Hayashi Hideki 林秀樹

… Alternative Names

林秀樹ハヤシヒデキ

HAYASHI Hideki 林秀樹

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Researcher Number	00419665
Other IDs
Affiliation (Current)	2025: 岐阜薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 岐阜薬科大学, 薬学部, 教授 2014 – 2020: 岐阜薬科大学, 薬学部, 准教授 2013: 静岡県立大学, 薬学部, 講師 2008 – 2011: University of Shizuoka, 薬学部, 講師
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Medical pharmacy / Physical pharmacy / Biological pharmacy
Keywords	Principal Investigator 個別化医療 / メトトレキサート / 関節リウマチ / 血漿中濃度 / トランスポーター / TDM / DNAアプタマー / 血中濃度モニタリング / 個別化薬物療法 / 抗体医薬 … More / 脳転移 / EGFR-TKI / 非小細胞肺がん / 薬物動態 / 非小細胞肺癌 / ABCG2 / 遺伝子多型 / 臨床薬物動態 / afatinib / 生物学的製剤 / 血中薬物濃度 / 臨床薬理 / 葉酸トランスポーター / 遺伝子解析 / 医療・福祉 / 薬剤反応性 / 薬理遺伝学 / 臨床薬理学 / 薬学 / 遺伝薬理学 / オーダーメード医療 … More Except Principal Investigator 抗体医薬 / バイオアナリシス / DNAアプタマー / 小児 / 化学療法 / がん化学療法 / ポラプレジンク / 口内炎 / アプタマー / 電子顕微鏡 / ナファモスタット / オキサリプラチン / 末梢神経障害 / グリコカリックス / 自己免疫疾患 / 抗薬物抗体 / 制吐療法 / 化学療法誘発悪心嘔吐 / 卵巣がん / PARP 阻害薬 / ニラパリブ / オラパリブ / CINV / 嘔吐 / 悪心 / PARP阻害剤 / 粘膜付着フィルム / 携帯型近赤外分光装置 / 抗がん剤 / 粘膜付着性フィルム / 抗体医薬分析 / プロセスアナリシス / 大腸癌 / 高度催吐性リスク / 食道癌 / 胃癌 / 乳癌 / 高度催吐性リスク抗がん薬 / 薬理学 / オランザピン / 制吐対策 / 放射線治療 / 癌 / 多施設共同無作為化比較試験 / 造血幹細胞移植前大量化学療法 / 口腔内適用製剤 / 血液腫瘍 / QOL / 有害事象 / 造血幹細胞移植 / 分析科学 / HPLC / LC/MS/MS / 血中薬物濃度分析 / HPLC分析 / ファージデスプレイ / ファージディスプレイ / エピトープワクチン / 癌治療 / オーダーメイド医療 Less

血管内皮障害に着目した化学療法誘発性末梢神経障害に対する新規予防・治療戦略
- Principal Investigator
  
  鈴木昭夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Gifu University
疾患関連抗体に対する抗イディオタイプDNAアプタマーのファスト＆ファインデザイン
- Principal Investigator
  
  轟木堅一郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  University of Shizuoka
Development of an orally disintegrating films containing polaprezinc for prevention of oral mucositis in pediatric patients with cancer
- Principal Investigator
  
  Suzuki Akio
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Gifu University
Clinical pharmacokinetic analysis of antibody drugs by application of innovative measurement techniques directed to personalized medicinePrincipal Investigator
- Principal Investigator
  
  Hayashi Hideki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Gifu Pharmaceutical University
Development of a Strategic Method for Prevention of Side Effects of Oral Anticancer Agents to Improve Life Prognosis and Quality of Life of Ovarian Cancer Patients
- Principal Investigator
  
  Iihara Hirotoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Gifu Pharmaceutical University
Creation of antibody specific nucleic acid aptamers and their application to bio- process- and clinical analyses
- Principal Investigator
  
  Todoroki Kenichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  University of Shizuoka
Development of strategic pharmaceutical therapy to improve QOL by suppressing brain metastasis and reducing side effects in lung cancer patientsPrincipal Investigator
- Principal Investigator
  
  Hayashi Hideki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Gifu Pharmaceutical University
Prophylactic effect of a novel lozenge containing polaprezinc, a zinc-L-carnosine, against chemotherapy-induced oral mucositis in cancer therapy
- Principal Investigator
  
  Akio Suzuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Gifu University
Efficacy of olanzapine for chemotherapy induced nausea and vomiting and investigation of the mechanism of olanzapine as antiemesis agents
- Principal Investigator
  
  Kobayashi Ryo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Gifu University
Development of innovative clinical analytical methods for next-generation drugs using DNA aptamers as molecular recognition elements
- Principal Investigator
  
  Todoroki Kenichiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
Bioanalytical methods for therapeutic monoclonal antibodies using selective separation technique
- Principal Investigator
  
  Kenichiro Todoroki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Shizuoka
Development of the strategic pharmacotherapy using the genetic polymorphisms and the pharmacokinetics in the rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  Hayashi Hideki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Gifu Pharmaceutical University
  University of Shizuoka
Development the efficacious pharmacotherapy based on PK/PD/PGx analyses in patients with rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  HAYASHI Hideki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Shizuoka
Development and clinical application of antibody epitope peptide vaccines for personalized tumor immunotherapy.
- Principal Investigator
  
  ITOH Kunihiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
Establishment of tailor-made drug therapy that aims at improvement of quality of life in patients with rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  HAYASHI Hideki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Shizuoka

[Journal Article] Development of a liquid chromatography-based versatile bioanalysis for bevacizumab based on pretreatment combining aptamer affinity purification and centrifugal ultrafiltration concentration2023
- Author(s)
  Todoroki Kenichiro、Hamada Daichi、Yamada Tomohiro、Saito Taro、Shimizu Yutaka、Sugiyama Eiji、Mizuno Hajime、Hayashi Hideki、Tsukakoshi Kaori、Ikebukuro Kazunori
- Journal Title
  
