isaka yoshitaka 猪阪善隆

… Alternative Names

Researcher Number	00379166
Other IDs
Affiliation (Current)	2022: 大阪大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2021: 大阪大学, 医学系研究科, 教授 2015 – 2016: 大阪大学, 医学(系)研究科(研究院), 教授 2015: 大阪大学, 大学院医学系研究科, 教授 2014: 大阪大学, 大学院医学系研究科, 准教授 2010 – 2014: 大阪大学, 医学(系)研究科(研究院), 准教授 … More
Review Section/Research Field	Principal Investigator Kidney internal medicine / General internal medicine(including psychosomatic medicine) / Basic Section 53040:Nephrology-related / Medium-sized Section 53:Organ-based internal medicine and related fields Except Principal Investigator Kidney internal medicine / Urology / Basic Section 53040:Nephrology-related / Basic Section 58060:Clinical nursing-related / Clinical nursing / Epidemiology and preventive medicine / Physical pharmacy / Basic Section 58010:Medical management and medical sociology-related / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
Keywords	Principal Investigator 腎炎 / オートファジー / リソソーム / 腎臓内科 / 尿細管 / siRNA / TGF-beta / eri-1 / Single cell RNA seq / 幹細胞 … More Except Principal Investigator オートファジー / 腎移植 / リソソーム / 近位尿細管 / ミトコンドリア / 免疫寛容 / 腎臓リハビリテーション / 行動分析学 / 虚血・再灌流 / 腎臓 / アポトーシス / 腎臓移植 / 制御性T細胞 / MF-1遺伝子導入 / CD34+幹細胞 / ドナー特異的な免疫寛容 / Tregバンク / CD28SA / p62 / 慢性腎臓病 / MRI / 運動療法 / 医療・福祉 / GFP / PDGF / オートファジーフラックス / リポファジー / 尿細管 / 分析化学 / 光学分割 / アミノ酸 / 虚血再灌流 / 経口免疫寛容 / 虚血再灌流障害 / 尿細管細胞 / LC-3 / 細胞死 / superagonistCD28抗体 / Foxp3 / Bcl-2 / CTLA4-Ig / ICOS-Ig / CD28-Ig / MF-1 / CTLA4-I / CD28-Superagonist / 非特異的免疫制御細胞 / Treg バンク / レンチウイルス / 超音波照射遺伝子導入法 / 幹細胞共培養 / CD28 / スーパーアゴニスト / FoxP3 / 抗GBM抗体腎炎 / 半月体形成性糸球体腎炎 / CD163 / 半月体形成性腎炎 / Thy-1腎炎 / シスプラチン / タンパク凝集体 / 虚血再還流 / クロロキン / シクロスポリン / 代謝ストレス / シスプラチン腎症 / 虚血再還流傷害 / LC3 / 細胞内封入体 / 老化 / アシドーシス / ミトファジー / 酸化ストレス / アンモニア / 臓器障害 / 移植グラフト / 組織障害 / BOLD MRI / 拡散MRI / 拡散テンソルMRI / q space imaging / 移植腎繊維化 / epigenetics / epigenome / histone modification / gene expression / histone acetylation / epigeneticcs / Chip-seq / 転写促進因子 / 転写抑制因子 / cell hypertrophy / 25(OH)D / 腎尿細管間質線維化 / ビタミンD / 1,25(OH)2D / マクロファージ / ビタミンＤ / ２５ヒドロキシビタミンＤ / 25ヒドロキシビタミンＤ / 透析看護 / 価値割引 / サルコペニア / フレイル / 運動能力 / 運動評価 / 価値判断 / CD28-Supergonist / 非特異的免疫抑制細胞 / Ｔｒｅｇバンク / ﾄﾞﾅｰ特異的な免疫寛容 / 再生医療 / SP細胞 / 胎児マイクロキメリズム / 幹細胞 / マイクロキメリズム / 肝臓 / 妊娠 / ネフロン / 概日リズム / 骨髄 / レチノイン酸 / ネフリン / kidney / regenerative medicine / SP cell / fetal microchimerism / 脂肪毒性 / イコサペント酸エチル / 高脂肪食負荷 / 飢餓 / 糖尿病性腎症 / 腎繊維化 / DTI / DTI MRI / 腎臓繊維化 / 健康管理アプリ / 塩分制限 / 減塩 / 降圧 / ゲーム / 塩分制限食と血圧 / プロトタイプ作成 / メタボロミクス / 膜性腎症 / ネフローゼ症候群 / 臨床 / 遺伝子 / Rubicon / メボリック症候群 / 肥満 / 生理学 / 脂質 / 糖尿病 / ADTKD / MUC1 / VNTR / 小胞体ストレス / 細胞内凝集 / transgenic mouse / ER stress / 家族性尿細管間質腎炎 / 次世代シークエンサー / 全エクソーム解析 / 腎臓内科 / 家族性疾患 / 尿細管間質腎炎 / 腎臓学 / シュウ酸腎症 / TFEB / 結晶腎症 / リソソームストレス / LMP / 脂質代謝 / 透析 / PPARα / 急性腎障害 / 脂肪滴 / PGC1α / 過酸化脂質 / 生体ドナー / 移植時生検 / 腎予後 / SNS / 地域包括ケア / PDカフェ / peer-to-peer / ネットワーク / 腹膜透析 / 多次元HPLC / 定量メタボロミクス / 血液透析 / 遠隔支援システム / 在宅 / Mondo / 遺伝性疾患 / 高血圧 / 低マグネシウム血症 / 低カリウム血症 / ankyrin Less

早期CKD患者の精密医療を目指した予後評価法の開発Principal Investigator
- Principal Investigator
  
  猪阪善隆
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Osaka University
IoT機器を活用した在宅腎臓リハビリテーションの遠隔支援システムの構築
- Principal Investigator
  
  飛田伊都子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Jikei University of Health Care Sciences
転写因子Mondoによる腎近位尿細管オートファジー・エネルギー代謝制御機構の解明
- Principal Investigator
  
