Irita Jun 入田純

… Alternative Names

IRITA Jun 入田純

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Researcher Number	00423442
Affiliation (based on the past Project Information) *help	2016: 愛媛大学, 医学部附属病院, 講師 2014: 愛媛大学, 医学部附属病院, 講師(病院教員) 2012 – 2013: 愛媛大学, 医学部附属病院, 助教 2012: 愛媛大学, 医学部附属病院, 講師 2012: 愛媛大学, 医学部附属病院, 講師(病院教員) … More 2011: 愛媛大学, 医学部附属病院, 医員 2009: Ehime University, 医学部附属病院, 医員 2008 – 2009: Ehime University, 医学部・附属病院, 医員 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / Cardiovascular medicine Except Principal Investigator Cardiovascular medicine / Kidney internal medicine
Keywords	Principal Investigator オステオポンチン / オステオポンチンノックアウト / プラーク破裂 / 動脈硬化 / N-Halfオステオポンチン / トロンビン切断型オステオポンチン / 急性腎障害 / 炎症 / 酸化ストレス / 腎線維化 / アルドステロン … More Except Principal Investigator … More オステオポンチン / 血栓症 / osteopontin / thrombin cleaved / アテローム血栓性脳梗塞 / 腎尿細管細胞 / フイブロネクチン / タイプIコラーゲン / 慢性腎臓病 / インターロイキン18 / 尿細管細胞 / 高血圧 / 腎線維化 / アルドステロン / Interleukin-18 Less

Usefulness of plasma thrombin-cleaved osteopontin (N-half OPN) level on diagnosis of thrombotic disease
- Principal Investigator
  
  Higaki Jitsuo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Ehime University
Ｎ－Ｈａｌｆオステオポンチンを介した動脈硬化プラーク破裂機構の解明と新規治療戦略Principal Investigator
- Principal Investigator
  
  入田純
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Ehime University
The role of thrombin cleaved osteopontin in ischemic reperfusion renal injury modelsPrincipal Investigator
- Principal Investigator
  
  IRITA Jun
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Ehime University
Roles of interleukin-18 and osteopontin in renal fibrosis
- Principal Investigator
  
  OKURA Takafumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Ehime University
The role of osteopontin in aldosterone-induced renal fibrosisPrincipal Investigator
- Principal Investigator
  
  IRITA Jun
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Ehime University

All 2015 2014 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Carotid hemodynamics is associated with monocyte count determined by serum homocysteine level in patients with essential hypertension2015
- Author(s)
  Jotoku M, Okura T, Miyoshi KI, Irita J, Nagao T, Kukida M, Tanino A, Kudo K, Enomoto D, Pei Z, Higaki J
- Journal Title
  
  Clin Exp Hypertens
  
  Volume: 1 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461112
[Journal Article] Hyperhomocysteinemia is one of the risk factors associated with cerebrovascular stiffness in hypertensive patients, especially elderly males2014
- Author(s)
  Okura T, Miyoshi K, Irita J, Enomoto D, Nagao T, Kukida M, Tanino A, Kudo K, Pei Z, Higaki J
- Journal Title
  
  Sci Rep
  
  Volume: 53 Issue: 1 Pages: 1-5
- DOI
  10.1038/srep05663
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461112
[Journal Article] Osteopontin plays a critical role in interstitial fibrosis but not glomerular sclerosis in diabetic nephropathy2012
- Author(s)
  Nagao T, Okura T, Irita J, Jotoku M, Enomoto D, Desilva VR, Miyoshi K, Kurata M, Matsui Y, Uede T, Higaki J
- Journal Title
  
  Nephron Extra
  
  Volume: 2 Pages: 87-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790945
[Journal Article] Relationship between Renal Hemodynamics and Urinary Type IV Collagen in Patients with Essential Hypertension2012
- Author(s)
  nomoto D, Okura T, Nagao T, Jotoku M, Irita J, Miyoshi KI, Higaki J
- Journal Title
  
  Clin Exp Hypertens
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790945
[Journal Article] Osteopontin plays a critical role in interstitial fibrosis but not glomerular sclerosis in diabetic nephropathy.2012
- Author(s)
  Nagao T
- Journal Title
  
  Nephron Extra
  
  Volume: 2 Issue: 1 Pages: 87-103
- DOI
  10.1159/000337330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390113, KAKENHI-PROJECT-22590912
[Journal Article] Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney.2011
- Author(s)
  Irita J, Okura T, Jotoku M, NagaoT, Enomoto D, Kurata M, Desilva VR, Miyoshi K, Matsui Y, Uede T, Denhardt DT, Rittiling SR, Higaki J.
- Journal Title
  
