TAKAHASHI Yuji 高橋祐司

Researcher Number	00392499
Affiliation (based on the past Project Information) *help	2013: 独立行政法人国立成育医療研究センター, その他部局等, 研究員 2012: 独立行政法人国立成育医療研究センター, 生殖・細胞医療研究部, 研究員 2008: National Research Institute for Child Health and Development, 周産期診療部・不妊診療科, 研究員 2008: National Research Institute for Child Health and Development, 周産期診療部不妊診療科, 研究員 2008: 国立成育医療センター(研究所), 生殖・細胞医療研究部, 共同研究員 … More 2007: National Research Institute for Child Health and Development, 国立成育医療センター・周産期診療部不妊診療科, 研究員 2007: 国立成育医療センター(研究所), 生殖医療研究部, 共同研究員 2006: 国立成育医療センター(研究所), 周産期診療部不妊診療科, 研究員 Less
Review Section/Research Field	Principal Investigator Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator 胚発生メカニズム / 着床不全モデル / 生殖補助医療 / 発生・分化 / プロテアーゼ / 胚盤胞 / 浸潤 / 着床 / 生殖医学 Except Principal Investigator テトラスバニン … More / テトラスパニン / チューブリン / エキソソーム / CD9 / 膜融合 / 受精 / 生殖医学 Less

ヒト生命萌芽の分子機構の解明～生殖補助医療の向上及び安全性を目指して～Principal Investigator
- Principal Investigator
  
  高橋祐司
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  National Research Institute for Child Health and Development
Functional analysis of fusogenic factors related to infertility and its clinical application
- Principal Investigator
  
  MIYADO Kenji
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  National Research Institute for Child Health and Development
Regulation of embryonic invasion by novel metalloprotease ADAMTS family genesPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Yuji
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  National Research Institute for Child Health and Development

All 2010 2009 2008 2007 2006

All Journal Article Presentation Book

[Book] 生殖における酸化ストレスの生理的役割と不妊症疾患(実験医学26)2008
- Author(s)
  高橋祐司、宮戸健二、齋藤英和
- Data Source
  KAKENHI-PROJECT-19390431
[Journal Article] Age-associated changes in the subcellular localization of phosphorylated p38 MAPK in human granulosa cells.2010
- Author(s)
  Ito M, Miyado K, Nakagawa K, Muraki M, Imai M, Yamakawa N, Qin J, Hosoi Y, Saito H, Takahashi Y.
- Journal Title
  
  Mol Hum Reprod. 16(12)
  
  Pages: 928-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390431
[Journal Article] Age-associated changes in the subcellular localization of phosphorylated p38 MAPK in human granulosa cells.2010
- Author(s)
  Ito M, Miyado K, Nakagawa K, Muraki M, Imai M, Yamakawa N, Qin J, Hosoi Y, Saito H, Takahashi Y.
- Journal Title
  
  Mol Hum Reprod.
  
  Volume: 16 Pages: 928-937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390431
[Journal Article] Shortening of human cell life span by induction of p16ink4a through the platelet-derived growth factor receptor beta.2009
- Author(s)
  Takahashi H, Toyoda M, Birumachi J, Horie A, Uyama T, Miyado K, Matsumoto K, Saito H, Umezawa A.
- Journal Title
  
  J Cell Physiol 221(2)
  
  Pages: 335-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390431
[Journal Article] The frequency of ovulation from the affected ovary decreases following laparoscopic cystectomy in infertile women with unilateral endometrioma during a natural cycle2008
- Author(s)
  Horikawa T, Nakagawa K, Ohgi S, Kojima R, Takahashi Y, et al
- Journal Title
  
  J Assist Reprod Genet 25
  
  Pages: 239-244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] Glutathione S-transferase theta1 expressed in granulosa cells as a biomarker for oocyte quality in age-related infertility.2008
- Author(s)
  Ito M, Muraki M, Takahashi Y, Imai M, Tsukui T, Yamakawa N, Nakagawa K, Ohgi S, Horikawa T, Iwasaki W, Iida A, Nishi Y, Yanase T, Nawata H, Miyado K, Kono T, Hosoi Y, Saito H
- Journal Title
  