  高畠義嗣
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Osaka University
molecular genetic analyses of a family with hereditary hypo Mg, hypo K ,and hypertension
- Principal Investigator
  
  貝森淳哉
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Osaka University
急性腎障害におけるリポファジーの役割解明と治療への応用
- Principal Investigator
  
  高橋篤史
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Osaka University
移植時生検を用いたドナーの腎予後予測～超解像度顕微鏡を用いた病理学的因子の探索
- Principal Investigator
  
  難波倫子
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Osaka University
The importance of peer-to-peer networking in the community-based integrated care systems
- Principal Investigator
  
  北村温美
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Osaka University
定量キラルメタボロミクスを実現する三次元LC分析基盤開発と腎・心不全の早期診断
- Principal Investigator
  
  濱瀬健司
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kyushu University
Elucidation of renal disease onset and progression mechanism using single cell RNA-sequencePrincipal Investigator
- Principal Investigator
  
  ISAKA YOSHITAKA
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Osaka University
Lysosomal stress as an emerging target in kidney disease
- Principal Investigator
  
  Takabatake Yoshitsugu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Osaka University
Effects of physical exercise continuation support system in renal rehabilitation
- Principal Investigator
  
  Tobita Itoko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Graduate School of Health Care Science, Jikei Institute
Development of a new therapy for lifestyle-related CKD targeting autophagy recycling systemPrincipal Investigator
- Principal Investigator
  
  ISAKA YOSHITAKA
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
Early and minimally invasive diagnosis of kidney failure using chiral amino acid metabolomics
- Principal Investigator
  
  Kenji Hamase
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyushu University
Research on diagnosis, treatment and epidemiology of membrane nephropathy in the Asia-Pacific region
- Principal Investigator
  
  maruyama Shoichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Nagoya University
Autophagic inhibitor Rubicon in proximal tubules can be a therapeutic target for metabolic syndrome-related kidney disease.
- Principal Investigator
  
  Takahashi Atsushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
a molecular biology study of Autosomal dominant tubulointerstitial kidney disease by using mutated MUC1 cDNA sequence identified in our own patient family.
- Principal Investigator
  
  Kaimori Junya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
Unraveling the Role of Autophagy in Counteracting Lipotoxicity in the Kidney
- Principal Investigator
  
  Takabatake Yoshitsugu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
Development of non-invasive bioimaging techniques for evaluation of transplantation related kidney injury.
- Principal Investigator
  
  Shiro Takahara
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Osaka University
A development of serious game for therapeutic patient education about salt restriction
- Principal Investigator
  
  Kitamura Harumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Osaka University
Development of a new therapy by regulating histone acetylationPrincipal Investigator
- Principal Investigator
  
  ISAKA Yoshitaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Osaka University
Direct effects of 25-hydroxyvitamin D on renal fibrosis
- Principal Investigator
  
  Matsui Isao
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
Investigation of effects of daily living and long-term continuing factors on renal rehabilitation
- Principal Investigator
  
  Tobita Itoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical nursing
- Research Institution
  Graduate School of Health Care Sciences, Jikei Institute
The permanent survival of allografts by tolerance induction mediated by the combined therapy of adoptive transfer of Treg cells and the MF-1-gene transfection
- Principal Investigator
  
  Azuma Haruhito
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Osaka Medical College
Basic research of new epigenetic marker, H4K20ac
- Principal Investigator
  
  Kaimori Jun-Ya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
Role of autophagy in kidney aging and metabolic acidosis
- Principal Investigator
  
  TAKABATAKE Yoshitsugu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
Investigating a new therapeutic approach from autophagy-deficient associated proteinPrincipal Investigator
- Principal Investigator
  
  ISAKA Yoshitaka
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
establishment of a new evaluation technique by none envasive MRI
- Principal Investigator
  
  TAKAHARA Shiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Osaka University
The role of autophagy in renal ischemia-reperfusion injury
- Principal Investigator
  
  KITAMURA Harumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
Novel approach of induction of donor specific immune tolerance: adoptive transfer of Treg cells combined with MF1 gene transfection
- Principal Investigator
  
  AZUMA Haruhito
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Osaka Medical College
Transplantation of allogenic fetal membrane-derived mesenchymal stem cells protect kidneyPrincipal Investigator
- Principal Investigator
  
  ISAKA Yoshitaka
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
Therapeutic effect of CD28 superagonist on renal disease via expansion of regulatory T cells
- Principal Investigator
  
  TAKABATAKE Yoshitsugu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
慢性移植腎症におけるオートファジーの関与の解明
- Principal Investigator
  
  高原史郎
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Osaka University
3種抗体、および、レンチウイルスを用いた移植腎生着延長の試み
- Principal Investigator
  
  東治人
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Osaka Medical College
Induction of kidney graft tplerance using donor-specofoc regulatory T cells
- Principal Investigator
  
  TAKAHARA Shiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Osaka University
虚血・低酸素による尿細管傷害ならびに腎発生におけるオートファジーの関与
- Principal Investigator
  
  IMAI Enyu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
ラット腎移植モデルにおける経口免疫寛容の導入
- Principal Investigator
  
  市丸直嗣
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Osaka University
Gene therapy for progressive kidney diseases using siRNAPrincipal Investigator
- Principal Investigator
  
  ISAKA Yoshitaka
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University
Identification and characterization of stem cells for kidney
- Principal Investigator
  
  IMAI Enyu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka University

[Book] 腎と透析2016
- Author(s)
  松井　功、猪阪　善隆
- Total Pages
  4
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-26461227
[Book] Annual Review 腎臓20132013
- Author(s)
  猪阪善隆ら
- Total Pages
  350
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22590890
[Book] オートファジー不全による尿細管障害2013
- Author(s)
  猪阪善隆、木村友則、高畠義嗣
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22590890
[Journal Article] Single cell RNA sequencing uncovers cellular developmental sequences and novel potential intercellular communications in embryonic kidney2021
- Author(s)
  Isao Matsui, Ayumi Matsumoto, Kazunori Inoue, Yusuke Katsuma, Seiichi Yasuda, Karin Shimada, Yusuke Sakaguchi, Masayuki Mizui, Jun-Ya Kaimori, Yoshitsugu Takabatake, Yoshitaka Isaka
- Journal Title
  
