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Otsubo Yoshitaka  大坪 義孝

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Ohtubo Yoshitaka  大坪 義孝

OHTUBO Yoshitaka  大坪 義孝

OTSUBO Yoshitaka  大坪 義孝

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Researcher Number 00380725
Other IDs
Affiliation (Current) 2025: 九州工業大学, 大学院生命体工学研究科, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2023: 九州工業大学, 大学院生命体工学研究科, 准教授
2015 – 2017: 九州工業大学, 大学院生命体工学研究科, 准教授
2012 – 2013: 九州工業大学, 生命体工学研究科(研究院), 准教授
2011: 九州工業大学, 生命体工学研究科(研究院), 助教
2008 – 2009: Kyushu Institute of Technology, 生命体工学研究科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Cell biology / Neurophysiology and muscle physiology / Biophysics
Keywords
Principal Investigator
パッチクランプ法 / 活動電位 / ヘミチャネル / 味蕾細胞 / 細胞型 / 伝達物質 / シグナル伝達 / G蛋白質連結型受容体 / 脱分極 / 膜電位振動 … More / 色素取込実験 / 振動性膜電位 / A型K電流 / バイオサイチン取込 / 穿孔パッチクランプ / 振動性受容器電位 / 味応答 / 味細胞 / 茸状乳頭味蕾 / 穿孔パッチクランプ法 / G蛋白質連結型味受容体 / マウス味蕾 / 受容器電位 / 振動性脱分極応答 / パッチクランプ / 味蕾構造 / 神経線維 / 遺伝子サブタイプ / 電位依存性Kチャネル / 味神経線維 / 細胞間情報伝達 / 電位依存性Kチャネル / ATP受容体 / アセチルコリン受容体 / 傍分泌 / リアルタイムPCR / 免疫染色 / 免疫染色法 / single cell RT-PCR / 電位依存性チャネル / 味情報伝播 / 電位依存性 / コネキシン / 味覚器 / イオンチャネル / 受容体 Less
  • Research Projects

    (4 results)
  • Research Products

    (41 results)
  • Co-Researchers

    (1 People)
  •  Taste signal transduction in taste receptor cellsPrincipal Investigator

    • Principal Investigator
      Ohtubo Yoshitaka
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
    • Research Institution
      Kyushu Institute of Technology
  •  Structural and functional analysis of cell networks within taste buds.Principal Investigator

    • Principal Investigator
      Ohtubo Yoshitaka
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Kyushu Institute of Technology
  •  Detecting mechanism of tastant concentrations by a kinetic model for action potentials and generator potentials.Principal Investigator

    • Principal Investigator
      OHTUBO Yoshitaka
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Kyushu Institute of Technology
  •  Cell to cell interaction within mouse taste budsPrincipal Investigator

    • Principal Investigator
      OTSUBO Yoshitaka
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biophysics
    • Research Institution
      Kyushu Institute of Technology

All 2024 2023 2022 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008

All Journal Article Presentation

  • [Journal Article] Characteristics of A-type voltage-gated K+ currents expressed on sour-sensing type III taste receptor cells in mice2024

    • Author(s)
      Takeru Moribayashi, Yoshiki Nakao, and Yoshitaka Ohtubo
    • Journal Title

      Cell and Tissue Research

      Volume: - Issue: 3 Pages: 353-369

    • DOI

      10.1007/s00441-024-03887-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06270
  • [Journal Article] Taste receptor cells generate oscillating receptor potentials by activating G protein-coupled taste receptors2022

    • Author(s)
      Yoshiki Nakao, Katsumi Tateno and Yoshitaka Ohtubo
    • Journal Title

      Frontires in Physiology

      Volume: -

    • DOI

      10.3389/fphys.2022.883372

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06270
  • [Journal Article] Selective expression of muscarinic acetylcholine receptor subtype M3 by mouse type III taste bud cells.2016

    • Author(s)
      Mori Y, Eguchi K, Yoshii K, Ohtubo Y
    • Journal Title

      Pflugers Archiv : European journal of physiology.

