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Takeuchi Emiko  竹内 恵美子

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TAKEUCHI Emiko  竹内 恵美子

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Researcher Number 00406935
Affiliation (Current) 2025: 北里大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2013 – 2021: 北里大学, 医学部, 講師
2009 – 2012: Kitasato University, 医学部, 助教
Review Section/Research Field
Principal Investigator
膠原病・アレルギー・感染症内科学 / Collagenous pathology/Allergology
Except Principal Investigator
Basic Section 53040:Nephrology-related / Collagenous pathology/Allergology
Keywords
Principal Investigator
好中球 / 骨髄混合キメラ / 骨髄移植 / プログラム細胞死 / 全身性エリテマトーデス / 好中球NETosis / ミトコンドリア / Apoptosis / NETosis / 慢性肉芽腫症 … More / 制御性細胞死 / SLE / 濾胞樹状細胞 / 全身性ループスエリテマトーデス / 自己反応性細胞 / アポトーシス / Fas/FasL / MHC拘束 / 臨床免疫学 … More
Except Principal Investigator
プログラム細胞死 / NETosis / 好中球 / 間質性腎炎 / 機能特異的マクロファージ / 線維化 / ネトーシス / 組織特異的マクロファージ / マクロファージ / Apoptosis / 慢性肉芽腫症 / 制御性細胞死 / 活性酸素 / 自己抗原提示 / NADPH酵素複合体 / 好中球Netosis / siRNA / p40phox / 好中球活性酸素 / 全身性エリテマトーデス Less
  • Research Projects

    (5 results)
  • Research Products

    (46 results)
  • Co-Researchers

    (4 People)
  •  The unbalance between post-inflammatory apoptosis and NETosis possibly effects on the phagocyte which accelerate interstitial fibrosis in kidney

    • Principal Investigator
      Takeuchi Yasuo
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Kitasato University
  •  NETs including oxidative mitochondria DNA might make worse the autoimmune-inflammation in CGDPrincipal Investigator

    • Principal Investigator
      Takeuchi Emiko
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Kitasato University
  •  The possibility that suppression of NETosis contributes to improvement of SLE

    • Principal Investigator
      Takeuchi Yasuo
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Kitasato University
  •  The induction of allogenic bone marrow chimerism regulates some lineage of auto-reactive lymphocite, but not all of them in lupus prone mice.Principal Investigator

    • Principal Investigator
      Takeuchi Emiko
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kitasato University
  •  T cells derived from donor bone marrow cells selectively regulate auto-reactive B cells in bone marrow mixed chimeric micePrincipal Investigator

    • Principal Investigator
      TAKEUCHI Emiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kitasato University

All 2021 2020 2019 2018 2017 2016 2015 2014 2012 2011 2010 2009 Other

All Journal Article Presentation Book

  • [Book] An Update Glomerulopathies2011

    • Author(s)
      Takeuchi E
    • Publisher
      INTECK
    • Data Source
      KAKENHI-PROJECT-21790950
  • [Journal Article] Inhibitory function of NKT cells during early induction phase of nickel allergy.2016

    • Author(s)
      Hironori Okuno, Masashi Satoh, Emiko Takeuchi, Koji Eshima, Masazumi Terashima, Jun Komotori, Sonoko Habu, Hidekazu Tamauchi, Kazuya Iwabuchi.
    • Journal Title

      Immunobiology

      Volume: in press Issue: 7 Pages: 833-838

    • DOI

      10.1016/j.imbio.2016.01.012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591469, KAKENHI-PROJECT-25460502, KAKENHI-PROJECT-25870708, KAKENHI-PROJECT-26430120, KAKENHI-PROJECT-16K21347
  • [Journal Article] A possible clue for the production of anti-glomerular basement membrane antibody associated with ureteral obstruction and hydronephritis.2015