  Sci Rep
  
  Volume: 11 Pages: 73-73
- DOI
  10.1038/s41598-020-80154-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08725, KAKENHI-PROJECT-19K22621
[Journal Article] Antioxidant role of autophagy in maintaining the integrity of glomerular capillaries2018
- Author(s)
  Matsuda J, Namba T, Takabatake Y, Kimura T, Takahashi A, Yamamoto T, Minami S, Sakai S, Fujimura R, Kaimori JY, Matsui I, Hamano T, Fukushima Y, Matsui K, Soga T, Isaka Y.
- Journal Title
  
  Autophagy
  
  Volume: 14 Pages: 53-65
- DOI
  10.1080/15548627.2017.1391428
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17859, KAKENHI-PROJECT-17H04188
[Journal Article] Analysis of an ADTKD family with a novel frameshift mutation in MUC1 reveals characteristic features of mutant MUC1 protein2017
- Author(s)
  Satoko Yamamoto, Jun-Ya Kaimori, Takuji Yoshimura, Tomoko Namba, Atsuko Imai, Kaori Kobayashi, Ryoichi Imamura, Naotsugu Ichimaru, Kazuto Kato, Akihiro Nakaya, Shiro Takahara, Yoshitaka Isaka
- Journal Title
  
  Ｎｅｐｈｒｏｌｏｇｙ　Ｄｉａｌｙｓｉｓ　Ｔｒａｎｓｐｌａｎｔａｔｉｏｎ
  
  Volume: ｉｎ　ｐｒｅｓｓ
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09615
[Journal Article] Stagnation of autophagy: A novel mechanism of renal lipotoxicity.2017
- Author(s)
  Takabatake Y, Yamamoto T, Isaka Y.
- Journal Title
  
  Autophagy
  
  Volume: 13 Pages: 775-776
- DOI
  10.1080/15548627.2017.1283084
- Data Source
  KAKENHI-PROJECT-15K09260
[Journal Article] Diffusion Tensor Imaging MRI with spin echo sequence and long duration measurement was identified for evaluation of renal fibrosis in rat fibrosis model2017
- Author(s)
  Jun-Ya Kaimori, Yoshitaka Isaka, Masaki Hatanaka, Satoko Yamamoto, Naotsugu Ichimaru, Akihiko Fujikawa, Hiroshi Shibata, Akira Fujimori, Sosuke Miyoshi, Takashi Yokawa, Kagayaki Kuroda, Toshiki Moriyama, Hiromi Rakugi, Shiro Takahara
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 49 Pages: 145-152
- DOI
  10.1016/j.transproceed.2016.10.014
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10640
[Journal Article] Analysis of an ADTKD family with a novel frameshift mutation in MUC1 reveals characteristic features of mutant MUC1 protein.2017
- Author(s)
  Yamamoto S, Kaimori J, Yoshimura T, Namba T, Imai A, Kobayashi K, Imamura R, Ichimaru N, Kato K, Nakaya A, Takahara S, & Isaka Y
- Journal Title
  
  Nephrology, dialysis, transplantation
  
  Volume: 32 Pages: 2010-2007
- DOI
  10.1093/ndt/gfx083
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07222, KAKENHI-PROJECT-16K09615, KAKENHI-PROJECT-17K08632, KAKENHI-PROJECT-16K19404
[Journal Article] Lipophagy maintains energy homeostasis in the kidney proximal tubule during prolonged starvation2017
- Author(s)
  Minami Satoshi、Yamamoto Takeshi、Takabatake Yoshitsugu、Takahashi Atsushi、Namba Tomoko、Matsuda Jun、Kimura Tomonori、Kaimori Jun-ya、Matsui Isao、Hamano Takayuki、Takeda Hiroaki、Takahashi Masatomo、Izumi Yoshihiro、Bamba Takeshi、Matsusaka Taiji、Niimura Fumio、Isaka Yoshitaka
- Journal Title
  
  Autophagy
  
  Volume: 13 Pages: 1629-1647
- DOI
  10.1080/15548627.2017.1341464
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09260, KAKENHI-PROJECT-17H04188
[Journal Article] Autophagy Inhibits the Accumulation of Advanced Glycation End Products by Promoting Lysosomal Biogenesis and Function in the Kidney Proximal Tubules2017
- Author(s)
  Takahashi Atsushi、Takabatake Yoshitsugu、Kimura Tomonori、Maejima Ikuko、Namba Tomoko、Yamamoto Takeshi、Matsuda Jun、Minami Satoshi、Kaimori Jun-ya、Matsui Isao、Matsusaka Taiji、Niimura Fumio、Yoshimori Tamotsu、Isaka Yoshitaka
- Journal Title
  
  Diabetes
  
  Volume: 66 Pages: 1359-1372
- DOI
  10.2337/db16-0397
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04188
[Journal Article] High-Fat Diet-Induced Lysosomal Dysfunction and Impaired Autophagic Flux Contribute to Lipotoxicity in the Kidney.2017
- Author(s)
  Yamamoto T, Takabatake Y, Takahashi A, Kimura T, Namba T, Matsuda J, Minami S, Kaimori JY, Matsui I, Matsusaka T, Niimura F, Yanagita M, Isaka Y.
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: 印刷中
- DOI
  10.1681/asn.2016070731
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09260
[Journal Article] Visualization of kidney fibrosis in diabetic nephropathy by long diffusion tensor imaging MRI with spin-echo sequence2017
- Author(s)
  Kaimori JY, Isaka Y, Hatanaka M, Yamamoto S, Ichimaru N, Fujikawa A, Shibata H, Fujimori A, Miyoshi S, Yokawa T, Kuroda K, Moriyama T, Rakugi H, Takahara S
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Pages: 5731-5731
- DOI
  10.1038/s41598-017-06111-4
- Data Source
  KAKENHI-PROJECT-15K10640
[Journal Article] 医学と医療の最前線　腎疾患進行防御機構としてのオートファジー2017
- Author(s)
  猪阪善隆、山本毅士、難波倫子、高橋篤史、木村友則、高畠義嗣
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 106 Pages: 1206-1211
- NAID
  40021241462
- Data Source
  KAKENHI-PROJECT-15K09260
[Journal Article] 家族性尿細管間質腎炎2017
- Author(s)
  貝森淳哉、高原史郎、猪阪善隆
- Journal Title
  
