Kuwabara Takashige 桑原孝成

… Alternative Names

KUWABARA Takashige 桑原孝成

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Researcher Number	00393356
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(医), 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 熊本大学, 大学院生命科学研究部(医), 准教授 2017 – 2019: 熊本大学, 大学院生命科学研究部(医), 講師 2017: 熊本大学, 医学部, 助教 2016: 熊本大学, 大学院生命科学研究部(医), 助教 2016: 熊本大学, 大学院生命科学研究部, 助教 … More 2014 – 2015: 熊本大学, 生命科学研究部, 助教 2014: 熊本大学, 生命科学研究部腎臓内科学, 助教 2013: 京都大学, 医学(系)研究科(研究院), 院内助教 2012: 京都大学, 大学院・医学研究科, 医員 2011 – 2012: 京都大学, 医学(系)研究科(研究院), 医員 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related Except Principal Investigator Basic Section 59010:Rehabilitation science-related / Kidney internal medicine / Rehabilitation science/Welfare engineering
Keywords	Principal Investigator MRP8 / 自然炎症 / マクロファージ / 急性腎障害 / 糸球体腎炎 / 細胞間クロストーク / 糖尿病性腎症 / 細胞性免疫 / 虚血再灌流 / ワクチン … More / 接着因子 / 腎炎 / Mincle / GBM腎炎 / ペプチドワクチン / 生命予後 / 透析患者 / 抗GBM腎炎 / 内因性リガンド / 糸球体障害 / 糸球体内クロストーク / 半月体形成性腎炎 / 慢性炎症 / レニン・アンジオテンシン系 / 脂質代謝異常 / TLR4 … More Except Principal Investigator TRPV4 / 慢性腎臓病 / 急性腎障害 / CKD / 炎症 / プレコンディショニング / 全身温熱刺激 / 温熱 / シスプラチン / HSP27 / リハビリテーション / 温熱療法 / マクロファージ / 全身温熱 / 温熱性血管拡張 / 腎皮質血流量 / 交感神経活動 / 血管内皮細胞 / 腎微小循環調節 / 予後 / M2マクロファージ / M1マクロファージ / heat shock protein / 尿細管 / thermal preconditioning / cisplatin / tubular injury / MYLK発現減少 / ROCK1発現減少 / 温熱感受性遺伝子群 / 細胞内シグナル伝達 / TRPV3,4チャネル / 疫学研究（前向きコホート） / 温熱習慣（入浴、サウナ） / ウェブアンケートシステム / ライフスタイルプロフィール / 疫学研究 / 生活習慣 / 温熱習慣 / 内部障害リハビリテーション / シスプラチン腎症 / Hsp27 / TRPV4 channel / シスプラチン誘発性腎症 / TRPV4チャネル / 熱ショックタンパク質 / Double Product / 腎局所循環 / Hsp / 温熱プレコンディショニング / アポトーシス減少 / 近位尿細管障害 / 低温サウナ / 慢性腎臓病モデルマウス / 内部障害のリハビリテーション / 腎不全 / 非薬物療法 / 全身温熱の反復 / 酸化ストレス抑制 / アポトーシス抑制 / 尿細管障害軽減 / 機能維持 / 反復効果 / 内科 / AKI / renin-angiotensin system / 肥満症 / metabolic syndrome / アルドステロン / 高血圧 / 自然炎症 / N型カルシウムチャネル / ナトリウム利尿ペプチド / レニン・アンジオテンシン系 / 糖尿病性腎症 / メタボリック症候群 / 内分泌学 / 腎臓学 Less

Role of MRP8 in the mechanism of acute kidney injury through cell-mediated immunityPrincipal Investigator
- Principal Investigator
  
  桑原孝成
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kumamoto University
Elucidation of the role of TRPV4 channel in the effect of repetitive hyperthermia on the progression of chronic kidney disease
- Principal Investigator
  
  飯山準一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kumamoto Health Science University
Role of renally expressed TRP channels in thermal preconditioning
- Principal Investigator
  
  Iwashita Yoshihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kumamoto Health Science University
Role of MRP8 in the progression of glomerulonephritisPrincipal Investigator
- Principal Investigator
  
  Kuwabara Takashige
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kumamoto University
Elucidation of the mechanism of cisplatin-induced nephropathy reduction by thermal preconditioning
- Principal Investigator
  
  Iwashita Yoshihiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kumamoto Health Science University
The effects of systemic thermal habits on chronic kidney disease onset and progression and their underlying mechanisms elucidation
- Principal Investigator
  
  iiyama junichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kumamoto Health Science University
Elucidation of the role of homeostatic inflammation in the AKI to CKD transition mechanism focusing on the time phase changes
- Principal Investigator
  
  Hayata Manabu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University
The role of MRP8 as a therapeutic target in chronic kidney diseasePrincipal Investigator
- Principal Investigator
  
  Kuwabara Takashige
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University
Suppressive effects of mild sauna stimulation on chronic kidney disease progression
- Principal Investigator
  
  iiyama junichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Kumamoto Health Science University
Roles of humoral factors and organ-organ or cell-cell communications in the development and progression of metabolic kidney diseases
- Principal Investigator
  
  MUKOYAMA Masashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University
The relationship between homeostatic inflammation and renin-angiotensin system in the progression of diabetic nephropathyPrincipal Investigator
- Principal Investigator
  
  KUWABARA Takashige
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University
  Kyoto University
Novel mechanism of progression of diabetic nephropathy by hyperlipidemia: MRP8/TLR4 signalingPrincipal Investigator
- Principal Investigator
  
  KUWABARA Takashige
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyoto University

[Book] 今日の治療指針　2024年版2024
- Author(s)
  桒原孝成
- Total Pages
  3
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22K08357
[Book] 腎臓内科レジデントマニュアル2023
- Author(s)
  桒原孝成
- Total Pages
  9
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-22K08357
[Book] 腎疾患研究の最新の話題2017
- Author(s)
  桒原孝成、向山政志
- Total Pages
  2
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-15K09268
[Book] 特集　腎と老化「老化と体液量調節機構」2016
- Author(s)
  桒原孝成、向山政志
- Total Pages
  4
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-15K09268
[Book] 肥満関連腎臓病2016
- Author(s)
  桒原孝成、向山政志
- Total Pages
  5
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-15K09268
[Book] 主治医として診る高血圧診療「BNP, NT-proBNP」2016
- Author(s)
  桒原孝成、向山政志
- Total Pages
  5
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-15K09268
[Book] S100タンパク質ファミリーMyeloid-related protein 8（MRP8）2014
- Author(s)
  桒原孝成、向山政志
- Total Pages
  5
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-25860673
[Book] 糖尿病性腎症における自然炎症の意義とその分子機序2013
- Author(s)
  桑原孝成
- Total Pages
  7
- Publisher
  フジメディカル出版
- Data Source
  KAKENHI-PROJECT-23790939
[Book] ナトリウム利尿ペプチド2012
- Author(s)
  桑原孝成
- Total Pages
  7
- Publisher
  ライフメディコム
- Data Source
  KAKENHI-PROJECT-23790939
[Book] Annual Review 腎臓2012
- Author(s)
  桑原孝成、向山政志、中尾一和.
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23790939
[Journal Article] Characterization of gene expression in the kidney of renal tubular cell-specific NFAT5 knockout mice2024
- Author(s)
  Ono Makoto、Izumi Yuichiro、Maruyama Kosuke、Yasuoka Yukiko、Hiramatsu Akiko、Aramburu Jose、L?pez-Rodr?guez Cristina、Nonoguchi Hiroshi、Kakizoe Yutaka、Adachi Masataka、Kuwabara Takashige、Mukoyama Masashi
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 326 Issue: 3 Pages: F394-F410
- DOI
  10.1152/ajprenal.00233.2023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18291, KAKENHI-PROJECT-22K08357, KAKENHI-PROJECT-23K07676, KAKENHI-PROJECT-21K08280
[Journal Article] Suppression of Indoxyl Sulfate Accumulation Reduces Renal Fibrosis in Sulfotransferase 1a1-Deficient Mice2023
- Author(s)
  Hou Huixian、Horikawa Mai、Narita Yuki、Jono Hirofumi、Kakizoe Yutaka、Izumi Yuichiro、Kuwabara Takashige、Mukoyama Masashi、Saito Hideyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 14 Pages: 11329-11329
- DOI
  10.3390/ijms241411329
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18291, KAKENHI-PROJECT-22K08357, KAKENHI-PROJECT-23K06281, KAKENHI-PROJECT-23K07676, KAKENHI-PROJECT-21K08280, KAKENHI-PROJECT-23K24047
[Journal Article] Increased numbers of pre-operative circulating monocytes predict risk of developing cardiac surgery-associated acute kidney injury in conditions requiring cardio pulmonary bypass.2023
- Author(s)
  Okadome Y, Morinaga J, Yamanouchi Y, Matsunaga E, Fukami H, Kadomatsu T, Horiguchi H, Sato M, Sugizaki T, Hayata M, Sakaguchi T, Hirayama R, Ishimura T, Kuwabara T, Usuku K, Yamamoto T,Mukoyama M, Suzuki R, Fukui T, and Oike Y
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 27 Issue: 4 Pages: 329-339
- DOI
  10.1007/s10157-022-02313-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K08357, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-22K16429, KAKENHI-PROJECT-21K16061, KAKENHI-PROJECT-21K20935, KAKENHI-PROJECT-23K18291
[Journal Article] Pre-dialysis blood pressure and cardiovascular mortality in Japan: need for much stricter control?2023
- Author(s)
  Mukoyama Masashi、Kuwabara Takashige
- Journal Title
  