    • Author(s)
      Takeuchi Y, Takeuchi E, Kamata K.
    • Journal Title

      Case Rep Nephrol Dial

      Volume: 5 Issue: 1 Pages: 87-95

    • DOI

      10.1159/000381396

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Journal Article] Curative haploidentical BMT in a murine model of X-linked chronic granulomatous disease.2015

    • Author(s)
      Takeuchi Y, Takeuchi E, Ishida T, Onodera M, Nakauchi H, Ohtsu M.
    • Journal Title

      Int J Hematol

      Volume: 102(1) Issue: 1 Pages: 111-120

    • DOI

      10.1007/s12185-015-1799-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591469, KAKENHI-PROJECT-15K15402
  • [Journal Article] 主要組織適合抗原不一致ドナーからの臍帯血移植による慢性肉芽腫症モデルマウスの治療2015

    • Author(s)
      田村昌也、竹内恵美子.
    • Journal Title

      北里医学

      Volume: 45(1) Pages: 53-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Journal Article] Covenient Evaluation of Magnitude of Glomerulonephritis in BXSB/Mp Lupus Mice.2014

    • Author(s)
      Takeuchi E, Iizuka M, Tamura M, Takeuchi Y.
    • Journal Title

      J Clin Cell Immunol

      Volume: 5 Issue: 02 Pages: 209-209

    • DOI

      10.4172/2155-9899.1000209

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Journal Article] Dysfunction of selective suppression of auto-antibody production in SLE mouse and reconstruction of this mechanism by induction of bone-marrow chimerism2012

    • Author(s)
      Emiko TAKEUCHI, Yasuo TAKEUCHI
    • Journal Title

      Journal of Transplantation Technology and Research

      Volume: IN THE PRESS

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Journal Article] Dysfunction of selective suppression of auto-antibody production in SLE mouse and reconstruction of this mechanism by induction of bone-marrow chimerism2012

    • Author(s)
      Takeuchi E, Takeuchi Y
    • Journal Title

      J of Transplantation Technology and Research

      Volume: (in the press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790950
  • [Journal Article] Dysfunction of selective suppression of auto-antibody production in SLE mouse and reconstruction of this mechanism by induction of bone marrow chimerism2012

    • Author(s)
      Takeuchi E, Takeuchi Y
    • Journal Title

      J of Transplantation Technologies & Research special issue

      Volume: 5(In press)

    • Data Source
      KAKENHI-PROJECT-21790950
  • [Journal Article] Allogenic mixed chimerism prevented autoimmune thrombocytopenia in BXSB lupus mice receiving donor BMT with nonlyniphoablative conditioning of low-dose TBI and anti CD40L mAb2011

    • Author(s)
      Takeuchi E
    • Journal Title

      Kitasato Med.J.

      Volume: 41(1) Pages: 50-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790950
  • [Journal Article] Cognate interaction plays a key role in the surveillance of autoreactive B cells in induced mixed bone marrow chimerism in BXSB lupus mice.2011

    • Author(s)
      Takeuchi E, Shinohara N, et al
    • Journal Title

      Autoimmunity

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790950
  • [Journal Article] Allogenic mixed chimerism prevented autoimmune thrombocytopenia in BXSB lupus mice receiving donor BMT with nonlymphoablative conditioning of low-dose TBI and anti CD40L mAb2011

    • Author(s)
      Takeuchi E
    • Journal Title

      Kitasato Med J

      Volume: 41(1) Pages: 50-56

    • NAID

      40018724980

    • Data Source
      KAKENHI-PROJECT-21790950
  • [Journal Article] Cognate interaction plays a key role in the surveillance of autoreactive B cells in induced mixed bone marrow chimerism in BXSB lupus mice2011

    • Author(s)
      Takeuchi E, Shinohara N, Takeuchi Y
    • Journal Title

      Autoimmunity

      Volume: 44(5) Pages: 363-372

    • Data Source
      KAKENHI-PROJECT-21790950
  • [Journal Article] Allogenic mixed chimerism prevented autoimmune thrombocytopenia in BXSB lupus mice receiving donor BMT with nonlymphoablative conditioning of low-dose TBI and anti CD40L mAb.2011

    • Author(s)
      Takeuchi E
    • Journal Title

      Kitasato Med.J.