  細胞
  
  Volume: 49 Pages: 475-478
- Data Source
  KAKENHI-PROJECT-16K09615
[Journal Article] Histone H4 lysine 20 acetylation is associated with gene repression in human cells2016
- Author(s)
  Kaimori, J. Y., Maehara, K., Hayashi-Takanaka, Y., Harada, A., Fukuda, M., Yamamoto, S., Ichimaru, N., Umehara, T., Yokoyama, S., Matsuda, R., Ikura, T., Nagao, K., Obuse, C., Nozaki, N., Takahara, S., Takao, T., Ohkawa, Y., Kimura, H., and Isaka, Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 24318-24318
- DOI
  10.1038/srep24318
- NAID
  120005770760
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06942, KAKENHI-PUBLICLY-15H01462, KAKENHI-PLANNED-25116005, KAKENHI-PROJECT-25503002, KAKENHI-PROJECT-25670410, KAKENHI-PROJECT-26291071, KAKENHI-PUBLICLY-16H01219, KAKENHI-PUBLICLY-16H01307, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-16H04739, KAKENHI-PROJECT-26281020, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-26293166, KAKENHI-PROJECT-15K12203, KAKENHI-PROJECT-26650002, KAKENHI-PROJECT-15K18457, KAKENHI-PROJECT-16K18479, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25116004
[Journal Article] Histone H4 lysine 20 acetylation is associated with gene repression in human cells.2016
- Author(s)
  Kaimori J, Maehara K, Hayashi-Takanaka Y, Harada A, Fukuda M, Yamamoto S, Ichimaru N, Umehara T, Yokoyama S, Matsuda R, Ikura T, Nagao K, Obuse C, Nozak Ni, akahara S, Takao T, Ohkawa Y, Kimura H, and Isaka Y
- Journal Title
  
  Scientific Reports
  
  Volume: in press
- NAID
  120005770760
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293166
[Journal Article] 腎臓のアンチエイジング機構としてのオートファジー2015
- Author(s)
  高畠義嗣、猪阪善隆、守山敏樹
- Journal Title
  
  腎臓内科・泌尿器科
  
  Volume: 未定
- NAID
  40022582461
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591196
[Journal Article] Excess 25-hydroxyvitamin D3 exacerbates tubulointerstitial injury in mice by modulating macrophage phenotype.2015
- Author(s)
  Kusunoki Y, Matsui I, Ｈａｍａｎｏ T, Shimomura A, Mori D, Yonemoto S, Takabatake Y, Tsubakihara Y, St-Arnaud R, Isaka Y, Rakugi H.
- Journal Title
  
  Ｋｉｄｎｅｙ　Ｉｎｔｅｒｎａｔｉｏｎａｌ
  
  Volume: ８８ Pages: 1013-29
- DOI
  10.1038/ki.2015.210
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461227
[Journal Article] 心停止後ラット腎臓のfunctional MRIを用いた詳細な障害の評価と腎移植後グラフト予後予測可能性2014
- Author(s)
  貝森淳哉、岩井聡美、小林英司、畑中雅喜、津田秀年、小尾佳嗣、奥見雅由、矢澤浩治、市丸直嗣、楽木宏美、野々村祝夫、猪阪善隆、高原史郎
- Journal Title
  
  Organ Biology
  
  Volume: 21（2） Pages: 179-181
- NAID
  130004715801
- Open Access
- Data Source
  KAKENHI-PROJECT-24659714
[Journal Article] Autophagic Clearance of Mitochondria in the Kidney Copes with Metabolic Acidosis.2014
- Author(s)
  Namba T, Takabatake Y, Kimura T, Takahashi A, Yamamoto T, Matsuda J, Kitamura H, Niimura F, Matsusaka T, Iwatani H, Matsui I, Kaimori J, Kioka H, Isaka Y, Rakugi H.
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: 25・10 Pages: 2254-2266
- DOI
  10.1681/asn.2013090986
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-22249033, KAKENHI-PROJECT-24659416
[Journal Article] Autophagy and the kidney: health and disease.2014
- Author(s)
  Takabatake Y, Kimura T, Takahashi A, Isaka Y.
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 未定
- DOI
  10.1093/ndt/gft535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591196
[Journal Article] Chloroquine in cancer therapy: a double-edged sword of autophagy.2013
- Author(s)
  Kimura T, Takabatake Y, Takahashi A, Isaka Y
- Journal Title
  
  Cancer Res.
  
  Volume: 73 Pages: 3-7
- Data Source
  KAKENHI-PROJECT-22590890
[Journal Article] Non-Invasive Magnetic Resonance Imaging in Rats for Prediction of the Fate of Grafted Kidneys from Cardiac Death Donors2013
- Author(s)
  J Kaimori, S Iwai, M Hatanaka, T Teratani, Y Obi,H Tsuda, Y Isaka, T Yokawa, K Kuroda, N Ichimaru,MOkumi, K Yazawa, H Rakugi, N Nonomura, S Takahara, E Kobayashi
- Journal Title
  
  PLOS ONE
  
  Volume: Volume 8 | Issue 5 |
- NAID
  130004715801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659714
[Journal Article] Chloroquine in cancer therapy; A double-edged sword of autophagy.2013
- Author(s)
  Kimura T, Takabatake Y, Takahashi A, Isaka Y
- Journal Title
  
  Cancer Research
  
  Volume: 73 Pages: 3-7
- DOI
  10.1158/0008-5472.can-12-2464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659416, KAKENHI-PROJECT-24890108
[Journal Article] Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury2013
- Author(s)
  Maejima I, Takahashi A, Omori H, Kimura T, Takabatake Y, Saitoh T, Yamamoto A, Hamasaki M, Noda T, Isaka Y, Yoshimori T
- Journal Title
  
