ZHAO Xiangdong 趙向東

Researcher Number	00444464
Affiliation (based on the past Project Information) *help	2018 – 2022: 京都大学, ウイルス・再生医科学研究所, 特定助教 2011 – 2013: 京都大学, 医学(系)研究科(研究院), 助教 2008 – 2011: Kyoto University, 医学研究科, 助教 2010: 京都大学, 医学研究科, 特定助教 2010: Kyoto University, 大学院・医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / General surgery Except Principal Investigator Thoracic surgery / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator 制御性Ｔ細胞 / 制御性T細胞 / 免疫抑制 / マウス / 免疫寛容 / 肝移植 / 外科 / トランスレーショナルリサーチ / 移植・再生医療 / 臓器保存 … More Except Principal Investigator … More 肺保存 / がん / 肝内胆管がん / 腫瘍浸潤リンパ球 / 癌免疫 / 肝内胆管癌 / 線維化 / 臟器保存液 / 低温潅流保存 / 血再灌流障害 / 外科 / トランスレーショナルリサーチ / 移植・再生医療 / 呼吸器外科 / Impulse Oscillation System / ラット肺移植 / 冷保存 / 慢性拒絶反応 / 急性拒絶反応 / 肺移植 / 強制オッシレーション法 / lung mechanical property / FOT Less

Analysis of fibrosis of cancer stroma in the hepatobiliary and pancreatic tumors.
- Principal Investigator
  
  Iwaisako Keiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Doshisha University
制御性T細胞による免疫抑制療法　ーマウス肝移植モデルを用いた検討ーPrincipal Investigator
- Principal Investigator
  
  趙向東
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyoto University
Pre-clinical study on pulmonary perfusion preservation using modified ET-Kyoto solutions
- Principal Investigator
  
  BANDO TORU
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kyoto University
ドナー肺の長時間低温保存における至適保存方法検討
- Principal Investigator
  
  藤永卓司
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kyoto University
Development of a method for simultaneous multiple thoracic and abdominal organ procurement using ET-Kyoto solutionPrincipal Investigator
- Principal Investigator
  
  ZHAO Xiangdong
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
Basic research for evaluating the donor lung mechanical properties using FOT (Forced Oscillation Technique)
- Principal Investigator
  
  SAKAI Hiroaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kyoto University

All 2022 2021 2019 2012 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] In situ vaccination using unique TLR9 ligand K3-SPG induces long-lasting systemic immune response and synergizes with systemic and local immunotherapy2022
- Author(s)
  Okada H, Takahashi K, Yaku H, Kobiyama K, Iwaisako K, Zhao X, Shiokawa M, Uza N, Kodama Y, Ishii KJ, Seno H.
- Journal Title
  
  Sci Rep.
  
  Volume: 12 Issue: 1 Pages: 2132-2132
- DOI
  10.1038/s41598-022-05702-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03659, KAKENHI-PROJECT-20K08996, KAKENHI-PROJECT-21K20802, KAKENHI-PROJECT-20K08329
[Journal Article] Complement-5 Inhibition Deters Progression of Fulminant Hepatitis to Acute Liver Failure in Murine Models2021
- Author(s)
  Kusakabe J, Hata K, Miyauchi H, Tajima T, Wang Y, Tamaki I, Kawasoe J, Okamura Y, Zhao X, Okamoto T, Tsuruyama T, Uemoto S.
- Journal Title
  
  Cell Mol Gastroenterol Hepatol.
  
  Volume: 21 Issue: 5 Pages: 1351-1367
- DOI
  10.1016/j.jcmgh.2021.01.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08538
[Journal Article] The effect of beta-2 adrenoreceptor agonist inhalation on lungs donated after cardiac death in a canine lung transplantation model.2012
- Author(s)
  Sakamoto J, Chen F, Nakajima D, Yamada T, Ohsumi A, Zhao X, Sakai H, Bando T, Date H.
- Journal Title
  
  J Heart Lung Transplant
  
  Volume: 31 Pages: 773-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592056
[Journal Article] The effect of beta-2 adrenoreceptor agonost inhalation on lungs donated after cardiac death in a canine lung transplantation model2012
- Author(s)
  Sakamoto J, Chen F, Nakajima D, Yamada T, Ohsumi A, Zhao X, Sakai H, Bando T, Date H
- Journal Title
  
