Ueki Koujiro 植木浩二郎

… Alternative Names

UEKI Kohjiro 植木浩二郎

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Researcher Number	00396714
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立国際医療研究センター, 研究所, 糖尿病研究センター長
Affiliation (based on the past Project Information) *help	2023 – 2024: 国立研究開発法人国立国際医療研究センター, その他部局等, 糖尿病研究センター長 2020 – 2021: 国立研究開発法人国立国際医療研究センター, その他部局等, 糖尿病研究センター長 2016 – 2019: 東京大学, 医学部附属病院, 客員研究員 2018: 国立国際医療研究センター, 糖尿病研究センター長 2015: 東京大学, 医学部附属病院, 教授 … More 2013 – 2015: 東京大学, 医学部附属病院, 特任教授 2007 – 2012: The University of Tokyo, 医学部附属病院, 准教授 2009: 東京大学, 医学部附属病院, 特任准教授 2007 – 2008: The University of Tokyo, Faculty of Medicine, Associate Professor 2005 – 2006: 東京大学, 医学部附属病院, 特任助教授 2005: The University of Tokyo, Faculty of Medicine, Project Associate Professor, 医学部附属病院, 研究拠点形成特任助教授 2005: 東京大学, 医学部附属病院, 研究拠点形成特任教員(特任助教授) Less
Review Section/Research Field	Principal Investigator Metabolomics / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields Except Principal Investigator Metabolomics / Pathological medical chemistry
Keywords	Principal Investigator 糖尿病 / 肥満 / シグナル伝達 / インスリン / 老化 / インスリン抵抗性 / メタボリックシンドローム / Treatment / Diabetes / Hepatokine … More / Activin / FGF21 / LSEC / グルカゴン / Activin B / 体温調節 / 代謝 / 熱放散 / 糖代謝 / シングルセル解析 / 皮膚 / 腸内細菌 / LPS / マクロファージ / Akt / 骨格筋 / サルコペニア / トランスレーショナルリサーチ / インスリン分泌 / アディポカイン / 炎症 / 再生医学 / 脂質 / 糖 / 発言制御 … More Except Principal Investigator 糖尿病 / 肥満 / 受容体 / アディポカイン / PPAR / receptor / adipokine / 膵β細胞 / インスリン / 糖代謝 / AMPキナーゼ / インスリン抵抗性 / Mek/Erk経路 / インスリン分泌 / Mek/Erkシグナル / 膵島 / 細胞増殖 / 2型糖尿病 / MEK/ERKシグナル / メチル化 / RNA / RNA修飾 / 脂肪細胞分化 / diabetes / gene targeting / obesity / AMP kinase / insulin resistance / Diabetes / 遺伝子欠損マウス / カルモジュリン依存性キナーゼ / lRS-2 / 代償性肥大 / CaMK / CREB / IRS / 脂質代謝 / AdipoR / アディポネクチン / 動脈硬化症 / 血管内皮細胞 / インスリン受容体基質-2 / 好中球エラスターゼ Less

Development of a novel strategy for the treatment of diabetes through elucidation of the mechanism whereby Activin B controls glucose homeostasisPrincipal Investigator
- Principal Investigator
  
  植木浩二郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  National Center for Global Health and Medicine
Re-understanding of Systemic Metabolism through Skin-mediated Thermal RegulationPrincipal Investigator
- Principal Investigator
  
  Ueki Kohjiro
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  National Center for Global Health and Medicine
The Research for the Mechanism by Which RNA Methyl-Modification Regulates Adipocyte Differentiation
- Principal Investigator
  
  小林正稔
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Development of anti-diabetic therapy by the elucidation of the mechanism linking microflora and adipose tissue macrophagesPrincipal Investigator
- Principal Investigator
  
  Ueki Kohjiro
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Role of MEK/ERK signaling in pancreatic beta cells - to develop a novel treatment strategy for type 2 diaetes
- Principal Investigator
  
  Ikushima Yoshiko M
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Center for Global Health and Medicine
骨格筋のＡｋｔによる老化調節機構解明とサルコペニア・フレイルの画期的治療法の開発Principal Investigator
- Principal Investigator
  
  植木浩二郎
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Development of a novel anti-aging strategy by elucidating the mechanisms regulating aging through a muscle centric organ networkPrincipal Investigator
- Principal Investigator
  
  Ueki Kohjiro
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Elucidation of the role of FSTL3/Activin axis in the development of obesity-induced diabetesPrincipal Investigator
- Principal Investigator
  
  UEKI Kohjiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Exploring a novel therapeutic strategy for obesity-induced diabetes by suppressing Class IB PI3-kinase activityPrincipal Investigator
- Principal Investigator
  
  UEKI Kohjiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
肝臓での生理的小胞体ストレス調節とその破綻によるインスリン抵抗性惹起機構の解明Principal Investigator
- Principal Investigator
  
  植木浩二郎
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Integrated elucidation of metabolic pathway in the physiology and pathology
- Principal Investigator
  
  KADOWAKI Takashi
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Molecular biology of pancreatic islet β cell proliferation and failure
- Principal Investigator
  
  OHSUGI Mitsuru
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Study for the role of PI 3kinase in proliferation, regeneration and insulin secretion of pancreatic beta cellsPrincipal Investigator
- Principal Investigator
  
  UEKI Kohjiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
The roles of insulin receptor substrate-2 in the regulation of glucosehomeostasis and atherosclerosis
- Principal Investigator
  
  KUBOTA Naoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Physiological and pathophysiological roles ofAdiponectin receptors and identification of molecular targets for treatment of life-style related diseases
- Principal Investigator
  
  KADOWAKI Takashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
抗生活習慣病因子アディポネクチンの受容体アゴニスト・発現増加剤・切断活生化剤探索
- Principal Investigator
  
  YAMAUCHI Toshimasa
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
肝臓におけるSTAT3/SOCS3経路の調節による新しい糖脂質代謝改善療法の開発Principal Investigator
- Principal Investigator
  
  植木浩二郎
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Physiological and pathophysiological roles and signal transduction of adiponectin receptors
- Principal Investigator
  
  KADOWAKI Takashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo

[Book] 日本臨床2011
- Author(s)
  植木浩二郎
- Data Source
  KAKENHI-PROJECT-21390278
[Book] 実験医学2011
- Author(s)
  植木浩二郎、門脇孝
- Data Source
  KAKENHI-PROJECT-21390278
[Book] 糖尿病2011
- Author(s)
  植木浩二郎
- Data Source
  KAKENHI-PROJECT-21390278
[Book] 実験医学2010
- Author(s)
  植木浩二郎,門脇孝
- Data Source
  KAKENHI-PROJECT-21390278
[Book] 細胞2010
- Author(s)
  植木浩二郎
- Data Source
  KAKENHI-PROJECT-21390278
[Book] 糖尿病学20072007
- Author(s)
  植木浩二郎
- Total Pages
  148
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] IL-7R-Dependent Phosphatidylinositol 3-Kinase Competes with the STAT5 Signal to Modulate T Cell Development and Homeostasis.2020
- Author(s)
  Cui G, Shimba A, Ma G, Takahara K, Tani-Ichi S, Zhu Y, Asahi T, Abe A, Miyachi H, Kitano S, Hara T, Yasunaga JI, Suwanai H, Yamada H, Matsuoka M, Ueki K, Yoshikai Y, Ikuta K.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 204 Issue: 4 Pages: 844-857
- DOI
  10.4049/jimmunol.1900456
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07604, KAKENHI-PROJECT-19K16687, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-17K07166, KAKENHI-PLANNED-16H06496
[Journal Article] Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism2019
- Author(s)
  Sasako T., Ohsugi M., Kubota N., Itoh S., Okazaki Y, Terai A., Kubota T., Yamashita S., Nakatsukasa K., Kamura T., Iwayama K., Tokuyama K., Kiyonari H., Furuta Y., Shibahara J., Fukayama M., Enooku K., Okushin K., Tsutsumi T., Tateishi R., Tobe K., Asahara H., Koike K., *Kadowaki T. & *Ueki K.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1-16
- DOI
  10.1038/s41467-019-08591-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-17H03652, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-18H02860
[Journal Article] The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis.2018
- Author(s)
  Kobayashi M, Ohsugi M, Sasako T, Awazawa M, Umehara T, Iwane A, Kobayashi N, Okazaki Y, Kubota N, Suzuki R, Waki H, Horiuchi K, Hamakubo T, Kodama T, Aoe S, Tobe K, Kadowaki T, Ueki　K
- Journal Title
  
  Mol. Cell Biol.
  
