NOMA KENSUKE 野間玄督

Researcher Number	00379893
Affiliation (based on the past Project Information) *help	2019: 広島大学, 原爆放射線医科学研究所, 専門研究員 2011 – 2018: 広島大学, 原爆放射線医科学研究所, 助教
Review Section/Research Field	Principal Investigator Cardiovascular medicine / Circulatory organs internal medicine Except Principal Investigator Cardiovascular surgery / Kidney internal medicine / Emergency medicine
Keywords	Principal Investigator 心血管障害 / ROCK / 糖尿病 / 国際情報交流　米国 / 血管内皮機能 / 老化 / 血管障害 / ストレス誘導性細胞老化 / 米国 / 国際情報交流 … More / 臨床 / 発現制御 / 循環器・高血圧 / シグナル伝達 / トランスレーショナルリサーチ / eNOS / 血管機能 / 脳梗塞 … More Except Principal Investigator 抗炎症作用 / 線維化 / 大血管外科学 / 抗アポトーシス作用 / 無血清培地 / アポトーシス / 微重力培養 / 抗炎症性 / 虚血性脊髄障害 / 間葉系幹細胞 / 脊髄虚血 / 腎線維化 / 高血圧 / 糖尿病性腎症 / 腎硬化症 / 超音波療法 / 循環器・高血圧 / 再生医学 / 心筋虚血モデル / 再生療法 / 細胞バンク / 再生医療 / 緊急被ばく医療 Less

Role of ROCK in stress-induced cellular senecesense on diabetes: from bench to bedsidePrincipal Investigator
- Principal Investigator
  
  NOMA KENSUKE
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Hiroshima University
Mesenchymal stem cell with anti-inflammatory effect cultured under microgravity prevents paraplegia after thoracic aortic repair
- Principal Investigator
  
  Takahashi Shinya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Hiroshima University
ROCK蛋白阻害剤と微小重力下で培養した幹細胞による心筋の保護と再生
- Principal Investigator
  
  田口隆浩
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Hiroshima University
Low-Intensity Pulsed Ultrasound Ameliorates Experimental Renal Fibrosis
- Principal Investigator
  
  Nakashima Ayumu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hiroshima University
Role of ROCK in diabetes-mediated cardiovascular disease: from bench to bedsidePrincipal Investigator
- Principal Investigator
  
  NOMA KENSUKE
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Hiroshima University
Construction of medicine for radiation emergency system using iPS cell bank
- Principal Investigator
  
  Higashi Yukihito
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Emergency medicine
- Research Institution
  Hiroshima University
Role of ROCK activity in cardiovascular diseases: a translational researchPrincipal Investigator
- Principal Investigator
  
  NOMA KENSUKE
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Hiroshima University

All 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] ICU看護実践ハンドブック2013
- Author(s)
  野間玄督，東　幸仁
- Total Pages
  4
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23591043
[Book] 糖尿病と酸化ストレス2011
- Author(s)
  野間玄督, 東幸仁
- Total Pages
  5
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Combination of Flow-Mediated Vasodilation and Nitroglycerine-Induced Vasodilation Is More Effective for Prediction of Cardiovascular Events.2016
- Author(s)
  Kajikawa M, Maruhashi T, Hida E, Iwamoto Y, Matsumoto T, Iwamoto A, Oda N,Kishimoto S, Matsui S, Hidaka T, Kihara Y, Chayama K, Goto C, Aibara Y, Nakashima A, Noma K, Higashi Y.
- Journal Title
  
  Hypertension
  
  Volume: 67(5) Issue: 5 Pages: 1045-52
- DOI
  10.1161/hypertensionaha.115.06839
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-25670762
[Journal Article] Ratio of serum levels of AGEs to soluble form of RAGE is a predictor of endothelial function.2015
- Author(s)
  Kajikawa M, Nakashima A, Fujimura N, Maruhashi T, Iwamoto Y, Iwamoto A, Matsumoto T, Oda N, Hidaka T, Kihara Y, Chayama K, Goto C, Aibara Y, Noma K, Takeuchi M, Matsui T, Yamagishi S, Higashi Y.
- Journal Title
  
  Diabetes Care.
  
