Mie Yasuhiro 三重安弘

… Alternative Names

MIE Yasuhiro 三重安弘

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Researcher Number	00415746
Other IDs
Affiliation (Current)	2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究グループ長
Affiliation (based on the past Project Information) *help	2017 – 2024: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究グループ長 2015 – 2016: 国立研究開発法人産業技術総合研究所, 生物プロセス研究部門, 主任研究員 2011 – 2014: 独立行政法人産業技術総合研究所, 生物プロセス研究部門, 主任研究員 2008 – 2009: National Institute of Advanced Industrial Science and Technology, ゲノムファクトリー研究部門, 研究員 2007: National Institute of Advanced Industrial Science and Technology, ゲノムファクトリー研究部門, 研究員 2006: 独立行政法人産業技術総合研究所, ゲノムファクトリー研究部門, 研究員
Review Section/Research Field	Principal Investigator Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Medium-sized Section 27:Chemical engineering and related fields Except Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
Keywords	Principal Investigator 電気化学アッセイ / 薬物代謝 / 酸化還元制御 / 電気化学分析 / ミクロソーム / 電解合成 / ナノ構造界面 / 電極界面 / 直接電子移動 / 分子コーティング … More / 構造規制電極 / P450ファミリー / 立体選択性 / 酵素反応制御 / 物質生産 / 微細孔電極 / シトクロムP450 / ビタミンD3 / 多孔質電極 / 大腸菌 / 免疫抑制阻害 / ナノ孔電極 / ジオキシゲナーゼ / サイトグロビン / 酸化還元酵素 / 電子移動反応 / トリプトファン代謝 / ニューログロビン / 金ナノ粒子 / ナノ構造電極 / ヘム蛋白質 / インドールアミン2,3-ジオキシゲナーゼ / 金属蛋白質 / 核酸医薬 / 核酸-蛋白質相互作用 / microRNA / anti-miRNAオリゴ / Ago蛋白質 / miRNA / 機能性界面 / P450 / ナノ構造 / ナノ構造界面電極 / ミクロソームアッセイ / 脂質膜 / 微細構造界面 / 疎水性薄膜 / CYPミクロソーム / 有用物質生産 / 電気化学酵素反応 / 微粒子集積界面 / スパッタリング法 / ヒトシトクロムP450(CYP) / 分析化学 / ポリイオン薄膜 / 電子移動 / CYP / 薄膜コーティング / 電気化学活性計測 / 配向固定 / 膜結合蛋白 / 薬物代謝活性 / 一塩基多型 / シトクロムP450(CYP) … More Except Principal Investigator ナノレベル構造 / 酸化還元補酵素 / NAD+/NADH / ラジカル中間体 / NADH / ポリペプチド / ナノ構造 / 水素付加反応 / 二量体 / 過電圧 / 電極界面 / レドックス / ニコチンアミドアデニンジヌクレオチド Less

Precise molecular conversion platform using electrochemically-driven enzymatic reactions and its application to middle molecule drug discoveryPrincipal Investigator
- Principal Investigator
  
  三重安弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of electrode interface for NAD + / NADH redox reaction with high efficiency equivalent to in vivo
- Principal Investigator
  
  冨永昌人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Saga University
Redox control of bacterial cells using metal porous materialsPrincipal Investigator
- Principal Investigator
  
  三重安弘
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 27:Chemical engineering and related fields
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Redox control of disease-related metalloproteins and its application to drug developmentPrincipal Investigator
- Principal Investigator
  
  三重安弘
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Sensitive assay for nucleic acid and protein interactions and its application for nucleic acid medicinesPrincipal Investigator
- Principal Investigator
  
  Mie Yasuhiro
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Highly efficient and sensitive analysis of multiplex drug metabolism reactionsPrincipal Investigator
- Principal Investigator
  
  Mie Yasuhiro
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of microsome electrode for efficient drugMetabolism assayPrincipal Investigator
- Principal Investigator
  
  MIE Yasuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Electrochemically-driven CYP reactions with nanostructured electrode surfacesPrincipal Investigator
- Principal Investigator
  
  MIE Yasuhiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  National Institute of Advanced Industrial Science and Technology
直接電気化学法を用いたCYPのハイスループット薬物代謝活性計測ツールの開発Principal Investigator
- Principal Investigator
  
  三重安弘
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  National Institute of Advanced Industrial Science and Technology

[Journal Article] Efficacy of films of uncapped gold nanoparticle as electrodes for direct electron transfer to redox proteins2024
- Author(s)
  Akiyama Kentaro、Okabe Hirotaka、Motomura Taisei、Matsuda Naoki、Mie Yasuhiro
- Journal Title
  