  Volume: 38 Issue: 16 Pages: 81-91
- DOI
  10.1128/mcb.00116-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19556, KAKENHI-PROJECT-18K15075, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-16K09776, KAKENHI-PROJECT-17K09819, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-18H02860
[Journal Article] CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors2017
- Author(s)
  Nawaz Allah, , Usui Isao, , et al
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 286-301
- DOI
  10.1038/s41467-017-00231-1
- NAID
  120006535075
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09777, KAKENHI-PROJECT-17K08653, KAKENHI-PROJECT-17K09821, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-15K08527
[Journal Article] Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial2017
- Author(s)
  Ueki K, Sasako T, Okazaki Y, Kato M, Okahata S, Katsuyama H, Haraguchi M, Morita A, Ohashi K, Hara K, Morise A, Izumi K, Ishizuka N, Ohashi Y, Noda M, Kadowaki T
- Journal Title
  
  Lancet Diabetes Endocrinol
  
  Volume: 5 Issue: 12 Pages: 951-964
- DOI
  10.1016/s2213-8587(17)30327-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-15H04849
[Journal Article] Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity.2016
- Author(s)
  Kubota N, Kubota T, Kajiwara E, Iwamura T, Kumagai H, Watanabe T, Inoue M, Takamoto I, Sasako T, Kumagai K, Kohjima M, Nakamuta M, Moroi M, Sugi K, Noda T, Terauchi Y, Ueki K, Kadowaki T.
- Journal Title
  
  Nat Commun.
  
  Volume: 7 Issue: 1 Pages: 12977-12977
- DOI
  10.1038/ncomms12977
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04847, KAKENHI-PROJECT-16H05329, KAKENHI-PROJECT-16K15488, KAKENHI-PROJECT-26000012
[Journal Article] Tofogliflozin Improves Insulin Resistance in Skeletal Muscle and Accelerates Lipolysis in Adipose Tissue in Male Mice2016
- Author(s)
  Obata A, Kubota N, Kubota T, Iwamoto M, Sato H, Sakurai Y, Takamoto I, Katsuyama H, Suzuki Y, Fukazawa M, Ikeda S, Iwayama K, Tokuyama K, Ueki K and Kadowaki T
- Journal Title
  
  Endocrinology
  
  Volume: 157 Issue: 3 Pages: 1029-1042
- DOI
  10.1210/en.2015-1588
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-14J03079, KAKENHI-PROJECT-26000012
[Journal Article] Perspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in Obesity2015
- Author(s)
  Okada-Iwabu M, Iwabu M, Ueki K, Yamauchi T and Kadowaki T.
- Journal Title
  
  Diabetes Metab J
  
  Volume: 39 Issue: 5 Pages: 363-372
- DOI
  10.4093/dmj.2015.39.5.363
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-26713032, KAKENHI-PROJECT-26000012
[Journal Article] A Novel Peroxisome Proliferator-activated Receptor (PPAR)α Agonist and PPARγ Antagonist, Z-551, Ameliorates High-fat Diet-induced Obesity and Metabolic Disorders in Mice.2015
- Author(s)
  Shiomi Y, Yamauchi T, Iwabu M, Okada-Iwabu M, Nakayama R, Orikawa Y, Yoshioka Y, Tanaka K, Ueki K, Kadowaki T
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 23 Pages: 14567-14581
- DOI
  10.1074/jbc.m114.622191
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01507, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-23228001, KAKENHI-PROJECT-24249077, KAKENHI-PROJECT-26253058, KAKENHI-PROJECT-26282223, KAKENHI-PROJECT-26293216, KAKENHI-PROJECT-26713032, KAKENHI-PROJECT-26000012
[Journal Article] Insulin receptor substrate-2 (irs2) in endothelial cells plays a crucial role in insulin secretion2015
- Author(s)
  Hashimoto, S. Kubota, N. Sato, H. Sasaki, M. Takamoto, I. Kubota, T. Nakaya, K. Noda, M. Ueki, K. Kadowaki, T.
- Journal Title
  
  Diabetes
  
  Volume: 64 Issue: 3 Pages: 876-886
- DOI
  10.2337/db14-0432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249053, KAKENHI-PROJECT-24390232, KAKENHI-PROJECT-25461371, KAKENHI-PROJECT-26000012
[Journal Article] Ethnic differences in insulin sensitivity, beta-cell function, and hepatic extraction between Japanese and Caucasians: a minimal model analysis2014
- Author(s)
  Moller, J. B. Dalla Man, C. Overgaard, R. V. Ingwersen, S. H. Tornoe, C. W. Pedersen, M. Tanaka, H. Ohsugi, M. Ueki, K. Lynge, J. Vasconcelos, N. M. Pedersen, B. K. Kadowaki, T. Cobelli, C.
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 99 Issue: 11 Pages: 4273-4280
- DOI
  10.1210/jc.2014-1724
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249053, KAKENHI-PROJECT-26000012
[Journal Article] Deregulation of Pancreas-Specific Oxidoreductin ERO1beta in the Pathogenesis of Diabetes Mellitus2014
- Author(s)
  Awazawa, M. Futami, T. Sakada, M. Kaneko, K. Ohsugi, M. Nakaya, K. Terai, A. Suzuki, R. Koike, M. Uchiyama, Y. Kadowaki, T. Ueki, K.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 34 Issue: 7 Pages: 1290-1299
- DOI
  10.1128/mcb.01647-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249053, KAKENHI-PROJECT-25461373, KAKENHI-PROJECT-26000012
[Journal Article] A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity.2013
- Author(s)
  Okada-Iwabu M, Yamauchi T, Iwabu M, Honma T, Hamagami K, Matsuda K, Yamaguchi M, Tanabe H, Kimura-Someya T, Shirouzu M, Ogata H, Tokuyama K, Ueki K, Nagano T, Tanaka A, Yokoyama S and Kadowaki T.
- Journal Title
  
  Nature
  
  Volume: 503 Issue: 7477 Pages: 493-499
- DOI
  10.1038/nature12656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249053, KAKENHI-PROJECT-24700694, KAKENHI-PROJECT-25221307, KAKENHI-PROJECT-23689048, KAKENHI-PROJECT-24790908
[Journal Article] Snap Shot: Insulin Signaling Pathways2012
- Author(s)
  Kadowaki T, Ueki K, Yamauchi T, Kubota N.
- Journal Title
  
  Cep
  
  Volume: 148 Pages: 624-624
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Depletion of homeodomain-interacting protein kinase 3 impairs insulin secretion and glucose tolerance in mice2012
- Author(s)
  Shojima N, Hara K, Kubota N, Yamauchi T, Ueki K, Kadowaki T
- Journal Title
  
  Diabetologia
  
  Volume: 55 Issue: 12 Pages: 3318-3330
- DOI
  10.1007/s00125-012-2711-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] SnapShot: Physiology of Insulin Signaling2012
- Author(s)
  Kadowaki T, Kubota N, Ueki K, Yamauchi T
- Journal Title
  
  Ce11
  
  Volume: 148 Pages: 834-834
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Monocyte chemoattractant protein-1 (MCP-1) deficiency enhances alternatively activated M2 macrophages and ameliorates insulin resistance and fatty liver in lipoatrophic diabetic A-ZIP transgenic mice2012
- Author(s)
  Nio Y, Yamauchi T, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
- Journal Title
  
  Diabetologia
  
  Volume: 55 Issue: 12 Pages: 3350-3358
- DOI
  10.1007/s00125-012-2710-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-23689048, KAKENHI-PROJECT-24790908
[Journal Article] SnapShot : Physiology of Insulin Signaling2012
- Author(s)
  Kadowaki T, Kubota N, Ueki K, Yamauchi T
- Journal Title
  
  Cell
  
  Volume: 148 Issue: 4 Pages: 834-834
- DOI
  10.1016/j.cell.2012.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] SnapShot : Insulin Signaling Pathways2012
- Author(s)
  Kadowaki T, Ueki K, Yamauchi T, Kubota N
- Journal Title
  
  Cell
  
  Volume: 148 Issue: 3 Pages: 624-624
- DOI
  10.1016/j.cell.2012.01.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] The other sweet face of XBP-1.2011
- Author(s)
  Ueki K, Kadowaki T.
- Journal Title
  
  Nature Med.
  
  Volume: 17 Pages: 246-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] The other sweet face of XBP-12011
- Author(s)
  Ueki K, Kadowaki T
- Journal Title
  
  Nature Medicine
  
  Volume: 17 Issue: 3 Pages: 246-248
- DOI
  10.1038/nm0311-246
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage妖erived IL-6 dependent pathway2011
- Author(s)
  Awazawa M, Ueki K, Yamauchi T, Kubota, Kadowaki T
- Journal Title
  
  Cell Metabolism
  
  Volume: 13 Issue: 4 Pages: 401-412
- DOI
  10.1016/j.cmet.2011.02.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21390278, KAKENHI-PROJECT-23791019
[Journal Article] Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle.2011
- Author(s)
  Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itch S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki 0, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, TsutsuiM, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T.
- Journal Title
  
  Cell Metab.
  