  J Heart Lung Transplant
  
  Volume: 31 Pages: 773-779
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592056
[Journal Article] Effects of preprocurement ventilation on lungs donated after cardiac death in a canine lung transplantation model2011
- Author(s)
  Sakamoto J, Chen F, Yamada T, Nakajima D, Ohsumi A, Kikuchi R, Zhao X, Fujinaga T, Shoji T, Sakai H, Bando T, Date H
- Journal Title
  
  Transplantation
  
  Volume: 92 Pages: 864-870
- NAID
  120004995874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592056
[Journal Article] Effects of preprocurement ventilation on lungs donated after cardiac death in a canine lung transplantation model.2011
- Author(s)
  Sakamoto J, Chen F, Yamada T, Nakajima D, Ohsumi A, Kikuchi R, Zhao X, Fujinaga T, Shoji T, Sakai H, Bando T, Date H
- Journal Title
  
  Transplantation
  
  Volume: 92 Pages: 864-870
- NAID
  120004995874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592056
[Journal Article] Comprehensive and innovative techniques for liver transplantation in rats : a surgical guide.2010
- Author(s)
  Hori T, Nguyen JH, Zhao X, Ogura Y, Hata T, Yagi S, Chen F, Baine AM, Ohashi N, Eckman CB, Herdt AR, Egawa H, Takada Y, Oike F, Sakamoto S, Kasahara M, Ogawa K, Hata K, Iida T, Yonekawa Y, Sibulesky L, Kuribayashi K, Kato T, Saito K, Wang L, Torii M, Sahara N, Kamo N, Sahara T, Yasutomi M, Uemoto S.
- Journal Title
  
  World J Gastroenterol. 16(25)
  
  Pages: 3120-3132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591522
[Journal Article] The generation of donor-specific CD4+CD25++CD45RA+ naive regulatory T cells in operationally tolerant patients after pediatric living-donor liver transplantation.2010
- Author(s)
  Nafady-Hego H, Li Y, Ohe H, Zhao X, Satoda N, Sakaguchi S, Wood K, Uemoto S, Koshiba T.
- Journal Title
  
  Transplantation 90(12)
  
  Pages: 1547-1555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591522
[Journal Article] Nebulized phosphodiesterase III inhibitor during warm ischemia attenuates pulmonary ischemia-reperfusion injury.2009
- Author(s)
  Zhang J, Chen F, Zhao X, Aoyama A, Okamoto T, Fujinaga T, Shoji T, Sakai H, Cui Y, Bando T, Date H.
- Journal Title
  
  J Heart Lung Transplant. 28(1)
  
  Pages: 79-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591522
[Journal Article] Nebulized phosphodiesterase III inhibitor during warm ischemia attenuates pulmonary ischemia-reperfusion injury.2009
- Author(s)
  Zhang J, Chen F, Zhao X, Aoyama A, Okamoto T, Fujinaga T, Shoji T, Sakai H, Cui Y, Bando T, Date H
- Journal Title
  
  J Heart Lung Transplant 28(1)
  
  Pages: 79-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591667
[Journal Article] Requirement of protocol biopsy before and after complete cessation of immunosuppression following liver transplantation.2009
- Author(s)
  Yoshitomi M, Koshiba T, Haga H, Li Y, Zhao X, Cheng D, Miyagawa A, Sakashita H, Tsuruyama T, Ueda M, Okamoto S, Wood K, Sakaguchi S, Manabe T, Uemoto S.
- Journal Title
  
  Transplantation 87(4)
  
  Pages: 606-614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591522
[Journal Article] ET-Kyoto solution plus Dibutyryl Adenosine Monophosphate is Superior to University of Wisconsin Solution in Rat Liver Preservation.2008
- Author(s)
  Zhao X, Koshiba T, Nakamura T, Tsuruyama T, Li Y, Bnado T, Wada H, Tanaka K.
- Journal Title
  
  Cell Transplant 17
  
  Pages: 99-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591522
[Journal Article] Value of FOXP3 expression in peripheral blood as rejection marker after miniature swine lung transplantation.2008
- Author(s)
  Satoda N, Shoji T, Wu Y, Fijinaga T, Chen F, Aoyama A, Zhang J, Takahashi A, Okamoto T, Matsumoto I, Sakai H, Li Y, Zhao X, Manabe T, Kobayashi E, Sakaguchi S, Wada H, Uemoto S, Tottori J, Bando T, Date H, Koshiba T.
- Journal Title
  
  J Heart Lung Transplant 27(12)
  