  Volume: 38(1) Issue: 1 Pages: 119-25
- DOI
  10.2337/dc14-1435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591055, KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-25670762
[Journal Article] Exogenous nitric oxide inhibits Rho-associated kinase activity in patients with angina pectoris: a randomized controlled trial.2015
- Author(s)
  Maruhashi T, Noma K, Fujimura N, Kajikawa M, Matsumoto T, Hidaka T, Nakashima A, Kihara Y, Liao JK, Higashi Y.
- Journal Title
  
  Hypertens Res.
  
  Volume: 38(7) Issue: 7 Pages: 485-90
- DOI
  10.1038/hr.2015.24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-25670762
[Journal Article] Rho-associated kinase activity is an independent predictor of cardiovascular events in acute coronary syndrome.2015
- Author(s)
  Kajikawa M, Noma K, Nakashima A, Maruhashi T, Iwamoto Y, Matsumoto T, Iwamoto A, Oda N, Hidaka T, Kihara Y, Aibara Y, Chayama K, Sasaki S, Kato M, Dote K, Goto C, Liao JK, Higashi Y.
- Journal Title
  
  Hypertension.
  
  Volume: 66(4) Issue: 4 Pages: 892-9
- DOI
  10.1161/hypertensionaha.115.05587
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-25670762
[Journal Article] Effect of aldosterone-producing adenoma on endothelial function and Rho-associated kinase activity in patients with primary aldosteronism.2015
- Author(s)
  Matsumoto T, Oki K, Kajikawa M, Nakashima A, Maruhashi T, Iwamoto Y, Iwamoto A, Oda N, Hidaka T, Kihara Y, Kohno N, Chayama K, Goto C, Aibara Y, Noma K, Liao JK, Higashi Y.
- Journal Title
  
  Hypertension.
  
  Volume: 65(4) Issue: 4 Pages: 841-8
- DOI
  10.1161/hypertensionaha.114.05001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09084, KAKENHI-PROJECT-25670762
[Journal Article] Borderline ankle-brachial index value of 0.91 to 0.99 is associated with endothelial dysfunction.2014
- Author(s)
  Kajikawa M, Maruhashi T, Iwamoto Y, Iwamoto A, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Nakashima A, Goto C, Noma K, Higashi Y.
- Journal Title
  
  Circ J.
  
  Volume: 78 Pages: 1740-1745
- NAID
  130004926966
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670762
[Journal Article] Critical role of exogenous nitric oxide in ROCK activity in vascular smooth muscle cells.2014
- Author(s)
  Maruhashi T, Noma K, Fujimura N, Idei, N, Mikami S, Iwamoto Y, Kajikawa M, Matsumoto T, Hidaka T, Goto C, Kihara Y, Chayama K, Liao JK, Higashi Y.
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 10 Pages: e109017-e109017
- DOI
  10.1371/journal.pone.0109017
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670762
[Journal Article] Oxidative stress and endothelial dysfunction: clinical evidence and therapeutic implications.2014
- Author(s)
  Higashi Y, Maruhashi T, Noma K, Kihara Y.
- Journal Title
  
  Trends Cardiovasc Med.
  
  Volume: 24(4) Issue: 4 Pages: 165-9
- DOI
  10.1016/j.tcm.2013.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591055, KAKENHI-PROJECT-25670762
[Journal Article] Poor oral health behavior, decreased frequency of tooth brushing, is associated with endothelial dysfunction.2014
- Author(s)
  Kajikawa M, Maruhashi T, Iwamoto Y, Iwamoto A, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Nakashima A, Goto C, Noma K, Taguchi A, Higashi Y.
- Journal Title
  
  Circ J.
  
  Volume: 78 Pages: 950-954
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670762
[Journal Article] Relationship between nitroglycerine-induced vasodilation and clinical severity of peripheral arterial disease.2014
- Author(s)
  Maruhashi T, Nakashima A, Matsumoto T, Oda N, Iwamoto Y, Iwamoto A, Kajikawa M, Kihara Y, Chayama K, Goto C, Noma K, Higashi Y.
- Journal Title
  
  Atherosclerosis.
  
  Volume: 235 Issue: 1 Pages: 65-70
- DOI
  10.1016/j.atherosclerosis.2014.04.012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670762
[Journal Article] Rho-associated kinase is a predictor of a predictor of cardiovascular outcomes.2013
- Author(s)
  Kajikawa M, Noma K, Maruhashi T, Mikami S, Iwamoto Y, Iwamoto A, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Nakashima A, Goto C, Liao JK, Higashi Y.
- Journal Title
  
  Hypertension.
  