  Electrochemistry Communications
  
  Volume: 161 Pages: 107695-107695
- DOI
  10.1016/j.elecom.2024.107695
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18932, KAKENHI-PROJECT-19K07024
[Journal Article] Nanostructured gold thin film electrode derived from surfactant-free gold nanoparticles for enhanced electrocatalysis2023
- Author(s)
  Mie Yasuhiro、Okabe Hirotaka、Mikami Chitose、Motomura Taisei、Matsuda Naoki
- Journal Title
  
  Electrochemistry Communications
  
  Volume: 146 Pages: 107415-107415
- DOI
  10.1016/j.elecom.2022.107415
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07024
[Journal Article] Electrochemical Molecular Conversion of α-Keto Acid to Amino Acid at a Low Overpotential Using a Nanoporous Gold Catalyst2021
- Author(s)
  Mie Yasuhiro, Katagai Shizuka, Mikami Chitose
- Journal Title
  
  International Journal of Molecular Science
  
  Volume: 22 Issue: 17 Pages: 9442-9442
- DOI
  10.3390/ijms22179442
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07024
[Journal Article] Nanoporous gold based electrodes for electrochemical studies of human neuroglobin2020
- Author(s)
  三重安弘、髙橋杏佳、糸賀友香、末吉健大、辻野博文、山下沢、宇野公之
- Journal Title
  
  Electrochemistry Communications
  
  Volume: 110 Pages: 106621-106621
- DOI
  10.1016/j.elecom.2019.106621
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07024, KAKENHI-PROJECT-16K08218
[Journal Article] Electrochemical Oxidation of Monosaccharides at Nanoporous Gold with Controlled Atomic Surface Orientation and Non-Enzymatic Galactose Sensing2020
- Author(s)
  Mie Yasuhiro、Katagai Shizuka、Ikegami Masiki
- Journal Title
  
  Sensors
  
  Volume: 20 Issue: 19 Pages: 5632-5632
- DOI
  10.3390/s20195632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07024
[Journal Article] Facile control of surface crystallographic orientation of anodized nanoporous gold catalyst and its application for highly efficient hydrogen evolution reaction2020
- Author(s)
  Mie Yasuhiro、Takayama Haruka、Hirano Yu
- Journal Title
  
  Journal of Catalysis
  
  Volume: 389 Pages: 476-482
- DOI
  10.1016/j.jcat.2020.06.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07024, KAKENHI-PROJECT-17K05917
[Journal Article] Redox State Control of Human Cytoglobin by Direct Electrochemical Method to Investigate Its Function in Molecular Basis2020
- Author(s)
  Mie Yasuhiro、Takahashi Kyoka、Torii Ryo、Jingkai Shen、Tanaka Takumi、Sueyoshi Kenta、Tsujino Hirofumi、Yamashita Taku
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 68 Issue: 8 Pages: 806-809
- DOI
  10.1248/cpb.c20-00175
- NAID
  130007883281
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2020-08-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07024
[Journal Article] Electrochemically boosted cytochrome P450 reaction that efficiently produces 25-hydroxyvitamin D32020
- Author(s)
  三重安弘、安武義晃、高山晴香、田村具博
- Journal Title
  
  Journal of Catalysis
  
  Volume: 384 Pages: 30-36
- DOI
  10.1016/j.jcat.2020.02.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07024, KAKENHI-PROJECT-16K08218
[Journal Article] ナノ構造電極による酸化還元酵素の活性制御2020
- Author(s)
  三重安弘、安武義晃
- Journal Title
  
  バイオサイエンスとインダストリー
  
  Volume: 78 Pages: 496-497
- Data Source
  KAKENHI-PROJECT-19K07024
[Journal Article] Anodized gold surface enables mediator-free and low-overpotential electrochemical oxidation of NADH: A facile method for the development of an NAD+-dependent enzyme biosensor2019
- Author(s)
  三重安弘、安武義晃、池上真志樹、田村具博
- Journal Title
  
  Sensors and Actuators B: Chemical
  
  Volume: 288 Pages: 512-518
- DOI
  10.1016/j.snb.2019.03.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08218
[Journal Article] Adsorptive Stripping Voltammetry for the Determination of Dissolved Oxygen Using a Mesoporous Pt Microelectrode2019
- Author(s)
  Masiki Ikegami, Yu Hirano, Yasuhiro Mie, Yasuo Komatsu
- Journal Title
  
  Journal of The Electrochemical Society
  
  Volume: 166 Issue: 6 Pages: B542-B546
- DOI
  10.1149/2.0021908jes
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K05917, KAKENHI-PROJECT-16K08218, KAKENHI-PROJECT-16H05106
[Journal Article] Function Control of Anti-microRNA Oligonucleotides Using Interstrand Cross-Linked Duplexes2018
- Author(s)
  Yasuhiro Mie, Yu Hirano, Keiko Kowata, Akiyoshi Nakamura, Mayu Yasunaga, Yoshihiro Nakajima, Yasuo Komatsu
- Journal Title
  
