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Ichise Taeko  市瀬 多恵子

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ICHISE Taeko  市瀬 多恵子

市瀬 多恵子  イチセ タエコ

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Researcher Number 00396863
Other IDs
Affiliation (Current) 2025: 琉球大学, 医学部, ポスドク研究員
Affiliation (based on the past Project Information) *help 2020 – 2025: 琉球大学, 病院, ポスドク研究員
2018 – 2019: 琉球大学, 医学部, 委託非常勤講師
2010 – 2017: 東京大学, 医科学研究所, 助教
2007: 東京大学, 医科学研究所, 助教
2005 – 2006: 東京大学, 医科学研究所, 助手
Review Section/Research Field
Principal Investigator
Basic Section 56070:Plastic and reconstructive surgery-related / Experimental pathology / Basic Section 49030:Experimental pathology-related / General anatomy (including Histology/Embryology)
Except Principal Investigator
Basic Section 56070:Plastic and reconstructive surgery-related / General anatomy (including histology/embryology) / Laboratory animal science / Biological Sciences
Keywords
Principal Investigator
マウス / CBP/p300 / ケラチノサイト / Ras / リンパ管 / Designer Cells / 内皮間葉移行 / リンパ管内皮細胞 / 移植 / リンパ浮腫 … More / 脂肪間質細胞 / アセチル化 / 上皮性腫瘍 / p300 / CBP / 皮膚 / EGFR / RalGEF経路 / PI3キナーゼ経路 / MAPキナーゼ経路 / 血小板 / 巨核球 / Cre/loxP / VEGFR-3 / PLC-gamma2 / Prox1 / Proxl … More
Except Principal Investigator
リンパ管 / マウス / トランスジェニックマウス / 三次元的形態解析 / リンパ管内皮 / リンパ浮腫 / オルガネラ / 脂肪間質細胞 / リンパ管内皮細胞 / MAPキナーゼ / 皮膚表皮 / RalGEF / PI3キナーゼ / Raf / 表皮 / 内皮間葉移行 / Erk / Ras / 部位特異的組換え酵素 / Dre/rox / FLP/FRT / Cre/loxP / SV40 tsA58T抗原 / 内皮細胞 / 血管 / Angiopoietin-2 / VEGF-C Less
  • Research Projects

    (11 results)
  • Research Products

    (41 results)
  • Co-Researchers

    (4 People)
  •  3Dリンパ管ネットワークシートを用いたリンパ浮腫治療法の開発Principal Investigator

    • Principal Investigator
      市瀬 多恵子
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      University of the Ryukyus
  •  Optimizing lymphatic vessel regeneration through adipose-derived stromal cell-mediated organelle transfer

    • Principal Investigator
      市瀬 広武
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      University of the Ryukyus
  •  Three-dimensional Morphological Visualization of Human Collective Lymphatic Vessels to Elucidate Lymphedema Mechanisms

    • Principal Investigator
      鈴木 悠史
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Keio University
  •  リンパ浮腫治療のための脂肪間質細胞改変型”Designer Cells”の開発Principal Investigator

    • Principal Investigator
      市瀬 多恵子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      University of the Ryukyus
  •  Exploring CBP/p300-dependent EGFR signaling to develop a method to control skin homeostasisPrincipal Investigator

    • Principal Investigator
      Ichise Taeko
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      University of the Ryukyus
  •  Elucidating the role of Ras downstream pathways in hair and skin developmentPrincipal Investigator

    • Principal Investigator
      Ichise Taeko
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      University of the Ryukyus
      The University of Tokyo
  •  Elucidating the role of Ras downstream pathways and Ras signal strength in angio/lymphangiogenesis and epidermal morphogenesis

    • Principal Investigator
      ICHISE Hirotake
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      The University of Tokyo
  •  Generation of multi-step, site-specific recombination system in vivo

