19 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Appropriate combinations of herbal components of Japanese Kampo medicines exert laxative actions in colonic epithelium cells through activation of K and Cl channels.2020
- Author(s)
  T Numata, K Sato-Numata, Y Okada, R Inoue
- Organizer
  第97回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K19517
[Presentation] Effect of ATP released from the maxi-anion channel on left ventricular contractile function in Langendorff-perfused mouse heart model.2020
- Author(s)
  H Matsuura, A Kojima, Y Fukushima, Y Xie, X Mi, RZ Sabirov, Y Okada
- Organizer
  第97回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K19517
[Presentation] Ni+-sensitive Ca2+ channels are involved in the exocytotic secretion from somata/dendrites in vasopressin neurons.2020
- Author(s)
  K Sato-Numata, T Numata, Y Ueta, Y Okada
- Organizer
  第97回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K19517
[Presentation] Reexamination of the roles of LRRC8 and TTYH in the molecular identity of volume-sensitive outwardly rectifying anion channel VSOR.2020
- Author(s)
  Y Okada, T Okada, K Sato-Numata, T Numata
- Organizer
  第97回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K19517
[Presentation] Sensitivity of voltage-dependent Ca2+ channels in rat AVP neurons to an anthranilic acid derivative.2019
- Author(s)
  Sato K, Numata T, Ueta U, Okada Y
- Organizer
  9th Congress of the Federation of The Asia and Oceanian Physiological Societies (FAOPS 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19517
[Presentation] A calcium-binding protein S100A10 is a regulator of Maxi-Cl channel activity.2019
- Author(s)
  Islam Md R, Okada T, Toychiev A, Sabirob RZ, Okada Y
- Organizer
  9th Congress of the Federation of The Asia and Oceanian Physiological Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19517
[Presentation] Examination of the contribution of SLCO2A1 to maxi-anion channel currents in murine cells2019
- Author(s)
  Toshiaki Okada　and Yasunobu Okada
- Organizer
  第9回アジア・オセアニア生理学会連合(FAOPS)大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08510
[Presentation] Kampo medicine Junchoto promotes intestinal Cl-/water secretion by cAMP-dependent CFTR activation.2019
- Author(s)
  Numata T, Sato-Numata K, Okada Y, Inoue R
- Organizer
  9th Congress of the Federation of The Asia and Oceanian Physiological Societies (FAOPS 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19517
[Presentation] A calcium-binding protein S100A10 is a regulator of Maxi-Cl channel activity.2019
- Author(s)
  Islam Md R, Okada T, Toychiev A, Sabirob RZ, Okada Y
- Organizer
  9th Congress of the Federation of The Asia and Oceanian Physiological Societies (FAOPS 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19517
[Presentation] Examination of the contribution of SLCO2A1 to maxi-anion channel currents in murine cells.2019
- Author(s)
  Okada T, Okada Y
- Organizer
  9th Congress of the Federation of The Asia and Oceanian Physiological Societies (FAOPS 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19517
[Presentation] SLCO2A1 is a pore-forming component of Maxi-Cl channel.2018
- Author(s)
  Okada T, Islam Md R, Merzlyak GP, Sabirov RZ, Okada Y
- Organizer
  第95回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K19517
[Presentation] Properties and roles of flufenamate-sensitive ion channels stimulated by hyperosmolality in vasopressin neurons.2018
- Author(s)
  Sato-Numata K, Numata T, Ueda Y, Inoue R, Okada Y
- Organizer
  第95回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K19517
[Presentation] SLCO2A1 is a pore-forming component of Maxi-Cl channel.2018
- Author(s)
  Okada T, Islam Md R, Merzlyak GP, Sabirov RZ, Okada Y
- Organizer
  第95回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-26293045
[Presentation] SLCO2A1 is a pore-forming component of Maxi-Cl channel2018
- Author(s)
  Toshiaki Okada, Md. Rafiqul Islam, Petr G. Merzlyak, Ravshan Z. Sabirov, Yasunobu Okada
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-16K08510
[Presentation] Properties and roles of flufenamate-sensitive ion channels stimulated by hyperosmolality in vasopressin neurons.2018
- Author(s)
  Sato-Numata K, Numata T, Ueda Y, Inoue R, Okada Y
- Organizer
