Shitamukai Atsunori 下向敦範

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SHITAMUKAI Atsunori 下向敦範

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Researcher Number	00442971
Other IDs	https://orcid.org/0000-0003-4216-927X
Affiliation (Current)	2025: 岡山大学, 医歯薬学域, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 岡山大学, 医歯薬学域, 講師 2018 – 2021: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 専門職研究員 2016 – 2017: 国立研究開発法人理化学研究所, 多細胞システム形成研究センター, 専門職研究員 2013: 独立行政法人理化学研究所, 発生・再生科学総合研究センター, 専門職研究員 2012: 独立行政法人理化学研究所, 非対称細胞分裂研究グループ, 専門職研究員
Review Section/Research Field	Principal Investigator Basic Section 48010:Anatomy-related / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 46010:Neuroscience-general-related
Keywords	Principal Investigator 脳発生 / 神経幹細胞 / 脳の肥厚化 / 細胞多様性 / mRNAターゲティング / RNA / Cas13 / 分子スイッチ / 発生・分化 / 脳・神経 … More / 上皮構造 / シグナル伝達 / 細胞内輸送 / ライブイメージング / FGF signaling / self-renewal / radial glia / neural stem cell / フィードバックシグナル / 神経層形成 / 自己複製 / 神経 … More Except Principal Investigator 神経幹細胞 / 再生医学 / 液性因子 / 皮質下投射ニューロン / 大脳皮質形成 / エピゲノム / 微小カラム / 大脳新皮質 / 光遺伝学 / 脳微小カラム Less

神経上皮構造の復元力減少による脳の局所的肥厚化メカニズムの解明Principal Investigator
- Principal Investigator
  
  下向敦範
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Okayama University
細胞治療のための液性因子作用局所化による人工合成ニッチの開発
- Principal Investigator
  
  川口綾乃
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Okayama University
1細胞空間エピゲノム解析による大脳新皮質微小カラム構造形成機構の解明
- Principal Investigator
  
  今野大治郎
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Kindai University
Development of RNA dependent protein switches and application to neuroscience.Principal Investigator
- Principal Investigator
  
  Shitamukai Atsunori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Institute of Physical and Chemical Research
Role of feedback signaling from neurons to neural stem cells in mammalian developing brain.Principal Investigator
- Principal Investigator
  
  Shitamukai Atsunori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Institute of Physical and Chemical Research
The feedback signaling from neurons to neural stem cellsPrincipal Investigator
- Principal Investigator
  
  SHITAMUKAI Atsunori
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Institute of Physical and Chemical Research

All 2020 2019 2016 2014 2013 2012

All Journal Article Presentation Book

[Book] Mammalian Development: Networks, Switches, and Morphogenetic Processes, SECTION II. MORPHOGENETIC PROCESSES, 8 Cell Division Modes and Cleavage Planes of Neural Progenitors during Mammalian Cortical Development2013
- Author(s)
  Fumio Matsuzaki, Atsunori Shitamukai
- Total Pages
  520
- Publisher
  Cold Spring Harbor Laboratory Press
- Data Source
  KAKENHI-PROJECT-24700361
[Book] Atsunori Shitamukai, Mammalian Development : Networks, Switches, and Morphogenetic Processes, SECTION II. MORPHOGENETIC PROCESSES, 8 Cell Division Modes and Cleavage Planes of Neural Progenitors during Mammalian Cortical Development2013
- Author(s)
  Fumio Matsuzaki, Atsunori Shitamukai
- Publisher
  Cold Spring Harbor Laboratory Press
- Data Source
  KAKENHI-PROJECT-24700361
[Journal Article] Notch1 and Notch2 collaboratively maintain radial glial cells in mouse neurogenesis2020
- Author(s)
  Mase Shun、Shitamukai Atsunori、Wu Quan、Morimoto Mitsuru、Gridley Thomas、Matsuzaki Fumio
- Journal Title
  
  Neuroscience Research
  
  Volume: Available online 11 December Pages: 1-11
- DOI
  10.1016/j.neures.2020.11.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22441, KAKENHI-PUBLICLY-19H04791, KAKENHI-PROJECT-18K14722, KAKENHI-PROJECT-18H04003
[Journal Article] Endfoot regeneration restricts radial glial state and prevents translocation into the outer subventricular zone in early mammalian brain development2019
- Author(s)
  Fujita Ikumi、Shitamukai Atsunori、Kusumoto Fumiya、Mase Shun、Suetsugu Taeko、Omori Ayaka、Kato Kagayaki、Abe Takaya、Shioi Go、Konno Daijiro、Matsuzaki Fumio
- Journal Title
  
  Nature Cell Biology
  
  Volume: 22 Issue: 1 Pages: 26-37
- DOI
  10.1038/s41556-019-0436-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06272, KAKENHI-PROJECT-18K14828, KAKENHI-PROJECT-19K22441, KAKENHI-PUBLICLY-19H04791, KAKENHI-PROJECT-18H04003, KAKENHI-PUBLICLY-17H05779
[Journal Article] Developing a De Novo Targeted Knock-in Method Based on in Utero Electroporation Into the Mammalian Brain2016
- Author(s)
  Tsunekawa, Yuji, Raymond Kunikane Terhune, Ikumi Fujita, Atsunori Shitamukai, Taeko Suetsugu, Fumio Matsuzaki
- Journal Title
  