  Volume: 64 Issue: 4 Pages: 856-864
- DOI
  10.1161/hypertensionaha.113.02296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591043, KAKENHI-PROJECT-24591055, KAKENHI-PROJECT-25670762
[Journal Article] FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2.2013
- Author(s)
  Noma K, Okamoto R, Li Y, Hiroi Y, Liu PY, Taniguchi M, Ito M, Liao JK.
- Journal Title
  
  FASEB J
  
  Volume: 27 Pages: 1439-1449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Relationship between flow-mediated vasodilation and cardiovascular risk factors in a large community-based study.2013
- Author(s)
  Maruhashi T, Soga J, Fujimura N, Idei N, Mikami S, Iwamoto Y, Kajikawa M, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Noma K, Nakashima A, Goto C, Tomiyama H, Takase B, Yamashina A, Higashi Y.
- Journal Title
  
  Heart
  
  Volume: 99(24) Issue: 24 Pages: 1837-1842
- DOI
  10.1136/heartjnl-2013-304739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591081, KAKENHI-PROJECT-25670762
[Journal Article] Hyperuricemia is independently associated with endothelial dysfunction in postmenopausal women but not in premenopausal women.2013
- Author(s)
  Maruhashi T, Nakashima A, Soga J, Fujimura N, Idei N, Mikami S, Iwamoto Y, Kajikawa M, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Goto C, Noma K, Tomiyama H, Takase B, Yamashina A, Higashi Y.
- Journal Title
  
  BMJ Open
  
  Volume: 2013 Nov 8;3(11) Issue: 11 Pages: e003659-e003659
- DOI
  10.1136/bmjopen-2013-003659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591081, KAKENHI-PROJECT-25670762
[Journal Article] Nitroglycerine-induced Vasodilation for Assessment of Vascular Function: A Comparison with Flow-mediated Vasodilation.2013
- Author(s)
  Maruhashi T, Soga J, Idei N, Fujimura N, Mikami S, Iwamoto Y, Kajikawa M, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Noma K, Nakashima A, Goto C, Higashi Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 33 Issue: 6 Pages: 1401-1408
- DOI
  10.1161/atvbaha.112.300934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670762
[Journal Article] FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2.2013
- Author(s)
  Noma K, Okamoto R, Li Y, Hiroi Y, Liu PY, Taniguchi M, Ito M, Liao JK.
- Journal Title
  
  FASEB J.
  
  Volume: 27 Issue: 4 Pages: 1439-1449
- DOI
  10.1096/fj.12-217018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043, KAKENHI-PROJECT-23790883, KAKENHI-PROJECT-24591113
[Journal Article] Flow-mediated vasodilation and anatomical variation of brachial artery (double brachial artery) in healthy subjects and atherosclerotic patients.2013
- Author(s)
  Fujii Y, Teragawa H, Soga J, Fujimura N, Idei N, Hidaka T, Hata T, Mikami S, Maruhashi T, Iwamoto Y, Kihara Y, Chayama K, Noma K, Nakashima A, Goto C, Higashi Y.
- Journal Title
  
  Circ J
  
  Volume: 77 Pages: 1073-1080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670762
[Journal Article] Nitroglycerine-induced Vasodilation for Assessment of Vascular Function: A Comparison with Flow-mediated Vasodilation.2013
- Author(s)
  Maruhashi T, Soga J, Fujimura N, Idei N, Mikami S, Iwamoto Y, Kajikawa M, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Noma K, Nakashima A, Goto C, Higashi Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] A Novel Noninvasive and Simple Method for Assessment of Endothelial Function:Enclosed Zone Flow-Mediated Vasodilation (ezFMD) Using an Oscillation Amplitude Measurement.2013
- Author(s)
  Idei N, Ukawa T, Kajikawa M, Iwamoto Y, Fujimura N, Maruhashi T, Mikami S, Matsumoto T, Kihara Y, Chayama K, Noma K, Nakashima A, Takayanagi T, Morimoto H, Tsuji T, Higashi Y.
- Journal Title
  