      Volume: 41(in press)

    • NAID

      40018724980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790950
  • [Presentation] U1 RNP can induce NETosis to isolated mouse neutrophils through NOX2 independent pathway.2021

    • Author(s)
      竹内恵美子・大津 真・竹内康雄
    • Organizer
      第50回 日本免疫学会
    • Data Source
      KAKENHI-PROJECT-18K08217
  • [Presentation] X連鎖性慢性肉芽腫症モデルgp91phoxknock-out mouseへの肉芽腫形成誘導とNOX2依存的細胞死の関連について2020

    • Author(s)
      竹内恵美子・竹内康雄・大津真
    • Organizer
      第48回臨床免疫学会
    • Data Source
      KAKENHI-PROJECT-18K08217
  • [Presentation] X連鎖性慢性肉芽腫症モデルgp91phoxknock-out mouseへの肉芽腫形成誘導とNOX2依存的細胞死の関連について.2020

    • Author(s)
      竹内恵美子・竹内康雄・大津 真
    • Organizer
      第48回臨床免疫学会
    • Data Source
      KAKENHI-PROJECT-17K10006
  • [Presentation] The association between calcium influx and NETosis induced through the NADPH oxidase independent pathway2019

    • Author(s)
      Emiko Takeuchi
    • Organizer
      第48回日本免疫学会
    • Data Source
      KAKENHI-PROJECT-17K10006
  • [Presentation] In vitroにおけるマウス好中球のNETosis誘導と細胞外カルシウム濃度の関係について2019

    • Author(s)
      竹内恵美子、竹内康雄
    • Organizer
      第47回日本臨床免疫学会
    • Data Source
      KAKENHI-PROJECT-18K08217
  • [Presentation] The association between calcium influx and NETosis induced through the NADPH oxidase independent pathway2019

    • Author(s)
      EMIKO Takeuchi、YASUO Takeuchi, KAZUYA Iwabuchi
    • Organizer
      第48回日本免疫学会
    • Data Source
      KAKENHI-PROJECT-18K08217
  • [Presentation] In vitroにおけるマウス好中球のNetosis誘導と細胞外カルシウム濃度の関係について2019

    • Author(s)
      竹内恵美子
    • Organizer
      第47回日本臨床免疫学会
    • Data Source
      KAKENHI-PROJECT-17K10006
  • [Presentation] NADPH oxidase (NOX2)非依存的好中球NETosis誘導とミトコンドリアROS産生の関連について2018

    • Author(s)
      竹内恵美子 竹内康雄
    • Organizer
      第46回 臨床免疫学会
    • Data Source
      KAKENHI-PROJECT-17K10006
  • [Presentation] NADPH oxidase(NOX2)非依存的好中球Netosis誘導とミトコンドリアROS産生の関連について2018

    • Author(s)
      竹内恵美子 竹内康雄
    • Organizer
      第46回 臨床免疫学会
    • Data Source
      KAKENHI-PROJECT-18K08217
  • [Presentation] The association NADPH oxidase independent NETosis with acceleration of mitochondrial ROS production2018

    • Author(s)
      Emiko Takeuchi, Yasuo Takeuchi, Kazuya Iwabuchi
    • Organizer
      The 47th Annual meeting of the japanese Society for Immunology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08217
  • [Presentation] The association NADPH oxidase independent NETosis with acceleration of mitochondrial ROS production2018

    • Author(s)
      Emiko Takeuchi, Yasuo Takuchi, Kazuya Iwabuchi
    • Organizer
      The 47th Annual meeting of The Japanese Society for Immunolgy
    • Data Source
      KAKENHI-PROJECT-17K10006
  • [Presentation] .Quantitative analysis of Neutrophil extracellular traps (NETs) in lupus prone mouse using novel methods2017

