Kitajima Masayuki 北島雅之

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KITAJIMA MASAYUKI 北島雅之

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Researcher Number	00401000
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立国際医療研究所肝炎・免疫研究センター, 上級研究員
Affiliation (based on the past Project Information) *help	2016 – 2023: 国立研究開発法人国立国際医療研究センター, その他部局等, 上級研究員 2015: 国立研究開発法人国立国際医療研究センター, その他部局等, その他
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Experimental pathology / Dermatology
Keywords	Principal Investigator アレルギー性皮膚炎 / TSLP / Themis / T細胞 / 物理的刺激 / 化学的刺激 / IL-33 / 炎症増悪化 / CD4 / IL-4 / Th2 / 慢性炎症

アレルギー性皮膚炎におけるT細胞特異的分子Themisの役割の解明Principal Investigator
- Principal Investigator
  
  北島雅之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  National Center for Global Health and Medicine
Analysis of exacerbation of allergic skin inflammationPrincipal Investigator
- Principal Investigator
  
  Kitajima Masayuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  National Center for Global Health and Medicine
Exacerbation mechanism of allergic skin inflammationPrincipal Investigator
- Principal Investigator
  
  KITAJIMA MASAYUKI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Center for Global Health and Medicine
Role of TSLP in skin inflammation at chronic stagePrincipal Investigator
- Principal Investigator
  
  KITAJIMA MASAYUKI
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  National Center for Global Health and Medicine

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Epithelial cell-derived cytokine TSLP modulates metabolic program of regulatory T cells by enhancing fatty acid uptake to suppress the intestinal inflammation2023
- Author(s)
  Kasuya T., Tanaka S., Etori K., Shoda J., Hattori K., Endo Y., Kitajima M., Kageyama T., Iwamoto T., Yokota M., Iwata A., Suto A., Suzuki K., Suzuki H., Ziegler SF., and Nakajima H
- Journal Title
  
  Sci. Rep.
  
  Volume: 13 Issue: 1 Pages: 1653-1653
- DOI
  10.1038/s41598-023-28987-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-20K07460, KAKENHI-PROJECT-20K08797, KAKENHI-PROJECT-21K16297, KAKENHI-PROJECT-23K06590, KAKENHI-PROJECT-23K07738, KAKENHI-PROJECT-22K16353
[Journal Article] Critical Role of TSLP Receptor on CD4 T Cells for Exacerbation of Skin Inflammation2020
- Author(s)
  Kitajima Masayuki、Kubo Masato、Ziegler Steven F.、Suzuki Harumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: - Issue: 1 Pages: 27-35
- DOI
  10.4049/jimmunol.1900758
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08803, KAKENHI-PROJECT-20K07460, KAKENHI-PROJECT-19H03491
[Journal Article] The role of Nqo1 in contact hyper-sensitivity2019
- Author(s)
  Kitajima Masayuki, Suzuki Harumi
- Journal Title
  
  Clinical immunology & allergology
  
  Volume: 72 Pages: 1-6
- NAID
  40021959344
- Data Source
  KAKENHI-PROJECT-17K08803
[Journal Article] Cutting Edge: Nqo1 Regulates Irritant Contact Hypersensitivity against Croton Oil through Maintenance of Dendritic Epidermal T Cells2018
- Author(s)
  Kitajima Masayuki、Kimura Akihiro、Suzuki Harumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 200 Issue: 5 Pages: 1555-1559
- DOI
  10.4049/jimmunol.1701389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08803, KAKENHI-PROJECT-17K08896
[Journal Article] Rasal3-mediated T cell survival is essential for inflammatory responses2018
- Author(s)
  Muro Ryunosuke、Nitta Takeshi、Kitajima Masayuki、Okada Toshiyuki、Suzuki Harumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 496 Issue: 1 Pages: 25-30
- DOI
  10.1016/j.bbrc.2017.12.159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08803, KAKENHI-PROJECT-16K19102, KAKENHI-PROJECT-16K19375, KAKENHI-PROJECT-16H05202, KAKENHI-PROJECT-15H05703
[Journal Article] NQO1 inhibits the TLR-dependent production of selective cytokines by promoting IκB-ζ degradation.2018
- Author(s)
  1. Kimura, A., Kitajima, M., Nishida, K., Serada, S., Fujimoto, M., Naka, T., Fuji-Kuriyama, Y., Ito, T., Handa, H., Tanaka, T, Yoshimura, A., Suzuki, H.
- Journal Title
  
