Wada Tsutomu 和田努

… Alternative Names

WADA Tsutomu 和田努

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Researcher Number	00419334
Other IDs
Affiliation (Current)	2025: 富山大学, 学術研究部薬学・和漢系, 講師
Affiliation (based on the past Project Information) *help	2019 – 2024: 富山大学, 学術研究部薬学・和漢系, 講師 2013 – 2018: 富山大学, 大学院医学薬学研究部(薬学), 講師 2014: 富山大学, 大学院医学薬学研究部 (薬学), 講師 2014: 富山大学, 大学院医学薬学研究部(薬学)・病態制御薬理学, 講師 2011 – 2012: 富山大学, 大学院・医学薬学研究部(薬学), 助教 … More 2011 – 2012: 富山大学, 大学院医学薬学研究部(薬学), 助教 2008 – 2010: University of Toyama, 医学薬学研究部(薬学), 助教 2009: University of Toyama, 医学薬学研究部, 助教 2007: University of Toyama, 大学院・医学薬学研究科, 助教 2006: 富山大学, 大学院医学薬学研究部, 助手 Less
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 54040:Metabolism and endocrinology-related / Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Obstetrics and gynecology / Basic Section 54040:Metabolism and endocrinology-related / Basic Section 59040:Nutrition science and health science-related / Environmental physiology (including Physical medicine and Nutritional physiology)
Keywords	Principal Investigator 肥満 / インスリン抵抗性 / 慢性炎症 / 血管新生 / アルドステロン / 糖尿病 / エピゲノム / 内臓脂肪 / リバウンド / 増殖 … More / 分化 / 脂肪組織血管 / 脂肪幹細胞 / ペリサイト / エネルギー代謝 / 脂肪組織 / SDF1 / VEGF / PDGF / エストロゲン受容体 / 制御性Ｔ細胞 / 糖代謝 / エストロゲン / 妊娠糖尿病 / ERa / T細胞 / 代謝 / 性差 / Treg / PDGFR / Insulin resistance / Obesity / PDGFRβ / PDGFレセプターβ / エネルギー消費 / 脂肪組織肥大化 / レニン・アンギオテンシン系 / 炎症 / 視床下部 / ミトコンドリア / ROS / 炎症性サイトカイン / NASH / NAFLD / メタボリックシンドローム / α7ニコチン受容体 / ニコチン / 動脈硬化症 / シグナル伝達 … More Except Principal Investigator 糖代謝 / うつ / インスリン抵抗性 / 糖尿病 / オレキシン / エストロゲン / 嗅覚 / エネルギー代謝 / 脂質代謝 / 慢性炎症 / 閉経 / 日内リズム / ストレス / 視床下部 / 性差 / Siglec-G / SiglecG / 肥満 / 2型糖尿病 / 未病 / 耐糖能異常 / 閉経期 / ホルモン補充療法 / 不安 / 中枢作用 / エストラジオール / Ｔ細胞 / T細胞 / 免疫 / 時計遺伝子 / ERストレス / 肝糖新生 / 不眠 / ホスファターゼ / 食欲 / SHIP2 / リピッドホスファターゼ / 妊娠糖尿病 Less

脂肪組織の可塑性メモリーを規定するエピゲノム制御による肥満リバウンド抑止法の開発Principal Investigator
- Principal Investigator
  
  和田努
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Toyama
Development of a novel treatment for diabetes and depression by promoting olfactory and orexin system
- Principal Investigator
  
  笹岡利安
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  University of Toyama
飽食病態改善のための「嗅覚」刺激を介した飢餓対応型代謝の活用と脂質利用の拡大
- Principal Investigator
  
  恒枝宏史
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of Toyama
Regulatory mechanism of adipose stem cells associated with vascular remodeling in obesityPrincipal Investigator
- Principal Investigator
  
  Wada Tsutomu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  University of Toyama
Preventive and therapeutic significance of CD52 in metabolic diseases with obesity
- Principal Investigator
  
  SASAOKA TOSHIYASU
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  University of Toyama
Mechanism of adipose angiogenesis by the cooperative action of angiogenic factorsPrincipal Investigator
- Principal Investigator
  
  Wada Tsutomu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  University of Toyama
Development of therapeutic strategy against obesity-associated chronic inflammations based on the mechanism involved in sex-specific difference of Treg localization in adipose tissue.Principal Investigator
- Principal Investigator
  
  Wada Tsutomu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  University of Toyama
Impact of the cooperative effect of estrogen and orexin on abnormalities with emotion and metabolism in menopausal mice
- Principal Investigator
  
  Sasaoka Toshiyasu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  University of Toyama
Role of estrogen via the recruitment of Treg in the control of glucose homeostasis in female mice.
- Principal Investigator
  
  TOSHIYASU Sasaoka
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  University of Toyama
Development of a new estrogen replacement therapy based on a central action of a menopausal metabolic disorder and depression
- Principal Investigator
  
  YONEZAWA Rika
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  University of Toyama
Development of therapeutics for diabetes with dysregulation of sleep/wake rhythm and depressive disorders by timed regulation of hypothalamic orexin system
- Principal Investigator
  
  SASAOKA TOSHIYASU
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  University of Toyama
Enhanced PDGF signaling contributes adipose tissue angiogenesis, expansion, and systemic glucose intolerance in obesity.Principal Investigator
- Principal Investigator
  
  WADA Tsutomu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  University of Toyama
Development of a new therapeutics of gestational diabetes by inhibition of the central action of lipid phosphatase
- Principal Investigator
  
  SASAOKA Toshiyasu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  University of Toyama
Impact of obesity-induced dysregulation of renin-angiotensin-aldosterone system in the hypothalamus on the homeostasis of energy metabolism.Principal Investigator
- Principal Investigator
  
  WADA Tsutomu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Toyama
Clarification of the mechanism by which the impairment of intra-hepatic cellular network caused hepatic insulin resistance in mice.Principal Investigator
- Principal Investigator
  
  WADA Tsutomu
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Toyama
インスリンとニコチンによる動脈硬化進展における分子生物学的作用機序の解明Principal Investigator
- Principal Investigator
  
  和田努
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Toyama

[Book] 内分泌・糖尿病・代謝内科2011
- Author(s)
  笹岡利安, 恒枝宏史, 和田　努
- Publisher
  妊娠によるインスリン抵抗性発症機序
- Data Source
  KAKENHI-PROJECT-23659774
[Book] 妊娠によるインスリン抵抗性発症機序. 内分泌・糖尿病・代謝内科2011
- Author(s)
  笹岡利安, 恒枝宏史, 和田努
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-23659774
[Journal Article] Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesity2024
- Author(s)
  Okekawa A, Wada T, Onogi Y, Takeda Y, Miyazawa Y, Sasahara M, Tsuneki H, Sasaoka T.
- Journal Title
  
  Molecular medicine
  
  Volume: 30 Issue: 1 Pages: 21-21
- DOI
  10.1186/s10020-024-00793-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08549, KAKENHI-PROJECT-21H02713, KAKENHI-PROJECT-23K27648
[Journal Article] C-terminal peptide of preproorexin enhances brain-derived neurotrophic factor expression in rat cerebrocortical cells and recognition memory in mice2024
- Author(s)
  Tsuneki Hiroshi、Honda Kosuke、Sekine Yurika、Yahata Koji、Yasue Moeka、Fujishima Masashi、Takeda Ryuta、Wada Tsutomu、Sasaoka Toshiyasu
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 964 Pages: 176306-176306
- DOI
  10.1016/j.ejphar.2023.176306
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24763, KAKENHI-PROJECT-23K27648
[Journal Article] Resting phase-administration of lemborexant ameliorates sleep and glucose tolerance in type 2 diabetic mice2023
- Author(s)
  Tsuneki Hiroshi、Sugiyama Masanori、Sato Kiyofumi、Ito Hisakatsu、Nagai Sanaka、Kon Kanta、Wada Tsutomu、Kobayashi Nao、Okada Takuya、Toyooka Naoki、Kawasaki Masashi、Ito Toshihiro、Otsubo Ryota、Okuzaki Daisuke、Yasui Teruhito、Sasaoka Toshiyasu
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 961 Pages: 176190-176190
- DOI
  10.1016/j.ejphar.2023.176190
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16534, KAKENHI-PROJECT-23K24763, KAKENHI-PROJECT-23K27648, KAKENHI-PROJECT-23K27671
[Journal Article] A transdermal treatment with MC903 ameliorates diet-induced obesity by reducing visceral fat and increasing myofiber thickness and energy consumption in mice.2023
- Author(s)
  Wada T, Miyazawa Y, Ikurumi M, Fuse K, Okekawa A, Onogi Y, Saito S, Tsuneki H, Sasaoka T.
- Journal Title
  
  Nutr Metab (Lond)
  
  Volume: 20 Issue: 1 Pages: 10-10
- DOI
  10.1186/s12986-023-00732-5
- Open Access
- Data Source
  KAKENHI-PROJECT-21K08549
[Journal Article] Inhibition of adipose tissue angiogenesis prevents rebound weight gain after caloric restriction in mice fed a high-fat diet2023
- Author(s)
  Lee HJ, Jin BY, Park MR, Kim NH, Seo KS, Jeong YT, Wada T, Lee JS, Choi SH, Kim DH.
- Journal Title
  
  Life Sciences
  
  Volume: 332 Pages: 122101-122101
- DOI
  10.1016/j.lfs.2023.122101
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08549
[Journal Article] Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity2022
- Author(s)
  Tsuneki Hiroshi、Maeda Takahiro、Takata Shinjiro、Sugiyama Masanori、Otsuka Koyuki、Ishizuka Hinako、Onogi Yasuhiro、Tokai Emi、Koshida Chiaki、Kon Kanta、Takasaki Ichiro、Hamashima Takeru、Sasahara Masakiyo、Rudich Assaf、Koya Daisuke et al.
- Journal Title
  
  Cell Reports
  
  Volume: 41 Issue: 3 Pages: 111497-111497
- DOI
  10.1016/j.celrep.2022.111497
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06574, KAKENHI-PROJECT-22H04918, KAKENHI-PROJECT-21H02713, KAKENHI-PROJECT-20K21773, KAKENHI-PROJECT-21K19287, KAKENHI-PROJECT-21K19704, KAKENHI-PROJECT-23K24763, KAKENHI-PROJECT-21H05036
[Journal Article] Food odor perception promotes systemic lipid utilization2022
- Author(s)
  Tsuneki Hiroshi, Sugiyama Masanori, Ito Toshihiro, Sato Kiyofumi, Matsuda Hiroki, Onishi Kengo, Yubune Koharu, Matsuoka Yukina, Nagai Sanaka, Yamagishi Towa, Maeda Takahiro, Honda Kosuke, Okekawa Akira, Watanabe Shiro, Yaku Keisuke, et al.
- Journal Title
  
  Nature Metabolism
  
  Volume: 4 Issue: 11 Pages: 1514-1531
- DOI
  10.1038/s42255-022-00673-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11593, KAKENHI-PROJECT-20H03554, KAKENHI-PROJECT-21K19704, KAKENHI-PROJECT-23K24762, KAKENHI-PROJECT-23K24763, KAKENHI-PROJECT-22K16387, KAKENHI-PROJECT-20K20655
[Journal Article] Oestrogen receptor α in T cells controls the T cell immune profile and glucose metabolism in mouse models of gestational diabetes mellitus2021
- Author(s)
  Tanaka T, Wada T, Uno K, Ogihara S, Ie H, Okekawa A, Ishikawa A, Ito T, Miyazawa Y, Sameshima A, Onogi Y, Tsuneki H, Sasahara M, Nakashima A, Saito S, Sasaoka T.
- Journal Title
  
  Diabetologia
  
  Volume: in press Issue: 7 Pages: 1660-1673
- DOI
  10.1007/s00125-021-05447-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08997, KAKENHI-PROJECT-19K09750, KAKENHI-PUBLICLY-19H05011, KAKENHI-PROJECT-21H02713
[Journal Article] Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity2020
- Author(s)
  Watanabe E, Wada T, Okekawa A, Kitamura F, Komatsu G, Onogi Y, Yamamoto S, Sasahara M, Kitada M, Koya D, Tsuneki H, Sasaoka T.
- Journal Title
  
  Angiogenesis .
  
