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AKUTSU Yasunori  阿久津 泰典

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… Alternative Names

阿久津 泰典  アクツ ヤスノリ

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Researcher Number 00375677
Affiliation (based on the past Project Information) *help 2012 – 2016: 千葉大学, 医学(系)研究科(研究院), 講師
2011: 千葉大学, 大学院医学研究院, 講師
2010 – 2011: 千葉大学, 大学院・医学研究院, 講師
2008 – 2009: 千葉大学, 大学院・医学研究院, 助教
2006: 千葉大学, 医学部附属病院, 助手
2005: 千葉大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Digestive surgery / Tumor therapeutics / Tumor immunology
Except Principal Investigator
Digestive surgery
Keywords
Principal Investigator
食道癌 / ナノテクノロジー / 温熱療法 / ヒートショックプロテイン / 免疫療法 / 扁平上皮癌 / 樹状細胞 / 細胞 / 細胞療法 / ヒートショックプロティン / gp96 / 放射線療法 … More
Except Principal Investigator
… More 分子治療 / エピジェネティクス / 食道癌 / 発現制御 / 遺伝子変異 / がん抑制遺伝子 / 全ゲノムシーケンス / 発癌制御 / トランスレーショナルリサーチ / 遺伝子 / 癌 / 外科 / エピゲノム / ゲノム / 国際情報交流 / 国際情報交換 / マイクロRNA / 食道外科学 / エピジネティクス / micro RNA / 細胞内分子移動 / 消化器癌 / 分子標的治療 / ヒストンアセチル化 Less
  • Research Projects

    (8 results)
  • Research Products

    (40 results)
  • Co-Researchers

    (9 People)
  •  PD-1阻害免疫賦活ナノ粒子と電磁加温を用いた食道癌に対する樹状細胞療法の開発Principal Investigator

    • Principal Investigator
      阿久津 泰典
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Chiba University
  •  The attempt of new molecular therapy for esophageal cancer using the analysis of regulation concerning genome and epigenome

    • Principal Investigator
      Matsubara Hisahiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba University
  •  A combination therapy with hyperthermia and immunotherapy using dextran magnetic nanoparticle for esophageal cancerPrincipal Investigator

    • Principal Investigator
      AKUTSU Yasunori
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor immunology
    • Research Institution
      Chiba University
  •  Expression and functional analysis of miR-203 related to proliferation, invasion, and metastasis in esophageal cancer

    • Principal Investigator
      MORI Mikito
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba University
  •  A research for new cancer vaccine with heat shock protein for esophageal cancerPrincipal Investigator

    • Principal Investigator
      AKUTSU Yasunori
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba University
  •  Creation of molecular therapy for gastrointestinal cancer using inhibition of intra cellular molecular transport and regulation of epigenetics

    • Principal Investigator
      MATSUBARA Hisahiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba University
  •  NKT細胞および樹状細胞を介した食道癌に対する放射線併用免疫療法の開発Principal Investigator

    • Principal Investigator
      阿久津 泰典
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba University
  •  食道癌に対するヒストンのアセチル化制御による癌治療の試み

    • Principal Investigator
      MATSUBARA Hisahiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Chiba University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2006 2005 Other

All Journal Article Presentation Other

  • [Journal Article] Fra-1 Regulates the Expression of HMGA1, Which is Associated with a Poor Prognosis in Human Esophageal Squamous Cell Carcinoma.2016

    • Author(s)
      Toyozumi T, Hoshino I, Takahashi M, Usui A, Akutsu Y, Hanari N, Murakami K, Kano M, Akanuma N, Suitoh H, Matsumoto Y, Sekino N, Komatsu A, Matsubara H.
    • Journal Title

      Ann Surg Oncol.

      Volume: Nov 23.[Epubahead of print]

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293298
  • [Journal Article] Heterogeneity of Glucose Metabolism in Esophageal Cancer Measured by Fractal Analysis of Fluorodeoxyglucose Positron Emission Tomography Image: Correlation between Metabolic Heterogeneity and Survival.2016

    • Author(s)
      Tochigi T, Shuto K, Kono T, Ohira G, Tohma T, Gunji H, Hayano K, Narushima K, Fujishiro T, Hanaoka T, Akutsu Y, Okazumi S, Matsubara H.
    • Journal Title

      Dig Surg.