      Volume: 468(11) Issue: 11-12 Pages: 2053-2059

    • DOI

      10.1007/s00424-016-1879-5

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07053
  • [Journal Article] Cell-type-dependent action potentials and voltage-gated currents in mouse fungiform taste buds.2014

    • Author(s)
      Kimura K, Ohtubo Y, Tateno K, Takeuchi K, Kumazawa T, Yoshii K.
    • Journal Title

      European Journal of Neuroscience

      Volume: 39(1) Issue: 1 Pages: 24-34

    • DOI

      10.1111/ejn.12388

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Journal Article] Cell-type-dependent action potentials and voltage-gated currents in mouse fungiform taste buds2014

    • Author(s)
      Kimura K, Ohtubo Y, Tateno K, Takeuchi K, Kumazawa T, Yoshii K.
    • Journal Title

      European Journal of Neuroscience

      Volume: 39(1) Pages: 24-34

    • Data Source
      KAKENHI-PROJECT-23700469
  • [Journal Article] Subtype-dependent postnatal development of taste receptor cells in mouse fungiform taste buds.2012

    • Author(s)
      Ohtubo Y, Iwamoto M, Yoshii K.
    • Journal Title

      European Journal of Neuroscience

      Volume: 未定 Issue: 11 Pages: 1661-1671

    • DOI

      10.1111/j.1460-9568.2012.08068.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Journal Article] Network model of chemical-sensing system inspired by mouse taste buds.2011

    • Author(s)
      Tateno K, Igarashi J, Ohtubo Y, Nakada K, Miki T, Yoshii K.
    • Journal Title

      Biological Cybernetics

      Volume: 105 (1) Issue: 1 Pages: 21-27

    • DOI

      10.1007/s00422-011-0447-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Journal Article] 哺乳類味蕾細胞の電位依存性Naチャネル2010

    • Author(s)
      大坪義孝
    • Journal Title

      日本味と匂学会誌 17巻1号

      Pages: 21-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770124
  • [Presentation] 甘味刺激によるバイオサイチン取込味細胞数の定量的解析2024

    • Author(s)
      嘉悦勝博, 中尾吉貴, 中川裕之, 大坪義孝
    • Organizer
      第101回 日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-21K06270
  • [Presentation] 味刺激によって放出される神経伝達物質の探索2023

    • Author(s)
      北野沙樹, 髙橋奈々, 大坪義孝, 越村匡博, 山崎隆志
    • Organizer
      第29回日本生物工学会九州支部福岡大会
    • Data Source
      KAKENHI-PROJECT-21K06270
  • [Presentation] 味刺激および高カリウム刺激によるバイオサイチン取込味細胞数の定量的解析2023

    • Author(s)
      嘉悦勝博,髙橋奈々,中尾吉貴, 中川裕之, 大坪義孝
    • Organizer
      第57回 日本味と匂学会大会
    • Data Source
      KAKENHI-PROJECT-21K06270
  • [Presentation] Voltage-gated channels and neurotransmitter receptors in mouse taste bud cells.2017

    • Author(s)
      Ohtubo Y
    • Organizer
      The 51th Annual Meeting of the Japanese Association for the Study of Taste and Smell
    • Data Source
      KAKENHI-PROJECT-15K07053
  • [Presentation] Electrophysiological properties of A-type potassium currents in mouse fungiform taste bud cells2017

    • Author(s)
      Moribayashi T, Ohtubo Y
    • Organizer
      The 51th Annual Meeting of the Japanese Association for the Study of Taste and Smell
    • Data Source
      KAKENHI-PROJECT-15K07053
  • [Presentation] Electrophysiological study on ATP-permeable voltage-gated ion channels in type II cells of mouse taste bud cells.2016

    • Author(s)
      Ohtubo Y, Takashima M
    • Organizer
      10th Federation of European Neuroscience Societies (FENS)
    • Place of Presentation
      Copenhagen, Denmark
    • Year and Date
      2016-07-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07053
  • [Presentation] Numerical studies on the expression of cell-type marker proteins in mouse foliate and circumvallate taste buds.2016

    • Author(s)
      Ogata T, Ohtubo Y
    • Organizer
      17th International Symposium on Olfaction and Taste (ISOT2016)
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2016-06-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07053
  • [Presentation] 葉状乳頭味蕾における細胞型マーカー分子発現細胞の定量的解析2015

