YAMAMOTO Masahiro 山本雅裕

Researcher Number	00444521
Other IDs
Affiliation (Current)	2025: 大阪大学, 微生物病研究所, 教授
Affiliation (based on the past Project Information) *help	2013 – 2024: 大阪大学, 微生物病研究所, 教授 2012: 大阪大学, 微生物病研究所, 准教授 2010 – 2011: Osaka University, 医学系研究科, 准教授 2007 – 2009: Osaka University, 医学系研究科, 助教 2008: Osaka University, 医学系研究科, 助教授
Review Section/Research Field	Principal Investigator Biological Sciences / Immunology / Parasitology (including sanitary zoology) / Transformative Research Areas, Section (III) / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Biological Sciences / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Pathology, Infection/Immunology, and related fields Except Principal Investigator Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 42020:Veterinary medical science-related / Parasitology (including sanitary zoology)
Keywords	Principal Investigator トキソプラズマ / インターフェロン / 寄生胞 / トキソプラズマ原虫 / 寄生胞膜 / 細胞自律的免疫系 / GBP2 / 病原性因子 / インターフェロンγ / 自然免疫 … More / 転写因子 / シグナル伝達 / PLAMP / 宿主免疫系 / IRGB6 / GBP / 細胞内膜 / 病原性 / 中国 / 病原体 / RabGDIa / GRA6 / NFAT4 / 原虫 / IFN-γ / 原虫感染免疫 / TLR / 疾患特異的 / 正常組織 / VeDTR / マクロファージ / セルオートノマス免疫 / UIS3 / マラリア原虫 / 非自己 / 自己 / ライフサイクル / マネジメント / 生きた病原体 / 新しいパターン / ブタ / CRISPRスクリーン / 家畜病原体 / 炎症性疾患 / インターフェロン誘導性GTPase / IFN誘導性GTPase / ネオノンセルフ / PI5P / 北東アジア / 武漢株Ａ / 系統解析 / 日本株 / 韓国株 / 中国株 / 共同研究 / 韓国 / 細菌感染 / Caspase-11 / 非標準的NLRP3インフラマソーム / 非標準的インフラマソーム / サルモネラ / グラム陰性菌 / Caspasse-11 / パイロトーシス / 免疫 / ユビキチン / 遺伝子多様性 / 遺伝子多型 / アミノ酸多型 / 免疫抑制 / インターフェロンガンマ / 病原体含有膜 / GTP分解酵素 / 膜破壊機構 / 病原体形成空胞 / 細胞死 / 非標準ピロプトーシス / RabGDIα / 抗原提示 / キラーT細胞 / ES細胞 / Stat3 / ROP16 / エフェクター機構 / オートファジー / 免疫系 / ATF6β / ROP18 / 自然免疫系 / T細胞分化 / 自己免疫疾患 / 核内タンパク質 / 遺伝学 / 自然免疫学 / 分子遺伝学 / 細胞内寄生性原虫 / シグナル伝達経路 … More Except Principal Investigator トキソプラズマ / 感染感受性 / 宿主域 / コウモリ / 免疫 / 人獣共通感染症 / 野生動物 / ワクチン / インフラマトリーモノサイト / CCR2 / 先天性トキソプラズマ症 / 活性化 / シスト / 潜伏 / ネオスポラ / Sabin-Feldman dye test / HIV感染者 / 色素試験 / 血清学的検査 / HIV感染 / エゾジカ / 血清学的診断法 / 感染症 / ゲノム / 生態学 / 微生物 / 寄生 / 共生 / オルガネラ / 進化 Less

新規先天性トキソプラズマ症モデルマウスによるその予防法の開発
- Principal Investigator
  
  神山長慶
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Oita University
Development of novel normal and disease-specific macrophage depletion method using VeDTR mouse systemPrincipal Investigator
- Principal Investigator
  
  山本雅裕
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Osaka University
致死性病原体の潜伏を可能にする野生動物の分子免疫機構
- Principal Investigator
  
  高島康弘
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Gifu University
Establishment of PLAMP as a new concept to determine self and nonself for obligatory intracellular pathogensArea Organizer
- Area Organizer
  
  山本雅裕
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
Management of PLAMP researchPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO MASAHIRO
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Osaka University
Elucidation of protozoan PLAMP generation mechanism recognized by host cell-autonomous immunityPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO MASAHIRO
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Osaka University
The molecular mechanisms of Toxoplasma gondii and Neospora caninum reactivation from latency.
- Principal Investigator
  
  Takashima Yasuhiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Gifu University
Physiological mechanisms to maintain self and nonself on intracellular membranes, and its pathological failurePrincipal Investigator
- Principal Investigator
  
  山本雅裕
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Elucidation of interferon-dependent host defense system against legal infectious disease-causing microbes for domestic animalsPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO MASAHIRO
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Osaka University
Pathogenic and genetic analysis of Toxoplasma by Japan, China and South KoreaPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Masahiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Osaka University
Elucidation of novel mechanism to discriminate intracellular membranes using Toxoplasma gondiiPrincipal Investigator
- Principal Investigator
  
  Yamamoto Masahiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pathology, Infection/Immunology, and related fields
- Research Institution
  Osaka University
細菌含有膜破壊によるパイロトーシス誘導・制御メカニズムの解明Principal Investigator
- Principal Investigator
  
  山本雅裕
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Development of novel serodiagnostic method for the detection of active toxoplasmosis
- Principal Investigator
  
  Hoshina Tokio
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Jikei University School of Medicine
マトリョーシカ型進化原理の展開
- Principal Investigator
  
  野崎智義
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  National Institute of Infectious Diseases
Development of the highly efficient Toxoplasma anti-tumor vaccinePrincipal Investigator
- Principal Investigator
  