    • Principal Investigator
      ICHISE Hirotake
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo
  •  Analysis of the mechanism of blood cell- and bone marrow-derivedcell-induced separation of the blood and lymphatic vasculaturePrincipal Investigator

    • Principal Investigator
      ICHISE Taeko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      The University of Tokyo
  •  トランスジェニックマウスを用いたVEGF-CおよびAng-2の機能解析

    • Principal Investigator
      YOSHIDA Nobuaki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  リンパ管におけるホメオボックス転写因子Proxlの機能解析Principal Investigator

    • Principal Investigator
      市瀬 多恵子
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo

All 2023 2022 2020 2019 2018 2016 2014 2012 2011 2010 Other

All Journal Article Presentation Book

  • [Book] よくわかるリンパ浮腫のすべて (分担執筆)2011

    • Author(s)
      市瀬 広武 (光嶋 勲 編著)
    • Publisher
      永井書店
    • Data Source
      KAKENHI-PROJECT-22590187
  • [Book] よくわかるリンパ浮腫のすべて2011

    • Author(s)
      市瀬 広武(光嶋 勲 編著)
    • Total Pages
      6
    • Publisher
      永井書店
    • Data Source
      KAKENHI-PROJECT-22500384
  • [Book] よくわかるリンパ浮腫のすべて(分担執筆)2011

    • Author(s)
      市瀬広武(光嶋勲編著)
    • Total Pages
      6
    • Publisher
      永井書店
    • Data Source
      KAKENHI-PROJECT-22500384
  • [Book] よくわかるリンパ浮腫のすべて2011

    • Author(s)
      市瀬広武,光嶋 勲
    • Total Pages
      213
    • Publisher
      永井書店
    • Data Source
      KAKENHI-PROJECT-22590187
  • [Journal Article] CBP/p300 antagonises EGFR‐Ras‐Erk signalling and suppresses increased Ras‐Erk signalling‐induced tumour formation in mice2019

    • Author(s)
      Ichise Taeko、Yoshida Nobuaki、Ichise Hirotake
    • Journal Title

      The Journal of Pathology

      Volume: 印刷中 Issue: 1 Pages: 39-51

    • DOI

      10.1002/path.5279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08418, KAKENHI-PROJECT-18K07039
  • [Journal Article] Phospholipase Cγ2 Is Required for Luminal Expansion of the Epididymal Duct during Postnatal Development in Mice.2016

    • Author(s)
      Ichise H, Ichise T, Yoshida N.
    • Journal Title

      PLoS One

      Volume: 11 Issue: 3 Pages: e0150521-e0150521

    • DOI

      10.1371/journal.pone.0150521

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08418, KAKENHI-PROJECT-25460263
  • [Journal Article] Establishment of a tamoxifen-inducible Cre-driver mouse strain for widespread and temporal genetic modification in adult mice2016

    • Author(s)
      Hirotake Ichise, Akiko Hori, Seiji Shiozawa, Saki Kondo, Yumi Kanegae, Izumu Saito, Taeko Ichise, and Nobuaki Yoshida
    • Journal Title

      Exp. Anim.

      Volume: 65 Issue: 3 Pages: 231-244

    • DOI

      10.1538/expanim.15-0126

    • NAID

      130006882370

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19105, KAKENHI-PROJECT-25460263, KAKENHI-PROJECT-26670221, KAKENHI-PROJECT-15K08418
  • [Journal Article] FGF2-induced Ras-MAPK signalling maintains lymphatic endothelial cell identity by upregulating endothelial-cell-specific gene expression and suppressing TGFβ signalling through Smad2.2014

    • Author(s)
      Ichise, T., Yoshida, N., Ichise, H.
    • Journal Title

      Journal of Cell Science

      Volume: 127 Pages: 845-857

    • DOI

      10.1242/jcs.137836

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460263
  • [Journal Article] The Cd6 gene as a permissive locus for targeted transgenesis in the mouse.2014

