Sadaoka Tomohiko 定岡知彦

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SADAOKA Tomohiko 定岡知彦

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Researcher Number	00435893
Other IDs	https://orcid.org/0000-0001-7951-6904
Affiliation (Current)	2026: 藤田医科大学, 感染症研究センター, 准教授
Affiliation (based on the past Project Information) *help	2026: 藤田医科大学, 感染症研究センター, 准教授 2024: 藤田医科大学, その他部局等, 准教授 2021 – 2023: 神戸大学, 医学研究科, 助教 2017 – 2019: 神戸大学, 医学研究科, 助教 2012: 神戸大学, 医学(系)研究科(研究院), 助教 … More 2011: 神戸大学, 大学院・医学研究科, 助教 2009 – 2011: Kobe University, 医学研究科, 助教 2009: National Institute of Biomedical Innovation, 大学院・医学研究科, 助教 2008: National Institute of Biomedical Innovation, 基盤研究部, 研究員 Less
Review Section/Research Field	Principal Investigator Virology / Basic Section 49060:Virology-related / Biological Sciences
Keywords	Principal Investigator 水痘帯状疱疹ウイルス / 潜伏感染 / ウイルス / 感染症 / エピジェネティクス / 融合転写産物 / 再活性化 / ヒト遺伝子融合ウイルス遺伝子産物 / 神経細胞 / 共生 … More / ヒトとウイルスの共生 / 弱毒化分子機構 / 弱毒化メカニズム / ウイルス糖タンパク / 生ワクチン / 弱毒化機構 / 弱毒生ワクチン / 新規遺伝子産物 / 分子 / 分子間相互作用 / テグメントタンパク / ウイルス粒子 / ウイルス粒子形成 / ウイルス粒子出芽 / 抗ウイルス薬 / ウイルス粒子成熟 / 出芽・抗ウイルス薬 / 感染症・ウイルス粒子成熟 Less

水痘帯状疱疹ウイルス感染性ウイルス粒子放出機構の解明Principal Investigator
- Principal Investigator
  
  定岡知彦
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Fujita Health University
Investigation of varicella-zoster virus latency and reactivation mechanismPrincipal Investigator
- Principal Investigator
  
  Sadaoka Tomohiko
- Project Period (FY)
  2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Fujita Health University
  Kobe University
Molecular machanism of varicella-zoster vaccine virus attenuationPrincipal Investigator
- Principal Investigator
  
  Sadaoka Tomohiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kobe University
宿主・ウイルス間ヘテロトランススプライシング遺伝子発現制御による共生機構の解明Principal Investigator
- Principal Investigator
  
  定岡知彦
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
水痘帯状疱疹ウイルス新規遺伝子産物を標的とした潜伏感染機構の解明Principal Investigator
- Principal Investigator
  
  定岡知彦
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kobe University
Functional analysis of varicella-zoster virus ORF49 and ORF44Principal Investigator
- Principal Investigator
  
  SADAOKA Tomohiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Kobe University
Functional analysis of Varicella-zoster virus encoding ORF49Principal Investigator
- Principal Investigator
  
  SADAOKA Tomohiko
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Biomedical Innovation

All 2025 2024 2023 2022 2021 2020 2019 2018 2017 2012 2011 2010 2009 2008

All Journal Article Presentation Book

[Book] Varicella-zoster vrus glycoprotein M(Current topics in microbiology and immunology, vol.342)2010
- Author(s)
  Mori Yasuko, Tomohiko Sadaoka
- Total Pages
  342
- Publisher
  Springer(published online ahead of the print)
- Data Source
  KAKENHI-PROJECT-20790363
[Journal Article] Author Correction: Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication2023
- Author(s)
  Tanaka Junichi、Senpuku Hidenobu、Ogawa Miho、Yasuhara Rika、Ohnuma Shintaro、Takamatsu Koki、Watanabe Takashi、Mabuchi Yo、Nakamura Shiro、Ishida Shoko、Sadaoka Tomohiko、Takaki Takashi、Shirota Tatsuo、Shimane Toshikazu、Inoue Tomio、Sakai Takayoshi、Mori Munemasa、Tsuji Takashi、Saito Ichiro、Mishima Kenji
- Journal Title
  