  Volume: 23 Issue: 4 Pages: 667-684
- DOI
  10.1007/s10456-020-09738-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21773, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-18K08469
[Journal Article] Estrogen regulates sex-specific localization of regulatory T cells in adipose tissue of obese female mice2020
- Author(s)
  Ishikawa Akari、Wada Tsutomu、Nishimura Sanshiro、Ito Tetsuo、Okekawa Akira、Onogi Yasuhiro、Watanabe Eri、Sameshima Azusa、Tanaka Tomoko、Tsuneki Hiroshi、Saito Shigeru、Sasaoka Toshiyasu
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 4 Pages: e0230885-e0230885
- DOI
  10.1371/journal.pone.0230885
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08469
[Journal Article] Pro-inflammatory macrophages coupled with glycolysis remodel adipose vasculature by producing platelet-derived growth factor-B in obesity2020
- Author(s)
  Onogi Yasuhiro、Wada Tsutomu、Okekawa Akira、Matsuzawa Takatoshi、Watanabe Eri、Ikeda Keisuke、Nakano Minoru、Kitada Munehiro、Koya Daisuke、Tsuneki Hiroshi、Sasaoka Toshiyasu
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 670-670
- DOI
  10.1038/s41598-019-57368-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08469, KAKENHI-PROJECT-17H02941, KAKENHI-PROJECT-20K21773
[Journal Article] Role of Angiogenesis and Chronic Inflammation in Fat Hypertrophy in NASH Pathology2019
- Author(s)
  Wada Tsutomu、Tsuneki Hiroshi、Sasaoka Toshiyasu
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 139 Issue: 9 Pages: 1163-1167
- DOI
  10.1248/yakushi.19-00011-3
- NAID
  130007699407
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2019-09-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08469
[Journal Article] Timed Inhibition of Orexin System by Suvorexant Improved Sleep and Glucose Metabolism in Type 2 Diabetic db/db Mice.2016
- Author(s)
  Tsuneki H, Kon K, Ito H, Yamazaki M, Takahara S, Toyooka N, Ishii Y, Sasahara M, Wada T, Yanagisawa M, Sakurai T, Sasaoka T.
- Journal Title
  
  Endocrinology.
  
  Volume: 157 Issue: 11 Pages: 4146-4157
- DOI
  10.1210/en.2016-1404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-25293093, KAKENHI-PROJECT-26462379, KAKENHI-PROJECT-15K15599, KAKENHI-PROJECT-15K09380, KAKENHI-PROJECT-16K20085
[Journal Article] Nighttime administration of nicotine improves hepatic glucose metabolism via the hypothalamic orexin system in mice.2016
- Author(s)
  Tsuneki H, Nagata T, Fujita M, Kon K, Wu N, Takatsuki M, Yamaguchi K, Wada T, Nishijo H, Yanagisawa M, Sakurai T, Sasaoka T.
- Journal Title
  
  Endocrinology
  
  Volume: 157 Issue: 1 Pages: 195-206
- DOI
  10.1210/en.2015-1488
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09380, KAKENHI-PROJECT-15K12768, KAKENHI-PROJECT-15K15599, KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PUBLICLY-15H01425, KAKENHI-ORGANIZER-15H05935, KAKENHI-PLANNED-15H05942, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-24390056
[Journal Article] Hypothalamic orexin prevents hepatic insulin resistance via daily bidirectional regulation of autonomic nervous system in mice.2015
- Author(s)
  Tsuneki H, Tokai E, Nakamura Y, Takahashi K, Fujita M, Asaoka T, Kon K, Anzawa Y, Wada T, Takasaki I, Kimura K, Inoue H, Yanagisawa M, Sakurai T, Sasaoka T.
- Journal Title
  
  Diabetes
  
  Volume: 64 Issue: 2 Pages: 459-470
- DOI
  10.2337/db14-0695
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390056, KAKENHI-PROJECT-24591317, KAKENHI-PUBLICLY-25126709, KAKENHI-PROJECT-26282022, KAKENHI-PROJECT-26670599
[Journal Article] Orexin regulates glucose homeodynamics with daily rhythm2015
- Author(s)
  Tsuneki H, Wada T, Sasaoka T.
- Journal Title
  
  Orexin and Sleep. Springer International Publishing Switzerland
  
  Volume: 2015 Pages: 381-394
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390056
[Journal Article] Orexin regulates glucose homeodynamics with daily rhythm.2015
- Author(s)
  Tsuneki H, Wada T, Sasaoka T.
- Journal Title
  
  Orexin and Sleep. Springer International Publishing Switzerland
  
  Volume: 2015 Pages: 381-394
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15599
[Journal Article] 閉経肥満モデルマウスを用いた糖脂質代謝とうつ症状に対するエストロゲンの効果．2014
- Author(s)
  鮫島　梓，米澤理可，和田　努，恒枝宏史，笹岡利安，齋藤　滋．
- Journal Title
  
  産婦人科の実際
  
  Volume: 63 Pages: 1006-1008
- Data Source
  KAKENHI-PROJECT-25670697
[Journal Article] Hypothalamic orexin prevents hepatic insulin resistance induced by socialdefeat stress in mice.2013
- Author(s)
  Tsuneki H, Tokai E, Sugawara C, Wada T, Sakurai T, Sasaoka T.
- Journal Title
  
  Neuropeptides.
  
  Volume: (in press) Issue: 3 Pages: 213-219
- DOI
  10.1016/j.npep.2013.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390056, KAKENHI-PROJECT-24591317
[Journal Article] Rational design and synthesis of 4-substituted 2-pyridin-2-ylamides with inhibitory effects on SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2).2013
- Author(s)
  Ichihara Y, Fujimura R, Tsuneki H, Wada T, Okamoto K, Gouda H, Hirono S, Sugimoto K, Matsuya Y, Sasaoka T, Toyooka N.
- Journal Title
  
  Eur J Med Chem.
  
  Volume: 62 Pages: 649-660
- DOI
  10.1016/j.ejmech.2013.01.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659774, KAKENHI-PROJECT-24390056, KAKENHI-PROJECT-24590058
[Journal Article] SH2-containing inositol 5'-phosphatase 2 selectively impairs hypothalamic insulin signalling and regulation of food intake in mice2013
- Author(s)
  Ichihara Y, Wada T, Soeda Y, Ishii Y, Sasahara M, Tsuneki H, Sasaoka T
- Journal Title
  
  J Neuroendocrinol
  
  Volume: 25 Pages: 372-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659774
[Journal Article] SH2-containing inositol 5'-phosphatase 2 (SHIP2) selectively impaired hypothalamic insulin signalling and regulation of food intake in mice.2013
- Author(s)
  Ichihara Y, Wada T, Soeda Y, Ishii Y, Sasahara M, Tsuneki H, Sasaoka T.
- Journal Title
  
  J Neuroendocrinol.
  
  Volume: 25 Issue: 4 Pages: 372-382
- DOI
  10.1111/jne.12014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590444, KAKENHI-PROJECT-23659774, KAKENHI-PROJECT-23790313, KAKENHI-PROJECT-24390056, KAKENHI-PROJECT-25293093
[Journal Article] New insights into metabolic regulation via bifurcated function of estrogen receptor α.2013
- Author(s)
  Wada T, Tsuneki H, Sasaoka T.
- Journal Title
  
  Diabetes
  
  Volume: 62 Issue: 12 Pages: 3996-3998
- DOI
  10.2337/db13-1325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670697
[Journal Article] Rational design and synthesis of 4-substituted 2-pyridin-2-ylamides with inhibitory effects on SH2 domain-containing inositol 5'-phosphatase 2 (SHIP2)2013
- Author(s)
  Ichihara Y, Fujimura R, Tsuneki H, Wada T, Okamoto K, Gouda H, Hirono S, Sugimoto K, Matsuya Y, Sasaoka T, Toyooka N
- Journal Title
  
  Eur J Med Chem.
  
