KOIKE NOBUYA 小池宣也

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Koike Nobuya 小池宣也

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Researcher Number	00399685
Other IDs
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 講師
Affiliation (based on the past Project Information) *help	2024: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2019 – 2022: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2017: 京都府立医科大学, 医学研究科, 講師 2014 – 2016: 京都府立医科大学, 医学(系)研究科(研究院), 講師
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Environmental physiology(including physical medicine and nutritional physiology) Except Principal Investigator Environmental physiology(including physical medicine and nutritional physiology)
Keywords	Principal Investigator 体内時計 / 概日リズム / 時計遺伝子 / 光環境周期攪乱 / エンハンサー / エピジェネティック / クロマチンリモデリング / ES細胞 / クロマチンアクセシビリティ / 概日時計 … More / エピゲノム / 生理学 / 制限給餌 / メタボリズム / トランスクリプトーム … More Except Principal Investigator 発生 / 体内時計 / 概日リズム / 発生発達 / 生物時計 / 環境生理学 Less

Analysis of pre-symptomatic pathophysiology in chronic jet-lag mouse modelPrincipal Investigator
- Principal Investigator
  
  小池宣也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Epigenetic analysis for emergence of mammalian circadian rhythmsPrincipal Investigator
- Principal Investigator
  
  Koike Nobuya
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Developmental mechanisms of circadian clock in mouse embryo
- Principal Investigator
  
  YAGITA Kazuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Kyoto Prefectural University of Medicine
Circadian transcriptome analysis for protection against obesity developmentPrincipal Investigator
- Principal Investigator
  
  Koike Nobuya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Kyoto Prefectural University of Medicine

All 2023 2022 2021 2020 2019 2017 2016 2015

All Journal Article Presentation Patent

[Journal Article] Circadian Features of Cluster Headache and Migraine: A Systematic Review, Meta-analysis, and Genetic Analysis2023
- Author(s)
  Benkli Barlas、Kim Sun Young、Koike Nobuya、Han Chorong、Tran Celia、Silva Emma、Yan Yuanqing、Yagita Kazuhiro、Chen Zheng、Yoo Seung-Hee、Burish Mark Joseph
- Journal Title
  
  Neurology
  
  Volume: 10 Issue: 22
- DOI
  10.1212/wnl.0000000000207240
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-19K06770, KAKENHI-PROJECT-22K18366
[Journal Article] The Polymethoxyflavone Sudachitin Modulates the Circadian Clock and Improves Liver Physiology2023
- Author(s)
  Mawatari Kazuaki、Koike Nobuya、Nohara Kazunari、Wirianto Marvin、Uebanso Takashi、Shimohata Takaaki、Shikishima Yasuhiro、Miura Hiroyuki、Nii Yoshitaka、Burish Mark J.、Yagita Kazuhiro、Takahashi Akira、Yoo Seung‐Hee、Chen Zheng
- Journal Title
  
  Molecular Nutrition & Food Research
  
  Volume: 67 Issue: 9 Pages: 2200270-2200270
- DOI
  10.1002/mnfr.202200270
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0274, KAKENHI-PROJECT-19K06770, KAKENHI-PROJECT-22K18366
[Journal Article] Comprehensive Analysis Identified the Circadian Clock and Global Circadian Gene Expression in Human Corneal Endothelial Cells2022
- Author(s)
  Hiroko Nakai, Yoshiki Tsuchiya, Nobuya Koike, Taiki Asano, Morio Ueno, Yasuhiro Umemura, Yuh Sasawaki, Ryotaro Ono, Jyunji Hamuro, Chie Sotozono, Kazyhiro Yagita
- Journal Title
  
  Investigative Ophthalmology & Visual Science
  
  Volume: 63 Issue: 5 Pages: 1-11
- DOI
  10.1167/iovs.63.5.16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16863, KAKENHI-ORGANIZER-21H05129, KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-21H02664, KAKENHI-PROJECT-19K06770, KAKENHI-PROJECT-22K18366
[Journal Article] The clock modulator Nobiletin mitigates astrogliosis-associated neuroinflammation and disease hallmarks in an Altzheimer's disease model.2022
- Author(s)
  4.Wiroanto M, Wang C-Y, Kim E, Koike N, Gomez-Gutierrez R, Nohara K, Escobedo Jr G, Choi JM, Han C, Yagita K, Jung SY, Soto C, Lee HK, Morales R, Yoo S-H, Chen Z.
- Journal Title
  
  FASEB J.
  