  Journal of experimental medicine
  
  Volume: 215 Issue: 8 Pages: 2197-2200
- DOI
  10.1084/jem.20172024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08803, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-17H04213, KAKENHI-PROJECT-17K08896
[Journal Article] Baculovirus directly activates murine NK cells via TLR92017
- Author(s)
  Moriyama, T., Suzuki, T., Chang, Mo., Kitajima, M., Takaku, H.
- Journal Title
  
  The Journal of Cancer Gene and Cellular Therapies
  
  Volume: - Issue: 4 Pages: 175-179
- DOI
  10.1038/cgt.2017.2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21649, KAKENHI-PROJECT-17K08803
[Journal Article] A Histone Methyltransferase ESET Is Critical for T Cell Development2016
- Author(s)
  Takikita, S. Muro, R. Takai, T. Otsubo, T. Kawamura, Y. I. Dohi, T. Oda, H. Kitajima, M. Oshima, K. Hattori, M. Endo, T. A. Toyoda, T. Weis, J. Shinkai, Y. Suzuki, H.
- Journal Title
  
  J Immunol
  
  Volume: 197 Issue: 6 Pages: 2269-2279
- DOI
  10.4049/jimmunol.1502486
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04503, KAKENHI-PROJECT-15K21649, KAKENHI-PROJECT-16K19102
[Journal Article] Baculovirus infection of human monocyte-derived dendritic cells restricts HIV-1 replication.2015
- Author(s)
  Oo Chang, M., Suzuki, T., Kitajima, M., Takaku, H.
- Journal Title
  