  Volume: 62 Pages: 649-660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659774
[Journal Article] Role of orexin in the central regulation of glucose and energy homeostasis [Review]2012
- Author(s)
  Tsuneki H, Wada T, Sasaoka T.
- Journal Title
  
  Endocr J
  
  Volume: 59 Issue: 5 Pages: 365-374
- DOI
  10.1507/endocrj.EJ12-0030
- NAID
  10030816218
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390056
[Journal Article] Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet2012
- Author(s)
  Yonezawa R, Wada T, Matsumoto N, Morita M, Sawakawa K, Ishii Y, Sasahara M, Tsuneki H, Saito S, Sasaoka T.
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 303 Issue: 4 Pages: 445-456
- DOI
  10.1152/ajpendo.00638.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390108, KAKENHI-PROJECT-23590444, KAKENHI-PROJECT-23659774
[Journal Article] Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet2012
- Author(s)
  Yonezawa R, Wada T, Matsumoto N, Morita M, Sawakawa K, Ishii Y, SasaharaM, Tsuneki H, Saito S, Sasaoka T
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659774
[Journal Article] Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet2012
- Author(s)
  Wada T, Yonezawa R, Matsumoto N, Morita M, Sawakawa K, Ishii Y, Sasahara M, Tsuneki H, Saito S, Sasaoka T.
- Journal Title
  
  Am J Physiol Endocrinol Metab
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790852
[Journal Article] Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet2010
- Author(s)
  Wada T, Kenmochi H, Miyashita Y, Sasaki M, Ojima M, Sasahara M, Koya D, Tsuneki H, Sasaoka T.
- Journal Title
  
  Endocrinology
  
  Volume: 151 Pages: 2040-2049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790852
[Journal Article] Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation, and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet.2010
- Author(s)
  Wada T, Kenmochi H, Miyashita Y, Sasaki M, Ojima M, Sasahara M, Koya D, Tsuneki H, Sasaoka T.
- Journal Title
  
  Endocrinology (in press)
- Data Source
  KAKENHI-PROJECT-20790641
[Journal Article] Spironolactone Improves Glucose and Lipid Metabolism by Ameliorating Hepatic Steatosis and Inflammation and Suppressing Enhanced Gluconeogenesis Induced by High-Fat and High-Fructose Diet2010
- Author(s)
  Wada T, Kenmochi H, MiyashitaY, Sasaki M, Ojima M, Sasahara M, Kova D, Tsuneki H, Sasaoka
- Journal Title
  
  Endocrinology 151
  
  Pages: 2040-2049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790641
[Journal Article] Aldosterone Inhibits Insulin-Induced Glucose Uptake by Degradation of IRS1 and IRS2 via an ROS-Mediated Pathway in 3T3-L1 Adipocytes.2009
- Author(s)
  Wada T, Ohshima S, Fujisawa E, Koya D, Tsuneki H, Sasaoka T
- Journal Title
  
  Endocrinology 150
  
  Pages: 1662-1669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790641
[Journal Article] Aldosterone inhibits insulin -induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3T3-L1 adipocytes.2009
- Author(s)
  Wada T, Ohshima S, Fujisawa E, Koya D, Tsuneki H, Sasaoka T.
- Journal Title
  
  Endocrinology 150
  
  Pages: 1662-9
- Data Source
  KAKENHI-PROJECT-20790641
[Journal Article] Aldosterone Inhibits Insulin-Induced Glucose Uptake by Degradation of IRS1 and IRS2 via an ROS-Mediated Pathway in 3T3-L1 Adipocytes2009
- Author(s)
  Wada T, Ohshima S, Fujisawa E, Koya D, Tsuneki H, Sasaoka T
- Journal Title
  
  Endocrinology 150(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790641
[Journal Article] Chronic nicotine exposure enhances insulin-induced mitogenic signaling via up-regulation of alpha7 nicotinic receptors in isolated rat aortic smooth muscle cells2007
- Author(s)
  Wada T, Naito M, Kenmochi H, Tsuneki H, Sasaoka T
- Journal Title
  
  Endocrinology 148(2)
  
  Pages: 790-799
- Data Source
  KAKENHI-PROJECT-18790615
[Journal Article] Chronic nicotine exposure enhances insulin-induced mitogenic signaling via up-regulation of alpha 7 nicotinic receptors in isolated rat aortic smooth muscle cells2007
- Author(s)
  Wada T, Naito M, Kenmochi H, Tsuneki H, Sasaoka T.
- Journal Title
  
  Endocrinology 148(2)
  