  Analytical Sciences
  
  Volume: 39 Issue: 11 Pages: 1805-1811
- DOI
  10.1007/s44211-023-00417-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06550, KAKENHI-ORGANIZER-22H05035, KAKENHI-PLANNED-22H05038
[Journal Article] Efficient screening of anti-idiotype DNA aptamers that bind specifically to trastuzumab for bioanalytical applications2023
- Author(s)
  Todoroki Kenichiro、Tong Jiaxing、Aoki Moe、Kobayashi Nao、Isobe Ryota、Tasaki Hiroyuki、Yamada Tomohiro、Furusho Aogu、Sugiyama Eiji、Mizuno Hajime、Hayashi Hideki、Toyo’oka Toshimasa
- Journal Title
  
  Journal of Pharmaceutical and Biomedical Analysis Open
  
  Volume: 1 Pages: 100006-100006
- DOI
  10.1016/j.jpbao.2023.100006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06550
[Journal Article] Pharmaceutical intervention for adverse events improves quality of life in patients with cancer undergoing outpatient chemotherapy.2022
- Author(s)
  Fujii H, Ueda Y, Hirose C, Ohata K, Sekiya K, Kitahora M, Sadaka S, Yamamoto S, Watanabe D, Kato-Hayashi H, Iihara H, Kobayashi R, Kaburaki M, Matsuhashi N, Takahashi T, Makiyama A, Yoshida K, Suzuki A.
- Journal Title
  
  Journal of Pharmaceutical Health Care and Sciences
  
  Volume: 8 Issue: 1 Pages: 8-8
- DOI
  10.1186/s40780-022-00239-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07152, KAKENHI-PROJECT-20K16081
[Journal Article] Development of a Lateral Flow Assay for Bevacizumab Using an Anti-Idiotype DNA Aptamer as a Capture Molecule2022
- Author(s)
  TODOROKI Kenichiro、ISOBE Ryota、YAMADA Tomohiro、SAITO Taro、SHIMIZU Yutaka、TSUKAKOSHI Kaori、SUGIYAMA Eiji、MIZUNO Hajime、HAYASHI Hideki、IKEBUKURO Kazunori
- Journal Title
  
  CHROMATOGRAPHY
  
  Volume: 43 Issue: 2 Pages: 73-77
- DOI
  10.15583/jpchrom.2022.008
- ISSN
  1342-8284, 1348-3315
- Year and Date
  2022-06-20
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03360, KAKENHI-PROJECT-22K06550, KAKENHI-ORGANIZER-22H05035, KAKENHI-PROJECT-20K07157, KAKENHI-PROJECT-19K15694, KAKENHI-PROJECT-19KK0194, KAKENHI-PLANNED-22H05038
[Journal Article] Impact of First-Line FOLFIRINOX-Induced Peripheral Neuropathy on the Efficacy of Second-Line GnP in Patients with Unresectable Advanced Pancreatic Cancer2022
- Author(s)
  Sadaka S, Iwashita T, Fujii H, Kato-Hayashi H, Ohata K, Uemura S, Shimizu M, Suzuki A
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 19 Pages: 5895-5895
- DOI
  10.3390/jcm11195895
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07152, KAKENHI-PROJECT-20K16081
[Journal Article] Association Between Peripheral Neuropathy Induced by Oxaliplatin at First-line Chemotherapy and Efficacy of Paclitaxel at Second-line Chemotherapy in Patients With Advanced Gastric Cancer2022
- Author(s)
  Fujii H, Sadaka S, Ajisawa K, Okumura N, Makiyama A, Iihara H, Yasufuku I, Ohata K, Kobayashi R, Tanaka Y, Hayashi H, Suzuki A
- Journal Title
  
  Anticancer Resarch
  
  Volume: 42 Issue: 9 Pages: 4581-4588
- DOI
  10.21873/anticanres.15961
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07152, KAKENHI-PROJECT-20K10400, KAKENHI-PROJECT-20K16081
[Journal Article] Comparison of chemotherapy-induced nausea and vomiting between gemcitabine plus nab-paclitaxel combination chemotherapy and gemcitabine monotherapy in patients with advanced pancreatic cancer.2021
- Author(s)
  Ohata K, Fujii H, Sadaka S, Kato-Hayashi H, Iihara H, Kobayashi R, Uemura S, Iwashita T, Shimizu M, Suzuki A.
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 7 Pages: 3643-3648
- DOI
  10.21873/anticanres.15154
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07152, KAKENHI-PROJECT-20K10400, KAKENHI-PROJECT-20K16081
[Journal Article] Anorexia, pain and peripheral neuropathy are associated with a decrease in quality of life in patients with advanced pancreatic cancer receiving outpatient chemotherapy: a retrospective observational study2021
- Author(s)
  Fujii H, Koda M, Sadaka S, Ohata K, Kato-Hayashi H, Iihara H, Kobayashi R, Ishihara T, Uemura S, Iwashita T, Hayashi H, Sugiyama T, Shimizu M, Suzuki A.
- Journal Title
  
  Journal of Pharmaceutical Health Care and Sciences
  
  Volume: 7 Issue: 1 Pages: 27-27
- DOI
  10.1186/s40780-021-00210-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07152, KAKENHI-PROJECT-20K10400, KAKENHI-PROJECT-20K16081
[Journal Article] Fluorescence Bioanalysis of Bevacizumab Using Pre-Column and Post-Column Derivatization – Liquid Chromatography After Immunoaffinity Magnetic Purification2020
- Author(s)
  TODOROKI Kenichiro、NAKANO Tatsuki、HAYASHI Hideki、MIZUNO Hajime、Zhe MIN Jun、TOYO’OKA Toshimasa
- Journal Title
  
  CHROMATOGRAPHY
  
  Volume: 41 Issue: 3 Pages: 115-122
- DOI
  10.15583/jpchrom.2020.014
- NAID
  130007933313
- ISSN
  1342-8284, 1348-3315
- Year and Date
  2020-10-20
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03360
[Journal Article] Polaprezinc for prevention of oral mucositis in patients receiving chemotherapy followed by hematopoietic stem cell transplantation: A multi‐institutional randomized controlled trial2020
- Author(s)
  Kitagawa Junichi、Kobayashi Ryo、Nagata Yasuyuki、Kasahara Senji、Ono Takaaki、Sawada Michio、Ohata Koichi、Kato‐Hayashi Hiroko、Hayashi Hideki、Shimizu Masahito、Itoh Yoshinori、Tsurumi Hisashi、Suzuki Akio
- Journal Title
  
