Shimasaki Miyako 島崎都

… Alternative Names

SHIMASAKI Miyako 島崎都

SHIMAZAKI Miyako 島崎都

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Researcher Number	00440511
Other IDs
Affiliation (Current)	2025: 金沢医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 金沢医科大学, 医学部, 准教授 2020 – 2023: 金沢医科大学, 医学部, 講師 2019: 金沢医科大学, 医学部, 助教 2016: 金沢医科大学, 医学部, 助教 2012: 金沢医科大学, 医学部, 助教 2008 – 2010: 金沢医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Human pathology Except Principal Investigator Human pathology / Basic Section 56020:Orthopedics-related / Basic Section 55040:Respiratory surgery-related / Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator 遺伝子プロファイリング / 遺伝子パスウェイ / RNA-sequencing / 大腿骨頭壊死 / 間葉系幹細胞 / ステロイド / 分化 / デキサメタゾン / 骨髄由来間葉系幹細胞 / 虚血プレコンディショニング … More / アポトーシス / 分化能 / 抗炎症作用 / 低酸素 / 酸化ストレス / 骨髄由来間葉系幹細胞(MSC9 / AQP / micropapillary / siRNA / トランスフェクション / HT1080細胞 / 浸潤能 / 細胞移動能 / AQP1 / 微小乳頭状成分 / 肺癌 … More Except Principal Investigator 浸潤・転移 / 間葉系幹細胞 / 細胞増殖 / 細胞移動 / EMT / 扁平上皮癌 / 肺癌 / 骨壊死 / ステロイド / Klotho / AKT経路 / 上皮間葉転換 / トランスフォーミング増殖因子β / 抗老化ホルモン / SOX2 / 原発性肺癌 / 超音波ドプラー / 血管病理 / 超音波ドプラ法 / 甲状腺濾胞性腫瘍 / 軟骨保護 / 疼痛抑制 / Homing / RNA sequencing / 変形性関節症 / 関節炎モデル / 軟骨損傷 / CXCL12/CXCR4 / モノヨード酢酸 / 軟骨 / ホーミング / 骨髄間葉系幹細胞 / 上皮間葉移行 / Sphingosin-1 phosphate / Sphingosin kinase-1 / Sphigolipid / 非小細胞性肺癌 / SMS-1, 2 / S1PR-1, 2, 3, 5 / SpK-1 / 細胞膜リン脂質 / 非小細胞生肺癌 / Sphyngomyelinase / Sphingosine-1-p受容体 / Sphingosin kinase 1 / 肺腺癌 / 細胞膜スフィンゴ脂質 / トランスフェクション / HT1080 / 浸潤能 / 細胞移動能 / 免疫組織化学 / 偽細胞突起 / 転移 / 移動・浸潤能 / 細胞分化 / Aquaporin 5 / Aquaporin 1 / 自然転移動物モデル / 遺伝子導入 / 自然肺転移実験動物モデル / 遺伝子発現修飾 / 軟部肉腫 / 骨肉腫 / アクアポリン / cDNA array / Snail / 上皮間質転換 EMT / Laser captured microddisection / プラコグロビン / TGFβ / 上皮間質転換 / HMGA2 Less

Development of a novel preventive method for steroid-induced osteonecrosis -Factors involved in mesenchymal stem cell dysfunction-
- Principal Investigator
  
  市堰徹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kanazawa Medical University
抗老化遺伝子KlothoのTGF-βを介した肺扁平上皮癌機能調節と治療開発のための基礎研究
- Principal Investigator
  
  飯島慶仁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kanazawa Medical University
Angiopathologic Approach to Differentiation of Benign and Malignant Follicular Tumors of the Thyroid by Ultrasound Doppler Technique
- Principal Investigator
  
  川上理
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kanazawa Medical University
Elucidate the molecular mechanism of pain suppression and cartilage protection by mesenchymal stem cells in a rabbit arthritis model
- Principal Investigator
  
  ICHISEKI Toru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kanazawa Medical University
Study on the molecular mechanism of prevention of steroid-induced osteonecrosis of the femur by intravenous administration of mesenchymal stem cellsPrincipal Investigator
- Principal Investigator
  
  SHIMASAKI Miyako
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kanazawa Medical University
Is sphingolipid of the cell membrane involved in invasion and metastasis of adenocarcinoma of the lung?
- Principal Investigator
  
