Metoki Tomomi 目時友美

… Alternative Names

METOKI Tomomi 目時友美

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Researcher Number	00400169
Affiliation (based on the past Project Information) *help	2021: 弘前大学, 医学研究科, 客員研究員 2020: 弘前大学, 大学院医学研究科, 客員研究員 2017 – 2019: 弘前大学, 医学部附属病院, 講師 2013 – 2015: 弘前大学, 医学部附属病院, 講師 2010 – 2011: Hirosaki University, 医学部附属病院, 講師 2009: Hirosaki University, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Ophthalmology
Keywords	Principal Investigator 眼科学 / カルパイン / 網膜色素変性 / 緑内障手術 / 薬理学 / 緑内障濾過手術 / 線維芽細胞 / 線維柱帯切除手術 / 眼圧 / 濾過胞 … More / トレハロース / 線維柱帯切除術 / 緑内障 / ウサギ / ペプチド療法 / 視細胞保護 / iPS細胞 / ミトコンドリアカルパイン / 眼薬理学 / RCSラット / アポトーシス誘導因子 / 細胞質 / ミトコンドリア / アポトーシス / 視細胞 Less

Basic and Clinical Researches regarding the effect of trehakose eyedrops on maintaining postoperative filtration blrbPrincipal Investigator
- Principal Investigator
  
  Metoki Tomomi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Hirosaki University
Strategy of photoreceptor protective treatment for retinitis pigmentosaPrincipal Investigator
- Principal Investigator
  
  Metoki Tomomi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Hirosaki University
トレハロース点眼ヒアルロン酸膜併用による濾過胞維持の新規治療法の開発Principal Investigator
- Principal Investigator
  
  目時友美
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Hirosaki University
EFFECT OF CALPAINS ON PHOTORECEPTOR DEGENERATION AND POSSIBILITY OF NEW TREATMENT FOR PHOTORECEPTOR PROTECTIONPrincipal Investigator
- Principal Investigator
  
  METOKI Tomomi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Hirosaki University

All 2019 2018 2017 2014 2013 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] 強膜炎（分担執筆）　実戦メディカル眼科治療アップデート2019
- Author(s)
  目時友美
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-17K11416
[Journal Article] N-methyl-N-nitrosourea-induced photoreceptor degeneration is inhibited by nicotinamide via the blockade of upstream events before the phosphorylation of signaling proteins.2019
- Author(s)
  Sugano E, Tabata K, Takezawa T, Shiraiwa R, Muraoka H, Metoki T, Kudo A, Nakazawa M, Tomita H, Iwama Y
- Journal Title
  
  BioMed Research International
  
  Volume: 2019 Pages: 1-10
- DOI
  10.1155/2019/3238719
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11416, KAKENHI-PROJECT-18K09433, KAKENHI-PROJECT-19K09926, KAKENHI-PLANNED-17H06330, KAKENHI-PROJECT-19H03807, KAKENHI-PROJECT-19K09945
[Journal Article] ぶどう膜炎にてステロイド治療中にニューモシスチス肺炎を併発した死亡例1例を含む3症例2018
- Author(s)
  工藤孝志、江目孝幸、田名部玲子、工藤朝香、目時友美、安達功武、鈴木幸彦、中澤　満
- Journal Title
  
  臨床眼科
  
  Volume: 72 Pages: 775-780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11416
[Journal Article] Macular edema associated with intraocular ointment after cataract surgery2018
- Author(s)
  Kudo A, Kudo T, Takahashi D, Metoki T, Suzuki Y, Nakazawa M
- Journal Title
  
  American Journal of Ophthalmology Case Reports
  
  Volume: 10 Pages: 152-156
- DOI
  10.1016/j.ajoc.2018.02.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11313, KAKENHI-PROJECT-17K11416, KAKENHI-PROJECT-15K20245
[Journal Article] A case of childfood vitrectomy to a dense vitreous hemorrhage secondary to leukemia therapy and tumor lysis syndrome2014
- Author(s)
  Kudo T, Suzuki Y, Metoki T, Nakazawa M
- Journal Title
  