  Pages: 790-799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790615
[Patent] 新規なN-(ピリジン-2-イル)アルカンアミド誘導体およびそれらを有効成分とするSHIP2阻害剤2012
- Inventor(s)
  笹岡利安, 恒枝宏史, 和田努, 豊岡尚樹, 広野修一
- Industrial Property Rights Holder
  笹岡利安, 恒枝宏史, 和田努, 豊岡尚樹, 広野修一
- Acquisition Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23659774
[Patent] 新規なＮ－（ピリジン－２－イル）アルカンアミド誘導体およびそれらを有効成分とするＳＨＩＰ２阻害剤2012
- Inventor(s)
  笹岡利安, 恒枝宏史, 和田努, 豊岡尚樹, 広野修一
- Industrial Property Rights Holder
  笹岡利安, 恒枝宏史, 和田努, 豊岡尚樹, 広野修一
- Industrial Property Rights Type
  特許
- Filing Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] ビタミンDアナログの外用による肥満マウスの病態改善の分子機構2023
- Author(s)
  宮澤佑一朗、和田努、布施健人、恒枝宏史、笹岡利安
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] 視床下部ペリサイトによる肥満進展機構2023
- Author(s)
  和田努、桶川晃、小野木康弘、恒枝宏史、笹岡利安
- Organizer
  第97回日本内分泌学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] 2型糖尿病予防に関わるマウス嗅覚―代謝連係を促進する薬物制御法の解析．2023
- Author(s)
  杉山聖典，恒枝宏史，山岸永和，松田大樹，和田　努，笹岡利安．
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K27648
[Presentation] 肥満病態でのABCD1欠損マクロファージの炎症応答亢進機構2023
- Author(s)
  和田努、桶川晃、太田康秀、渡邊愛理、長谷川颯、小野木康弘、恒枝宏史、笹岡利安
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] 音楽刺激によるマウスの糖代謝改善効果．2023
- Author(s)
  本多功典，恒枝宏史，高森華月，永井真華，和田　努，笹岡利安．
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K27648
[Presentation] ペリサイトPDGF作用による慢性炎症誘導機構がエネルギー代謝調節に与える意義2023
- Author(s)
  桶川晃, 和田努, 小野木康弘 ,竹田優希 ,恒枝宏史, 笹岡利安
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] 食前の食事の匂い認知による脂質利用促進と2型糖尿病の発症予防2023
- Author(s)
  笹岡利安，杉山聖典，和田　努，恒枝宏史
- Organizer
  第66回日本糖尿病学会年次学術集会（シンポジウム）
- Data Source
  KAKENHI-PROJECT-23K24763
[Presentation] PDGFシグナルを介した視床下部慢性炎症がエネルギー代謝調節に与える機序の解析2023
- Author(s)
  和田努、桶川晃、小野木康弘、恒枝宏史、笹岡利安
- Organizer
  第67回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] マクロファージのミトコンドリア呼吸に対するペルオキシソームABCD1欠損の影響2023
- Author(s)
  和田努、桶川晃、太田康秀、小野木康弘、恒枝宏史、笹岡利安
- Organizer
  第96回日本内分泌学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] 嗅覚刺激と破壊により捉えた嗅覚―脂質代謝連係を基盤とした2型糖尿病の防止機構．2023
- Author(s)
  杉山聖典，恒枝宏史，山岸永和，加川栞奈，大西兼悟，湯舟香春，松田大樹，和田　努，笹岡利安．
- Organizer
  第34回分子糖尿病学シンポジウム
- Data Source
  KAKENHI-PROJECT-23K27648
[Presentation] 音楽刺激によるマウスの糖代謝改善効果2023
- Author(s)
  本多功典，恒枝宏史，高森華月，永井真華，和田　努，笹岡利安
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K24763
[Presentation] 食前の食事の匂い認知による脂質利用促進と2型糖尿病の発症予防．2023
- Author(s)
  笹岡利安，杉山聖典，和田　努，恒枝宏史．
- Organizer
  第66回日本糖尿病学会年次学術集会（シンポジウム）
- Data Source
  KAKENHI-PROJECT-23K27648
[Presentation] 2型糖尿病予防に関わるマウス嗅覚―代謝連係を促進する薬物制御法の解析2023
- Author(s)
  杉山聖典，恒枝宏史，山岸永和，松田大樹，和田　努，笹岡利安
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K24763
[Presentation] 視床下部ペリサイトが媒介する肥満早期の病態進展機構2023
- Author(s)
  和田努、桶川晃、小野木康弘、竹田優希、恒枝宏史、笹岡利安
- Organizer
  第41回日本内分泌学会サマーセミナー
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] 嗅覚刺激と破壊により捉えた嗅覚―脂質代謝連係を基盤とした2型糖尿病の防止機構2023
- Author(s)
  杉山聖典，恒枝宏史，山岸永和，加川栞奈，大西兼悟，湯舟香春，松田大樹，和田　努，笹岡利安
- Organizer
  第34回分子糖尿病学シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24763
[Presentation] ストレス負荷マウスのうつ防止における嗅覚系の役割2022
- Author(s)
  永井真華，湯舟香春，和田　努，恒枝宏史，笹岡利安
- Organizer
  日本薬学会北陸支部第134回例会
- Data Source
  KAKENHI-PROJECT-23K24763
[Presentation] Transdermal application of MC903 ameliorated diet-induced obesity by increasing energy expenditure and muscle fiber thickness in mice.2022
- Author(s)
  Miyazawa Y, Wada T, Tsuneki H, Sasaoka T.
- Organizer
  The 19th Japan-Korea Diabetic Nephropathy Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] 肥満病態進展における脂肪組織および視床下部ペリサイトの重要性2022
- Author(s)
  和田努，桶川晃，恒枝宏史，笹岡利安.
- Organizer
  第96回日本糖尿病学会中部地方会
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] 食前の食餌の匂い認知は脂質代謝を促進して2型糖尿病を防止する2022
- Author(s)
  杉山聖典，恒枝宏史，山岸永和，永井真華，湯舟香春，佐藤清史，松田大樹，大西兼悟，和田　努，笹岡利安
- Organizer
  第33回分子糖尿病学シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24763
[Presentation] 肥満病態進展におけるペリサイトPDGF作用によるエネルギー代謝調節機構の解析2022
- Author(s)
  桶川晃，和田努，恒枝宏史，笹岡利安.
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] 肥満病態下での内臓脂肪肥大化に関わる血管新生の新機構の解明2022
- Author(s)
  和田努
- Organizer
  予防薬理学研究所　シンポジウム2022
- Invited
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] 嗅覚系による脂質恒常性の制御と2型糖尿病の防止効果2022
- Author(s)
  杉山聖典，恒枝宏史，湯舟香春，山岸永和，永井真華，佐藤清史，松田樹大，大西兼悟，和田　努，笹岡利安
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K24763
[Presentation] MC903塗布による肥満マウスの病態改善機構の解明．2021
- Author(s)
  宮澤佑一朗，和田　努，王生美沙，布施健人，塩練久史，恒枝宏史，笹岡利安．
- Organizer
  日本薬学会北陸支部第133回例会
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] 肥満病態エネルギー代謝調節機構に対するペリサイトPDGFシグナルの重要性．2021
- Author(s)
  桶川　晃，和田　努，恒枝宏史，笹岡利安．
- Organizer
  日本薬学会北陸支部第133回例会
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] 内臓脂肪組織におけるペリサイトの脱離を介した脂肪肝細胞の増殖・分化メカニズム．2021
- Author(s)
  北村楓花，和田　努，桶川　晃，恒枝宏史，笹岡利安．
- Organizer
  日本薬学会北陸支部第133回例会
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] ペリサイトPDGFシグナルを介した視床下部慢性炎症とエネルギー代謝制御機構2021
- Author(s)
  桶川晃、和田努、北村楓花、小野木康弘、渡邊愛理、富田淳也、恒枝宏史、笹岡利安
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] 内臓脂肪組織におけるペリサイトの脱離を介した脂肪幹細胞の増殖・分化メカニズム2021
- Author(s)
  北村楓花、和田努、桶川晃、恒枝宏史、笹岡利安
- Organizer
  2021年度薬学会北陸支部第133回例会
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] ペリサイトPDGFシグナルを介した視床下部慢性炎症とエネルギー代謝制御機構．2021
- Author(s)
  桶川　晃，和田　努，北村楓花，恒枝宏史，笹岡利安．
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] 肥満病態エネルギー代謝調節機構に対するペリサイトPDGFシグナルの重要性2021
- Author(s)
  桶川晃、和田努、恒枝宏史、笹岡利安
- Organizer
  2021年度薬学会北陸支部第133回例会
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] 炎症細胞による脂肪組織のリモデリング．2021
- Author(s)
  笹岡利安，恒枝宏史，和田　努．
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] 妊娠糖尿病病態におけるT細胞エストロゲン作用の重要性．2021
- Author(s)
  和田　努，田中智子，叶　喬博，恒枝宏史，中島彰俊，齋藤　滋，笹岡利安．
- Organizer
  第94回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] ペリサイトPDGFシグナルを介した視床下部慢性炎症とエネルギー代謝制御機構2021
- Author(s)
  桶川　晃、和田　努、北村　楓花、小野木　康弘、渡邊　愛理、富田　淳也、恒枝　宏史、笹岡　利安
- Organizer
  第64 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] 炎症細胞による脂肪組織リモデリング2021
- Author(s)
  笹岡利安、恒枝宏史、和田努
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08549
[Presentation] 炎症細胞による脂肪組織リモデリング2021
- Author(s)
  笹岡利安、恒枝宏史、和田努
- Organizer
  第64 回日本糖尿病学会年次学術集会シンポジウム
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] 肥満病態における視床下部PDGFシグナルが中枢性エネルギー代謝調節機構に与える影響の解析．2020
- Author(s)
  桶川　晃，和田　努，小野木康弘，稲田健人，渡邊愛理, 小松　剛，北村楓花，恒枝宏史，笹岡利安．
- Organizer
  第63回日本糖尿病学会年次学術集会（Web開催）
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] SDF1による脂肪組織血管新生に関わる細胞間クロストークの制御機構の解明．2020
- Author(s)
  渡邊愛理，和田　努，桶川　晃，北村楓花，小野木康弘, 宮澤佑一朗，恒枝宏史，笹岡利安．
- Organizer
  第63回日本糖尿病学会年次学術集会（Web開催）
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] T細胞のエストロゲン作用消失はTh17増加に伴い妊娠糖尿病病態を示す．2020
- Author(s)
  田中智子，和田　努，宇埜生美恵，荻原沙希，石川明香里，伊藤哲生, 宮澤佑一朗，鮫島　梓，小野木康弘，恒枝宏史，齋藤　滋，笹岡利安．
- Organizer
  第63回日本糖尿病学会年次学術集会（Web開催）
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] 脂肪肝進展におけるペルオキシソームの極長鎖脂肪酸トランスポーターの意義．2020
- Author(s)
  和田　努，長谷川颯，渡辺志朗，守田雅志，恒枝宏史，笹岡利安．
- Organizer
  第63回日本糖尿病学会年次学術集会（Web開催）
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] SDF1による脂肪組織血管新生に関わる細胞間クロストークの制御機構の解明2020
- Author(s)
  渡邊愛理、和田　努、桶川　晃、北村楓花、小野木康弘、宮澤佑一郎、恒枝宏史、笹岡利安
- Organizer
  第63 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] 肥満病態における視床下部PDGFシグナルが中枢性エネルギー代謝調節機構に与える影響の解析2020
- Author(s)
  桶川　晃、和田　努、小野木　康弘、稲田　健人、渡邊　愛理、小松　剛、北村　楓花、恒枝　宏史、笹岡　利安
- Organizer
  第63 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] 肥満病態における中枢性エネルギー代謝調節へのPDGFシグナルの関与2019
- Author(s)
  桶川晃，和田　努，小野木康弘，稲田健人，渡邊愛理，小松剛，北村楓花，恒枝宏史，笹岡利安
- Organizer
  第19回日本内分泌学会北陸支部学術集会
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] Intracellular metabolism-dependent PDGFB induction in inflammatory macrophages contributes adipose tissue expansion with obesity.2019
- Author(s)
  Tsutomu Wada, Yasuhiro Onogi, Akira Okekawa, Takatoshi Matsuzawa, Eri Watanabe, Go Komatsu, Hiroshi Tsuneki, Toshiyasu Sasaoka.
- Organizer
  American Diabetes Association, 79th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] Pro-inflammatory macrophages promote vascular remodeling in white adipose tissue during diet-induced obesity.2019
- Author(s)
  Yasuhiro Onogi, Tsutomu Wada, Hiroshi Tsuneki, Toshiyasu Sasaoka.
- Organizer
  The 17th Japan-Korea Diabetic Nephropathy Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] 内臓脂肪におけるペリサイトの挙動を介した血管新生制御機構の意義2019
- Author(s)
  渡邊愛理、和田　努、小野木康弘、恒枝宏史、笹岡利安
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] 肥満病態における中枢性エネルギー代謝調節へのPDGFシグナルの関与．2019
- Author(s)
  桶川　晃，和田　努，小野木康弘，稲田健人，渡邊愛理，小松　剛，北村楓花，恒枝宏史，笹岡利安．
- Organizer
  第19回日本内分泌学会北陸支部学術集会
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] 肥満病態におけるマクロファージ細胞内代謝プログラム変化依存的なPdgfb発現誘導機構の解析．2019
- Author(s)
  桶川　晃，和田　努，小野木康弘，松澤崇俊，渡邊愛理，小松　剛，恒枝宏史，笹岡利安．
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] 肥満病態におけるペリサイトの動的変化に対するSDF1シグナルの意義．2019
- Author(s)
  渡邊愛理，和田　努，小野木康弘，恒枝宏史，笹岡利安．
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] 肥満病態におけるペリサイトの動的変化に対するSDF1シグナルの意義2019
- Author(s)
  渡邊愛理、和田　努、小野木康弘、恒枝宏史、笹岡利安
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] T細胞ERα欠損が妊娠糖尿病病態におよぼす影響の解析．2019
- Author(s)
  田中智子，和田　努，宇埜生美恵，荻原沙希，石川明香里，伊藤哲生，王生美沙，鮫島　梓，恒枝宏史，齋藤　滋，笹岡利安．
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] Impact of SDF1/CXCR4 signaling on pericyte mobilization during obesity development.2019
- Author(s)
  Eri Watanabe, Tsutomu Wada, Yasuhiro Onogi, Hiroshi Tsuneki, Toshiyasu Sasaoka.
- Organizer
  The 17th Japan-Korea Diabetic Nephropathy Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] 肥満病態におけるペリサイトの動的変化に対するSDF1シグナルの意義2019
- Author(s)
  渡邊愛理，和田努，小野木康弘，恒枝宏史，笹岡利安
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] Intracellular metaboism-dependent PDGE-B induction in inflammatory macrophages contributes to adipose tissue expansion with obesity.2019
- Author(s)
  Wada T, Onogi Y, Okekawa A, Matsuzawa T, Watanabe E, Komatsu G, Tsuneki H, Sasaoka T.
- Organizer
  American Diabetes Association (ADA) 79th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] 肥満マウスの内臓脂肪組織における制御性T細胞局在変化の雄雌差とそのメカニズムの解析．2019
- Author(s)
  石川明香里，和田　努，伊藤哲生，田中智子，宇埜生美恵，西村燦志朗，齋藤　滋，恒枝宏史，笹岡利安．
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] Pro-inflammatory macrophages promote vascular remodeling via PDGF-B signaling in white adipose tissue during obesity.2019
- Author(s)
  Toshiyasu Sasaoka, Yasuhiro Onogi, Hiroshi Tsuneki, Tsutomu Wada.
- Organizer
  Daegu Symposium on Obesity & Diabetes
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] Intracellular metaboism-dependent PDGE-B induction in inflammatory macrophages contributes to adipose tissue expansion with obesity.2019
- Author(s)
  Wada T, Onogi Y, Okekawa A, Matsuzawa T, Watanabe E, Komatsu G, Tsuneki H, Sasaoka T.
- Organizer
  American Diabetes Association (ADA) 79th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08997