  Hypertension Research
  
  Volume: 47 Issue: 3 Pages: 811-812
- DOI
  10.1038/s41440-023-01523-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08357
[Journal Article] Need to continue or discontinue RAS inhibitors as CKD stage advances? Any alternative?2023
- Author(s)
  Fujimoto Daisuke、Kuwabara Takashige、Mukoyama Masashi
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 8 Pages: 2048-2050
- DOI
  10.1038/s41440-023-01318-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08357, KAKENHI-PROJECT-22K16223
[Journal Article] Chapter 1: Evaluation of kidney function in patients undergoing anticancer drug therapy, from clinical practice guidelines for the management of kidney injury during anticancer drug therapy 2022.2023
- Author(s)
  Muto S, Matsubara T, Inoue T, Kitamura H, Yamamoto K, Ishii T, Yazawa M, Yamamoto R, Okada N, Mori K, Yamada H, Kuwabara T, Yonezawa A, Fujimaru T, Kawano H, Yokoi H, Doi K, Hoshino J, Yanagita M.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 28 Issue: 10 Pages: 1259-1297
- DOI
  10.1007/s10147-023-02372-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08350, KAKENHI-PROJECT-22K08357
[Journal Article] A Serine Protease Inhibitor, Camostat Mesilate, Suppresses Urinary Plasmin Activity and Alleviates Hypertension and Podocyte Injury in Dahl Salt-Sensitive Rats2023
- Author(s)
  Iwata Yasunobu、Deng Qinyuan、Kakizoe Yutaka、Nakagawa Terumasa、Miyasato Yoshikazu、Nakagawa Miyuki、Nishiguchi Kayo、Nagayoshi Yu、Narita Yuki、Izumi Yuichiro、Kuwabara Takashige、Adachi Masataka、Mukoyama Masashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 21 Pages: 15743-15743
- DOI
  10.3390/ijms242115743
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18291, KAKENHI-PROJECT-22K08357, KAKENHI-PROJECT-23K07676, KAKENHI-PROJECT-21K08280
[Journal Article] Chapter 3: Management of kidney injury caused by cancer drug therapy, from clinical practice guidelines for the management of kidney injury during anticancer drug therapy 20222023
- Author(s)
  Ando Yuichi、Nishiyama Hiroyuki、Shimodaira Hideki、et al.
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 28 Issue: 10 Pages: 1315-1332
- DOI
  10.1007/s10147-023-02382-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07248, KAKENHI-PROJECT-22K08350, KAKENHI-PROJECT-22K08357, KAKENHI-PROJECT-18K09270, KAKENHI-PROJECT-20H03575
[Journal Article] The serine protease plasmin plays detrimental roles in epithelial sodium channel activation and podocyte injury in Dahl salt-sensitive rats2022
- Author(s)
  Deng Qinyuan、Kakizoe Yutaka、Iwata Yasunobu、Nakagawa Terumasa、Miyasato Yoshikazu、Nakagawa Miyuki、Nishiguchi Kayo、Nagayoshi Yu、Adachi Masataka、Narita Yuki、Izumi Yuichiro、Kuwabara Takashige、Tsuda Yuko、Mukoyama Masashi
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 1 Pages: 50-62
- DOI
  10.1038/s41440-022-01064-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08280, KAKENHI-PROJECT-22K08357, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-20K16047
[Journal Article] A case of chyluria with nephrotic-range proteinuria caused by lymphatic malformation, leading to a diagnosis of Klippel-Trenaunay syndrome2022
- Author(s)
  Izumi Yuichiro、Date Ryosuke、Mizumoto Teruhiko、Nakagawa Terumasa、Kakizoe Yutaka、Adachi Masataka、Kuwabara Takashige、Mukoyama Masashi
- Journal Title
  
  CEN Case Reports
  
  Volume: 12 Issue: 2 Pages: 205-209
- DOI
  10.1007/s13730-022-00747-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08280, KAKENHI-PROJECT-22K08357
[Journal Article] Role of renin-angiotensin system blockade in advanced CKD: to use or not to use?2022
- Author(s)
  Mukoyama Masashi、Kuwabara Takashige
- Journal Title
  
  Hypertension Research
  
  Volume: - Issue: 6 Pages: 1072-1075
- DOI
  10.1038/s41440-022-00902-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-22K08357
[Journal Article] A Novel VCP modulator KUS121 exerts renoprotective effects in ischemia-reperfusion injury with retaining ATP and restoring ERAD-processing capacity.2022
- Author(s)
  Hata Yusuke、Date Ryosuke、Fujimoto Daisuke、Ikeda Hanako Ohashi、Umemoto Shuro、Kanki Tomoko、Nishiguchi Yoshihiko、Mizumoto Teruhiko、Hayata Manabu、Kakizoe Yutaka、Izumi Yuichiro、Kakizuka Akira、Mukoyama Masashi、Kuwabara Takashige
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: - Issue: 5 Pages: F577-F586
- DOI
  10.1152/ajprenal.00392.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-21K08280, KAKENHI-PROJECT-22K08311, KAKENHI-PROJECT-22K08357, KAKENHI-PROJECT-22K16223, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-19H03435
[Journal Article] Camostat mesilate, a serine protease inhibitor, exerts aquaretic effects and decreases urinary exosomal AQP2 levels2022
- Author(s)
  Kakizoe Yutaka、Nakagawa Terumasa、Iwata Yasunobu、Deng Qinyuan、Adachi Masataka、Miyasato Yoshikazu、Nakagawa Miyuki、Nagayoshi Yu、Nishiguchi Kayo、Narita Yuki、Izumi Yuichiro、Kuwabara Takashige、Tomita Kimio、Kitamura Kenichiro、Mukoyama Masashi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 150 Issue: 4 Pages: 204-210
- DOI
  10.1016/j.jphs.2022.09.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08280, KAKENHI-PROJECT-22K08357, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-20K08638, KAKENHI-PROJECT-20K16047
[Journal Article] Osteocrin ameliorates adriamycin nephropathy via p38 mitogen-activated protein kinase inhibition2021
- Author(s)
  Handa Takaya、Mori Keita P.、Ishii Akira、Ohno Shoko、Kanai Yugo、Watanabe-Takano Haruko、Yasoda Akihiro、Kuwabara Takashige、Takahashi Nobuyuki、Mochizuki Naoki、Mukoyama Masashi、Yanagita Motoko、Yokoi Hideki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 21835-21835
- DOI
  10.1038/s41598-021-01095-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-20K17278, KAKENHI-PROJECT-20H03697, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-20K08633, KAKENHI-PROJECT-20K08877, KAKENHI-PROJECT-21K08269, KAKENHI-PROJECT-21K16189
[Journal Article] A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats2021
- Author(s)
  Mizumoto Teruhiko、Kakizoe Yutaka、Nakagawa Terumasa、Iwata Yasunobu、Miyasato Yoshikazu、Uchimura Kohei、Adachi Masataka、Deng Qinyuan、Hayata Manabu、Morinaga Jun、Miyoshi Taku、Izumi Yuichiro、Kuwabara Takashige、Sakai Yoshiki、Tomita Kimio、Kitamura Kenichiro、Mukoyama Masashi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 146 Issue: 4 Pages: 192-199
- DOI
  10.1016/j.jphs.2021.04.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-19K08729, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-21K08280
[Journal Article] Vaccine targeting ANGPTL3 ameliorates dyslipidemia and associated diseases in mouse models of obese dyslipidemia and familial hypercholesterolemia2021
- Author(s)
  Fukami Hirotaka、Morinaga Jun、Nakagami Hironori、Hayashi Hiroki、Okadome Yusuke、Matsunaga Eiji、Kadomatsu Tsuyoshi、Horiguchi Haruki、Sato Michio、Sugizaki Taichi、Kuwabara Takashige、Miyata Keishi、Mukoyama Masashi、Morishita Ryuichi、Oike Yuichi
- Journal Title
  