  Case Reports in Ophthalmology
  
  Volume: 6 Issue: 1 Pages: 2015-2015
- DOI
  10.1159/000374088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592616, KAKENHI-PROJECT-25462746, KAKENHI-PROJECT-15K20245
[Journal Article] Effects of intravitreal injection of bevacizumab on inflammatory cytokines in the vitreaous with proliferative diabetic retinopathy.2014
- Author(s)
  Suzuki Y, Suzuki K, Yokoi Y, Miyagawa Y, Metoki T, Nakazawa M.
- Journal Title
  
  Retina
  
  Volume: 34 Pages: 51-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462746
[Journal Article] Long-term effects of nilvadipine against progression of the central visual field defect in retinitis pigmentosa: An extended study.2013
- Author(s)
  Nakazawa M, Suzuki Y, Ito T, Metoki T, Kudo T, Ohguro H.
- Journal Title
  
  BioMed Research International
  
  Volume: 2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462746
[Journal Article] Effect of nilvadipine on central visual field in retinitis pigmentosa : a 30-month clinical trial.2011
- Author(s)
  Nakazawa M, Ohguro H, Takeuchi K, Miyagawa Y, Ito T, Metoki T
- Journal Title
  
  Ophthalmologica
  
  Volume: 225 Pages: 120-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] Effect of nilvadipine on central visual field in retinitis pigmentosa : a 30-month clinical trial.2011
- Author(s)
  Nakazawa M, Ohguro H, Takeuchi K, Miyagawa Y, Ito T, Metoki T.
- Journal Title
  
  Ophthalmologica 225(1)
  
  Pages: 120-126
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] Effects of Solid Hyaluronic Acid Film on Postoperative Fibrous Scar Formation after Strabismus Surgery in Animals2010
- Author(s)
  Takeuchi K, Nakazawa M, Metoki T, Yamazaki H, Miyagawa Y, Ito T
- Journal Title
  
  J Pediat Ophth Strab.
  
  Volume: (印刷中 (web上で公開))
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] Activation of mitochondrial calpain and release of apoptosis-inducing factor from mitochondria in RCS rat retinal degeneration.2010
- Author(s)
  Mizukoshi S, Nakazawa M, Sato K, Ozaki T, Metoki T, Ishiguro S.
- Journal Title
  
  Exp Eye Res. 91
  
  Pages: 353-361
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] トラボプロスト点眼液の点状表層角膜症に対する影響2010
- Author(s)
  山崎仁志、宮川靖博、目時友美、鈴木香、伊藤忠、横井由美子、木村智美、中澤満
- Journal Title
  
  あたらしい眼科 27(8)
  
  Pages: 1123-1126
- NAID
  10027747814
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] Activation of mitochondrial calpain and release of apoptosis-inducing factor from mitochondria in RCS rat retinal degeneration.2010
- Author(s)
  Mizukoshi S, Nakazawa M, Sato K, Ozaki T, Metoki T, Ishiguro S
- Journal Title
  
  Experimental Eye Research
  
  Volume: 91 Pages: 353-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] Morphological findings of intraocular lens with haptics detached from optics following cataract surgery.2010
- Author(s)
  Suzuki Y, Suzuki K, Metoki T, Nakazawa M.
- Journal Title
  
  Ophthalmic Surgery, Lasers & Imaging in press.
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] Effects of Solid Hyaluronic Acid Film on Postoperative Fibrous Scar Formation after Strabismus Surgery in Animals2010
- Author(s)
  Takeuchi K, Nakazawa M, Metoki T, Yamazaki H, Miyagawa Y, Ito T.
- Journal Title
  
  J Pediat Ophth Strab. In press.
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] 内境界膜自然剥離を伴った黄斑円孔症例2009
- Author(s)
  伊藤忠、山崎仁志、横井由美子、目時友美、竹内侯雄、木村智美、中澤満、楠美智己
- Journal Title
  
  あたらしい眼科 26(12)
  
