Abe Akihiro 安部明弘

… Alternative Names

ABE Akihiro 安部明弘

安部明弘アベアキヒロ

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Researcher Number	00432261
Other IDs
Affiliation (Current)	2025: 藤田医科大学, 医学部, 客員准教授
Affiliation (based on the past Project Information) *help	2018 – 2019: 藤田医科大学, 医学部, 客員准教授 2013 – 2017: 藤田保健衛生大学, 医学部, 客員准教授 2015: 藤田保健衛生大学, 医学部, その他 2010: Nagoya University, 医学(系)研究科(研究院), その他 2008 – 2009: Nagoya University, 大学院・医学系研究科, 特任講師 2006: Nagoya University, Graduate School of Medicine, Designated Assistant Professor, 大学院医学系研究科, 特任講師
Review Section/Research Field	Principal Investigator Hematology Except Principal Investigator Hematology
Keywords	Principal Investigator RNA-seq / G-CSF / 染色体転座 / ゲノム / 遺伝子 / 癌 / 白血病 / 複雑核型 / 融合遺伝子 / 造血器腫瘍 … More / EMID1 / ARID1B / MAML3 / TCF4 / RUNX1 / Leukemia / translocation / fusion gene / HOXA9 / NUP98 / ケモカイン / 細胞遊走 / SDF1 / サイトカイン / ETV6-LPXN / CXCL12 / LPXN / ETV6 / SP分画 / 造血前駆細胞 / 造血幹細胞 / 白血病幹細胞 / イマチニブ / 慢性骨髄性白血病 … More Except Principal Investigator JAK3 / JAK2 / surrogate marker / target therapy / cell signaling / leukemia / チロシンキナーゼ / 発現クローニング法 / FLT3 / キナーゼ阻害剤 / 変異 / ヌクレオフォスミン / 造血器腫瘍 / サロゲートマーカー / 標的治療 / シグナル伝達 / 白血病 Less

Identification and functional analysis of gene aberrations in hematological malignancy with complex chromosomal abnormality using RNA-seq analysisPrincipal Investigator
- Principal Investigator
  
  ABE AKIHIRO
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fujita Health University
Analyses of cytokine responsive signaling of LPXN and enhanced responses caused by ETV6-LPXNPrincipal Investigator
- Principal Investigator
  
  ABE Akihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fujita Health University
慢性骨髄性白血病における分子標的治療後の残存腫瘍の高感度定量法と治療法の開発Principal Investigator
- Principal Investigator
  
  安部明弘
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Analysis of aberrant signal tansduction in hematological malignancy and development of treatment methods.
- Principal Investigator
  
  NAOE Tomoki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University

All 2020 2019 2018 2017 2016 2015 2014 2013 2010 2009 2008 2004 Other

All Journal Article Presentation

[Journal Article] Truncated RUNX1 generated from the　fusion of RUNX1 to antisense GRIK2 via a cryptic chromosome translocation enhances　sensitivity　to granulocyte colony-stimulating factor2020
- Author(s)
  Abe A, Yamamoto Y, Katsumi A, Yamamoto H, Okamoto A, Inaguma Y, Iriyama C, Tokuda M, Okamoto M, Emi N, Tomita A.
- Journal Title
  