  UEDA Yoshimichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kanazawa Medical University
Involvement and their roles of aquaporins in the metastasis and drug-resistance of bone and soft tissue sarcomas
- Principal Investigator
  
  UEDA Yoshimichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kanazawa Medical University
Investigation of molecular mechanism involved in the aggressiveness of micropapillary component of adenocarcinoma of lungPrincipal Investigator
- Principal Investigator
  
  SHIMASAKI Miyako
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Kanazawa Medical University
Analysis of activation mechanism of HMGA2 gene and its regulating gene-pathways in the progression of lung cancer
- Principal Investigator
  
  UEDA Yoshimichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kanazawa Medical University

All 2023 2022 2021 2020 2019 2016 2013 2012 2011 2010 2008

All Journal Article Presentation

[Journal Article] The Possibility of IPC to Prevent Ischemic-Reperfusion Injury in Skeletal Muscle in a Rat2023
- Author(s)
  Takanori Morikawa , Miyako Shimasaki, Toru Ichiseki , Shusuke Ueda, Yoshimichi Ueda, Kan Takahashi.
- Journal Title
  
  J Clin Med
  
  Volume: 12 Issue: 4 Pages: 1-13
- DOI
  10.3390/jcm12041501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18510
[Journal Article] Prognostic Impact of Sphingosine Kinase 1 in Nonsmall Cell Lung Cancer2021
- Author(s)
  Motono Nozomu、Ueda Yoshimichi、Shimasaki Miyako、Iwai Shun、Iijima Yoshihito、Usuda Katsuo、Uramoto Hidetaka
- Journal Title
  
  Clinical Pathology
  
  Volume: 14 Pages: 1-7
- DOI
  10.1177/2632010x20988531
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18226, KAKENHI-PROJECT-19K18510
[Journal Article] Resistance of bone marrow mesenchymal stem cells in a stressed environment - Comparison with osteocyte cells2021
- Author(s)
  Miyako Shimasaki , Shusuke Ueda , Toru Ichiseki , Hiroaki Hirata , Norio Kawahara , Yoshimichi Ueda.
- Journal Title
  
  International Journal of Medical Sciences
  
  Volume: 18 Issue: 6 Pages: 1375-1381
- DOI
  10.7150/ijms.52104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18510, KAKENHI-PROJECT-20K09513
[Journal Article] Glucocorticoid-induced osteocytic cell death in a hypoxic environment is associated with necroptosis2021
- Author(s)
  S.Ueda, T.Ichiseki, M.Shimasaki, H.Hirata, N.Kawahara, Y.Ueda
- Journal Title
  
  Bio Chem (ISSN: 2673-6411)
  
  Volume: 1 Issue: 2 Pages: 98-106
- DOI
  10.3390/biochem1020009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09513, KAKENHI-PROJECT-19K18510
[Journal Article] Mitochondrial transcription factor A added to osteocytes in a stressed environment has a cytoprotective effect2020
- Author(s)
  Shusuke Ueda, Miyako Shimasaki, Toru Ichiseki, Hiroaki Hirata, Norio kawahara, Yoshimichi Ueda
- Journal Title
  
  International Journal of Medical Sciences
  
  Volume: 17 Issue: 9 Pages: 1293-1299
- DOI
  10.7150/ijms.45335
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18510
[Journal Article] Relationship of aquaporin 1, 3 and 5 expression in lung cancer cells to cellular differentiation, invasive growth and metastasis potential2011
- Author(s)
  Yuichiro Machida, Miyako Shimasaki, et al.
- Journal Title
  
  Hum Pathol 42
  
  Pages: 669-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790369
[Journal Article] Relationship of aquaporin 1,3 and 5 expression in lung cancer cells to cellular differentiation,invasive growth and metastasis potential2011
- Author(s)
  Yuichiro Machida,Yoshimichi Ueda,Miyako Shimasaki,Katsuaki Sato,Shogo Katsuda,Tsutomu Sakuma
- Journal Title
  
  HumPatho
  
  Volume: l42 Pages: 669-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590323
[Journal Article] がん浸潤・転移の分子機構.2010
- Author(s)
  上田善道、島崎都、佐藤勝明、勝田省吾
- Journal Title
  