  International Journal of Cancer
  
  Volume: 148 Issue: 6 Pages: 1462-1469
- DOI
  10.1002/ijc.33316
- NAID
  120007165668
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08809, KAKENHI-PROJECT-20K07152
[Journal Article] Real-world data of the association between quality of life using the EuroQol 5 Dimension 5 Level utility value and adverse events for outpatient cancer chemotherapy2020
- Author(s)
  Hirose C, Fujii H, Iihara H, Ishihara M, Nawa-Nishigaki M, Kato-Hayashi H, Ohata K, Kumiko Sekiya K, Kitahora M, Matsuhashi N, Takahashi T, Okuda K, Naruse M, Ishihara T, Sugiyama T, Yoshida K, Suzuki A
- Journal Title
  
  Supportive Care in Cancer
  
  Volume: - Issue: 12 Pages: 5943-5952
- DOI
  10.1007/s00520-020-05443-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08440, KAKENHI-PROJECT-20K07152
[Journal Article] Effects of Pharmacokinetics-related Genetic Polymorphisms on the Side Effect Profile of Afatinib in Patients with Non-Small Cell Lung Cancer.2019
- Author(s)
  43.Hayashi H., Iihara H., Hirose C., Fukuda Y., Kitahora M., Kaito D., Yanase K., Endo J., Ohno Y., Suzuki A., Sugiyama T.
- Journal Title
  
  Lung Cancer
  
  Volume: 134 Pages: 1-6
- DOI
  10.1016/j.lungcan.2019.05.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08416
[Journal Article] Anti-Idiotype DNA Aptamer Affinity Purification?High-Temperature Reversed-Phase Liquid Chromatography: A Simple, Accurate, and Selective Bioanalysis of Bevacizumab2019
- Author(s)
  Yamada Tomohiro、Saito Taro、Shimizu Yutaka、Tsukakoshi Kaori、Hayashi Hideki、Mizuno Hajime、Tsuji Daiki、Yamamoto Keisuke、Itoh Kunihiko、Toyo’oka Toshimasa、Ikebukuro Kazunori、Todoroki Kenichiro
- Journal Title
  
  Molecules
  
  Volume: 24 Issue: 5 Pages: 857-857
- DOI
  10.3390/molecules24050857
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08200
[Journal Article] High-Throughput Bioanalysis of Bevacizumab in Human Plasma Based on Enzyme-Linked Aptamer Assay Using Anti-Idiotype DNA Aptamer2019
- Author(s)
  Yamada Tomohiro、Saito Taro、Hill Yoshia、Shimizu Yutaka、Tsukakoshi Kaori、Mizuno Hajime、Hayashi Hideki、Ikebukuro Kazunori、Toyo’oka Toshimasa、Todoroki Kenichiro
- Journal Title
  
  Analytical Chemistry
  
  Volume: 91 Issue: 4 Pages: 3125-3130
- DOI
  10.1021/acs.analchem.8b05725
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08200
[Journal Article] High-Temperature Reversed-Phase LC Separation of Heavy and Light Chain Fragments of Therapeutic Monoclonal Antibodies and Antibody-Drug Conjugate Produced by Chemical Reduction2019
- Author(s)
  SOTOMATSU Sae、YAMADA Tomohiro、MIZUNO Hajime、HAYASHI Hideki、TOYO’OKA Toshimasa、TODOROKI Kenichiro
- Journal Title
  
  CHROMATOGRAPHY
  
  Volume: 40 Issue: 3 Pages: 99-104
- DOI
  10.15583/jpchrom.2019.013
- NAID
  130007741846
- ISSN
  1342-8284, 1348-3315
- Year and Date
  2019-10-20
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03360
[Journal Article] Simultaneous and rapid determination of gefitinib, erlotinib and afatinib plasma levels using liquid chromatography/tandem mass spectrometry in patients with non-small-cell lung cancer2016
- Author(s)
  Hideki Hayashi, Yutaro Kita, Hirotoshi Iihara, Koumei Yanase, Yasushi Ohno, Chiemi Hirose, Maya Yamada, Kenichiro Todoroki, Kiyoyuki Kitaichi, Shinya Minatoguchi, Yoshinori Itoh, Tadashi Sugiyama
- Journal Title
  
  Biomedical Chromatography
  
  Volume: 30 Issue: 7 Pages: 1150-1154
- DOI
  10.1002/bmc.3642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08200
[Journal Article] Bioanalysis of bevacizumab and infliximab by high-temperature reversed-phase liquid chromatography with fluorescence detection after immunoaffinity magnetic purification2016
- Author(s)
  K. Todoroki, T. Nakano, Y. Eda, K. Ohyama, H. Hayashi , D. Tsuji, J.Z. Min, K. Inoue, N. Iwamoto, A. Kawakami, Y. Ueki, K. Itoh, T. Toyo'oka
- Journal Title
  
  Anal. Chim. Acta
  
  Volume: 916 Pages: 112-119
- DOI
  10.1016/j.aca.2016.02.029
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460040, KAKENHI-PROJECT-16K08200, KAKENHI-PROJECT-16K19605
[Journal Article] Reduced folate carrier 1 gene expression levels are correlated with methotrexate efficacy in Japanese patients with rheumatoid arthritis.2015
- Author(s)
  Tazoe Y, Hayashi H, Tsuboi S, Shioura T, Matsuyama T, Yamada H, Hirai K, Tsuji D, Inoue K, Sugiyama T, Itoh K
- Journal Title
  
  Drug Metab. Pharmacokinet.
  