  Yamamoto Masahiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Osaka University
CRISPRゲノム編集法によるCaspase-11依存的パイロトーシスの解析Principal Investigator
- Principal Investigator
  
  山本雅裕
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Analysis of IFN-inducible GTPase-dependent cell-autonomous immunityPrincipal Investigator
- Principal Investigator
  
  Yamamoto Masahiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
Analysis of Chinese Toxoplasma phylogeny and virulencePrincipal Investigator
- Principal Investigator
  
  Yamamoto Masahiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Osaka University
「寄生胞」を介したトキソプラズマ―宿主間相互支配の“力学”の解明Principal Investigator
- Principal Investigator
  
  山本雅裕
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Development of the in vitro maintenance system for undifferentiated stem cells using Toxoplasma ROP16Principal Investigator
- Principal Investigator
  
  YAMAMOTO Masahiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Osaka University
トキソプラズマ原虫「寄生胞」をめぐる寄生体・宿主間の攻防の解明Principal Investigator
- Principal Investigator
  
  山本雅裕
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Elucidation of novel innate immune system by analysis of host-parasite interactionPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Masahiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
原虫による宿主免疫抑制機構の解析Principal Investigator
- Principal Investigator
  
  山本雅裕
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Role of a nuclear protein IκBζ in innate immunityPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Masahiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
細胞内寄生性原虫の感染防御機構Principal Investigator
- Principal Investigator
  
  山本雅裕
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Analysis of the mechanisms for innate immune responses to microbesPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Masahiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University

[Journal Article] Host genetics highlights IFN-γ-dependent Toxoplasma genes encoding secreted and non-secreted virulence factors in in?vivo CRISPR screens2023
- Author(s)
  Tachibana Yuta、Hashizaki Emi、Sasai Miwa、Yamamoto Masahiro
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 6 Pages: 112592-112592
- DOI
  10.1016/j.celrep.2023.112592
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KJ1469, KAKENHI-ORGANIZER-20H05770, KAKENHI-PLANNED-20H05771, KAKENHI-PROJECT-19H00970
[Journal Article] Toxoplasma IWS1 Determines Fitness in Interferon-γ-Activated Host Cells and Mice by Indirectly Regulating ROP18 mRNA Expression.2023
- Author(s)
  Hashizaki Emi、Sasai Miwa、Okuzaki Daisuke、Nishi Tsubasa、Kobayashi Takashi、Iwanaga Shiroh、Yamamoto Masahiro
- Journal Title
  
  mBio
  
  Volume: 14 Issue: 1
- DOI
  10.1128/mbio.03256-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-22K19434, KAKENHI-PROJECT-21KK0137, KAKENHI-PROJECT-20H03477, KAKENHI-PROJECT-17H04649, KAKENHI-PLANNED-20H05771, KAKENHI-PROJECT-19H00970, KAKENHI-PROJECT-18H02642, KAKENHI-PROJECT-21K06986, KAKENHI-PROJECT-23K27671
[Journal Article] A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity2023
- Author(s)
  Okamoto Masaaki、Sasai Miwa、Kuratani Ayumi、Okuzaki Daisuke、Arai Masaya、Wing James B.、Sakaguchi Shimon、Yamamoto Masahiro
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 7 Pages: 112813-112813
- DOI
  10.1016/j.celrep.2023.112813
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-20H05770, KAKENHI-PLANNED-20H05771, KAKENHI-PROJECT-19H00970, KAKENHI-PROJECT-23K27671
[Journal Article] Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells2021
- Author(s)
  Sasai Miwa、Ma Ji Su、Okamoto Masaaki、Nishino Kohei、Nagaoka Hikaru、Takashima Eizo、Pradipta Ariel、Lee Youngae、Kosako Hidetaka、Suh Pann-Ghill、Yamamoto Masahiro
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 218 Issue: 7
- DOI
  10.1084/jem.20201763
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05771, KAKENHI-PROJECT-19H00970, KAKENHI-PROJECT-18H02642
[Journal Article] High resistance to Toxoplasma gondii infection in inducible nitric oxide synthase knockout rats2021
- Author(s)
  Wang Zhen-Jie、Yu Shao-Meng、Gao Jiang-Mei、Zhang Peng、Hide Geoff、Yamamoto Masahiro、Lai De-Hua、Lun Zhao-Rong
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 11 Pages: 103280-103280
- DOI
  10.1016/j.isci.2021.103280
- Data Source
  KAKENHI-PROJECT-18KK0226
[Journal Article] Cell-autonomous <i>Toxoplasma</i> killing program requires Irgm2 but not its microbe vacuolar localization2021
- Author(s)
  Pradipta Ariel、Sasai Miwa、Motani Kou、Ma Ji Su、Lee Youngae、Kosako Hidetaka、Yamamoto Masahiro
- Journal Title
  
  Life Science Alliance
  
  Volume: 4 Issue: 7 Pages: e202000960-e202000960
- DOI
  10.26508/lsa.202000960
- NAID
  120007185166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05771, KAKENHI-PROJECT-19H00970, KAKENHI-PROJECT-20K07340, KAKENHI-PROJECT-18H02642
[Journal Article] Plasmodium UIS3 avoids host cell-autonomous exclusion that requires GABARAPs but not LC3 and autophagy2021
- Author(s)
  Pradipta Ariel、Bando Hironori、Ma Ji Su、Tanaka Shun、Sasai Miwa、Yamamoto Masahiro
- Journal Title
  
  Parasitology International
  
  Volume: 83 Pages: 102335-102335
- DOI
  10.1016/j.parint.2021.102335
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20H05771, KAKENHI-PROJECT-19H00970
[Journal Article] T cell-derived interferon-γ is required for host defense to2020
- Author(s)
  Nishiyama Saishi、Pradipta Ariel、Ma Ji Su、Sasai Miwa、Yamamoto Masahiro
- Journal Title
  