  Circ J
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Rho-associated kinase is a predictor of a predictor of cardiovascular outcomes2013
- Author(s)
  Kajikawa M, Noma K, Maruhashi T, Mikami S, Iwamoto Y, Iwamoto A, Matsumoto T, Hidaka T, Kihara Y, Chayama K, Nakashima A, Goto C, Liao JK, Higashi Y.
- Journal Title
  
  Hypertension
  
  Volume: 64 Pages: 856-864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Impact of aldosterone-producing adenoma on cardiac structures in echocardiography.2013
- Author(s)
  Hidaka T, Shiwa T, Fujii Y, Nishioka K, Utsunomiya H, Ishibashi K, Mitsuba N, Dohi Y, Oda N, Noma K, Kurisu S, Nakano Y, Yamamoto H, Ishida T, Higashi Y, Kihara Y.
- Journal Title
  
  J Echocardiogr.
  
  Volume: 24 Pages: 185-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670762
[Journal Article] Autologous Bone-Marrow Mesenchymal Stem Cell Implantation and Endothelial Function in a Rabbit Ischemic Limb Model2013
- Author(s)
  Mikami S, Nakashima A, Nakagawa K, Maruhashi T, Iwamoto Y, Kajikawa M, Matsumoto T, Kihara Y, Chayama K, Noma K, Ochi M, Nishimura M, Tsuji K, Kato Y, Goto C, Higashi Y
- Journal Title
  
  PLOS ONE
  
  Volume: 8(7) Issue: 7 Pages: e67739-e67739
- DOI
  10.1371/journal.pone.0067739
- NAID
  120006986197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390423, KAKENHI-PROJECT-24659876, KAKENHI-PROJECT-25670369, KAKENHI-PROJECT-25670762
[Journal Article] Flow-Mediated Vasodilation and Anatomical Variation of the Brachial Artery (Double Brachial Artery) in Healthy Subjects and Patients with Cardiovascular Diseases.2013
- Author(s)
  Fujii Y, Teragawa H, Soga J, Idei N, Fujimura N, Maruhashi T, Mikami S, Iwamoto Y, Hidaka T, Kihara Y, Chayama K, Noma K, Nakashima A, Goto C, Higashi Y.
- Journal Title
  
  Circ J
  
  Volume: 77 Pages: 1073-1080
- NAID
  10031139013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Mineralocorticoid Receptor Blocker Eplerenone Improves Endothelial Function and Inhibits Rho-associated Kinase Activity in Patients With Hypertension2012
- Author(s)
  Fujimura N, Noma K, Hata T, Soga J, Hidaka T, Idei N, Fujii Y, Mikami S, Maruhashi T, Iwamoto Y, Kihara Y, Chayama K, Kato H, Liao JK, Higashi Y.
- Journal Title
  
  Clin Pharmacol Ther
  
  Volume: 91 Issue: 2 Pages: 289-297
- DOI
  10.1038/clpt.2011.227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Hyperbilirubinemia, Augmentation of Endothelial Function and Decrease in Oxidative Stress in Gilbert Syndrome.2012
- Author(s)
  Maruhashi T, Soga J, Fujimura N, Idei N, Mikami S, Iwamoto Y, Kajikawa M, Matsumoto T, Kihara Y, Chayama K, Noma K, Nakashima A, Tomiyama H, Takase B, Yamashina A, Higashi Y.
- Journal Title
  
  Circulation
  
  Volume: 126 Issue: 5 Pages: 598-603
- DOI
  10.1161/circulationaha.112.105775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043, KAKENHI-PROJECT-24591055, KAKENHI-PROJECT-24591081
[Journal Article] Geranylgeranylacetone, Hsp90/AMPK/eNOS/NO Pathway, and Endothelial Function in Humans.2012
- Author(s)
  Fujimura N, Jitsuiki D, Maruhashi T, Mikami S, Iwamoto Y, Kajikawa M, Chayama K, Kihara Y, Noma K, Goto C, Higashi Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 32 Pages: 153-160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Intima-Media Thickness of Brachial Artery, Vascular Function, and Cardiovascular Risk Factors.2012
- Author(s)
  Iwamoto Y, Maruhash T, Fujii Y, Idei N, Fujimura N, Mikami S, Kajikawa M, Matsumoto T, Kihara Y, Chayama K, Noma K, Nakashima A, Higashi Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 32 Issue: 9 Pages: 2295-2303
- DOI
  10.1161/atvbaha.112.249680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043, KAKENHI-PROJECT-24591055, KAKENHI-PROJECT-24592849
[Journal Article] Striking Crosstalk of ROCK Signaling with Endothelial Function2012
- Author(s)
  Noma K, Kihara Y, Higashi Y.
- Journal Title
  