    • Author(s)
      Ichise, H., Ichise, T., Sasanuma, H., Yoshida, N.
    • Journal Title

      genesis

      Volume: 52 Issue: 5 Pages: 440-450

    • DOI

      10.1002/dvg.22779

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460263
  • [Journal Article] Ras/MAPK Signaling Modulates VEGFR-3 Expression through Ets-Mediated p300 Recruitment and Histone Acetylation on the Vegfr3 Gene in Lymphatic Endothelial Cells.2012

    • Author(s)
      Ichise, T., Yoshida, N., Ichise, H.
    • Journal Title

      PLoS One.

      Volume: 7 Issue: 12 Pages: e51639-e51639

    • DOI

      10.1371/journal.pone.0051639

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500384, KAKENHI-PROJECT-22590187
  • [Journal Article] Y.Platelet activation receptor CLEC-2 regulates blood/lymphatic vessel separation by inhibiting proliferation, migration, and tube formation of lymphatic endothelial cells.2012

    • Author(s)
      Osada, M., Inoue, O., Ding, G., Shirai, T., Ichise, H., Hirayama, K., Takano, K., Yatomi, Y., Hirashima, M., Fujii, H., Suzuki-Inoue, K., Ozaki
    • Journal Title

      The Journal of biological chemistry.

      Volume: 287 Issue: 26 Pages: 22241-22252

    • DOI

      10.1074/jbc.m111.329987

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500384, KAKENHI-PROJECT-22590187, KAKENHI-PROJECT-23591984
  • [Journal Article] リンパ管新生におけるRasの役割2010

    • Author(s)
      市瀬広武
    • Journal Title

      リンパ学

      Volume: 33 Pages: 102-106

    • URL

      http://mol.medicalonline.jp/archive/search-jo=ed6lymph&ye=2010&vo=33&issue=2

    • Data Source
      KAKENHI-PROJECT-22590187
  • [Journal Article] リンパ管新生におけるRasの役割2010

    • Author(s)
      市瀬 広武
    • Journal Title

      リンパ学

      Volume: 33 Pages: 102-106

    • URL

      http://mol.medicalonline.jp/archive/search?jo=ed6lymph&ye=2010&vo=33&issue=2

    • Data Source
      KAKENHI-PROJECT-22500384
  • [Journal Article] Nucleoredoxin sustains Wnt/β-catenin signaling by retaining a pool of in active dishevelled protein.2010

    • Author(s)
      Funato Y, Terabayashi T, Sakamoto R, Okuzaki D, Ichise H, Nojima H, Yoshida N, Miki H.
    • Journal Title

      Current Biology

      Volume: 20 Pages: 1945-1952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500384
  • [Journal Article] N., Miki, H.Nucleoredoxin sustains Wnt/β-catenin signaling by retaining a pool of inactive Dishevelled protein.2010

    • Author(s)
      Funato, Y., Terabayashi, T., Sakamoto, R., Okuzaki, D., Ichise, H., Nojima, H.,Yoshida
    • Journal Title

      Current biology.

      Volume: 20 Issue: 21 Pages: 1945-1952

    • DOI

      10.1016/j.cub.2010.09.065

    • Data Source
      KAKENHI-PROJECT-22500384, KAKENHI-PROJECT-22590187
  • [Journal Article] Nucleoredoxin negatively regulates Toll-like receptor 4 signaling via recruitment of flightless-I to myeloid differentiation primary response gene (88).2010

    • Author(s)
      Hayashi, T., Funato, Y., Terabayashi, T., Morinaka, A., Sakamoto, R., Ichise, H., Fukuda, H., Yoshida, N., Miki, H.
    • Journal Title

      The Journal of biological chemistry.