  Volume: in press Issue: 3 Pages: 227-230
- DOI
  10.1016/j.dmpk.2015.02.001
- NAID
  50014429955
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460192
[Journal Article] Simultaneous microdetermination of bosentan, ambrisentan, sildenafil, and tadalafil in plasma using liquid chromatography/tandem mass spectrometry for pediatric patients with pulmonary arterial hypertension.2014
- Author(s)
  Y. Yokoyama, M. Tomatsuri, H. Hayashi, K. Hirai, Y. Ono, Y. Yamada, K. Todoroki, T. Toyo’oka, H. Yamada, K. Itoh
- Journal Title
  
  J. Pharm. Biomed. Anal.
  
  Volume: 89 Pages: 227-232
- DOI
  10.1016/j.jpba.2013.11.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460040
[Journal Article] An artifact derived from a pseudogene led to the discovery of microRNA binding site polymorphism in the 3'-untranslated region of the human dihydrofolate reductase gene2012
- Author(s)
  Hayashi H, Tazoe Y, Horino M, Fujimaki-Katoh C, Tsuboi S, Matsuyama T, Kosuge K, Yamada H, Tsuji D, Inoue K, Itoh K
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume: 27 Pages: 263-267
- NAID
  130004463234
- Data Source
  KAKENHI-PROJECT-22790164
[Journal Article] An Artifact Derived from a Pseudogene Led to the Discovery of MicroRNA Binding Site Polymorphism in the 3′-Untranslated Region of the Human Dihydrofolate Reductase Gene2012
- Author(s)
  Hideki HAYASHI, et al
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 27 Issue: 2 Pages: 263-267
- DOI
  10.2133/dmpk.DMPK-11-NT-092
- NAID
  130004463234
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790164
[Journal Article] 薬効モニタリングの実践-162011
- Author(s)
  林秀樹, 伊藤邦彦
- Journal Title
  
  関節リウマチ
  
  Volume: 62 Pages: 126-131
- Data Source
  KAKENHI-PROJECT-22790164
[Journal Article] Dihydrofolate reductase gene intronic 19-bp deletion polymorphisms in a Japanese population2010
- Author(s)
  Hayashi H, Horino M, Morishita M, Tazoe Y, Tsuboi S, Matsuyama T, Kosuge K, Yamada H, Tsuji D, Inoue K, Itoh K
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume: 25 Pages: 516-518
- NAID
  10027583938
- Data Source
  KAKENHI-PROJECT-22790164
[Journal Article] Dihydrofolate reductase gene intronic 19-bp deletion polymorphisms in a Japanese population2010
- Author(s)
  Hayashi H, Horino M, Morishita M, Tazoe Y, Tsuboi S, Matsuyama T, Kosuge K, Yamada H, Tsuji D, Inoue K, Itoh K
- Journal Title
  
  Drug Metab.Pharmacokinet. (in press)
- NAID
  10027583938
- Data Source
  KAKENHI-PROJECT-20790140
[Journal Article] Generation of a recombinant single chain variable fragment(scFv) targeting 5-methyl-2'-deoxcytidine.2010
- Author(s)
  Ohshima, M., Tadakuma, T., Hayashi, H., Inoue, K., Itoh, K.
- Journal Title
  
  J.Biochem. 147
  
  Pages: 135-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590063
[Journal Article] Generation of AcGFP-labeled single chain Fv against 5-methyl-2'-deoxycytidine from a hyperimmunized mouse using phage display technology.2010
- Author(s)
  Ohshima, M., Inoue, K., Hayashi, H., Tsuji, D., Mizugaki, M., Itoh, K.
- Journal Title
  
  Prot.Eng.Des.Select. 23
  
  Pages: 881-888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590063
[Journal Article] Plasma total homocysteine level and methylenetetrahydrofolate reductase 677C>T genetic polymorphism in Japanese patients with rheumatoid arthritis2009
- Author(s)
  Fujimaki C, Hayashi H, Tsuboi S, Matsuyama T, Kosuge K, Yamada H, Inoue K, Itoh K
- Journal Title
  
  Biomarkers 14
  
  Pages: 49-54
- Data Source
  KAKENHI-PROJECT-20790140
[Journal Article] Antibody epitope peptides as potential inducers of IgG antibodies against CD98 oncoprotein.2009
- Author(s)
  Itoh, K., Ohshima, M., Sonobe, M., Saito, M., Yoshida, A., Hayashi, H., Inoue, K., Masuko, T.
- Journal Title
  
  Cancer Sci 100
  
  Pages: 126-131
- NAID
  10025141602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590063
[Journal Article] Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis.2009
- Author(s)
  Hideki Hayashi, et al.
- Journal Title
  
  Journal of Clinical Pharmacy and Therapeutics 34
  
  Pages: 355-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790140
[Journal Article] Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis.2009
- Author(s)
  Hayashi H, Fujimaki C, Daimon T, Tsuboi S, Matsuyama T, Itoh K
- Journal Title
  
  J. Clin. Pharm. Ther. 34
  
  Pages: 355-361
- Data Source
  KAKENHI-PROJECT-20790140
[Journal Article] Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis2009
- Author(s)
  Hideki Hayashi, et.al.
- Journal Title
  