  J Cardiol
  
  Volume: 60 Pages: 1-6
- NAID
  10031187760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] How to Use Ezetimibe as an Anti-Atherogenic Agent via Inhibition of Rho-Kinase2012
- Author(s)
  Noma K, Higashi Y.
- Journal Title
  
  Circ J
  
  Volume: 76 Pages: 1836-1837
- NAID
  10030504234
- URL
  https://www.jstage.jst.go.jp/browse/circj/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Notch1 in Bone Marrow-derived Cells Mediates Cardiac Repair Following Myocardial Infarction.2011
- Author(s)
  Li Y, Hiroi Y, Ngoy S, Okamoto R, Noma K, Wang CY, Wang HW, Zhou Q, Radtke F, Liao R, Liao JK.
- Journal Title
  
  Circulation
  
  Volume: 123 Pages: 866-876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Color Doppler Flows of Corkscrew Collaterals in Thromboangiitis Obliterans (Buerger's Disease) Using Color Duplex Ultrasonography.2011
- Author(s)
  Fujii Y, Soga J, Hidaka T, Hata T, Idei N, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Noma K, Higashi Y.
- Journal Title
  
  J Am Coll Cardiol
  
  Volume: 57 Pages: 2539-2539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Flow-mediated vasodilation is augmented in a corkscrew collateral artery compared with that in a native artery in patients with thromboangiitis obliterans (Buerger disease).2011
- Author(s)
  Fujii Y, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Chayama K, Noma K, Higashi Y.
- Journal Title
  
  J Vasc Surg
  
  Volume: 54 Pages: 1689-1697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Autologous Bone-Marrow Mononuclear Cell Implantation Reduces Long-Term Major Amputation Risk in Patients with Critical Limb Ischemia: A Comparison of Atherosclerotic Peripheral Arterial Disease and Buerger's Disease.2011
- Author(s)
  Idei N, Soga J, Hata T, Fujii Y, Mikami S, Maruhashi T, Nishioka K, Hidaka T, Kihara Y, Chowdfury M, Noma K, Taguchi A, Chayama K, Sueda T, Higashi Y.
- Journal Title
  
  Circ Cardiovasc Interv
  
  Volume: 4 Pages: 15-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Vascular Function and Circulating Progenitor Cells in Thromboangitis Obliterans (Buerger’s Disease) and Atherosclerosis Obliterans.2011
- Author(s)
  Idei N, Nishioka K, Soga J, Hidaka T, Hata T, Fujii Y, Fujimura N, Maruhashi T, Mikami S, Teragawa H, Kihara Y, Noma K, Chayama K, Higashi Y.
- Journal Title
  
  Hypertension
  
  Volume: 57 Pages: 70-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] Role of Rho kinase isoforms in Murine Allergic Airway Responses.2011
- Author(s)
  Zhu M, Liu PY, Kasahara DI, Williams AS, Verbout NG, Halayko AJ, Fedulov A, Shoji T, Williams ES, Noma K, Shore SA, Liao JK.
- Journal Title
  