    • Author(s)
      緒方貴宏、大坪義孝
    • Organizer
      日本味と匂学会第49回大会
    • Place of Presentation
      じゅうろくプラザ、岐阜市
    • Year and Date
      2015-09-24
    • Data Source
      KAKENHI-PROJECT-15K07053
  • [Presentation] 単一味蕾に発現する biocytin 取り込み細胞数の定量的薬理学的解析2015

    • Author(s)
      岩本正史、大坪義孝
    • Organizer
      日本味と匂学会第49回大会
    • Place of Presentation
      じゅうろくプラザ、岐阜市
    • Year and Date
      2015-09-24
    • Data Source
      KAKENHI-PROJECT-15K07053
  • [Presentation] マウス茸状乳頭味蕾細胞のCs 非感受性外向き電流に対する各種ブロッカーの効果2015

    • Author(s)
      高島麻都花、大坪義孝
    • Organizer
      日本味と匂学会第49回大会
    • Place of Presentation
      じゅうろくプラザ、岐阜市
    • Year and Date
      2015-09-24
    • Data Source
      KAKENHI-PROJECT-15K07053
  • [Presentation] Postnatal development of taste buds in mouse soft palates.2013

    • Author(s)
      Ohtubo Y, Hashiguchi Y, Yamasaki T, Yoshii K.
    • Organizer
      The 47th Annual Meeting of the Japanese Association for the Study of Taste and Smell
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Action potential shapes for a change in TEA-insensitive current ratio in mouse taste bud cell model.2013

    • Author(s)
      Tateno K, Ohtubo Y, Kimura K, Takeuchi K, Kumazawa T, Yoshii K.
    • Organizer
      FENS Featured Regional Meeting
    • Place of Presentation
      Prague, Czech Republic
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Aging of voltage-gated currents in mouse fungiform taste bud cells.2013

    • Author(s)
      Y. Ohtubo, K. Takeuchi, K. Yoshii
    • Organizer
      The Journal of Physiological Sciences, Proceedings of the 90th Annual Meeting
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Postnatal development of taste buds in mouse soft palates2013

    • Author(s)
      Ohtubo Y, Hashiguchi Y, Yamasaki T, Yoshii K.
    • Organizer
      The 47th Annual Meeting of the Japanese Association for the Study of Taste and Smell
    • Place of Presentation
      Sendai, Japan(Program and Abstracts, p 86, P-011)
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Aging effects on electrophysiological properties of taste receptor cells in ~20-month-old mice2013

    • Author(s)
      Takeuchi K, Ohtubo Y, Yoshii K.
    • Organizer
      FENS Featured Regional Meeting
    • Place of Presentation
      Prague, Czech Republic(Final Programme p50, PI-D-106)
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Aging effects on electrophysiological properties of taste receptor cells in ~20-month-old mice.2013

    • Author(s)
      Takeuchi K, Ohtubo Y, Yoshii K.
    • Organizer
      FENS Featured Regional Meeting
    • Place of Presentation
      Prague, Czech Republic
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Aging of voltage-gated currents in mouse fungiform taste bud cells2013

    • Author(s)
      Ohtubo Y, Takeuchi K, Yoshii K.
    • Organizer
      The Journal of Physiological Sciences, Proceedings of the 90th Annual Meeting
    • Place of Presentation
      Tokyo, Japan(Volume 63, supplement 1, p S253, 3PK-079)
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Action potential shapes for a change in TEA-insensitive current ratio in mouse taste bud cell model2013

    • Author(s)
      Tateno K, Ohtubo Y, Kimura K, Takeuchi K, Kumazawa T, Yoshii K.
    • Organizer
      FENS Featured Regional Meeting
    • Place of Presentation
      Prague, Czech Republic(Final Programme p50, PI-D-105)
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Action potentials and voltage-gated currents of mouse taste bud cells.2012

    • Author(s)
      K. Yoshii, K. Kimura, Y. Ohtubo, K. Kumazawa
    • Organizer
      8th FENS Forum of Neuroscience
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Action potentials and voltage-gated currents of mouse taste bud cells2012