  MOLECULAR THERAPY-NUCLEIC ACIDS
  
  Volume: 10 Pages: 64-74
- DOI
  10.1016/j.omtn.2017.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08218, KAKENHI-PROJECT-17K05917, KAKENHI-PROJECT-16H05106, KAKENHI-PROJECT-16H03295
[Journal Article] Fabrication and characterization of nanoporous gold on microelectrode.2016
- Author(s)
  Ikegami, M., Hirano, Y., Mie, Y. and Komatsu, Y.
- Journal Title
  
  J. Electroanalytical Chem.
  
  Volume: 783 Pages: 188-191
- DOI
  10.1016/j.jelechem.2016.11.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293030, KAKENHI-PROJECT-25460055
[Journal Article] Nanoporous structure of gold electrode fabricated by anodization and its efficacy for direct electrochemistry of human cytochrome P450.2016
- Author(s)
  Mie, Y., Ikegami, M. and Komatsu, Y.
- Journal Title
  
  10.1246/cl.160164
  
  Volume: 45 Issue: 6 Pages: 640-642
- DOI
  10.1246/cl.160164
- NAID
  130005155033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293030, KAKENHI-PROJECT-25460055
[Journal Article] p-Aminothiophenol modification on gold surface improves stability for electrochemically driven cytochrome P450 microsome activity.2014
- Author(s)
  Mie, Y., Tateyama, E. and Komatsu, Y.
- Journal Title
  
  Electrochim. Acta
  
  Volume: 115 Pages: 364-369
- DOI
  10.1016/j.electacta.2013.10.170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293030, KAKENHI-PROJECT-25460055, KAKENHI-PROJECT-25620121
[Journal Article] End-tether Structure of DNA Alters Electron-transfer Pathway of Redox-labeled Oligo-DNA Duplex at Electrode Surface2012
- Author(s)
  Mie, Y., Kojima, N., Kowata, K. and Komatsu, Y
- Journal Title
  
  Chemistry Letters
  
  Volume: 41 Issue: 1 Pages: 62-64
- DOI
  10.1246/cl.2012.62
- NAID
  130004426305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510239, KAKENHI-PROJECT-23790065
[Journal Article] Electrochemical prperties of interstrand cross-linked DNA duplexes labeled with nile-blue2012
- Author(s)
  三重　安弘
- Journal Title
  
  Langmuir
  
  Volume: 28 Issue: 49 Pages: 17211-17216
- DOI
  10.1021/la3036538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790065
[Journal Article] Gold sputtered electrode surfaces enhance direct electron transfer reactions of human cytochrome P450s2010
- Author(s)
  三重安弘
- Journal Title
  
  Electrochemistry Communications (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790048
[Journal Article] Gold sputtered electrode surfaces enhance direct electron transfer reactions of human cytochrome P450s2010
- Author(s)
  三重安弘、池上真志樹、小松康雄
- Journal Title
  
  Electrochem. Commun. 12巻
  
  Pages: 680-683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790048
[Journal Article] Electrochemically driven drug metabolism reaction by membrane containing human cytochrome P4502009
- Author(s)
  三重安弘
- Journal Title
  
  Journal of the American Chemical Society VOL.131
  
  Pages: 6646-6647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790048
[Journal Article] Electrochemically driven drug metabolism reaction by membrane containing human cytochrome P4502009
- Author(s)
  三重安弘、鈴木正昭、小松康雄
- Journal Title
  
  J. Am. Chem. Soc. 131巻
  
  Pages: 6646-6647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790048
[Journal Article] Electrochemically driven drug metabolism reaction by membrane containing human cytochrome P450
- Author(s)
  三重安弘
- Journal Title
  