  Fertility and Sterility 90
  
  Pages: 1026-1035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] Glutathione S-transferase thetal expressed in granulosa cells as a biomarker for oocyte quality in age-related infertility2008
- Author(s)
  Ito M, Muraki M, Takahashi Y, et al
- Journal Title
  
  Fertil Steril 90
  
  Pages: 1026-1035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice2008
- Author(s)
  Miyado K, Yoshida K, Yamagata K, Takahashi Y, et al
- Journal Title
  
  Proc Natl Acad Sci, USA 105
  
  Pages: 12921-12926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice.2008
- Author(s)
  Miyado K, Yoshida K, Yamagata K, Sakakibara K, Okabe M, Wang X, Miyamoto K, Akutsu H, Kondo T, Takahashi Y, Ban T, Ito C, Toshimori K, Nakamura A, Ito M, Miyado M, Mekada E, Umezawa A.
- Journal Title
  
  Proc Natl Acad Sci USA(Miyado K is a corresponding author; Faculty of 1000 Biology推薦論文) 105(35)
  
  Pages: 12921-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390431
[Journal Article] 女性の加齢に伴う生殖の異常2008
- Author(s)
  齊藤英和、中川浩次、高橋祐司
- Journal Title
  
  日本医師会雑誌 137
  
  Pages: 35-38
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] 生殖における酸化ストレスの生理的役割と不妊症疾患2008
- Author(s)
  高橋祐司、宮戸健二、齊藤英和
- Journal Title
  
  実験医学 26
  
  Pages: 586-590
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice2008
- Author(s)
  Miyado K, Yoshida K, Yamagata K, Sakakibara K, Okabe M, Wang X, Miyamoto K, Akutsu H, Kondo T, Takahashi Y, Ban T, Ito C, Toshimori K, Nakamura A, Ito M, Miyado M, Mekada E, Umezawa A
- Journal Title
  
  Proc Natl Acad Sci USA 105
  
  Pages: 12921-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390431
[Journal Article] The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice2008
- Author(s)
  Miyado K, Yoshida K, Yamagata K, Sakakibara K, Okabe M, Wang X, Miyamoto K, Akutsu H, Kondo T, Takahashi Y, Ban T, Ito C, Toshimori K, Nakamura A, Ito M, Miyado M, Mekada E, Umezawa A.
- Journal Title
  
  Proc Natl Acad Sci USA 105(35)
  
  Pages: 12921-6
- Data Source
  KAKENHI-PROJECT-19390431
[Journal Article] Glutathione S-transferase theta 1 expressed in granulosa cells as a biomarker for oocyte quality in age-related infertility2008
- Author(s)
  Ito M, Muraki M, Takahashi Y, Imai M, Tsukui T, Yamakawa N, Nakagawa K, Ohgi S, Horikawa T, Iwasaki W, Iida A, Nishi Y, Yanase T, Nawata H, Miyado K, Kono T, Hosoi Y, Saito H.
- Journal Title
  
  Fertil Steril 90(4)
  
  Pages: 1026-35
- Data Source
  KAKENHI-PROJECT-19390431
[Journal Article] 女性の加齢に伴う生殖の異常2008
- Author(s)
  齊藤英和、中川浩次、高橋祐司
- Journal Title
  
  日本医師会雑誌 137
  
  Pages: 35-38
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] Spontaneous transformation of human granulosa cell tumours into an aggressive phenotype : a metastasis model cell line2008
- Author(s)
  Imai M, Muraki M, Takamatsu K, Saito H, Seiki M, Takahashi Y
- Journal Title
  
  BMC Cancer 8
  
  Pages: 319-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice.2008
- Author(s)
  Miyado K, Yoshida K, Yamagata K, Sakakibara K, Okabe M, Wang X, Miyamoto K, Akutsu H, Kondo T, Takahashi Y, Ban T, Ito C, Toahimori K, Nakamura A, Ito M, Miyado M, Mekada E, Umezawa A,
- Journal Title
  