  Parasitology International
  
  Volume: 75 Pages: 102049-102049
- DOI
  10.1016/j.parint.2019.102049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0226, KAKENHI-PROJECT-18H02642
[Journal Article] Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic Shock2020
- Author(s)
  Sakaguchi Naoya、Sasai Miwa、Bando Hironori、Lee Youngae、Pradipta Ariel、Ma Ji Su、Yamamoto Masahiro
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 561948-561948
- DOI
  10.3389/fimmu.2020.561948
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16628, KAKENHI-PUBLICLY-19H04809
[Journal Article] Initial phospholipid-dependent Irgb6 targeting to Toxoplasma gondii vacuoles mediates host defense.2019
- Author(s)
  Lee, Y., Yamada, H., Pradipta, A., Ma, J.S., Okamoto, M., Nagaoka, H., Takashima, E., Standley, D.M., Sasai, M., Takei, K., Yamamoto, M.
- Journal Title
  
  Life Science Alliance
  
  Volume: 3 Issue: 1 Pages: 000-000
- DOI
  10.26508/lsa.201900549
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07084, KAKENHI-PROJECT-18KK0226, KAKENHI-PROJECT-19H00970, KAKENHI-PROJECT-18H02430, KAKENHI-PROJECT-18H02642, KAKENHI-PROJECT-19H03225, KAKENHI-PROJECT-17K08808, KAKENHI-PROJECT-18K05970, KAKENHI-PROJECT-18K15135, KAKENHI-PUBLICLY-19H04809
[Journal Article] Toxoplasma Effector GRA15-Dependent Suppression of IFN-γ-Induced Antiparasitic Response in Human Neurons2019
- Author(s)
  Bando Hironori、Lee Youngae、Sakaguchi Naoya、Pradipta Ariel、Sakamoto Ryoma、Tanaka Shun、Ma Ji Su、Sasai Miwa、Yamamoto Masahiro
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 9 Pages: 140-140
- DOI
  10.3389/fcimb.2019.00140
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16628, KAKENHI-PROJECT-18KK0226, KAKENHI-PUBLICLY-19H04809, KAKENHI-PROJECT-19H00970, KAKENHI-PROJECT-18H02642, KAKENHI-PROJECT-18K15135
[Journal Article] CXCR4 regulates Plasmodium development in mouse and human hepatocytes2019
- Author(s)
  Bando Hironori、Pradipta Ariel、Iwanaga Shiroh、Okamoto Toru、Okuzaki Daisuke、Tanaka Shun、Vega-Rodr?guez Joel、Lee Youngae、Ma Ji Su、Sakaguchi Naoya、Soga Akira、Fukumoto Shinya、Sasai Miwa、Matsuura Yoshiharu、Yuda Masao、Jacobs-Lorena Marcelo、Yamamoto Masahiro
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 216 Issue: 8 Pages: 1733-1748
- DOI
  10.1084/jem.20182227
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22527, KAKENHI-PROJECT-18KK0226, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-19H04809, KAKENHI-PROJECT-19H00970, KAKENHI-PROJECT-17H04071, KAKENHI-PROJECT-18H02642, KAKENHI-PROJECT-18K15135, KAKENHI-PROJECT-19K15973, KAKENHI-PROJECT-17H01542
[Journal Article] Toxoplasma Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human Cells2018
- Author(s)
  Bando Hironori、Sakaguchi Naoya、Lee Youngae、Pradipta Ariel、Ma Ji Su、Tanaka Shun、Lai De-Hua、Liu Jianfa、Lun Zhao-Rong、Nishikawa Yoshifumi、Sasai Miwa、Yamamoto Masahiro
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 2073-2073
- DOI
  10.3389/fimmu.2018.02073
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05970, KAKENHI-PROJECT-18K15135, KAKENHI-PROJECT-18KK0226, KAKENHI-PUBLICLY-17H05507, KAKENHI-PROJECT-18H02642, KAKENHI-PROJECT-17K19538, KAKENHI-PROJECT-17K19556, KAKENHI-PROJECT-17K15677, KAKENHI-PROJECT-15H05275
[Journal Article] Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa2018
- Author(s)
  Balakrishnan Arjun、Karki Rajendra、Berwin Brent、Yamamoto Masahiro、Kanneganti Thirumala-Devi
- Journal Title
  
  Cell Death Discovery
  
  Volume: 4 Issue: 1 Pages: 3-3
- DOI
  10.1038/s41420-018-0068-z
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05507
[Journal Article] A Nonpyroptotic IFN-γ?Triggered Cell Death Mechanism in Nonphagocytic Cells PromotesSalmonellaClearance In Vivo2018
- Author(s)
  Ingram Justin P.、Tursi Sarah、Zhang Ting、Guo Wei、Yin Chaoran、A. Wynosky-Dolfi Meghan、van der Heijden Joris、Cai Kathy Q.、Yamamoto Masahiro、Finlay B. Brett、Brodsky Igor E.、Grivennikov Sergei I.、T?kel ?agla、Balachandran Siddharth
- Journal Title
  
  The Journal of Immunology
  
  Volume: 200 Issue: 10 Pages: 3626-3634
- DOI
  10.4049/jimmunol.1701386
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05507, KAKENHI-PROJECT-17K19556
[Journal Article] Host immune responses to Toxoplasma gondii2018
- Author(s)
  Sasai Miwa、Pradipta Ariel、Yamamoto Masahiro
- Journal Title
  