  Cytogenetic and Genome Research
  
  Volume: - Issue: 5 Pages: 255-263
- DOI
  10.1159/000508012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09860, KAKENHI-PROJECT-19K08853, KAKENHI-PROJECT-18K15402
[Journal Article] Involvement of MCL1, c-myc, and cyclin D2 protein degradation in ponatinib-induced cytotoxicity against T315I(+) Ph+leukemia cells2020
- Author(s)
  Inoue Chisato、Sobue Sayaka、Kawamoto Yoshiyuki、Nishizawa Yuji、Ichihara Masatoshi、Abe Akihiro、Hayakawa Fumihiko、Suzuki Motoshi、Nozawa Yoshinori、Murate Takahsi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 525 Issue: 4 Pages: 1074-1080
- DOI
  10.1016/j.bbrc.2020.02.165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02698, KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-16K09860
[Journal Article] BCL2 inhibitor ABT-199 and JNK inhibitor SP600125 exhibit synergistic cytotoxicity against imatinib-resistant Ph+ ALL cells.2018
- Author(s)
  Inoue C, Sobue S, Aoyama Y, Mizutani N, Kawamoto Y, Nishizawa Y, Ichihara M, Abe A, Hayakawa F, Suzuki M, Nozawa Y, Murate T.
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: 15 Pages: 69-75
- DOI
  10.1016/j.bbrep.2018.07.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09025, KAKENHI-PROJECT-18H02835, KAKENHI-PROJECT-16K09860, KAKENHI-PROJECT-18H02698, KAKENHI-PROJECT-26290051
[Journal Article] Autologous hematopoietic cell transplantation for acute promyelocytic leukemia in second complete remission: outcomes before and after the introduction of arsenic trioxide2017
- Author(s)
  Yanada M, Yano S, Kanamori H, Gotoh M, Emi N, Watakabe K, Kurokawa M, Nishikawa A, Mori T, Tomita N, Murata M, Hashimoto H, Henzan H, Kanda Y, Sawa M, Kohno A, Atsuta Y, Ichinohe T, Takami A
- Journal Title
  
  Leuk Lymphoma
  
  Volume: 58 Issue: 5 Pages: 1061-1067
- DOI
  10.1080/10428194.2016.1231406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09860, KAKENHI-PROJECT-15K09513
[Journal Article] Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1-RUNX1T1 leukemia with t(8;12;21).2017
- Author(s)
  Abe A, Yamamoto Y, Katsumi A, Okamoto A, Tokuda M, Inaguma Y, Yamamoto K, Yanada M, Kanie T, Tomita A, Akatsuka Y, Okamoto M, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  Int J Hematol.
  
  Volume: - Issue: 2 Pages: 208-212
- DOI
  10.1007/s12185-017-2387-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09451, KAKENHI-PROJECT-15K09473, KAKENHI-PROJECT-17K07182, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-18K15402, KAKENHI-PROJECT-16K09860
[Journal Article] ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9.2016
- Author(s)
  Abe A, Yamamoto Y, Iba S, Kanie T, Okamoto A, Tokuda M, Inaguma Y, Yanada M, Morishima S, Mizuta S, Akatsuka Y, Okamoto M, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  Genes, chromosomes & cancer
  
  Volume: 55(3) Issue: 3 Pages: 242-250
- DOI
  10.1002/gcc.22327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161, KAKENHI-PROJECT-16K09860
[Journal Article] Transcriptional activation of platelet-derived growth factor receptor α and GS homeobox 2 resulting from E26 transformation-specific variant 6 translocation in a case of acute myeloid leukemia with t(4;12)(q12;p13).2016
- Author(s)
  Abe A, Mizuta S, Okamoto A, Yamamoto Y, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  International journal of laboratory hematology
  
  Volume: 38(2) Issue: 2 Pages: 15-18
- DOI
  10.1111/ijlh.12450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161, KAKENHI-PROJECT-16K09860
[Journal Article] Wnt signaling is associated with cell survival in the interaction between acute myeloid leukemia cells and stromal cells2016
- Author(s)
  Niwa Y, Minami Y, Abe A, Hayakawa F, Yamada K, Naoe T
- Journal Title
  
  Leuk Lymphoma
  
  Volume: 57 Issue: 9 Pages: 2192-2194
- DOI
  10.3109/10428194.2015.1124995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09860
[Journal Article] t(11;21)(p14;q22) RUNX1/KIAA1549L2015
- Author(s)
  Abe A
- Journal Title
  
  Atlas Genet Cytogenet Oncol Haematol
  
  Volume: in press
- Open Access
- Data Source
  KAKENHI-PROJECT-25461437
[Journal Article] NUP214-RAC1 and RAC1-COL12A1 Fusion in Complex Variant Translocations Involving Chromosomes 6, 7 and 9 in an Acute Myeloid Leukemia Case with DEK-NUP214.2015
- Author(s)
  Abe A, Yamamoto Y, Iba S, Okamoto A, Tokuda M, Inaguma Y, Yanada M, Morishima S, Kanie T, Tsuzuki M, Akatsuka Y, Mizuta S, Okamoto M, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  Cytogenetic and genome research
  