  Volume: 13 Pages: 294-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Global mapping of cell type-specific open chromatin by FAIRE-seq reveals the regulatory role of the NFI family in adipocyte differentiation2011
- Author(s)
  Waki H, Nakamura M, Yamauchi T, Wakabayashi K, Yu J, Hirose-Yotsuya L, Take K, Sun W, Iwabu M, Okada-Iwabu M, Fujita T, Aoyama T, Tsutsumi S, Ueki K, Kodama T, Sakai J, Aburatani H, Kadowaki
- Journal Title
  
  PLos Genetics
  
  Volume: 7 Issue: 10 Pages: e1002311-e1002311
- DOI
  10.1371/journal.pgen.1002311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J03451, KAKENHI-PROJECT-20221009, KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-22229009, KAKENHI-PLANNED-23126101, KAKENHI-PROJECT-23791020, KAKENHI-PROJECT-23689048
[Journal Article] Impaired insulin signaling in the endothelial cells reduces insulin-induced glucose uptake by the skeletal muscle.2011
- Author(s)
  Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itoh S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki O, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, Tsutsui M, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T
- Journal Title
  
  Cell Metabolism 13
  
  Pages: 294-307
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle2011
- Author(s)
  Kubota T, Kubota N, Ueki K, Kadowaki T
- Journal Title
  
  Cell Metabolism
  
  Volume: 13 Pages: 294-307
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Blockade of class lB phosphor inositide-3 kinase ameliorates obesity induced inflammation and insulin resistance2011
- Author(s)
  Kobayashi N, Ueki, Kubota N, Hara K, Kadowaki T
- Journal Title
  
  Proc. Nat/. Acad. Sci. U.S.A.
  
  Volume: 108 Pages: 5753-5758
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via macrophage-derived IL-6 dependent pathway.2011
- Author(s)
  Awazawa M, Ueki K, Inabe K, Yamauchi T, Kubota N, Kaneko K, Kobayashi M, Iwane A, Sasako T, Ohsugi M, Takamoto I, Yamashita S, Asahara H, Akira S, Kasuga M, Kadowaki T
- Journal Title
  
  Cell Metabolism 13
  
  Pages: 401-412
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance2011
- Author(s)
  Kobayashi N, Ueki K, Okazaki Y, Iwane A, Kubota N, Ohsugi M, Awazawa M, Kobayashi M, Sasako T, Kaneko K, Suzuki M, Nishikawa Y, Hara K, Yoshimura K, Koshima I, Goyama s, Murakami K, Sasaki J, Nagai R, Kurokawa M, Sasaki T, Kadowaki T
- Journal Title
  
  Proc.Natl.Acad.Sci.USA
  
  Volume: 108 Issue: 14 Pages: 5753-5758
- DOI
  10.1073/pnas.1016430108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21200075, KAKENHI-PROJECT-21390278, KAKENHI-PROJECT-21591124
[Journal Article] Adiponectin and AdipoRl regulate PGCI and mitochondria by Ca^<2+> and AMPK/SIRTI.2010
- Author(s)
  Iwabu M, Yamauchi T, Okada-lwabu M, Sato K, Nakagawa T, Funata M, Pamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, .Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T
- Journal Title
  
  Nature
  
  Volume: 464 Pages: 1313-1319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT12010
- Author(s)
  Iwabu, M., Yamauchi, T., Okada-Iwabu, M., Sato, K., Nakagawa, T., Funata, M., Yamaguchi, M., Namiki, S., Nakayama, R., Tabata, M., Ogata, H., Kubota, N.,Takamoto, I., Hayashi, YK., Yamauchi, N., Waki, H., Fukayama, M., Nishino, I., Tokuyama, K., Ueki, K., Oike, Y., Ishii, S., Hirose, K., Shimizu, T., Touhara, K., and Kadowaki, T
- Journal Title
  
  Nature
  
  Volume: 464 Issue: 7293 Pages: 1313-1319
- DOI
  10.1038/nature08991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002011, KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21390278, KAKENHI-PROJECT-21680035, KAKENHI-PROJECT-22790244
[Journal Article] Adiponectin and AdipoR1 regulate PGC1・and mitochondria by Ca^<2+> and AMPK/SIRT1.2010
- Author(s)
  Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T
- Journal Title
  
  Nature 464
  
  Pages: 1313-1319
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation2010
- Author(s)
  Park S.W., Zhou Y., Lee J., Lu A., Sun C., Chung J., Ueki K., Ozcan U.
- Journal Title
  
  Nature Medicine 16
  
  Pages: 429-437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659227
[Journal Article] Class IA phosphatidylinositol 3-kinase in pancreatic b cells controls insulin secretion by multiple mechanisms.2010
- Author(s)
  Kaneko K, Ueki K, Takahashi N, Hashimoto S, Okamoto M, Awazawa M, Okazaki Y, Ohsugi M, Inabe K, Umehara T, Yoshida M, Kakei M, Kitamura T, Luo J, Kulkami RN, Kahn CR, Kasai H, Cantley LC, Kadowaki T
- Journal Title
  
  Cell Metabolism 12
  
  Pages: 619-632
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Decreased insulin secretion and accumulation of triglyceride in beta cells overexpressing a dominant-negative form of AMP-activated protein kinase.2010
- Author(s)
  Okazaki Y, Eto K, Yamashita T, Okamoto M, Ohsugi M, Noda M, Terauchi Y, Ueki K, Kadowaki T
- Journal Title
  
  Endocr J 57
  
  Pages: 141-52
- NAID
  130004443612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Class IA phosphatidylinositol 3-kinase in pancreatic b cells controls insulin secretion by multiple mechanisms.2010
- Author(s)
  Kaneko K, Ueki K, Takahashi N, Hashimoto S, Okamoto M, Awazawa M, Okazaki Y, Ohsugi M, Inabe K, Umehara T, Yoshida M, Kakei M, Kitamura T, Luo J, Kulkami RN, Kahn CR, Kasai H, Cantley LC, Kadowaki T
- Journal Title
  
  Cell Metab.
  
  Volume: 12 Pages: 619-632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Class IA phosphatidylinositol 3-kinase in pancreatic beta cells controls insulin secretion by multiple mechanisms2010
- Author(s)
  Kaneko K, Ueki K, Kadowaki T
- Journal Title
  
  Cell Metabolism
  
  Volume: 12 Issue: 6 Pages: 619-632
- DOI
  10.1016/j.cmet.2010.11.005
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Adiponectin and AdipoR1 regulate PGC-lalpha and mitochondria by Ca(2+) and AMPK/SIRT1.2010
- Author(s)
  Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T.
- Journal Title
  
  Nature (published online Mar.31, 2010)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response2010
- Author(s)
  Winnay J.N., Boucher J., Mori M.A., Ueki K., Kahn C.R
- Journal Title
  
  Nature Medicine 16
  
  Pages: 438-445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659227
[Journal Article] Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth2009
- Author(s)
  Torii S, Ueki K et al.
- Journal Title
  
  Diabetes 58
  
  Pages: 682-692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Regulation of calcium-permeable TRPV2 channel by insulin in pancreatic beta-cells.2009
- Author(s)
  Hisanaga E, Nagasawa M, Ueki K, Kulkarni RN, Mori M, Kojima I
- Journal Title
  
  Diabetes 58
  
  Pages: 174-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity2009
- Author(s)
  Nishimura S, Hara K, Ueki K, Kadowaki T
- Journal Title
  
  Nature Medicine
  
  Volume: 15 Issue: 8 Pages: 914-920
- DOI
  10.1038/nm.1964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21390278, KAKENHI-PROJECT-21390321
[Journal Article] Kulkarni RN, Takeuchi T : Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth.2009
- Author(s)
  Torii S, Saito N, Kawano A, Hou N, Ueki K
- Journal Title
  
  Diabetes 58
  
  Pages: 682-692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Kulkarni RN : Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate-2.2009
- Author(s)
  Assmann A, Ueki K, Winnay JN, Kadowaki T,
- Journal Title
  
  Mol Cell Biol 29
  
  Pages: 3219-3228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway.2009
- Author(s)
  Awazawa M, Ueki K, Inabe K, Yamauchi T, Kanako K, Okazaki Y, Bardeesy N, Ohnishi S, Nagai R, Kadowaki T
- Journal Title
  
  Biochem Biophys Res Commun 382
  
  Pages: 51-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Rimonabant amelio- rates insulin resistance via both adipo- nectin-dependent and adiponectin -independent pathways2009
- Author(s)
  atanabe T, Kubota N, Iwabu M, Yamauchi T, Ueki K, Kadowaki T
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 284 Issue: 3 Pages: 1803-1812
- DOI
  10.1074/jbc.m807120200
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] The death effector domain-containing DEDD supports S6K1 activity via preventing Cdk1-dependent inhibitory phosphorylation2009
- Author(s)
  Kurabe N, Arai S, Nishijima A, Kubota N, Suizu F, Mori M, Kurokawa J, Kondo-Miyazaki M, Ide T, Murakami K, Miyake K, Ueki K, Koga H, Yatomi Y, Tashiro F, Noguchi M, Kadowaki T, Miyazaki T.
- Journal Title
  
  J Biol Chem 284
  
  Pages: 5050-5055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases expression of very low density lipoprotein receptor gene in adipocytes2009
- Author(s)
  Takazawa T, Yamauchi T, Tsuchida A, Takata M, Hada Y, Iwabu M, Okada-Iwabu M, Ueki K and Kadowaki T
- Journal Title
  