  EMBO　J
  
  Volume: 32 Pages: 2336-2347
- DOI
  10.1038/emboj.2013.171
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23247034, KAKENHI-PROJECT-24659416, KAKENHI-PLANNED-25111002, KAKENHI-PUBLICLY-25117717, KAKENHI-PROJECT-25670027, KAKENHI-PROJECT-25840075
[Journal Article] Autophagy protects kidney proximal tubule epithelial cells from mitochondrial metabolic stress.2013
- Author(s)
  Kimura, T., Takahashi, A., Takabatake, Y., Namba, T, Yamamoto, T., Kaimori, J.Y., Matsui, I., Kitamura, H., Niimura, F., Matsusaka T., Soga, T., Rakugi, H., Isaka, Y.
- Journal Title
  
  Autophagy
  
  Volume: 9 Pages: 1876-1886
- DOI
  10.4161/auto.25418
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22134007, KAKENHI-PROJECT-24591196, KAKENHI-PROJECT-24659416
[Journal Article] 腎臓の老化とオートファジー2012
- Author(s)
  高畠義嗣　木村友則　猪阪善隆
- Journal Title
  
  日本腎臓学会誌
  
  Volume: 54 Pages: 78-85
- NAID
  10030563626
- Data Source
  KAKENHI-PROJECT-24591196
[Journal Article] Autophagy guards against cisplatin-induced acute kidney injury2012
- Author(s)
  Takahashi A, Kimura T, Takabatake Y, Namba T, Kaimori J, Kitamura H, Matsui I, Niimura F, Matsusaka T, Fujita N, Yoshimori T, Isaka Y, Rakugi H.
- Journal Title
  
  Am J Pathol
  
  Volume: 180 Pages: 517-25
- Data Source
  KAKENHI-PROJECT-22590890
[Journal Article] The protective role of autophagy against aging and acute ischemic injury in kidney proximal tubular cells.2012
- Author(s)
  Isaka Y, Kimura T, Takabatake Y.
- Journal Title
  
  Autophagy
  
  Volume: 7 Pages: 1085-1087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659416
[Journal Article] Autophagy guards against Cisplatin-induced acute kidney injury2012
- Author(s)
  高橋篤史,松阪泰二、新村文男, 他
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 180 Pages: 517-25
- DOI
  10.1016/j.ajpath.2011.11.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249033, KAKENHI-PROJECT-22590890, KAKENHI-PROJECT-23247034, KAKENHI-PROJECT-24659416
[Journal Article] A superagonistic monoclonal antibody for CD28 ameliorates crescentic glomerulonephritis in wistar-kyoto rats2011
- Author(s)
  Takabatake Y, Li XK, Mizui M, Miyasato K, Matsui I, Kawada N, Imai E, Hunig T, Takahara S, Wada T, Furuichi K, Rakugi H, Isaka Y.
- Journal Title
  
  Mol Med
  
  Volume: 17(7-8) Pages: 686-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591030
[Journal Article] Autophagy protects the proximal tubule from degeneration and acute ischemic injury2011
- Author(s)
  Kimura T, Takabatake Y, Takahashi A, Kaimori JY, Matsui I, Namba T, Kitamura H, Niimura F, Matsusaka T, Soga T, Rakugi H, Isaka Y
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 22 Pages: 902-13
- Data Source
  KAKENHI-PROJECT-22590890
[Journal Article] CD28 superagonist-induced regulatory T cell expansion ameliorates mesangioproliferative glomerulonephritis in rats2011
- Author(s)
  Miyasato K, Takabatake Y, Kaimori J, Kimura T, Kitamura H, Kawachi H, Li XK, Hunig T, Takahara S, Rakugi H, Isaka Y.
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 15(1) Pages: 50-7
- NAID
  10029004414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591030
[Journal Article] The protective role of autophagy against aging and acute ischemic injury in kidney proximal tubular cells2011
- Author(s)
  Isaka Y., ら
- Journal Title
  
  Autophagy
  
  Volume: 7 Pages: 1085-7
- Data Source
  KAKENHI-PROJECT-22590890
[Journal Article] The protective role of autophagy against aging and acute ischemic injury in kidney proximal tubular cells2011
- Author(s)
  Isaka Y, Kimura T, Takabatake Y
- Journal Title
  
  Autophagy.
  
  Volume: 7 Pages: 1085-7
- Data Source
  KAKENHI-PROJECT-22590890
[Journal Article] Allogenic fetal membrane-derived mesenchymal stem cells contribute to renal repair in experimental glomerulonephritis2010
- Author(s)
  Tsuda H, Yamahara K, Ishikane S, Otani K, Nakamura A, Sawai K, Ichimaru N, Sada M, Taguchi A, Hododa H, Tsuji M, Kawachi H, Horio M, Isaka Y, Kangawa K, Takahara S, Ikeda T.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299 Pages: 1004-1013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591028
[Journal Article] Induction of Donor-Specific Tolerance Using Superagonistic CD28 Antibody in Rat Renal Allografts : Regulatory T-Cell Expansion Before Engraftment May Be Important2010
- Author(s)
  Azuma.H., Isaka,Y., Nomi, H., Inamoto, T., Li, XK., Hounig, T., Takabatake, Y., Ichimaru, N., Ibuki, N., Matsumoto, K., Ubai, T., Katsuoka, Y., Takahara, S.
- Journal Title
  
  Transplantation
  
  Volume: 90 Pages: 1328-1335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390446
[Journal Article] Induction of Donor-Specific Tolerance Using Superagonistic CD28 Antibody in Rat Renal Allografts : Regulatory T-Cell Expansion Before Engraftment May Be Important2010
- Author(s)
  Azuma, H., Isaka,Y., Nomi, H., Inamoto, T., Li, XK., Hőunig, T., Takabatake, Y., Ichimaru, N., Ibuki, N., Matsumoto, K., Ubai, T., Katsuoka, Y., Takahara, S.
- Journal Title
  