  第95回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-26293045
[Presentation] SLCO2A1 is involved in a pathway for ATP release from cultured cells and Langendorff-perfused hearts.2018
- Author(s)
  Islam Md R, Okada T, Matsuura H, Uramoto H, Sabirov RZ, Okada Y
- Organizer
  第95回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K19517
[Presentation] SLCO2A1 is involved in a pathway for ATP release from cultured cells and Langendorff-perfused hearts.2018
- Author(s)
  Islam Md R, Okada T, Matsuura H, Uramoto H, Sabirov RZ, Okada Y
- Organizer
  第95回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-26293045
[Presentation] LRRC8 family is involved in volume-sensitive outwardly rectifying anion channel (VSOR) activity but not in acid-sensitive outwardly rectifying anion channel (ASOR) activity.2017
- Author(s)
  Sato-Numata K, Numata T, Inoue R, Sabirov RZ, Okada Y
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K15028
[Presentation] Molecular identification of two types of volume-activated anion channels involved in multiple functions controlling cell life.2017
- Author(s)
  Okada Y, Sabirov RZ, Okada T, Merzlyak PG, Islam Md R, Sato-Numata K, Uramoto H, Ando-Akatsuka Y, Matsuura H
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26293045
[Presentation] Molecular verification for the Maxi-Cl channel molecule as a cellular ATP release pathway.2017
- Author(s)
  Islam Md R, Merzlyak PG, Okada T, Uramoto H, Okada Y, Sabirov RZ
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26293045
[Presentation] Identification of the key molecule of Maxi-Cl channel by proteomics and genome-wide approaches.2017
- Author(s)
  Okada T, Sabirov RZ, Merzlyak PG, Islam Md R, Uramoto H, Mori T, Makino Y, Okada Y
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26293045
[Presentation] Involvements of LRRC8A and amino acid transporter SLC proteins in the activity of volume-sensitive outwardly rectifying anion channel (VSOR).2016
- Author(s)
  Okada T, Sabirov RZ, Ohgaki R, Nagamori S, Kanai Y, Ono K, Uramoto H, Okada Y
- Organizer
  第93回　日本生理学会大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K15028
[Presentation] シスプラチン耐性細胞株KCP-4におけるLRRC8分子群の役割の検討2016
- Author(s)
  岡田俊昭, Md.R. Islam, N.A. Tsiferova, R.S. Kurbannazarova, 岡田泰伸, R.Z. Sabirov
- Organizer
  第63回中部日本生理学会
- Place of Presentation
  岡崎市
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-15K15028
[Presentation] Properties of the maxi-anion channel in melanoma cells.2016
- Author(s)
  Tsiferova NA, Merzlyak PG, Okada Y,Sabirov RZ
- Organizer
  第93回　日本生理学会大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26293045
[Presentation] Pharmacological distinction between acid-sensitive outwardly rectifying anion channel (ASOR) and volume-sensitive outwardly rectifying anion channel (VSOR).2016
- Author(s)
  Sato-Numata K, Numata T, Inoue R, Okada Y
- Organizer
  第93回　日本生理学会大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K15028
[Presentation] Evidence for a modulatory role of annexin A2 in the maxi-anion channel activity.2015
- Author(s)
  Islam Md R, Okada T, Merzlyak P, Sabirov RZ, Okada Y
- Organizer
  第８回アジアオセアニア生理学会大会
- Place of Presentation
  タイ国　バンコック市
- Year and Date
  2015-11-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293045
[Presentation] Analysis of basic electrophysiological properties of a new isoform of ClC-3, ClC-3d.2013
- Author(s)
  Toshiaki Okada, Tenpei Akita and Yasunobu Okada
- Organizer
  大90回日本生理学会大会
- Place of Presentation
  東京都　江戸川区　タワーホール船堀
- Data Source
  KAKENHI-PROJECT-24590291
[Presentation] Roles of volume-regulatory ion channels in cell survival-death switching2012
- Author(s)
  岡田泰伸
- Organizer
  The 3rd Symposium of International Society for Proton Dynamics in Cancer (ISPDC)
- Place of Presentation
  京都府立医科大学、京都
- Year and Date
  2012-10-12
- Data Source
  KAKENHI-PROJECT-21249010
[Presentation] Attempts to identify the gene encoding Maxi-anion channel2012
- Author(s)
  岡田俊昭
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  松本市総合体育館、松本
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21249010
[Presentation] 細胞死のチャネルメカニズムとその病態生理学2012
- Author(s)
  岡田泰伸
- Organizer
  第22回日本病態生理学会
- Place of Presentation
  湯布院厚生年金病院学習棟、大分
- Year and Date