  J Biol Chem
  
  Volume: 284 Issue: 44 Pages: 30049-30057
- DOI
  10.1074/jbc.m109.047993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390278
[Journal Article] Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases the expression of very low density lipoprotein receptor gene in adipocytes.2009
- Author(s)
  Takazawa T, Yamauchi T, Tsuchida A, Takata M, Hada Y, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
- Journal Title
  
  J Biol Chem 30
  
  Pages: 30049-30057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Regulation of calcium-permeable TRPV2 channel by insulin in pancreatic beta-cells2009
- Author(s)
  Hisanaga E, Ueki, K et al.
- Journal Title
  
  Diabetes 58
  
  Pages: 174-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] The Death Effector Domain-containing DEDD Supports S6K1 Activity via Preventing Cdk1-dependent Inhibitory Phosphorylation.2009
- Author(s)
  Kurabe N, Arai S, Nishijima A, Kubota N, Suizu F, Mori M, Kurokawa J, Kondo-Miyazaki M, Ide T, Murakami K, Miyake K, Ueki K, Koga H, Yatomi Y, Tashiro F, Noguchi M, Kadowaki T, Miyazaki T
- Journal Title
  
  J Biol Chem 284
  
  Pages: 5050-5055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Rimonabant ameliorates insulin resistance vla both adiponectin-dependent and adiponectin-independent pathways.2009
- Author(s)
  Watanabe T, Kubota N, Ohsugi M, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Yamauchi T, Noda T,Nagai R, Tcrauchi Y, Tobe K, Ueki K, Kadowaki T
- Journal Title
  
  J. Biol. Chem 284
  
  Pages: 1803-1812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways.2009
- Author(s)
  Watanabe T, Kubota N, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Yamauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadowaki T
- Journal Title
  
  J Biol Chem. 284(3)
  
  Pages: 1803-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591051
[Journal Article] Peroxisome proliferator-activated receptor gamma agonist rosiglitazone increases the expression of very low density lipoprotein receptor gene in adipocytes2009
- Author(s)
  Takazawa T, Yamauchi T, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 284 Pages: 30049-30057
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Reconsideration of insulin signals induced by improved laboratory animal diets, Japanese and American diets, in IRS-2 deficcient mice.2009
- Author(s)
  Hashimoto H, Arai T, Mori A, Kawai K, Hikishima K, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Okano H, Yamauchi T, Kubota N, Ueki K, Tobe K, Tamaoki N, Kadowaki T, Kosaka K
- Journal Title
  
  Exp Clin Endocrinol Diabetes 117
  
  Pages: 577-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Rimonabant ameliorates insulin resistance via both adiponectin-dependent and asiponectin-independent pathways2009
- Author(s)
  Watanabe T, Kubota N, Ohsugi M, Kubota T, Takammoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Ymauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadowaki T
- Journal Title
  
  J Biol Chem 284
  
  Pages: 1803-1812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate-2.2009
- Author(s)
  Assmann A, Ueki K et al
- Journal Title
  
  Mol Cell Biol (2009 Mar 9. Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Reconsideration of Insulin Signals Induced by Improved Laboratory Animal Diets, Japanese and American Diets, in IRS-2 Deficient Mice.2009
- Author(s)
  Hashimoto H, Arai T, Hikishima K, Ohnishi Y, Eto T, Ito M, Hioki K, Suzuki R, Ohsugi M, Saito M, Ueyama Y, Okano H, Yamauchi T, Kubota N, Ueki K, Tobe K, Tamaoki N, Kadowaki T, Kosaka K
- Journal Title
  
  Exp Clin Endocrinol Diabetes. 117(10)
  
  Pages: 577-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591051
[Journal Article] CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity.2009
- Author(s)
  Nishimura S, Manabe I, Nagasaki M, Eto K, Yamashita H, Ohsugi M, Otsu M, Hara K, Ueki K, Sugiura S, Yoshimura K, Kadowaki T, Nagai R
- Journal Title
  
  Nat Med 15
  
  Pages: 914-920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Dynamic Functional Relay between Insulin Receptor Substrate 1 and 2 in Hepatic Insulin Signaling during Fasting and Feeding2008
- Author(s)
  Kubota N,Ueki K,Kadowaki T et al.
- Journal Title
  
  Cell Metab 8
  
  Pages: 49-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Molecular Mechanism of Moderate Insulin Resistance in Adiponectin-Knockout Mice.2008
- Author(s)
  Yano W, Kubota N, Itoh S, Kubota T, Awazawa M, Moroi M, Sugi K, Takamoto I, Ogata H, Tokuyama K, Noda T, Terauchi Y, Ueki K, Kadowaki T
- Journal Title
  
  Endocr J 55
  
  Pages: 515-522
- NAID
  10021266439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding2008
- Author(s)
  Kubota N, Ueki K, Kadowaki T
- Journal Title
  
  Cell Metabolism
  
  Volume: 8 Issue: 1 Pages: 49-64
- DOI
  10.1016/j.cmet.2008.05.007
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance2008
- Author(s)
  Takamoto I, Kubota N, Ueki K,Kadowaki T et al.
- Journal Title
  
  Diabetes Obes Metab 10 Suppl 4
  
  Pages: 147-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance.2008
- Author(s)
  Takamoto I, Terauchi Y, Kubota N, Ohsugi M, Ueki K, Kadowaki T
- Journal Title
  
  Diabetes Obes Metab 10 Suppl 4
  
  Pages: 147-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Molecular mechanismof moderate insulin resistance in adiponectin-knockout mice2008
- Author(s)
  Yano W, Kubota N, Itoh S, Kubota T, Awazawa M, Moroi M, Sugi K, Takamoto I, Ogata H, Tokuyama K, Noda T, Terauchi Y, Ueki K, Kadowaki T.
- Journal Title
  
  Endocr. J. 55
  
  Pages: 515-522
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] The Death Effector Domain-containing DEDD Supports S6K1 Activity via Preventing Cdk1-dependent Inhibitory Phosphorylation2008
- Author(s)
  Kurabe N, Kubota N, Ueki K,Kadowaki T et al.
- Journal Title
  
  J Biol Chem 284
  
  Pages: 5050-5055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Dynamic Functional Relay between Insulin Receptor Substrate 1 and 2 in Hepatic Insulin Signaling during Fasting and Feeding.2008
- Author(s)
  Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T
- Journal Title
  
  Cell Metab 8
  
  Pages: 49-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Dynamic functional relay between insulin receptorsubstrate 1 and 2 in hepatic insulinsignaling during fasting and feeding2008
- Author(s)
  Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, OgataH, Tokuyama K, Ohsugi M, Sasako T, MoroiM, Sugi K, Kakuta S, Iwakura Y, Noda T,Ohnishi S, Nagai R, Tobe K, Terauchi Y,Ueki K, Kadowaki T.
- Journal Title
  
  Cell Metab. 8
  
  Pages: 49-64
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance.2008
- Author(s)
  Takamoto I, Terauchi Y, Kubota N, Ohsugi M, Ueki K, Kadowaki T
- Journal Title
  
  Diabetes Obes Metab. 10(Suppl 4)
  
  Pages: 147-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591051
[Journal Article] Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding2008
- Author(s)
  Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Ngai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T
- Journal Title
  
  Cell Metab 8
  
  Pages: 49-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] 5-Hydroxytryptamine 2A receptor signaling cascade modulates adiponectin and plasminogen activator inhibitor 1 expression in adipose tissue.2008
- Author(s)
  Uchida-Kitajima S, Ymauchi T, Takashina Y,Okada-Iwabu M, Iwabu M, Ueki K,Kadowaki T
- Journal Title
  
  FEBS Lett 582
  
  Pages: 3037-3044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding.2008
- Author(s)
  Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T
- Journal Title
  
  Cell Metabolism 8
  
  Pages: 49-64
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Crucial role ofinsulin receptor substrate-2 incompensatory beta-cell hyperplasia inresponse to high fat diet-inducedinsulin resistance2008
- Author(s)
  Takamoto I, Terauchi Y, Kubota N, OhsugiM, Ueki K, Kadowaki T.
- Journal Title
  
  Diabetes Obes. Metab. S4
  
  Pages: 147-156
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] Crucial role of IRS-2 in compensatory B-cell hyperplasia in response to high-fat-diet-induced insulin resistance.2008
- Author(s)
  Takamoto I, Terauchi Y, Kubota N, Kubota T. Ohsugi M, Ueki K, Kadowaki T
- Journal Title
  
  Diabetes, Obesity and Metabolism 10
  
  Pages: 147-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] Crucial role of insulin receptor substrate-2 in compensatory beta-cell hyperplasia in response to high fat diet-induced insulin resistance2008
- Author(s)
  Takamoto I, terauchi Y, Kubota N, Ohsugi M, ueki K, Kadowaki T
- Journal Title
  
  Diabetes Obes Metab 10
  
  Pages: 147-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008
[Journal Article] Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding.2008
- Author(s)
  Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T
- Journal Title
  
  Cell Metab. 8(1)
  
  Pages: 49-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591051
[Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T.
- Journal Title
  