    • Author(s)
      Shin Morisawa、Emiko Takeuchi, Yauso Takeuchi
    • Organizer
      The 46th Annual Meeting of The Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-26461490
  • [Presentation] .LupusモデルマウスBXSBを用いた好中球NETosisの新たな定量と定性解析2017

    • Author(s)
      竹内恵美子、森澤慎、竹内康雄
    • Organizer
      第45回 日本臨床免疫学会
    • Data Source
      KAKENHI-PROJECT-26461490
  • [Presentation] Quantitative analysis of Neutrophil extracellular traps (NETs) in lupus prone mouse using novel methods.2017

    • Author(s)
      Shin Morisawa、Emiko Takeuchi, Yauso Takeuchi
    • Organizer
      The 46th Annual Meeting of The Japanese Society for Immunology
    • Data Source
      KAKENHI-PROJECT-17K10006
  • [Presentation] LupusモデルマウスBXSBを用いた好中球NETosisの新たな定量と定性解析.2017

    • Author(s)
      竹内恵美子、森澤慎、竹内康雄
    • Organizer
      第45回 臨床免疫学会
    • Data Source
      KAKENHI-PROJECT-17K10006
  • [Presentation] 活性酸素はアリストロキアサンによる急性腎障害進行を抑制する2015

    • Author(s)
      竹内康雄、竹内恵美子、鎌田貢壽、河原克雅
    • Organizer
      第58回 日本腎臓学会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Presentation] 慢性肉芽腫症モデルマウスにおいてアリストロキア酸誘導性尿細管壊死性腎炎が増悪するメカニズムの解析.2015

    • Author(s)
      竹内恵美子、竹内康雄
    • Organizer
      第43回 臨床免疫学会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Presentation] 多様自己抗体陽性の免疫調節異常1症乳児例.2014

    • Author(s)
      緒方昌平、竹内恵美子、野元けい子、扇原義人、江波戸孝輔、紺野寿、坂東由紀、高木正稔、石井正浩
    • Organizer
      第5回関東甲信越免疫不全症研究会
    • Place of Presentation
      東京都千代田区
    • Year and Date
      2014-09-21
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Presentation] Dysfunction of selective suppression of auto-antibody production in SLE mice and reconstruction of this mechanism by induction of bone-marrow chimerism.2012

    • Author(s)
      Emiko TAKEUCHI, Yasuo TAKEUCHI, Nobukata SHINOHARA, Kazuya IWABUCHI
    • Organizer
      日本免疫学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Presentation] Dysfunction of selective suppression of auto-antibody production in SLE mice and reconstruction of this mechanism by induction of bone-marrow chimerism2011

    • Author(s)
      Takeuchi E, Katagiri H, Eshima K, Shinohara N, Takeuchi Y
    • Organizer
      1st Controversies in Rheumatorogy and Autoimmunity
    • Place of Presentation
      Italy
    • Data Source
      KAKENHI-PROJECT-21790950
  • [Presentation] Dysfunction of selective suppression of auto-antibody production in SLE mice and reconstruction of this mechanism by induction of bone-marrow chimerism.2011

    • Author(s)
      Takeuchi E, Katagiri H, et al
    • Organizer
      1st Controversies in Rheumatorogy and Autoimmunity
    • Place of Presentation
      Firence, Italy
    • Data Source
      KAKENHI-PROJECT-21790950
  • [Presentation] Dysfunction of selective suppression of auto-antibody production in SLE mouse and reconstruction of this mechanism by induction of bone-marrow chimerism2010

    • Author(s)
      Takeuchi E, Kobayashi K, Katagiri H, Eshima K, Shinohara N, Takeuchi Y
    • Organizer
      7th International congress on autoimmunity
    • Place of Presentation
      Ljubljana, Slovenia
    • Data Source
      KAKENHI-PROJECT-21790950
  • [Presentation] MHC完全不一致ドナーからの骨髄移植による自己免疫性血小板減少症の改善についての検討2010