  Journal of the American Chemical Society (in press.)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790048
[Patent] 酸化還元タンパク質固定化ナノ構造電極2009
- Inventor(s)
  三重安弘
- Industrial Property Rights Holder
  独立行政法人産業技術総合研究所
- Industrial Property Number
  2009-221129
- Filing Date
  2009-09-25
- Data Source
  KAKENHI-PROJECT-20790048
[Patent] 酸化還元タンパク質固定化ナノ構造電極2009
- Inventor(s)
  三重安弘, 池上真志樹, 小松康雄
- Industrial Property Rights Holder
  独立行政法人産業技術総合研究所
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2009-221129
- Filing Date
  2009-09-25
- Data Source
  KAKENHI-PROJECT-20790048
[Patent] 酸化還元タンパク質固定化ナノ構造電極2009
- Inventor(s)
  三重安弘、池上真志樹、小松康雄
- Industrial Property Rights Holder
  独立行政法人産業技術総合研究所
- Industrial Property Number
  2009-221129
- Filing Date
  2009-09-25
- Data Source
  KAKENHI-PROJECT-20790048
[Patent] 酸化還元タンパク質含有脂質膜が固定化された電極2008
- Inventor(s)
  三重安弘、小松康雄
- Industrial Property Rights Holder
  独立行政法人産業技術総合研究所
- Industrial Property Number
  2008-253720
- Filing Date
  2008-09-30
- Data Source
  KAKENHI-PROJECT-20790048
[Patent] 酸化還元タンパク質含有脂質膜が固定化された電極2008
- Inventor(s)
  三重安弘
- Industrial Property Rights Holder
  独立行政法人産業技術総合研究所
- Industrial Property Number
  2008-253720
- Filing Date
  2008-09-30
- Data Source
  KAKENHI-PROJECT-20790048
[Presentation] 金ナノ粒子電極によるP450酵素のレドックス制御とビタミンD3の水酸化2024
- Author(s)
  三重安弘、見上千歳、安武義晃、松田直樹
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K18932
[Presentation] 金ナノ粒子薄層電極を活用した生物電気化学技術の実用化に向けて2024
- Author(s)
  秋山健太郎、三重安弘、岡部浩隆、本村大成、松田直樹
- Organizer
  SATテクノロジー・ショーケース2024
- Data Source
  KAKENHI-PROJECT-22K18932
[Presentation] 金ナノ粒子電極によるP450酵素のレドックス制御とビタミンD3の水酸化2024
- Author(s)
  三重安弘、見上千歳、安武義晃、松田直樹
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] 「ナノ触媒 × 酵素」による高効率なファインケミカル合成技術2023
- Author(s)
  三重安弘
- Organizer
  埼玉県産業振興公社第３回連携研究シーズ研究会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Nanostructured Gold Catalysts for Efficient Redox Control of Enzymes toward Their Investigations and Utilizations2023
- Author(s)
  三重安弘
- Organizer
  MRM2023/IUMRS-ICA2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Electrochemically-driven P450 reactions to produce pharmaceutical hydroxyvitamin D32023
- Author(s)
  三重安弘、見上千歳、安武義晃
- Organizer
  The 23rd International Conference on Cytochrome P450
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Electrochemically boosted P450 reactions to produce pharmaceutical vitamin D32023
- Author(s)
  三重安弘、見上千歳、安武義晃
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] 酵素・微生物を電気エネルギーで駆動・制御して有用物質をつくる2023
- Author(s)
  三重安弘
- Organizer
  BioJapan 2023
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Electrochemically-driven P450 reactions to produce pharmaceutical hydroxyvitamin D32023
- Author(s)
  三重安弘、見上千歳、安武義晃
- Organizer
  The 23rd International Conference on Cytochrome P450
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18932
[Presentation] 酵素・微生物を電気エネルギーで駆動・制御して有用物質をつくる2023
- Author(s)
  三重安弘
- Organizer
  BioJapan 2022
- Data Source
  KAKENHI-PROJECT-22K18932
[Presentation] Nanostructured Gold Catalysts for Efficient Redox Control of Enzymes toward Their Investigations and Utilizations2023
- Author(s)
  三重安弘
- Organizer
  MRM2023/IUMRS-ICA2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18932
[Presentation] インドールアミン2,3-ジオキシゲナーゼの電気化学的な阻害アッセイ法の開発と阻害剤探索2023
- Author(s)
  三重安弘、見上千歳、安武義晃、重村優貴、辻野博文、山下沢
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Electrochemically boosted P450 reactions to produce pharmaceutical vitamin D32023
- Author(s)
  三重安弘、見上千歳、安武義晃
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K18932
[Presentation] 「ナノ触媒 × 酵素」による高効率なファインケミカル合成技術2023
- Author(s)
  三重安弘
- Organizer
  埼玉県産業振興公社第3回連携研究シーズ研究会
- Data Source
  KAKENHI-PROJECT-22K18932
[Presentation] バイオマス由来物質のナノ電極触媒を用いた還元処理によるアミノ酸への変換2023
- Author(s)
  三重安弘、片貝静香、見上千歳
- Organizer
  第2回環境化学物質3学会合同大会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] 酵素反応を継続的に低環境負荷で進行させるための導電性材料2022
- Author(s)
  三重安弘、安武義晃
- Organizer
  第 20 回産総研・産技連 LS-BT 合同研究発表会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] 酵素反応を継続的に低環境負荷で進行させるための導電性材料2022
- Author(s)
  三重安弘、安武義晃
- Organizer
  第20回産総研・産技連LS-BT合同研究発表会
- Data Source
  KAKENHI-PROJECT-22K18932
[Presentation] 多彩な形態のナノ多孔質金を用いた薬物代謝センサの開発2022
- Author(s)
  芝介駿、後藤昴、國武雅司、三重安弘、加藤大、丹羽修、松口正信
- Organizer