  Cell Reports Medicine
  
  Volume: 2 Issue: 11 Pages: 100446-100446
- DOI
  10.1016/j.xcrm.2021.100446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-20K17288, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-21K15508, KAKENHI-PROJECT-21K16061, KAKENHI-PROJECT-21K20935
[Journal Article] Hyperglycemia and Thrombocytopenia　― Combinatorially Increase the Risk of Mortality in Patients With Acute Myocardial Infarction Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation ―2021
- Author(s)
  Okadome Yusuke、Morinaga Jun、Fukami Hirotaka、Hori Kota、Ito Teruhiko、Sato Michio、Miyata Keishi、Kuwabara Takashige、Mukoyama Masashi、Suzuki Ryusuke、Tsunoda Ryusuke、Oike Yuichi
- Journal Title
  
  Circulation Reports
  
  Volume: 3 Issue: 12 Pages: 707-715
- DOI
  10.1253/circrep.CR-21-0043
- NAID
  130008128243
- ISSN
  2434-0790
- Year and Date
  2021-12-10
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-20K17288, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-21K16061, KAKENHI-PROJECT-21K20935
[Journal Article] Mineralocorticoid receptor blockers for moderate kidney dysfunction: more merit than ever?2021
- Author(s)
  Mukoyama Masashi、Kuwabara Takashige、Adachi Masataka
- Journal Title
  
  Hypertension Research
  
  Volume: 44 Issue: 10 Pages: 1352-1354
- DOI
  10.1038/s41440-021-00690-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08728
[Journal Article] Salt-Sensitive Hypertension of the Renal Tubular Cell-Specific NFAT5 (Nuclear Factor of Activated T-Cells 5) Knockout Mice2021
- Author(s)
  Hiramatsu Akiko、Izumi Yuichiro、Eguchi Koji、Matsuo Naomi、Deng Qinyuan、Inoue Hideki、Nakayama Yushi、Nonoguchi Hiroshi、Aramburu Jose、Lopez-Rodriguez Cristina、Kakizoe Yutaka、Adachi Masataka、Kuwabara Takashige、Kim-Mitsuyama Shokei、Mukoyama Masashi
- Journal Title
  
  Hypertension
  
  Volume: 78 Issue: 5 Pages: 1335-1346
- DOI
  10.1161/hypertensionaha.121.17435
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-21K08280
[Journal Article] Osteocrin, a bone-derived humoral factor, exerts a renoprotective role in ischemia-reperfusion injury in mice2021
- Author(s)
  Nishiguchi Yoshihiko、Hata Yusuke、Date Ryosuke、Fujimoto Daisuke、Umemoto Shuro、Kanki Tomoko、Yokoi Hideki、Mori Keita P、Handa Takaya、Watanabe-Takano Haruko、Kanai Yugo、Yasoda Akihiro、Izumi Yuichiro、Kakizoe Yutaka、Mochizuki Naoki、Mukoyama Masashi、Kuwabara Takashige
- Journal Title
  
  Nephrology Dialysis Transplantation
  
  Volume: 37 Issue: 3 Pages: 444-453
- DOI
  10.1093/ndt/gfab286
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-20K08633, KAKENHI-PROJECT-20K08877, KAKENHI-PROJECT-21K08280, KAKENHI-PROJECT-22K08357
[Journal Article] Regulation of Rhcg, an ammonia transporter, by aldosterone in the kidney.2021
- Author(s)
  Eguchi K, Izumi Y, Yasuoka Y, Nakagawa T, Ono M, Maruyama K, Matsuo N, Hiramatsu A, Inoue H, Nakayama Y, Nonoguchi H, Lee HW, Weiner ID, Kakizoe Y, Kuwabara T, Mukoyama M.
- Journal Title
  
  J Endocrinol.
  
  Volume: in press Issue: 2 Pages: 95-112
- DOI
  10.1530/joe-20-0267
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-18K08247, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-21K08280
[Journal Article] Circulating angiopoietin-like protein 2 levels and arterial stiffness in patients receiving maintenance hemodialysis: A cross-sectional study.2020
- Author(s)
  Fukami H, Morinaga J, Okadome Y, Nishiguchi Y, Iwata Y, Kanki T, Nakagawa T, Izumi Y, Kakizoe Y, Kuwabara T, Horiguchi H, Sato M, Kadomatsu T, Miyata K, Tajiri T, Oike Y, Mukoyama M.
- Journal Title
  
  Atherosclerosis.
  
  Volume: 315 Pages: 18-23
- DOI
  10.1016/j.atherosclerosis.2020.10.890
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-20K17288, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-18K08247, KAKENHI-PROJECT-19K17607
[Journal Article] The predictive role of serum calprotectin on mortality in hemodialysis patients with high phosphoremia2020
- Author(s)
  Kanki Tomoko、Kuwabara Takashige、Morinaga Jun、Fukami Hirotaka、Umemoto Shuro、Fujimoto Daisuke、Mizumoto Teruhiko、Hayata Manabu、Kakizoe Yutaka、Izumi Yuichiro、Tajiri Saeko、Tajiri Tetsuya、Kitamura Kenichiro、Mukoyama Masashi
- Journal Title
  
  BMC Nephrology
  
  Volume: 21 Issue: 1 Pages: 158-158
- DOI
  10.1186/s12882-020-01812-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-19K08729, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-18K08247
[Journal Article] Suppressed ER-associated degradation by intraglomerular cross talk between mesangial cells and podocytes causes podocyte injury in diabetic kidney disease.2020
- Author(s)
  Fujimoto D, Kuwabara T, Hata Y, Umemoto S, Kanki T, Nishiguchi Y, Mizumoto T, Hayata M, Kakizoe Y, Izumi Y, Takahashi S, Mukoyama M.
- Journal Title
  
  FASEB J
  
  Volume: 34 Issue: 11 Pages: 854-860
- DOI
  10.1096/fj.202000078rr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-19K08729, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-18K08247
[Journal Article] Ablation of Myeloid Cell MRP8 Ameliorates Nephrotoxic Serum-induced Glomerulonephritis by Affecting Macrophage Characterization through Intraglomerular Crosstalk2020
- Author(s)
  Hata Yusuke、Kuwabara Takashige、Mori Kiyoshi、Kan Youngna、Sato Yuki、Umemoto Shuro、Fujimoto Daisuke、Kanki Tomoko、Nishiguchi Yoshihiko、Yokoi Hideki、Kakizoe Yutaka、Izumi Yuichiro、Yanagita Motoko、Mukoyama Masashi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 3056-3056
- DOI
  10.1038/s41598-020-59970-9
- NAID
  120006956435
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-17K09697, KAKENHI-PROJECT-17K09704, KAKENHI-PROJECT-17K09705, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-17K16081, KAKENHI-PROJECT-19K08682, KAKENHI-PROJECT-20K08633, KAKENHI-PROJECT-18K08247
[Journal Article] Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study2019
- Author(s)
  Morinaga J, Kakuma T, Fukami H, Hayata M, Uchimura K, Mizumoto T, Kakizoe Y, Miyoshi T, Shiraishi N, Adachi M, Izumi Y, Kuwabara T, Okadome Y, Sato M, Horiguchi H, Sugizaki T, Kadomatsu T, Miyata K, Tajiri S, Tajiri T, Tomita K, Kitamura K, Oike Y, Mukoyama M.
- Journal Title
  