  Eur Respir J
  
  Volume: 38 Pages: 841-850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Journal Article] ROCK Study Group. Rho-associated kinase activity, endothelial function, and cardiovascular risk factors2011
- Author(s)
  Higashi Y(14人中14番目)
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31 Issue: 10 Pages: 2353-9
- DOI
  10.1161/atvbaha.111.227892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592404, KAKENHI-PROJECT-23591043
[Journal Article] Rho-Associated Kinase (ROCK) Activity, Endothelial Function and Cardiovascular Risk Factors.2011
- Author(s)
  Soga J, Noma K, Hata T, Hidaka T, Fujii Y, Idei N, Fujimura N, Mikami S, Maruhashi T, Kihara Y, Chayama K, MD, Kato H, Liao JK, Higashi Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31 Pages: 2353-2359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] 脳心血管障害の予測因子としてのROCK活性2017
- Author(s)
  野間玄督、梶川正人、木原康樹、東幸仁
- Organizer
  第49回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09554
[Presentation] ROCK蛋白から斬った動脈硬化症：トランスレーショナル研究2016
- Author(s)
  野間玄督、丸橋達也、木原康樹、東幸仁
- Organizer
  日本薬理学会
- Place of Presentation
  神奈川 (横浜)
- Year and Date
  2016-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-26461110
[Presentation] ROCKをターゲットとした心肥大 / 心疾患における治療戦略2016
- Author(s)
  野間玄督、木原康樹、東幸仁
- Organizer
  第2回J-ISCP (国際心血管薬物療法学会　日本部会)
- Place of Presentation
  徳島
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461110
[Presentation] 外因性NOはROCK活性の抑制を介して心血管疾患を制御する：トランスレーショナル研究2015
- Author(s)
  野間玄督、丸橋達也、木原康樹、東幸仁
- Organizer
  第51回高血圧関連疾患モデル学会
- Place of Presentation
  大阪
- Year and Date
  2015-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-26461110
[Presentation] ROCK Activity and Endothelial Function: Potential Candidates for Vascular and Anti-aging Biomarkers2014
- Author(s)
  野間玄督, 木原康樹, 東　幸仁.
- Organizer
  第14回日本抗加齢医学会総会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Destabilization of eNOS mRNA via ROCK2-mediated eEF1A1 phospohrylation2014
- Author(s)
  野間玄督,木原康樹,東幸仁
- Organizer
  第3回臨床高血圧フォーラム
- Place of Presentation
  広島,日本
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] ROCK as a modulator of sustained vasoconstriction of resistance artery in patients with essential hypertension2014
- Author(s)
  Noma K, Goto C, Kihara Y, Liao JK, Higashi Y.
- Organizer
  第78回日本循環器学会総会・学術集会
- Place of Presentation
  東京,日本
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] ROCK as a Modulator of Sustained Vasoconstriction of ResistanceArtery in Patients with Essential Hypertension.2014
- Author(s)
  Noma K, Goto C, Kihara Y, Liao JK, Higashi Y.
- Organizer
  第78回日本循環器学会総会・学術集会.
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Role of ROCK in sustained vasoconstriction in patients with essential hypertension2014
- Author(s)
  Noma K, Goto C, Kihara Y, Liao JK, Higashi Y.
- Organizer
  The 18^<th> International Vascular Biology Meeting (IVBM2014)
- Place of Presentation
  京都,日本
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Destabilization of eNOS mRNA via ROCK2-mediated eEF1A1 phosphorylation.2014
- Author(s)
  野間玄督, 木原康樹, 東　幸仁.
- Organizer
  第3回臨床高血圧フォーラム
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Role of ROCK in Sustained Arterial Vasoconstriction in Patients with Essential Hypertension.2014
- Author(s)
  Noma K, Goto C, Kihara Y, Liao JK, Higashi Y.
- Organizer
  The 18th International Vascular Biology Meeting (IVBM 2014)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Clinical Impact of ROCK in Sustained Vasoconstriction in Patients with Essential Hypertension.2014
- Author(s)
  Noma K, Goto C, Kihara Y, Higashi Y.
- Organizer
  第35回日本循環制御医学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Clinical Evaluation of Endothelial Function and Dysfunction2013
- Author(s)
  野間玄督, 木原康樹, 東　幸仁.
- Organizer
  第35回EMBC学術集会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Regulation of eNOS mRNA stability via ROCK2-mediated eEF1A1 phosphorylation2013
- Author(s)
  野間玄督、木原康樹、東幸仁
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  大阪,日本
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Regulation of eNOS mRNA stability via ROCK2-mediated eEF1A1 phosphorylation.2013
- Author(s)
  野間玄督、木原康樹、東幸仁
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Role of ROCK in sustained vasoconstriction of resistance artery in patients with essential hypertension2013
- Author(s)
  Noma K, Goto C, Kihara Y, Liao JK, Higashi Y.
- Organizer
  Scientific Sessions 2013, American Heart Association
- Place of Presentation
  Dallas, USA
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Role of ROCK in Sustained Vasoconstriction of Resistance Artery in Patients with Essential Hypertension.2013
- Author(s)
  Noma K, Goto C, Kihara Y, Liao JK, Higashi Y.
- Organizer
  Scientific Sessions 2013, American Heart Association.
- Place of Presentation
  Dallas, USA
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] ROCK関連研究の新たな展開2012
- Author(s)
  野間玄督,東幸仁
- Organizer
  第41回日本心脈管作動物質学会
- Place of Presentation
  秋田,日本
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] ROCK関連研究の新たな展開2012
- Author(s)
  野間玄督, 東幸仁
- Organizer
  第41回日本心脈管作動物質学会(招待講演)
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Role of ROCK in sustained vasoconstriction in patients with essential hypertension.2012
- Author(s)
  野間玄督, 東幸仁
- Organizer
  第8回宮崎サイエンスキャンプ
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] 心血管疾患におけるROCK活性：メディエーターそしてマーカーとしての役割2011
- Author(s)
  野間玄督, 東幸仁, 木原康樹
- Organizer
  第19回日本血管生物医学会学術集会(招待講演)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Leukocyte ROCK Activity: a Potential Candidate for Vascular and Anti-aging Biomarker.2011
- Author(s)
  野間玄督, 木原康樹, 東幸仁
- Organizer
  アンチエイジングフェスタ2011
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] 心血管疾患におけるROCK活性:メディエーターそしてマーカーとしての役割2011
- Author(s)
  野間玄督,東幸仁,木原康樹
- Organizer
  第19回日本血管生物医学会学術集会
- Place of Presentation
  東京,日本
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Leukocyte ROCK activity : a potential candidate for vascular and anti-aging biomarker2011
- Author(s)
  野間玄督,木原康樹,東幸仁
- Organizer
  アンチエイジングフェスタ2011
- Place of Presentation
  大阪,日本
- Data Source
  KAKENHI-PROJECT-23591043
[Presentation] Regulation of eNOS mRNA stability vie ROCK2-mediated phosphorylation of eEF1A
- Author(s)
  野間玄督，廣井透雄，James K. Liao、，東　幸仁
- Organizer
  第9回宮崎サイエンスキャンプ
- Place of Presentation
  宮崎
- Invited
- Data Source
  KAKENHI-PROJECT-23591043