  検査と技術
  
  Volume: 38 Pages: 1192-3
- Data Source
  KAKENHI-PROJECT-22590323
[Journal Article] Aquaporin as a novel player in cancer cell invasion.2010
- Author(s)
  YoshimichiUeda,MiyakoShimasaki、他8名
- Journal Title
  
  Kanazawa Med
  
  Volume: J35 Pages: 61-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590323
[Journal Article] Aquaporin as a novel player in cancer cell invasion2010
- Author(s)
  Yoshimichi Ueda, Miyako Shimasaki, et al.
- Journal Title
  
  Kanazawa Med J 35巻
  
  Pages: 61-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790369
[Journal Article] 肺癌病理の Up to Date2008
- Author(s)
  上田善道、島崎都、東光太郎、Giafei Guo 、佐藤勝明、佐川元保、佐久間勉、勝田省吾
- Journal Title
  
  金沢医大雑誌 21
  
  Pages: 21-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590370
[Journal Article] Identification of novel genes involved in the synergistic antitumor effect of caffeine in osteosarcoma cells using cDNA macroarray.2008
- Author(s)
  Sadao Ii, Yoshimichi Ueda, Miyako Shimasaki, Shogo Katsuta, Koutarou Takazawa, Yoshimitsu Kanazawa, Katsuro Tomita, Hiroyuki Tsyuchiya.
- Journal Title
  
  Anticancer Res 28
  
  Pages: 645-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590370
[Journal Article] Down regulation of plakoglobin in soft tissue sarcoma is associated with a higher risk of pulmonary metastasis.2008
- Author(s)
  Yoshimitsu Kanazawa, Yoshimichi Ueda, Miyako Shimasaki, Shogo Katsuda, Norio Yamamto, Katsuo Tomita,Hiroyuki Tsuchiya.
- Journal Title
  
  Anticancer Res 28
  
  Pages: 655-664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590370
[Presentation] デキサメタゾン/低酸素によるストレス耐性は骨髄由来ラット間葉系幹細胞の骨芽細胞分化能を増強させる2023
- Author(s)
  島崎　都
- Organizer
  第112回日本病理学会
- Data Source
  KAKENHI-PROJECT-19K18510
[Presentation] ラット骨格筋における虚血プレコンディショニングの機序と月齢による影響2022
- Author(s)
  島崎　都
- Organizer
  第111回日本病理学会
- Data Source
  KAKENHI-PROJECT-19K18510
[Presentation] Taurine Inhibits Glucocorticoid-Induced Bone Mitochondrial Injury, Preventing Osteonecrosis in Rabbits and Cultured Osteocytes2021
- Author(s)
  島崎　都
- Organizer
  110回日本病理学会
- Data Source
  KAKENHI-PROJECT-19K18510
[Presentation] 間葉系組織幹細胞の細胞傷害性ストレスに対する in vitroでの機能解析2019
- Author(s)
  島崎　都
- Organizer
  第１０８回日本病理学会
- Data Source
  KAKENHI-PROJECT-19K18510
[Presentation] Sphingosin kinase 1の発現はヒト口腔癌と非小細胞生肺癌がん細胞の EMTに関係する2016
- Author(s)
  島崎　都、上田善道
- Organizer
  第11回スフィンゴテラピイ研究会
- Place of Presentation
  ホテルアローレ（石川県加賀市）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-26460442
[Presentation] 軟部肉腫におけるアクアポリン15の発現とその意義2013
- Author(s)
  島崎都、上田善道、他
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22590323
[Presentation] 軟部肉腫におけるアクアポリン1,5の発現とその意義2012
- Author(s)
  島崎都、上田善道、他
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590323
[Presentation] Relationship of aquaporin 1, 3 and 5 expression in lung cancer cells to cellular differentiation, invasive growth and metastasis potential2011
- Author(s)
  Miyako Shimazaki
- Organizer
  Congress of European Respiratory Society 2011
- Place of Presentation
  Amsterdam, Holland
- Data Source
  KAKENHI-PROJECT-22590323
[Presentation] Relationship of aquapor in1,3 and 5 expression in lung cancer cells tocellular differentiation,invasive growth and metastasis potential.2011
- Author(s)
  MiyakoShimasaki,YoshimichiUeda,他
- Organizer
  Congress of European Respiratory Society
- Place of Presentation
  Amsterdam,Holland
- Data Source
  KAKENHI-PROJECT-22590323
[Presentation] 軟部肉腫におけるアクアポリン1,5の発現とその意義2011
- Author(s)
  島崎都
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京(京王プラザホテル)
- Data Source
  KAKENHI-PROJECT-22590323
[Presentation] 骨肉腫におけるアクアポリン1,5の発現と肺転移への関与2011
- Author(s)
  島崎都、上田善道,他
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-22590323
[Presentation] 肺微小乳頭micropapillaryadenocarcinomaの侵襲性に関わる遺伝子群の検索2010
- Author(s)
  島崎都
- Organizer
  第99回日本病理学会
- Place of Presentation
  東京都新宿区京王プラザホテル
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-21790369
[Presentation] Down regulation of plakoglobin in soft tissue sarcoma is associated with a higher risk of pulmonary metastasis.2008
- Author(s)
  Yoshimitsu Kanazawa , Yoshimichi Ueda , Miyako Shimasaki, Shogo Katsuda, Norio Yamamto, Katsuo Tomita,Hiroyuki Tsuchiya
- Organizer
  The 8^<th>International Conference of Anticancer Research
- Place of Presentation
  in Kos, Greece
- Data Source
  KAKENHI-PROJECT-19590370
[Presentation] Identific-ation of Novel Genes Involved in the Synergistic Antitumor Effect of Caffeine in Osteosarcoma Cells Using cDNA Macroarray.2008
- Author(s)
  Sadao Ii, Yoshimichi Ueda, Miyako Shimasaki, Shogo Katsuta, Koutarou Takazawa, Yoshimitsu Kanazawa, Katsuro Tomita, Hiroyuki Tsyuchiya
- Organizer
  The 8^<th>International Conference of Anticancer Research
- Place of Presentation
  in Kos, Greece
- Data Source
  KAKENHI-PROJECT-19590370
[Presentation] ヒト軟部肉腫における新規肺転移抑制遺伝子human plakoglobin遺伝子の同定2008
- Author(s)
  島崎都、上田善道、佐藤勝明、勝田省吾
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-19590370