  Transplantation
  
  Volume: 90(12) Pages: 1328-1335
- Data Source
  KAKENHI-PROJECT-21390446
[Journal Article] Allogenic fetal membrane-derived mesenchymal stem cells contribute to renal repair in experimental glomerulonephritis.2010
- Author(s)
  Tsuda H, Yamahara K, Ishikane S.Otani K, Nakamura A, Sawai K, Ichimaru N, Sada M, Taguchi A, Hosoda H, Tsuji M, Kawachi H, Horio M, Isaka Y, Kangawa K, Takahara S, Ikeda T.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591028
[Journal Article] Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production.2009
- Author(s)
  Xie, L. ; Li, X.K. ; Funeshima-Fuji, N. ; Kimura, H. ; Matsumoto, Y. ; Isaka, Y. ; Takahara, S
- Journal Title
  
  Int Immunopharmacol 9(5)
  
  Pages: 575-581
- Data Source
  KAKENHI-PROJECT-19390414
[Journal Article] Superagonist CD28 antibody preferentially expanded Foxp3-expressing nTreg cells and prevented graft-versus-host diseases.2009
- Author(s)
  Kitazawa, Y. ; Fujino, M. ; Li, X.K. ; Xie, L. ; Ichimaru, N. ; Okumi, M. ; Nonomura, N. ; Tsujimura, A. ; Isaka, Y. ; Kimura, H. ; Hunig, T. ; Takahara, S.
- Journal Title
  
  Cell transplantation 18(5)
  
  Pages: 627-637
- Data Source
  KAKENHI-PROJECT-19390414
[Journal Article] Participation of autophagy in renal ischemia/reperfusion injury2008
- Author(s)
  Suzuki C, Isaka Y, Takabatake Y, Tanaka H, Koike M, Shibata M, Uchiyama Y, Takahara S, lmai E
- Journal Title
  
  Biochemical and biophysical research communications 368
  
  Pages: 100-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659250
[Journal Article] CD28スーパーアゴニスト抗体による制御性T細胞の誘導2008
- Author(s)
  猪阪善隆
- Journal Title
  
  臨床免疫・アレルギー科 50(4号)
  
  Pages: 451-457
- NAID
  40016324087
- Data Source
  KAKENHI-PROJECT-19390414
[Journal Article] Participation of autophagy in renal ischemial/reperfusion injury2008
- Author(s)
  Suzuki C, Isaka Y, Takabatake Y, Tanaka H, Koike M, Shibata M, Uchiyama Y, Takahara S, Imai E
- Journal Title
  
  Biochemical and biophysical research communications 368
  
  Pages: 100-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390414
[Journal Article] Nonerythropoietic derivative of erythropoietin protects against tubulointerstitialinjury in a unilateral ureteral obstruction model.2008
- Author(s)
  Kitamura H, Isaka Y, Takabatake Y. Imamura R, et al.
- Journal Title
  
  Nephrol Dial Transplant 23
  
  Pages: 1521-1528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390414
[Journal Article] Bcl-2 protects tubular epithelial cells from ischemia reperfusion injury byinhibiting apoptosis.2008
- Author(s)
  Suzuki c, Isaka Y, Shimizu s, Tsujimoto Y, et al.
- Journal Title
  
  CeU transplantation 17
  
  Pages: 223-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659250
[Journal Article] Nonerythropoietic derivative of erythropoietin protects against tubulointerstitialinjury in a unilateral ureteral obstruction model.2008
- Author(s)
  Kitamura H, Isaka Y, Takabatake Y, Imamura R, et al.
- Journal Title
  
  Nephrol Dial Transplant 23
  
  Pages: 1521-1528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659250
[Journal Article] Superagonistic CD28 antibody induces donor-specific tolerance in rat renalallografts.2008
- Author(s)
  Azuma H, Isaka Y, Li X, Hunig T, et al.
- Journal Title
  
  Am J Transplant 8
  
  Pages: 2004-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390414
[Journal Article] Superagonistic CD28 antibody induces donor-specific tolerance in rat renal allografts.2008
- Author(s)
  Azuma, H. ; Isaka, Y. Li, X. ; Hunig, T. ; Sakamoto, T. ; Nohmi, H. ; Takabatake, Y. ; Mizui, M. ; Kitazawa, Y. ; Ichimaru, N. ; Ibuki, N. ; Ubai, T. ; Inamoto, T. ; Katsuoka, Y. ; Takahara, S
- Journal Title
  
  Am J Transplant 8(10)
  
  Pages: 2004-2014
- Data Source
  KAKENHI-PROJECT-19390414
[Journal Article] Participation of autophagy in renal ischemia/reperfusion injury.2008
- Author(s)
  Suzuiki C, Isaka Y, Takabatake Y, Tanaka H, et al.
- Journal Title
  
  Biochemical and biophysical research commimications 368
  
  Pages: 100-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659250
[Journal Article] Superagonistic CD28 antibody induces donor-specific tolerance in rat renal allografts.2008
- Author(s)
  Azuma H, Isaka Y, Li X, Hunig T, Sakamoto T, Nohmi H, Takabatake Y, Mizui M, Kitazawa Y, Ichimaru N, Ibuki N, Ubai T, Inamoto T, Katsuoka Y, Takahara S.
- Journal Title
  
  Am J Transplant. 2
  
  Pages: 2004-2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659254
[Journal Article] Foxp3-expressing regulatory T cells expanded with CD28 superagonist antibody can prevent rat cardiac allograft rejection.2008
- Author(s)
  Kitazawa, Y. ; Fujino, M. ; Sakai, T. ; Azuma, H. ; Kimura, H. ; Isaka, Y. ; Takahara, S. ; Hunig, T. ; Abe, R. ; Li, X.K.
- Journal Title
  
  J Heart Lung Transplant 27(4)
  
  Pages: 362-371
- Data Source
  KAKENHI-PROJECT-19390414
[Journal Article] Carbamylated erythropoietin improves angiogenesis and protects the kidneys from ischemia-reperfusion injury.2008
- Author(s)
  Imamura R, Okumi M, Isaka Y, Ichimaru N, et al.
- Journal Title
  