  Volume: 146(4) Issue: 4 Pages: 279-284
- DOI
  10.1159/000441464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161
[Journal Article] A varicella outbreak in B-cell lymphoma patients receiving rituximab-containing chemotherapy.2014
- Author(s)
  Okamoto A, Abe A, Okamoto M, Kobayashi T, Inaguma Y, Tokuda M, Yanada M, Morishima S, Kanie T, Yamamoto Y, Tsuzuki M, Mizuta S, Akatsuka Y, Yatsuya H, Yoshikawa T, Emi N.
- Journal Title
  
  J Infect Chemother.
  
  Volume: 20 Issue: 12 Pages: 774-777
- DOI
  10.1016/j.jiac.2014.08.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461437
[Journal Article] Molecular Response to Nilotinib in a Patient with Imatinib-intolerant e19a2-positive Chronic Myeloid Leukemia.2014
- Author(s)
  Kajiguchi T, Okuno S, Ohno T, Abe A.
- Journal Title
  
  Intern Med.
  
  Volume: 53 Pages: 2801-2804
- NAID
  130004713289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461437
[Journal Article] Clarifying the Impact of Polycomb Complex Component Disruption in Human Cancers.2014
- Author(s)
  Yamamoto Y, Abe A, Emi N
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 12 Issue: 4 Pages: 479-84
- DOI
  10.1158/1541-7786.mcr-13-0596
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23591410, KAKENHI-PROJECT-25461437
[Journal Article] Injectable Bone Tissue Engineering Using Live Mesenchymal Stem Cells.2013
- Author(s)
  Yamada Y, Nakamura S, Ito K, Umemura E, Hara K, Nagasaka T, Abe A, Baba S, Furuichi Y, Izumi Y, Klein OD, Wakabayashi T.
- Journal Title
  
  Stem Cells
  
  Volume: 31 Issue: 3 Pages: 572-580
- DOI
  10.1002/stem.1300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461437
[Journal Article] Functionally Deregulated AML1/RUNX1 Cooperates with BCR-ABL to Induce a Blastic Phase-Like Phenotype of Chronic Myelogenous Leukemia in Mice.2013
- Author(s)
  Kiyoko Yamamoto, Shinobu Tsuzuki, Yosuke Minami, Yukiya Yamamoto, Akihiro Abe, Koichi Ohshima, Masao Seto, Tomoki Naoe.
- Journal Title
  
  PLOS ONE
  
  Volume: 8 Issue: 9 Pages: e74864-e74864
- DOI
  10.1371/journal.pone.0074864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591410, KAKENHI-PROJECT-24390249, KAKENHI-PROJECT-25461412, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25670449
[Journal Article] Donor single nucleotide polymorphism in the CCR9 gene affects the incidence of skin GVHD2010
- Author(s)
  Inamoto Y, Abe A, et al.
- Journal Title
  
  Bone Marrow Transplant 45
  
  Pages: 363-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] GATA-1 and GATA-2 binding to 3' enhancer of WT1 gene is essential for its transcription in acute leukemia and solid tumor cell lines. Leukemia2009
- Author(s)
  Furuhata A, Abe A, et al.
- Journal Title
  
  Leukemia 23
  
  Pages: 1270-1277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] N-acetylglucosaminyltransferase V regulates extravillous trophoblast invasion through glycosylation of alpha5betal integrin2009
- Author(s)
  Yamamoto E, Abe A, et al.
- Journal Title
  
  Endocrinology 150
  
  Pages: 990-999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] p27 deregulation by Skp2 overexpression induced by the JAK2V617 mutation2009
- Author(s)
  Furuhata A, Abe A, et al.
- Journal Title
  
  Biochem Biophys Res Commun. 383
  
  Pages: 411-416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] KW-2449, a novel multikinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation2009
- Author(s)
  Shiotsu Y, Abe A, et al.
- Journal Title
  