  Nature Cell Biology
  
  Volume: 25 Issue: 3 Pages: 508-508
- DOI
  10.1038/s41556-023-01107-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K21379
[Journal Article] Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication.2022
- Author(s)
  Junichi Tanaka, Hidenobu Senpuku, Miho Ogawa, Rika Yasuhara, Shintaro Ohnuma, Koki Takamatsu, Takashi Watanabe, Yo Mabuchi, Shiro Nakamura, Shoko Ishida, Tomohiko Sadaoka, Takashi Takaki, Tatsuo Shirota, Toshikazu Shimane, Tomio Inoue, Takayoshi Sakai, Munemasa Mori, Takashi Tsuji, Ichiro Saito, Kenji Mishima
- Journal Title
  
  Nat Cell Biol.
  
  Volume: 24(11) Issue: 11 Pages: 1595-1605
- DOI
  10.1038/s41556-022-01007-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09845, KAKENHI-PROJECT-19KK0230, KAKENHI-PROJECT-19H03852, KAKENHI-PROJECT-19K07423, KAKENHI-PROJECT-19K10024, KAKENHI-PROJECT-19K10048, KAKENHI-PROJECT-20K21688, KAKENHI-PROJECT-18KK0449, KAKENHI-PROJECT-23K21379
[Journal Article] A Variant Allele in Varicella-Zoster Virus Glycoprotein B Selected during Production of the Varicella Vaccine Contributes to Its Attenuation2022
- Author(s)
  Sadaoka Tomohiko、Depledge Daniel P.、Rajbhandari Labchan、Breuer Judith、Venkatesan Arun、Cohen Jeffrey I.
- Journal Title
  
  mBio
  
  Volume: 13 Issue: 4
- DOI
  10.1128/mbio.01864-22
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21379
[Journal Article] Mutagenesis of the Varicella-Zoster Virus Genome Demonstrates That VLT and VLT-ORF63 Proteins Are Dispensable for Lytic Infection2021
- Author(s)
  Braspenning Shirley E.、Lebbink Robert Jan、Depledge Daniel P.、Schapendonk Claudia M. E.、Anderson Laura A.、Verjans Georges M. G. M.、Sadaoka Tomohiko、Ouwendijk Werner J. D.
- Journal Title
  
  Viruses
  
  Volume: 13 Issue: 11 Pages: 2289-2289
- DOI
  10.3390/v13112289
- NAID
  120007177521
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21379
[Journal Article] Nectin-1 Is an Entry Mediator for Varicella-Zoster Virus Infection of Human Neurons2021
- Author(s)
  Rajbhandari Labchan、Shukla Priya、Jagdish Balaji、Mandalla Abby、Li Qingxue、Ali Mir A.、Lee Hojae、Lee Gabsang、Sadaoka Tomohiko、Cohen Jeffrey I.、Venkatesan Arun
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 22
- DOI
  10.1128/jvi.01227-21
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21379
[Journal Article] Epstein-Barr virus tegument protein BGLF2 suppresses type I IFN signaling to promote EBV reactivation2020
- Author(s)
  Liu XueQiao、Sadaoka Tomohiko、Krogmann Tammy、Cohen Jeffrey I.
- Journal Title
  
  Journal of Virology
  
  Volume: in press Issue: 11
- DOI
  10.1128/jvi.00258-20
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08858
[Journal Article] Human stem cell derived sensory neurons are positioned to support varicella zoster virus latency2020
- Author(s)
  Sadaoka Tomohiko、Rajbhandari Labchan、Shukla Priya、Jagdish Balaji、Lee Hojae、Lee Gabsang、Venkatesan Arun
- Journal Title
  
  bioRxiv
  
  Volume: なし Pages: 1-22
- DOI
  10.1101/2020.01.24.919290
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08858
[Journal Article] 先端技術による水痘帯状疱疹ウイルス潜伏感染機構の解明を目指して2019
- Author(s)
  定岡知彦
- Journal Title
  
