INOUE Jo 井上浄

… Alternative Names

INOUE Joe 井上浄

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Researcher Number	00433714
Affiliation (based on the past Project Information) *help	2016 – 2020: 慶應義塾大学, 政策・メディア研究科(藤沢), 特任准教授 2016: 慶應義塾大学, 先端生命科学研究所, 特任准教授 2015: 慶應義塾大学, その他の研究科, 准教授 2015: 慶應義塾大学, 政策・メディア研究科, 准教授 2012 – 2014: 京都大学, 医学(系)研究科(研究院), 助教 2011: 北里大学, 理学部, 講師 2007 – 2008: Kitasato University, 理学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy / Tumor immunology / Bacteriology (including Mycology) Except Principal Investigator Polymer/Textile materials / Polymer chemistry / Hematology / Bacteriology (including Mycology)
Keywords	Principal Investigator 自己免疫疾患 / liposome / Notch / 辺縁帯B細胞 / NKT細胞 / SPA-1 / がん / 胚中心 / 免疫老化 / COX-2 … More / dendritic cell / tumor / cox-2 / IFN-β / toll-like-receptor4 / vaccine / MyD88 / TRIF / CD14 / toll-like-recePtor 4 / lipopolysaccharide / 病原性 … More Except Principal Investigator 高分子合成 / 高分子機能材料 / 環状高分子 / 急性骨髄性白血病 / 慢性骨髄性白血病 / 人 / ヘルパーT細胞 / PD-1 / Eomesdermin / 年齢 / MDS / CLL / CML / 健常人 / T細胞 / 免疫老化 / PKDドメイン / アンカーリンク / 技術移転 / 再生医療 / 骨新生 / アンカーリング / 膠原線維 / 細胞外マトリックス / コラーゲン結合ドメイン / 細菌毒素 Less

The mechanism of autoimmune disease pathogenesis mediated by SPA-1 expressing cellsPrincipal Investigator
- Principal Investigator
  
  INOUE Joe
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Keio University
Applications of topological polymers to soft materials
- Principal Investigator
  
  Yamamoto Takuya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Polymer chemistry
- Research Institution
  Hokkaido University
Functional analysis of senescence-Associated T cells (SA-T)Principal Investigator
- Principal Investigator
  
  INOUE Joe
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University
  Kyoto University
Topology Effects of Polymers in Molecular Assemblies
- Principal Investigator
  
  Yamamoto Takuya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Polymer/Textile materials
- Research Institution
  Hokkaido University
  Tokyo Institute of Technology
Senescence associated T cells among healthy volunteer and patients with hematological cancer.
- Principal Investigator
  
  SUZUKI YUHKO
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fukushima Medical University
Preclinical study to elucidate molecular mechanism of matrix anchoring using bacterial proteins
- Principal Investigator
  
  MATSUSHITA Osamu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Okayama University
  Kitasato University
Regulation of anti-tumor immunity by targeting cyclooxygenase-2 expressing cellsPrincipal Investigator
- Principal Investigator
  
  INOUE Joe
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor immunology
- Research Institution
  Kyoto University
  Kitasato University
The recognition mechanism of liposomal LPSPrincipal Investigator
- Principal Investigator
  
  INOUE Joe
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kitasato University

All 2017 2016 2015 2014 2013 2012 2009 Other

All Journal Article Presentation

[Journal Article] Synthetic Biomarker Design Using Analyte-Responsive Acetaminophen2017
- Author(s)
  Nishihara, T. Inoue, J. Tabata, S. Murakami, S. Ishikawa, T. Saito, N. Fukuda, S. Tomita, M. Soga, T.
- Journal Title
  
  Chembiochem
  
  Volume: in press Issue: 10 Pages: 1-5
- DOI
  10.1002/cbic.201700023
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02485, KAKENHI-PROJECT-15J03449, KAKENHI-PROJECT-26460066, KAKENHI-PROJECT-16K21361
[Journal Article] 健常人での老化関連T細胞と、血液疾患の関わり2016
- Author(s)
  鈴木裕子、井上浄
- Journal Title
  
  BIO Clinica
  
  Volume: 31 Pages: 79-96
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461455
[Journal Article] Hydrogel Formation by the 'Topological Conversion' of Cyclic PLA-PEO Block Copolymers2016
- Author(s)
  Takuya Yamamoto, Kotaro Inoue, Yasuyuki Tezuka
- Journal Title
  
  Polym. J.
  