  Cell transplantation 17
  
  Pages: 135-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390414
[Journal Article] Chemically modified siRNA prolonged RNA interference in renal disease2007
- Author(s)
  Takabatake, Y., Y. Isaka, M. Mizui, H. Kawachi, S. Takahara, and E. Imai.
- Journal Title
  
  Biochemical and biophysical research communications 363
  
  Pages: 432-437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390414
[Journal Article] HGF-MSP chimera protects kidneys from ischemia-reperfusion injury2007
- Author(s)
  Xue, F., Y. Isaka, T. Takahara, R. Imamura, C. Suzuki, N. Ichimaru, P. Michieli, and S. Takahara.
- Journal Title
  
  Biochemical and biophysical research communications 363
  
  Pages: 451-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390414
[Journal Article] RNAiを用いた腎疾患遺伝子治療2006
- Author(s)
  猪阪善隆, 高畠義嗣, 今井圓裕
- Journal Title
  
  分子腎臓病学-生物学的アプローチと分子病態生理学 64
  
  Pages: 659-661
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590827
[Journal Article] Electroporation-mediated HGF gene transfection protected the kidney against graft iniury.2006
- Author(s)
  Isaka Y, Yamada K, Takabatake Y, et al.
- Journal Title
  
  Gene Therapy 12
  
  Pages: 815-820
- Data Source
  KAKENHI-PROJECT-17590827
[Journal Article] Bcl-2 protects tubular epithelial cells from ischemia reperfusion injury via dual mechanism2006
- Author(s)
  Suzuki C, Isaka Y, et al.
- Journal Title
  
  J Am Soc Nephrol 17
- Data Source
  KAKENHI-PROJECT-18659250
[Journal Article] 腎疾患の遺伝子治療2006
- Author(s)
  猪阪善隆
- Journal Title
  
  医学のあゆみ 216
  
  Pages: 771-774
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590827
[Journal Article] Exploring RNA interference as a therapeutic strategy for renal disease.2006
- Author(s)
  Takabatake Y, Isaka Y, Mizui M, et al.
- Journal Title
  
  Gene Therapy 12
  
  Pages: 965-973
- Data Source
  KAKENHI-PROJECT-17590827
[Journal Article] Gene Therapy Targeting Kidney Diseases ; Routes ＆ Vehicles.2006
- Author(s)
  Isaka Y
- Journal Title
  
  Clin Exp Nephrol 10
  
  Pages: 229-235
- NAID
  10020572665
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590827
[Journal Article] RNAi創薬と腎疾患2006
- Author(s)
  猪阪善隆
- Journal Title
  
  医学のあゆみ 216
  
  Pages: 848-848
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590827
[Journal Article] RNAiを用いた腎疾患遺伝子治療2006
- Author(s)
  猪阪善隆, 高畠義嗣, 今井圓裕
- Journal Title
  
  分子腎臓病学-生物学的アプロ-チと分子病態生理学 64
  
  Pages: 659-661
- Data Source
  KAKENHI-PROJECT-17590827
[Journal Article] Gene Therapy Targeting Kidney Diseases : Routes ＆ Vehicles2006
- Author(s)
  Y Isaka
- Journal Title
  
  Clin Exp Nephrol 10
  
  Pages: 229-235
- NAID
  10020572665
- Data Source
  KAKENHI-PROJECT-17590827
[Journal Article] Gene Therapy Targeting Kidney Diseases; Routes ＆ Vehicles2006
- Author(s)
  Y Isaka
- Journal Title
  
  Clin Exp Nephrol 10
  
  Pages: 229-235
- NAID
  10020572665
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590827
[Journal Article] ポストゲノム時代の腎臓病研究2004
- Author(s)
  今井圓裕, 伊藤孝仁, 猪阪善隆
- Journal Title
  