  American Journal of Physiology renal physiology
  
  Volume: 301 Issue: 4 Pages: F833-F844
- DOI
  10.1152/ajprenal.00557.2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590912
[Journal Article] Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney2011
- Author(s)
  Irita J, Okura T, Jotoku M, Nagao T, Enomoto D, Kurata M, Desilva VR, Miyoshi KI, Matsui Y, Uede T, Denhardt DT, Rittiling SR, Higaki J
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790945
[Journal Article] Angiotensin II receptor blockade with valsartan decreases plasma osteopontin levels in patients with essential hypertension2011
- Author(s)
  Kurata M, Okura T, Irita J, Enomoto D, Nagao T, Jotoku M, Miyoshi KI, Desilva VR, Higaki J
- Journal Title
  
  J Hum Hypertens
  
  Volume: 25 Pages: 333-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790945
[Journal Article] Renal resistance index is a marker of future renal dysfunction in patients with essential hypertension.2010
- Author(s)
  Okura T, Kurata M, Irita J, Enomoto D, Jotoku M, Nagao T, Koresawa M, Kojima S, Hamano Y, Mashiba S, Miyoshi K, Higaki J.
- Journal Title
  
  J Nephrol. 23
  
  Pages: 175-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790595
[Journal Article] Undercarboxylated Osteocalcin Is a Biomarker of Carotid Calcification in Patients with Essential Hypertension.2010
- Author(s)
  Okura T, Kurata M, Enomoto D, Jotoku M, Nagao T, Desilva VR, Irita J, Miyoshi KI, Higaki J.
- Journal Title
  
  Kidney Blood Press Res. 33
  
  Pages: 66-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790595
[Journal Article] Elevated serum uric acid is an independent predictor for cardiovascular events in patients with severe coronary artery stenosis: subanalysis of the Japanese Coronary Artery Disease (JCAD) Study.2009
- Author(s)
  Okura T, Higaki J, Kurata M, Irita J, Miyoshi K, Yamazaki T, Hayashi D, Kohro T, Nagai R.
- Journal Title
  
  Circ J. 73
  
  Pages: 885-91
- NAID
  10025930303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790595
[Journal Article] Osteopontin in rat renal fibroblasts: functional properties and transcriptional regulation by aldosterone.2008
- Author(s)
  Irita J, Okura T, Kurata M, Miyoshi K, Fukuoka T, Higaki J.
- Journal Title
  
  Hypertension. 51
  
  Pages: 507-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790595
[Presentation] Interleukin-18 Deficiency Protects Against Aldosterone-Induced Interstitial Fibrosis in the Kidney.2011
- Author(s)
  Nagao,T Okura T, Jotoku M, Irita J, Enomoto D, Miyoshi K, Higaki J.
- Organizer
  High Blood Pressure Research 2011 Scientific Sessions
- Place of Presentation
  Orland FL, USA
- Data Source
  KAKENHI-PROJECT-22590912
[Presentation] アルドステロンによる腎線維化におけるIL-18 とオステオポンチンの役割2011
- Author(s)
  長尾知明、大蔵隆文、城徳昌典、榎本大次郎、入田純、三好賢一、檜垣實男
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-22590912
[Presentation] アルドステロンによる尿細管間質線維化発症機序-オステオポンチンと EMT 及び酸化ストレスの関連について2011
- Author(s)
  入田純、大蔵隆文、長尾知明、城徳昌典、榎本大次郎、三好賢一、檜垣實男
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-23790945
[Presentation] アルドステロンによる腎線維化におけるIL-18とオステオポンチンの役割2011
- Author(s)
  長尾知明、大蔵隆文、城徳昌典、榎本大次郎、入田純、三好賢一、檜垣實男
- Organizer
  日本高血庄学会総会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-22590912
[Presentation] Osteopontin Deficiency Attenuates Aldosterone induced Tubulointerstitial Fibrosis, EMT, and Oxidative Stress.2011
- Author(s)
  Jun Irita, Takafumi Okura, Masanori Jotoku, Tomoaki Nagao, Daijiro Enomoto, Ken-ichi Miyoshi, Jitsuo Higaki.
- Organizer
  The 13th China-Japan Joint Hypertension Symposium
- Place of Presentation
  Beijing, China.
- Year and Date
  2011-12-04
- Data Source
  KAKENHI-PROJECT-23790945
[Presentation] Interleukin-18 Deficiency Protects Against Aldosterone-Induced Interstitial Fibrosis in the Kidney2011
- Author(s)
  Tomoaki Nagao, Takafumi Okura, Masanori Jotoku, Jun Irita, Daijiro Enomoto, Ken-ichi Miyoshi, Jitsuo Higaki
- Organizer
  High Blood Pressure Research 2011 Scientific Sessions
- Place of Presentation
  Orland FL, USA
- Data Source
  KAKENHI-PROJECT-22590912
[Presentation] レニン・アンジオテンシン・アルドステロン系とオステオポンチンとの関連2010
- Author(s)
  入田純, 大蔵隆文, 檜垣實男
- Organizer
  第39回日本心脈管作動物質学会シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2010-02-05
- Data Source
  KAKENHI-PROJECT-20790595
[Presentation] アルドステロン誘導腎障害におけるオステオポンチンの役割-OPN KOマウスを用いた検討.2010
- Author(s)
  入田純
- Organizer
  第39回日本心脈管作動物質学会シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2010-02-05
- Data Source
  KAKENHI-PROJECT-20790595
[Presentation] アルドステロンによる腎線維化には、オステオポンチンにより惹起される酸化ストレスが関与する2009
- Author(s)
  入田純, 大蔵隆文, 他6名
- Organizer
  第32回日本高血圧学会総会
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-20790595
[Presentation] アルドステロン誘導腎障害におけるオステオポンチンの役割-OPN KOマウスを用いた検討2009
- Author(s)
  入田純, 大蔵隆文, 他6名
- Organizer
  第59回日本腎蔵学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20790595
[Presentation] アルドステロン誘導腎障害におけるオステオポンチンの役割-OPN KOマウスを用いた検討.2009
- Author(s)
  入田純
- Organizer
  第59回日本腎臓学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20790595
[Presentation] Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress and interstitial fibrosis in the kidney2009
- Author(s)
  Irita J, Okura T, et al, (他6名)
- Organizer
  63rd High Blood Pressure Research Conference 2009
- Place of Presentation
  Chicago, IL, USA.
- Data Source
  KAKENHI-PROJECT-20790595
[Presentation] アルドステロン誘導腎障害におけるオステオポンチンの役割-OPN KOマウスを用いた検討.2009
- Author(s)
  入田純
- Organizer
  第32回日本高血圧学会総会
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-20790595
[Presentation] アルドステロン誘導腎障害におけるオステオポンチンの役割-OPN KOマウスを用いた検討.2009
- Author(s)
  入田純
- Organizer
  63^<rd> High Blood Pressure Reseach Confbrence
- Place of Presentation
  アメリカ合衆国シカゴ
- Data Source
  KAKENHI-PROJECT-20790595
[Presentation] OPN遺伝子及びAOPE遺伝子の両欠損マウスでは頸動脈結紮後の新生内膜形成が抑制される
- Author(s)
  谷野彰子、工藤佳代、裴作為、茎田昌敬、長尾知明、入田純、三好賢一、大蔵隆文、檜垣實男
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-25461133

