KAJIHARA Atsuhisa 梶原淳久

Researcher Number	00382317
Affiliation (based on the past Project Information) *help	2012 – 2016: 奈良県立医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Surgical dentistry Except Principal Investigator Surgical dentistry
Keywords	Principal Investigator BRCA2 / 相同組み換え修復 / 温熱 / ＤＮＡ二本鎖切断 / ＢＲＣＡ２ / DNA二本鎖切断 / recombination assay / siRNA / 口腔がん細胞 / DNA修復 / 臨床腫瘍学 … More Except Principal Investigator … More 5-FU / 化学療法 / 口腔がん / DNA修復 / oral cancer / BRCA2 / 5-fluorouracil / DNA repair Less

Selection of DSBs repair pathways in heat-induced cell death mediated by BRCA2Principal Investigator
- Principal Investigator
  
  Atsuhisa Kajihara
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nara Medical University
research on the potential molecular targets in DNA repair pathway for enhancing chemosensitivity of oral cancer cells
- Principal Investigator
  
  KIRITA TADAAKI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Nara Medical University
Study of hyperthermic sensitization as a target of DNA repair pathways in the oral cancer cellsPrincipal Investigator
- Principal Investigator
  
  KAJIHARA Atsuhisa
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nara Medical University

All 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] The BRCA2 gene is a potential target during 5-fluorouracil therapy in human oral cancer cells2014
- Author(s)
  Nakagawa Y., Kajihara A., Takahashi A., Kondo N., Mori E.,Kirita T., Ohnishi T
- Journal Title
  
  Oncology reports
  
  Volume: 31 Pages: 2001-2006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659902
[Journal Article] The BRCA2 gene is a potential molecular target during 5-fluorouracil2014
- Author(s)
  Nakagawa Y, Kajihara H, Takahashi A, Kondo N, Mori E, Kirita T, Ohnishi T
- Journal Title
  
  Oncology Reports
  
  Volume: 31 Pages: 2001-2006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659902
[Journal Article] The BRCA2 gene is a potential molecular target during 5-fluorouracil therapy in human oral cancer cells.2014
- Author(s)
  Yousuke Nakagawa, Atsushi Kajihara, Akihisa Takahashi, Natsuko Kondo, Eiichiro Mori, Tadaaki Kirita, Takeo Ohnishi
- Journal Title
  
  Oncol Rep.
  