  2012-08-04
- Data Source
  KAKENHI-PROJECT-21249010
[Presentation] Functional coupling between VSOR Cl^- channel and TRPM7 channel in hypotonic condition in DT40 cells. J. Physiol. Sci. 61 (Suppl 1), S1282011
- Author(s)
  Numata T, Sato K, Schmitz C, Hermosura MC, Perraud A-L, Mori Y, Okada Y
- Organizer
  第88回日本生理学会大会
- Place of Presentation
  (誌上発表)
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Volume-regulatory autocrine action of vasopressin released from somato and dendrites in vasopressin neurons is mediated by the V_2 receptor and cAMP. Abstract p162011
- Author(s)
  Sato K, Numata T, Saito T, Ueta Y, Okada Y
- Organizer
  Hydration & Cell Volume Regulation: Cell Volume regulation Meeting 2011
- Place of Presentation
  Tubingen, Germany
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] TRPM7 is an essential regulator for the volume-sensitive outwardly rectifying anion channel (VSOR) activity. Abstract p2402011
- Author(s)
  Numata T, Sato K, Schmitz C, Hermosura MC, Perraud A-L, Mori Y, Okada Y
- Organizer
  7th Congress of the Federation of The Asia and Oceanian Physiological Societies (FAOPS 2011)
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Ca^<2+> nanodomain-mediated regulation of volume-sensitive outwardly rectifying (VSOR) anion channels in mouse astrocytes. Abstract p72011
- Author(s)
  Akita T, Okada Y
- Organizer
  Hydration & Cell Volume Regulation: Cell Volume regulation Meeting 2011
- Place of Presentation
  Tubingen, Germany
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] TRPM7 is an essential regulator for the volume-sensitive outwardly rectifying anion channel (VSOR) activity2010
- Author(s)
  岡田泰伸
- Organizer
  7th Congress of the Federation of The Asia and Oceanian Physiological Societies (FAOPS 2011)
- Place of Presentation
  Taipei (Taiwan)
- Year and Date
  2010-09-13
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Regulation of bradykinin-induced activation of volume-sensitive outwardly rectifying (VSOR) anion channels via “Ca^<2+> nanodomains” in mouse cortical astrocytes. J. Physiol. Sci. 60 (Suppl), S662010
- Author(s)
  Akita T, Okada Y
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール・いわて県民情報交流センター, 盛岡, (シンポジウム口演)
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Inducing and rescuing roles of ion channels in cell death2010
- Author(s)
  岡田泰伸
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  いわて県民情報交流センター盛岡市民文化ホール(岩手)
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Inducing and rescuing roles of ion channels in cell death2010
- Author(s)
  岡田泰伸
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  いわて県民情報交流センター盛岡市民文化ホール、岩手
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-21249010
[Presentation] Inducing and rescuing roles of ion channels in cell death.2010
- Author(s)
  岡田泰伸
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  いわて県民情報交流センター盛岡市民文化ホール(岩手)
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-21249010
[Presentation] Role of the actin cytoskeleton in the interaction between ABCF2 and α-actinin-4. J. Physiol. Sci. 60 (Suppl), S772010
- Author(s)
  Ando-Akatsuka Y, Okada Y
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール・いわて県民情報交流センター, 盛岡
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] The role of vasopressin receptor in the AVP neurons under hypotonic conditions. J. Physiol. Sci. 60 (Suppl), S1222010
- Author(s)
  Sato K, Numata T, Ueta Y, Okada Y
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール・いわて県民情報交流センター, 盛岡
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Reduced expression level of volume-sensitive chloride channel in diabetic adipocytes. J. Physiol. Sci. 60 (Suppl), S1052010
- Author(s)
  Inoue H, Takahashi N, Okada Y, Konishi M
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール・いわて県民情報交流センター, 盛岡
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Roles of anion channels and disordered cell volume regulation in apoptotic and necrotic cell death2009
- Author(s)
  Yasunobu Okada
- Organizer
  International Joint Symposium : Physiology of Anion Transport and Cell Volume Regulation(PAT-CVR 2009)
- Place of Presentation
  岡崎コンファレンスセンター(愛知)
- Year and Date
  2009-08-04
- Data Source
  KAKENHI-PROJECT-21249010