  Cell Metab 6
  
  Pages: 55-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] The p85alpha regulatory subunit of phosphoinositide 3-kinase potentiates c-Jun N-terminal kinase-mediated insulin resistance.2007
- Author(s)
  Taniguchi CM, Aleman JO, Ueki K, Luo J, Asano T, Kaneto H, Stephanopoulos G, Cantley LC, Kahn CR
- Journal Title
  
  Mol Cell Biol 27
  
  Pages: 2830-2840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T
- Journal Title
  
  Cell Metab 6
  
  Pages: 55-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Targeted disruption of AdipoRl and AdipoR2 causes abrogation of adiponectin binding and metabohc actions2007
- Author(s)
  Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tbkuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
- Journal Title
  
  Nat Med 13
  
  Pages: 332-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007
- Author(s)
  窪田直人、植木浩二郎、門脇孝, 他
- Journal Title
  
  Cell Metabolism 6
  
  Pages: 55-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Adiponectin Stimulates AMP-ActivatedProtein Kinase in the Hypothalamus andIncreases Food Intake.2007
- Author(s)
  Kubota N, Yano W, Kubota T, YamauchiT, Itoh S, Kumagai H, Kozono H, TakamotoI, Okamoto S, Shiuchi T, Suzuki R, SatohH, Tsuchida A, Moroi M, Sugi K, Noda T,Ebinuma H, Ueta Y, Kondo T, Araki E,Ezaki O, Nagai R, Tobe K, Terauchi Y,Ueki K, Minokoshi Y, Kadowaki T
- Journal Title
  
  Cell Metab 6
  
  Pages: 55-68
- Data Source
  KAKENHI-PROJECT-19591037
[Journal Article] The p85alpha regulatory subunit of phosphoilositide 3-kinase potentiates c-Jun N-terrninal kilase-mediated insulin resistance2007
- Author(s)
  Cullen Taniguchi、植木浩二郎, 他
- Journal Title
  
  Mol Cell Biol 27
  
  Pages: 2830-2840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalam us and increases food intake.2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y,
- Journal Title
  
  Cell Metab. 6
  
  Pages: 55-68
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Targeted disruption ofAdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions2007
- Author(s)
  Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T.
- Journal Title
  
  Nat Med. 13
  
  Pages: 322-339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake2007
- Author(s)
  Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Mimokoshi Y, Ueki K,Minokoshi Y,Kadowaki T.
- Journal Title
  
  CeU Metab 6
  
  Pages: 55-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.2007
- Author(s)
  Horikoshi M, Hara K, Ito C, Shojima N, Nagai R, Ueki K, Froguel P, Kadowaki T
- Journal Title
  
  Diabetologia 50
  
  Pages: 2461-2466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population2007
- Author(s)
  堀越桃子、植木浩二郎、門脇孝, 他
- Journal Title
  
  Diabetologia 50
  
  Pages: 2461-2466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390247
[Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by Both Adiponectin-dependent and -independent Pathways.2006
- Author(s)
  Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Is hikawa M, Moroi M, Sugi K, Ya mauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 8748-8755
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome2006
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
- Journal Title
  
  J. Clin. Invest 116
  
  Pages: 1784-1792
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.2006
- Author(s)
  Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K.
- Journal Title
  
  J. Clin. Invest. 116
  
  Pages: 1784-1792
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Pioglitazone Ameliorates Insulin Resistance and Diabetes by-Both Adiponectin-dependent and-independent Pathways2006
- Author(s)
  Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Ishikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 8748-8755
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance2006
- Author(s)
  Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 26602-26614
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance.2006
- Author(s)
  Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Tsunoda M, Id
- Journal Title
  
  J. Bio1. Chem. 281
  
  Pages: 26602-26614
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209033
[Journal Article] Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome2005
- Author(s)
  Ueki, K et al.
- Journal Title
  