1. HIGASHI Yukihito (40346490)

# of Collaborated Projects: 5 results

# of Collaborated Products: 55 results
2. NAKASHIMA AYUMU (40448262)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
3. Takahashi Shinya (70423382)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 田口隆浩 (70772010)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 末田泰二郎 (10162835)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 弓削類 (20263676)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 正木崇生 (30397913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. AIBARA Yoshiki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Liao James K.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 木原康樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
11. 高瀬凡平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 加藤幸夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NOMA KENSUKE 野間 玄督

Research Projects

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Co-Researchers

Role of ROCK in stress-induced cellular senecesense on diabetes: from bench to bedsidePrincipal Investigator

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Mesenchymal stem cell with anti-inflammatory effect cultured under microgravity prevents paraplegia after thoracic aortic repair

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ROCK蛋白阻害剤と微小重力下で培養した幹細胞による心筋の保護と再生

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Low-Intensity Pulsed Ultrasound Ameliorates Experimental Renal Fibrosis

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Role of ROCK in diabetes-mediated cardiovascular disease: from bench to bedsidePrincipal Investigator

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Construction of medicine for radiation emergency system using iPS cell bank

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Role of ROCK activity in cardiovascular diseases: a translational researchPrincipal Investigator

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[Book] ICU看護実践ハンドブック2013

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[Book] 糖尿病と酸化ストレス2011

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[Journal Article] Combination of Flow-Mediated Vasodilation and Nitroglycerine-Induced Vasodilation Is More Effective for Prediction of Cardiovascular Events.2016

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[Journal Article] Ratio of serum levels of AGEs to soluble form of RAGE is a predictor of endothelial function.2015

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[Journal Article] Exogenous nitric oxide inhibits Rho-associated kinase activity in patients with angina pectoris: a randomized controlled trial.2015

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[Journal Article] Rho-associated kinase activity is an independent predictor of cardiovascular events in acute coronary syndrome.2015

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[Journal Article] Effect of aldosterone-producing adenoma on endothelial function and Rho-associated kinase activity in patients with primary aldosteronism.2015

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NOMA KENSUKE 野間玄督