  臨床とウイルス
  
  Volume: 4 Pages: 261-268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08858
[Journal Article] Direct RNA sequencing on nanopore arrays redefines the transcriptional complexity of a viral pathogen2019
- Author(s)
  Depledge Daniel P.、Srinivas Kalanghad Puthankalam、Sadaoka Tomohiko、Bready Devin、Mori Yasuko、Placantonakis Dimitris G.、Mohr Ian、Wilson Angus C.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 754-754
- DOI
  10.1038/s41467-019-08734-9
- NAID
  120006559317
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08858, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05816
[Journal Article] A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 612018
- Author(s)
  Depledge Daniel P.、Ouwendijk Werner J. D.、Sadaoka Tomohiko、Braspenning Shirley E.、Mori Yasuko、Cohrs Randall J.、Verjans Georges M. G. M.、Breuer Judith
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 1167-1167
- DOI
  10.1038/s41467-018-03569-2
- NAID
  120006454532
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08858, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05816
[Journal Article] Vaccine Development for Varicella-Zoster Virus2018
- Author(s)
  Sadaoka Tomohiko、Mori Yasuko
- Journal Title
  
  Advances in Experimental Medicine and Biology
  
  Volume: 1045 Pages: 123-142
- DOI
  10.1007/978-981-10-7230-7_7
- ISBN
  9789811072291, 9789811072307
- Data Source
  KAKENHI-PROJECT-17K08858, KAKENHI-PUBLICLY-17H05816
[Journal Article] Molecular Aspects of Varicella-Zoster Virus Latency2018
- Author(s)
  Depledge Daniel、Sadaoka Tomohiko、Ouwendijk Werner
- Journal Title
  
  Viruses
  
  Volume: 10 Issue: 7 Pages: 349-349
- DOI
  10.3390/v10070349
- NAID
  120006529674
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08858, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05816
[Journal Article] Human embryonic stem cell derived neurons are highly permissive for varicella-zoster virus lytic infection2018
- Author(s)
  Tomohiko Sadaoka, Cindi Schwartz, Labchan Rajbhandari, Arun Venkatesan, Jeffrey I. Cohen
- Journal Title
  
  Journal of Virology
  
  Volume: 92 Issue: 1
- DOI
  10.1128/jvi.01108-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08858, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05816
[Journal Article] Role of JNK pathway in varicella-zoster virus lytic infection and reactivation2017
- Author(s)
  Sravya Kurapati, Tomohiko Sadaoka, Labchan Rajbhandari, Balaji Jagdish, Priya Shukla, Yong Jun Kim, Gabsang Lee, Jeffrey I. Cohen, Arun Venkatesan
- Journal Title
  
  Journal of Virology
  
  Volume: 91 Issue: 17
- DOI
  10.1128/jvi.00640-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08858, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05816
[Journal Article] Characterization of the Varicella-Zoster Virus ORF50 Gene, which Encodes Glycoprotein M2010
- Author(s)
  Tomohiko Sadaoka, Tatsuya Yanagi, Koichi Yamanishi, Yasuko Mori
- Journal Title
  
  Journal of Virology Vol.84No.7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790363
[Journal Article] Varicella-Zoster Virus glycoprotein M2010
- Author(s)
  Yasuko Mori, Tomohiko Sadaoka
- Journal Title
  
  Current Topics in Microbiology and Immunology
  
  Volume: 342 Pages: 147-157
- Data Source
  KAKENHI-PROJECT-22790432
[Journal Article] Characterization of the Varicella-Zoster Virus ORF50 Gene, which Encodes Glycoprotein M2010
- Author(s)
  Tomohiko Sadaoka, Tatsuya Yanagi, Koichi Yamanishi, Yasuko Mori
- Journal Title
  
  Journal of Virology Published online ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790363
[Journal Article] Characterization of the Varicella-Zoster Virus ORF50 Gene, which Encodes Glycoprotein M2010
- Author(s)
  Tomohiko Sadaoka, Tatsuya Yanagi, Koichi Yamanishi, Yasuko Mori
- Journal Title
  
  Journal of Virology
  
  Volume: Vol.84 No.7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790432
[Journal Article] Varicella-Zoster Virus glycoprotein M2010
- Author(s)
  Yasuko Mori, Tomohiko Sadaoka
- Journal Title
  
  Current Topics in Microbiology andImmunology
  
  Volume: 342 Pages: 147-154
- Data Source
  KAKENHI-PROJECT-22790432
[Journal Article] Human herpesvirus-6 and humanherpesvirus-72010
- Author(s)
  Huamin Tang, Tomohiko Sadaoka, Yasuko Mori
- Journal Title
  