  Hepatol Res 33, 2
  
  Pages: 185-192
- Data Source
  KAKENHI-PROJECT-17659275
[Presentation] 骨格筋のインスリンシグナルと個体老化2020
- Author(s)
  笹子敬洋, 山内敏正, 門脇孝, 植木浩二郎
- Organizer
  第34回日本糖尿病・肥満動物学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 膵β細胞制御におけるMek/Erkシグナルの役割の解明2019
- Author(s)
  生島芳子，小林直樹，粟澤元晴，諏訪内浩紹，添田光太郎，村谷匡史，高橋倫子，植木浩二郎
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K19067
[Presentation] Role of Akt in skeletal muscle in the protection of sarcopenia and aging2019
- Author(s)
  Takayoshi Sasako, Takashi Kadowaki, Kohjiro Ueki
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 糖尿病合併 NASH における血糖とインスリンによる腸内細菌叢の変化2019
- Author(s)
  添田光太郎，小林直樹，生島芳子，笹子敬洋，戸田郷太郎，粟澤元晴，門脇孝，植木浩二郎
- Organizer
  第33日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K19067
[Presentation] The role of insulin signaling in the protection of sarcopenia and frailty2019
- Author(s)
  Kohjiro Ueki
- Organizer
  International Diabetes Federation
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] Role of insulin signaling in sarcopenia2019
- Author(s)
  Kohjiro Ueki
- Organizer
  5th Asian Conference for Frailty and Sarcopenia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 骨格筋のインスリン・Aktシグナルによる代謝・老化制御機構2019
- Author(s)
  植木浩二郎
- Organizer
  第92回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] Mek/Erkシグナルは膵β細胞の量と分泌能を制御する2019
- Author(s)
  生島芳子、小林直樹、粟澤元晴、竹宮聖一、諏訪内浩紹、添田光太郎、守本祐一、村谷匡史、高橋倫子、植木浩二郎
- Organizer
  第33日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K19067
[Presentation] 心筋におけるAktの役割の解明2018
- Author(s)
  添田光太郎，小林直樹，生島芳子，戸田郷太郎，笹子敬洋，竹宮聖一，野田哲生，門脇孝，植木浩二郎
- Organizer
  第 61 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K19067
[Presentation] 骨格筋のインスリン・Aktシグナルによる代謝・老化制御2018
- Author(s)
  植木浩二郎
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] サルコペニア肥満における骨格筋インスリン/Aktシグナルの役割2018
- Author(s)
  植木浩二郎
- Organizer
  第39回日本肥満学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] Role of Akt in skeletal muscle in the protection of sarcopenia and aging2018
- Author(s)
  Takayoshi Sasako, Takashi Kadowaki, and Kohjiro Ueki
- Organizer
  第91回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 骨格筋のインスリン・Aktによる老化制御2018
- Author(s)
  植木浩二郎
- Organizer
  第5回日本サルコペニア・フレイル学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] Role of Akt in skeletal muscle in anti-aging2018
- Author(s)
  Kohjiro Ueki
- Organizer
  RECQ 2018 (Invited speaker at symposium)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 骨格筋におけるAktの活性低下がインスリン抵抗性とサルコペニアに及ぼす作用の検討2017
- Author(s)
  笹子敬洋, 戸田郷太郎, 添田光太郎, 門脇孝, 植木浩二郎
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 骨格筋のAktによる老化制御機構2017
- Author(s)
  植木浩二郎
- Organizer
  第35回日本骨粗鬆症学会学術集会（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 骨格筋におけるAktの活性低下がインスリン抵抗性とサルコペニアに及ぼす作用の検討2017
- Author(s)
  笹子敬洋, 梅原敏弘, 戸田郷太郎, 添田光太郎, 門脇孝, 植木浩二郎
- Organizer
  第54回日本臨床分子医学会学術集会（学術奨励賞）
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 骨格筋におけるAktの活性低下がインスリン抵抗性とサルコペニアに及ぼす作用の検討2017
- Author(s)
  笹子敬洋, 戸田郷太郎, 添田光太郎, 門脇孝, 植木浩二郎
- Organizer
  第90回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 骨格筋のインスリン・Aktシグナルによる代謝・老化制御機構2017
- Author(s)
  植木浩二郎
- Organizer
  第60回日本糖尿病学会年次学術集会（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] Akt activity in skeletal muscle prevents sarcopenia and premature aging in mice2017
- Author(s)
  Kohjiro Ueki
- Organizer
  2nd Asian Conference for Frailty and Sarcopneia (Invited speaker at symposium)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] Role of Akt in skeletal muscle in the protection of sarcopenia and aging2017
- Author(s)
  Kohjiro Ueki
- Organizer
  12th International Symposium of Geriatrics and Gerontology
- Place of Presentation
  大府市
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 糖尿病患者のサルコペニア・フレイル2017
- Author(s)
  植木浩二郎
- Organizer
  第32回日本糖尿病合併症学会（教育講演）
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] サルコぺニアの成因と予防2016
- Author(s)
  植木浩二郎
- Organizer
  第25回日本交通医学工学研究会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 骨髄系細胞におけるAktを介した代謝恒常性維持機構の検討2016
- Author(s)
  戸田郷太郎、笹子敬洋、亀井望、添田光太郎、諏訪内浩紹、坂田道教、小林正稔、岡崎由希子、鈴木亮、松本佐保姫、眞鍋一郎、戸邉一之、Morris J. Birnbaum、門脇孝、植木浩二郎
- Organizer
  第59回日本糖尿病肥満動物学会
- Place of Presentation
  京都市
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16K15488
[Presentation] 骨格筋におけるAktの活性低下がインスリン抵抗性とサルコペニアに及ぼす作用2016
- Author(s)
  笹子敬洋, 戸田郷太郎, 添田光太郎, 門脇孝, 植木浩二郎
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都市
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 糖尿病患者の筋機能と糖代謝2016
- Author(s)
  植木浩二郎
- Organizer
  第51回日本理学療法学術大会
- Place of Presentation
  横浜市
- Year and Date
  2016-05-27
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 骨格筋におけるAktの活性低下がインスリン抵抗性とサルコペニアに及ぼす作用の検討2016
- Author(s)
  笹子敬洋, 戸田郷太郎, 添田光太郎, 門脇孝, 植木浩二郎
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  京都市
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] Role of Akt in Skeletal Muscle in Anti-Aging2016
- Author(s)
  Kohjiro Ueki
- Organizer
  Annual Meeting of the Korean Society for Molecular and Cellular Biology
- Place of Presentation
  Seoul
- Year and Date
  2016-10-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 骨格筋のAktシグナルによる老化制御2016
- Author(s)
  植木浩二郎
- Organizer
  第2回日本筋学会学術集会
- Place of Presentation
  東京都
- Year and Date
  2016-08-05
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] Akt signaling in muscle plays a key role in the maintenance of a healthy long life2016
- Author(s)
  植木浩二郎
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都市
- Year and Date
  2016-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] サルコペニアの発症メカニズムとその予防2016
- Author(s)
  植木浩二郎
- Organizer
  第66回日本体質医学会学術集会
- Place of Presentation
  和歌山市
- Year and Date
  2016-09-03
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] Akt activity in skeletal muscle prevents sarcopenia and premature aging in mice2016
- Author(s)
  Kohjiro ueki
- Organizer
  2nd Asian Conference for Frailty and Sarcopenia
- Place of Presentation
  名古屋市
- Year and Date
  2016-11-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] インスリン・IGF-1シグナルを介した筋骨格系制御メカニズム2016
- Author(s)
  笹子敬洋, 門脇孝, 植木浩二郎
- Organizer
  第34回日本骨代謝学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2016-07-20
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] 肥満と老化に克つ糖尿病治療を考える2015
- Author(s)
  植木浩二郎
- Organizer
  日本体質医学会総会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2015-07-04
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] インスリン・IGF-1シグナルと老化・寿命制御2015
- Author(s)
  植木浩二郎
- Organizer
  日本抗加齢医学会講習会
- Place of Presentation
  サンケイプラズ（東京都・千代田区）
- Year and Date
  2015-12-20
- Invited
- Data Source
  KAKENHI-PROJECT-15H05789
[Presentation] ヒト脂肪組織発現解析を用いた病態特異的アディポカインの検索2014
- Author(s)
  岡﨑由希子、岩根亜弥、小林直樹、笹子敬洋、諏訪内浩紹、小林正稔、原一雄、窪田直人、山内敏正、門脇孝、植木浩二郎
- Organizer
  第19回日本肥満学会主催　アディポサイエンス・シンポジウム
- Place of Presentation
  豊中市
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-24249053
[Presentation] Molecular mechanisms involved in obesity-induced diabetes2014
- Author(s)
  Kohjiro Ueki
- Organizer
  DEBATE 2014
- Place of Presentation
  Hotel Le Meridien, Bangalore, India
- Invited
- Data Source
  KAKENHI-PROJECT-24249053
[Presentation] 肥満症治療の課題と展望2013
- Author(s)
  植木浩二郎
- Organizer
  第63回日本体質医学会総会
- Place of Presentation
  久留米大学筑水会館、久留米
- Invited
- Data Source
  KAKENHI-PROJECT-24249053
[Presentation] ヒト脂肪組織発現解析を用いた病態特異的アディポカインの検索2013
- Author(s)
  岡崎由希子、岩根亜弥、笹子敬洋、坂田道教、諏訪内浩紹、小林正稔、原一雄、窪田直人、門脇孝、植木浩二郎
- Organizer
  第34回日本肥満学会年次学術集会
- Place of Presentation
  東京国際フォーラム、東京
- Data Source
  KAKENHI-PROJECT-24249053
[Presentation] Identification of a novel adipokine involved in the development of the Metabolic Syndrome2013
- Author(s)
  Yukiko Okazaki, Kohjiro Ueki, Aya Iwane, Takayoshi Sasako, Michinori Sakada, Toshihiro Umehara, Hirotsugu Suwanai, Masatoshi Kobayashi, Motoharu Awazawa, Naoki Kobayashi, Kazuo Hara, Matthias Blueher, Takashi Kadowaki
- Organizer
  73th Scientific Sessions of the American Diabetes Association
- Place of Presentation
  The Moscone Center, Chicago, USA
- Data Source
  KAKENHI-PROJECT-24249053
[Presentation] ヒト脂肪組織発現解析を用いた病態特異的アディポカインの検索2013
- Author(s)
  岡崎由希子、植木浩二郎、岩根亜弥、笹子敬洋、坂田道教、諏訪内浩紹、小林直樹、小林正稔、大杉満、窪田直人、原一雄、山内敏正、吉村浩太郎、光嶋勲、油谷浩幸、門脇　孝
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本、熊本
- Data Source
  KAKENHI-PROJECT-24249053
[Presentation] Role of fat2013
- Author(s)
  Kohjiro Ueki
- Organizer
  World Diabetes Congress 2013
- Place of Presentation
  Melbourne Convention and Exhibition Centre, Melbourne, Australia
- Invited
- Data Source
  KAKENHI-PROJECT-24249053
[Presentation] 2型糖尿病updateー成因と病態2012
- Author(s)
  植木浩二郎
- Organizer
  第85回日本内分泌学会総会
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-24249053
[Presentation] 成因と病態に基づく糖尿病治療を考える2012
- Author(s)
  植木浩二郎
- Organizer
  第62回日本体質医学会総会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-24249053
[Presentation] 脂肪組織における急性炎症経路と慢性炎症経路によるインスリン感受性の調節2012
- Author(s)
  植木浩二郎
- Organizer
  第26回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  名古屋(招待講演)
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] 脂肪組織における急性炎症経路と慢性炎症経路によるインスリン感受性の調節2012
- Author(s)
  植木浩二郎
- Organizer
  第26回日本糖尿病・肥満動物学会年次学術集会(シンポジウム)
- Place of Presentation
  名古屋
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] インスリン抵抗性の分子基盤2011
- Author(s)
  植木浩二郎
- Organizer
  第32回日本肥満学会
- Place of Presentation
  淡路島(招待講演)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] 生理的一過性および慢性持続性ストレス経路によるインスリン感受性の制御機構2011
- Author(s)
  植木浩二郎
- Organizer
  第84回日本生化学会大会(シンポジウム)
- Place of Presentation
  京都
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] インスリン抵抗性の分子基盤2011
- Author(s)
  植木浩二郎
- Organizer
  第32回日本肥満学会(教育講演)
- Place of Presentation
  淡路島
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] Inflammatory response and insulin sensitivity2011
- Author(s)
  Kohjiro Ueki
- Organizer
  The 2011 Seoul Symposium on Obesity and Diabetes(Symposium)
- Place of Presentation
  韓国・ソウル
- Year and Date
  2011-04-09
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] Inflammatory response and insulin sensitivity2011
- Author(s)
  植木浩二郎
- Organizer
  The 2011 Seoul Symposium on Obesity and Diabetes
- Place of Presentation
  ソウル(韓国)(招待講演)
- Year and Date
  2011-04-09
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] 生理的一過性および慢性持続性ストレス経路によるインスリン感受性の制御機構2011
- Author(s)
  植木浩二郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] 摂食に伴う肝臓での小胞体ストレスのインスリン感受性に及ぼす作用の検討用の検討2010
- Author(s)
  笹子敬洋, 大杉満, 窪田直人, 戸邊一之, 植木浩二郎, 門脇孝
- Organizer
  第83回日本内分泌学会学術集会(若手研究奨励賞)
- Place of Presentation
  京都市
- Year and Date
  2010-03-25
- Data Source
  KAKENHI-PROJECT-21659227
[Presentation] 膵島IRS-2量調節の分子機構:肥満・糖尿病モデルにおけるIRS-2量2010
- Author(s)
  勝山修行、大杉満、窪田直人、植木浩二郎、門脇孝
- Organizer
  第3回日本肥満症治療学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-20591051
[Presentation] 膵島IRS-2量調節の分子機構1:肥満・糖尿病モデルにおけるIRS-2量2010
- Author(s)
  勝山修行、大杉満、窪田直人、植木浩二郎、門脇孝
- Organizer
  第53回日本糖尿病学会学術総会
- Place of Presentation
  岡山(口頭発表)
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-20591051
[Presentation] Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca2+ signalling and AMPK/SIRT1 like exercise.2010
- Author(s)
  Yamauchi T, Iwabu M, Okada-Iwabu M, Ueki K, Kadowaki T
- Organizer
  46^<th> Annual Meeting of the European Association for the Study of Diabetes.
- Place of Presentation
  Stockholm
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20229008
[Presentation] Regulation of insulin sensitivity through changes in expression of adipokines by obesity2010
- Author(s)
  植木浩二郎
- Organizer
  シンポジウム
- Place of Presentation
  岡山