  Volume: 48 Issue: 4 Pages: 391-398
- DOI
  10.1038/pj.2015.134
- NAID
  120005906894
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01595, KAKENHI-PROJECT-26288099, KAKENHI-PROJECT-26310206, KAKENHI-PROJECT-15K13703
[Journal Article] A CD153+CD4+ T follicular cell population with cell-senescence features plays a crucial role in lupus pathogenesis via osteopontin production.2015
- Author(s)
  1.Tahir S, Fukushima Y, Sakamoto K, Sato K, Fujita H, Inoue J, Uede T, Hamazaki Y, Hattori M, Minato N.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 194 Issue: 12 Pages: 5725-5735
- DOI
  10.4049/jimmunol.1500319
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26450443, KAKENHI-PROJECT-26460066, KAKENHI-PROJECT-15K15151, KAKENHI-PUBLICLY-25111505, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24590580, KAKENHI-PUBLICLY-15H01154, KAKENHI-PLANNED-24111008
[Journal Article] Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia.2015
- Author(s)
  Doi K, Imai T, Kressler C, Yagita H, Agata Y, Vooijs M, Hamazaki Y, Inoue J, Minato N.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 7978-7985
- DOI
  10.1038/srep07978
- NAID
  120005555511
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390068, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-26460066, KAKENHI-PROJECT-26670136, KAKENHI-PROJECT-15K15151, KAKENHI-PUBLICLY-25111505, KAKENHI-PROJECT-24590580, KAKENHI-PLANNED-24111008
[Journal Article] Modification of Gene Expression, Proliferation, and Function of OP9 Stroma Cells by Bcr-Abl-Expressing Leukemia Cells2015
- Author(s)
  Supper E, Tahir S, Imai T, Inoue J, Minato N.
- Journal Title
  
  PLoS One
  
  Volume: 10(7) Issue: 7 Pages: e0134026-e0134026
- DOI
  10.1371/journal.pone.0134026
- NAID
  120005678188
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460066, KAKENHI-PLANNED-24111008
[Journal Article] Acceleration of periosteal bone formation by human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase.2014
- Author(s)
  Uchida K, Matsushita O, Naruse K, Mima T, Nishi N, Hattori S, Ogura T, Inoue G, Tanaka K, Takaso M.
- Journal Title
  
  J Biomed Mater Res A.
  
  Volume: 102 Issue: 6 Pages: 1737-1743
- DOI
  10.1002/jbm.a.34841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590516, KAKENHI-PROJECT-23790483, KAKENHI-PROJECT-24791560, KAKENHI-PROJECT-25670659, KAKENHI-PROJECT-26460527, KAKENHI-PROJECT-26861210
[Journal Article] Liposomal lipopolysaccharide initiates TRIF-dependent signaling pathway independent of CD142013
- Author(s)
  Watanabe S, Kumazawa Y, Inoue J
- Journal Title
  
  PLoS One.
  
  Volume: 8(4)
- NAID
  120005244422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701076
[Journal Article] Effects of CB-VEGF-A Injection in Rat Flap Models for Improved Survival.2013
- Author(s)
  Akimoto M, Takeda A, Matsushita O, Inoue J, Sakamoto K, Hattori M, Kounoike N, Uchinuma E.
- Journal Title
  
  Plast Reconstr Surg.
  
  Volume: 131 Issue: 4 Pages: 717-725
- DOI
  10.1097/prs.0b013e3182818b34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590516
[Journal Article] Intracellular delivery of lipopolysaccharide induces effective Th1-immune responses independent of IL-12.2013
- Author(s)
  Watanabe S, Inoue J
- Journal Title
  
  PLoS One
  
  Volume: 8
- NAID
  120005306995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701076
[Journal Article] Intracellular delivery of lipopolysaccharide induces effective Th1-immune responses independent of IL-122013
- Author(s)
  Watanabe S#, Inoue J#*
- Journal Title
  
  PLoS One.
  