  Journal of Clinical Pharmacy and Therapeutics (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790140
[Presentation] 抗 trastuzumab DNA アプタマーの高親和性化に向けたアプタマーダイマーの設計とその評価2023
- Author(s)
  青木萌恵、北條泰成、小林直央、古庄仰、杉山栄二、轟木堅一郎
- Organizer
  第35回バイオメディカル分析化学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06550
[Presentation] 抗体医薬の血中濃度分析のためのEnzyme-Linked Aptamer Assay法の開発2023
- Author(s)
  平山知歩、久野絢菜、田﨑裕之、小林直央、古庄仰、杉山栄二、轟木堅一郎
- Organizer
  新アミノ酸分析研究会第13回学術講演会
- Data Source
  KAKENHI-PROJECT-22K06550
[Presentation] Rituximabに対する高親和性DNAアプタマーの探索とその結合能評価および血清中薬物濃度測定2023
- Author(s)
  小林直央、北條泰成、田﨑裕之、平山知歩、後藤厚子、古庄仰、杉山栄二、轟木堅一郎
- Organizer
  新アミノ酸分析研究会第13回学術講演会
- Data Source
  KAKENHI-PROJECT-22K06550
[Presentation] DNAアプタマーを捕捉分子とするnivolumabのバイオアナリシス法の開発2023
- Author(s)
  田﨑裕之、古庄仰、杉山栄二、水野初、鈴木昭夫、林秀樹、轟木堅一郎
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K06550
[Presentation] Rituximabに対する高親和性アプタマーの探索とその結合能評価および血清中薬物濃度測定2023
- Author(s)
  小林直央、北條泰成、田﨑裕之、平山知歩、後藤厚子、古庄仰、杉山栄二、轟木堅一郎
- Organizer
  第20回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Data Source
  KAKENHI-PROJECT-22K06550
[Presentation] DNA アプタマーを捕捉分子とするNivolumab の血中薬物濃度分析法の開発2022
- Author(s)
  田﨑裕之、古庄仰、杉山栄二、水野初、鈴木昭夫、林秀樹、轟木堅一郎
- Organizer
  新アミノ酸分析研究会第12回学術講演会（東京）
- Data Source
  KAKENHI-PROJECT-22K06550
[Presentation] 小児患者における造血幹細胞移植前化学療法に伴う口内炎に対するポラプレジンクの予防効果2022
- Author(s)
  船渡三結、小関道夫、伊藤拓哉、石原正志、小林亮、大西秀典、田原耕平、鈴木昭夫
- Organizer
  第50回日本小児神経外科学会
- Data Source
  KAKENHI-PROJECT-20K07152
[Presentation] 抗体医薬に対する抗イディオタイプ DNA アプタマーの効率的な探索と評価2022
- Author(s)
  小林直央、北條泰成、後藤厚子、杉山栄二、水野初、轟木堅一郎
- Organizer
  第29回クロマトグラフィーシンポジウム（石垣、ハイブリッド開催）
- Data Source
  KAKENHI-PROJECT-22K06550
[Presentation] 抗体医薬Trastuzumabに対する高親和性DNAアプタマーの探索研究2022
- Author(s)
  青木萌恵、磯部亮太、小林直央、北條泰成、古庄仰、杉山栄二、轟木堅一郎
- Organizer
  第53 回中部化学関係学協会支部連合秋季大会（愛知、オンライン開催）
- Data Source
  KAKENHI-PROJECT-22K06550
[Presentation] 抗体医薬に対する高親和性DNA アプタマーの探索過程の効率化と結合様式の解明2022
- Author(s)
  小林直央、北條泰成、後藤厚子、杉山栄二、水野初、轟木堅一郎
- Organizer
  「分析中部・ゆめ21」若手交流会・第22回高山フォーラム（静岡、オンライン開催）
- Data Source
  KAKENHI-PROJECT-22K06550
[Presentation] 抗体医薬Rituximabに対する高親和性抗イディオタイプDNAアプタマーの探索2022
- Author(s)
  磯部亮太、小林直央、北條泰成、古庄仰、杉山栄二、水野初、轟木堅一郎
- Organizer
  第34回バイオメディカル分析科学シンポジウム（船橋）
- Data Source
  KAKENHI-PROJECT-22K06550
[Presentation] 免疫チェックポイント阻害薬ニボルマブの血漿中薬物濃度モニタリング2022
- Author(s)
  南場千智、山崎瑞季、古溝奈緒、飯原大稔、鈴木昭夫、林　秀樹
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2022
- Data Source
  KAKENHI-PROJECT-20K07157
[Presentation] 胃癌患者における1次治療オキサリプラチンの末梢神経障害が2次治療タキサン系抗がん剤の有効性および安全性に与える影響2022
- Author(s)
  左髙史織, 藤井宏典, 味澤香苗, 奥村直樹, 牧山明資, 飯原大稔, 安福至, 大畑紘一, 小林亮, 田中善宏, 林秀樹, 鈴木昭夫
- Organizer
  第32回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-20K07152
[Presentation] 水晶振動子マイクロバランス法による抗体医薬に対する抗イディオタイプDNA アプタマーの結合定数測定2022
- Author(s)
  磯部亮太、小林直央、青木萌恵、古庄仰、杉山栄二、水野初、轟木堅一郎
- Organizer
  新アミノ酸分析研究会第12回学術講演会（東京）
- Data Source
  KAKENHI-PROJECT-22K06550
[Presentation] DNAアプタマーを利用した抗体医薬の製造現場における簡易 FRET定量法の開発2022
- Author(s)
  轟木堅一郎、山田朋宏、齋藤太郎、清水裕、塚越かおり、水野初、林秀樹、豊岡利正、池袋一典
- Organizer
  第82回分析化学討論会（茨城）
- Data Source
  KAKENHI-PROJECT-22K06550
[Presentation] テモゾロミド併用放射線療法における5-HT3受容体拮抗薬の連日内服の忍容性に関する検討2021
- Author(s)
  關谷久美子，原田紗希，後藤咲香，藤井宏典，飯原大稔，小林亮，鈴木昭夫
- Organizer
  第31回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-20K07152
[Presentation] 抗体医薬に対する高親和性DNAアプタマーの効率的な探索法の構築2021
- Author(s)
  小林直央
- Organizer
  第52回中部化学関係学協会支部連合秋季大会
- Data Source
  KAKENHI-PROJECT-19H03360
[Presentation] 外来がん化学療法における支持療法への薬学的介入による患者QOLの網羅的定量評価2021
- Author(s)
  上田祐稀乃，藤井宏典，廣瀬智恵美，大畑紘一，飯原大稔，鏑木美帆，松橋延壽，高橋孝夫，吉田和弘，鈴木昭夫，林秀樹
- Organizer
  第31回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-20K07152
[Presentation] 3種抗体医薬に対する高親和性DNAアプタマーの効率的な探索とその評価2021
- Author(s)
  小林直央
- Organizer
  新アミノ酸分析研究会第11回学術講演会
- Data Source
  KAKENHI-PROJECT-19H03360
[Presentation] アプタマーアフィニティー精製とtrypsin消化－LC-MS/MSを組み合わせた抗体医薬の簡便かつ高選択的な血中薬物濃度定量法の開発2019
- Author(s)
  外松沙依、山田朋宏、齋藤太郎、清水裕、杉山栄二、水野初、塚越かおり、林秀樹、豊岡利正、池袋一典、轟木堅一郎
- Organizer
  第30回クロマトグラフィー科学会議（京都）
- Data Source
  KAKENHI-PROJECT-19H03360
[Presentation] Relationship between severity of adverse events of afatinib and its pharmacokinetics and pharmacogenomics for EGFR mutation-positive non-small cell lung cancer2019
- Author(s)
  Gomyo T, Iihara H, Hayashi H, Endo J, Ito F, Yanase K, Kaito D, Sasaki Y, Sakai C, Hirose C, Fukuda Y, Sugiyama T, Suzuki A, Ohno Y
- Organizer
  American Thoracic Society International Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08416
[Presentation] アファチニブの抗腫瘍効果と副作用に対する血漿中濃度と動態関連遺伝子多型の影響2019
- Author(s)
  林　秀樹, 飯原　大稔, 廣瀬　智恵美, 福田　純久, 上森　将吾, 北洞　美佳, 垣内　大蔵, 柳瀬　恒明, 遠渡　純輝, 大野　康, 鈴木　昭夫, 杉山　正
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08416
[Presentation] Aptamer affinity purification - trypsin digestion LC-MS/MS: A simple and selective bioanalysis of bevacizumab2019
- Author(s)
  Sae Sotomatsu, Tomohiro Yamada, Taro Saito, Yutaka Shimizu, Eiji Sugiyama, Hajime Mizuno, Kaori Tsukakoshi, Hideki Hayashi, Toshimasa Toyo’oka, Kazunori Ikebukuro, Kenichiro Todoroki
- Organizer
  The 49th International Symposium on High Performance Liquid Phase Separations and Related Techniques (Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03360