  Proceedings of the National Academy of Sciences, USA 105
  
  Pages: 12921-12926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] 生殖における酸化ストレスの生理的役割と不妊症疾患2008
- Author(s)
  高橋祐司、宮戸健二、齊藤英和
- Journal Title
  
  実験医学 26
  
  Pages: 586-590
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] Glutathione S-transferase theta 1 expressed in granulosa cells as a biomarker for oocyte quality in age-related infertility.2008
- Author(s)
  Ito M, Muraki M, Takahashi Y, Imai M, Tsukui T, Yamakawa N, Nakagawa K, Ohgi S, Horikawa T, Iwasaki W, Iida A, Nishi Y, Yanase T, Nawata H, Miyado K, Kono T, Hosoi Y, Saito H.
- Journal Title
  
  Fertil Steril 90(4)
  
  Pages: 1026-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390431
[Journal Article] The frequency of ovulation from the affected ovary decreases following laparoscopic cystectomy in infertile women with unilateral endometrioma during a natural cycle.2008
- Author(s)
  Horikawa T, Nakagawa K, Ohgi S, Kojima R, Nakashima A, Ito M, Takahashi Y, Saito H
- Journal Title
  
  Journal of Assisted Reproduction and Genetics 25
  
  Pages: 239-244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] Spontaneous transformation of human granulosa cell tumours into an aggressive phenotype : a metastasis model cell line.2008
- Author(s)
  Imai M, Muraki M, Takamatsu K, Saito H, Seiki M, Takahashi Y
- Journal Title
  
  BMC Cancer 8
  
  Pages: 319-319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] Hyaline cartilage formation and enchondral ossification modeled with KUM5 and OP9 chondroblasts.2007
- Author(s)
  Sugiki T, Uyama T, Toyoda M, Morioka H, Kume S, Miyado K, Matsumoto K, Saito H, Tsumaki N, Takahashi Y, Toyama Y, Umezawa A.
- Journal Title
  
  J Cell Biochem 100(5)
  
  Pages: 1240-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390431
[Journal Article] Glutathione S-transferase thetal e)rpressed in granulosa cells as a biomarker for oocyte quality in age-related infertility2007
- Author(s)
  Ito M, Muraki M, Takahashi Y, Imai M, et. al.
- Journal Title
  
  Ferti Steril (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] 生殖医療における女性のエイジング2006
- Author(s)
  齊藤英和、中川浩次、高橋祐司
- Journal Title
  
  臨床婦人科産科 60
  
  Pages: 1341-1345
- Data Source
  KAKENHI-PROJECT-18591818
[Journal Article] GnRHアゴニストの臨床応用-体外受精2006
- Author(s)
  齊藤英和、中川浩次、児島梨絵子、高橋祐司
- Journal Title
  