  第82回分析化学討論会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] 構造規制電極を用いた微生物電気化学触媒による医薬中間体の生成2022
- Author(s)
  三重安弘、見上千歳、安武義晃、中島信孝
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Controlling Surface Structure of Nanoporous Gold Catalyst toward Enzymatic Production of Valuable Molecules2022
- Author(s)
  三重安弘、見上千歳、安武義晃
- Organizer
  第32回日本MRS年次大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18932
[Presentation] 電気的酵素反応を活用する高効率・低環境負荷なファインケミカル合成2022
- Author(s)
  三重安弘
- Organizer
  BioJapan 2022
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] 電気的酵素反応を活用する高効率・低環境負荷なファインケミカル合成2022
- Author(s)
  三重安弘
- Organizer
  BioJapan 2022
- Data Source
  KAKENHI-PROJECT-22K18932
[Presentation] 電気化学エネルギーを用いる酵素反応の活用技術2022
- Author(s)
  三重安弘
- Organizer
  令和４年度産学連携技術シーズ発表会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Controlling Surface Structure of Nanoporous Gold Catalyst toward Enzymatic Production of Valuable Molecules2022
- Author(s)
  三重安弘、見上千歳、安武義晃
- Organizer
  第32回日本MRS年次大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Redox control of human indoleamine 2,3-dioxygenase at nanostructured electrode surface and its inhibitor screening2022
- Author(s)
  三重安弘、見上千歳、安武義晃、重村優貴、辻野博文、山下沢
- Organizer
  第 60 回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] ナノ構造触媒の精密制御とSDGsに資する有用物質生産2021
- Author(s)
  三重安弘、安武義晃
- Organizer
  第19回産総研・産技連LS-BT合同研究発表会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] 構造規制電極界面を用いる酸化還元酵素の活性制御2021
- Author(s)
  三重安弘
- Organizer
  酵素工学研究会第86回講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Controlling Nanostructure of Electrode Surface toward Efficient Enzymatic Bioelectrocatalysis2021
- Author(s)
  三重安弘
- Organizer
  The 11th International Conference on Flexible and Printed Electronics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] ナノ電極触媒によるNADHの効率的酸化とNAD+-依存型酵素の電気化学的活用2021
- Author(s)
  三重安弘、安武義晃、田村具博
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] SDGsに資するバイオものづくり技術2021
- Author(s)
  三重安弘
- Organizer
  BioJapan 2021
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Electrochemical studies of human neuroglobin and cytoglobin using nanostructured electrode2020
- Author(s)
  三重安弘、髙橋杏佳、糸賀友香、末吉健大、鳥井遼、Shen Jingkai、田中匠、辻野博文、山下沢
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] 電気化学P450反応によるビタミンD3の水酸化2020
- Author(s)
  三重安弘、安武義晃、高山晴香、田村具博
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Anodized gold surface enables mediator-free bioelectrocatalysis of redox enzymes2019
- Author(s)
  三重安弘、安武義晃、池上真志樹、田村具博
- Organizer
  第57回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] Tuning Nanoporous Gold Catalyst toward Efficient Biosensing and Bioproduction Platforms2019
- Author(s)
  三重安弘
- Organizer
  RCAS & AIST Bilateral Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] クロスリンク２本鎖構造によるanti-miRNAオリゴの細胞内局在への影響2019
- Author(s)
  平野悠、扇谷仁希、千高佐知子、三重安弘、小松康雄
- Organizer
  核酸医薬学会　第5回年会
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] Tuning Nanoporous Gold Catalyst toward Efficient Biosensing and Bioproduction Platforms2019
- Author(s)
  三重安弘
- Organizer
  RCAS & AIST Bilateral Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] ナノ孔電極を用いるCYP反応の高効率な電気化学制御と物質変換への応用2019
- Author(s)
  三重安弘、池上真志樹
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] Tuning Nanoporous Gold Catalyst and its Efficacy for Bioelectrocatalysis2019
- Author(s)
  三重安弘、安武義晃、高山晴香
- Organizer
  International Symposium on Porous Materials 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Anodized gold surface enables mediator-free bioelectrocatalysis of redox enzymes2019
- Author(s)
  三重安弘、安武義晃、池上真志樹、田村具博
- Organizer
  第57回日本生物物理学会
- Data Source
  KAKENHI-PROJECT-19K07024
[Presentation] Tuning Nanoporous Gold Catalyst and its Efficacy for Bioelectrocatalysis2019
- Author(s)
  三重安弘、安武義晃、高山晴香
- Organizer
  International Symposium on Porous Materials 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] ナノ構造触媒を活用するバイオものづくりおよびバイオセンシング技術2019
- Author(s)
  三重安弘、池上真志樹、安武義晃
- Organizer
  第18回産総研・産技連LS-BT合同研究発表会
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] 微細構造白金マイクロ電極を用いた溶存酸素の検出2019
- Author(s)
  池上真志樹、平野悠、三重安弘
- Organizer
  応用物理学会春季学術講演会
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] マーカー物質のその場計測2018
- Author(s)
  三重安弘、安武義晃
- Organizer
  サステナブル技術連携促進シンポジウム「ヘルスケア」