    • Author(s)
      Takeuchi E, Kanoh Y
    • Organizer
      第57回日本臨床検査医学会学術集会
    • Place of Presentation
      Sinnjyuku, Japan
    • Data Source
      KAKENHI-PROJECT-21790950
  • [Presentation] MHC完全不一致ドナーからの骨髄移植による自己免疫性血小板減少症の改善についての検討2010

    • Author(s)
      Takeuchi E, Kanho Y
    • Organizer
      第57回日本臨床検査医学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Data Source
      KAKENHI-PROJECT-21790950
  • [Presentation] Dysfunction of selective suppression of auto-antibody production in SLE mouse and reconstruction of this mechanism by induction of bone-marrow chimerism.2010

    • Author(s)
      Takeuchi E, Kobayashi K., et al
    • Organizer
      7th International Congress on Autoimmunity
    • Place of Presentation
      Ljubljana, Slovenia
    • Data Source
      KAKENHI-PROJECT-21790950
  • [Presentation] A threshold in expression levels of gp91phox transgene limits the degree of functional correction in granulocytes after gene therapy for CGD2009

    • Author(s)
      Takeuchi Y, Otsu M, Onodera M, Takeuchi E, Nakauchi H
    • Organizer
      17th Annual congress of the European society of gene & cell therapy
    • Place of Presentation
      Hannover, Gernany
    • Data Source
      KAKENHI-PROJECT-21790950
  • [Presentation] Stable supply of functional reconstituted neutrophils achieved by transplantation of allogeneic umbilical cord blood induced remission of inflammatory state in X-CGD mice.

    • Author(s)
      E Takeuchi, Y Takeuchi
    • Organizer
      18th European society of gene and cell therapy.
    • Place of Presentation
      Hague, Netherland.
    • Year and Date
      2014-10-23 – 2014-10-26
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Presentation] MHC不一致ドナーからの臍帯血移植による慢性肉芽腫症モデルマウスの治療.

    • Author(s)
      竹内恵美子、田村昌也、竹内康雄
    • Organizer
      第42回 日本臨床免疫学会
    • Place of Presentation
      東京都新宿区
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Presentation] Development of experimental animal model to assess of cause for disappearance of gene-corrected granulocytes as a clinical problem of human gene therapy of X-CGD

    • Author(s)
      Takeuchi Y, Takeuchi E, Otsu S
    • Organizer
      European Academy of Allergy and Clinical Immunology
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Presentation] Characterization of non-invariant NKT cells in visceral adipose tissue.

    • Author(s)
      Satoh M, Eshima K, Takeuchi E, Iwabuchi K.
    • Organizer
      Annual Meeting of The Japanese Society for Immunology
    • Place of Presentation
      Makuhari, Japan
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Presentation] Development of gene therapy model for disappearance of gene-corrected granulocytes by immunological deletion associated with antigenicity of newly expressed GP91phox protein in X-CGD.

    • Author(s)
      Takeuchi Y, Takeuchi E, Otsu S
    • Organizer
      Controversies in Rheumatorogy and Autoimmunity
    • Place of Presentation
      Budapest, Hungary.
    • Data Source
      KAKENHI-PROJECT-24591469
  • [Presentation] The role of immunocompetent cells in the development of nickel-induced allergic contact dermatitis

    • Author(s)
      Okuno H, Satoh M, Takeuchi E, Eshima K, Tamauchi H, Iwabuchi K
    • Organizer
      Annual Meeting of The Japanese Society for Immunology
    • Place of Presentation
      Makuhari, Japan
    • Data Source
      KAKENHI-PROJECT-24591469
  • 1.  TAKEUCHI Yasuo (60286359)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 31 results
  • 2.  大津 真 (30361330)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  IWABUCHI Kazuya (20184898)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 4.  川島 永子 (90342774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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