  Volume: 36 Issue: 3
- DOI
  10.1096/fj.202101633r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22516, KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-21H02664, KAKENHI-PROJECT-19K06770
[Journal Article] Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids2021
- Author(s)
  Umemura Yasuhiro、Koike Nobuya、Tsuchiya Yoshiki、Watanabe Hitomi、Kondoh Gen、Kageyama Ryoichiro、Yagita Kazuhiro
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 1
- DOI
  10.1073/pnas.2114083119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06679, KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-21H02664, KAKENHI-PROJECT-19K06770, KAKENHI-ORGANIZER-21H05129
[Journal Article] Quantitative morphometric analysis of molar teeth and alveolar bone using micro-computed tomography in aged mice2021
- Author(s)
  Ono Ryutaro、Abe Makoto、Koike Nobuya、Inokawa Hitoshi、Tsuchiya Yoshiki、Umemura Yasuhiro、Sasawaki Yuh、Yamamoto Toshiro、Wakisaka Satoshi、Kanamura Narisato、Yagita Kazuhiro
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 63 Issue: 3 Pages: 265-270
- DOI
  10.1016/j.job.2021.07.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06770, KAKENHI-PROJECT-20K16863, KAKENHI-PROJECT-21K21092, KAKENHI-PROJECT-16H06276
[Journal Article] Natural antisense transcript of <i>Period2, Per2AS,</i> regulates the amplitude of the mouse circadian clock2021
- Author(s)
  Mosig Rebecca A.、Castaneda Allison N.、Deslauriers Jacob C.、Frazier Landon P.、He Kevin L.、Maghzian Naseem、Pokharel Aarati、Schrier Camille T.、Zhu Lily、Koike Nobuya、Tyson John J.、Green Carla B.、Takahashi Joseph S.、Kojima Shihoko
- Journal Title
  
  Genes & Development
  
  Volume: 35 Issue: 11-12 Pages: 899-913
- DOI
  10.1101/gad.343541.120
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06770
[Journal Article] Circadian regulation of chemotherapy-induced peripheral neuropathic pain and the underlying transcriptomic landscape2020
- Author(s)
  Kim Hee Kee、Lee Sun-Yeul、Koike Nobuya、Kim Eunju、Wirianto Marvin、Burish Mark J.、Yagita Kazuhiro、Lee Hyun Kyoung、Chen Zheng、Chung Jin Mo、Abdi Salahadin、Yoo Seung-Hee
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 13844-13844
- DOI
  10.1038/s41598-020-70757-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06770, KAKENHI-PROJECT-19K22516, KAKENHI-PROJECT-18H02600
[Journal Article] Robust circadian clock oscillation and osmotic rhythms in inner medulla reflecting cortico-medullary osmotic gradient rhythm in rodent kidney2017
- Author(s)
  Hara Masayuki、Minami Yoichi、Ohashi Munehiro、Tsuchiya Yoshiki、Kusaba Tetsuro、Tamagaki Keiichi、Koike Nobuya、Umemura Yasuhiro、Inokawa Hitoshi、Yagita Kazuhiro
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 2045-2322
- DOI
  10.1038/s41598-017-07767-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01880, KAKENHI-PROJECT-15H04683
[Journal Article] Involvement of posttranscriptional regulation ofClockin the emergence of circadian clock oscillation during mouse development2017
- Author(s)
  Umemura Yasuhiro、Koike Nobuya、Ohashi Munehiro、Tsuchiya Yoshiki、Meng Qing Jun、Minami Yoichi、Hara Masayuki、Hisatomi Moe、Yagita Kazuhiro
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 114 Issue: 36
- DOI
  10.1073/pnas.1703170114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01880, KAKENHI-PROJECT-16K19008, KAKENHI-PROJECT-15H04683
[Journal Article] Period23′-UTR and microRNA-24 regulate circadian rhythms by repressing PERIOD2 protein accumulation2017
- Author(s)
  Yoo Seung-Hee、Kojima Shihoko、Shimomura Kazuhiro、Koike Nobuya、Buhr Ethan D.、Furukawa Tadashi、Ko Caroline H.、Gloston Gabrielle、Ayoub Christopher、Nohara Kazunari、Reyes Bryan A.、Tsuchiya Yoshiki、Yoo Ook-Joon、Yagita Kazuhiro、Lee Choogon、Chen Zheng、Yamazaki Shin、Green Carla B.、Takahashi Joseph S.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 114 Issue: 42
- DOI
  10.1073/pnas.1706611114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01880, KAKENHI-PROJECT-15H04683
[Journal Article] Disruption of circadian clockwork in in vivo reprogramming-induced mouse kidney tumors2017
- Author(s)
  Ohashi Munehiro、Umemura Yasuhiro、Koike Nobuya、Tsuchiya Yoshiki、Inada Yutaka、Watanabe Hitomi、Tanaka Tomoko、Minami Yoichi、Ukimura Osamu、Miki Tsuneharu、Tajiri Tatsuro、Kondoh Gen、Yamada Yasuhiro、Yagita Kazuhiro
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 2 Pages: 60-69
- DOI
  10.1111/gtc.12552
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-16K19008, KAKENHI-PROJECT-16H01880, KAKENHI-PROJECT-15H04683
[Journal Article] The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome2016
- Author(s)
  Baokun He, Kazunari Nohara, Noheon Park, Yong-Sung Park, Bobby Guillory, Zhaoyang Zhao, Jose M. Garcia, Nobuya Koike, Cheng Chi Lee, Joseph S. Takahashi, Seung-Hee Yoo, Zheng Chen
- Journal Title
  