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] Highly sensitive detections of protein-nucleic acid interactions and redox enzyme reactions using nanostructured electrode2018
- Author(s)
  三重安弘、小松康雄
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] クロスリンク２本鎖構造を有するanti-miRNAオリゴ核酸の細胞内動態2018
- Author(s)
  平野悠、扇谷仁希、三重安弘、小綿恵子、小松康雄
- Organizer
  核酸医薬学会　第4回年会
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] 医薬品生産および物質検出を指向したビタミンD水酸化酵素の電気化学反応系の構築2017
- Author(s)
  佐々木ひかり、三重安弘、安武義晃、田村具博
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-25460055
[Presentation] Improvement in efficiency of electrochemically-driven cytochrome P450 reactions by nanoporous structured electrode2017
- Author(s)
  三重安弘，池上真志樹，小松康雄
- Organizer
  2017年度生命科学系合同年次大会
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] アノード溶解によるナノポーラスゴールド形成の電極サイズ依存性2017
- Author(s)
  池上真志樹、平野悠、三重安弘、小松康雄
- Organizer
  応用物理学会春季学術講演会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25460055
[Presentation] 架橋化構造を有するanti-miRNAオリゴによる神経膠芽腫細胞の増殖抑制効果2017
- Author(s)
  三重安弘，平野悠，小綿恵子，小松康雄
- Organizer
  日本核酸医薬学会第３回年会
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] Structure-function relationship of anti-miRNA oligonucleotides modified with interstrand cross-links2016
- Author(s)
  三重安弘、小綿恵子、平野悠、中村彰良、安永茉由、中島芳浩、小松康雄
- Organizer
  RNA2016
- Place of Presentation
  京都国際会館（京都）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] 高効率な物質生産および高感度な物質検出を指向した電気化学酵素反応基盤2016
- Author(s)
  三重安弘
- Organizer
  微生物研究の新展開
- Place of Presentation
  秋葉原コンベンションホール（東京都）
- Year and Date
  2016-01-13
- Data Source
  KAKENHI-PROJECT-25460055
[Presentation] クロスリンク２本鎖構造を有する anti-miRNA オリゴ核酸の構造と miRNA 阻害活性との相関2016
- Author(s)
  三重安弘、小綿恵子、平野悠、中村彰良、安永茉由、中島芳浩、小松康雄
- Organizer
  日本核酸医薬学会第２回年会
- Place of Presentation
  東京理科大学（東京）
- Data Source
  KAKENHI-PROJECT-16K08218
[Presentation] Electrochemically-assisted enzyme reaction: low cost production and sensitive detection of pharmaceuticals2016
- Author(s)
  三重安弘、池上真志樹、小松康雄
- Organizer
  第15回 LS-BT合同研究発表会
- Place of Presentation
  産業技術総合研究所（つくば）
- Year and Date
  2016-02-02
- Data Source
  KAKENHI-PROJECT-25460055
[Presentation] Electrochemical Analysis of P450s in Microfluidic Channel2015
- Author(s)
  三重安弘、小松康雄
- Organizer
  日本生物物理学会第53回年会
- Place of Presentation
  金沢大学（金沢）
- Year and Date
  2015-09-16
- Data Source
  KAKENHI-PROJECT-25460055
[Presentation] ナノ構造電極上でのシトクロムP450 153A13aの電気化学触媒反応2014
- Author(s)
  三重安弘、藤田尚也、長敏夫、小松康雄
- Organizer
  日本生物物理学会第52回年会
- Place of Presentation
  札幌コンベンションセンター（札幌）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-25460055
[Presentation] P450電気化学触媒の基盤技術2014
- Author(s)
  三重安弘、池上真志喜、小松康雄
- Organizer
  持続可能な社会を築く触媒技術の可能性
- Place of Presentation
  北海道大学（札幌）
- Year and Date
  2014-08-29
- Data Source
  KAKENHI-PROJECT-25460055
[Presentation] CYP薬剤代謝アッセイ及びCYP反応による医薬品代謝物生産の効率化技術の開発2013
- Author(s)
  三重安弘
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  日本薬学会第133 年会
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] Development of Electrode Surface for Cost-effective Assay of CYP Microsomes2012
- Author(s)
  三重　安弘
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  北海道大学高等教育推進機構（北海道）
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] 有機薄膜電極上での P450 反応の電気化学制御と応用2012
- Author(s)
  三重安弘
- Organizer
  第50回日本生物物理学会
- Place of Presentation
  名古屋大学(愛知県)
- Year and Date
  2012-09-23
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] Electrochemistry of Interstrand Cross-linked Redox-DNAs2012
- Author(s)
  三重安弘
- Organizer
  The 39th International Sympposium on Nucleic Acid Chemistry
- Place of Presentation
  名古屋大学(愛知県)
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] 、レドックス DNA の電極上での配向及び電子移動に及ぼす DNA 末端テザー構造の影響2012
- Author(s)
  三重安弘
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] Electrochemically-driven P450 Reactions toward Efficient Drug Metabolism Analysis and Bioproductioin2012
- Author(s)
  三重安弘
- Organizer
  50th Anniversary Symposium on Cytochrome P450
- Place of Presentation
  九州大学(福岡県)
- Year and Date
  2012-12-02
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] Development of Electrode Surface for Cost-effective Assay of CYP Microsomes2012
- Author(s)
  三重安弘
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] Effect of End-tether Structure of Redox-DNA on its Electron Transfer Pathway at Electrode Surface2011
- Author(s)
  三重　安弘