  International Immunology
  
  Volume: 30 Issue: 3 Pages: 113-119
- DOI
  10.1093/intimm/dxy004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19556, KAKENHI-PROJECT-15H04745
[Journal Article] Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response2018
- Author(s)
  Bando Hironori、Lee Youngae、Sakaguchi Naoya、Pradipta Ariel、Ma Ji Su、Tanaka Shun、Cai Yihong、Liu Jianfa、Shen Jilong、Nishikawa Yoshifumi、Sasai Miwa、Yamamoto Masahiro
- Journal Title
  
  mBio
  
  Volume: 9 Issue: 5 Pages: 5-5
- DOI
  10.1128/mbio.01738-18
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05970, KAKENHI-PROJECT-18K15135, KAKENHI-PROJECT-18KK0226, KAKENHI-PUBLICLY-17H05507, KAKENHI-PROJECT-18H02642, KAKENHI-PROJECT-17K19538, KAKENHI-PROJECT-17K19556, KAKENHI-PROJECT-17K15677, KAKENHI-PROJECT-15H05275
[Journal Article] Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection2018
- Author(s)
  Briard Benoit、Karki Rajendra、Malireddi R. K. Subbarao、Bhattacharya Anannya、Place David E.、Mavuluri Jayadev、Peters Jennifer L.、Vogel Peter、Yamamoto Masahiro、Kanneganti Thirumala-Devi
- Journal Title
  
  Nature Microbiology
  
  Volume: 4 Issue: 2 Pages: 316-327
- DOI
  10.1038/s41564-018-0298-0
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05507, KAKENHI-PROJECT-17K19556
[Journal Article] GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections2018
- Author(s)
  Kim Jin Kyung、Kim Yi Sak、Lee Hye-Mi、Jin Hyo Sun、Neupane Chiranjivi、Kim Sup、Lee Sang-Hee、Min Jung-Joon、Sasai Miwa、Jeong Jae-Ho、Choe Seong-Kyu、Kim Jin-Man、Yamamoto Masahiro、Choy Hyon E.、Park Jin Bong、Jo Eun-Kyeong
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 4184-4184
- DOI
  10.1038/s41467-018-06487-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02642, KAKENHI-PROJECT-17K19556
[Journal Article] Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense2017
- Author(s)
  Sasai Miwa、Sakaguchi Naoya、Ma Ji Su、Nakamura Shuhei、Kawabata Tsuyoshi、Bando Hironori、Lee Youngae、Saitoh Tatsuya、Akira Shizuo、Iwasaki Akiko、Standley Daron M、Yoshimori Tamotsu、Yamamoto Masahiro
- Journal Title
  
  Nature Immunology
  
  Volume: 18 Issue: 8 Pages: 899-910
- DOI
  10.1038/ni.3767
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19556, KAKENHI-PROJECT-26713005, KAKENHI-PUBLICLY-17H05507, KAKENHI-PUBLICLY-17H05533, KAKENHI-PUBLICLY-17H06009, KAKENHI-PLANNED-17H06415, KAKENHI-PLANNED-25111002, KAKENHI-PROJECT-15H04745, KAKENHI-PROJECT-17H05064, KAKENHI-PROJECT-16K19116, KAKENHI-PROJECT-16K19153
[Journal Article] Characterization of SPP inhibitors suppressing propagation of HCV and protozoa2017
- Author(s)
  Hirano J, Okamoto T, Sugiyama Y, Suzuki T, Kusakabe S, Tokunaga M, Fukuhara T, Sasai M, Tougan T, Matsunaga Y, Yamashita K, Sakai Y, Yamamoto M, Horii T, Standley DM, Moriishi K, Moriya K, Koike K, Matsuura Y.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 114 Issue: 50
- DOI
  10.1073/pnas.1712484114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08759, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-15H04745
[Journal Article] IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.2016
- Author(s)
  Man SM, Karki R, Sasai M, Place DE, Kesavardhana S, Temirov J, Frase S, Zhu Q, Malireddi RK, Kuriakose T, Peters JL, Neale G, Brown SA, Yamamoto M, Kanneganti TD.
- Journal Title
  
  Cell
  
  Volume: 167 Pages: 382-396
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04745
[Journal Article] IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.2016
- Author(s)
  Man SM, Karki R, Sasai M, Place DE, Kesavardhana S, Temirov J, Frase S, Zhu Q, Malireddi RK, Kuriakose T, Peters JL, Neale G, Brown SA, Yamamoto M, Kanneganti TD.
- Journal Title
  
  Cell.
  
  Volume: 167 Pages: 382-396
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-WRAPUP-16H01703
[Journal Article] IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.2016
- Author(s)
  Man SM, Karki R, Sasai M, Place DE, Kesavardhana S, Temirov J, Frase S, Zhu Q, Malireddi RK, Kuriakose T, Peters JL, Neale G, Brown SA, Yamamoto M, Kanneganti TD.
- Journal Title
  
  Cell
  
  Volume: 167 Pages: 382-396
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15122
[Journal Article] IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.2016
- Author(s)
  Man SM, Karki R, Sasai M, Place DE, Kesavardhana S, Temirov J, Frase S, Zhu Q, Malireddi RK, Kuriakose T, Peters JL, Neale G, Brown SA, Yamamoto M, Kanneganti TD.
- Journal Title
  
  Cell
  
  Volume: 167 Pages: 382-396
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01377
[Journal Article] p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen.2015
- Author(s)
  Lee Y, Sasai M, Ma JS, Sakaguchi N, Ohshima J, Bando H, Saitoh T, Akira S, Yamamoto M
- Journal Title
  
  Cell Rep
  
  Volume: 13 Issue: 2 Pages: 223-233
- DOI
  10.1016/j.celrep.2015.09.005
- NAID
  120007001422
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14951, KAKENHI-PROJECT-15K15122, KAKENHI-PUBLICLY-15H01377, KAKENHI-PUBLICLY-15H01380, KAKENHI-PUBLICLY-26111514, KAKENHI-PROJECT-15H06382, KAKENHI-PROJECT-26713005
[Journal Article] RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.2015
- Author(s)
  Ohshima J, Sasai M, Liu J, Yamashita K, Ma JS, Lee Y, Bando H, Howard JC, Ebisu S, Hayashi M, Takeda K, Standley DM, Frickel EM, Yamamoto M.
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  Proc Natl Acad Sci U S A.
  