1. UEDA Yoshimichi (50271375)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
2. ICHISEKI Toru (30307631)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. SAGAWA Motoyasu (70292274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. TSUCHIYA Hiroyuki (40227434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OKAZAKI Toshirou (40233308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 川上理 (10807142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 北村守正 (60543262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 下出祐造 (60319043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 飯島慶仁 (70409184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 本野望 (30634901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 浦本秀隆 (90389445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山田壮亮 (90525453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 植田修右 (10759583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 熊谷泉那 (70791820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Shimasaki Miyako 島崎 都

SHIMASAKI Miyako 島崎 都

SHIMAZAKI Miyako 島崎 都

Research Projects

Research Products

Co-Researchers

Development of a novel preventive method for steroid-induced osteonecrosis -Factors involved in mesenchymal stem cell dysfunction-

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

抗老化遺伝子KlothoのTGF-βを介した肺扁平上皮癌機能調節と治療開発のための基礎研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Angiopathologic Approach to Differentiation of Benign and Malignant Follicular Tumors of the Thyroid by Ultrasound Doppler Technique

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidate the molecular mechanism of pain suppression and cartilage protection by mesenchymal stem cells in a rabbit arthritis model

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the molecular mechanism of prevention of steroid-induced osteonecrosis of the femur by intravenous administration of mesenchymal stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Is sphingolipid of the cell membrane involved in invasion and metastasis of adenocarcinoma of the lung?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement and their roles of aquaporins in the metastasis and drug-resistance of bone and soft tissue sarcomas

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of molecular mechanism involved in the aggressiveness of micropapillary component of adenocarcinoma of lungPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of activation mechanism of HMGA2 gene and its regulating gene-pathways in the progression of lung cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Possibility of IPC to Prevent Ischemic-Reperfusion Injury in Skeletal Muscle in a Rat2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic Impact of Sphingosine Kinase 1 in Nonsmall Cell Lung Cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Resistance of bone marrow mesenchymal stem cells in a stressed environment - Comparison with osteocyte cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glucocorticoid-induced osteocytic cell death in a hypoxic environment is associated with necroptosis2021

Author(s)

Journal Title

DOI

Data Source

Shimasaki Miyako 島崎都

SHIMASAKI Miyako 島崎都

SHIMAZAKI Miyako 島崎都