  Cell Metab
  
  Volume: 23 Issue: 4 Pages: 610-621
- DOI
  10.1016/j.cmet.2016.03.007
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293048
[Journal Article] Effect of Multiple clock gene ablations on the circadian period-length and temperature compensation in mammalian cells.2016
- Author(s)
  Tsuchiya Y., Umemura Y., Minami Y., Koike N., Hosokawa T., Hara M., Ito H., Inokawa H. & Yagita K.
- Journal Title
  
  Journal of Biological Rhythms
  
  Volume: 31 Issue: 1 Pages: 48-56
- DOI
  10.1177/0748730415613888
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08212, KAKENHI-PROJECT-26350697, KAKENHI-PROJECT-26650121, KAKENHI-PROJECT-16H01880, KAKENHI-PROJECT-15H04683
[Journal Article] Ammonia-lowering activities and carbamoyl phosphate synthetase 1 (Cps1) induction mechanism of a natural flavonoid2015
- Author(s)
  Kazunari Nohara, Youngmin Shin, Noheon Park, Kwon Jeong, Baokun He, Nobuya Koike, Seung-Hee Yoo, and Zheng Chen
- Journal Title
  
  Nutr Metab (Lond)
  
  Volume: 12 Issue: 1 Pages: 23-23
- DOI
  10.1186/s12986-015-0020-7
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293048
[Journal Article] Robust Circadian Rhythm and Parathyroid Hormone-Induced Resetting during Hypertrophic Differentiation in ATDC5 Chondroprogenitor Cells2015
- Author(s)
  Toshihiro Hosokawa, Yoshiki Tsuchiya, Naoki Okubo, Tatsuya Kunimoto, Yoichi Minami, Hiroyoshi Fujiwara, Yasuhiro Umemura, Nobuya Koike, Toshikazu Kubo, Kazuhiro Yagita
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 48 Issue: 6 Pages: 165-171
- DOI
  10.1267/ahc.15025
- NAID
  130005116781
- ISSN
  0044-5991, 1347-5800
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10453, KAKENHI-PROJECT-15K20012, KAKENHI-PROJECT-15H04683
[Journal Article] Dual attenuation of proteasomal and autophagic BMAL1 degradation in ClockΔ19/+ mice contributes to improved glucose homeostasis2015
- Author(s)
  Kwon Jeong, Baokun He, Kazunari Nohara, Noheon Park, Youngmin Shin, Seonghwa Kim, Kazuhiro Shimomura, Nobuya Koike, Seung-Hee Yoo, and Zheng Chen
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 12801-12801
- DOI
  10.1038/srep12801
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293048
[Patent] 被験者の概日リズムを提示するための提示装置、提示方法、及び提示プログラム2022
- Inventor(s)
  八木田和弘先生、小池宣也先生、笹脇ゆふ
- Industrial Property Rights Holder
  京都府公立大学法人
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-557592
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-19K06770
[Presentation] 長期間明暗シフト環境暴露に伴う腸内細菌叢の時系列変容プロセス2023
- Author(s)
  山﨑熙成、小池宣也、八木田和弘
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-19K06770
[Presentation] 慢性的概日リズム不適合による病態成立プロセス2023
- Author(s)
  小池宣也, 梅村康浩, 八木田和弘
- Organizer
  日本生理学会第100回記念大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06770
[Presentation] 明暗シフト環境暴露に伴う腸内細菌叢の変容プロセス2022
- Author(s)
  山﨑熙成、小池宣也、八木田和弘
- Organizer
  第114回近畿生理学談話会
- Data Source
  KAKENHI-PROJECT-19K06770
[Presentation] 明暗シフト環境暴露に伴う腸内細菌叢の変容プロセス2022
- Author(s)
  山﨑熙成、小池宣也、八木田和弘
- Organizer
  第12回４大学連携研究フォーラム
- Data Source
  KAKENHI-PROJECT-19K06770
[Presentation] Systematic phenotyping in presymptomatic state of circadian rhythm disorders2021
- Author(s)
  小池宣也, 梅村康浩, 井之川仁, 笹脇ゆふ, 土谷佳樹, 八木田和弘
- Organizer
  第28回日本時間生物学会学術大会
- Data Source
  KAKENHI-PROJECT-19K06770
[Presentation] , 階層を超えた包括的フェノタイプ解析による概日リズム障害成立プロセスの解明2021