- Organizer
  第38回国際核酸化学シンポジウム
- Place of Presentation
  北海道大学クラーク会館（北海道）
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] Effect of End-tether Structure of Redox-DNA on its Electron Transfer Pathway at Electrode Surface2011
- Author(s)
  三重安弘
- Organizer
  第38回国際核酸化学シンポジウム
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] ナノ構造電極を利用したヒトCYPミクロソームの簡便・迅速アッセイの検討2010
- Author(s)
  三重安弘
- Organizer
  日本薬学会第130年会
- Place of Presentation
  桃太郎アリーナ(岡山)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20790048
[Presentation] ナノ構造電極を利用したヒトCYPミクロソームの簡便・迅速アッセイの検討2010
- Author(s)
  三重安弘
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20790048
[Presentation] Electrochemically-driven Drug Metabolism by Human Cytochrome P450 Immobilized on Hydrophobic Electrode Surface2009
- Author(s)
  三重安弘
- Organizer
  16^<th> International Conference on Cytochrome P450
- Place of Presentation
  万国津梁館(沖縄)
- Year and Date
  2009-06-23
- Data Source
  KAKENHI-PROJECT-20790048
[Presentation] ヒトシトクロムP450ミクロソームの簡便・安価・迅速アッセイ法の開発2009
- Author(s)
  三重安弘
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20790048
[Presentation] Electrochemically-driven Drug Metabolism by Human Cytochrome P450 Immobilized on Hydrophobic Electrode Surface2009
- Author(s)
  三重安弘
- Organizer
  16th International Conference on Cytochrome P450
- Place of Presentation
  名護
- Year and Date
  2009-06-23
- Data Source
  KAKENHI-PROJECT-20790048
[Presentation] ナノ構造を有する電極を電子供給基質としたシトクロムP450反応の駆動と計測2009
- Author(s)
  三重安弘
- Organizer
  第47回日本生物物理学会年会
- Place of Presentation
  徳島
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-20790048
[Presentation] ナノ構造を有する電極を電子供給基質としたシトクロムP450反応の駆動と計測2009
- Author(s)
  三重安弘
- Organizer
  第47回日本生物物理学会年会
- Place of Presentation
  アスティ徳島(徳島)
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-20790048
[Presentation] ヒト薬物代謝酵素 (CYP) の電気化学的活性計測の検討2008
- Author(s)
  三重安弘
- Organizer
  日本薬学会第128年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-18790036
[Presentation] 疎水性電極界面を用いた膜結合型シトクロムP450の電気化学分析2008
- Author(s)
  三重安弘
- Organizer
  日本生物物理学会第46回年会
- Place of Presentation
  福岡
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-20790048
[Presentation] CYP2C9の電極上への固定化と電気化学的薬物代謝活性評価2007
- Author(s)
  三重安弘
- Organizer
  日本分析化学会第56年会
- Place of Presentation
  徳島大学
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-18790036
[Presentation] 電極を用いたシトクロムP450(CYP)の簡便活性計瀾の検討2007
- Author(s)
  三重安弘
- Organizer
  第68回分析化学討論会
- Place of Presentation
  宇都宮大学
- Year and Date
  2007-05-19
- Data Source
  KAKENHI-PROJECT-18790036
[Presentation] レドックスDNAの電極上での配向及び電子移動に及ぼすDNA末端テザー構造の影響
- Author(s)
  三重　安弘
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] レドックスDNAの電子移動反応に及ぼす二本鎖内架橋の影響
- Author(s)
  三重安弘、小綿恵子、小松康雄
- Organizer
  日本生物物理学会第５１回年会
- Place of Presentation
  京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-25460055
[Presentation] 有機薄膜電極からの電子供給によるヒトＣＹＰ発現系ミクロソームの薬物代謝反応
- Author(s)
  三重安弘、館山絵美、小松康雄
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本）
- Data Source
  KAKENHI-PROJECT-25460055
[Presentation] Electrochemically-driven P450 Reactions toward Efficient Drug Metabolism Analysis and Bioproductioin
- Author(s)
  三重　安弘
- Organizer
  50th Anniversary Symposium on Cytochrome P450
- Place of Presentation
  九州大学
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] 有機薄膜電極上でのP450反応の電気化学制御と応用
- Author(s)
  三重　安弘
- Organizer
  第50回日本生物物理学会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] CYP薬剤代謝アッセイ及びCYP反応による医薬品代謝物生産の効率化技術の開発
- Author(s)
  三重　安弘
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] 薬物代謝酵素P450を電気を使って効率よく制御する技術の開発
- Author(s)
  三重安弘
- Organizer
  HiNTセミナー
- Place of Presentation
  Ｒ＆Ｂパーク札幌大通サテライト（札幌）
- Data Source
  KAKENHI-PROJECT-25460055
[Presentation] Electrochemistry of Interstrand Cross-linked Redox-DNAs
- Author(s)
  三重　安弘
- Organizer
  The 39th International Sympposium on Nucleic Acid Chemistry
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-23790065
[Presentation] スパッタ金電極上での電気化学P450反応の評価
- Author(s)
  三重安弘、館山絵美、小松康雄
- Organizer
  第23回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  武蔵野大学（東京都）
- Data Source
  KAKENHI-PROJECT-25460055
[Presentation] 分子内架橋によるナイルブルー修飾DNAの電子移動反応制御
- Author(s)
  三重安弘、小綿恵子、小松康雄
- Organizer
  第7回バイオ関連化学シンポジウム
- Place of Presentation
  名古屋大学（名古屋）
- Data Source
  KAKENHI-PROJECT-25460055