  AID Res Hum Retrovirues
  
  Volume: 10 Issue: 10 Pages: 1023-1031
- DOI
  10.1089/aid.2015.0060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21649
[Presentation] Themis regulates CD8-dependent contact hypersensitivity.2024
- Author(s)
  M Kitajima, T Okada, H Suzuki
- Organizer
  The 52th Annual meeting of the Japanese society for Immunology
- Data Source
  KAKENHI-PROJECT-23K06513
[Presentation] Themis in peripheral CD8 T cells regulates hapten-induced allergic skin inflammation.2022
- Author(s)
  M Kitajima, T Okada, H Suzuki
- Organizer
  The 51th Annual meeting of the Japanese society for Immunology
- Data Source
  KAKENHI-PROJECT-20K07460
[Presentation] Low dose of hapten-induced allergic skin inflammation is aggravated in Themis overexpressing mice.2021
- Author(s)
  M Kitajima, T Okada, H Suzuki
- Organizer
  The 50th Annual meeting of the Japanese society for Immunology
- Data Source
  KAKENHI-PROJECT-20K07460
[Presentation] Significant role of TSLP receptor on CD4 T cells in chronic skin inflammation.2019
- Author(s)
  M Kitajima, SF Ziegler, H Suzuki
- Organizer
  The 17th International Congress of Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08803
[Presentation] Critical role of TSLPR on CD4 T cells for exacerbation of type 2 skin inflammation.2019
- Author(s)
  M Kitajima, SF Ziegler, H Suzuki
- Organizer
  The 29th Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-17K08803
[Presentation] Critical role of TSLP receptor on CD4 T cells for exacerbation of Th2-type skin inflammaion.2019
- Author(s)
  M Kitajima, SF Ziegler, H Suzuki
- Organizer
  The 48th Annual meeting of the Japanese society for Immunology
- Data Source
  KAKENHI-PROJECT-17K08803
[Presentation] Critical role of TSLP receptor on CD4 T cells for exacerbation of skin inflammation.2019
- Author(s)
  M Kitajima, SF Ziegler, H Suzuki
- Organizer
  ThymE: T cell and thymus biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08803
[Presentation] The Pathogenesis of TSLP-responded Th2 cells in exacerbation of skin inflammation.2018
- Author(s)
  M Kitajima, SF Ziegler, H Suzuki
- Organizer
  The 47th Annual meeting of the Japanese society for Immunology, Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-17K08803
[Presentation] The novel ubiquitin ligase complex, NQO1-PDLIM2 inhibits TLR-dependent production of selective cytokines by degrading.2017
- Author(s)
  A Kimura, M Kitajima, H Suzuki
- Organizer
  The Cytokines
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08803
[Presentation] Role of TSLPR on CD4 T cells in exacerbation of skin inflammation.2017
- Author(s)
  M Kitajima, SF Ziegler, H Suzuki
- Organizer
  The 46th Annual meeting of the Japanese society for Immunology
- Data Source
  KAKENHI-PROJECT-17K08803
[Presentation] The novel ubiquitin ligase complex, NQO1-PDLIM2 inhibits TLR-dependent production of selective cytokines by degrading IκB-ζ.2017
- Author(s)
  A Kimura, M Kitajima, H Suzuki
- Organizer
  The 46th Annual meeting of the Japanese society for Immunology
- Data Source
  KAKENHI-PROJECT-17K08803
[Presentation] NAD(P)H:quinone oxidoreductase (Nqo1) regulates irritant contact dermatitis through homeostasis of epidermal γδ T cells.2016
- Author(s)
  M Kitajima, A Kimura, H Suzuki
- Organizer
  第４５回　日本免疫学会総会・学術集会
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K21649
[Presentation] NAD(P)H:quinone oxidoreductase (Nqo1) regulates irritant contact dermatitis through homeostasis of epidermal γδ T cells.2016
- Author(s)
  M Kitajima, A Kimura, H Suzuki
- Organizer
  Immunology 2016, The American Association of Immunologists Annual meeting
- Place of Presentation
  Seattle
- Year and Date
  2016-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21649
[Presentation] NAD(P)H:quinone oxidoreductase (Nqo1) regulates irritant contact dermatitis2015
- Author(s)
  Masayuki Kitajima, Akihiro Kimura, Harumi Suzuki
- Organizer
  第４４回　日本免疫学会学術集会
- Place of Presentation
  札幌市
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-15K21649

1. KAWAMURA Yuki I

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# of Collaborated Products: 1 results
2. 土肥多恵子

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# of Collaborated Products: 1 results
3. 遠藤裕介

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# of Collaborated Products: 1 results

Kitajima Masayuki 北島 雅之

KITAJIMA MASAYUKI 北島 雅之

Research Projects

Research Products

Co-Researchers

アレルギー性皮膚炎におけるT細胞特異的分子Themisの役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of exacerbation of allergic skin inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exacerbation mechanism of allergic skin inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of TSLP in skin inflammation at chronic stagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Epithelial cell-derived cytokine TSLP modulates metabolic program of regulatory T cells by enhancing fatty acid uptake to suppress the intestinal inflammation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Critical Role of TSLP Receptor on CD4 T Cells for Exacerbation of Skin Inflammation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The role of Nqo1 in contact hyper-sensitivity2019

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Cutting Edge: Nqo1 Regulates Irritant Contact Hypersensitivity against Croton Oil through Maintenance of Dendritic Epidermal T Cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rasal3-mediated T cell survival is essential for inflammatory responses2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] NQO1 inhibits the TLR-dependent production of selective cytokines by promoting IκB-ζ degradation.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Baculovirus directly activates murine NK cells via TLR92017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Histone Methyltransferase ESET Is Critical for T Cell Development2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Baculovirus infection of human monocyte-derived dendritic cells restricts HIV-1 replication.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Themis regulates CD8-dependent contact hypersensitivity.2024

Author(s)

Organizer

Data Source

[Presentation] Themis in peripheral CD8 T cells regulates hapten-induced allergic skin inflammation.2022

Author(s)

Kitajima Masayuki 北島雅之

KITAJIMA MASAYUKI 北島雅之