  VIRUS
  
  Volume: Vol.60 No.2 Pages: 221-236
- Data Source
  KAKENHI-PROJECT-22790432
[Journal Article] Varicella-zoster virus ORF1 gene product is a tail-anchored membrane protein localized to plasma membrane and trans-Golgi network in infected cells2008
- Author(s)
  Tetsuo Koshizuka, Tomohiko Sadaoka, Hironori Yoshii, Koichi Yamanishi, Yasuko Mori
- Journal Title
  
  Virology Vol.377
  
  Pages: 279-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790363
[Journal Article] Varicella-zoster virus ORF1 gene product is a tail-anchored membrane protein localized to plasma membrane and trans-Golgi network in infected cells2008
- Author(s)
  Tetsuo Koshizuka, Tomohiko Sadaoka, Hironori Yoshii, Koichi Yamanishi, Yasviko Mori
- Journal Title
  
  Virology 377
  
  Pages: 289-295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790363
[Presentation] U1 snRNP regulates transcription across the Varicella Zoster Virus latency locus2025
- Author(s)
  Carolin Vogt, Jonathan S Abebe, Maximilian Huwald, Lars Steinbruck, Werner JD Ouwendijk, Abel Viejo-Borbolla, Tomohiko Sadaoka, Jens Bohne, Daniel P Depledge
- Organizer
  49th Annual International Herpesvirus Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21379
[Presentation] Cloning of a VZV clinical isolate EMC-1 as an infectious BAC clone and investigation of genes responsible for its multinucleated giant cell formation2025
- Author(s)
  Tomohiko Sadaoka, Alexander C. Havelaar, Niclas Ritter, Lars Steinbruck, Saori Fukuda, Tomoki Inagaki, Georges M. G. M. Verjans, Takayuki Murata, Daniel P. Depledge, Werner J. D. Ouwendijk
- Organizer
  49th Annual International Herpesvirus Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21379
[Presentation] A human sensory neuron model for Varicella-Zoster Virus latency and reactivation in vitro2025
- Author(s)
  Alexander C. Havelaar, Joseph Flot, Tomohiko Sadaoka, Anna Cliffe, Abigail Whitford, Amber J. Schotting, Sem van't Geloof, Paul R. Kinchington, Georges M.G.M. Verjans, Werner J.D. Ouwendijk
- Organizer
  49th Annual International Herpesvirus Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21379
[Presentation] HD10.6 cells: a novel human sensory neuron model for VZV latency2024
- Author(s)
  Alexander C. Havelaar, Anna Cliffe, Tomohiko Sadaoka, Amber J. Schotting, Paul R. Kinchington, Georges M.G.M. Verjans, Werner J.D. Ouwendijk
- Organizer
  48th Annual International Herpesvirus Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21379
[Presentation] U1 snRNP-mediated regulation of the Varicella Zoster Virus latent to lytic switch2024
- Author(s)
  Carolin Vogt, Jonathan S Abebe, Jiayi Wang, Lars Steinbruck, Werner JD Ouwendijk, Abel Viejo-Borbolla, Tomohiko Sadaoka, Jens Bohne, Daniel P Depledge
- Organizer
  48th Annual International Herpesvirus Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21379
[Presentation] Absence of antibodies to the protein encoded by the VZV latency associated transcript in persons with zoster2023
- Author(s)
  Mir A. Ali, Tomohiko Sadaoka, Judith Breuer, Mark Quinlivan, Jeffrey I. Cohen
- Organizer
  International Herpesvirus Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21379
[Presentation] Identification of a novel responsible factor for attenuation of vOka, a live attenuated varicella-zoster virus vaccine2022
- Author(s)
  Tomohiko Sadaoka, Daniel P. Depledge, Labchan Rajbhandari, Judith Breuer, Arun Venkatesan, Jeffrey I. Cohen
- Organizer
  第69回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-23K21379
[Presentation] Human iPS cell-derived sensory neurons to study VZV latency and reactivation2021
- Author(s)
  Tomohiko Sadaoka
- Organizer
  1st International Varicella-Zoster Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21379
[Presentation] Co-existence of two latency transcripts? -New insight into the transition from latency to lytic VZV infection-2021
- Author(s)
  Tomohiko Sadaoka
- Organizer
  45th Annual International Herpesvirus Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21379
[Presentation] Novel Fusion Transcript of VZV VLT and ORF63 Facilitates Broad Viral Transcription in Latently Infected iPSC-derived Human Sensory Neurons2019