[Presentation] 肥満病態におけるマクロファージ細胞内代謝プログラム変化依存的なPdgfb発現誘導機構の解析2019
- Author(s)
  桶川晃，和田努，小野木康弘，松澤崇俊，渡邊愛理，小松剛，恒枝宏史，笹岡利安
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] 肥満病態におけるマクロファージ細胞内代謝プログラム変化依存的なPdgfb発現誘導機構の解析2019
- Author(s)
  桶川晃、和田努、小野木康弘、松澤崇俊、渡邊愛理、小松剛、恒枝宏史、笹岡利安
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] エストロゲンが雌性肥満マウスの脂肪組織における制御性T細胞局在に与える影響2018
- Author(s)
  石川明香里，和田努，伊藤哲生，王生美沙，田中智子，齋藤滋，恒枝宏史，笹岡利安
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15K09410
[Presentation] The Sdf1-Cxcr4 signals regulate adipose tissue expansion by modulating angiogenesis in diet-induced obesity in mice.2018
- Author(s)
  Tsutomu Wada, Eri Watanabe, Yuri Kotera, Yasuhiro Onongi, Hiroshi Tsuneki, Toshiyasu Sasaoka.
- Organizer
  American Diabetes Association, 78th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] Glycolytic activation promotes PDGF-B production in adipose tissue macrophages during obesity development.2018
- Author(s)
  Yasuhiro Onogi, Tsutomu Wada, Takatoshi Matsuzawa, Akira Okekawa, Eri Watanabe, Hiroshi Tsuneki, Toshiyasu Sasaoka.
- Organizer
  American Diabetes Association, 78th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] SDF1によるペリサイトの制御を介した内臓脂肪肥大化機構2018
- Author(s)
  渡邊愛理、和田　努、小野木康弘、長谷川颯、松澤崇俊、桶川　晃、髙田慎治郎、恒枝宏史、笹岡利安
- Organizer
  第30回分子糖尿病学シンポジウム
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] A novel mechanism of adipose-tissue angiogenesis via PDGF-B signaling in fat tissue expansion during obesity.2018
- Author(s)
  Tsutomu Wada, Yasuhiro Onongi, Eri Watanabe, Takatoshi Matsuzawa, Akira Okekawa, Hiroshi Tsuneki, Toshiyasu Sasaoka.
- Organizer
  2018 BK21 Plus International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08469
[Presentation] CD4+T細胞特異的ERa欠損マウスに対する高脂肪食負荷が脂肪組織慢性炎症におよぼす影響2018
- Author(s)
  田中智子，和田努，伊藤哲生，王生美沙，宇埜生美恵，荻原沙季，石川明香里，鮫島梓，恒枝宏史，齋藤滋，笹岡利安
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15K09410
[Presentation] 肥満病態における制御性T細胞の性特異的な脂肪組織局在が糖代謝に及ぼす影響2017
- Author(s)
  和田努，伊藤哲生，王生美沙，宇埜生美恵，鮫島梓，田中智子，齋藤滋，恒枝宏史，笹岡利安
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15K09410
[Presentation] 肥満病態における制御性T 細胞の性特異的な脂肪組織局在が糖代謝に及ぼす影響2017
- Author(s)
  和田努, 伊藤哲生, 王生美沙, 宇埜生美恵, 鮫島梓, 田中智子, 斎藤滋, 恒枝宏史, 笹岡利安．
- Organizer
  第60回日本糖尿病学会年次学術集会
- Place of Presentation
  名古屋
- Year and Date
  2017-05-18
- Data Source
  KAKENHI-PROJECT-15K09410
[Presentation] 制御性T細胞の性特異的な脂肪組織局在が肥満に伴う慢性炎症と糖代謝に及ぼす影響2016
- Author(s)
  王生美沙，和田努，伊藤哲生，宇埜生美恵，恒枝宏史，鮫島梓，斎藤滋，笹岡利安．
- Organizer
  第16回日本内分泌学会北陸支部学術集会
- Place of Presentation
  金沢
- Year and Date
  2016-10-22
- Data Source
  KAKENHI-PROJECT-15K09410
[Presentation] 視床下部オレキシンによる睡眠と糖代謝の連係調節の意義．2016
- Author(s)
  恒枝宏史，和田　努，笹岡利安．
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] 雌性オレキシン欠損マウスが高度肥満および脂肪組織の慢性炎症を呈する機序の解析．2016
- Author(s)
  越田千晶，恒枝宏史，浅岡健広，和田　努，笹岡利安．
- Organizer
  日本薬学会北陸支部第128回例会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] 不眠症治療薬スボレキサントによる視床下部オレキシン系を介した糖代謝改善効果．2016
- Author(s)
  今　寛太，恒枝宏史，和田　努，笹岡利安．
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] 視床下部オレキシンによる睡眠と糖代謝の連係調節の意義．2016
- Author(s)
  恒枝宏史，和田　努，笹岡利安．
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 視床下部オレキシンの「動的」血糖制御を標的とした糖尿病治療の新戦略．2016
- Author(s)
  恒枝宏史，和田　努，笹岡利安．
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] The ameliorating effect of suvorexant, a dual orexin receptor antagonist, on glucose metabolism in type 2 diabetic db/db mice.2016
- Author(s)
  Tsuneki H, Kon K, Wada T, Sasaoka T.
- Organizer
  52nd EASD Annual Meeting
- Place of Presentation
  Munich, Germany
- Year and Date
  2016-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] Effect of the dipeptidyl peptidase-4 inhibitor teneligliptin on glucose metabolism in ovariectomized mice on a high-fat diet.2016
- Author(s)
  Sameshima A, Wada T, Yonezawa R, Sasaoka T, Saito S.
- Organizer
  68th Annual Congress of the Japan Society of Obstetrics and Gynecology
- Place of Presentation
  Tokyo
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K09410
[Presentation] Dual orexin receptor antagonist ameliorates impaired sleep/wake cycle and glucose metabolism in diabetic db/db mice in a treatment-time dependent manner.2016
- Author(s)
  Kon K, Tsuneki H, Wada T, Sasaoka T.
- Organizer
  The 15th Japan-Korea Diabetic Nephropathy Seminar
- Place of Presentation
  Asahikawa
- Year and Date
  2016-10-27
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] 中枢性糖代謝調節機構におけるドパミンD2受容体系の機能的意義の解析．2016
- Author(s)
  恒枝宏史，東海絵美，髙月真由美，大西兼悟，今　寛太，和田　努，笹岡利安．
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] オレキシン受容体拮抗薬による２型糖尿病マウスの睡眠と肝糖代謝の改善効果．2016
- Author(s)
  恒枝宏史，今　寛太，和田　努，笹岡利安．
- Organizer
  第3回肝臓と糖尿病・代謝研究会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] 視床下部オレキシンの「動的」血糖制御を標的とした糖尿病治療の新戦略．2016
- Author(s)
  恒枝宏史，和田　努，笹岡利安．
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 閉経肥満モデルマウスの脂肪組織における免疫担当細胞の経時的変化と糖代謝異常との関連性について2015
- Author(s)
  鮫島梓，和田努，米澤理可，恒枝宏史，笹岡利安，齋藤滋
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜
- Year and Date
  2015-04-09
- Data Source
  KAKENHI-PROJECT-15K09410
[Presentation] 新規不眠症治療薬スボレキサントの時間治療による2型糖尿病マウスの糖代謝改善効果．2015
- Author(s)
  今　寛太，恒枝宏史，和田　努，笹岡利安．
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 新規不眠症治療薬スボレキサントの時間治療による2型糖尿病マウスの糖代謝改善効果．2015
- Author(s)
  今　寛，恒枝宏史，和田　努，笹岡利安．
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] ニコチン作用から見た視床下部オレキシン系の日内リズム調節が高血糖に及ぼすインパクト．2015
- Author(s)
  恒枝宏史，永田貴嗣，藤田樹生，和田　努，笹岡利安．
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] 制御性T細胞の性特異的な脂肪組織局在が肥満に伴う慢性炎症と糖代謝に及ぼす影響2015
- Author(s)
  伊藤哲生，和田努，樫村彩香，王生美沙，恒枝宏史，鮫島梓，齋藤滋，笹岡利安
- Organizer
  日本薬学会北陸支部第127回例会
- Place of Presentation
  富山
- Year and Date
  2015-11-15
- Data Source
  KAKENHI-PROJECT-15K09410
[Presentation] 視床下部オレキシンによる自律神経系と小胞体ストレス応答を介したマウス肝糖産生の調節機構．2015
- Author(s)
  笹岡利安，和田　努，恒枝宏史．
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] ニコチン作用から見た視床下部オレキシン系の日内リズム調節が高血糖に及ぼすインパクト．2015
- Author(s)
  恒枝宏史，永田貴嗣，藤田樹生，和田　努，笹岡利安．
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 視床下部オレキシンによる加齢および肥満病態での脂肪組織機能の防御効果の解析．2015
- Author(s)
  東海絵美，恒枝宏史，浅岡健広，今　寛太，髙橋佳佑，越田千晶，布目幸久，和田　努，笹岡利安．
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] オレキシン系を標的とした生体リズム制御による2型糖尿病マウスの糖代謝改善効果．2015
- Author(s)
  今　寛太，恒枝宏史，東海絵美，永田貴嗣，和田　努，笹岡利安．
- Organizer
  日本薬学会北陸支部第127回例会
- Place of Presentation
  富山
- Year and Date
  2015-11-15
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] Hypothalamic orexin as a chronotherapeutic target for type 2 Diabetes.2015
- Author(s)
  Tsuneki H, Nagata T, Kon K, Wada T, Sasaoka T.
- Organizer
  American Diabetes Association (ADA) 75th Scientific Sessions
- Place of Presentation
  Boston, U.S.A.
- Year and Date
  2015-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] オレキシン系を標的とした生体リズム制御による2型糖尿病マウスの糖代謝改善効果．2015
- Author(s)
  今　寛太，恒枝宏史，東海絵美，永田貴嗣，和田　努，笹岡利安．
- Organizer
  日本薬学会北陸支部第127回例会
- Place of Presentation
  富山
- Year and Date
  2015-11-15
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] 制御性T細胞の性特異的な脂肪組織局在が肥満に伴う慢性炎症と糖代謝に及ぼす影響．2015
- Author(s)
  伊藤哲生，和田　努，樫村彩香，王生美沙，恒枝宏史，鮫島　梓，齋藤　滋，笹岡利安．
- Organizer
  日本薬学会北陸支部第127回例会
- Place of Presentation
  富山
- Year and Date
  2015-11-15
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] 視床下部オレキシンによる自律神経系と小胞体ストレス応答を介したマウス肝糖産生の調節機構．2015
- Author(s)
  笹岡利安，和田　努，恒枝宏史．
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] Hypothalamic orexin as a chronotherapeutic target for type 2 diabetes.2015
- Author(s)
  Tsuneki H, Nagata T, Kon K, Wada T, Sasaoka T.
- Organizer
  American Diabetes Association (ADA) 75th Scientific Sessions
- Place of Presentation
  Boston, U.S.A.
- Year and Date
  2015-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15599
[Presentation] 視床下部オレキシンによる加齢および肥満病態での脂肪組織機能の防御効果の解析．2015
- Author(s)
  東海絵美，恒枝宏史，浅岡健広，今　寛太，髙橋佳佑，越田千晶，布目幸久，和田　努，笹岡利安．
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 2型糖尿病マウスでの視床下部オレキシンによる糖代謝改善効果2014
- Author(s)
  笹岡利安，東海絵美，髙橋佳佑，浅岡健広，和田　努，恒枝宏史
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] Inhibition of PDGF Receptor Improves Insulin Resistance via Reduction of MCP1 Expression in Adipose Tissue of Type 2 Diabetes Mice.2014
- Author(s)
  Onogi Y, Wada T, Kamiya C, Inata K, Ishii Y, Sasahara M, Tsuneki H, Sasaoka T
- Organizer
  American Diabetes Association 74th Scientific Sessions
- Place of Presentation
  サンフランシスコ, USA
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] ニコチン作用から見た視床下部オレキシン神経系を介する糖代謝リズム制御の意義．2014
- Author(s)
  恒枝宏史，永田貴嗣，藤田樹生，和田　努，笹岡利安．
- Organizer
  第26回分子糖尿病学シンポジウム
- Place of Presentation
  高知
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] Orexin regulates glucose metabolism under the control of circadian system.2014
- Author(s)
  Tsuneki H, Wada T, Sasaoka T.
- Organizer
  Tokyo Translational Therapeutics Meeting: Homeodynamics in Clocks, Sleep and Metabolism
- Place of Presentation
  Tokyo
- Year and Date
  2014-09-24
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 肥満に伴う脂肪組織の慢性炎症と糖代謝に対するPDGFシグナルの関与の検討2014
- Author(s)
  神谷知江，和田　努　小野木康弘　稲田健人　山本誠士　石井陽子　笹原正清　恒枝宏史　笹岡利安
- Organizer
  第14回日本内分泌学会北陸支部学術集会
- Place of Presentation
  金沢
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] 閉経肥満モデルマウスのエネルギー代謝，うつ，不安に対するエストロゲン投与効果の検討．2014
- Author(s)
  鮫島　梓，和田　努，澤川香苗，森田真裕子，米澤理可，恒枝宏史，笹岡利安，齋藤　滋．
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-25670697
[Presentation] 脳神経特異的PDGFシグナル遮断による肥満および糖脂質代謝への影響の解明2014
- Author(s)
  稲田健人和田努小野木康弘神谷知江恒枝宏史石井陽子笹原正清笹岡利安
- Organizer
  平成26年度日本薬学会北陸支部総会
- Place of Presentation
  金沢
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] PDGFを介した脂肪組織肥大化およびインスリン抵抗性進展機構の解明2014
- Author(s)
  小野木康弘和田　努神谷知江稲田健人山本誠士石井陽子恒枝宏史笹原正清笹岡利安
- Organizer
  平成26年度日本薬学会北陸支部総会
- Place of Presentation
  金沢
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] Wake-active orexin system prevents hepatic insulin resistance via bidirectional regulation of hepatic glucose production in mice2014
- Author(s)
  Tsuneki H, Tokai E, Takahashi K, Asaoka T, Wada.T, Sasaoka T
- Organizer
  Keystone Symposia: Challenges and Opportunities in Diabetes Research and Treatment
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] Hypothalamic orexin system protects against hepatic insulin resistance induced by chronic social defeat stress in mice2013
- Author(s)
  Sasaoka T, Tokai E, Sugawara C, Wada T, Tsuneki H
- Organizer
  The 36th Naito Conference on Molecular Aspects of Energy Balance and Feeding Behavior
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 血管新生を標的とした新たな肥満・糖代謝障害に対する治療法の開発2013
- Author(s)
  和田努, 小野木康弘，神谷知江
- Organizer
  富山大学コラボフェスタ2013
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] エストロゲン中枢選択的投与の肥満・耐糖能・うつ改善効果に関する検討2013