  Volume: 112 Issue: 33
- DOI
  10.1073/pnas.1510031112
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26117713, KAKENHI-PROJECT-15H04745, KAKENHI-PROJECT-15H06382
[Journal Article] Role of the mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii.2014
- Author(s)
  Ohshima J, Lee Y, Sasai M, Saitoh T, Ma JS, Kamiyama N, Matsuura Y, Pann-Ghill S, Hayashi M, Ebisu S, Takeda K, Akira S, Yamamoto M
- Journal Title
  
  J Immunol.
  
  Volume: 192 Pages: 3328-3335
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117512
[Journal Article] Role of the mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii.2014
- Author(s)
  Ohshima J, Lee Y, Sasai M, Saitoh T, Ma JS, Kamiyama N, Matsuura Y, Pann-Ghill S, Hayashi M, Ebisu S, Takeda K, Akira S, Yamamoto M
- Journal Title
  
  J Immunol.
  
  Volume: 192 Pages: 3328-3335
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26117713
[Journal Article] The E2-Like Conjugation Enzyme Atg3 Promotes Binding of IRG and Gbp Proteins to Chlamydia- and Toxoplasma-Containing Vacuoles and Host Resistance.2014
- Author(s)
  Haldar AK, Piro AS, Pilla DM, Yamamoto M, Coers J.
- Journal Title
  
  PLoS One
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689029
[Journal Article] Innate immune response induced by baculovirus attenuates transgene expression in mammalian cells.2014
- Author(s)
  Ono C, Ninomiya A, Yamamoto S, Abe T, Wen X, Fukuhara T, Sasai M, Yamamoto M, Saitoh T, Satoh T, Kawai T, Ishii KJ, Akira S, Okamoto T, Matsuura Y.
- Journal Title
  
  J Virol.
  
  Volume: 88 Pages: 2157-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689029
[Journal Article] Role of the mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii.2014
- Author(s)
  Ohshima J, Lee Y, Sasai M, Saitoh T, Ma JS, Kamiyama N, Matsuura Y, Pann-Ghill S, Hayashi M, Ebisu S, Takeda K, Akira S, Yamamoto M
- Journal Title
  
  J Immunol.
  
  Volume: 192 Pages: 3328-3335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670201
[Journal Article] Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS2014
- Author(s)
  Pilla DM, Hagar JA, Haldar AK, Mason AK, Degrandi D, Pfeffer K, Ernst RK, Yamamoto M, Miao EA, Coers J.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670201
[Journal Article] Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6.2014
- Author(s)
  Ma JS, Sasai M, Ohshima J, Lee Y, Bando H, Takeda K, Yamamoto M
- Journal Title
  
  J Exp Med.
  
  Volume: 211 Pages: 2013-2032
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670201
[Journal Article] Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6.2014
- Author(s)
  Ma JS, Sasai M, Ohshima J, Lee Y, Bando H, Takeda K, Yamamoto M
- Journal Title
  
  J Exp Med.
  
  Volume: 211 Pages: 2013-2032
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26117713
[Journal Article] Role of Mouse and Human Autophagy Proteins in IFN-γ-Induced Cell-Autonomous Responses against Thxoplasma gondii2014
- Author(s)
  Jun Ohshima, Youngae Lee, Miwa Sasai, Tatsuya Saitoh, Ji Su Ma, Naganori Kamiyama, Yoshiharu Matsuura, Suh Pann-Ghill, Mikako Hayashi, Shigeyuki Ebisu, Kiyoshi Takeda, Shizuo Akira, and Masahiro Yamamoto.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 192(7) Issue: 7 Pages: 3328-35
- DOI
  10.4049/jimmunol.1302822
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J01218, KAKENHI-PROJECT-23689029, KAKENHI-PROJECT-24790474, KAKENHI-PROJECT-24890106, KAKENHI-PUBLICLY-25117717, KAKENHI-PROJECT-25670027, KAKENHI-PUBLICLY-26111514, KAKENHI-PROJECT-26713005, KAKENHI-PROJECT-26860189
[Journal Article] Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.2014
- Author(s)
  Pilla DM, Hagar JA, Haldar AK, Mason AK, Degrandi D, Pfeffer K, Ernst RK, Yamamoto M, Miao EA, Coers J.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689029
[Journal Article] Innate immune response induced by baculovirus attenuates transgene expression in mammalian cells.2014
- Author(s)
  Ono C, Ninomiya A, Yamamoto S, Abe T, Wen X, Fukuhara T, Sasai M, Yamamoto M, Saitoh T, Satoh T, Kawai T, Ishii KJ, Akira S, Okamoto T, Matsuura Y.
- Journal Title
  
  J Virol.
  
  Volume: 88 Pages: 2157-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670201
[Journal Article] Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.2014
- Author(s)
  Meunier E, Dick MS, Dreier RF, Schurmann N, Broz DK, Warming S, Roose-Girma M, Bumann D, Kayagaki N, Takeda K, Yamamoto M, Broz P.
- Journal Title
  
  Nature
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670201
[Journal Article] Role of the mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii.2014
- Author(s)
  Ohshima J, Lee Y, Sasai M, Saitoh T, Ma JS, Kamiyama N, Matsuura Y, Pann-Ghill S, Hayashi M, Ebisu S, Takeda K, Akira S, Yamamoto M
- Journal Title
  
  J Immunol.
  