  Nephrology Dialysis Transplantation
  
  Volume: 印刷中 Issue: 5 Pages: 854-860
- DOI
  10.1093/ndt/gfz236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08247, KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-19K17607, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-17K09704, KAKENHI-PROJECT-17K09705, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-19K08729, KAKENHI-PROJECT-20K08611
[Journal Article] Insufficiency of urinary acid excretion of overweight or obese patients with chronic kidney disease and its involvement with renal tubular injury.2019
- Author(s)
  Eguchi K, Izumi Y, Nakayama Y, Inoue H, Marume T, Matsuo N, Hiramatsu A, Ono M, Kakizoe Y, Kuwabara T, Nonoguchi H, Mukoyama M.
- Journal Title
  
  Nephrology
  
  Volume: 24 Issue: 11 Pages: 1131-1141
- DOI
  10.1111/nep.13553
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-17K09702, KAKENHI-PROJECT-18K08247, KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-16K09654, KAKENHI-PROJECT-17K09705
[Journal Article] Regression of hepatitis C virus‐associated membranoproliferative glomerulonephritis with direct‐acting antiviral therapy after liver transplantation2019
- Author(s)
  Okamura Keiko、Kuwabara Takashige、Enoki Hiroko、Kohda Yukimasa、Adachi Masataka、Hayashida Shintaro、Inomata Yukihiro、Mukoyama Masashi
- Journal Title
  
  Nephrology
  
  Volume: 24 Issue: 11 Pages: 1198-1199
- DOI
  10.1111/nep.13492
- Data Source
  KAKENHI-PROJECT-19K08728
[Journal Article] Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response2018
- Author(s)
  Miyasato Yoshikazu、Yoshizawa Tatsuya、Sato Yoshifumi、Nakagawa Terumasa、Miyasato Yuko、Kakizoe Yutaka、Kuwabara Takashige、Adachi Masataka、Ianni Alessandro、Braun Thomas、Komohara Yoshihiro、Mukoyama Masashi、Yamagata Kazuya
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 5927-5927
- DOI
  10.1038/s41598-018-24257-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-26461234, KAKENHI-PROJECT-17K09705, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-16K09758, KAKENHI-PROJECT-16H06276
[Journal Article] Increase of Total Nephron Albumin Filtration and Reabsorption in Diabetic Nephropathy.2017
- Author(s)
  Mori KP, Yokoi H, Kasahara M, Imamaki H, Ishii A, Kuwabara T, Koga K, Kato Y, Toda N, Ohno S, Kuwahara K, Endo T, Nakao K, Yanagita M, Mukoyama M, Mori K.
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: 28 Issue: 1 Pages: 278-289
- DOI
  10.1681/asn.2015101168
- NAID
  120005820888
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293187, KAKENHI-PROJECT-26461224, KAKENHI-PROJECT-26461225, KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-16K15442, KAKENHI-PROJECT-16K15469, KAKENHI-PROJECT-17K16080, KAKENHI-PROJECT-17H04174
[Journal Article] TSS-Seq analysis of low pH-induced gene expression in intercalated cells of the renal collecting duct2017
- Author(s)
  Izumi Y
- Journal Title
  
  PLos One
  
  Volume: 12 Issue: 8 Pages: e0184185-e0184185
- DOI
  10.1371/journal.pone.0184185
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09654, KAKENHI-PROJECT-16K08505, KAKENHI-PROJECT-17K09702, KAKENHI-PROJECT-17K09705, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-26461234, KAKENHI-PROJECT-16K19493
[Journal Article] A protease-activated receptor-1 antagonist protects against podocyte injury in a mouse model of nephropathy2017
- Author(s)
  Guan Yu、Nakano Daisuke、Zhang Yifan、Li Lei、Liu Wenhua、Nishida Motohiro、Kuwabara Takashige、Morishita Asahiro、Hitomi Hirofumi、Mori Kiyoshi、Mukoyama Masashi、Masaki Tsutomu、Hirano Katsuya、Nishiyama Akira
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 135 Issue: 2 Pages: 81-88
- DOI
  10.1016/j.jphs.2017.09.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-16K09518, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15K09266, KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-16H05092
[Journal Article] Obesity-promoting and anti-thermogenic effects of neutrophil gelatinase-associated lipocalin in mice2017
- Author(s)
  Ishii Akira、Katsuura Goro、Imamaki Hirotaka、Kimura Hiroyuki、Mori Keita P.、Kuwabara Takashige、Kasahara Masato、Yokoi Hideki、Ohinata Kousaku、Kawanishi Tomoko、Tsuchida Junichi、Nakamoto Yuji、Nakao Kazuwa、Yanagita Motoko、Mukoyama Masashi、Mori Kiyoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 15501-15501
- DOI
  10.1038/s41598-017-15825-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09697, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-17K16079, KAKENHI-PROJECT-17H01566, KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-16K15469
[Journal Article] Crucial role of mesangial cell-derived connective tissue growth factor in a mouse model of anti-glomerular basement membrane glomerulonephritis.2017
- Author(s)
  Toda N, Mori K, Kasahara M, Ishii A, Koga K, Ohno S, Mori KP. Kato Y, Osaki K, Kuwabara T, Kojima K, Taura D, Sone M, Matsusaka T, Nakao K, Mukoyama M, Yanagita M, Yokoi H.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 42114-42114
- DOI
  10.1038/srep42114
- NAID
  120005997757
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461225, KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-17K09697, KAKENHI-PROJECT-17K16079, KAKENHI-PROJECT-17K16080, KAKENHI-PROJECT-26461380, KAKENHI-PROJECT-17H01566, KAKENHI-PROJECT-16K15469
[Journal Article] Natriuretic peptide receptor guanylyl cyclase-A pathway counteracts glomerular injury evoked by aldosterone through p38 mitogen-activated protein kinase inhibition.2017
- Author(s)
  Y. Kato, K. Mori, M. Kasahara, K. Osaki, A. Ishii, K.P. Mori, N. Toda, S. Ohno, T. Kuwabara, T. Tokudome, I. Kishimoto, M.A. Saleem, T. Matsusaka, K. Nakao, M. Mukoyama, M. Yanagita, H. Yokoi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 46624-46624
- DOI
  10.1038/srep46624
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-17K09697, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-17K09897, KAKENHI-PROJECT-17K16079, KAKENHI-PROJECT-17K16080, KAKENHI-PROJECT-17H01566, KAKENHI-PROJECT-16K15469
[Journal Article] Mild systemic thermal therapy ameliorates renal dysfunction in a rodent model of chronic kidney disease.2016
- Author(s)
  Iwashita Y, Kuwabara T, Hayata M, Kakizoe Y, Izumi Y, Iiyama J, Kitamura K, Mukoyama M.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: in press Issue: 11 Pages: 1-1
- DOI
  10.1152/ajprenal.00519.2015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-26461234, KAKENHI-PROJECT-15K19459, KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-15K01406, KAKENHI-PROJECT-16K19493
[Journal Article] Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure.2016
- Author(s)
  Ohno S, Yokoi H, Mori K, Kasahara M, Kuwahara K, Fujikura J, Naito M, Kuwabara T, Imamaki H, Ishii A, Saleem MA, Numata T, Mori Y, Nakao K, Yanagita M, Mukoyama M
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 27192-27192
- DOI
  10.1038/srep27192
- NAID
  120007100128
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293187, KAKENHI-PROJECT-26461225, KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-16K15495, KAKENHI-PROJECT-15K08197, KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-26461330, KAKENHI-PROJECT-16K15442, KAKENHI-PROJECT-16K15469
[Journal Article] Transthyretin-related familial amyloidotic polyneuropathy found with abnormal urinalysis at a general health checkup.2016
- Author(s)
  Yoshimura Y, Kuwabara T, Shiraishi N, Kakizoe Y, Tasaki M, Obayashi K, Ando Y, Mukoyama M.
- Journal Title
  