  Pages: 1293-1301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591522
[Journal Article] Value of Foxp3 expression in peripheral blood as rejection marker after miniature swine lung transplantation.2008
- Author(s)
  Satoda N, Shoji T, Wu Y, Fuijnaga T, Chen F, Aoyama A, Zhang JT, Takahashi A, Okamoto T, Matsumoto I, Sakai H, Li Y, Zhao X, Manabe T, Kobayashi E, Sakaguchi S, Wada H, Uemoto S, Tottori J, Bando T, Date H, Koshiba T
- Journal Title
  
  J Heart Lung Transplant 27(12)
  
  Pages: 1293-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591667
[Presentation] Oral administration of IgA attenuates cholestatoc liver injury via microbiota modulation in mice. AASLD The Liver Meeting, 2021/11/12-15, 国外, ポスター.2021
- Author(s)
  Tsushima H, Zhao X, Ohkubo S, Hatano E, Shinkura R, Iwaisako K.
- Organizer
  AASLD The Liver Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08996
[Presentation] 外科医が行う臓器保存の研究とその副次的効果2021
- Author(s)
  金光瑛彰、趙向東、祝迫惠子、八木真太郎、萩原正敏
- Organizer
  第121回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K08996
[Presentation] RECONSTRUCTION OF THE HEPATIC ARTERY IN MOUSE LIVER TRANSPLANTATION2019
- Author(s)
  Keiko Iwaisako, Xiangdong Zhao, Masataka Asagiri, Takashi Ito, Hiroaki Fuji, Junji Uehori, Noriko Sakaguchi, Shimon Sakaguchi, Shinji Uemoto
- Organizer
  DDW (Digestive Disease Week) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08538
[Presentation] ET-Kyoto液を使用した肺移植症例の検討2011
- Author(s)
  藤永卓司、中島大輔、阪本仁、趙向東、佐藤寿彦、陳豊史、庄司剛、園部誠、阪井宏彰、板東徹、伊達洋至
- Organizer
  京都臓器保存セミナー
- Place of Presentation
  京都市
- Year and Date
  2011-03-19
- Data Source
  KAKENHI-PROJECT-20591522
[Presentation] Prolonged Rat Kidney Preservation with ET-Kyoto Solution : Comparison with Histidine-Tryptophan-Ketoglutarate and University of Wisconsin Solutions.2011
- Author(s)
  Zhao X, Fujinaga T, Li Y, Bando T, Wada H, Date H
- Organizer
  American Transplant Congress 2011
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-20591522
[Presentation] Beta2-adrenoreceptor agonist inhalation ameliorates ischemia reperfusion injury following lung transplantation from non-heart-beating donors in a canine model2011
- Author(s)
  Jin Sakamoto, Fengshi Chen, Daisuke Nakajima, Tetsu Yamada, Akihiro Ohsumi, Xiangdong Zhao, Takuji Fujinaga, Tsuyoshi Shoji, Hiroaki Sakai, Toru Bando, Hiroshi Date
- Organizer
  Congress of the Asian Society of Transplantation 2011
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-23592056
[Presentation] Beta2-adrenoreceptor agonist inhalation ameliorates ischemia reperfusion injury following lung transplantation from non-heart-beating donors in a canine model2011
- Author(s)
  Jin Sakamoto, Fengshi Chen, Daisuke Nakajima, Tetsu Yamada, Akihiro Ohsumi, Xiangdong Zhao, Takuji Fujinaga, Tsuyoshi Shoji, Hiroaki Sakai, Toru Bando, Hiroshi Date
- Organizer
  The 15th European Society for Organ Transplantation Congress
- Place of Presentation
  Glasgow, UK
- Data Source
  KAKENHI-PROJECT-23592056
[Presentation] ET-Kyoto液の開発と臓器機能保存学講座5年の歩み。2011
- Author(s)
  板東徹、和田洋巳、中村隆之、藤永卓司、陳豊史、趙向東、大角明宏、中島大輔、阪本仁、庄司剛、阪井宏彰、伊達洋至
- Organizer
  京都臓器保存セミナー
- Place of Presentation
  京都
- Year and Date
  2011-03-19
- Data Source
  KAKENHI-PROJECT-20591522
[Presentation] ラット腎保存におけるET-Kyoto液とhistidine-tryptophan-ketoglutarate液及びUniversity of Wisconsin液の比較2010
- Author(s)
  趙向東
- Organizer
  第46回日本移植学会総会
- Place of Presentation
  みやこめっせ(京都市)(招待講演)
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-20591522
[Presentation] ラット腎保存におけるET-Kyoto液とhistidine-tryptophan-ketoglutarate液およびUniversity of Wisconsin液の比較2010
- Author(s)
  趙向東, 藤永卓司, 陳豊史, 板東徹, 和田洋巳, 伊達洋至
- Organizer
  第46回日本移植学会総会
- Place of Presentation
  京都市
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-20591522
[Presentation] 臓器保存の現状と将来の展望肺移植における肺保存の現状と新たな肺保存方法の検討2010
- Author(s)
  藤永卓司, 中島大輔, 阪本仁, 趙向東, 陳豊史, 庄司剛, 阪井宏彰, 板東徹, 伊達洋至
- Organizer
  第37回日本臓器保存生物医学会学術集会
- Place of Presentation
  新潟市
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-20591522
[Presentation] Evaluation of Lung Mechanics in Acute Lung Allograft Rejection in Rats, Using Forced Oscillation Technique (FOT)2008
- Author(s)
  A.Takahashi, H.Sakai, X.Zhao, M.D., H.Hamakawa, T.Okamoto, N. Satoda, A. Aoyama, J. Zhang, F. Chen, T. Fujinaga, T. Shoji, T. Bando, H. Wada, H. Date
- Organizer
  ATS
- Place of Presentation
  Poster Discussion Session, USA
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-20591667
[Presentation] Evaluation of lung mechanics on acute allograft rejection in a rat single lung transplant model using forced oscillation technique (FOT) ERS Vienna 2009 Congress2008
- Author(s)
  A.Takahashi, H.Sakai, Zhao X, H.Date, et al
- Organizer
  New Surgical Approach for COPD : Covering Lung with an Elastic Net ATS.(T.Sato, H.Sakai, A.Takahashi, H.Date, T.Nakamura)
- Place of Presentation
  Mini-Symposium, Vienna
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-20591667

