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Tokuda Shinsaku  徳田 深作

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… Alternative Names

徳田 深作  トクダ シンサク

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Researcher Number 00433277
Other IDs
Affiliation (Current) 2022: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Affiliation (based on the past Project Information) *help 2021: 京都府立医科大学, 医学(系)研究科(研究院), 助教
2016 – 2017: 京都大学, 医学研究科, 医員
2007: Kyoto Prefectural University of Medicine, 医学研究科, 助教
2006: 京都府立医科大学, 医学研究科, 助手
Review Section/Research Field
Principal Investigator
General physiology / Tumor biology / Basic Section 50010:Tumor biology-related
Except Principal Investigator
General physiology
Keywords
Principal Investigator
タイトジャンクション / クローディン / ENaC / カルモデュリン / 低浸透圧 / タイト結合 / 浸透圧 / アクチン / 静水圧 / 癌 … More / 細胞極性 / 細胞増殖 / プロテインキナーゼA / 肺癌 / 間質圧 / PKA … More
Except Principal Investigator
クロライドイオン / Akt / JNK / NKCC / VSOR / チロシンリン酸化 / 細胞死 Less
  • Research Projects

    (4 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (4 People)
  •  Elucidation of the role of the increase of interstitial pressure on the pathophysiology of lung cancer and the development of novel treatmentPrincipal Investigator

    • Principal Investigator
      徳田 深作
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Mechanism of the regulation of epithelial function by hydrostatic pressure and the application for canter treatmentPrincipal Investigator

    • Principal Investigator
      Tokuda Shinsaku
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
      General physiology
    • Research Institution
      Kyoto University
  •  Cell survival and apoptosis through Cl_-dependent regulation of Akt and JNK in renal epithelium

    • Principal Investigator
      NIISATO Naoml
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  低浸透圧によるカルモデュリン依存性ENaC局在の分子メカニズムの解明Principal Investigator

    • Principal Investigator
      徳田 深作
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      General physiology
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2017 2016 2008 2007

All Journal Article Presentation

  • [Journal Article] Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells2017

    • Author(s)
      Tokuda Shinsaku、Hirai Toyohiro、Furuse Mikio
    • Journal Title

      PLOS ONE

      Volume: 12

    • DOI

      10.1371/journal.pone.0182521

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K21101
  • [Journal Article] Effects of osmolality on paracellular transport in MDCK II cells2016

    • Author(s)
      Tokuda S, Hirai T, Furuse M
    • Journal Title

      PLoS One

      Volume: 11

    • NAID

      120005980913

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16K21101
  • [Journal Article] Regulation of the paracellular Na^+ and Cl^- conductances by the NaCl-generated osmotic gradient in a manner dependent on the direction of osmotic gradients.2008

    • Author(s)
      Tokuda, S.
    • Journal Title

      Biochemican and Biophysical Research Communications 366

      Pages: 464-470

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18890157
  • [Journal Article] Regulation of the paracellular Na^+ and Cl^- conductances by the NaCl-generated osmotic gradient in a manner dependent on the direction of osmotic gradients.2008

    • Author(s)
      Tokuda S, NIISATO N, Nakajima K, Marunaka Y.
    • Journal Title

      Biochem Biophys Res Commun 366

      Pages: 464-470

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590212
  • [Journal Article] Regulation of the paracellular Na+ and Cl- conductances by the NaCl-generated osmotic gradient in a manner dependent on the direction of osmotic gradients.2008

    • Author(s)
      Tokuda S, Niisato N, Nakajima K, Marunaka Y.
    • Journal Title

      Biochem Biophys Res Commun. 366(2)

      Pages: 464-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590212
  • [Journal Article] Action of neltenexine on anion secretion in human airway epithelia.2007

    • Author(s)
      Niisato N, Hasegawa I, Tokuda S, Taruno A, Nakajima K, Miyazaki H, Iwasaki Y, Marunaka Y.
    • Journal Title

      Biochem Biophys Res Commun 356(4)

      Pages: 1050-1055

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590212
  • [Journal Article] Regulation of paracellular ion conductances by NaCl gradients in renal epithelial cells.2007

    • Author(s)
      Tokuda S, Niisato N, Marunaka Y.
    • Journal Title

      Biochem Biophys Res Commun. 363(3)

      Pages: 566-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590212
  • [Journal Article] Regulation of paracellular ion conductances by NaCI gradients in renal epithelial cells2007

    • Author(s)
      Tokuda S, MISATO N, Marunaka Y.
    • Journal Title

      Biochem Biophys Res Commun 363

      Pages: 566-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590212
  • [Journal Article] Abnormal expression of ENaC and SGK1 mRNA induced by dietary sodium in Dahl salt-sensitively hypertensive rats.2007

    • Author(s)
      Aoi W, Niisato N, Sawabe Y, Miyazaki H, Tokuda S, Nishio K, Yoshikawa T, Marunaka Y.
    • Journal Title

      Cell Biol Int. 31(10)

      Pages: 1288-1291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590212
  • [Journal Article] Regulation of paracellular ion conductances by NaCl gradients in renal epithelial cells.2007

    • Author(s)
      Tokuda, S.
    • Journal Title

      Biochemican and Biophysical Research Communications 363

      Pages: 566-571

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18890157
  • [Journal Article] HCO_3^--dependent pH_i recovery and overacidification induced by NH_4^+ pulse in rat lung alveolar type II cells: HCO_3^--dependent NH_3 excretion from lungs?2007

    • Author(s)
      Tokuda S, Shimamoto C, Yoshida H, Murao H, Kishima G, Ito S, Kubota T, Hanafusa T, Sugimoto T, Niisato N, Marunaka Y, Nakahari T.
    • Journal Title

      Pflugers Arch. 455(2)

      Pages: 223-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590212
  • [Presentation] Effects of claudin-2 and claudin-4 knockouts in MDCK II cells2016

    • Author(s)
      Tokuda S, Hirai T, Furuse M
    • Organizer
      International conference "Tight junctions and their proteins"
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2016-08-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K21101
  • [Presentation] フラボノイドによる血圧制御の分子機構2007

    • Author(s)
      丸中良典、新里直美、青井渉、宮崎裕明、中島謙一、徳田深作
    • Organizer
      日本農芸化学会2007年度大会
    • Place of Presentation
      東京
    • Year and Date
      2007-03-24
    • Data Source
      KAKENHI-PROJECT-19590212
  • [Presentation] 浸透圧・静水圧による細胞間隙コンダクタンスの調節2007

    • Author(s)
      徳田 深作
    • Organizer
      第54回中部日本生理学会・第100回近畿生理学談話会 合同大会
    • Place of Presentation
      三重大学(津)
    • Year and Date
      2007-10-20
    • Data Source
      KAKENHI-PROJECT-18890157
  • 1.  NIISATO Naoml (00237645)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 2.  MARUNAKA Yoshinori (00127036)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 3.  MIYAZAKI Hiroaki (30360027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  NAKAJIMA Ken-ichi (40398392)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results

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