      Volume: Dec 9. [Epub ahead of print]

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293298
  • [Journal Article] Treatment of near-infrared photodynamic therapy using a liposomally formulated indocyanine green derivative for squamous cell carcinoma2015

    • Author(s)
      Maruyama T, Akutsu Y, Suganami A, Tamura Y, Fujito H, Ouchi T, Akanuma N, Isozaki Y, Takeshita N, Hoshino I, Uesato M, Toyota T, Hayashi H, Matsubara H
    • Journal Title

      PLoS One

      Volume: 10 Issue: 4 Pages: e0122849-e0122849

    • DOI

      10.1371/journal.pone.0122849

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24501328, KAKENHI-PROJECT-24591933, KAKENHI-PROJECT-25460328, KAKENHI-PROJECT-26670596
  • [Journal Article] A COX-2 inhibitor enhances the antitumor effects of chemotherapy and radiotherapy for esophageal squamous cell carcinoma.2014

    • Author(s)
      Yusup G, Akutsu Y. et al
    • Journal Title

      Int J Oncol

      Volume: 44 Issue: 4 Pages: 1146-52

    • DOI

      10.3892/ijo.2014.2300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501328
  • [Journal Article] Correlation between gp96 expression and the surgical outcome in patients with esophageal squamous cell carcinoma.2011

    • Author(s)
      Akutsu Y, Matsubara H, Kano M, etal.
    • Journal Title

      Ann Surg Onco1

      Volume: 18 Pages: 832-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390351
  • [Journal Article] Correlation between gp96 expression and the surgical outcome in patients with esophageal squamous cell carcinoma2011

    • Author(s)
      Y. Akutsu, et al
    • Journal Title

      Annals of Surgical Oncology

      Volume: 18 Pages: 832-837

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791268
  • [Journal Article] COX2 Expression Predicts Resistance to Chemoradiotherapy in Esophageal Squamous Cell Carcinoma2011

    • Author(s)
      Y.Akutsu, et al.
    • Journal Title

      Annals of Surgical Oncology

      Volume: 18 Pages: 131-138

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791268
  • [Journal Article] COX2 expression predicts resistance to chemoradiotherapy in esophageal squamous cell carcinoma2011

    • Author(s)
      Y. Akutsu, et al
    • Journal Title

      Annals of Surgical Oncology

      Volume: 18 Pages: 2946-51

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791268
  • [Journal Article] COX2 Expression Predicts Resistance to Chemoradiotherapy in Esophageal Squamous Cell Carcinoma.2011

    • Author(s)
      Akutsu Y, Hanari N, Yusup G, ほか, Matsubara H.
    • Journal Title

      Ann Surg Oncol

      Volume: (Epub)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390351
  • [Journal Article] COX2 Expression Predicts Resistance To Chemoradiotherapy in Esophageal Squamous Cell Carcinoma.2011

    • Author(s)
      Akutsu Y, Hanari N, Yusup G, Komatsu-Akimoto A,Ikeda N, Mori M, Yoneyama Y, Endo S, Miyazawa Y, Matsubara H
    • Journal Title

      Ann Surg Oncol.

    • Data Source
      KAKENHI-PROJECT-20390351
  • [Journal Article] Correlation between gp96 expression and the surgical outcome in patients with esophageal squamous cell carcinoma.2011

    • Author(s)
      Akutsu Y, Matsubara H, Kano M, Usui A, Yoneyama Y, Ikeda N, Komatsu A, Yusup G
    • Journal Title

      Ann Surg Oncol. 18(3)

      Pages: 832-7

    • Data Source
      KAKENHI-PROJECT-20390351
  • [Journal Article] miR-145, miR-133a and miR-133b : Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma.2010

    • Author(s)
      Kano M, Seki N, Kikkawa N, Fujimura L, Hoshino I, Akutsu Y, Chiyomaru T, Enokida H, Nakagawa M, Matsubara H
    • Journal Title

      Int J Cancer. 127(12)

      Pages: 804-14

    • Data Source
      KAKENHI-PROJECT-20390351
  • [Journal Article] CHAP31 induces apoptosis only via the intrinsic pathway in human esophageal cancer cells.2010

    • Author(s)
      Murakami K, Matsubara H, Hoshino I, Akutsu Y, Miyazawa Y, Matsushita K, Sakata H, Nishimori T, Usui A, Kano M, Nishino N, Yoshida M
    • Journal Title

      Oncology. 78(1)

      Pages: 62-74

    • Data Source
      KAKENHI-PROJECT-20390351
  • [Journal Article] Effects of carbon-ion radiotherapy combined with a novel histone deacetylase inhibitor, cyclic hydroxamic-acid-containing peptide 31 in human esophageal squamous cell carcinoma.2009

    • Author(s)
      Kano M, Yamada S, Hoshino I, Murakami K, Akutsu Y, Sakata H, Nishimori T, Usui A, Miyazawa Y, Kamada T, Tsujii H, Matsubara H
    • Journal Title

      Anticancer Res. 29(11)

      Pages: 4433-8

    • Data Source
      KAKENHI-PROJECT-20390351
  • [Journal Article] Combined effects of p53 gene therapy and leptomycin B in human esophageal squamous cell carcinoma.2008