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] Regulation of insulin sensitivity through changes in expression of adipokines by obesity2010
- Author(s)
  植木浩二郎
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山市
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] Impact of feeding-induced hepatic ER stress on the regulation of insulin sensitivity2010
- Author(s)
  Sasako, T., Ueki K., Ohsugi M., Kubota N., Tobe K., Kadowaki T.
- Organizer
  The 14th International Congress of Endocrinology
- Place of Presentation
  京都市
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21659227
[Presentation] 摂食に伴う肝臓での小胞体ストレスのインスリン感受性に及ぼす作用の検討用の検討2010
- Author(s)
  笹子敬洋, 大杉満, 窪田直人, 戸邉一之, 植木浩二郎, 門脇孝
- Organizer
  第24回日本糖尿病・肥満動物学会(若手研究奨励賞)
- Place of Presentation
  大阪市
- Year and Date
  2010-01-22
- Data Source
  KAKENHI-PROJECT-21659227
[Presentation] Adiponectin and AdipoRl regulate PGC-lalpha and mitochondria by Ca^<2+> signalling and AMPK/SIRTl like exercise.2010
- Author(s)
  Yamauchi T. Iwabu M. Okada-Iwabu M, Ueki K, Kadowaki T
- Organizer
  6^<th>Annual Meeting of the European Association for the Study of Diabetes.
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20229008
[Presentation] 膵島IRS-2量調節の分子機構:分子メカニズム2010
- Author(s)
  大杉満、勝山修行、窪田直人、植木浩二郎、門脇孝
- Organizer
  第3回日本肥満症治療学会学術集会
- Place of Presentation
  東京(口頭発表)
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-20591051
[Presentation] Insulin resistance and NASH/NAFLD2010
- Author(s)
  Kohjiro Ueki
- Organizer
  The 9th JSH single topic conference(Symposium)
- Place of Presentation
  東京
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] 膵島IRS-2量調節の分子機構2:分子メカニズム2010
- Author(s)
  大杉満、勝山修行、窪田直人、植木浩二郎、門脇孝
- Organizer
  第53回日本糖尿病学会学術総会
- Place of Presentation
  岡山(口頭発表)
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-20591051
[Presentation] Insulin resistance and NASH/NAFLD2010
- Author(s)
  植木浩二郎
- Organizer
  The 9^<th> JSH single topic conference
- Place of Presentation
  東京都
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] 膵島代償性増殖とその破綻における膵島IRS-2量調節の分子機構:糖代謝の重要性2009
- Author(s)
  勝山修行、大杉満、窪田直人、戸邉一之、小林正稔、笹子敬洋、金子和真、植木浩二郎、門脇孝
- Organizer
  第52回日本糖尿病学会学術総会
- Place of Presentation
  大阪(口頭発表)
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20591051
[Presentation] 膵β細胞におけるインスリンシグナルの役割2009
- Author(s)
  植木浩二郎、門脇孝
- Organizer
  第23 回日本糖尿病・肥満動物学会年次学術集会シンポジウム
- Place of Presentation
  岡山
- Year and Date
  2009-02-14
- Data Source
  KAKENHI-PROJECT-19390247
[Presentation] 肥満糖尿病におけるClass IB PI3キナーゼの役割2009
- Author(s)
  植木浩二郎、小林直樹、門脇孝
- Organizer
  第82回日本内分泌学会学術総会シンポジウム(公募)
- Place of Presentation
  前橋市
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] 肥満糖尿病におけるClass IB PI3キナーゼの役割2009
- Author(s)
  植木浩二郎
- Organizer
  82回日本内分泌学会学術総会(シンポジウム)
- Place of Presentation
  前橋
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] Class 1B PI3キナーゼ制御による肥満糖尿病治療の可能性の検討割2009
- Author(s)
  植木浩二郎
- Organizer
  第52回日本糖尿病学会年次学術集会(シンポジウム)
- Place of Presentation
  大阪
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] 血管内皮細胞におけるインスリン受容体基質(IRS)2の役割の解明-血管内皮細胞特異的IRS2欠損マウスを用いて-2009
- Author(s)
  窪田哲也,窪田直人,山口真一,井上真理子,植木浩二郎,門脇孝
- Organizer
  第23回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  岡山
- Year and Date
  2009-02-13
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] Impact of Sdf2l1, a novel ER stress-related protein, on the regulation of hepatic insulin resistance2009
- Author(s)
  Sasako, T., Ueki K., Ohsugi M., Kubota N., Tobe K., Kadowaki T.
- Organizer
  The 69th Scientific Sessions of the American Diabetes Association
- Place of Presentation
  米国ニューオリンズ市
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-21659227
[Presentation] 膵島代償性増殖とその破綻における膵島IRS-2量調節の分子機構2009
- Author(s)
  大杉満、窪田直人、小林正稔、笹子敬洋、金子和真、勝山修行、植木浩二郎、門脇孝
- Organizer
  第59回日本体質医学会総会
- Place of Presentation
  東京(口頭発表)
- Year and Date
  2009-07-26
- Data Source
  KAKENHI-PROJECT-20591051
[Presentation] Class 1B PI3キナーゼ制御による肥満糖尿病治療の可能性の検討割2009
- Author(s)
  植木浩二郎、小林直樹、門脇孝
- Organizer
  第82回日本生化学会大会シンポジウム(招待)
- Place of Presentation
  神戸市
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] 新規小胞体ストレス調節因子Sdf2l1による肝臓でのインスリン感受性調節作用の検討2009
- Author(s)
  笹子敬洋, 大杉満, 窪田直人, 戸邊一之, 植木浩二郎, 門脇孝
- Organizer
  第82回日本内分泌学会学術集会
- Place of Presentation
  前橋市
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21659227
[Presentation] Class 1B PI3キナーゼ制御による肥満糖尿病治療の可能性の検討割2009
- Author(s)
  植木浩二郎
- Organizer
  第30回日本肥満学会(シンポジウム)
- Place of Presentation
  浜松
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] 膵 β 細胞におけるインスリンシグナルの役割2009
- Author(s)
  植木浩二郎、門脇孝
- Organizer
  第23回日本糖尿病・肥満動物学会年次学術集会シンポジゥム
- Place of Presentation
  岡山
- Year and Date
  2009-02-14
- Data Source
  KAKENHI-PROJECT-19390247
[Presentation] 膵島代償性増殖とその破綻における膵島IRS-2量調節の分子機構:CaMキナーゼ4転写因子CREBの役割2009
- Author(s)
  大杉満、窪田直人、戸邉一之、小林正稔、笹子敬洋、金子和真、勝山修行、植木浩二郎、門脇孝
- Organizer
  第52回日本糖尿病学会学術総会
- Place of Presentation
  大阪(口頭発表)
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20591051
[Presentation] Class 1B PI3キナーゼ制御による肥満糖尿病治療の可能性の検討割2009
- Author(s)
  植木浩二郎
- Organizer
  第82回日本生化学会大会(シンポジウム)
- Place of Presentation
  神戸
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] Impact of feeding-induced hepatic ER stress on the regulation of insulin sensitivity2009
- Author(s)
  Sasako, T., Ueki K., Ohsugi M., Kubota N., Tobe K., Kadowaki T.
- Organizer
  The 15th Korea-Japan Symposium on Diabetes Mellitus
- Place of Presentation
  韓国済州島
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-21659227
[Presentation] Class 1B PI3キナーゼ制御による肥満糖尿病治療の可能性の検討割2009
- Author(s)
  植木浩二郎、小林直樹、門脇孝
- Organizer
  第30回日本肥満学会シンポジウム(招待)
- Place of Presentation
  浜松市
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] Class 1B PI3キナーゼ制御による肥満糖尿病治療の可能性の検討割2009
- Author(s)
  植木浩二郎、小林直樹、門脇孝
- Organizer
  第52回日本糖尿病学会年次学術集会シンポジウム(招待)
- Place of Presentation
  大阪市
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-21390278
[Presentation] Insulin signaling defect in endothelial cells causesskeletal muscle insulin resistance2008
- Author(s)
  Kubota N, Kubota T, Kumagai H, Yamauchi T, Ueki K, Kadowaki T
- Organizer
  第40回日本動脈硬化学会総会・学術集会
- Place of Presentation
  茨城
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] 肝臓の糖代謝におけるIRS-1、IRS-2の役割の検討2008
- Author(s)
  窪田直人,窪田哲也,伊藤晋介,山内敏正,植木浩二郎,門脇孝
- Organizer
  第13回アディポサイエンス研究会
- Place of Presentation
  大阪
- Year and Date
  2008-08-22
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding.2008
- Author(s)
  Kubota N, Kubota T, Yamauchi T, Ueki K, Kadowaki T
- Organizer
  The 4th Scientific Meeting of Asia-Pacific Diabetes and Obesity Study Group
- Place of Presentation
  Japan(Osaka)
- Year and Date
  2008-08-20
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] GlucoseEB-IR Pathway isponsible for the Failure of Compensatory β Hyperplasia in the Pogression to Diabetes.2008
- Author(s)
  Mitsuru Ohsugi, Naoto Kubota, Kohjiro Ueki, Takashi Kadowaki
- Organizer
  American Diabetes Association Annual Scientific Sessions
- Place of Presentation
  San Francisco, CA, USA(Oral Presentation)
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20591051
[Presentation] 膵β細胞におけるClass IA PI3 キナーゼの役割2008
- Author(s)
  金子和真、植木浩二郎、門脇孝
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京(oral session)
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19390247
[Presentation] Insulin signaling in endothelial cells participates in the regulation of skeletal muscle insulin sensitivity2008
- Author(s)
  Kubota T, Kubota N, Kozono H, Takahashi T, Itoh S, Ueki K, Kadowaki T
- Organizer
  Scientific Sessions 68th American Diabetes Association
- Place of Presentation
  San Francisco
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] 日本人におけるインスリン抵抗性と膵島機能不全2008
- Author(s)
  植木浩二郎
- Organizer
  第42回糖尿病学の進歩
- Place of Presentation
  高松
- Year and Date
  2008-02-15
- Data Source
  KAKENHI-PROJECT-19390247
[Presentation] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding.2008
- Author(s)
  Kubota N, Kubota T, Yamauchi T, Ueki K, Kadowaki T
- Organizer
  The 1st Insulin Resistance in Metabolic Disease Forum
- Place of Presentation
  Japan(Osaka)
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] Dynamic functional relay between insulin receptor substrate-1 and -2 in hepatic insulin signaling during fasting and feeding2008
- Author(s)
  Kubota N, Kubota T, Itoh S Terauchi Y,Ueki K, Kadowaki T
- Organizer
  Scilentific Sessions 68th American Diabetes Association
- Place of Presentation
  San Frandisco
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] 日本人におけるインスリン抵抗性と膵島機能不全2008
- Author(s)
  植木浩二郎
- Organizer
  第42 回糖尿病学の進歩シンポジウム
- Place of Presentation
  高松
- Year and Date
  2008-02-15
- Data Source
  KAKENHI-PROJECT-19390247
[Presentation] Role of Class 1A PI3 kinase in pancreatic beta cells2008
- Author(s)
  金子和真、植木浩二郎、門脇孝
- Organizer
  第68回アメリカ糖尿病学会
- Place of Presentation
  サンフランシスコろ(oral session)
- Year and Date
  2008-06-08
- Data Source
  KAKENHI-PROJECT-19390247
[Presentation] IRS-2欠損膵β細胞株の樹立2008
- Author(s)
  高本偉碩,窪田直人,橋本信嗣,峯山智佳,窪田哲也,伊藤晋介,山内敏正,植木浩二郎,宮崎純一,門脇孝
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] 膵β細胞におけるClass IA PI3キナーゼの役割2008
- Author(s)
  金子和真、植木浩二郎、門脇孝
- Organizer
  第51回日本糖尿病学会年次学術集会 (oral session)
- Place of Presentation
  東京
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19390247
[Presentation] Role of Class 1A PI3 kinase in pancreatic beta cells2008
- Author(s)
  金子和真、植木浩二郎、門脇孝
- Organizer
  第68回アメリカ糖尿病学会 (oral session)
- Place of Presentation
  サンフランシスコ
- Year and Date
  2008-06-08
- Data Source
  KAKENHI-PROJECT-19390247
[Presentation] インスリン抵抗性発症における血管と骨格筋のネットワーク機構の解明2008
- Author(s)
  窪田哲也,窪田直人,熊谷洋紀,小園秀樹,高橋雄大,杉薫,山内敏正,植木浩二郎,門脇孝
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19591037
[Presentation] 膵β細胞におけるClass IA PI3キナーゼの役割2007
- Author(s)
  金子和真、植木浩二郎、門脇孝
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19390247
[Presentation] 膵β細胞におけるClass IA PI3 キナーゼの役割2007
- Author(s)
  金子和真、植木浩二郎、門脇孝
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台(oral session)
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19390247
[Presentation] Role of Class 1A PI3 kinase in pancreatic beta cells2007
- Author(s)
  金子和真、植木浩二郎、門脇孝
- Organizer
  第67回アメリカ糖尿病学会
- Place of Presentation
  シカゴ(oral session)
- Year and Date
  2007-06-24
- Data Source
  KAKENHI-PROJECT-19390247
[Presentation] Role of Class 1A PI3 kinase in pancreatic beta cells2007
- Author(s)
  金子和真、植木浩二郎、門脇孝
- Organizer
  第67回アメリカ糖尿病学会
- Place of Presentation
  シカゴ
- Year and Date
  2007-06-22
- Data Source
  KAKENHI-PROJECT-19390247
[Presentation] ヒト脂肪組織発現解析を用いた病態特異的アディポカインの検索
- Author(s)
  岡﨑由希子、岩根亜弥、小林直樹、笹子敬洋、諏訪内浩紹、小林正稔、戸田郷太郎、添田光太郎、澤田知伸、坂田道教、原一雄、窪田直人、山内敏正、門脇孝、植木浩二郎
- Organizer
  第29回日本糖尿病合併症学会
- Place of Presentation
  千代田区
- Year and Date
  2014-10-03 – 2014-10-04
- Data Source
  KAKENHI-PROJECT-24249053
[Presentation] 肥満と老化に抗して生活習慣病に克つ
- Author(s)
  植木浩二郎
- Organizer
  第32回内分泌代謝学サマーセミナー
- Place of Presentation
  河口湖町
- Year and Date
  2014-07-10 – 2014-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-24249053
[Presentation] ヒト脂肪組織発現解析を用いた病態特異的アディポカインの検索
- Author(s)
  岡崎由希子、岩根亜弥、笹子敬洋、坂田道教、諏訪内浩紹、梅原敏弘、小林直樹、小林正稔、窪田直人、原　一雄、山内敏正、吉村浩太郎、光嶋勲、油谷浩幸、門脇　孝、植木浩二郎
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪市
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24249053
[Presentation] Activin/FSTL3による糖代謝制御機構
- Author(s)
  岡崎由希子、岩根亜弥、小林直樹、笹子敬洋、諏訪内浩紹、小林正稔、窪田直人、山内敏正、原　一雄、門脇　孝、植木浩二郎
- Organizer
  第29回日本糖尿病・肥満動物学会年次学術集会
- Place of Presentation
  京都市
- Year and Date
  2015-02-13 – 2015-02-14
- Invited
- Data Source
  KAKENHI-PROJECT-24249053
[]