[Presentation] 抗がん薬分解能を有する新規可視光応答型被膜の開発2019
- Author(s)
  小林　亮，山田　紘嗣，山田　悠人，鈴村　祐司，鈴木　昭夫
- Organizer
  日本薬学会第139 年会
- Data Source
  KAKENHI-PROJECT-17K08441
[Presentation] EGFRチロシンキナーゼ阻害薬アファチニブの血漿中濃度と動態関連遺伝子多型が薬効と副作用重症度に及ぼす影響2019
- Author(s)
  上森将吾、林秀樹、飯原大稔、福田純久、廣瀬智恵美、北洞美佳、垣内太蔵、柳瀬恒明、遠藤純輝、大野康、鈴木昭夫、杉山正
- Organizer
  医療薬学フォーラム2019/第27回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08416
[Presentation] 非小細胞肺癌治療薬アファチニブの抗腫瘍効果と副作用重症度に対する血漿中濃度と関連遺伝子多型の影響2019
- Author(s)
  上森　将吾, 林　秀樹, 飯原　大稔, 福田　純久, 廣瀬　智恵美, 北洞　美佳, 垣内　大蔵, 柳瀬　恒明, 遠渡　純輝, 大野　康, 鈴木　昭夫, 杉山　正
- Organizer
  第4回日本臨床薬理学会東海・北陸地方会
- Data Source
  KAKENHI-PROJECT-17K08416
[Presentation] イホスファミド併用化学療法施行患者における中枢神経毒性の発現状況の検討2019
- Author(s)
  志水　真也，林　祐一，西田　承平，小林　亮，鈴木　昭夫
- Organizer
  日本薬学会第139 年会
- Data Source
  KAKENHI-PROJECT-17K08441
[Presentation] Effect of Afatinib plasma levels and pharmacokinetics-related genetic polymorphisms on the degree of side effects in2018
- Author(s)
  Yoshihisa Fukuda, Hideki Hayashi, Hirotoshi Iihara, Naoki Mizusaki, Chiemi Hirose, Komei Yanase, Yasushi Ohno, Yoshinori
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08416
[Presentation] 末梢血幹細胞移植において目標数のCD34陽性細胞が採取できない要因に関する検討2018
- Author(s)
  大畑紘一, 加藤寛子, 山内智世, 小林亮, 松本拓郎, 中村信彦, 北川順一, 兼村信宏, 清水雅仁, 鈴木昭夫
- Organizer
  第28回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-17K08440
[Presentation] 乳癌アントラサイクリン/シクロホスファミド併用療法に対する制吐対策としてのオランザピンの有効性の評価．2018
- Author(s)
  小林亮, 名和美奈子, 廣瀬智恵美, 松岡梨恵, 鈴木昭夫, 森龍太郎, 二村学, 杉山正, 吉田和弘, 伊藤善規.
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08440
[Presentation] 非小細胞肺癌患者におけるEGFRチロシンキナーゼ阻害薬の血漿中濃度と動態関連遺伝子多型が副作用重症度に及ぼす影響2018
- Author(s)
  福田純久、林　秀樹、飯原大稔、水崎直樹、廣瀬智恵美、柳瀬恒明、大野　康、伊藤善規、杉山　正、小原道子
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08416
[Presentation] Effect of Afatinib plasma levels and pharmacokinetics-related genetic polymorphisms on the degree of side effects in patients with non-small cell lung cancer2018
- Author(s)
  Yoshihisa Fukuda, Hideki Hayashi, Hirotoshi Iihara, Naoki Mizusaki, Chiemi Hirose, Komei Yanase, Yasushi Ohno, Yoshinori Itoh, Tadashi Sugiyama, Michiko Obara
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08416
[Presentation] 肺がん化学療法施行時の悪心・嘔吐に対する六君子湯の効果2018
- Author(s)
  廣瀬智恵美, 飯原大稔, 舟口祝彦, 舟口祝彦, 遠渡純輝, 伊藤文隆, 柳瀬恒明, 垣内大蔵, 佐々木優佳, 五明岳展, 酒井千鶴, 小林亮, 佐藤幸奈, 木野村元彦, 大野康, 川崎雅規, 鈴木昭夫
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会
- Data Source
  KAKENHI-PROJECT-17K08441
[Presentation] 乳癌アントラサイクリン/シクロホスファミド併用療法に対する制吐対策としてのオランザピンの有効性の評価2018
- Author(s)
  小林亮, 名和美奈子, 廣瀬智恵美, 松岡梨恵, 鈴木昭夫, 森龍太郎, 二村学, 杉山正, 吉田和弘, 伊藤善規
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08441
[Presentation] オピオイド鎮痛剤による便秘予防薬として有用な緩下剤処方に関する検討2017
- Author(s)
  星野良, 石原正志, 船渡三結, 小林　亮, 鈴木昭夫, 伊藤善規
- Organizer
  第25回医療薬学フォーラム2017
- Data Source
  KAKENHI-PROJECT-17K08441
[Presentation] Bioanalysis of therapeutic monoclonal antibodies based on affinity purification and high-temperature HPLC2017
- Author(s)
  Kenichiro Todoroki, Tatsuki Nakano, Hideki Hayashi, Hajime Mizuno, Jun Zhe Min, Toshimasa
- Organizer
  46th International Symposium on High Performance Liquid Phase Separations and Related Techniques
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08200
[Presentation] 悪心のコントロール不良を及ぼすシスプラチンの用量決定に関する検討2017
- Author(s)
  藤井宏典, 飯原大稔, 石原正志, 小林亮, 鈴木昭夫, 田中善弘, 山口和也, 吉田和弘, 伊藤善規
- Organizer
  第27回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-17K08441
[Presentation] 悪心のコントロール不良を及ぼすシスプラチンの用量決定に関する検討2017
- Author(s)
  藤井宏典、飯原大稔、石原正志、小林亮、鈴木昭夫、田中善弘、山口和也、吉田和弘、伊藤善規.
- Organizer
  第27回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-17K08440
[Presentation] 小児患者における造血幹細胞移植前化学療法に伴う口内炎に対するポラプレジンクの予防効果2017
- Author(s)
  船渡三結、石原正志、小林亮、鈴木昭夫、小関道夫、深尾敏幸、伊藤善規.
- Organizer
  日本緩和医療薬学会2017
- Data Source
  KAKENHI-PROJECT-17K08440
[Presentation] Sensitive bioanalysis of bevacizumab using pre-column and post-column fluorescence derivatization - liquid chromatography after immunoaffinity magnetic purification2016
- Author(s)
  Kenichiro Todoroki, Tatsuki Nakano, Hideki Hayashi, Hajime Mizuno, Jun Zhe Min, Toshimasa Toyo’oka
- Organizer
  XVII International Symposium on Luminescence Spectrometry
- Place of Presentation
  Taipei Medical University
- Invited
- Data Source
  KAKENHI-PROJECT-16K08200
[Presentation] アフィニティー精製-高温逆相LCによる抗体医薬の血中薬物濃度分析法開発2016
- Author(s)
  轟木堅一郎、中野達基、山田朋宏、林秀樹、大山要、水野初、閔俊哲、豊岡利正
- Organizer
  第29回バイオメディカル分析科学シンポジウム
- Place of Presentation
  京都大学
- Invited
- Data Source
  KAKENHI-PROJECT-16K08200
[Presentation] 薬物動態インフォメーションを活用した臨床薬理研究の動向と新展開　関節リウマチ治療薬メトトレキサートの薬効に影響する葉酸トランスポーターの遺伝子多型2015
- Author(s)
  林秀樹, 田添唯, 坪井声示, 松山耐至, 杉山正, 伊藤邦彦
- Organizer
  日本薬物動態学会第30回年会
- Place of Presentation
  タワーホール船堀(東京）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-25460192
[Presentation] 抗体医薬のTDM　―関節リウマチ患者における検討―2014
- Author(s)
  大鹿雄美，山宮翔，田添　唯，林秀樹，松山耐至，坪井声示，轟木堅一郎，井上和幸，辻　大樹，山田　浩，豊岡利正，伊藤邦彦
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県熊本市
- Data Source
  KAKENHI-PROJECT-25460192
[Presentation] Separation behavior characterization of therapeutic monoclonal antibody preparations by high-temperature reversed-phase LC using wide pore core-shell column.2013