  Volume: 192 Pages: 3328-3335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689029
[Journal Article] The E2-Like Conjugation Enzyme Atg3 Promotes Binding of IRG and Gbp Proteins to Chlamydia- and Toxoplasma-Containing Vacuoles and Host Resistance.2014
- Author(s)
  Haldar AK, Piro AS, Pilla DM, Yamamoto M, Coers J.
- Journal Title
  
  PLoS One.
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670201
[Journal Article] Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.2014
- Author(s)
  Meunier E, Dick MS, Dreier RF, Schurmann N, Broz DK, Warming S, Roose-Girma M, Bumann D, Kayagaki N, Takeda K, Yamamoto M, Broz P.
- Journal Title
  
  Nature
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689029
[Journal Article] Pathogen Recognition Receptors: Ligands and Signaling Pathways by Toll-like Receptors.2013
- Author(s)
  Sasai M, Yamamoto M
- Journal Title
  
  Int Rev Immunol.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117512
[Journal Article] Pathogen Recognition Receptors: Ligands and Signaling Pathways by Toll-like Receptors.2013
- Author(s)
  Sasai M, Yamamoto M
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  Int Rev Immunol.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689029
[Journal Article] Subversion of host cellular functions by the apicomplexan parasites.2013
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  Kemp LE, Yamamoto M, Soldati-Favre D
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  FEMS Microbiol Rev.
  
  Volume: 印刷中 Issue: 4 Pages: 607-631
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  10.1111/1574-6976.12013
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117512
[Journal Article] A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii2012
- Author(s)
  Yamamoto M, Okuyama M, Ma JS, Kimura T, Kamiyama N, Saiga H, Ohshima J, Sasai M, Kayama H, Okamoto T, Huang DS, Soldati-Favre D, Horie K, Takeda J, Takeda K
- Journal Title
  
  Immunity
  
  Volume: 37 Pages: 302-313
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117512
[Journal Article] A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii.2012
- Author(s)
  Yamamoto M, Okuyama M, Ma JS, Kimura T, Kamiyama N, Saiga H, Ohshima J, Sasai M, Kayama H, Okamoto T, Huang DS, Soldati-Favre D, Horie K, Takeda J, Takeda K.
- Journal Title
  
  Immunity
  
  Volume: 37 Pages: 302-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689029
[Journal Article] Inhibition of ATF6β-dependent host adaptive immune response by a Toxoplasma virulence factor ROP182012
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  Yamamoto M, et al
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  Virulence
  
  Volume: 3 Pages: 1-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689029
[Journal Article] A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii2012
- Author(s)
  Yamamoto M, Okuyama M, Ma JS, Kimura T, Kamiyama N, Saiga H, Ohshima J, Sasai M, Kayama H, Okamoto T, Huang DS, Soldati-Favre D, Horie K, Takeda J, Takeda K
- Journal Title
  
  Immunity
  
  Volume: 37 Pages: 302-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689029
[Journal Article] ATF6βis a host cellular target of the Toxoplasma gondii virulence factor ROP182011
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  Yamamoto M, Ma JS, Mueller C, Kamiyama N, Saiga H, Kubo E, Kimura T, Okamoto T, Okuyama M, Kayama H, Nagamune K, Takashima S, Matsuura Y, Soldati-Favre D, Takeda K
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  J Exp Med
  
  Volume: 208 Issue: 1 Pages: 1533-1546
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  10.4161/viru.3.1.18340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689029
[Journal Article] ATF6β is a host cellular target of the Toxoplasma gondii virulence factor ROP182011
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  Yamamoto M, et al
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  J Exp Med
  
  Volume: 208 Pages: 1533-1546
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- Data Source
  KAKENHI-PROJECT-23689029
[Journal Article] Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice.2010
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  Burkhardt R, Toh SA, Lagor WR, Birkeland A, Levin M, Li X, Robblee M, Fedorov VD, Yamamoto M, Satoh T, Akira S, Kathiresan S, Breslow JL, Rader DJ.
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  J Clin Invest.
  
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  KAKENHI-PROJECT-21790467
[Journal Article] IkBz regulates Th17 development by cooperating with ROR nuclear receptors. Nature.2010
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  Okamoto K, Iwai Y, Oh-hora M, Yamamoto M, et al.
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  Nature. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790467
[Journal Article] Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice.2010
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  Burkhardt R, Toh SA, Lagor WR, Birkeland A, Levin M, Li X, Robblee M, Fedorov VD, Yamamoto M, Satoh T, Akira S, Kathiresan S, Breslow JL, Rader DJ.
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  J Clin Invest.
  
  Volume: 120 Pages: 4410-4
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022030
[Journal Article] IkBz regulates Th17 development by cooperating with ROR nuclear receptors.2010
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  Okamoto K, Iwai Y, Oh-hora M, Yamamoto M, et al.
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  Nature. 464
  
  Pages: 1381-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790467
[Journal Article] IkBz regulates Th17 development by cooperating with ROR nuclear receptors. Nature.2010
- Author(s)
  Okamoto K, Iwai Y, Oh-hora M, Yamamoto M, et al.
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  Nature.
  
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- Data Source
  KAKENHI-PUBLICLY-21022030
[Journal Article] IkBz regulates Th17 development by cooperating with ROR nuclear receptors. Nature.2010
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  Okamoto K, Iwai Y, Oh-hora M, Yamamoto M, et al.
- Journal Title
  
  Nature.
  
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- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790467
[Journal Article] IkBz regulates Th17 development by cooperating with ROR nuclear receptors. Nature.2010
- Author(s)
  Okamoto K, Iwai Y, Oh-hora M, Yamamoto M, et al.
- Journal Title
  
  Nature. (印刷中)
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- Data Source
  KAKENHI-PUBLICLY-21022030
[Journal Article] Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10.2010
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  Ueda Y, Kayama H, Jeon SG, Kusu T, Isaka Y, Rakugi H, Yamamoto M, Takeda K.
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  Int Immunol.
  
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- Data Source
  KAKENHI-PROJECT-21790467
[Journal Article] Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10.2010
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  Ueda Y, Kayama H, Jeon SG, Kusu T, Isaka Y, Rakugi H, Yamamoto M, Takeda K.
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  Int Immunol.
  