1. KADOWAKI Takashi (30185889)

# of Collaborated Projects: 10 results

# of Collaborated Products: 104 results
2. YAMAUCHI Toshimasa (40372370)

# of Collaborated Projects: 7 results

# of Collaborated Products: 39 results
3. KUBOTA Naoto (50396719)

# of Collaborated Projects: 7 results

# of Collaborated Products: 72 results
4. TOBE Kazuyuki (30251242)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
5. HARA Kazuo (50359600)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
6. SUWANAI Hirotsugu (60624939)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
7. SASAKO Takayoshi (20550429)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
8. KOBAYASI Masatoshi (30396725)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
9. Kobayashi Naoki (80750728)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
10. Awazawa Motoharu (90466764)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. OHSUGI Mitsuru (00420216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
12. OKAZAKI Yukiko (30422299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. Ikushima Yoshiko M (00571366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. Muratani Masafumi (50730199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. HARA Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. USUI Isao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 清水孝雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 中務邦雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ueki Koujiro 植木 浩二郎

UEKI Kohjiro 植木 浩二郎

Research Projects

Research Products

Co-Researchers

Development of a novel strategy for the treatment of diabetes through elucidation of the mechanism whereby Activin B controls glucose homeostasisPrincipal Investigator

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Re-understanding of Systemic Metabolism through Skin-mediated Thermal RegulationPrincipal Investigator

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Development of anti-diabetic therapy by the elucidation of the mechanism linking microflora and adipose tissue macrophagesPrincipal Investigator

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骨格筋のＡｋｔによる老化調節機構解明とサルコペニア・フレイルの画期的治療法の開発Principal Investigator

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Development of a novel anti-aging strategy by elucidating the mechanisms regulating aging through a muscle centric organ networkPrincipal Investigator

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Elucidation of the role of FSTL3/Activin axis in the development of obesity-induced diabetesPrincipal Investigator

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Exploring a novel therapeutic strategy for obesity-induced diabetes by suppressing Class IB PI3-kinase activityPrincipal Investigator

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肝臓での生理的小胞体ストレス調節とその破綻によるインスリン抵抗性惹起機構の解明Principal Investigator

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Study for the role of PI 3kinase in proliferation, regeneration and insulin secretion of pancreatic beta cellsPrincipal Investigator

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Principal Investigator

Ueki Koujiro 植木浩二郎

UEKI Kohjiro 植木浩二郎