- Author(s)
  小池宣也, 梅村康浩, 井之川仁, 笹脇ゆふ, 土谷佳樹, 八木田和弘
- Organizer
  第113 回近畿生理学談話会
- Data Source
  KAKENHI-PROJECT-19K06770
[Presentation] Chromatin accessibility dynamics across in vitro cellular differentiation2019
- Author(s)
  小池宣也、梅村康浩、八木田和弘
- Organizer
  第26回日本時間生物学会学術大会
- Data Source
  KAKENHI-PROJECT-19K06770
[Presentation] 概日転写サイクルとクロマチンランドスケープ2015
- Author(s)
  小池宣也
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-26293048

1. YAGITA Kazuhiro (90324920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. Chen Zheng

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. UMEMURA Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. UEBANSO Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 高橋章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 馬渡一諭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 下畑隆明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 笹脇ゆふ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 渡邊仁美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 土谷佳樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOIKE NOBUYA 小池 宣也

Koike Nobuya 小池 宣也

Research Projects

Research Products

Co-Researchers

Analysis of pre-symptomatic pathophysiology in chronic jet-lag mouse modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epigenetic analysis for emergence of mammalian circadian rhythmsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Developmental mechanisms of circadian clock in mouse embryo

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Circadian transcriptome analysis for protection against obesity developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Circadian Features of Cluster Headache and Migraine: A Systematic Review, Meta-analysis, and Genetic Analysis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Polymethoxyflavone Sudachitin Modulates the Circadian Clock and Improves Liver Physiology2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive Analysis Identified the Circadian Clock and Global Circadian Gene Expression in Human Corneal Endothelial Cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The clock modulator Nobiletin mitigates astrogliosis-associated neuroinflammation and disease hallmarks in an Altzheimer's disease model.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quantitative morphometric analysis of molar teeth and alveolar bone using micro-computed tomography in aged mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Natural antisense transcript of <i>Period2, Per2AS,</i> regulates the amplitude of the mouse circadian clock2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Circadian regulation of chemotherapy-induced peripheral neuropathic pain and the underlying transcriptomic landscape2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Robust circadian clock oscillation and osmotic rhythms in inner medulla reflecting cortico-medullary osmotic gradient rhythm in rodent kidney2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of posttranscriptional regulation ofClockin the emergence of circadian clock oscillation during mouse development2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Period23′-UTR and microRNA-24 regulate circadian rhythms by repressing PERIOD2 protein accumulation2017

KOIKE NOBUYA 小池宣也

Koike Nobuya 小池宣也