- Author(s)
  Kenichiro Todoroki, Atsuko Nakane, Koji Toyoda, Yuki Sato, Hideki Hayashi, Tsutomu Kai, Jun Zhe Min, Koichi Inoue, Shinobu Kudoh, Kunihiko Itoh, Toshimasa Toyo’oka:
- Organizer
  The 40th International Symposium on High Performance Liquid Phase Separations and Related Techniques
- Place of Presentation
  Tasmania
- Data Source
  KAKENHI-PROJECT-25460040
[Presentation] 抗イディオタイプリコンビナントFabを用いた生物学的製剤の血中濃度測定法の構築2013
- Author(s)
  大鹿雄美、林秀樹、轟木堅一郎、坪井声示、松山耐至、辻大樹、井上和幸、豊岡利正、山田浩、伊藤邦彦
- Organizer
  第59回　日本薬学会東海支部総会・大会
- Place of Presentation
  名城大学薬学部
- Data Source
  KAKENHI-PROJECT-25460040
[Presentation] トリプシン消化LC/MS/MSによる抗体医薬品の血漿薬物濃度分析法の開発2013
- Author(s)
  豊田耕司、轟木堅一郎、林秀樹、坪井声示、松山耐至、閔俊哲、井之上浩一、伊藤邦彦、豊岡利正
- Organizer
  第24回クロマトグラフィー科学会議
- Place of Presentation
  東京大学
- Data Source
  KAKENHI-PROJECT-25460040
[Presentation] トリプシン消化LC/MS/MSによる血漿中抗体医薬品の分析2013
- Author(s)
  豊田耕司、轟木堅一郎、林秀樹、坪井声示、松山耐至、閔俊哲、井之上浩一、伊藤邦彦、豊岡利正
- Organizer
  新アミノ酸分析研究会第3回学術講演会
- Place of Presentation
  東京大学
- Data Source
  KAKENHI-PROJECT-25460040
[Presentation] 抗リウマチ薬メトトレキサートの赤血球中濃度と遺伝子多型の関連性の検討2012
- Author(s)
  田添唯, 林秀樹, 森下茉莉子, 坪井声示, 松山耐至, 荒井輝久, 大鹿雄美, 小菅和仁, 山田浩, 辻大樹, 井上和幸, 伊藤邦彦
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-22790164
[Presentation] 関節リウマチ治療薬メトトレキサートの薬効予測遺伝子マーカー2011
- Author(s)
  田添唯、林秀樹, ほか
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Year and Date
  2011-05-29
- Data Source
  KAKENHI-PROJECT-22790164
[Presentation] MALTリンパ腫患者から単離したヒト型リコンビナントFabの認識する抗原の解析(第3報):免疫沈降法を用いたrFab認識抗原の同定2011
- Author(s)
  成島悠太, 近藤雅紘, 板野太亮, 井上和幸, 林秀樹, 辻大樹, 正木康史, 益子高, 伊藤邦彦
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590063
[Presentation] ジヒドロ葉酸還元酵素の遺伝子多型がメトトレキサートの抗リウマチ効果に及ぼす影響の検討2011
- Author(s)
  田添唯、堀野雅人、林秀樹、森下茉莉子、坪井声示、松山耐至、小菅和仁、山田浩、辻大樹、井上和幸、伊藤邦彦
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22790164
[Presentation] 関節リウマチでのメトトレキサート療法に影響する遺伝的因子の解析2011
- Author(s)
  田添唯、林秀樹, ほか
- Organizer
  第21回日本医療薬学会年会
- Place of Presentation
  神戸
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-22790164
[Presentation] ジヒドロ葉酸還元酵素の遺伝子多型がメトトレキサートの抗リウマチ効果に及ぼす影響の検討2011
- Author(s)
  田添唯、林秀樹, ほか
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡(静岡市)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22790164
[Presentation] 抗リウマチ薬メトトレキサートの効果不十分症例における遺伝的因子の解析2011
- Author(s)
  田添唯、林秀樹、森下茉莉子、坪井声示、松山耐至、荒井輝久、大鹿雄美、小菅和仁、山田浩、辻大樹、井上和幸、伊藤邦彦
- Organizer
  第32回日本臨床薬理学会年会
- Place of Presentation
  浜松
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-22790164
[Presentation] MALTリンパ腫患者から単離したヒト型リコンビナントFabの認識する抗原の解析(第2報):ミモトープペプチド免疫で誘導したリコンビナントFabの性状解析2010
- Author(s)
  江上蓉子, 大島幹弘, 成島悠太, 井上和幸, 林秀樹, 辻大樹, 正木康史, 益子高, 伊藤邦彦
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20590063
[Presentation] 関節リウマチにおけるmethotrexate反応性予測因子としてのdihydrofolate reductase遺伝子多型2010
- Author(s)
  堀野雅人, 林秀樹, 藤巻千裕, 森下茉莉子, 小菅和仁, 坪井声示, 松山耐至, 山田浩, 井上和幸, 辻大樹, 伊藤邦彦
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20790140
[Presentation] 鎖状ミモトープペプチドによる効率的抗腫瘍免疫誘導の検討2010
- Author(s)
  近藤雅紘, 齋藤美沙, 大島幹弘, 出口和輝, 林秀樹, 井上和幸, 辻大樹, 益子高, 伊藤邦彦
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20590063
[Presentation] 関節リウマチにおけるmethotrexate反応性予測因子としてのdihydrofolate reductase2010
- Author(s)
  堀野雅人、林秀樹, 他
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山県桃太郎アリーナ
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20790140
[Presentation] 関節リウマチ患者におけるテーラーメイド薬物療法の実現を目指した遺伝子多型解析研究2009
- Author(s)
  藤巻千裕, 林秀樹, 松山耐至, 坪井声示, 井上和幸, 伊藤邦彦
- Organizer
  第23回静岡県病院薬剤師会学術大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20790140
[Presentation] 抗体エピトープペプチドによる抗腫瘍免疫誘導:ミモトーフペプチドを用いた検討2009
- Author(s)
  齋藤美沙, 大島幹弘, 近藤雅紘, 井上和幸, 林秀樹, 益子高, 伊藤邦彦
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590063
[Presentation] MALTリンパ腫患者から単離したヒト型リコンビナントFabの認識する抗原の解析:ファージディスプレイランダムぺプチドライブラリーを用いた検討2009
- Author(s)
  江上蓉子, 大島幹弘, 吉田晃, 井上和幸, 林秀樹, 正木康史, 益子高, 伊藤邦彦
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590063
[Presentation] 関節リウマチ患者における赤血球中メトトレキサート活性体濃度測定2009
- Author(s)
  林秀樹, 藤巻千裕, 松山耐至, 坪井声示, 井上和幸, 伊藤邦彦
- Organizer
  第23回静岡県病院薬剤師会学術大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20790140
[Presentation] ホモシステインと疾患活動性～関節リウマチにおける検討～ハイライト集収載2008
- Author(s)
  林秀樹, 藤巻千裕, 坪井声示, 松山耐至, 原田直人, 伊藤邦彦
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20790140
[Presentation] 抗腫瘍抗体エピトープペプチドにより誘導された抗体レパートリーのクローニングと機能および構造解析2008
- Author(s)
  大島幹弘, 薗部桃代, 斎藤美沙, 吉田晃, 林秀樹, 益子高, 伊藤邦彦
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590063
[Presentation] 関節リウマチ患者における血球中メトトレキサート濃度測定2008
- Author(s)
  林秀樹, 藤巻千裕, 坪井声示, 松山耐至, 井上和幸, 伊藤邦彦
- Organizer
  第54回日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790140
[Presentation] 関節リウマチ患者におけるメトトレキサートの薬効に影響する遺伝的因子2008
- Author(s)
  林秀樹、他
- Organizer
  第18回日本医療薬学会年会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2008-09-30
- Data Source
  KAKENHI-PROJECT-20790140
[Presentation] 関節リウマチ患者におけるメトトレキサートの薬効に影響する遺伝的因子2008
- Author(s)
  林秀樹, 藤巻千裕, 坪井声示, 大門貴志, 松山耐至, 井上和幸, 伊藤邦彦
- Organizer
  第18回日本医療薬学会年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20790140