  Volume: 8(7)
- NAID
  120005306995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701076
[Journal Article] Liposomal lipopolysaccharide initiates TRIF-dependent signaling pathway independent of CD14.2013
- Author(s)
  Watanabe S, Kumazawa Y, Inoue J
- Journal Title
  
  PLoS One
  
  Volume: 8
- NAID
  120005244422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701076
[Journal Article] Acceleration of bone formation during fracture healing by injectable collagen powder and human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase2013
- Author(s)
  Saito W, Uchida K, Ueno M, MatsushitaO, Inoue G, Nishi N, Ogura T, Hattori S, Fujimaki H, Tanaka K, Takaso M
- Journal Title
  
  J Biomed Mater Res A
  
  Volume: in press Issue: 9 Pages: 3049-3055
- DOI
  10.1002/jbm.a.34974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590516, KAKENHI-PROJECT-24791560, KAKENHI-PROJECT-25670659, KAKENHI-PROJECT-26460527, KAKENHI-PROJECT-26861210
[Journal Article] Liposomal lipopolysaccharide initiates TRIF-dependent signaling pathway independent of CD14.2013
- Author(s)
  Sachiko Watanabe, Yoshio Kumazawa Y, Joe Inoue
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 4 Pages: e60078-e60078
- DOI
  10.1371/journal.pone.0060078
- NAID
  120005244422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701076
[Journal Article] Liposomal glycosphingolipids activate natural killer T cell-mediated immune responses through the endosomal pathway.2009
- Author(s)
  井上浄、井手上隆一、高橋大輔、久保田政宏、熊沢義雄
- Journal Title
  
  Journal of Controlled Release 133
  
  Pages: 18-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790326
[Presentation] Human Immunosenescence2015
- Author(s)
  SUZUKI Yuhko, INOUE Joe, OHTO Hitoshi, MINATO Nagahiro
- Organizer
  免疫細胞療法研究会
- Place of Presentation
  福島県立医大
- Year and Date
  2015-04-20
- Invited
- Data Source
  KAKENHI-PROJECT-25461455
[Presentation] Human immuno-senecescence2015
- Author(s)
  鈴木裕子、井上浄、大戸斉、湊長博
- Organizer
  免疫細胞療法研究会
- Place of Presentation
  福島
- Year and Date
  2015-04-20
- Invited
- Data Source
  KAKENHI-PROJECT-25461455
[Presentation] Human senescence associated T cells with high expression of Eomesdermin are increasing in B-cell malignancies2015
- Author(s)
  SUZUKI Yuhko, INOUE Joe, MINATO Nagahiro
- Organizer
  The 44th annual meeting of the Japanese Society for Immunology
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461455
[Presentation] 両親媒性環状および直鎖状ブロック共重合体に包摂したゲスト分子の放出挙動2015
- Author(s)
  松峰陸、手塚育志、井上浄、山本拓矢
- Organizer
  第64回高分子学会年次大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-05-27
- Data Source
  KAKENHI-PROJECT-15K13703
[Presentation] Rap1/SPA-1によるNKT細胞の分化制御2015
- Author(s)
  井上浄、濱崎洋子、湊長博
- Organizer
  Kyoto T cell Conference
- Place of Presentation
  京都：京都大学　芝蘭会館
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-26460066
[Presentation] Human senescence associated T cells exhibit high expression of Eomesdermin2014
- Author(s)
  SUZUKI Yuhko, INOUE Joe, MINATO Nagahiro.
- Organizer
  The 43rd annual meeting of the Japanese Society for Immunology
- Place of Presentation
  Kyoto
- Year and Date
  2014-12-10
- Data Source
  KAKENHI-PROJECT-25461455
[Presentation] PD-1+ memory phenotypes CD4+Th-1like cells underlie T cell immunodepression in senescence2013
- Author(s)
  Yuhko Susuzki, Joe Inoue, Nagahiro Minato
- Organizer
  Annual meeting of the Japanese Soceiety for immunology, 2013
- Place of Presentation
  Makuhari Messe, Chiba, Japan
- Data Source
  KAKENHI-PROJECT-25461455
[Presentation] Bacterial collagen-binding domains - Molecular basics and clinical applications2012
- Author(s)
  Osamu Matsushita, Takehiko Mima, Eijiro Adachi, Joshua Sakon, Nozomu Nishi, Takenori Miyashita, NozomuMori, JoeInoue, Masakazu Hattori, Minekatsu Akimoto, Akira Takeda, Eiju Uchinuma
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎県長崎市
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-23590516
[Presentation] LPSの細胞内認識とシグナル伝達機構に関する検討2009
- Author(s)
  渡辺幸子、井上浄
- Organizer
  特定領域研究「感染現象のマトリックス」第7回感染症沖縄フォーラム
- Place of Presentation
  沖縄県那覇市沖縄県青年会館
- Data Source
  KAKENHI-PROJECT-19790326
[Presentation] LPSの細胞内認識とシグナル伝達機構に関する検討、特定領域研究「感染現象のマトリックス」2009
- Author(s)
  井上浄、渡辺幸子
- Organizer
  第7回感染症沖縄フォーラム
- Place of Presentation
  沖縄県那覇市
- Data Source
  KAKENHI-PROJECT-19790326
[Presentation] 光開裂性環状ポリ乳酸を利用したステレオコンプレックスの形成制御
- Author(s)
  山本拓矢、菅井直人、井上航太郎、浅井茂雄、手塚育志
- Organizer
  平成26年度繊維学会年次大会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-26288099
[Presentation] 光開裂性環状PLA-PEOブロック共重合体の合成および環－鎖トポロジー変換に基づくゲル形成の制御
- Author(s)
  井上航太郎、菅井直人、山本拓矢、手塚育志
- Organizer
  第63回高分子学会年次大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2014-05-28 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-26288099
[Presentation] 光開裂性環状ポリ乳酸ブロック共重合体を利用したステレオコンプレックス形成によるゲル化制御
- Author(s)
  山本拓矢、井上航太郎、菅井直人、手塚育志
- Organizer
  第63回高分子討論会
- Place of Presentation
  長崎大学
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-26288099
[Presentation] 光開裂部位を持つ環状ポリ乳酸のステレオコンプレックス形成と応用
- Author(s)
  山本拓矢、菅井直人、井上航太郎、浅井茂雄、手塚育志
- Organizer
  第60回高分子研究発表会（神戸）
- Place of Presentation
  兵庫県民会館
- Year and Date
  2014-07-24 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-26288099
[Presentation] Senescence associated follicular CD4+T cell population underlies systemic lupus erythematosus
- Author(s)
  Suhail TAHIR, Yuji FUKUSHIMA, Keiko SAKAMOTO, Kyosuke SATO, Joe INOUE, Masakazu HATTORI, Yoko HAMAZAKI, Nagahiro MINATO
- Organizer
  第43回　日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26460066