  Nephrology
  
  Volume: 21 Issue: 4 Pages: 341-2
- DOI
  10.1111/nep.12610
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-26461234, KAKENHI-PROJECT-26860372, KAKENHI-PROJECT-15H04841, KAKENHI-PROJECT-15K15195
[Journal Article] An AKI biomarker lipocalin 2 in the blood derives from the kidney in renal injury but from neutrophils in normal and infected conditions.2015
- Author(s)
  Kanda J, Mori K, Kawabata H, Kuwabara T, Mori KP, Imamaki H, Kasahara M, Yokoi H, Mizumoto C, Thoennissen NH, Koeffler HP, Barasch J, Takaori-Kondo A, Mukoyama M, Nakao K.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 19 Issue: 1 Pages: 99-106
- DOI
  10.1007/s10157-014-0952-7
- NAID
  120005678175
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860673, KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-26670458, KAKENHI-PROJECT-15K09268
[Journal Article] Low Serum Neutrophil Gelatinase-associated Lipocalin Level as a Marker of Malnutrition in Maintenance Hemodialysis Patients.2015
- Author(s)
  Imamaki H, Ishii A, Yokoi H, Kasahara M, Kuwabara T, Mori KP, Kato Y, Kuwahara T, Satoh M, Nakatani K, Saito Y, Tomosugi N, Sugawara A, Nakao K, Mukoyama M, Yanagita M, Mori K.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 7 Pages: 99-106
- DOI
  10.1371/journal.pone.0132539
- NAID
  120005678176
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-26461224, KAKENHI-PROJECT-26461225, KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-25461226
[Journal Article] Reduction of Tubular Flow Rate as a Mechanism of Oliguria in the Early Phase of Endotoxemia Revealed by Intravital Imaging.2015
- Author(s)
  Nakano D, Doi K, Kitamura H, Kuwabara T, Mori K, Mukoyama M, Nishiyama A.
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860673
[Journal Article] Reduction of Tubular Flow Rate as a Mechanism of Oliguria in the Early Phase of Endotoxemia Revealed by Intravital Imaging.2015
- Author(s)
  Nakano D, Doi K, Kitamura H, Kuwabara T, Mori K, Mukoyama M, Nishiyama A.
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 26 Issue: 12 Pages: 3035-44
- DOI
  10.1681/asn.2014060577
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-26461226
[Journal Article] MicroRNA-26a inhibits TGF-β-induced extracellular matrix expression in podocytes by targeting CTGF and is downregulated in diabetic nephropathy.2015
- Author(s)
  Koga K, Yokoi H, Mori K, Kasahara K, Kuwabara T, Imamaki H, Ishii A, Mori KP, Kato Y, Ohno S, Toda N, Saleem MA, Sugawara A, Nakao K, Yanagita M, Mukoyama M.
- Journal Title
  
  Diabetologia
  
  Volume: 58 Issue: 9 Pages: 2169-80
- DOI
  10.1007/s00125-015-3642-4
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-26461225, KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-25461246, KAKENHI-PROJECT-26293202, KAKENHI-PROJECT-15K15329
[Journal Article] Do statins play a role in renoprotection?2014
- Author(s)
  Kasahara M, Nakagawa T, Yokoi H, Kuwabara T, Yasuno S, Mori K, Mukoyama M
- Journal Title
  
  Ueshima K. Clin Exp Nephrol
  
  Volume: 18 Issue: 2 Pages: 282-285
- DOI
  10.1007/s10157-013-0928-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591190, KAKENHI-PROJECT-23591191, KAKENHI-PROJECT-25860673
[Journal Article] An AKI biomarker lipocalin 2 in the blood derives from the kidney in renal injury but from neutrophils in normal and infected conditions.2014
- Author(s)
  Kanda J, Mori K, Kawabata H, Kuwabara T, Mori KP, Imamaki H, Kasahara M, Yokoi H, Mizumoto C, Thoennissen NH, Koeffler HP, Barasch J, Takaori-Kondo A, Mukoyama M, Nakao K.
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: in press
- NAID
  120005678175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860673
[Journal Article] Predictive significance of kidney myeloid-related protein 8 expression in patients with obesity- or type 2 diabetes-associated kidney diseases2014
- Author(s)
  Kuwabara T, Mori K, Kasahara M, Yokoi H, Imamaki H, Ishii A, Koga K, Sugawara A, Yasuno S, Ueshima K, Morikawa T, Konishi Y, Imanishi M, Nishiyama A, Nakao K, Mukoyama M
- Journal Title
  
  PloS One
  
  Volume: 9 Issue: 2 Pages: e88942-e88942
- DOI
  10.1371/journal.pone.0088942
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390225, KAKENHI-PROJECT-23591190, KAKENHI-PROJECT-23591191, KAKENHI-PROJECT-25460749, KAKENHI-PROJECT-25461246, KAKENHI-PROJECT-25860673, KAKENHI-PROJECT-26461225
[Journal Article] Do　statins play a role for renoprotection ?2014
- Author(s)
  Kasahara M, Nakagawa T, Yokoi H, Kuwabara T, Yasuno S, Mori K, Mukoyama M, Ueshima K.
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860673
[Journal Article] Macrophage-mediated glucolipotoxicity via MRP8/TLR4 signaling in diabetic nephropathy.2014
- Author(s)
  Kuwabara T, Mori K, Mukoyama M, Kasahara M, Yokoi H, Nakao K.
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860673
[Journal Article] Macrophage-mediated glucolipotoxicity via myeloid-related protein 8/toll-like receptor 4 signaling in diabetic nephropathy2014
- Author(s)
  Kuwabara, T., Mori, K., Mukoyama, M., Kasahara, M., Yokoi, H., Nakao, K.
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: impress Issue: 4 Pages: 584-592
- DOI
  10.1007/s10157-013-0922-5
- NAID
  120005474441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229013, KAKENHI-PROJECT-23591191, KAKENHI-PROJECT-25860673, KAKENHI-PROJECT-26461226, KAKENHI-PROJECT-26670458
[Journal Article] Adrenomedullin-RAMP2 system suppresses ER stress-induced tubule cell death and is involved in kidney protection2013
- Author(s)
  Uetake R, Tanaka M, et al.
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 2 Pages: e87667-e87667
- DOI
  10.1371/journal.pone.0087667
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J07817, KAKENHI-PROJECT-23390225, KAKENHI-PROJECT-23591191, KAKENHI-PROJECT-25460330, KAKENHI-PROJECT-25860673, KAKENHI-PROJECT-25893225, KAKENHI-PROJECT-26293183
[Journal Article] Peritoneal fibrosis and high transport are induced in mildly pre-injured peritoneum by 3,4-dideoxyglucosone-3-ene in mice2013
- Author(s)
  Yokoi, H., Kasahara, M., Mori, K., Kuwabara, T., Toda, N., Yamada, R., Namoto, S., Yamamoto, T., Seki, N., Souma, N., Yamaguchi, T., Sugawara, A., Mukoyama, M., Nakao, K.
- Journal Title
  
  Peritoneal Dialysis International
  
  Volume: 33(2) Issue: 2 Pages: 143-154
- DOI
  10.3747/pdi.2011.00033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229013, KAKENHI-PROJECT-22590910, KAKENHI-PROJECT-23390225, KAKENHI-PROJECT-23591190, KAKENHI-PROJECT-23591191, KAKENHI-PROJECT-23790939
[Journal Article] Exacerbation of diabetic nephropathy by hyperlipidaemia is mediated by toll-like receptor 4 in mice2012
- Author(s)
  T Kuwabara, K Mori, M Mukoyama, et al.
- Journal Title
  
  Diabetologia
  
  Volume: in press
- NAID
  120004225542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790939
[Journal Article] Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis2012
- Author(s)
  Yokoi H, Nakao K, et al
- Journal Title
  
  Kidney Int.
  