- Author(s)
  米澤理可，和田　努，森田真裕子，澤川香苗，恒枝宏史，笹岡利安，齋藤　滋
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25670697
[Presentation] Hypothalamic orexin generates the circadian metabolic rhythm for maintaining glucose homeostasis in mice2013
- Author(s)
  Tsuneki H, Tokai E, Wada T, Sasaoka T
- Organizer
  The 36th Naito Conference on Molecular Aspects of Energy Balance and Feeding Behavior
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 血管新生を標的とした新たな肥満・糖代謝障害に対する治療法の開発2013
- Author(s)
  和田努
- Organizer
  富山産学官筋交流会2013
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] 糖代謝に対するPDGFシグナルの関与の解析2013
- Author(s)
  小野木康弘, 和田　努, 神谷知江, 石井陽子, 笹原正清, 恒枝宏史, 笹岡利安
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] 視床下部オレキシンの日内リズム制御による２型糖尿病マウスの肝糖代謝の改善効果2013
- Author(s)
  恒枝宏史，東海絵美，髙橋佳佑，浅岡健広，和田　努，笹岡利安
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 視床下部オレキシンによるうつに伴う糖代謝異常の防御機構の解明2013
- Author(s)
  恒枝宏史，東海絵美，菅原千恵子，和田　努，笹岡利安
- Organizer
  第25回分子糖尿病学シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] オレキシン欠損マウスにおいて血糖値の日内リズムの調節が破綻する機序の解析2013
- Author(s)
  髙橋佳佑，恒枝宏史，東海絵美，藤田樹生，浅岡健広，和田　努，笹岡利安
- Organizer
  日本薬学会北陸支部第125回例会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 閉経肥満モデルマウスにおけるエストロゲン末梢または中枢投与のうつ・不安状態に対する改善効果．2013
- Author(s)
  米澤理可，和田　努，鮫島　梓，笹岡利安，斎藤　滋．
- Organizer
  日本産科婦人科学会第65回学術講演会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25670697
[Presentation] 糖尿病に伴う脳機能障害におけるインスリン作用の役割2013
- Author(s)
  恒枝宏史, 和田　努, 笹岡利安
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] Impact of hypothalamic orexin on hepatic insulin resistance induced by chronic social defeat stress in mice2013
- Author(s)
  Sasaoka T, Wada T, Tsuneki H
- Organizer
  The 12th Japan-Korea Diabetic Nephorpathy Seminar
- Place of Presentation
  Gyeongiu, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 糖尿病に伴う脳機能障害におけるインスリン作用の役割.2013
- Author(s)
  恒枝宏史, 和田努, 笹岡利安
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] 慢性的なうつに伴う糖代謝異常に対する視床下部オレキシン系の役割の解析2013
- Author(s)
  笹岡利安，菅原千恵子，東海絵美，和田　努，恒枝宏史
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] エストロゲンの糖脂質代謝改善作用における中枢及び末梢作用の機能的差異の検討．2012
- Author(s)
  米澤理可, 和田　努, 森田真裕子, 澤川香苗, 松本奈都美, 恒枝宏史, 笹岡利安, 齋藤　滋
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] 閉経肥満モデルマウスにおけるエストロゲンの中枢及び末梢投与が不安とうつに与える影響の検討．2012
- Author(s)
  澤川香苗, 和田　努, 森田真裕子, 米澤理可, 齋藤　滋, 恒枝宏史, 笹岡利安
- Organizer
  第12回日本内分泌学会北陸支部学術集会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] Hypothalamic orexin system regulates daily rhythm of glucose metabolism in the liver of mice2012
- Author(s)
  Tsuneki H, Tokai E, Takahashi K, Nakamura Y, Wada T, Sasaoka T
- Organizer
  Keystone Symposia : Aging and Disease of Ageing
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 脳インスリン抵抗性に伴う脳高次機能障害に対するリピッドホスファターゼSHIP2阻害剤の改善効果の解析2012
- Author(s)
  岡本健太郎, 恒枝宏史, 添田義行, 市原克則, 和田努, 笹岡利安
- Organizer
  日本薬学会北陸支部第124回例会
- Place of Presentation
  金沢
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] 閉経肥満モデルマウスにおけるエストロゲンの中枢及び末梢投与が不安とうつに与える影響の検討2012
- Author(s)
  澤川香苗, 和田努, 森田真裕子, 米澤理可, 齋藤滋, 恒枝宏史, 笹岡利安
- Organizer
  第12回日本内分泌学会北陸支部学術集会
- Place of Presentation
  金沢
- Year and Date
  2012-11-10
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] 新規骨格を有する5’-リピッドホスファターゼSHIP2阻害薬の開発とインスリン抵抗性改善効果の検討．2012
- Author(s)
  市原克則, 和田　努, 岡本健太郎, 藤村遼平, 豊岡尚樹, 合田浩明, 広野修一, 恒枝宏史, 笹岡利安
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] うつによるインスリン抵抗性に対する防御機構としの視床下部オレキシンの役割2012
- Author(s)
  恒枝宏史, 菅原千恵子, 東海絵美, 藤田樹生, 和田努, 笹岡利安
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 糖尿病病態におけるリピッドホスファターゼSHIP2の増加が脳高次機能に関わるBDNF発現に与える影響2012
- Author(s)
  岡本健太郎, 恒枝宏史, 細尾脩史, 市原克則, 和田努, 笹岡利安
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] Central and peripheral estrogen differentially ameliorates impaired glucose metabolism in postmenopausal obese mice model.2012
- Author(s)
  Yonezawa R, Wada T, Morita M, Sawakawa K, Ishii Y, Sasahara M, Tsuneki H, Sasaoka T, Saito S.
- Organizer
  American Diabetes Association (ADA) 72th Scientific Sessions
- Place of Presentation
  Philadelphia, PA, U.S.A.
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] エストロゲンの糖脂質代謝改善作用における中枢及び末梢作用の機能的差異の検討2012
- Author(s)
  米澤理可, 和田努, 森田真裕子, 澤川香苗, 松本奈都美, 恒枝宏史, 笹岡利安, 齋藤滋
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] 視床下部オレキシンの欠損によるマウス肝臓の小胞体ストレス応答機構の障害を介した糖産生調節の異常2012
- Author(s)
  東海絵美, 恒枝宏史, 中村優也, 藤田樹生, 高橋佳佑, 和田努, 笹岡利安
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] エストロゲンの末梢または中枢投与による, 卵巣摘出後高脂肪食負荷マウスの糖脂質代謝とうつ症状に対する改善効果とメカニズムの解析．2012
- Author(s)
  米澤理可, 和田　努, 笹岡利安, 斎藤　滋
- Organizer
  日本産科婦人科学会第64回学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] エストロゲンの末梢または中枢投与が閉経肥満モデルマウスのうつ症状改善に与える影響2012
- Author(s)
  米澤理可, 和田努, 笹岡利安, 鮫島梓, 斎藤滋
- Organizer
  第60回北日本産科婦人科学会総会・学術講演会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] エストロゲン・プロゲステロンによるインスリン抵抗性．2012
- Author(s)
  和田　努
- Organizer
  日本産科婦人科学会第64回学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] 5'-リピッドホスファターゼSHIP2が摂食行動に与える影響の解析と, SHIP2を標的とした新規耐糖能改善薬の開発.2012
- Author(s)
  市原克則, 和田努, 岡本健太郎, 藤村遼平, 豊岡尚樹, 合田浩明, 広野修一, 恒枝宏史, 笹岡利安
- Organizer
  日本薬学会北陸支部第124回例会
- Place of Presentation
  金沢
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] エストロゲンの末梢または中枢投与による, 卵巣摘出後高脂肪食負荷マウスの糖脂質代謝とうつ症状に対する改善効果とメカニズムの解析2012
- Author(s)
  米澤理可, 和田努, 笹岡利安, 斎藤滋.
- Organizer
  日本産科婦人科学会第64回学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] 視床下部オレキシンの糖代謝リズム調節による2型糖尿病マウスの血糖改善効果2012
- Author(s)
  恒枝宏史, 東海絵美, 高橋佳佑, 和田努, 笹岡利安
- Organizer
  第24回分子糖尿病学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 糖尿病病態におけるリピッドホスファターゼSHIP2の増加が脳高次機能に関わるBDNF発現に与える影響．2012
- Author(s)
  岡本健太郎, 恒枝宏史, 細尾脩史, 市原克則, 和田　努, 笹岡利安
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] エストロゲンの末梢または中枢投与が閉経肥満モデルマウスのうつ症状改善に与える影響.2012
- Author(s)
  米澤理可, 和田　努, 笹岡利安, 鮫島　梓, 斎藤　滋
- Organizer
  第60回北日本産科婦人科学会総会・学術講演会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] Hypothalamic orexin deficiency causes age-related insulin resistance viaenhancement of ER stress in the liver of mice2012
- Author(s)
  Sasaoka T, Tokai E, Nakamura Y, Fujita M, Wada T, Tsuneki H
- Organizer
  American Diabetes Association 72th Scientific Sessions
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] Central and peripheral estrogen differentially ameliorates impaired glucose metabolism in postmenopausal obese mice model2012
- Author(s)
  Yonezawa R, Wada T, Morita M, Sawakawa K, Ishii Y, Sasahara M, Tsuneki H, Sasaoka T, Saito S.
- Organizer
  American Diabetes Association (ADA) 72th Scientific Sessions
- Place of Presentation
  Philadelphia, PA, U.S.A.
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] エストロゲン・プロゲステロンによるインスリン抵抗性2012
- Author(s)
  和田努
- Organizer
  日本産科婦人科学会第64回学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] 5’-リピッドホスファターゼSHIP2が摂食行動に与える影響の解析と, SHIP2を標的とした新規耐糖能改善薬の開発.2012
- Author(s)
  市原克則, 和田　努, 岡本健太郎, 藤村遼平, 豊岡尚樹, 合田浩明, 広野修一, 恒枝宏史, 笹岡利安
- Organizer
  日本薬学会北陸支部第124回例会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] Estrogen ameliorates glucose homeostasis by coordinating central and peripheral hormonal actions in a postmenopausal obese model of mice2012
- Author(s)
  Toshiyasu Sasaoka, Rika Yonezawa, Mayuko Morita, Kanae Sawakawa, Hiroshi Tsuneki, Shigeru Saito, Tsutomu Wada
- Organizer
  40th Keystone Symposia, Pathogenesis of Diabetes: Emerging Insights into Molecular Mechanisms
- Place of Presentation
  Santa Fe Community Convention Center, Santa Fe, USA
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] 新規骨格を有する5'-リピッドホスファターゼSHIP2阻害薬の開発とインスリン抵抗性改善効果の検討2012
- Author(s)
  市原克則, 和田努, 岡本健太郎, 藤村遼平, 豊岡尚樹, 合田浩明, 広野修一, 恒枝宏史, 笹岡利安
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] Estrogen ameliorates glucose homeostasis by coordinating central and peripheral hormonal actions in a postmenopausal obese model of mice2012
- Author(s)
  Sasaoka T, Yonezawa R, Morita M, Sawakawa K, Tsuneki H, Saito S, Wada T
- Organizer
  40th Keystone Symposia, Pathogenesis of Diabetes: Emerging Insights into Molecular Mechanisms
- Place of Presentation
  Santa Fe, NM, U.S.A.
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] Blockade of mineralocorticoid receptor improves insulin resistance and steatohepatitis in a novel mouse model of non-alchoholic steatohepatitis(NASH) utilizing liver-specific SREBP1c transgenic mice2011
- Author(s)
  Sasaoka T., Miyashita Y., Sasaki M., Tsuneki H., Wada T.
- Organizer
  American Diabetes Association(ADA) 71st Scientific Sessions
- Place of Presentation
  San Diego, CA, U. S. A
- Data Source
  KAKENHI-PROJECT-22790852
[Presentation] エストロゲンによる中枢性及び末梢性の糖エネルギー代謝改善作用の比較検討2011
- Author(s)
  米澤理可, 和田努, 笹岡利安, 斎藤滋
- Organizer
  第27回日本糖尿病・妊娠学会年次学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] エストロゲンの中枢性および末梢性代謝調節作用の検討2011
- Author(s)
  森田真裕子, 和田努, 米澤理可, 松本奈都美,澤川香苗, 斎藤滋, 恒枝宏史, 笹岡利安.
- Organizer
  第11回日本内分泌学会北陸支部学術集会
- Place of Presentation
  富山
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] エストロゲンの中枢及び末梢投与が全身のエネルギーバランス, 体脂肪分布と糖・脂質代謝に与える影響2011
- Author(s)
  米澤理可, 和田努, 笹岡利安, 斎藤滋.
- Organizer
  第63回日本産科婦人科学会学術講演会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] 新規NASHモデルマウスの作成と、抗アルドステロン薬の治療効果の検討2011
- Author(s)
  佐々木元大,和田努,宮下佑介,石井陽子,笹原正清,恒枝宏史,笹岡利安
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22790852
[Presentation] エストロゲンの中枢及び末梢投与が全身のエネルギーバランス, 体脂肪分布と糖・脂質代謝に与える影響2011
- Author(s)
  米澤理可, 和田　努, 笹岡利安, 斎藤　滋
- Organizer
  第63回日本産科婦人科学会学術講演会
- Place of Presentation
  大阪国際会議場（大阪府）
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] エストロゲンの中枢性および末梢性代謝調節作用の検討2011
- Author(s)
  森田真裕子, 和田　努, 米澤理可, 松本奈都美, 澤川香苗, 斎藤　滋, 恒枝宏史, 笹岡利安
- Organizer
  第11回日本内分泌学会北陸支部学術集会
- Place of Presentation
  富山国際会議場（富山県）
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] Blockade of mineralocorticoid receptor improves insulin resistance and steatohepatitis in a novel mouse model of non-alchoholic steatohepatitis (NASH) utilizing liver-specific SREBP1c transgenic mice2011
- Author(s)
  Sasaoka T, Miyashita Y, Sasaki M, Tsuneki H, Wada T
- Organizer
  American Diabetes Association (ADA) 71^<st> Scientific Sessions
- Place of Presentation
  San Diego, CA, U.S.A.
- Data Source
  KAKENHI-PROJECT-22790852
[Presentation] 特異的SREBP1c過剰発現と脂肪・果糖負荷による脂肪性肝炎:アルドステロン阻害薬の効果と創薬2011
- Author(s)
  笹岡利安, 佐々木元大, 恒枝宏史, 和田努
- Organizer
  第12回Pharmaco-Hematology Symposium
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-22790852
[Presentation] リピッドホスファターゼSHIP2が中枢性エネルギー代謝に与える影響2011
- Author(s)
  市原克則, 和田努, 添田義行, 石井陽子, 笹原正清, 恒枝宏史, 笹岡利安
- Organizer
  第12回Pharmaco-Hematology Symposium
- Place of Presentation
  富山