1. Kenichiro Todoroki (70341451)

# of Collaborated Projects: 7 results

# of Collaborated Products: 29 results
2. Akio Suzuki (80775148)

# of Collaborated Projects: 7 results

# of Collaborated Products: 21 results
3. Kobayashi Ryo (50555662)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
4. ITOH Kunihiko (90221770)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
5. Iihara Hirotoshi (40775095)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 橋本博 (40336590)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 池袋一典 (70251494)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. MASAKI Yasufumi (40238895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. YAMADA Hiroshi (40265252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 杉山正 (30453054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 田原耕平 (30454325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 大野康 (00334938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 平井啓太 (30740203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 安部正和 (90644063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 岡田英志 (30402176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 富田弘之 (50509510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TAZOE Yui

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. TSUBOI Seiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. MATSUYAMA Taiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
20. ONO Takaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hayashi Hideki 林 秀樹

林 秀樹 ハヤシ ヒデキ

HAYASHI Hideki 林 秀樹

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Clinical pharmacokinetic analysis of antibody drugs by application of innovative measurement techniques directed to personalized medicinePrincipal Investigator

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Development of strategic pharmaceutical therapy to improve QOL by suppressing brain metastasis and reducing side effects in lung cancer patientsPrincipal Investigator

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Development of the strategic pharmacotherapy using the genetic polymorphisms and the pharmacokinetics in the rheumatoid arthritisPrincipal Investigator

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Development the efficacious pharmacotherapy based on PK/PD/PGx analyses in patients with rheumatoid arthritisPrincipal Investigator

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Hayashi Hideki 林秀樹

林秀樹ハヤシヒデキ

HAYASHI Hideki 林秀樹