  Volume: 22 Pages: 953-62
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  KAKENHI-PUBLICLY-21022030
[Journal Article] Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation2009
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  Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S, Yamamoto M, et.al.
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  Nat Cell Biol 11
  
  Pages: 123-132
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- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] TRAF6 is required for generation of the B-1a B cell compartment as well as T cell-dependent and -independent humoral immune responses.2009
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  Kobayashi T, Kim TS, Jacob A, Walsh MC, Kadono Y, Fuentes-Panana E, Yoshioka T, Yoshimura A, Yamamoto M, et al.
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  PLoS One. 4
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  KAKENHI-PROJECT-21790467
[Journal Article] Two Mechanistically and Temporally Distinct NF-κB Activation Pathways in IL-1 Signaling.2009
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  Yamazaki K, Gohda J, Kanayama A, Miyamoto Y, Sakurai H, Yamamoto M, et al.
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  Sci Signal. 2
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  KAKENHI-PROJECT-21790467
[Journal Article] Involvement of linear polyubiquitylation of NEMO in NF-κB activation.2009
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  Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S, Yamamoto M, et al
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  Nat Cell Biol. 11
  
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  KAKENHI-PROJECT-21790467
[Journal Article] A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat 3.2009
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  Yamamoto M, et al.
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  J Exp Med. 206
  
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  KAKENHI-PUBLICLY-21022030
[Journal Article] A single polymorphic amino acid on Toxoplasma gondii kinase ROP 16 determines the direct and strain-specific activation of Stat3.2009
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  Yamamoto M, et al.
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  J Exp Med. 206
  
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  KAKENHI-PROJECT-21790467
[Journal Article] NFATcl mediates Toll-like receptor-independent innate immune responses during Trypanosoma cruzi infection.2009
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  Kayama H, Koga R, Atarashi K, Okuyama M, Kimura T, Mak TW, Uematsu S, Akira S, Takayanagi H, Honda K, Yamamoto M, Takeda K.
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  PLoS Pathog. 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790467
[Journal Article] Toll-like receptor 4 signalling through MyD88 is essential to control Salmonella enterica serovar Typhimurium infection, but not for the initiation of bacterial clearance.2009
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  Talbot S, T6temeyer S, Yamamoto M, et al.
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  Immunology 128
  
  Pages: 472-83
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- Data Source
  KAKENHI-PROJECT-21790467
[Journal Article] Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation2009
- Author(s)
  Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S, Yamamoto M, et.al.
- Journal Title
  
  Nat Cell Biol. 11
  
  Pages: 123-132
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- Data Source
  KAKENHI-PROJECT-19041046
[Journal Article] A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.2009
- Author(s)
  Yamamoto M, et al.
- Journal Title
  
  J Exp Med. 206
  
  Pages: 2747-2760
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- Data Source
  KAKENHI-PROJECT-21790467
[Journal Article] Regulation of hematopoiesis by the K63-specificubiquitin-conjugating enzyme Ubc13.2009
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  Wu X, Yamamoto M, et al.
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  Proc Natl Acad Sci USA. 106
  
  Pages: 20836-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790467
[Journal Article] ATP drives lamina propria T(H)17 cell differentiation2008
- Author(s)
  Atarashi K, Nishimura J, Shima T, Umesaki Y, Yamamoto M, et.al.
- Journal Title
  
  Nature. 455
  
  Pages: 808-812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041046
[Journal Article] Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly2008
- Author(s)
  Huen MS, Huang J, Yuan J, Yamamoto M, et.al.
- Journal Title
  
  Mol Cell Biol. 19
  
  Pages: 6104-6112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041046
[Journal Article] Role of nuclear IkappaB proteins in the regulation of host immune responses2008
- Author(s)
  Yamamoto M, Takeda K
- Journal Title
  
  J Infect Chemother 14(4)
  
  Pages: 265-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Lipocalin 2-dependent inhibition of mycobacterial growth in alveolar epithelium2008
- Author(s)
  Saiga H, Nishimura J, Kuwata H, Okuyama M, Matsumoto S, Sato S, Matsumoto M, Akira S, Yoshikai Y, Honda K, Yamamoto M, Takeda K
- Journal Title
  
  J Immunol 181(12)
  
  Pages: 8521-8527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Stat6-independent tissue inflammation occurs selectively on the ocular surface and perioral skin of IkappaBzeta-/- mice2008
- Author(s)
  Ueta M, Hamuro J, Ueda E, Katoh N, Yamamoto M, et.al.
- Journal Title
  
  Invest Ophthalmol Vis Sci 49
  
  Pages: 3387-3394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Class-specific regulation of pro-inflammatory genes by MyD88 pathways and IkappaBzeta2008
- Author(s)
  Kayama H, Ramirez-Carrozzi VR, Yamamoto M, Mizutani T, Kuwata H, Iba H, Matsumoto M, Honda K, Smale ST, Takeda K
- Journal Title
  
  J Biol Chem 283(18)
  
  Pages: 12468-12477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Potent antimycobacterial activity of mouse secretory leukocyte protease inhibitor2008
- Author(s)
  Nishimura J, Saiga H, Sato S, Okuyama M, Kayama H, Kuwata H, Matsumoto S, Nishida T, Sawa Y, Akira S, Yoshikai Y, Yamamoto M, Takeda K
- Journal Title
  
  J Immunol 180(6)
  
  Pages: 4032-4039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Lipocalin 2-dependent inhibition of mycobacterial growth in alveolar epithelium2008
- Author(s)
  Saiga H, Nishimura J, Kuwata H, Okuyama M, Matsumoto S, Sato S, Matsumoto M, Akira S, Yoshikai Y, Honda K, Yamamoto M, Takeda K
- Journal Title
  