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] エストロゲンによる中枢性及び末梢性の糖エネルギー代謝改善作用の比較検討2011
- Author(s)
  米澤理可, 和田　努, 笹岡利安, 斎藤　滋
- Organizer
  第27回日本糖尿病・妊娠学会年次学術集会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] Blockade of mineralocorticoid receptor ameliorates glucose metabolism and steatohepatitis in a novel mice model of non-alcoholic steatohepatitis2011
- Author(s)
  Wada T, Tsuneki H, Sasaoka T
- Organizer
  2011 International Conference of Diabetes and Metabolism
- Place of Presentation
  Seoul, Korea(招待講演)
- Data Source
  KAKENHI-PROJECT-22790852
[Presentation] Antagonism of mineralocorticoid receptor ameliorates systemic insulin resistance and steatohepatitis in a novel mouse model of non-alcoholic steatohepatitis (NASH) utilizing liver-specific SREBP1c transgenic mice.2011
- Author(s)
  T.Wada, Y.Miyashita, M.Sasaki, Y.Ishii, M.Sasahara, H.Tsuneki, T.Sasaoka
- Organizer
  Keystone Symposia
- Place of Presentation
  Keystone CO., USA
- Data Source
  KAKENHI-PROJECT-22790852
[Presentation] Blockade of mineralocorticoid receptor ameliorates glucose metabolism and steatohepatitis in a novel mice model of non-alcoholic steatohepatitis2011
- Author(s)
  Wada T., Tsuneki H., Sasaoka T.
- Organizer
  2011 International Conference of Diabetes and Metabolism
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-22790852
[Presentation] リピッドホスファターゼSHIP2が中枢性エネルギー代謝に与える影響2011
- Author(s)
  市原克則, 和田　努, 添田義行, 石井陽子, 笹原正清, 恒枝宏史, 笹岡利安
- Organizer
  第12回Pharmaco-Hematology Symposium
- Place of Presentation
  富山国際会議場（富山県）
- Data Source
  KAKENHI-PROJECT-23659774
[Presentation] エストロゲンの中枢及び末梢投与が全身のエネルギーバランス、体脂肪分布と糖・脂質代謝に与える影響2011
- Author(s)
  米澤理可,和田努,森田真裕子,恒枝宏史,笹岡利安,斎藤滋
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22790852
[Presentation] 高脂質高フルクトース負荷マスのメタボリックシンドローム病態に対する抗アルドステロン薬の改善効果2010
- Author(s)
  呂下佑、和田努、剱持弘樹、佐々木元大、恒枝宏史、笹原正清、笹岡利安
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20790641
[Presentation] Blockade of mineralocorticoid receptor ameliorates glucose and lipid metabolism, steatohepatitis, and hepatic fibrosis in a novel mouse model of non-alcoholic steatohepatitis (NASH) utilizing liver-specific SREBP1c transgenic mice.2010
- Author(s)
  T.Wada, Y.Miyashita, M.Sasaki, Y.Ishii, M.Sasahara, H.Tsuneki, T.Sasaoka
- Organizer
  The 9th JSH Single Topic Conference "NASH 2010"(日本肝臓病学会主催)
- Place of Presentation
  Grand Prince Hotel Takanawa
- Data Source
  KAKENHI-PROJECT-22790852
[Presentation] 高脂質高フルクトース負荷マウスのメタボリックシンドローム病態に対する抗アルドステロン薬の改善効果.2010
- Author(s)
  宮下佑介、和田努、剱持弘樹、佐々木元大、恒枝宏史、笹原正清、笹岡利安
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20790641
[Presentation] 肝特異的SREBP1cトランスジェニックマウスを用いた新規NASHモデルマウスに対する、エプレレノンの改善作用の検討2010
- Author(s)
  和田努、宮下佑介、佐々木元大、石井陽子、笹原正清、恒枝宏史、笹岡利安
- Organizer
  第22回分子糖尿病学シンポジウム
- Place of Presentation
  東京コンファレンスセンター品川
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22790852
[Presentation] Spironolactone improves glucose and lipid metabolism and ameliorates hepatic steatosis induced by high-fat and high-fructose diet2010
- Author(s)
  Wada T, Miyashita Y, Sasaki M , Kenmochi H, Sasahara M, Tsuneki H, Sasaoka T
- Organizer
  American Diabetes Association's 70th Scientific Sessions
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-20790641
[Presentation] Spironolactone improves glucose and lipid metabolism and ameliorates hepatic steatosis induced by high-fat and high-fructose diet.2010
- Author(s)
  Wada T, Miyashita Y, Sasaki M, Kenmochi H, Sasahara M, Tsuneki H, Sasaoka T.
- Organizer
  American Diabetes Association's 70th Scientific Sessions
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-20790641
[Presentation] Spironolactone ameliorates glucose and lipid metabolism by suppressing enhanced gluconeogenesis and hepatic inflammation with fatty liver in mice with diet-induced metabolic syndrome.2009
- Author(s)
  Wada T. Kenmochi H. Miyashita Y. Sasaki M, Tsuneki H, Sasahara M, Sasaoka T.
- Organizer
  The 2nd International Aldosterone Forum in Japan
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-20790641
[Presentation] Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis, inflammation, and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet.2009
- Author(s)
  Wada T, Kenmochi H, Miyashita Y, Sasaki M, Sasahara M, Tsuneki H, Sasaoka T.
- Organizer
  第2回Insulin Resistance in Metabolic Disease Forum
- Place of Presentation
  Tokyo
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20790641
[Presentation] Spironolactone improves glucose and lipid metabolism by amelior ating hepatic steatosis, inflammation, and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet.2009
- Author(s)
  Wada T, Kenmochi H, Miyas hita Y, Sasaki M, Sasahara M, Tsuneki H, Sasaoka T
- Organizer
  第2回 Insulin Resistance in Metabolic Disease Forum
- Place of Presentation
  Tokyo
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20790641
[Presentation] Spironolactone ameliorates glucose and lipid metabolism by supp ressing enhanced gluconeogenesis and hepatic inflammation with fatty liver in mice with diet-induced metabolic syndrome.2009
- Author(s)
  Wada T.Kenmochi H.Miyashita Y.Sasaki M, Tsuneki H, Sasahara M, Sasaoka T.
- Organizer
  The 2nd International Aldosterone Forum in Japan
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-20790641
[Presentation] Novel Mechanisms of Aldosterone-Induced Inhibition on Insulin's Metabolic Signaling in 3T3-L1 Adipocytes2008
- Author(s)
  Sasaoka T, Wada T
- Organizer
  Annual meeting of American diabetes association
- Place of Presentation
  サンフランシスコ、USA
- Year and Date
  2008-06-03
- Data Source
  KAKENHI-PROJECT-20790641
[Presentation] ニコチンは視床下部オレキシン神経系を介してマウス肝糖新生を抑制する．
- Author(s)
  永田貴嗣，恒枝宏史，東海絵美，藤田樹生，山口　薫，和田　努，笹岡利安．
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] The role of PDGF signaling in the adipose tissue inflammation and glucose metabolism in obese mice
- Author(s)
  Tsutomu Wada, Yasuhiro Onogi, Chie Kamiya, Kento Inata, Yoko Ishii, Sasahara Masakiyo, Hiroshi Tsuneki, Toshiyasu Sasaoka
- Organizer
  2015 Keystone Symposia Conference, Diabetes and Metabolic Dysfunction
- Place of Presentation
  Santa Fe, NM, U.S.A
- Year and Date
  2015-01-27 – 2015-02-01
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] エストロゲン投与した閉経肥満モデルマウスの耐糖能異常、うつ・不安の改善効果
- Author(s)
  鮫島　梓，和田努，澤川香苗，森田真裕子，米澤理可，恒枝宏史，笹岡利安，齋藤滋
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25861480
[Presentation] PDGFシグナル遮断がインスリン抵抗性に与える影響の解析
- Author(s)
  小野木康弘　和田　努　神谷知江　稲田健人　山本誠士　石井陽子　笹原正清　恒枝宏史　笹岡利安
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21 – 2015-05-24
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] 肥満に伴う耐糖能障害およびインスリン抵抗性進展における PDGFの関与
- Author(s)
  小野木康弘和田努神谷知江稲田健人石井陽子笹原正清恒枝宏史笹岡利安
- Organizer
  第13回次世代を担う若手ファーマ・バイオフォーラム
- Place of Presentation
  富山
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] 中枢神経系のPDGFシグナルがエネルギー代謝に与える影響
- Author(s)
  和田　努　稲田健人　小野木康弘　神谷知江　石井陽子　笹原正清　恒枝宏史　笹岡利安
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21 – 2015-05-24
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] 2型糖尿病マウスでの視床下部オレキシンによる糖代謝改善効果．
- Author(s)
  笹岡利安，東海絵美，髙橋佳佑，浅岡健広，和田　努，恒枝宏史．
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 視床下部オレキシンによる糖代謝リズム調節を介したインスリン抵抗性の治療戦略．
- Author(s)
  恒枝宏史，和田　努，笹岡利安．
- Organizer
  生体機能と創薬シンポジウム2014
- Place of Presentation
  大阪
- Year and Date
  2014-08-28 – 2014-08-29
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 閉経肥満モデルマウスの脂肪組織における免疫担当細胞の経時的変化と糖代謝異常との関連性について
- Author(s)
  鮫島　梓，和田　努，米澤理可，恒枝宏史，笹岡利安，斎藤　滋．
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜
- Year and Date
  2015-04-09 – 2015-04-12
- Data Source
  KAKENHI-PROJECT-25670697
[Presentation] Effects of ｔeneligliptin on ｇlucose and energy metabolism in a mice model of postmenopausal obesity.
- Author(s)
  Sameshima A, Wada T, Itoh T, Kashimura A, Yonezawa R, Tsuneki H, Sasaoka T, Saito S.
- Organizer
  Ａｍｅｒｉｃａｎ Diabetes Associarion (ADA) 75th Scientific Sessions
- Place of Presentation
  Boston, MA, U.S.A.
- Year and Date
  2015-06-05 – 2015-06-09
- Data Source
  KAKENHI-PROJECT-25670697
[Presentation] Inhibition of PDGF Receptor Improves Insulin Resistance via Reduction of MCP1 Expression in Adipose Tissue of Type 2 Diabetes Mice.
- Author(s)
  Yasuhiro Onogi, Tsutomu Wada,Chie Kamiya, Kento Inata, Yoko Ishii, Sasahara Masakiyo, Hiroshi Tsuneki, Toshiyasu Sasaoka
- Organizer
  American Diabetes Association, 74th scientific sessions
- Place of Presentation
  San Fransisco, CA, U.S.A
- Year and Date
  2014-06-13 – 2014-06-17
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] Blockade of PDGF receptors ameliorates adipocyte dysfunctions and improves glucose metabolisms in diabetic db/db mice.
- Author(s)
  Tsutomu Wada, Yasuhiro Onogi, Hiroshi Tsuneki, Toshiyasu Sasaoka
- Organizer
  The 13th Japan-Korea Diabetic Nephropathy Seminar
- Place of Presentation
  Kanazawa, Japan
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] PDGFシグナルが肥満に伴う脂肪組織の肥大化と糖代謝におよぼす影響
- Author(s)
  和田　努小野木康弘稲田健人丸茂勇輝石井陽子笹原正清恒枝宏史笹岡利安
- Organizer
  第33回日本内分泌学会サマーセミナー
- Place of Presentation
  柳川
- Year and Date
  2015-07-09 – 2015-07-11
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] 視床下部オレキシンによるマウス肝糖新生の概日リズムの調節機構の解析．
- Author(s)
  浅岡健広，恒枝宏史，東海絵美，髙橋佳佑，中村優也，和田　努，笹岡利安．
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] Nicotinic regulation of glucose metabolism via hypothalamic orexin system.
- Author(s)
  Tsuneki H, Wada T, Sasaoka T.
- Organizer
  International Society of Addiction Medicine (ISAM) World Congress in 2014
- Place of Presentation
  Yokohama
- Year and Date
  2014-10-02 – 2014-10-06
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 視床下部オレキシン系の動的血糖制御による抗糖尿病作用．.
- Author(s)
  恒枝宏史，和田　努，笹岡利安．
- Organizer
  日本薬学会第135年会（シンポジウム）
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24390056
[Presentation] 閉経肥満モデルマウスにおけるteneligliptinの糖脂質代謝に対する効果の検討．
- Author(s)
  鮫島　梓，和田　努，伊藤哲生，樫村彩香，米澤理可，笹岡利安，斎藤　滋．
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21 – 2015-05-24
- Data Source
  KAKENHI-PROJECT-25670697
[Presentation] PDGF受容体活性阻害による2型糖尿病マウスのインスリン感受性改善機構
- Author(s)
  小野木康弘　和田努　神谷知江　稲田健人　石井陽子　笹原正清　恒枝宏史　笹岡利安
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591318
[Presentation] Hypothalamic orexin prevents hepatic insulin resistance via bidirectional regulation of autonomic nervous system in mice.
- Author(s)
  Sasaoka T, Tokai E, Takahashi K, Asaoka T, Wada T, Tsuneki H.
- Organizer
  American Diabetes Association (ADA) 74th Scientific Sessions
- Place of Presentation
  San Francisco, CA, U.S.A.
- Year and Date
  2014-06-13 – 2014-06-17
- Data Source
  KAKENHI-PROJECT-24390056