      Volume: 285 Issue: 24 Pages: 18586-18593

    • DOI

      10.1074/jbc.m110.106468

    • Data Source
      KAKENHI-PROJECT-22500384, KAKENHI-PROJECT-22590187
  • [Presentation] リンパ管内皮細胞の内皮間葉移行抑制による浮腫軽減効果の検討2023

    • Author(s)
      市瀬多恵子、市瀬広武、清水雄介
    • Organizer
      第66回日本形成外科学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-22K09885
  • [Presentation] 細胞動態可視化マウス脂肪間質細胞の作製と利用2023

    • Author(s)
      市瀬多恵子、市瀬広武、清水雄介
    • Organizer
      第32回日本形成外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-22K09885
  • [Presentation] リンパ浮腫におけるリンパ管内皮細胞の内皮間葉移行2022

    • Author(s)
      市瀬多恵子、市瀬広武、清水雄介
    • Organizer
      日本形成外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-22K09885
  • [Presentation] トランスジェニックアリルを利用したマウス内皮細胞の選択的培養法2020

    • Author(s)
      市瀬 広武、市瀬多恵子
    • Organizer
      日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-18K07039
  • [Presentation] CBP/p300はマウスにおいて表皮ケラチノサイトのがん化を抑制する2019

    • Author(s)
      市瀬 広武、市瀬 多恵子
    • Organizer
      日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-18K07039
  • [Presentation] マウスを用いた内皮・上皮の形態形成機構の解析2019

    • Author(s)
      市瀬 広武
    • Organizer
      九州実験動物研究会
    • Data Source
      KAKENHI-PROJECT-18K07039
  • [Presentation] CBP/p300 suppresses increased Ras-Erk signaling-induced tumor formation in mice.2019

    • Author(s)
      Ichise H.
    • Organizer
      The 78th Annual Meeting of the Japanese Cancer Association.
    • Data Source
      KAKENHI-PROJECT-18K07039
  • [Presentation] CBP/p300はマウス表皮ケラチノサイトの癌化を抑制する2018

    • Author(s)
      市瀬 広武
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K08418
  • [Presentation] CBP/p300はマウス表皮ケラチノサイトの癌化を抑制する2018

    • Author(s)
      市瀬 広武
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07039
  • [Presentation] マウスでの標的遺伝子導入に適したpermissive lociの探索2018

    • Author(s)
      市瀬 広武、市瀬 多恵子、吉田 進昭
    • Organizer
      第65回日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-18K07039
  • [Presentation] マウスでの標的遺伝子導入に適したpermissive lociの探索2018

    • Author(s)
      市瀬 広武、市瀬 多恵子、吉田 進昭
    • Organizer
      第65回日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-15K08418
  • [Presentation] CRISPR/Cas9システムを用いたGFPレポーターノックインマウスの作成と解析2016

    • Author(s)
      橋本 寛子、市瀬 多恵子、菊池 美緒、市瀬 広武、吉田 進昭
    • Organizer
      第16回 東京大学生命科学シンポジウム
    • Place of Presentation
      日本・東京
    • Year and Date
      2016-04-23
    • Data Source
      KAKENHI-PROJECT-15K08418
  • [Presentation] PLCγ2はマウスにおいて生後の精巣上体管の管腔拡張に必須である2016

    • Author(s)
      市瀬 広武、市瀬 多恵子、吉田 進昭
    • Organizer
      第39回 日本分子生物学会年会
    • Place of Presentation
      日本・横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15K08418
  • [Presentation] CRISPR/Cas9を用いたGFPレポーターノックインマウスの作成と解析2016

    • Author(s)
      橋本 寛子、市瀬 多恵子、菊池 美緒、市瀬 広武、吉田 進昭
    • Organizer
      第28回 高遠・分子細胞生物学シンポジウム
    • Place of Presentation
      日本・長野県
    • Year and Date
      2016-08-25
    • Data Source
      KAKENHI-PROJECT-15K08418
  • [Presentation] 表皮形成におけるp300/CBPの役割2016

