Yamamoto Kuniharu 山本久仁治

… Alternative Names

山本久仁治ヤマモトクニハル

YAMAMOTO Kuniharu 山本久仁治

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Researcher Number	00375073
Affiliation (Current)	2025: 東北医科薬科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 東北医科薬科大学, 医学部, 准教授 2014 – 2020: 地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所), がん幹細胞研究部, 特任研究員 2012: 東北大学, 医学(系)研究科(研究院), 非常勤講師 2010 – 2012: 東北大学, 大学院・医学系研究科, 非常勤講師 2010: 東北大学, 病院, 非常勤講師 2009: Tohoku University, 病院, 助教 2006: Tohoku University, Hospital, Research Associate, 病院・助手
Review Section/Research Field	Principal Investigator Digestive surgery / General surgery Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator がん幹細胞 / 胆管癌 / 癌代謝 / ピルビン酸キナーゼ / 膵癌 / 糖代謝活性 / 癌幹細胞 / 2-NBDG / 蛍光標識グルコース Except Principal Investigator 胆管癌 … More / BEX2 / がん幹細胞 / anticancer drug / adenovirus / clock gene / ルシフェラーゼアッセイ / サーカディアンリズム / per2 / 抗癌剤 / アデノウイルス / 時計遺伝子 / 遺伝子 / Fbw7 / ユビキチンリガーゼ / 胆道癌 Less

Dormant cancer stme cell-targeting therapy for cholangiocarcinoma
- Principal Investigator
  
  Kayayose Yu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Identification of a small compound targeting cancer stem cells in cholangiocarcinomaPrincipal Investigator
- Principal Investigator
  
  Yamamoto Kuniharu
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Miyagi Prefectural Hospital Organization Miyagi Cancer Center
Identification of PKM as a target for pancreatic cancer therapyPrincipal Investigator
- Principal Investigator
  
  Yamamoto Kuniharu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Miyagi Prefectural Hospital Organization Miyagi Cancer Center
Analysis of carcinogenic mechanism of biliary tract cancer from the protein control by ubiquitin ligase Fbw7
- Principal Investigator
  
  KATAYOSE Yu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
糖代謝活性を応用した癌幹細胞の新規同定法の開発Principal Investigator
- Principal Investigator
  
  山本久仁治
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Tohoku University
Development of a cancer gene therapy based on circadian rhythm
- Principal Investigator
  
  KAYAYOSE Yu
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University

All 2020 2018 2012 2011

All Journal Article

[Journal Article] BEX2 suppresses mitochondrial activity and is required for dormant cancer stem cell maintenance in intrahepatic cholangiocarcinoma2020
- Author(s)
  Tamai Keiichi、Nakamura-Shima Mao、Shibuya-Takahashi Rie、Kanno Shin-Ichiro、Yasui Akira、Mochizuki Mai、Iwai Wataru、Wakui Yuta、Abue Makoto、Yamamoto Kuniharu、Miura Koh、Mizuma Masamichi、Unno Michiaki、Kawamura Sadafumi、Sato Ikuro、Yasuda Jun、Yamaguchi Kazunori、Sugamura Kazuo、Satoh Kennichi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 21592-21592
- DOI
  10.1038/s41598-020-78539-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16432, KAKENHI-PROJECT-20K17068, KAKENHI-PROJECT-19H03795, KAKENHI-PROJECT-17K07193, KAKENHI-PROJECT-17K09469, KAKENHI-PROJECT-17K10716, KAKENHI-PROJECT-17K11166, KAKENHI-PROJECT-19K08430, KAKENHI-PROJECT-18K15799
[Journal Article] CD109 promotes the tumorigenic ability and metastatic motility of pancreatic ductal adenocarcinoma cells2020
- Author(s)
  Hatsuzawa Yuuri、Yamaguchi Kazunori、Takanashi Tomoka、Sato Ikuro、Tamai Keiichi、Mochizuki Mai、Iwai Wataru、Wakui Yuta、Abue Makoto、Yamamoto Kuniharu、Yasuda Jun、Mizuma Masamichi、Unno Michiaki、Sugamura Kazuo
- Journal Title
  