1. 辻野博文 (10707144)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. 安武義晃 (20415756)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 冨永昌人 (70264207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山本雅博 (60182648)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 小松康雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
6. 平野悠

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Mie Yasuhiro 三重 安弘

MIE Yasuhiro 三重 安弘

Research Projects

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Co-Researchers

Precise molecular conversion platform using electrochemically-driven enzymatic reactions and its application to middle molecule drug discoveryPrincipal Investigator

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Development of electrode interface for NAD + / NADH redox reaction with high efficiency equivalent to in vivo

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Redox control of bacterial cells using metal porous materialsPrincipal Investigator

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Redox control of disease-related metalloproteins and its application to drug developmentPrincipal Investigator

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Sensitive assay for nucleic acid and protein interactions and its application for nucleic acid medicinesPrincipal Investigator

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Highly efficient and sensitive analysis of multiplex drug metabolism reactionsPrincipal Investigator

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Development of microsome electrode for efficient drugMetabolism assayPrincipal Investigator

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Electrochemically-driven CYP reactions with nanostructured electrode surfacesPrincipal Investigator

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直接電気化学法を用いたCYPのハイスループット薬物代謝活性計測ツールの開発Principal Investigator

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[Journal Article] Efficacy of films of uncapped gold nanoparticle as electrodes for direct electron transfer to redox proteins2024

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[Journal Article] Nanostructured gold thin film electrode derived from surfactant-free gold nanoparticles for enhanced electrocatalysis2023

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[Journal Article] Electrochemical Molecular Conversion of α-Keto Acid to Amino Acid at a Low Overpotential Using a Nanoporous Gold Catalyst2021

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[Journal Article] Nanoporous gold based electrodes for electrochemical studies of human neuroglobin2020

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[Journal Article] Electrochemical Oxidation of Monosaccharides at Nanoporous Gold with Controlled Atomic Surface Orientation and Non-Enzymatic Galactose Sensing2020

Mie Yasuhiro 三重安弘

MIE Yasuhiro 三重安弘