1. SASAOKA Toshiyasu (00272906)

# of Collaborated Projects: 12 results

# of Collaborated Products: 181 results
2. TSUNEKI Hiroshi (20332661)

# of Collaborated Projects: 8 results

# of Collaborated Products: 114 results
3. SASAHARA Masakiyo (20154015)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
4. SAITO Shigeru (30175351)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SAMESHIMA AZUSA (80778465)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. 小野木康弘 (80801761)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
7. ISHII Yoko (00361949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
8. YONEZAWA Rika (70649293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. ISHIKAWA AKARI

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. ITO TETSUO

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. IKURUMI MISA

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. TANAKA TOMOKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. 神谷知江

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
14. 稲田健人

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
15. 斎藤滋

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
16. 伊東久勝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 北田宗弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 古家大祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 柳沢正史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 森寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 高崎一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 夜久圭介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Wada Tsutomu 和田 努

WADA Tsutomu 和田 努

Research Projects

Research Products

Co-Researchers

脂肪組織の可塑性メモリーを規定するエピゲノム制御による肥満リバウンド抑止法の開発Principal Investigator

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Regulatory mechanism of adipose stem cells associated with vascular remodeling in obesityPrincipal Investigator

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Mechanism of adipose angiogenesis by the cooperative action of angiogenic factorsPrincipal Investigator

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Development of therapeutic strategy against obesity-associated chronic inflammations based on the mechanism involved in sex-specific difference of Treg localization in adipose tissue.Principal Investigator

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Enhanced PDGF signaling contributes adipose tissue angiogenesis, expansion, and systemic glucose intolerance in obesity.Principal Investigator

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Impact of obesity-induced dysregulation of renin-angiotensin-aldosterone system in the hypothalamus on the homeostasis of energy metabolism.Principal Investigator

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Wada Tsutomu 和田努

WADA Tsutomu 和田努