    • Author(s)
      Yoshii K, Kimura K, Ohtubo Y, Kumazawa T.
    • Organizer
      8th FENS Forum of Neuroscience
    • Place of Presentation
      Barcelona, Spain(Programme p184)
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Cell type dependence of voltage-gated sodium channel currents in fungiform taste bud cells.2012

    • Author(s)
      Y. Ohtubo, K. Yoshii
    • Organizer
      8th FENS Forum of Neuroscience
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Cell type dependence of voltage-gated sodium channel currents in fungiform taste bud cells2012

    • Author(s)
      Ohtubo Y, Yoshii K.
    • Organizer
      8th FENS Forum of Neuroscience
    • Place of Presentation
      Barcelona, Spain(Programme p184)
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Bullfrog taste nerve responses under hyperosmotic conditions.2012

    • Author(s)
      T. Kumazawa, K. Mashiyama, Y. Ohtubo, K. Yoshii
    • Organizer
      8th FENS Forum of Neuroscience
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Selective expression of a muscarinic acetylcholine receptor M3 on type III cells in mouse fungiform taste buds.2011

    • Author(s)
      Mori Y, Ohtubo Y, Yoshii K.
    • Organizer
      8th International Brain Research Organization (IBRO) World congress of neuroscience
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Postnatal development of taste bud cells in mouse fungiform papillae2011

    • Author(s)
      Ohtubo Y, Iwamoto M, Yoshii K.
    • Organizer
      8th International Brain Research Organization (IBRO) World congress of neuroscience
    • Place of Presentation
      Florence, Italy(Program book p118, C242)
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Postnatal development of taste bud cells in mouse fungiform papillae.2011

    • Author(s)
      Ohtubo Y, Iwamoto M, Yoshii K.
    • Organizer
      8th International Brain Research Organization (IBRO) World congress of neuroscience
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-23700469
  • [Presentation] Voltage-gated sodium currents of cell types in mouse taste bud cells2009

    • Author(s)
      Yoshitaka Ohtubo
    • Organizer
      The 7^<th> ISMNTOP
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-20770124
  • [Presentation] 味蕾細胞電位依存性ナトリウムチャネルの電気生理学的・分子生物学的研究2009

    • Author(s)
      大坪義孝
    • Organizer
      第60回西日本生理学会
    • Place of Presentation
      福岡
    • Year and Date
      2009-11-06
    • Data Source
      KAKENHI-PROJECT-20770124
  • [Presentation] Voltage-gated sodium currents of cell types in mouse taste bud cells2009

    • Author(s)
      Yoshitaka Ohtubo
    • Organizer
      The 7th ISMNTOP
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-20770124
  • [Presentation] 味蕾細胞の電位依存性ナトリウムチャネル2009

    • Author(s)
      大坪義孝
    • Organizer
      第43回味と匂学会
    • Place of Presentation
      北海道旭川市
    • Year and Date
      2009-09-03
    • Data Source
      KAKENHI-PROJECT-20770124
  • [Presentation] 味蕾細胞の電位依存性ナトリウムチャネル2009

    • Author(s)
      大坪義孝
    • Organizer
      第43回大会 日本味と匂学会
    • Place of Presentation
      旭川市
    • Year and Date
      2009-09-03
    • Data Source
      KAKENHI-PROJECT-20770124
  • [Presentation] VOLTAGE-GATED Na^+ CURRENTS OF EACH CELL TYPE IN MOIAE TASTE BUDS2008

    • Author(s)
      Yoshitaka Ohtubo
    • Organizer
      ECRO 2008
    • Place of Presentation
      スロベニアポルトローシユ
    • Data Source
      KAKENHI-PROJECT-20770124
  • [Presentation] Voltage-gated Na+ currents of each cell type in mouse taste buds2008

    • Author(s)
      Yoshitaka Ohtubo
    • Organizer
      ECRO 2008
    • Place of Presentation
      スロベニア
    • Year and Date
      2008-09-03
    • Data Source
      KAKENHI-PROJECT-20770124
  • 1.  山崎 隆志 (20270382)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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