  Pages: 1693-1696
- NAID
  10026923740
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] 各種緑内障手術の成績2009
- Author(s)
  木村智美、石川太、山崎仁志、目時友美、伊藤忠、竹内侯雄、中澤満
- Journal Title
  
  あたらしい眼科 26(9)
  
  Pages: 1279-1285
- NAID
  10026256368
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] 内境界膜自然剥離を伴った黄斑円孔症例2009
- Author(s)
  伊藤忠、目時友美, 他
- Journal Title
  
  あたらしい眼科 26
  
  Pages: 1693-1696
- NAID
  10026923740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] Solid hyaluronic acid prevents postoperative fibrous scar formation in experimental animal eyes.2009
- Author(s)
  Takeuchi K, Nakazawa M, Yamazaki H, Miyagawa Y, Ito T, Ishikawa F, Metoki T.
- Journal Title
  
  Arch Ophthalmol 127(4)
  
  Pages: 460-464
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] 各種緑内障手術の成績2009
- Author(s)
  木村智美、目時友美, 他
- Journal Title
  
  あたらしい眼科 26
  
  Pages: 1279-1285
- NAID
  10026256368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791662
[Journal Article] Solid hyaluronic acid prevents postoperative fibrous scar formation in experimental animal eyes2009
- Author(s)
  Takeuchi K, Metoki T, et al.
- Journal Title
  
  Archives of Ophthalmology 127
  
  Pages: 460-464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791662
[Presentation] 内境界膜剥離操作が神経節細胞層に及ぼす影響2018
- Author(s)
  工藤孝志、鈴木幸彦、目時友美、安達功武、毛内奈津姫、中澤　満
- Organizer
  第122回日本眼科学会
- Data Source
  KAKENHI-PROJECT-17K11416
[Presentation] 術前網膜光凝固の有無による糖尿病網膜症の硝子体サイトカインと術後炎症2018
- Author(s)
  鈴木幸彦、安達功武、工藤孝志、鈴木　香、目時友美、中澤　満
- Organizer
  第122回日本眼科学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11416
[Presentation] 増殖糖尿病網膜症に対する汎網膜光凝固術既往の有無による硝子体サイトカイン濃度の差2017
- Author(s)
  鈴木幸彦、安達功武、工藤孝志、鈴木　香、目時友美、中澤　満
- Organizer
  第121回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-17K11416
[Presentation] 肥厚性硬膜炎と眼窩先端症候群を呈した症例2011
- Author(s)
  目時友美、鈴木幸彦、木村智美、盛泰子、横井由美子、竹内侯雄、鈴木香、伊藤忠、宮川靖博、中澤満、野田康子
- Organizer
  第115回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2011-05-11
- Data Source
  KAKENHI-PROJECT-21791662
[Presentation] 眼内悪性リンパ腫を契機に発見されたT細胞リンパ腫の1例2010
- Author(s)
  横井由美子、山崎仁志、目時友美、鈴木幸彦、木村智美、鈴木香、伊藤忠、中澤満、高畑武功、和田龍一、杉田直
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2010-04-15
- Data Source
  KAKENHI-PROJECT-21791662
[Presentation] ニルバジピンの網膜色素変性の中心視野進行への影響2010
- Author(s)
  中澤満、大黒浩、山崎仁志、目時友美、宮川靖博、伊藤忠、竹内侯雄、横井由美子
- Organizer
  第64回日本臨床眼科学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-21791662
[Presentation] ニルバジピンの網膜色素変性の中心視野進行への影響2010
- Author(s)
  中澤満、目時友美, (ほか)
- Organizer
  第64回日本臨床眼科学会総会
- Place of Presentation
  神戸国際会議場(神戸市)
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-21791662
[Presentation] 両眼の再発性視神経炎を初発症状とした抗好中球細胞質抗体関連腎炎2010
- Author(s)
  鈴木香、鈴木幸彦、伊藤忠、目時友美、中澤満
- Organizer
  第114回日本眼科学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2010-04-15
- Data Source
  KAKENHI-PROJECT-21791662
[Presentation] RCSラット網膜変性に対するミトコンドリアカルパインの関与とその制御の時間効果2009
- Author(s)
  中澤満、目時友美, 他
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京都
- Year and Date
  2009-04-16
- Data Source
  KAKENHI-PROJECT-21791662
[Presentation] トレハロースによる結膜および皮膚線維芽細胞の抑制効果について2009
- Author(s)
  竹内侯雄、蝦名祐一、山崎仁志、宮川靖博、伊藤忠、目時友美、横井由美子、中澤満
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2009-04-16
- Data Source
  KAKENHI-PROJECT-21791662
[Presentation] ニルバジピンの網膜色素変性に対する進行遅延効果2009
- Author(s)
  中澤満、大黒浩、山崎仁志、目時友美、宮川靖博、伊藤忠、竹内侯雄、横井由美子
- Organizer
  第63回日本臨床眼科学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21791662
[Presentation] ミトコンドリア・カルパイン－１阻害デコイペプチド点眼のウサギ網膜への送達
- Author(s)
  中澤　満、尾﨑　拓、目時友美、安達功武、髙橋　静、石黒誠一、山下哲郎
- Organizer
  第34回日本眼薬理学会
- Place of Presentation
  長良川国際会議場
- Year and Date
  2014-09-13 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-25462746