  Blood 114
  
  Pages: 1607-1617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] GATA-1 and GATA-2 binding to 3' enhancer of WT1 gene is essential for its transcription in acute leukemia and solid tumor cell lines2009
- Author(s)
  Furuhata A, Abe A, et al.
- Journal Title
  
  Leukemia. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] Spontaneous regression of aleukemic leukemia cutis harboring a NPM/RARA fusion gene in an infant with cutaneous mastosytosis2009
- Author(s)
  Kanegane H, Abe A, et al.
- Journal Title
  
  Int J Hematol. 89
  
  Pages: 86-90
- NAID
  10025159789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] Prognostic implication and biological roles of RhoH in acute myeloid leukaemia2008
- Author(s)
  Iwasaki T, Abe A, et al.
- Journal Title
  
  Eur J Haematol. 81
  
  Pages: 454-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] Retention But Significant Reduction of BCR-ABL Transcript in Hematopoietic Stem Cells in Chronic Myelogenous Leukemia After Imatinib Therapy2008
- Author(s)
  Abe A, Minami Y, et al.
- Journal Title
  
  Int J Hematol. 88
  
  Pages: 471-475
- NAID
  10023971017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] Clinical significance of nuclear non-phosphorylated beta-catenin in acute myeloid leukaemia and myelodysplastic syndrome2008
- Author(s)
  Xu J, Abe A, et al.
- Journal Title
  
  Br J Haematol. 140
  
  Pages: 394-401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] 【分子標的治療薬の基礎と臨床】細胞内情報伝達系を標的とする分子標的治療薬2008
- Author(s)
  安部明弘, 直江知樹
- Journal Title
  
  成人病と生活習慣病 38
  
  Pages: 637-641
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] Mutational analysis of SOS1 gene in acute myeloid leukemia2008
- Author(s)
  Tanizaki R, Abe A, et al.
- Journal Title
  
  Int J Hematol. 88
  
  Pages: 460-462
- NAID
  10023970986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] Acetylation of PML is involved in histone deacetylase inhibitor-mediated apoptosis2008
- Author(s)
  Hayakawa F, Abe A, et al.
- Journal Title
  
  J Biol Chem. 283
  
  Pages: 24420-24425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591120
[Journal Article] Expression cloning of oligomerization-activated genes with cell-proliferating.2004
- Author(s)
  Abe A, et al.
- Journal Title
  
  Biochem Biophys Res Commun 320(3)
  