  Volume: 31 (5) Issue: 5 Pages: 2001-2006
- DOI
  10.3892/or.2014.3080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390303, KAKENHI-PROJECT-24792244, KAKENHI-PROJECT-25514007
[Journal Article] Depression of p53-independent Akt survival signals in human oral cancer cells bearing mutated p53 gene after exposure to high-LET radiation.2012
- Author(s)
  Nakagawa Y., Takahashi A., Kajihara A., Yamakawa N., Imai Y., Ota I., Okamoto N., Mori E., Noda T., Furusawa Y., Kirita T., Ohnishi T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 423 Pages: 654-660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659902
[Journal Article] Depression of p53-independent Akt survival signals in human oral cancer cells bearing mutated p53 gene after exposure to high-LET radiation2012
- Author(s)
  Nakagawa Y., Takahashi A., Kajihara A., Yamakawa N., Imai Y., Ota I., Okamoto N., Mori E., Noda T., Furusawa Y., Kirita T., Ohnishi T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 423(4)(Epub) Pages: 654-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659902
[Journal Article] Depression of p53-independent Akt survival signals in human oral cancer cells bearing mutated p53 gene after exposure to high-LET radiation.2012
- Author(s)
  Yosuke Nakagawa,Akihisa Takahashi,Atsuhisa Kajihara,Nobuhiro Yamakawa,Yuichiro Imai,Ichiro Ota,Noritomo Okamoto,Eiichiro Mori,Taichi Noda,Yoshiya Furusawa,Tadaaki Kirita,Takeo Ohnishi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 423 (4) Issue: 4 Pages: 654-660
- DOI
  10.1016/j.bbrc.2012.06.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659224, KAKENHI-PROJECT-23390303, KAKENHI-PROJECT-23592537, KAKENHI-PROJECT-23659594, KAKENHI-PROJECT-24792244
[Presentation] DNA修復を標的とした温熱増感効果2013
- Author(s)
  梶原淳久、仲川洋介、高橋昭久、桐田忠昭、大西武雄
- Organizer
  日本ハイパーサーミア学会第30回大会
- Place of Presentation
  横浜シンポジア
- Data Source
  KAKENHI-PROJECT-24659902
[Presentation] DNA 修復を標的とした温熱増感効果2013
- Author(s)
  梶原淳久
- Organizer
  日本ハイパーサーミア学会第30回大会
- Place of Presentation
  横浜シンポジア
- Data Source
  KAKENHI-PROJECT-24792244
[Presentation] DNA修復を標的とした温熱増感効果2013
- Author(s)
  梶原淳久
- Organizer
  日本ハイパーサーミア学会第30回大会
- Place of Presentation
  横浜シンポジア
- Data Source
  KAKENHI-PROJECT-24792244
[Presentation] 口腔がんにおける重粒子線照射による生存シグナルを介した細胞周期および細胞死の制御2012
- Author(s)
  仲川洋介、梶原淳久、山川延宏、桐田忠昭
- Organizer
  第57回日本口腔外科学会総会・学術大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24659902
[Presentation] 口腔癌細胞に対する DNA 修復を標的とした温熱増感効果についての検討2012
- Author(s)
  梶原淳久
- Organizer
  第57回日本口腔外科学会総会・学術大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24792244
[Presentation] 口腔癌細胞に対する相同組換え修復を標的とした温熱増感効果についての検討2012
- Author(s)
  梶原淳久
- Organizer
  第66回日本口腔科学会学術集会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-24792244
[Presentation] Enhancement of heat sensitivity by depression of DSB repair2012
- Author(s)
  Kajihara A
- Organizer
  ICHO & JCTM 2012
- Place of Presentation
  kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24792244
[Presentation] 口腔癌細胞に対するDNA修復を標的とした温熱増感効果についての検討2012
- Author(s)
  梶原淳久
- Organizer
  第57回日本口腔外科学会総会・学術大会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-24792244
[Presentation] 口腔癌細胞に対する相同組換え修復を標的とした温熱増感効果についての検討2012
- Author(s)
  梶原淳久
- Organizer
  第66回NPO法人日本口腔科学会学術集会
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-24792244
[Presentation] 口腔癌細胞に対する相同組換え修復を標的とした温熱増感効果についての検討2012
- Author(s)
  梶原淳久、仲川洋介、桐田忠昭
- Organizer
  第66回NPO法人日本口腔科学会学術集会
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-24659902
[Presentation] Enhancement of heat sensitivity by depression of DSB repair2012
- Author(s)
  Atsuhisa Kajihara
- Organizer
  ICHO&JCTM2012
- Place of Presentation
  Hyatt Regency Kyoto
- Data Source
  KAKENHI-PROJECT-24792244
[Presentation] Enhancement of heat sensitivity by depression of homologous recombination repair
- Author(s)
  Atsuhisa Kajihara
- Organizer
  第31回日本ハイパーサーミア学会学術大会、第6回ACHO同時開催
- Place of Presentation
  AOSSA（福井県福井市）
- Year and Date
  2014-09-05 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-26463052
[Presentation] 口腔癌細胞に対して相同組み換え修復を標的にすると温熱感受性が増強する
- Author(s)
  梶原淳久
- Organizer
  第59回日本口腔外科学会総会・学術大会
- Place of Presentation
  幕張メッセ（千葉県千葉市）
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-26463052

1. KIRITA TADAAKI (70201465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. 高橋昭久 (60275336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

KAJIHARA Atsuhisa 梶原 淳久

Research Projects

Research Products

Co-Researchers

Selection of DSBs repair pathways in heat-induced cell death mediated by BRCA2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

research on the potential molecular targets in DNA repair pathway for enhancing chemosensitivity of oral cancer cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of hyperthermic sensitization as a target of DNA repair pathways in the oral cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The BRCA2 gene is a potential target during 5-fluorouracil therapy in human oral cancer cells2014

Author(s)

Journal Title

Data Source

[Journal Article] The BRCA2 gene is a potential molecular target during 5-fluorouracil2014

Author(s)

Journal Title

Data Source

[Journal Article] The BRCA2 gene is a potential molecular target during 5-fluorouracil therapy in human oral cancer cells.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Depression of p53-independent Akt survival signals in human oral cancer cells bearing mutated p53 gene after exposure to high-LET radiation.2012

Author(s)

Journal Title

Data Source

[Journal Article] Depression of p53-independent Akt survival signals in human oral cancer cells bearing mutated p53 gene after exposure to high-LET radiation2012

Author(s)

Journal Title

Data Source

[Journal Article] Depression of p53-independent Akt survival signals in human oral cancer cells bearing mutated p53 gene after exposure to high-LET radiation.2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] DNA修復を標的とした温熱増感効果2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] DNA 修復を標的とした温熱増感効果2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] DNA修復を標的とした温熱増感効果2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 口腔がんにおける重粒子線照射による生存シグナルを介した細胞周期および細胞死の制御2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 口腔癌細胞に対する DNA 修復を標的とした温熱増感効果についての検討2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 口腔癌細胞に対する相同組換え修復を標的とした温熱増感効果についての検討2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Enhancement of heat sensitivity by depression of DSB repair2012

Author(s)

KAJIHARA Atsuhisa 梶原淳久