  Development
  
  Volume: 143 Issue: 17 Pages: 3216-3222
- DOI
  10.1242/dev.136325
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K18381, KAKENHI-PROJECT-16K18382, KAKENHI-PROJECT-16K21627
[Journal Article] Novel and robust transplantation reveals the acquisition of polarized processes by cortical cells derived from mouse and human pluripotent stem cells2014
- Author(s)
  Fumiaki Nagashima, Ikuo K Suzuki, Atsunori Shitamukai, Haruko Sakaguchi, Misato Iwashita, Taeko Kobayashi, Shigenobu Tone, Kazunori Toida, Pierre Vanderhaeghen, Yoichi Kosodo
- Journal Title
  
  Stem cells and development
  
  Volume: (in press) Issue: 18 Pages: 2129-2142
- DOI
  10.1089/scd.2013.0251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700361, KAKENHI-PUBLICLY-25112511, KAKENHI-PROJECT-26440122
[Journal Article] Improving spinning disk confocal microscopy by preventing pinhole cross-talk for intravital imaging.2013
- Author(s)
  Togo Shimozawa et al.
- Journal Title
  
  Proceeding of the National Academy of Sciences of the United States of America
  
  Volume: 110 Issue: 9 Pages: 3399-3404
- DOI
  10.1073/pnas.1216696110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370072, KAKENHI-PLANNED-24113006, KAKENHI-PROJECT-24500395, KAKENHI-PROJECT-24700361, KAKENHI-PLANNED-20114007, KAKENHI-PUBLICLY-24116708
[Journal Article] Evidence of Antagonistic Regulation of Restart from G<sub>1</sub> Delay in Response to Osmotic Stress by the Hog1 and Whi3 in Budding Yeast2013
- Author(s)
  Masaki Mizunuma, Takafumi Ogawa, Tetsuya Koyama, Atsunori Shitamukai, Ryohei Tsubakiyama, Tadamasa Komaruyama, Toshinaga Yamaguchi, Kazunori Kume and Dai Hirata
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 77 Issue: 10 Pages: 2002-2007
- DOI
  10.1271/bbb.130260
- NAID
  130003381877
- ISSN
  0916-8451, 1347-6947
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J06992, KAKENHI-PROJECT-24380057, KAKENHI-PROJECT-24580142, KAKENHI-PROJECT-24700361
[Journal Article] cAMP/cAMP-dependent Protein Kinase (PKA) Regulates Multiple Aspects of Cellular Events by Phosphorylating the Whi3 Cell Cycle Regulator in Budding Yeast2013
- Author(s)
  M. Mizunuma, R. Tsubakiyama, T. Ogawa, A. Shitamukai, Y. Kobayashi, T. Inai, K. Kume, and D. Hirata
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 288(in press) Issue: 15 Pages: 10558-10566
- DOI
  10.1074/jbc.m112.402214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J06992, KAKENHI-PROJECT-24380057, KAKENHI-PROJECT-24580142, KAKENHI-PROJECT-24700361
[Journal Article] Amplification of progenitors in the mammalian telencephalon includes a new radial glial cell type.2013
- Author(s)
  Pilz GA, Shitamukai A, Reillo I, Pacary E, Schwausch J, Stahl R, Ninkovic J, Snippert HJ, Clevers H, Godinho L, Guillemot F, Borrell V, Matsuzaki F, Götz M.
- Journal Title
  
  Nat Commun.
  
  Volume: 4 Issue: 1 Pages: 2125-2125
- DOI
  10.1038/ncomms3125
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24113006, KAKENHI-PROJECT-24700361
[Journal Article] Control of asymmetric cell division of mammalian neural progenitors2012
- Author(s)
  Atsunori Shitamukai, Fumio Matsuzaki
- Journal Title
  