  Pages: 920-926
- Data Source
  KAKENHI-PROJECT-16390276
[Presentation] TCF4-MAML3融合遺伝子を認めたCD4+CD56+芽球性NK細胞白血病の１例2019
- Author(s)
  安部明弘、山本幸也、山本秀行、徳田倍将、稲熊容子、岡本晃直、入山智沙子、冨田章裕、岡本昌隆、恵美宣彦
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09860
[Presentation] ETV6の再構成による異所性遺伝子発現を認めた急性骨髄性白血病の二症例2018
- Author(s)
  安部明弘、山本幸也、岡本晃直、入山智沙子、徳田倍将、稲熊容子、蟹江匡治、冨田章裕、赤塚美樹、岡本昌隆、亀山俊樹、前田　明、恵美宣彦
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09860
[Presentation] 再発急性骨髄性白血病において微小転座から複数のスプライシング産物を認めたRUNX1-GRIK2融合遺伝子2017
- Author(s)
  安部明弘、山本幸也、岡本晃直、徳田倍将、稲熊容子、柳田正光、蟹江匡治、冨田章裕、赤塚美樹、岡本昌隆、亀山俊樹、前田明、恵美宣彦
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09860
[Presentation] ETV6転座によるPDGFRαとGSX2の高発現を認めたt(4;12)を有するAMLの一例2016
- Author(s)
  安部明弘、水田秀一、山本幸也、岡本晃直、伊庭佐知子、徳田倍将、稲熊容子、柳田正光、森島聡子、蟹江匡治、富田章裕、赤塚美樹、岡本昌隆、亀山俊樹、前田明、恵美宣彦
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  神奈川県　横浜市　パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09860
[Presentation] t(8;12;21)(q22:p12;q22)を有するRUNX1-RUNX1T1白血病に認められたTM7SF4-VPS13B融合遺伝子2015
- Author(s)
  安部明弘、山本幸也、岡本晃直、徳田倍将、稲熊容子、山本起代子、柳田正光、森島聡子、蟹江匡治、赤塚美樹、水田秀一、岡本昌1、亀山俊樹２、前田　明、恵美宣彦
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢市
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25461437
[Presentation] Molecular response to nilotinib in a patient with imatinib-intolerant e19a2 chronic myeloid leukemia2013
- Author(s)
  梶口智弘、奥野真吾、大野稔人、安部明弘
- Organizer
  日本血液学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25461437
[Presentation] Evaluation of BCR-ABL-positive leukemia stem cells : strategies for over coming the resistance to imatinib2009
- Author(s)
  Minami Y, Abe A., et al.
- Organizer
  Gordon Research Conferences, Stem Cells & Cancer
- Place of Presentation
  Les Diablerets, Switzerland
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] Evaluation of BCR-ABL-positive leukemia stem cells with imatinib-therapy and apoptosis induced by bortezomib-treatment2009
- Author(s)
  南陽介、安部明弘, 他
- Organizer
  第7回幹細胞シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] Ph陽性白血病幹細胞におけるイマチニブ耐性とボルテゾミブによる克服の可能性2009
- Author(s)
  南陽介、安部明弘, 他
- Organizer
  第18回日本アポトーシス研究会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] Prognostic Implication and Biological Roles of RhoH in Acute Myeloid Leukemia2008
- Author(s)
  勝見章, 安部明弘, 他
- Organizer
  第50回米国血液学会
- Place of Presentation
  米国サンフランシスコ
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] MDS患者に認められたt(12 ; 17)により生じる新規TEL/ETV6融合遺伝子の解析2008
- Author(s)
  杉本匠, 安部明弘, 他
- Organizer
  第70回日本血液学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] Treatment with Hsp90 Inhibitor, 17-AAG Overcomes Resistance to Small Molecule FLT3-Inhibitors in FLT3/ITD-Positive Leukemia Cells Harboring N676K-Mutation2008
- Author(s)
  南陽介, 安部明弘, 他
- Organizer
  第50回米国血液学会
- Place of Presentation
  米国サンフランシスコ
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] KW-2449, a Novel Multi-Kinase Inhibitor, Suppresses the Growth of Imatinib-Resistant Ph+Leukemia Including BCR-ABL/T315I Both in Vitro and in Vivo2008
- Author(s)
  塩津行正, 南陽介, 安部明弘, 他
- Organizer
  第50回米国血液学会
- Place of Presentation
  米国サンフランシスコ
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] 慢性骨髄性白血病幹前駆細胞に対するイマチニブの効果マウス多能性造血細胞モデル及び治療後残存腫瘍解析2008
- Author(s)
  南陽介, 安部明弘, 他
- Organizer
  第70回日本血液学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] Philadelphia染色体陽性急性リンパ芽球性白血病由来Imatinib耐性株の樹立とその耐性化機序の解析2008
- Author(s)
  鈴木百子, 安部明弘, 他
- Organizer
  第70回日本血液学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] Transformation of E2A-Deficient Pluripotent Progenitors by BCR-ABL Generates Imatinib-Resistant Leukemic Stem Cells2008
- Author(s)
  南陽介, 安部明弘, 他
- Organizer
  第50回米国血液学会
- Place of Presentation
  米国サンフランシスコ
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] 慢性骨髄性白血病におけるイマチニブ治療後の白血病幹細胞残存の解析(Evaluation of residual leukemia stem cells in chronic myeloid leukemia with imatinib therapy)2008
- Author(s)
  南陽介, 安部明弘, 他
- Organizer
  第67回日本癌学会学術総会2008
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] 慢性骨髄性白血病に対するイマチニブ治療の検討 ELNに準じた臨床成績とBCR・ABL遺伝子残存2008
- Author(s)
  北村邦朗, 安部明弘, 他
- Organizer
  第70回日本血液学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] Gene Alterations and Expression of Hematopoietic Transcription Factors in Pediatric Acute Megakaryoblastic Leukemia (AMKL) : A Comparison of Down Syndrome (DS)-Associated AMKL with Non-DS-AMKL2008
- Author(s)
  濱麻人, 安部明弘, 他
- Organizer
  第50回米国血液学会
- Place of Presentation
  米国サンフランシスコ
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] FLT3/Auroraキナーゼ阻害剤KW-2449のT315I変異Bcr-Ablに対する有効性(KW-2449, a FLT3-and Aurora kinase-inhibitor, is promising against imatinib-resistant Bcr-Abl mutations including T315I)2008
- Author(s)
  谷崎亮平, 南陽介, 安部明弘, 他
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] Retention but Significant Reduction of BCR-ABL Transcript in Hemato poietic Stem Cells in Chronic Myelogenous Leukemia after Imatinib Therapy2008
- Author(s)
  安部明弘, 南陽介, 他
- Organizer
  第50回米国血液学会
- Place of Presentation
  米国サンフランシスコ
- Data Source
  KAKENHI-PROJECT-20591120
[Presentation] DEK-NUP214を有する急性骨髄性白血病に付加的に認められたNUP214-RAC1融合遺伝子
- Author(s)
  安部明弘、恵美宣彦ら
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25461437