    • Author(s)
      市瀬 多恵子、吉田 進昭、市瀬 広武
    • Organizer
      第39回 日本分子生物学会年会
    • Place of Presentation
      日本・横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15K08418
  • [Presentation] A Modulatory Role of Ras in VEGFR-3 Signalling during Normal and Pathological Lymphangiogenesis"2011

    • Author(s)
      Hirotake Ichise
    • Organizer
      第32回日本炎症・再生医学会シンポジウム "Tumor Microenvironment and Inflammation"
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2011-06-02
    • Data Source
      KAKENHI-PROJECT-22500384
  • [Presentation] A Modulatory Role of Ras in VEGFR-3 Signalling during Normal and Pathological Lymphangiogenesis2011

    • Author(s)
      Hirotake Ichise
    • Organizer
      第32回日本炎症・再生医学会
    • Place of Presentation
      国立京都国際会館(京都)(招待講演)
    • Year and Date
      2011-06-02
    • Data Source
      KAKENHI-PROJECT-22500384
  • [Presentation] A Modulatory Role of Ras in VEGFR-3Signalling during Normal and PathologicalLymphangiogenesis2011

    • Author(s)
      Hirotake Ichise
    • Organizer
      第32回 日本炎症・再生医学会シンポジウム "Tumor Microenvironment and Inflammation"
    • Place of Presentation
      国立京都国際会館,京都
    • Year and Date
      2011-06-02
    • Data Source
      KAKENHI-PROJECT-22590187
  • [Presentation] Role of Ras in lymphangiogenesis"Gordon Research Conference 2010,2010

    • Author(s)
      Hirotake Ichise
    • Organizer
      Molecular Mechanisms in Lymphatic Function & Disease
    • Place of Presentation
      Lucca (Barga), Italy(招待講演)
    • Year and Date
      2010-06-15
    • Data Source
      KAKENHI-PROJECT-22500384
  • [Presentation] Role of Ras in lymphangiogenesis Gordon Research Conference 20102010

    • Author(s)
      Hirotake Ichise
    • Organizer
      Molecular Mechanisms in Lymphatic Function & DiseaseJune 15
    • Place of Presentation
      Lucca (Barga), Italy
    • Data Source
      KAKENHI-PROJECT-22590187
  • [Presentation] リンパ管新生におけるRasの役割2010

    • Author(s)
      市瀬広武
    • Organizer
      第34回日本リンパ学会総会
    • Place of Presentation
      東京大学山上会館
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-22590187
  • [Presentation] リンパ管新生におけるRasの役割2010

    • Author(s)
      市瀬広武
    • Organizer
      第34回日本リンパ学会総会
    • Place of Presentation
      東京大学山上会館,東京
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-22590187
  • [Presentation] リンパ管新生における Ras の役割2010

    • Author(s)
      市瀬 広武
    • Organizer
      第34回日本リンパ学会総会
    • Place of Presentation
      東京大学山上会館(東京)
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-22500384
  • [Presentation] Role of Ras in lymphangiogenesis2010

    • Author(s)
      Hirotake Ichise
    • Organizer
      Gordon Research Conference 2010 "Molecular Mechanisms in Lymphatic Function & Disease"
    • Place of Presentation
      Lucca (Barga), Italy
    • Year and Date
      2010-06-15
    • Data Source
      KAKENHI-PROJECT-22590187
  • [Presentation] Modulatory Role of Ras in VEGFR-3 Signalling during Normal and Pathological Lymphangiogenesis

    • Author(s)
      Hirotake Ichise
    • Organizer
      第32回 日本炎症・再生医学会
    • Place of Presentation
      国立京都国際会館(京都)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22590187
  • 1.  ICHISE Hirotake (10313090)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 40 results
  • 2.  清水 雄介 (10327570)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 3.  YOSHIDA Nobuaki (10250341)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  鈴木 悠史 (40793287)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results

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この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

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