    • Author(s)
      Hoshino I, Matsubara H, Komatsu A, Akutsu Y, Nishimori T, Yoneyama Y, Murakami K, Sakata H, Matsushita K, Miyazawa Y, Brooks R, Yoshida M, Ochiai T
    • Journal Title

      Oncology. 75(1-2)

      Pages: 113-9

    • Data Source
      KAKENHI-PROJECT-20390351
  • [Journal Article] Combined effects of p53 gene therapy and leptomycin B in human esophageal sauamous cell carcinoma.2008

    • Author(s)
      Hoshino I, Matsubara H, Komatsu A, Akutsu Y, et al.
    • Journal Title

      Oncology 75

      Pages: 113-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390351
  • [Journal Article] Role of histone deacetylase inhibitor in adenovirus-mediated p53 genetherapy in esophageal cancer.2008

    • Author(s)
      Hoshino I, Matsubara H, Akutsu Y, et al.
    • Journal Title

      Anticancer Res. 28

      Pages: 665-671

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390351
  • [Journal Article] The combination of radiation and direct intratumoral injection of dendritic cells enhances systemic antitumor effect.2006

    • Author(s)
      Y.Akutsu
    • Journal Title

      The journal of cancer surgery 32(Suppl I)

    • Data Source
      KAKENHI-PROJECT-17790906
  • [Journal Article] 放射線併用樹状細胞局注療法の有用性についての検討-放射線照射はGp96no発現を増強させ腫瘍の抗原性を高める-2005

    • Author(s)
      阿久津泰典
    • Journal Title

      Biotherapy 19(Suppl I)

      Pages: 103-103

    • Data Source
      KAKENHI-PROJECT-17790906
  • [Presentation] Usefulness of exosome quantification by cholesteryl ester transfer protein activity as a biomarker for human esophageal squamous cell carcinoma (ESCC)2016

    • Author(s)
      Yasunori Matsumoto, Masayuki Kano, Yasunori Akutsu, Naoyuki Hanari, Isamu Hoshino, Kentaro Murakami, Akihiro Usui, Hiroshi Suito, Masahiko Takahashi, Ryota Otsuka, Hisahiro Matsubara
    • Organizer
      AACR Annual Meeting 2016
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Year and Date
      2016-04-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293298
  • [Presentation] The expression analysis of ZNF750 as biomarker in human esophageal squamous cell carcinoma2016

    • Author(s)
      Ryota Otsuka, Yasunori Akutsu, Naoyuki Hanari, Kentaro Murakami, Masayuki Kano, Masahiko Takahashi, Yasunori Matsumoto, Nobufumi Sekino, Masaya Yokoyama, Hisahiro Matsubara
    • Organizer
      40th World Congress of the International College of Surgeons
    • Place of Presentation
      京都国際会館 (京都府 京都市)
    • Year and Date
      2016-10-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293298
  • [Presentation] A paradoxical observation for its upregulation and the prognostic significance about miR-7 in esophageal squamous cell carcinoma2016

    • Author(s)
      Masayuki Kano , Yasunori Matsumoto , Masahiko Takahashi , Naoki Akanuma, Kentaro Murakami , Yasunori Akutsu, Hisahiro Matsubara
    • Organizer
      AACR Annual Meeting 2016
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Year and Date
      2016-04-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293298
  • [Presentation] Analysis of allele specific expression in esophageal squamous cell carcinoma using exome sequencing and mRNA sequencing2015

    • Author(s)
      高橋理彦,細道一善,星野敢,阿久津泰典,村上健太郎,井ノ上逸朗,松原久裕
    • Organizer
      The 74th Annual Meeting of the Japanese Canser Association
    • Place of Presentation
      名古屋国際会議場・愛知県・名古屋市
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26293298
  • [Presentation] 食道癌における血中PD-1関連タンパクのバイオマーカーとしての可能性2015

    • Author(s)
      阿久津泰典
    • Organizer
      第36回癌免疫外科研究会
    • Place of Presentation
      奄美観光ホテル・鹿児島県・奄美市
    • Year and Date
      2015-05-14
    • Data Source
      KAKENHI-PROJECT-15K06867
  • [Presentation] 新規温熱治療の基礎と臨床(招待講演)2013

    • Author(s)
      阿久津泰典
    • Organizer
      日本ハイパーサーミア学会第30回大会
    • Place of Presentation
      横浜市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24501328
  • [Presentation] A novel Dendritic Cell Therapy with Oncothermia Therapy mediated by abscopal effect2012