1. Nakazawa Mitsuru (80180272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

Metoki Tomomi 目時 友美

METOKI Tomomi 目時 友美

Research Projects

Research Products

Co-Researchers

Basic and Clinical Researches regarding the effect of trehakose eyedrops on maintaining postoperative filtration blrbPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Strategy of photoreceptor protective treatment for retinitis pigmentosaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

トレハロース点眼ヒアルロン酸膜併用による濾過胞維持の新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EFFECT OF CALPAINS ON PHOTORECEPTOR DEGENERATION AND POSSIBILITY OF NEW TREATMENT FOR PHOTORECEPTOR PROTECTIONPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 強膜炎（分担執筆） 実戦メディカル眼科治療アップデート2019

Author(s)

Publisher

Data Source

[Journal Article] N-methyl-N-nitrosourea-induced photoreceptor degeneration is inhibited by nicotinamide via the blockade of upstream events before the phosphorylation of signaling proteins.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ぶどう膜炎にてステロイド治療中にニューモシスチス肺炎を併発した死亡例1例を含む3症例2018

Author(s)

Journal Title

Data Source

[Journal Article] Macular edema associated with intraocular ointment after cataract surgery2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A case of childfood vitrectomy to a dense vitreous hemorrhage secondary to leukemia therapy and tumor lysis syndrome2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of intravitreal injection of bevacizumab on inflammatory cytokines in the vitreaous with proliferative diabetic retinopathy.2014

Author(s)

Journal Title

Data Source

[Journal Article] Long-term effects of nilvadipine against progression of the central visual field defect in retinitis pigmentosa: An extended study.2013

Author(s)

Journal Title

Data Source

[Journal Article] Effect of nilvadipine on central visual field in retinitis pigmentosa : a 30-month clinical trial.2011

Author(s)

Journal Title

Data Source

[Journal Article] Effect of nilvadipine on central visual field in retinitis pigmentosa : a 30-month clinical trial.2011

Author(s)

Journal Title

Data Source

[Journal Article] Effects of Solid Hyaluronic Acid Film on Postoperative Fibrous Scar Formation after Strabismus Surgery in Animals2010

Author(s)

Journal Title

Data Source

[Journal Article] Activation of mitochondrial calpain and release of apoptosis-inducing factor from mitochondria in RCS rat retinal degeneration.2010

Author(s)

Journal Title

Data Source

[Journal Article] トラボプロスト点眼液の点状表層角膜症に対する影響2010

Author(s)

Journal Title

NAID

Metoki Tomomi 目時友美

METOKI Tomomi 目時友美

[Book] 強膜炎（分担執筆）　実戦メディカル眼科治療アップデート2019