  日本臨床 64
  
  Pages: 80-84
- Data Source
  KAKENHI-PROJECT-18591818
[Presentation] ヒト顆粒膜細胞におけるp38MAPKの加齢変化2008
- Author(s)
  伊藤めぐむ、宮戸健二、齊藤英和、高橋祐司
- Organizer
  第61回日本酸化ストレス学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18591818
[Presentation] 新規卵巣老化マーカーとしての抗アポトーシス分子Bag-12008
- Author(s)
  高橋祐司, 村木美帆, 伊藤めぐむ, 今井美沙, 齊藤英和
- Organizer
  日本酸化ストレス学会
- Place of Presentation
  京都
- Year and Date
  2008-06-20
- Data Source
  KAKENHI-PROJECT-18591818
[Presentation] 新規卵巣老化マーカーとしての抗アポトーシス分子Bag-12008
- Author(s)
  高橋祐司、村木美帆、伊藤めぐむ、今井美沙、齊藤英和
- Organizer
  第61回日本酸化ストレス学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18591818
[Presentation] Autophagic control of the development of murine oocytes2007
- Author(s)
  Takahashi Y, Saito H
- Organizer
  The 47th annual meeting of American Society for Cell Biology
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-18591818
[Presentation] GSTT1 as an aging marker in granulosa cells2007
- Author(s)
  Muraki M, Kono T, Saito H, Takahashi Y
- Organizer
  The 47th annual meeting of American Society for Cell Biology
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-18591818
[Presentation] GSTT1 as al aging marker in granulosa cells2007
- Author(s)
  Muraki M, Kono T, Saito H, Takahashi Y
- Organizer
  American Society for Cell Biology
- Place of Presentation
  ワシントンDC
- Year and Date
  2007-12-02
- Data Source
  KAKENHI-PROJECT-18591818
[Presentation] Spontaneous transformation of human granulosa cell tumor into aggressive phenotype2007
- Author(s)
  Imai M, Seiki M, Saito H, Takahashi Y
- Organizer
  The 47th annual meeting of American Society for Cell Biology
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-18591818
[Presentation] Autophagic control of the development of muhle oocytes2007
- Author(s)
  Takahashi Y, Saito H
- Organizer
  Amehcan Society for Cell Biology
- Place of Presentation
  ワシントンDC
- Year and Date
  2007-12-04
- Data Source
  KAKENHI-PROJECT-18591818
[Presentation] Spontaneous transformation of human granulosa cell tumor into aggressive phenotype2007
- Author(s)
  Imai M, Seiki M, Saito H, Takahashi Y
- Organizer
  Americal Society for Cell Biology
- Place of Presentation
  ワシントンDC
- Year and Date
  2007-12-02
- Data Source
  KAKENHI-PROJECT-18591818

1. SAITO Hidekazu (90125766)

# of Collaborated Projects: 2 results

# of Collaborated Products: 26 results
2. MIYADO Kenji (60324844)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
3. AKUTSU Hidenori (50347225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 宮本潔子 (20415590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 宮戸真美 (00386252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
6. 梅澤明弘 (70213486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKAHASHI Yuji 高橋 祐司

Research Projects

Research Products

Co-Researchers

ヒト生命萌芽の分子機構の解明～生殖補助医療の向上及び安全性を目指して～Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of fusogenic factors related to infertility and its clinical application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of embryonic invasion by novel metalloprotease ADAMTS family genesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 生殖における酸化ストレスの生理的役割と不妊症疾患(実験医学26)2008

Author(s)

Data Source

[Journal Article] Age-associated changes in the subcellular localization of phosphorylated p38 MAPK in human granulosa cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] Age-associated changes in the subcellular localization of phosphorylated p38 MAPK in human granulosa cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] Shortening of human cell life span by induction of p16ink4a through the platelet-derived growth factor receptor beta.2009

Author(s)

Journal Title

Data Source

[Journal Article] The frequency of ovulation from the affected ovary decreases following laparoscopic cystectomy in infertile women with unilateral endometrioma during a natural cycle2008

Author(s)

Journal Title

Data Source

[Journal Article] Glutathione S-transferase theta1 expressed in granulosa cells as a biomarker for oocyte quality in age-related infertility.2008

Author(s)

Journal Title

Data Source

[Journal Article] Glutathione S-transferase thetal expressed in granulosa cells as a biomarker for oocyte quality in age-related infertility2008

Author(s)

Journal Title

Data Source

[Journal Article] The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice2008

Author(s)

Journal Title

Data Source

[Journal Article] The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice.2008

Author(s)

Journal Title

Data Source

[Journal Article] 女性の加齢に伴う生殖の異常2008

Author(s)

Journal Title

Data Source

[Journal Article] 生殖における酸化ストレスの生理的役割と不妊症疾患2008

Author(s)

Journal Title

Data Source

[Journal Article] The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice2008

Author(s)

Journal Title

Data Source

[Journal Article] The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice2008

Author(s)

Journal Title

Data Source

[Journal Article] Glutathione S-transferase theta 1 expressed in granulosa cells as a biomarker for oocyte quality in age-related infertility2008

Author(s)

Journal Title

Data Source

[Journal Article] 女性の加齢に伴う生殖の異常2008

Author(s)

Journal Title

TAKAHASHI Yuji 高橋祐司