[Presentation] Bradykinin-induced glutamate release via volume-sensitive outwardly rectifying (VSOR) anion channels in mouse cortical astrocytes. J Physiol Sci 59 Suppl 1 p3922009
- Author(s)
  Akita T, Liu H, Sabirov R, Shimizu T, Okada Y
- Organizer
  XXXVI International Congress of Physiological Sciences (IUPS2009)
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Volume-sensitive chloride channel activity in freshly isolated white adipocytes from normal and diabetic mice. J Physiol Sci 59 Suppl 1 p4132009
- Author(s)
  Inoue H, Takahashi N, Okada Y, Konishi M
- Organizer
  XXXVI International Congress of Physiological Sciences (IUPS2009)
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Regulatory role of the interaction between ACTN4 and ABCF2 in cell volume regulation and volume-sensitive anion channel. J Physiol Sci 59 Suppl 1 p3922009
- Author(s)
  Ando-Akatsuka Y, Shimizu T, Numata T, Mori Y, Okada Y
- Organizer
  XXXVI International Congress of Physiological Sciences (IUPS2009)
- Place of Presentation
  Kyoto International Conference Center, Kyoto, Japan
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Roles of anion channels and disordered cell volume regulation in apoptotic and necrotic cell death2009
- Author(s)
  岡田泰伸
- Organizer
  International Joint Symposium : Physiology of Anion Transport and Cell Volume Regulation (PAT- CVR 2009)
- Place of Presentation
  岡崎コンファレンスセンター、愛知
- Year and Date
  2009-08-04
- Data Source
  KAKENHI-PROJECT-21249010
[Presentation] Roles of volume-sensitive anion channels in cell death induction and glia-to-neuron signaling2009
- Author(s)
  Yasunobu Okada
- Organizer
  XXXVI International Congress of Physiological Sciences(IUPS2009)
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Interaction between ABCF2 and α-actinin-4 is involved in activation of the volume-regulatory anion channel. J. Physiol. Sci. 57 (Suppl), S1242007
- Author(s)
  Ando-Akatsuka Y, Shimizu T, Okada Y
- Organizer
  第84回日本生理学会大会
- Place of Presentation
  大阪国際交流センター, 大阪
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Volume-sensitive chloride channel activity in hippocampal and cortical pyramidal neurons in slice preparation. J. Physiol. Sci. 57 (Suppl), S2302007
- Author(s)
  Inoue H, Okada Y
- Organizer
  第84回日本生理学会大会
- Place of Presentation
  大阪国際交流センター, 大阪
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] Bradykinin-induced communication between astrocytes and neurons is mediated by glutamate released via volume-sensitive outwardly rectifying anion channels. J. Physiol. Sci. 57 (Suppl), S1262007
- Author(s)
  Liu H-T, Sabirov Z, Okada Y
- Organizer
  第84回日本生理学会大会
- Place of Presentation
  大阪国際交流センター, 大阪
- Data Source
  KAKENHI-PLANNED-18077008
[Presentation] 細胞死のチャネルメカニズムとその病態生理学
- Author(s)
  岡田泰伸
- Organizer
  第22回　日本病態生理学会　細見記念講演
- Place of Presentation
  湯布院厚生年金病院学習棟（大分県）
- Data Source
  KAKENHI-PROJECT-21249010
[Presentation] Volume-sensitive anion channels in melanoma cells before and after tumor formation.
- Author(s)
  Sabirov RZ, Tsiferova NA, Merzlyak PG, Okada Y
- Organizer
  第92回　日本生理学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-26293045
[Presentation] Exploration of temperature sensitivity and new antagonists of acid-sensitive outwardly rectifying anion channel (ASOR).
- Author(s)
  Sato-Numata K, Numata T, Okada Y
- Organizer
  第92回　日本生理学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-26293045
[Presentation] Roles of volume-regulatory ion channels in cell survival-death switching
- Author(s)
  岡田泰伸
- Organizer
  The 3rd Symposium of International Society for Proton Dynamics in Cancer (ISPDC)
- Place of Presentation
  京都府立医科大学（京都府）
- Data Source
  KAKENHI-PROJECT-21249010
[Presentation] Annexin A2 is a modulator of maxi-anion channel (Maxi-Cl) in mouse mammary C127 cells.
- Author(s)
  Islam Md R, Okada T, Merzlyak PG, Sabirov RZ, Okada Y
- Organizer
  第92回　日本生理学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-26293045
[Presentation] Examination of the role of LRRC8A in the function of volume-sensitive outwardly rectifying anion channel (VSOR).
- Author(s)
  Okada T, Sato-Numata K, Islam Md R, Sabirov RZ, Okada Y
- Organizer
  第92回　日本生理学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-26293045