- Author(s)
  Tomohiko Sadaoka, Werner J. D. Ouwendijk, Daniel P. Depledge, Labchan Rajbhandari, Judith Breuer, Georges M. G. M. Verjans, Arun Venkatesan, Yasuko Mori
- Organizer
  44th Annual International Herpesvirus Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08858
[Presentation] 水痘帯状疱疹ウイルス潜伏感染関連遺伝子発見とin vitro再現系の構築2019
- Author(s)
  定岡知彦、森康子
- Organizer
  第122回日本小児科学会学術集会
- Data Source
  KAKENHI-PUBLICLY-17H05816
[Presentation] A novel fusion of the VZV latency-associated transcript and ORF63 facilitates reactivation2019
- Author(s)
  Tomohiko Sadaoka, Werner J. D. Ouwendijk, Daniel P. Depledge, Labchan Rajbhandari, Judith Breuer, Georges M. G. M. Verjans, Arun Venkatesan, Yasuko Mori
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08858
[Presentation] 水痘帯状疱疹ウイルス潜伏感染関連遺伝子発見とin vitro再現系の構築2019
- Author(s)
  定岡知彦、森康子
- Organizer
  第122回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08858
[Presentation] 先端技術による水痘帯状疱疹ウイルス潜伏感染機構の解明を目指して2019
- Author(s)
  定岡知彦
- Organizer
  第60回日本臨床ウイルス学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08858
[Presentation] 先端技術による水痘帯状疱疹ウイルス潜伏感染機構の解明を目指して2019
- Author(s)
  定岡知彦
- Organizer
  第66回日本臨床ウイルス学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05816
[Presentation] Transcriptional complexity of the varicella-zoster virus latency-associated transcript2018
- Author(s)
  Tomohiko Sadaoka, Werner J.D. Ouwendijk, Daniel P. Depledge, Judith Breuer, Georges M. G. M. Verjans, Yasuko Mori
- Organizer
  43rd Annual International Herpesvirus Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08858
[Presentation] Transcriptional complexity of the varicella-zoster virus latency-associated transcript2018
- Author(s)
  Tomohiko Sadaoka, Werner J.D. Ouwendijk, Daniel P. Depledge, Judith Breuer, Georges M. G. M. Verjans, Yasuko Mori
- Organizer
  43rd International Herpesvirus Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05816
[Presentation] Identification of a novel varicella-zoster virus latency transcript that represses expression of the viral ORF61 regulatory gene2017
- Author(s)
  Daniel P. Depledge†, Werner J. D. Ouwendijk†, Tomohiko Sadaoka†, Shirley E. Braspenning, Yasuko Mori, Randall J. Cohrs, Georges M. G. M. Verjans, Judith Breuer (†; Joint First Author)
- Organizer
  The 42nd Annual International Herpesvirus Workshop
- Data Source
  KAKENHI-PUBLICLY-17H05816
[Presentation] An allele selection within ORF31 gene which encodes glycoprotein B, which occurred during production of the varicella-zoster virus vaccine, contributes to its attenuation2017
- Author(s)
  Tomohiko Sadaoka, Daniel P. Depledge, Labchan Rajbhandari, Arun Venkatesan, Jeffrey I. Cohen, Judith Breuer, Yasuko Mori
- Organizer
  The 42nd Annual International Herpesvirus Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08858
[Presentation] Novel varicella-zoster virus latency transcript inhibits viral replication2017
- Author(s)
  Tomohiko Sadaoka†, Daniel P. Depledge†, Werner J. D. Ouwendijk†, Shirley E. Braspenning, Yasuko Mori, Randall J. Cohrs, Georges M. G. M. Verjans, Judith Breuer (†; Joint First Author)
- Organizer
  The 65th Annual Meeting of the Japanese Society for Virology
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05816
[Presentation] 水痘帯状疱疹ウイルスにおける新規遺伝子産物の発見とその機能解析2012
- Author(s)
  定岡知彦
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪市グランキューブ大阪
- Data Source
  KAKENHI-PROJECT-24590551
[Presentation] 水痘帯状疱疹ウイルスORF44とORF49の相互作用に関する解析2011
- Author(s)
  定岡知彦、林麻佑子、山西弘一、森康子
- Organizer
  第26回ヘルペスウイルス研究会
- Place of Presentation
  大阪府大阪市
- Data Source
  KAKENHI-PROJECT-22790432
[Presentation] Interaction Mechanism of Varicell-Zoster Virus Tegument Proteins, ORF44 and ORF49 Conserved Among Herpesviruses2011
- Author(s)
  Tomohiko Sadaoka, Mayuko Hayashi, Koichi Yamanishi, Yasuko Mori
- Organizer
  36th Annual International Herpesvirus Workshop IHW
- Place of Presentation
  Gdansk, Poland
- Data Source
  KAKENHI-PROJECT-22790432
[Presentation] Interaction Mechanism of Varicella-Zoster Virus Tegument Proteins, ORF44 and ORF49 Conserved Among Herpesviruses2011
- Author(s)