  日本内科学会誌 93
  
  Pages: 168-175
- NAID
  10012881173
- Data Source
  KAKENHI-PROJECT-15390270
[Presentation] 脂質代謝異常によるリソソーム障害が急性腎障害（AKI）を進展させる2020
- Author(s)
  中村隼、南聡、山本毅士、高畠義嗣、難波倫子、高橋篤史、余西洋明、猪阪善隆
- Organizer
  第63回日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08677
[Presentation] Cloud Share System to promote regional collaboration in CAPD patients.2019
- Author(s)
  Isaka Y.
- Organizer
  The 9th Asia Pacific Chapter Meeting of International Society for Peritoneal Dialysis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10558
[Presentation] Peer-to-peer network : a key healthcare approach to increase resilience in PD patients.2019
- Author(s)
  Kitamura H, Nakajima K, Isaka Y.
- Organizer
  The 9th Asia Pacific Chapter Meeting of International Society for Peritoneal Dialysis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10558
[Presentation] オートファジーからみた慢性腎臓病治療の新しい知見2018
- Author(s)
  猪阪善隆
- Organizer
  7.第61回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04188
[Presentation] MCKD1の発症には変異MUC1遺伝子に対するナンセンス変異依存mRNA分解機構の破綻と小胞体ストレスが関与している2017
- Author(s)
  山本聡子, 貝森淳哉, 高原史郎, 猪阪善隆
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09615
[Presentation] 糖尿病性腎症の存在下でも可能な、DTI MRIによる腎線維化撮影法の確立2017
- Author(s)
  貝森淳哉，猪阪善隆，余川隆, 市丸直嗣，高原史郎
- Organizer
  第43回日本移植学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10640
[Presentation] High Fat Diet-Induced Lysosomal Dysfunction and Impaired Autophagic Flux Contribute to the Lipotoxicity in the Kidney2016
- Author(s)
  Yamamoto T, Takabatake Y, Takahashi A, Kimura T, Namba T, Matsuda J, Minami S, Matsusaka T, Niimura F, Yanagita M, Isaka Y.
- Organizer
  American Society of Nephrology Kidney Week 2016
- Place of Presentation
  シカゴ, アメリカ
- Year and Date
  2016-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09260
[Presentation] Lipophagy Maintains Energy Homeostasis during Prolonged Starvation in the Kidney Proximal Tubule2016
- Author(s)
  Minami S, Yamamoto T, Takabatake Y, Takahashi A, Namba T, Matsuda J, Matsusaka T, Niimura F, Isaka Y.
- Organizer
  American Society of Nephrology Kidney Week 2016
- Place of Presentation
  シカゴ, アメリカ
- Year and Date
  2016-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09260
[Presentation] 膜性腎症の治療：JNSCS研究から見えてくるもの2016
- Author(s)
  山本陵平 (大阪大学保健センター)、横山仁 (金沢医科大学腎臓内科学)、今井圓裕 (中山寺いまいクリニック)、丸山彰一 (名古屋大学腎臓内科学)、猪阪善隆 (大阪大学腎臓内科学)
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-06-19
- Data Source
  KAKENHI-PROJECT-16H05839
[Presentation] 過剰の25-hydroxyvitamin D (25D)はマクロファージの表現型を変化させることで尿細管間質障害を悪化させる2015
- Author(s)
  楠康生　松井功　濱野高行　下村明弘　森大輔　米本佐代子　椿原美治　樂木宏実　猪阪善隆
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-26461227
[Presentation] オートファジーとミトファジー2014
- Author(s)
  猪阪善隆
- Organizer
  抗加齢医学会
- Place of Presentation
  大阪
- Year and Date
  2014-06-06
- Invited
- Data Source
  KAKENHI-PROJECT-24659416
[Presentation] 慢性腎臓病におけるオートファジーと慢性炎症の接点2014
- Author(s)
  猪阪善隆
- Organizer
  腎不全研究会
- Place of Presentation
  東京
- Year and Date
  2014-12-13
- Invited
- Data Source
  KAKENHI-PROJECT-24659416
[Presentation] オートファジーとミトファジー2014
- Author(s)
  猪阪善隆
- Organizer
  第14回日本抗加齢医学会総会
- Place of Presentation
  大阪
- Year and Date
  2014-06-06
- Invited
- Data Source
  KAKENHI-PROJECT-24591196
[Presentation] 新規エピゲノムマーカーとしてのH4K20アセチル化2013
- Author(s)
  猪阪善隆
- Organizer
  日本腎臓学会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25670410
[Presentation] ループス腎炎モデルマウスに対するCD28スーパーアゴニストの治療効果の検証2010
- Author(s)
  高畠義嗣、木村友則、宮里研郎、高橋篤史、植畑拓也、貝森淳哉、川田典孝、今井圓裕、HunigThomas、李小康、楽木宏実、猪阪善隆
- Organizer
  日本腎臓学会第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21591030
[Presentation] Successful induction of donor-specific tolerance using Super-agonistic CD28 antibody in rat renal allografts2010
- Author(s)
  Azuma, H., Nomi, H., Ibuki, N., Inamoto, T., Isaka, Y., Takahara, S., Katsuoka, Y.
- Organizer
  XXII International Congress of The Transplantation Society
- Place of Presentation
  Vancouver Convention Center (Canada)
- Year and Date
  2010-08-18
- Data Source
  KAKENHI-PROJECT-21390446
[Presentation] Systemic administration of siRNA targeting p53 protects kidneys from ischemia-reperfusion injury in experimental rat kidney transplantation model.2008
- Author(s)
  Isaka Y
- Organizer
  American Society of Nephrology
- Place of Presentation
  Philadelphia
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-19390414
[Presentation] Systemic administration of siRNA targeting p53 protects kidneys from ischemia-reperfusion injury in experimental rat kidney transplantation model.2008
- Author(s)
  Isaka Y
- Organizer
  American Society of Nephrology
- Place of Presentation
  Philadelphia
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-20659250
[Presentation] Donor specific tolerance induced bySuperagonistic CD28 antibody in rat renal allografts2008
- Author(s)
  Azuma H, Isaka Y, Li X, Hunig T, Nohmi H, Takabatake Y, Mizui M, Kitazawa Y, Ichimaru N, Ibuki N, Ubai T, Inamoto T, Katsuoka Y, Takahara.
- Organizer
  The 7^<th> Korea-Japan Transplantation Forum
- Place of Presentation
  Soul, Korea
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-20659254
[Presentation] A superagonistic monoclonal antibody for CD28 induced donor-specific tolerance2007
- Author(s)
  Y Isaka, Y Takabatake, M Mizui, H Tanaka, X Li, H Azuma, T Hunig, R Imamura, N Ichimaru, E Imai, S Takahara
- Organizer
  American Society of Nephrology
- Place of Presentation
  San Francisco USA
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-19390414
[Presentation] A Superagonistic Monoclonal Antibody for CD28 Induced Donor-Specific Tolerance.2007
- Author(s)
  Isaka Y
- Organizer
  American Society of Nephrology
- Place of Presentation
  San Francisco
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-19390414

1. TAKABATAKE Yoshitsugu (30403075)

# of Collaborated Projects: 13 results

# of Collaborated Products: 27 results
2. TAKAHARA Shiro (70179547)

# of Collaborated Projects: 11 results

# of Collaborated Products: 25 results
3. KAIMORI Jyun-ya (70527697)

# of Collaborated Projects: 6 results

# of Collaborated Products: 11 results
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# of Collaborated Projects: 5 results

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5. Takahashi Atsushi (10704786)

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# of Collaborated Products: 8 results
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# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
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# of Collaborated Products: 9 results
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isaka yoshitaka 猪阪 善隆

ISAKA Yoshitaka 猪阪 善隆

猪阪 喜隆 イサカ ヨシタカ

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早期CKD患者の精密医療を目指した予後評価法の開発Principal Investigator

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Elucidation of renal disease onset and progression mechanism using single cell RNA-sequencePrincipal Investigator

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Development of a new therapy for lifestyle-related CKD targeting autophagy recycling systemPrincipal Investigator

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isaka yoshitaka 猪阪善隆

ISAKA Yoshitaka 猪阪善隆

猪阪喜隆イサカヨシタカ