  Volume: 81 Issue: 2 Pages: 160-169
- DOI
  10.1038/ki.2011.305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229013, KAKENHI-PROJECT-22590910, KAKENHI-PROJECT-23390225, KAKENHI-PROJECT-23591190, KAKENHI-PROJECT-23591191, KAKENHI-PROJECT-23790939
[Journal Article] 糖尿病性腎症と脂質代謝異常2012
- Author(s)
  桑原孝成、向山政志、中尾一和
- Journal Title
  
  Annual Review腎臓2012
  
  Volume: 1 Pages: 133-139
- Data Source
  KAKENHI-PROJECT-23790939
[Journal Article] Natriuretic peptide receptor guanylyl cyclase-A protects podocytes from aldosterone-induced glomerular injury2012
- Author(s)
  Ogawa Y, Mukoyama M, Yokoi H, Kasahara M, Mori K, Kato Y, Kuwabara T, Imamaki H, Kawanishi T, Koga K, Ishii A, Tokudome T, Kishimoto I, Sugawara A, Nakao K
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 23:1198-1209 Issue: 7 Pages: 1198-1209
- DOI
  10.1681/asn.2011100985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590910, KAKENHI-PROJECT-22790891, KAKENHI-PROJECT-23390225, KAKENHI-PROJECT-23591190, KAKENHI-PROJECT-23591191, KAKENHI-PROJECT-23790939, KAKENHI-PROJECT-24390204, KAKENHI-PUBLICLY-23122525
[Journal Article] Natriuretic peptide receptor guanylyl cyclase-A protects podocytes from aldosterone-induced glomerular injury.2012
- Author(s)
  Y Ogawa, M Mukoyama, T Kuwabara, et al.
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790939
[Journal Article] Exacerbation of diabetic nephropathy by hyperlipidaemia is mediated by Toll-like receptor 4 in mice2012
- Author(s)
  Kuwabara T, Mori K, Mukoyama M, Kasahara M, Yokoi H, Saito Y, Ogawa Y, Imamaki H, Kawanishi T, Ishii A, Koga K, Mori KP, Kato Y, Sugawara A, Nakao K
- Journal Title
  
  Diabetologia
  
  Volume: 55:2256-2266 Issue: 8 Pages: 2256-2266
- DOI
  10.1007/s00125-012-2578-1
- NAID
  120004225542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590910, KAKENHI-PROJECT-23390225, KAKENHI-PROJECT-23591190, KAKENHI-PROJECT-23591191, KAKENHI-PROJECT-23790939
[Journal Article] Exacerbation of diabetic nephropathy by hyperlipidaemia is mediated by toll-like receptor 4 in mice2012
- Author(s)
  Takashige Kuwabara
- Journal Title
  