  Tomohiko Sadaoka, Mayuko Hayashi, Koichi Yamanishi, Yasuko Mori
- Organizer
  36^<th> Annual International Herpesvirus Workshop
- Place of Presentation
  Gdansk, Poland
- Data Source
  KAKENHI-PROJECT-22790432
[Presentation] 水痘帯状疱疹ウイルスORF44の解析2010
- Author(s)
  定岡知彦、林麻佑子、山西弘一、森康子
- Organizer
  第25回ヘルペスウイルス研究会
- Place of Presentation
  静岡県浜松市
- Data Source
  KAKENHI-PROJECT-22790432
[Presentation] 水痘帯状疱疹ウイルスORF44とORF49における詳細な相互作用解析2010
- Author(s)
  定岡知彦、林麻佑子、山西弘一、森康子
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島県郷土文化会館(徳島県)
- Data Source
  KAKENHI-PROJECT-22790432
[Presentation] 水痘帯状疱疹ウイルスORF44の解析2010
- Author(s)
  定岡知彦、林麻佑子、山西弘一、森康子
- Organizer
  第25回ヘルペスウイルス研究会
- Place of Presentation
  カリアック商工会議所福利研修センター(静岡県)
- Data Source
  KAKENHI-PROJECT-22790432
[Presentation] 水痘帯状疱疹ウイルスORF44とORF49における詳細な相互作用解析2010
- Author(s)
  定岡知彦、林麻佑子、山西弘一、森康子
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島県徳島市
- Data Source
  KAKENHI-PROJECT-22790432
[Presentation] Newly identified mRNA arisen from VZV ORF50 gene region was not essential for viral growth2009
- Author(s)
  Tetsuo Koshizuka, Tomohiko Sadaoka, Hironori Yoshii, Koichi Yamanishi, Yasuko Mori
- Organizer
  34th International Herpesvirus Workshop IHW
- Place of Presentation
  Ithaca, New York, USA
- Data Source
  KAKENHI-PROJECT-20790363
[Presentation] 水痘帯状萢疹ウイルスglycoprotein Mの成熟機構の解析2009
- Author(s)
  定岡知彦、山西弘一、森康子
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  都市センターホテル(東京都)
- Data Source
  KAKENHI-PROJECT-20790363
[Presentation] VZV glycoprotein M and glycoprotein N assist each other for their functions.2009
- Author(s)
  Tomohiko Sadaoka, Koichi Yamanishi, Yasuko Mori
- Organizer
  14^<th> International Conference on Immunobiology and Prophylaxis of Human Herpesvirus Infections
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-20790363
[Presentation] 水痘帯状疱疹ウイルスglycoprotein Mの詳細な解析2009
- Author(s)
  定岡知彦、山西弘一、森康子
- Organizer
  第24回ヘルペスウイルス研究会
- Place of Presentation
  静岡県裾野市
- Data Source
  KAKENHI-PROJECT-20790363
[Presentation] 水痘帯状疱疹ウイルスglycoprotein Mの成熟機構の解析2009
- Author(s)
  定岡知彦、山西弘一、森康子
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  東京都千代田区
- Data Source
  KAKENHI-PROJECT-20790363
[Presentation] VZV glycoprotein M and glycoprotein N assist each other for their functions2009
- Author(s)
  Tetsuo Koshizuka, Tomohiko Sadaoka, Hironori Yoshii, Koichi Yamanishi, Yasuko Mori
- Organizer
  14th International Conference on Immunobiology and Prophylaxis of Human Herpesvirus Infections
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-20790363
[Presentation] 水痘帯状庖疹ウイルスglycoprotein Mの詳細な解析2009
- Author(s)
  定岡知彦、山西弘一、森康子
- Organizer
  第24回ヘルペスウイルス研究会
- Place of Presentation
  富士教育研修所(静岡県)
- Data Source
  KAKENHI-PROJECT-20790363
[Presentation] Newly identified mRNA arisen from VZV ORF50 gene region was not essential for viral growth.2009
- Author(s)
  Tomohiko Sadaoka, Koichi Yamanishi, Yasuko Mori
- Organizer
  34^<th> International Herpesvirus Workshop
- Place of Presentation
  Ithaca, New York, USA
- Data Source
  KAKENHI-PROJECT-20790363
[Presentation] 水痘帯状疱疹ウイルスORF49と結合するウイルス性因子の同定及び解析2008
- Author(s)
  定岡知彦、林麻佑子、山西弘一、森康子
- Organizer
  第56回日本ウイルス学会学術集会
- Place of Presentation
  岡山県岡山市
- Data Source
  KAKENHI-PROJECT-20790363
[Presentation] Newly identified posttranscriptional regulation in the ORF50 gene which encodes glycoprotein M2008
- Author(s)
  Tomohiko Sadaoka, Yoshiaki Yamagishi, Koichi Yamanishi, Yasuko Mori
- Organizer
  International herpesvirus workshop(33rd)
- Place of Presentation
  Estoril, Portugal
- Data Source
  KAKENHI-PROJECT-20790363
[Presentation] Newly identified posttranscriptional regulation in ORF50 gene which encodes glycoprotein M2008
- Author(s)
  Tetsuo Koshizuka, Tomohiko Sadaoka, Hironori Yoshii, Koichi Yamanishi, Yasuko Mori
- Organizer
  33rd International Herpesvirus Workshop IHW
- Place of Presentation
  Estoril, Portugal
- Data Source
  KAKENHI-PROJECT-20790363
[Presentation] 水痘帯状疱疹ウイルスORF49と結合するウイルス性因子の同定および解析2008
- Author(s)
  定岡知彦、林麻佑子、山西弘一、森康子
- Organizer
  第56回日本ウイルス学会学術集会
- Place of Presentation
  岡山県岡山市
- Data Source
  KAKENHI-PROJECT-20790363