1. NOBUHIKO Emi (30185144)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. NAOE Tomoki (50217634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KIYOI Hitoshi (90314004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 南陽介 (60513752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. 山本幸也 (90410703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. KATSUMI Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 亀山俊樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
8. 鈴木元

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 村手隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Abe Akihiro 安部 明弘

ABE Akihiro 安部 明弘

安部 明弘 アベ アキヒロ

Research Projects

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Co-Researchers

Identification and functional analysis of gene aberrations in hematological malignancy with complex chromosomal abnormality using RNA-seq analysisPrincipal Investigator

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Analyses of cytokine responsive signaling of LPXN and enhanced responses caused by ETV6-LPXNPrincipal Investigator

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慢性骨髄性白血病における分子標的治療後の残存腫瘍の高感度定量法と治療法の開発Principal Investigator

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Analysis of aberrant signal tansduction in hematological malignancy and development of treatment methods.

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[Journal Article] Truncated RUNX1 generated from the fusion of RUNX1 to antisense GRIK2 via a cryptic chromosome translocation enhances sensitivity to granulocyte colony-stimulating factor2020

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[Journal Article] Involvement of MCL1, c-myc, and cyclin D2 protein degradation in ponatinib-induced cytotoxicity against T315I(+) Ph+leukemia cells2020

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[Journal Article] BCL2 inhibitor ABT-199 and JNK inhibitor SP600125 exhibit synergistic cytotoxicity against imatinib-resistant Ph+ ALL cells.2018

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[Journal Article] Autologous hematopoietic cell transplantation for acute promyelocytic leukemia in second complete remission: outcomes before and after the introduction of arsenic trioxide2017

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[Journal Article] Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1-RUNX1T1 leukemia with t(8;12;21).2017

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[Journal Article] ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9.2016

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[Journal Article] Transcriptional activation of platelet-derived growth factor receptor α and GS homeobox 2 resulting from E26 transformation-specific variant 6 translocation in a case of acute myeloid leukemia with t(4;12)(q12;p13).2016

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[Journal Article] Wnt signaling is associated with cell survival in the interaction between acute myeloid leukemia cells and stromal cells2016

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[Journal Article] t(11;21)(p14;q22) RUNX1/KIAA1549L2015

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[Journal Article] NUP214-RAC1 and RAC1-COL12A1 Fusion in Complex Variant Translocations Involving Chromosomes 6, 7 and 9 in an Acute Myeloid Leukemia Case with DEK-NUP214.2015

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[Journal Article] A varicella outbreak in B-cell lymphoma patients receiving rituximab-containing chemotherapy.2014

Abe Akihiro 安部明弘

ABE Akihiro 安部明弘

安部明弘アベアキヒロ

[Journal Article] Truncated RUNX1 generated from the　fusion of RUNX1 to antisense GRIK2 via a cryptic chromosome translocation enhances　sensitivity　to granulocyte colony-stimulating factor2020