1. OKADA Yasunobu (10025661)

# of Collaborated Projects: 5 results

# of Collaborated Products: 127 results
2. SATO Kaori (60614196)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
3. AKATSUKA Yuhko (90321611)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
4. NUMATA Tomohiro (20455223)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
5. AKITA Tenpei (00522202)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
6. TAKAHASHI Nobuyuki (50370135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. INOUE Hana (20390700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. LEE Elbert (30425425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHIMIZU Takahiro (40353437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. ONO Koh (00359275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KOIZUMI Amane (10296551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KUKITA Fumio (40113427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. URAMOTO Hiromi (50390696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. 松浦博 (60238962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 井上隆司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. ISLAM Md.rafiqul

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
17. ISLAM Md. Rafiqul

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

OKADA Toshiaki 岡田 俊昭

Research Projects

Research Products

Co-Researchers

Molecular ON-OFF mechanisms of ATP-releasing maxi-anion channel opening

Principal Investigator

Project Period (FY)

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analyses of molecules which are related to an ATP releasing anion channel, Maxi-Cl.Principal Investigator

Principal Investigator

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Research Institution

Mechanisms of interaction between the volume-sensitive outwardly rectifying anion channel, VSOR, and a novel membrane protein, LRRC8A.

Principal Investigator

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Research Category

Research Field

Research Institution

Molecular identification of the ATP-release Maxi-Cl channel and its roles in ischemia-reperfusion cardiac injury

Principal Investigator

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Research Institution

Molecular physiological studies on functional differences among isoforms of ClC-3Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Molecular characterization of volume-activated anion channels and elucidation of cell death-survival switching mechanisms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Volume-sensor anion channel and mechano-sensor cation channel: Their functional modal shifts and molecular interaction

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] “ギャノング 生理学”（原書24版）2014

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[Book] Patch Clamp Techniques - From Beginning to Advanced Protocols2012

Author(s)

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[Book] 最新パッチクランプ実験技術法2011

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[Book] 最新パッチクランプ実験技術法2011

Author(s)

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[Book] 最新パッチクランプ実験技術法2011

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[Book] The puzzles of volume-activated anion channels. In, “Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. From Molecules to Diseases” (eds Alvarez-Leefmans FJ, Delpire E)2009

Author(s)

Publisher

Data Source

[Book] Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. From Molecules to Diseases2009

Author(s)

Publisher

Data Source

[Book] Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. From Molecules to Diseases2009

OKADA Toshiaki 岡田俊昭

[Book] “ギャノング　生理学”（原書24版）2014