1. MIYOSHI Ken-ichi (50423439)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. OKURA Takafumi (40260385)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. NAGAO Tomoaki (20512164)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. JHOTOKU Masanori (10452690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. Higaki Jitsuo (70189744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 桧垣実男

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Irita Jun 入田 純

IRITA Jun 入田 純

Research Projects

Research Products

Co-Researchers

Usefulness of plasma thrombin-cleaved osteopontin (N-half OPN) level on diagnosis of thrombotic disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ｎ－Ｈａｌｆオステオポンチンを介した動脈硬化プラーク破裂機構の解明と新規治療戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of thrombin cleaved osteopontin in ischemic reperfusion renal injury modelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of interleukin-18 and osteopontin in renal fibrosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of osteopontin in aldosterone-induced renal fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Carotid hemodynamics is associated with monocyte count determined by serum homocysteine level in patients with essential hypertension2015

Author(s)

Journal Title

Data Source

[Journal Article] Hyperhomocysteinemia is one of the risk factors associated with cerebrovascular stiffness in hypertensive patients, especially elderly males2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Osteopontin plays a critical role in interstitial fibrosis but not glomerular sclerosis in diabetic nephropathy2012

Author(s)

Journal Title

Data Source

[Journal Article] Relationship between Renal Hemodynamics and Urinary Type IV Collagen in Patients with Essential Hypertension2012

Author(s)

Journal Title

Data Source

[Journal Article] Osteopontin plays a critical role in interstitial fibrosis but not glomerular sclerosis in diabetic nephropathy.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney.2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Osteopontin deficiency protects against aldosterone-induced inflammation, oxidative stress, and interstitial fibrosis in the kidney2011

Author(s)

Journal Title

Data Source

[Journal Article] Angiotensin II receptor blockade with valsartan decreases plasma osteopontin levels in patients with essential hypertension2011

Author(s)

Journal Title

Data Source

[Journal Article] Renal resistance index is a marker of future renal dysfunction in patients with essential hypertension.2010

Author(s)

Journal Title

Data Source

[Journal Article] Undercarboxylated Osteocalcin Is a Biomarker of Carotid Calcification in Patients with Essential Hypertension.2010

Author(s)

Journal Title

Data Source

[Journal Article] Elevated serum uric acid is an independent predictor for cardiovascular events in patients with severe coronary artery stenosis: subanalysis of the Japanese Coronary Artery Disease (JCAD) Study.2009

Author(s)

Irita Jun 入田純

IRITA Jun 入田純