  Pancreatology
  
  Volume: 20 Issue: 3 Pages: 493-500
- DOI
  10.1016/j.pan.2020.01.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05410, KAKENHI-PROJECT-19K17416, KAKENHI-PROJECT-20K17068, KAKENHI-PROJECT-17K07193, KAKENHI-PROJECT-17K09469, KAKENHI-PROJECT-17K10716, KAKENHI-PROJECT-19K08430, KAKENHI-PROJECT-18K15799
[Journal Article] Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species2018
- Author(s)
  Yokoyama Misa、Tanuma Nobuhiro、Shibuya Rie、Shiroki Takeharu、Abue Makoto、Yamamoto Kuniharu、Miura Koh、Yamaguchi Kazunori、Sato Ikuro、Tamai Keiichi、Satoh Kennichi
- Journal Title
  
  International Journal of Oncology
  
  Volume: 52 Pages: 881-891
- DOI
  10.3892/ijo.2018.4258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19356, KAKENHI-PROJECT-17K10660, KAKENHI-PROJECT-15K09055, KAKENHI-PROJECT-17K10716
[Journal Article] Lymph nodes metastasis is a risk factor for bone metastasis from extrahepatic cholangiocarcinoma2012
- Author(s)
  Katayose Y, Nakagawa K, Yamamoto K, Yoshida H, Hayashi H, Mizuma M, Ohtsuka H, Fukase K, Onogawa T, Motoi F, Rikiyama T, Egawa S, Unno M
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 59(118) Pages: 1758-1760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390252
[Journal Article] An analysis of asecond-line S-1 monotherapy for gemcitabine-refractory biliary tract cancer2012
- Author(s)
  Katayose Y, Ohtsuka H, Kitamura Y, Masuda K, Nakagawa K, Yamamoto K, Yoshida H, Onogawa T, Motoi F, Naitoh T, Rikiyama T, Egawa S, Unno M.
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 59(115) Pages: 691-695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390252
[Journal Article] Phase I trial of neoadjuvant chemoradiation with gemcitabine and surgical resection for cholangiocarcinoma patients (NACRAC study)2011
- Author(s)
  Katayose Y, Rikiyama T, Motoi F, Yamamoto K, Yoshida H, Morikawa T, Hayashi H, Kanno A, Hirota M, Satoh K, Ariga H, Suzuki M, Ohyauchi M, Kondo Y, Ikeya S, Ogawa Y, Shimosegawa T, Egawa S, Unno M.
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 58(112) Pages: 1866-1872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390252

1. KATAYOSE Yu (20302151)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. 玉井恵一 (40509262)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YOSHIDA Hiroshi (60436152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. NAKAGAWA Kei (20542294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. HAYASHI Hiroshi (30422124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. UNNO Michiaki (70282043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. RIKIYAMA Toshiki (80343060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中山啓子 (60294972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佐藤賢一 (10282055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 田沼延公 (40333645)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 及川昌也 (30372296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 高見一弘 (30823728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 高橋莉恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 虻江誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamamoto Kuniharu 山本 久仁治

山本 久仁治 ヤマモト クニハル

YAMAMOTO Kuniharu 山本 久仁治

Research Projects

Research Products

Co-Researchers

Dormant cancer stme cell-targeting therapy for cholangiocarcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of a small compound targeting cancer stem cells in cholangiocarcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of PKM as a target for pancreatic cancer therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of carcinogenic mechanism of biliary tract cancer from the protein control by ubiquitin ligase Fbw7

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

糖代謝活性を応用した癌幹細胞の新規同定法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a cancer gene therapy based on circadian rhythm

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] BEX2 suppresses mitochondrial activity and is required for dormant cancer stem cell maintenance in intrahepatic cholangiocarcinoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD109 promotes the tumorigenic ability and metastatic motility of pancreatic ductal adenocarcinoma cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lymph nodes metastasis is a risk factor for bone metastasis from extrahepatic cholangiocarcinoma2012

Author(s)

Journal Title

Data Source

[Journal Article] An analysis of asecond-line S-1 monotherapy for gemcitabine-refractory biliary tract cancer2012

Author(s)

Journal Title

Data Source

[Journal Article] Phase I trial of neoadjuvant chemoradiation with gemcitabine and surgical resection for cholangiocarcinoma patients (NACRAC study)2011

Author(s)

Journal Title

Data Source

Yamamoto Kuniharu 山本久仁治

山本久仁治ヤマモトクニハル

YAMAMOTO Kuniharu 山本久仁治