  Diabetologia
  
  Volume: 55 Pages: 2256-2266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790939
[Patent] 腎保護用の組成物2020
- Inventor(s)
  桒原孝成、池田華子、垣塚彰
- Industrial Property Rights Holder
  桒原孝成、池田華子、垣塚彰
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-194628
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K08728
[Patent] 腎疾患の診断方法2014
- Inventor(s)
  桒原　孝成
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-261973
- Filing Date
  2014-12-25
- Data Source
  KAKENHI-PROJECT-25860673
[Presentation] 熱受容体TRPV4を介した温熱プレコンディショニングによるシスプラチン尿細管細胞傷害の軽減2024
- Author(s)
  前田曙、桒原孝成、岩下佳弘、山田しょう子、飯山準一、向山政志
- Organizer
  第14回腎臓リハビリテーション学会
- Data Source
  KAKENHI-PROJECT-21K11186
[Presentation] VCP ATPaseモジュレーターのERADを介した腎保護効果2023
- Author(s)
  桒原孝成
- Organizer
  第53回日本腎臓学会西部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08357
[Presentation] 二次研究中間報告：J-RBRを用いた抗がん剤による腎障害の腎生検レジストリー研究 (SUBARU-J研究)2023
- Author(s)
  桒原孝成
- Organizer
  第66回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08357
[Presentation] DKDにおける糸球体細胞間の連関2023
- Author(s)
  桒原孝成
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08357
[Presentation] 糖尿病性腎症における糸球体細胞間クロストークの役割2023
- Author(s)
  桒原孝成
- Organizer
  第38回日本糖尿病合併症学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08357
[Presentation] 温和な全身温熱刺激によるシスプラチン腎症軽減効果に果たす TRPV4 の役割2022
- Author(s)
  前田曙、桒原孝成、岩下佳弘、杉本和樹、山田しょう子、飯山準一、向山政志
- Organizer
  第12回日本腎臓リハビリテーション学会学術集会
- Data Source
  KAKENHI-PROJECT-22K11304
[Presentation] 温熱プレコンディショニングによるシスプラチン腎症の軽減効果および熱受容に対するTRPV4の役割2022
- Author(s)
  前田曙，桒原孝成，岩下佳弘，杉本和樹，山田しょう子，飯山準一，向山政志
- Organizer
  第87回日本温泉気候物理医学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K11304
[Presentation] 時間空間的ネットワークで考えるDKDの基礎研究「DKDにおける糸球体細胞間の連関」2022
- Author(s)
  桒原孝成
- Organizer
  第52回日本腎臓学会西部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08357
[Presentation] 腎臓病療養指導士に知ってもらいたい最新情報「イントロダクション2022
- Author(s)
  桒原孝成
- Organizer
  第52回日本腎臓学会西部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08357
[Presentation] 新たなサポーター支援に向けた取り組み「新たなるステージへ向けたサポーター制度」2022
- Author(s)
  桒原孝成
- Organizer
  第65回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08357
[Presentation] 温熱プレコンディショニングによるシスプラチン腎症の軽減効果および熱受容に対するTRPV4の役割2022
- Author(s)
  前田曙、桑原孝成、岩下佳弘、杉本和樹、山田しょう子、飯山準一、向山政志
- Organizer
  第87回日本温泉気候物理医学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K11186
[Presentation] 心腎連関における治療戦略のパラダイムシフト～CKD患者におけるCVDの抑制～「ARNIによる高血圧/CKD診療の新展開」2022
- Author(s)
  桒原孝成
- Organizer
  第65回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08357
[Presentation] Renal complications of immune checkpoint inhibitors」2021
- Author(s)
  Takashige Kuwabara
- Organizer
  10th CKD Frontier
- Invited
- Data Source
  KAKENHI-PROJECT-19K08728
[Presentation] 糖尿病性腎臓病における自然炎症と細胞連関2020
- Author(s)
  桒原孝成、向山政志
- Organizer
  第93回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08728
[Presentation] 骨由来分泌因子Osteocrinが腎障害進展に果たす役割の検討2020
- Author(s)
  西口佳彦、桒原孝成、藤本大介、神吉智子、秦雄介、森慶太、横井秀基、泉裕一郎、柿添豊、望月直樹、向山政志
- Organizer
  第56回高血圧関連疾患モデル学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08728
[Presentation] 生物学的癌治療と腎障害：免疫チェックポイント阻害薬を中心に2020
- Author(s)
  桒原孝成、向山政志
- Organizer
  第50回日本腎臓学会西部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08728
[Presentation] Suppressed ER-associated degradation by intraglomerular crosstalk between podocytes and mesangial cells causes podocyte injury in diabetic kidney disease2020
- Author(s)
  藤本大介、桒原孝成、秦雄介、西口佳彦、柿添豊、泉裕一郎、向山政志
- Organizer
  第24回日本心血管内分泌代謝学会学術総会/24th CVEM
- Data Source
  KAKENHI-PROJECT-19K08728
[Presentation] 地域におけるCKD対策への取組みと腎臓病療養指導士の役割「イントロダクション」2020
- Author(s)
  桒原孝成、向山政志
- Organizer
  第50回日本腎臓学会西部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08728
[Presentation] Intraglomerular crosstalk between mesangial cells and podocytes inhibits normal ER-associated degradation processes and induces podocyte injury in diabetes.2019
- Author(s)
  Daisuke Fujimoto, Takashige Kuwabara, Yusuke Hata, Shuro Umemoto, Tomoko Kanki, Yoshihiko Nishiguchi, Teruhiko Mizumoto, Manabu Hayata, Yuichiro Izumi, Yutaka Kakizoe, Masashi Mukoyama
- Organizer
  Annual Meeting of the American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08728
[Presentation] Involvement of TRPV4 in mild systemic thermal stimulation against cisplatin-induced renal damage2019
- Author(s)
  Maeda A., Iwashita Y., Kuwabara T., Wataru K., Nakamura T., Yamada S., Iiyama J., Mukoyama M.
- Organizer
  World Confederation for Physical Therapy (WCPT)2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K10699
[Presentation] POTENTIAL ROLE OF MRP8 IN GLOMERULAR INJURY THROUGH INTRAGLOMERULAR CROSSTALK AFFECTING MACROPHAGE CHARACTERIZATION2019
- Author(s)
  Yusuke Hata1, Takashige Kuwabara1, Kiyoshi Mori2, Shuro Umemoto1, Tomoko Kanki1, Daisuke Fujimoto1, Yoshihiko Nishiguchi1, Hideki Yokoi3, Masashi Mukoyama1
- Organizer
  World Congress of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08728
[Presentation] The predictive role of serum MRP8/14 (S100A8/A9) on mortality in hemodialysis patients2019
- Author(s)
  Tomoko Kanki, Takashige Kuwabara, Jun Morinaga, Hirotaka Fukami, Shuro Umemoto, Daisuke Fujimoto, Teruhiko Mizumoto, Manabu Hayata, Yutaka Kakizoe, Yuichiro Izumi, Masashi Mukoyama
- Organizer
  Annual Meeting of the American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08728
[Presentation] A Case of Ischemic Enteritis Complicated with Chylous Ascites After the Administration of Azelnidipine in a Patient Undergoing Peritoneal Dialysis.2019
- Author(s)
  Takashige Kuwabara, Makoto Ono, Yu Korogi, Akira Oda, Hideki Inoue, Masashi Mukoyama
- Organizer
  ISPD2019 in Nagoya
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08728
[Presentation] ABLATION OF MRP8 IN MYELOID CELLS AMELIORATES GLOMERULONEPHRITIS BY AFFECTING MACROPHAGE CHARACTERIZATION2019
- Author(s)
  Yusuke Hata1, Takashige Kuwabara1, Kiyoshi Mori2, Shuro Umemoto1, Tomoko Kanki1, Daisuke Fujimoto1, Yoshihiko Nishiguchi1, Yutaka kakizoe1, Yuichiro Izumi1, Hideki Yokoi2, Masashi Mukoyama1
- Organizer
  Annual Meeting of the American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08728
[Presentation] Intraglomerular crosstalk between mesangial cells and podocytes inhibits normal ER-associated degradation processes and induces podocyte injury in diabetic kidney disease.2019
- Author(s)
  Daisuke Fujimoto, Takashige Kuwabara, Yusuke Hata, Shuro Umemoto, Tomoko Kanki, Yoshihiko Nishiguchi, Teruhiko Mizumoto, Manabu Hayata, Yuichiro Izumi, Yutaka Kakizoe, Masashi Mukoyama
- Organizer
  World Congress of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08728
[Presentation] Involvement of TRPV4 in mild systemic thermal stimulation against cisplatin-induced renal damage2019
- Author(s)
  Maeda A. Iwashita Y., Kuwabara T. , Wataru K., Nakamura T . Yamada S., Iiyama J., Mukoyama M.
- Organizer
  World Confederation for Physical Therapy Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03137
[Presentation] 全身温熱刺激が腎組織遺伝子発現に与える影響の網羅的解析2018
- Author(s)
  岩下佳弘、桒原孝成、前田曙、山川依瑞美、中村智明、渡孝輔、山田しょう子、飯山準一、向山政志
- Organizer
  第54回高血圧関連疾患モデル（SHR）学会
- Data Source
  KAKENHI-PROJECT-18H03137
[Presentation] CKDにおけるMRP8の化学修飾の探索とその意義の検討2018
- Author(s)
  神吉智子, 桑原孝成, 梅本周朗, 藤本大介, 水本輝彦, 早田学, 中山憲司, 宮崎有, 井上貴博, 小川修, 向山政志
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-17K09704
[Presentation] シスプラチン誘発性腎障害に対する温和な全身温熱刺激の基礎的研究2018
- Author(s)
  前田曙、岩下佳弘、飯山準一、桒原孝成、向山政志
- Organizer
  第54回高血圧関連疾患モデル（SHR）学会
- Data Source
  KAKENHI-PROJECT-18H03137
[Presentation] 糸球体内クロストークにおけるメサンギウム細胞由来因子によるポドサイトERストレス応答の検討2018
- Author(s)
  藤本大介, 桑原孝成, 梅本周朗, 神吉智子, 水本輝彦, 早田学, 泉裕一郎, 柿添豊, 向山政志
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-17K09704
[Presentation] Intraglomerular crosstalk in a mouse model of diabetic nephropathy aggravated by the renin-angiotensin system activation2017
- Author(s)
  Shuro Umemoto, Takashige Kuwabara, Daisuke Fujimoto, Tomoko Kanki, Teruhiko Mizumoto, Yuichiro Izumi, Yutaka Kakizoe, Hirotaka Imamaki, Kiyoshi Mori, Masashi Mukoyama
- Organizer
  World Congress of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09268
[Presentation] Local inflammatory mechanism aggravated by intraglomerular crosstalk in diabetic kidney2017
- Author(s)
  Shuro Umemoto, Takashige Kuwabara, Daisuke Fujimoto, Tomoko Kanki, Teruhiko Mizumoto, Yutaka Kakizoe, Yuichiro Izumi, Kiyoshi Mori, Masashi Mukoyama
- Organizer
  Annual Meeting of the American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09268
[Presentation] Glomerular MRP8 expression predicts progression of proteinuria in obese or type 2 diabetic patients.2016
- Author(s)
  Takashige Kuwabara
- Organizer
  26th Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  COEX, Seoul, Korea
- Year and Date
  2016-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461226
[Presentation] Activation of the renin-angiotensin system in diabetic nephropathy induces local inflammation through intraglomerular crosstalk.2016
- Author(s)
  Takashige Kuwabara
- Organizer
  15th Asian Pacific Congress of Nephrolgy
- Place of Presentation
  Perth Convention and Exhibition Centre, Perth, Australia
- Year and Date
  2016-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461226
[Presentation] 慢性腎障害に対する穏和な全身温熱刺激による腎保護効果：5/6腎摘マウスにおける検討2016
- Author(s)
  岩下佳弘、桒原孝成、早田　学、柿添　豊、泉裕一郎、飯山準一、北村健一郎、向山政志、
- Organizer
  第39回日本高血圧学会
- Place of Presentation
  仙台市
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-15K01406
[Presentation] Myeloid-specific deletion of MRP8 ameliorates glomerulonephritis through affecting macrophage characterization.2016
- Author(s)
  Takashige Kuwabara
- Organizer
  Annual Meeting of the American Society of Nephrology
- Place of Presentation
  McCormick Place, Chicago, USA
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461226
[Presentation] シンポジウムポドサイトパチーupdate 「ポドサイトとS100ファミリー分子」2016
- Author(s)
  桒原孝成、梅本周郎、向山政志
- Organizer
  第46回日本腎臓学会西部学術大会
- Place of Presentation
  シーガイアコンベンションセンター、宮崎
- Year and Date
  2016-10-14
- Invited
- Data Source
  KAKENHI-PROJECT-15K09268
[Presentation] The role of activated renin-angiotensin system for the MRP8/TLR4 signaling in diabetic nephropathy.2016
- Author(s)
  Shuro Umemoto, Takashige Kuwabara, Hirotaka Imamaki, Manabu Hayata, Yuichiro Izumi, Yutaka Kakizoe, Kiyoshi Mori, Masashi Mukoyama
- Organizer
  The 26th Scientific Meeting of the International Society of Hypertension.
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09268
[Presentation] Myeloid-specific deletion of MRP8 ameliorates glomerulonephritis through affecting macrophage characterization.2016
- Author(s)
  Takashige Kuwabara, Kiyoshi Mori, Manabu Hayata, Shuro Umemoto, Hideki Yokoi, Masashi Mukoyama
- Organizer
  Annual meeting 2016 of the American Society of Nephrology
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09268
[Presentation] Intraglomerular crosstalk between mesangial cells and macrophages in glomerular injury.2016
- Author(s)
  Shuro Umemoto, Takashige Kuwabara, Manabu Hayata, Daisuke Fujimoto, Tomoko Kanki, Yutaka Kakizoe, Yuichiro Izumi, Masashi Mukoyama
- Organizer
  Annual meeting 2016 of the American Society of Nephrology
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09268
[Presentation] CKDモデルマウスに対するマイルドな全身温熱刺激の腎保護の可能性2016
- Author(s)
  岩下佳弘、桒原孝成、早田　学、柿添　豊、泉裕一郎、飯山準一、北村健一郎、向山政志、
- Organizer
  第21回阿蘇腎フォーラム
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-15K01406
[Presentation] 糖尿病マウスにおけるレニン・アンジオテンシン系亢進がMRP8/TLR4シグナルに与える影響およびその機序の検討2015
- Author(s)
  桒原孝成、今牧博貴、森　潔、横井秀基, 向山政志
- Organizer
  第38回日本高血圧学会総会
- Place of Presentation
  愛媛、ひめぎんホール
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K09268
[Presentation] 腎疾患および透析患者における慢性炎症の意義　～レニン・アンジオテンシン系阻害薬の効果と合わせて～2015
- Author(s)
  桒原孝成
- Organizer
  第21回日本HDF研究会学術総会
- Place of Presentation
  熊本、ホテル日航熊本
- Year and Date
  2015-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-15K09268
[Presentation] 骨髄細胞特異的MRP8欠損はマクロファージ形質を変化させることで糸球体腎炎を軽減する2015
- Author(s)
  桒原孝成、森　潔、横井秀基、笠原正登、柳田素子、向山政志
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋、名古屋国際会議場
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15K09268
[Presentation] Kidney myeloid-related protein 8 expression predicts renal prognosis in obese or type 2 diabetic patients.2015
- Author(s)
  Takashige Kuwabara
- Organizer
  The World Congress of Nephrology 2015
- Place of Presentation
  Cape Town International Convention Centre, Cape Town, South Africa
- Year and Date
  2015-03-14
- Data Source
  KAKENHI-PROJECT-26461226
[Presentation] Glomerular MRP8 expression predicts progression of proteinuria in obese or type 2 diabetic patients.2014
- Author(s)
  Takashige Kuwabara, Kiyoshi Mori, Hideki Yokoi, Shinji Yasuno, Masato Kasahara, Kenji Ueshima, Kazuwa Nakao, Masahito Imanishi, Akira Nishiyama, Motoko Yanagita, Masashi Mukoyama
- Organizer
  Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelaphia, USA
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-25860673
[Presentation] 糖尿病性腎症の治療薬を目指して「糖尿病性腎症における自然炎症の役割～MRP8/TLR4シグナル経路～」2012
- Author(s)
  桑原孝成
- Organizer
  協和発酵キリン腎臓シンポジウム
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-23790939
[Presentation] Macrophage-mediated glucolipotoxicity contributes to progression of diabetic nephropathy through MRP8/TLR4 signaling2012
- Author(s)
  Takashige Kuwabara
- Organizer
  Annual Meeting of American Society of Nephrology
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23790939
[Presentation] ワークショップ 3 糖尿病性腎症の新たな発症、進行メカニズム「自然免疫受容体 TLR4 が糖尿病性腎症進展に果たす役割-脂質による悪化-」2012
- Author(s)
  桑原孝成
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-02
- Data Source
  KAKENHI-PROJECT-23790939
[Presentation] 若手シンポジウム「炎症メディエーターMRP8/TLR4が糖尿病性腎症進展に果たす役割とは」2012
- Author(s)
  桑原孝成
- Organizer
  FRONT-J 第3回学術集会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23790939
[Presentation] ワークショップ3 糖尿病性腎症の新たな発症、進行メカニズム「自然免疫受容体TLR4が糖尿病性腎症進展に果たす役割-脂質による悪化-」2012
- Author(s)
  桑原孝成
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23790939
[Presentation] 若手シンポジウム「炎症メディエーターMRP8/TLR4 が糖尿病性腎症進展に果たす役割とは2012
- Author(s)
  桑原孝成
- Organizer
  FRONT-J 第3回学術集会
- Year and Date
  2012-08-11
- Data Source
  KAKENHI-PROJECT-23790939
[Presentation] Macrophage-mediated glucolipotoxicity contributes to progression of diabetic nephropathy through MRP8/TLR4 signaling2012
- Author(s)
  Kuwabara T
- Organizer
  Annual Meeting of American Society of Nephrology.
- Place of Presentation
  San Diego, USA
- Year and Date
  2012-11-02
- Data Source
  KAKENHI-PROJECT-23790939
[Presentation] Aggravation of diabetic nephropathy by hyperlipidemia is mediated by MRP8/TLR4 signaling in macrophages.2011
- Author(s)
  T Kuwabara, K Mori, M Mukoyama, et al.
- Organizer
  Annual Meeting of American Society of Nephrology
- Place of Presentation
  Philadelphia Convension Center, US
- Data Source
  KAKENHI-PROJECT-23790939
[Presentation] Toll-Like Recepotor 4-Mediated, Hyperinsulinemia-Independent Progression of Diabetic Nephropathy by Hyperlipidemia.2011
- Author(s)
  T Kuwabara, K Mori, M Mukoyama, et al.
- Organizer
  Annual Meeting of American Diabetes Association
- Place of Presentation
  San Diego Convension Center, US
- Data Source
  KAKENHI-PROJECT-23790939
[Presentation] Macrophage-mediated glucolipotoxicity via MRP8/TLR4 signaling in diabetic nephropathy
- Author(s)
  Takashige Kuwabara, Kiyoshi Mori, Masashi Mukoyama, Masato Kasahara, Hideki Yokoi, Hirotaka Imamaki, Akira Ishii, Kenichi Koga, Keita P Mori, Yukiko Kato, Akira Sugawara, Kazuwa Nakao
- Organizer
  Kidney and Lipids, World Congress of Nephrology, Satellite Synposium
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-25860673
[Presentation] 糖尿病性腎症進展に果たす自然炎症の役割とその活性化機序～脂質、RA系そして細胞間クロストーク～
- Author(s)
  桒原孝成、森潔、笠原正登、中尾一和、柳田素子、向山政志
- Organizer
  日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Invited
- Data Source
  KAKENHI-PROJECT-25860673
[Presentation] Role of chronic inflammation in diabetic nephropathy through glucolipotoxicity and intraglomerular crosstalk
- Author(s)
  Takashige Kuwabara, Kiyoshi Mori, Motoko Yanagita, Masashi Mukoyama
- Organizer
  The 3rd CKD Frontier Meeting
- Place of Presentation
  Nagoya, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-25860673