1. FUJINAGA Takuji (00444456)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
2. DATE Hiroshi (60252962)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
3. BANDO Toru (20293954)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. Iwaisako Keiko (70625300)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 黄政龍 (10271511)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. CHEN Fengshi (00452334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. SAKAI Hiroaki (50362489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. AOYAMA Akihiro (60379047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SATO Masaaki (00623109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 瀬尾智 (70646546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 坂東徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 13 results
12. 妹尾浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ZHAO Xiangdong 趙 向東

Research Projects

Research Products

Co-Researchers

Analysis of fibrosis of cancer stroma in the hepatobiliary and pancreatic tumors.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

制御性T細胞による免疫抑制療法 ーマウス肝移植モデルを用いた検討ーPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pre-clinical study on pulmonary perfusion preservation using modified ET-Kyoto solutions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ドナー肺の長時間低温保存における至適保存方法検討

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a method for simultaneous multiple thoracic and abdominal organ procurement using ET-Kyoto solutionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic research for evaluating the donor lung mechanical properties using FOT (Forced Oscillation Technique)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] In situ vaccination using unique TLR9 ligand K3-SPG induces long-lasting systemic immune response and synergizes with systemic and local immunotherapy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Complement-5 Inhibition Deters Progression of Fulminant Hepatitis to Acute Liver Failure in Murine Models2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The effect of beta-2 adrenoreceptor agonist inhalation on lungs donated after cardiac death in a canine lung transplantation model.2012

Author(s)

Journal Title

Data Source

[Journal Article] The effect of beta-2 adrenoreceptor agonost inhalation on lungs donated after cardiac death in a canine lung transplantation model2012

Author(s)

Journal Title

Data Source

[Journal Article] Effects of preprocurement ventilation on lungs donated after cardiac death in a canine lung transplantation model2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Effects of preprocurement ventilation on lungs donated after cardiac death in a canine lung transplantation model.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Comprehensive and innovative techniques for liver transplantation in rats : a surgical guide.2010

Author(s)

Journal Title

Data Source

[Journal Article] The generation of donor-specific CD4+CD25++CD45RA+ naive regulatory T cells in operationally tolerant patients after pediatric living-donor liver transplantation.2010

Author(s)

Journal Title

Data Source

[Journal Article] Nebulized phosphodiesterase III inhibitor during warm ischemia attenuates pulmonary ischemia-reperfusion injury.2009

Author(s)

Journal Title

Data Source

ZHAO Xiangdong 趙向東

制御性T細胞による免疫抑制療法　ーマウス肝移植モデルを用いた検討ーPrincipal Investigator