  Dev. Growth Differ
  
  Volume: 54 Issue: 3 Pages: 277-286
- DOI
  10.1111/j.1440-169x.2012.01345.x
- NAID
  10031136901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700361, KAKENHI-ORGANIZER-24113001
[Presentation] 神経幹細胞のradial fiberは自己複製能維持のためのシグナル伝達分子の輸送の場として機能する2016
- Author(s)
  下向敦範、今野大治郎、下郡智美、後藤明弘、高田慎治、松田道行、松崎文雄
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-16K18381
[Presentation] Live imaging of the developing brain2014
- Author(s)
  下向敦範
- Organizer
  第7回神経発生討論会
- Place of Presentation
  大阪府,吹田市,大阪大学吹田キャンパス銀杏会館
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] Live imaging of the developing brain2014
- Author(s)
  下向敦範、松崎文雄
- Organizer
  第7回神経発生討論会
- Place of Presentation
  大阪府、吹田市、大阪大学　吹田キャンパス　銀杏会館
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] Spatial and temporal control of signaling pathways for neural stem cell self-renewal in the developing mammalian brain.2013
- Author(s)
  Atsunori Shitamukai, Akihiro Goto, Michiyuki Matsuda, Fumio Matsuzaki
- Organizer
  第46回日本発生生物学会
- Place of Presentation
  島根県、松江市、くにびきメッセ
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] Spatial and temporal control of signaling pathways for neural stem cell self-renewal in the developing mammalian brain2013
- Author(s)
  Atsunori Shitamukai
- Organizer
  第46回日本発生生物学会
- Place of Presentation
  島根県,松江市,くにびきメッセ
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] 神経幹細胞の自己複製能を維持するシグナルの空間的制御2013
- Author(s)
  下向敦範
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都府,京都市,国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] 神経幹細胞の自己複製能を維持するシグナルの空間的制御2013
- Author(s)
  下向敦範、後藤明弘、松田道行、松崎文雄
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都府、京都市、国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] 神経幹細胞の自己複製能を維持するシグナルの時空間的制御2012
- Author(s)
  下向敦範、後藤明弘、松田道行、松崎文雄
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡県、福岡市、福岡国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] Roles of the epithelial structure in the neural progenitor self-renewal in the mammalian developing brain2012
- Author(s)
  Atsunori Shitamukai
- Organizer
  第45回日本発生生物学会・第64回日本細胞生物学会合同大会
- Place of Presentation
  兵庫県,神戸市,神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] 神経幹細胞の自己複製能を維持するシグナルの時空間的制御2012
- Author(s)
  下向敦範
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡県,福岡市,福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] マウス神経幹細胞の自己複製能における上皮構造の役割2012
- Author(s)
  下向敦範、今野大治朗、松崎文雄
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  愛知県、名古屋市、名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] Roles of the epithelial structure in the neural progenitor self-renewal in the mammalian developing brain.2012
- Author(s)
  Atsunori Shitamukai, Daijiro Konno, Fumio Matsuzaki
- Organizer
  第45回日本発生生物学会･第64回日本細胞生物学会合同大会
- Place of Presentation
  兵庫県、神戸市、神戸国際会議場
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] Roles of the epithelial structure in the neural progenitor self-renewal in the mammalian developing neocortex2012
- Author(s)
  Atsunori Shitamukai
- Organizer
  4th International Conference on Stem Cell and Tissue Formation
- Place of Presentation
  ドイツ,ドレスデン,マックスプランク研究所
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] Roles of the epithelial structure in the neural progenitor self-renewal in the mammalian developing neocortex.2012
- Author(s)
  Atsunori Shitamukai, Daijiro Konno, Fumio Matsuzaki
- Organizer
  4th International Conference on Stem Cell and Tissue Formation
- Place of Presentation
  ドイツ、ドレスデン、マックスプランク研究所
- Data Source
  KAKENHI-PROJECT-24700361
[Presentation] マウス神経幹細胞の自己複製能における上皮構造の役割2012
- Author(s)
  下向敦範
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  愛知県,名古屋市,名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-24700361

1. 今野大治郎 (00362715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 丸岡久人 (60443032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 川口綾乃 (90360528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松崎文雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 加藤輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shitamukai Atsunori 下向 敦範

SHITAMUKAI Atsunori 下向 敦範

Research Projects

Research Products

Co-Researchers

神経上皮構造の復元力減少による脳の局所的肥厚化メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞治療のための液性因子作用局所化による人工合成ニッチの開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

1細胞空間エピゲノム解析による大脳新皮質微小カラム構造形成機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of RNA dependent protein switches and application to neuroscience.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of feedback signaling from neurons to neural stem cells in mammalian developing brain.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The feedback signaling from neurons to neural stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Mammalian Development: Networks, Switches, and Morphogenetic Processes, SECTION II. MORPHOGENETIC PROCESSES, 8 Cell Division Modes and Cleavage Planes of Neural Progenitors during Mammalian Cortical Development2013

Author(s)

Total Pages

Publisher

Data Source

[Book] Atsunori Shitamukai, Mammalian Development : Networks, Switches, and Morphogenetic Processes, SECTION II. MORPHOGENETIC PROCESSES, 8 Cell Division Modes and Cleavage Planes of Neural Progenitors during Mammalian Cortical Development2013

Author(s)

Publisher

Data Source

[Journal Article] Notch1 and Notch2 collaboratively maintain radial glial cells in mouse neurogenesis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endfoot regeneration restricts radial glial state and prevents translocation into the outer subventricular zone in early mammalian brain development2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Developing a De Novo Targeted Knock-in Method Based on in Utero Electroporation Into the Mammalian Brain2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel and robust transplantation reveals the acquisition of polarized processes by cortical cells derived from mouse and human pluripotent stem cells2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Improving spinning disk confocal microscopy by preventing pinhole cross-talk for intravital imaging.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evidence of Antagonistic Regulation of Restart from G<sub>1</sub> Delay in Response to Osmotic Stress by the Hog1 and Whi3 in Budding Yeast2013

Author(s)

Journal Title

DOI

NAID

Shitamukai Atsunori 下向敦範

SHITAMUKAI Atsunori 下向敦範