    • Author(s)
      Wei Qin, Yasunori Akutsu, Yutaka Tamura, Gabor Andocs, Gulbostan Yusup, Xin Hu, Hisahiro Matsubara
    • Organizer
      Conference of the International Clinical Hyperthermia Society,2012
    • Place of Presentation
      ハンガリー・ブタペスト市
    • Data Source
      KAKENHI-PROJECT-24501328
  • [Presentation] ナノ粒子ICG-Liposomeと光線力学的による扁平上皮癌に対する温熱療法の開発2012

    • Author(s)
      丸山 哲郎, 阿久津 泰典, 星野 敢, 森 幹人, 羽成 直行, 藤戸 廣迪, 菅波 晃子, 田村 裕, 林 秀樹, 松原 久裕
    • Organizer
      第66回日本食道学会総会
    • Place of Presentation
      軽井沢市
    • Data Source
      KAKENHI-PROJECT-24501328
  • [Presentation] 食道扁平上皮癌におけるmiR-203の発現機能解析2012

    • Author(s)
      竹下修由森幹人阿久津泰典松原久裕ら
    • Organizer
      第67回日本消化器外科学会総会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-23591918
  • [Presentation] 食道扁平上皮癌におけるmiR-203の発現機能解析2012

    • Author(s)
      竹下修由森幹人阿久津泰典松原久裕ら
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23591918
  • [Presentation] 食道扁平上皮癌におけるリンパ節転移と免疫マーカーとしてのgp96発現の検討2011

    • Author(s)
      阿久津泰典
    • Organizer
      第65回日本食道学会学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2011-09-26
    • Data Source
      KAKENHI-PROJECT-21791268
  • [Presentation] 食道癌における免疫学的バイオマーカーとしてのgp96発現の意義2011

    • Author(s)
      阿久津泰典
    • Organizer
      第21回癌免疫外科研究会
    • Place of Presentation
      和歌山
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-21791268
  • [Presentation] Correlation between gp96 expression and the surgical outcome in patients with esophageal squamous cell carcinoma2011

    • Author(s)
      Akutsu Y., et al
    • Organizer
      International Surgical Week 2011 (ISDS)
    • Place of Presentation
      Yokohama
    • Year and Date
      2011-08-28
    • Data Source
      KAKENHI-PROJECT-21791268
  • [Presentation] Antitumor effect for squamous cell carcinoma mediated by heat shock protein gp962010

    • Author(s)
      Akutsu Y, et al
    • Organizer
      2010年AACR-JCA合同会議
    • Place of Presentation
      Waikoloa, Hawai(U.S.A.)
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21791268
  • [Presentation] Fra-1 is an independent prognostic factor in esophageal squamous cell carcinoma and related to cell proliferation, migration and invasion in vitro.2010

    • Author(s)
      Matsubara H, Usui, A, Akutsu, Y, etal.
    • Organizer
      22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-20390351
  • [Presentation] Antitumor effect for squamous cell carcinoma mediated by heat shock protein gp962010

    • Author(s)
      Y. Akutsu, et al
    • Organizer
      2010年AACR-JCA合同会議
    • Place of Presentation
      aikoloa, Hawai (U.S.A.)
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21791268
  • [Presentation] Fra-1 is an independent prognostic factor in esophageal squamous cell carcinoma and related to cell proliferation, migration and invasion in vitro.2010

    • Author(s)
      Matsubara H, Usui A, Akutsu Y, et al
    • Organizer
      22nd EORTC-NCI-AACR Symposium on MolecularTargets and Cancer Therapeutics
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-20390351
  • [Presentation] CHAP31 Induces Apoptosis Only via the Intrinsic Pathway in Human Esophageal Cancer Cells.2009

    • Author(s)
      Matsubara H, Murakami K, Akutsu Y, Nishino N, Yoshida M
    • Organizer
      8th AACR-JCA Joint Conference
    • Place of Presentation
      Kona, Hawaii, USA
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-20390351
  • [Presentation] CHAP31 Induces Apoptosis Only via the Intrinsic Pathway in Human Esophageal Cancer Cells2009

    • Author(s)
      Hisahiro Matsubaral, Kentaro Murakami, Yasunori Akutsul, Norikazu Nishino, Minoru Yoshida
    • Organizer
      8^<th> AACR-JCA Joint Conference
    • Place of Presentation
      Kona, Hawaii, USA
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-20390351
  • []

  • []

  • 1.  MATSUBARA Hisahiro (20282486)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 22 results
  • 2.  TAMURA Yutaka (50263174)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 3.  MORI Mikito (90399452)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  KAWAHIRA Hiroshi (90447285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SUZUKI Kazufumi (00586737)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  落合 武徳 (80114255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  浦島 哲郎 (80375625)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  井ノ上 逸朗 (00192500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  村上 健太郎 (40436382)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results

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