1. iiyama junichi (00398299)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
2. Iwashita Yoshihiro (70623510)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
3. MUKOYAMA Masashi (40270558)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
4. MORI Kiyoshi (60343232)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. NISHIYAMA Akira (10325334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Hayata Manabu (30646120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. IZUMI Yuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
8. Nishiyama Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. KASAHARA Masato

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. KADOMATSU Tsuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. MATSUBARA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. SHIMODAIRA Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 桑原宏一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 森泰生

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 中尾一和

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
16. 西田基宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 宮田敬士

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 横井秀基

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
19. 永芳友

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kuwabara Takashige 桑原 孝成

KUWABARA Takashige 桑原 孝成

Research Projects

Research Products

Co-Researchers

Role of MRP8 in the mechanism of acute kidney injury through cell-mediated immunityPrincipal Investigator

Principal Investigator

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Elucidation of the role of TRPV4 channel in the effect of repetitive hyperthermia on the progression of chronic kidney disease

Principal Investigator

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Role of renally expressed TRP channels in thermal preconditioning

Principal Investigator

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Role of MRP8 in the progression of glomerulonephritisPrincipal Investigator

Principal Investigator

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Elucidation of the mechanism of cisplatin-induced nephropathy reduction by thermal preconditioning

Principal Investigator

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The effects of systemic thermal habits on chronic kidney disease onset and progression and their underlying mechanisms elucidation

Principal Investigator

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Review Section

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Elucidation of the role of homeostatic inflammation in the AKI to CKD transition mechanism focusing on the time phase changes

Principal Investigator

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The role of MRP8 as a therapeutic target in chronic kidney diseasePrincipal Investigator

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Suppressive effects of mild sauna stimulation on chronic kidney disease progression

Principal Investigator

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Roles of humoral factors and organ-organ or cell-cell communications in the development and progression of metabolic kidney diseases

Principal Investigator

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The relationship between homeostatic inflammation and renin-angiotensin system in the progression of diabetic nephropathyPrincipal Investigator

Principal Investigator

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Research Institution

Novel mechanism of progression of diabetic nephropathy by hyperlipidemia: MRP8/TLR4 signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Book] 今日の治療指針 2024年版2024

Author(s)

Total Pages

Kuwabara Takashige 桑原孝成

KUWABARA Takashige 桑原孝成

[Book] 今日の治療指針　2024年版2024

[Book] 特集　腎と老化「老化と体液量調節機構」2016