1. 美島健二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 安原理佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 田中準一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sadaoka Tomohiko 定岡 知彦

SADAOKA Tomohiko 定岡 知彦

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水痘帯状疱疹ウイルス感染性ウイルス粒子放出機構の解明Principal Investigator

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Investigation of varicella-zoster virus latency and reactivation mechanismPrincipal Investigator

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Molecular machanism of varicella-zoster vaccine virus attenuationPrincipal Investigator

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宿主・ウイルス間ヘテロトランススプライシング遺伝子発現制御による共生機構の解明Principal Investigator

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水痘帯状疱疹ウイルス新規遺伝子産物を標的とした潜伏感染機構の解明Principal Investigator

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Functional analysis of varicella-zoster virus ORF49 and ORF44Principal Investigator

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Functional analysis of Varicella-zoster virus encoding ORF49Principal Investigator

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[Book] Varicella-zoster vrus glycoprotein M(Current topics in microbiology and immunology, vol.342)2010

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[Journal Article] Author Correction: Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication2023

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[Journal Article] Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication.2022

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[Journal Article] A Variant Allele in Varicella-Zoster Virus Glycoprotein B Selected during Production of the Varicella Vaccine Contributes to Its Attenuation2022

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[Journal Article] Mutagenesis of the Varicella-Zoster Virus Genome Demonstrates That VLT and VLT-ORF63 Proteins Are Dispensable for Lytic Infection2021

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[Journal Article] Nectin-1 Is an Entry Mediator for Varicella-Zoster Virus Infection of Human Neurons2021

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[Journal Article] Epstein-Barr virus tegument protein BGLF2 suppresses type I IFN signaling to promote EBV reactivation2020

Author(s)

Sadaoka Tomohiko 定岡知彦

SADAOKA Tomohiko 定岡知彦