1. Yamamoto Takuya (30525986)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. 手塚育志 (80155457)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. MATSUSHITA Osamu (00209537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. ADACHI Eijiro (30110430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. MORI Nozomu (90124883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. UCHIDA Kentaro (50547578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. MIMA Takehiko (80596437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. MIYASHITA Takenori (60363214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. SUZUKI YUHKO (80406941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. MINATO Nagahiro (40137716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 福島祐二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 服部雅一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 斎藤菜摘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 縣保年

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

INOUE Jo 井上 浄

INOUE Joe 井上 浄

Research Projects

Research Products

Co-Researchers

The mechanism of autoimmune disease pathogenesis mediated by SPA-1 expressing cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Applications of topological polymers to soft materials

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of senescence-Associated T cells (SA-T)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Topology Effects of Polymers in Molecular Assemblies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Senescence associated T cells among healthy volunteer and patients with hematological cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Preclinical study to elucidate molecular mechanism of matrix anchoring using bacterial proteins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of anti-tumor immunity by targeting cyclooxygenase-2 expressing cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The recognition mechanism of liposomal LPSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Synthetic Biomarker Design Using Analyte-Responsive Acetaminophen2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 健常人での老化関連T細胞と、血液疾患の関わり2016

Author(s)

Journal Title

Data Source

[Journal Article] Hydrogel Formation by the 'Topological Conversion' of Cyclic PLA-PEO Block Copolymers2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] A CD153+CD4+ T follicular cell population with cell-senescence features plays a crucial role in lupus pathogenesis via osteopontin production.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Modification of Gene Expression, Proliferation, and Function of OP9 Stroma Cells by Bcr-Abl-Expressing Leukemia Cells2015

INOUE Jo 井上浄

INOUE Joe 井上浄