  J Immunol. 181
  
  Pages: 8521-8527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041046
[Journal Article] Role of nuclear IkappaB proteins in the regulation of host immune responses2008
- Author(s)
  Yamamoto M, Takeda K.
- Journal Title
  
  J Infect Chemother 14
  
  Pages: 265-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Gene-specific requirement of a nuclear protein, IkappaB-zeta, for promoter association of inflammatory transcription regulators2008
- Author(s)
  Yamazaki S, Matsuo S, Muta T, Yamamoto M, et.al.
- Journal Title
  
  J Biol Chem 283
  
  Pages: 32404-32411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Gene-specific requirement of a nuclear protein, IkappaB-zeta, for promoter association of inflammatory transcription regulators2008
- Author(s)
  Yamazaki S, Matsuo S, Muta T, Yamamoto M, et.al.
- Journal Title
  
  J Biol Chem. 283
  
  Pages: 32404-32411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041046
[Journal Article] ATP drives lamina propria T(H)17 cell differentiation2008
- Author(s)
  Atarashi K, Nishimura J, Shima T, Umesaki Y, Yamamoto M, et.al.
- Journal Title
  
  Nature 455
  
  Pages: 808-812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Stat6-independent tissue inflammation occurs selectively on the ocular surface and perioral skin of IkappaBzeta-/-mice2008
- Author(s)
  Ueta M, Hamuro J, Ueda E, Katoh N, Yamamoto M, et.al.
- Journal Title
  
  Invest Ophthalmol Vis Sci. 46
  
  Pages: 3387-3394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041046
[Journal Article] Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly2008
- Author(s)
  Huen MS, Huang J, Yuan J, Yamamoto M, et.al.
- Journal Title
  
  Mol Cell Biol 19
  
  Pages: 6104-6112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Stat6-independent tissue inflammation occurs selectively on the ocular surface and perioral skin of IkappaBzeta-/- mice2008
- Author(s)
  Ueta M, Hamuro J, Ueda E, Katoh N, Yamamoto M, Takeda K, Akira S, Kinoshita S
- Journal Title
  
  Invest Ophthalmol Vis Sci 49(8)
  
  Pages: 3387-3394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Role of nuclear IkappaB proteins in the regulation of host immune responses2008
- Author(s)
  Yamamoto M, Takeda K.
- Journal Title
  
  J Infect Chemother. 14
  
  Pages: 265-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041046
[Journal Article] ATP drives lamina propria T(H)17 cell differentiation2008
- Author(s)
  Atarashi K, Nishimura J, Shima T, Umesaki Y, Yamamoto M, Onoue M, Yagita H, Ishii N, Evans R, Honda K, Takeda K
- Journal Title
  
  Nature 455(7214)
  
  Pages: 808-812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Lipocalin 2-dependent inhibition of mycobacterial growth in alveolar epithelium2008
- Author(s)
  Saiga H, Nishimura J, Kuwata H, Okuyama M, Matsumoto S, Sato S, Matsumoto M, Akira S, Yoshikai Y, Honda K, Yamamoto M, Takeda K.
- Journal Title
  
  J Immunol 181
  
  Pages: 8521-8527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency2007
- Author(s)
  Yamamoto M, et al
- Journal Title
  
  J Exp Med 204(9)
  
  Pages: 2233-2239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling2007
- Author(s)
  Kawagoe T, Sato S, Jung A, Yamamoto M, et. al.
- Journal Title
  
  J ExP Med. 204
  
  Pages: 1013-1024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] FADD negatively regulates lipopolysaccharide signaling by impairing interleukin-1 receptor-associated kinase 1-MyD88 interaction.2007
- Author(s)
  Zhande R, Dauphinee SM, Thomas JA, Yamamoto M, et. al.
- Journal Title
  
  Mol Cell Biol. 27
  
  Pages: 7394-8404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Journal Article] FADD negatively regulates lipopolysaccharide signaling by impairing interleukin-1 receptor-associated kinase 1-MyD88 interaction.2007
- Author(s)
  Zhande, R・Dauphinee, SM・Thomas, JA・Yamamoto, M, et. al.
- Journal Title
  
  Mol Cell Biol. 27
  
  Pages: 7394-8404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041046
[Journal Article] Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling2007
- Author(s)
  Kawagoe, T・Sato, S・Jung, A・Yamamoto, M, et. al.
- Journal Title
  
  J Exp Med. 204
  
  Pages: 1013-1024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041046
[Journal Article] Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency.2007
- Author(s)
  Yamamoto, M, et. al.
- Journal Title
  
  J Exp Med. 204
  
  Pages: 2233-2239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041046
[Journal Article] Enhanced TLR-mediated NF-Il6 dependent gene expressionby Tribl deficiency.2007
- Author(s)
  Yamamoto, M., et. al.
- Journal Title
  
  J ExP Med. 204
  
  Pages: 233-2239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790357
[Presentation] 病原性寄生虫トキソプラズマの感染免疫学2023
- Author(s)
  山本雅裕
- Organizer
  第23回免疫サマースクール
- Invited
- Data Source
  KAKENHI-ORGANIZER-20H05770
[Presentation] 病原性寄生虫トキソプラズマの感染免疫学2023
- Author(s)
  山本雅裕
- Organizer
  第23回免疫サマースクール
- Invited
- Data Source
  KAKENHI-PROJECT-19H00970
[Presentation] Identification of secreted and non-secreted Toxoplasma virulence factors by in vivo CRISPR screens2023
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 32nd Hot Spring Harbor International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05771
[Presentation] Identification of secreted and non-secreted Toxoplasma virulence factors by in vivo CRISPR screens2023
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 32nd Hot Spring Harbor International Symposium
- Invited
- Data Source
  KAKENHI-ORGANIZER-20H05770
[Presentation] トキソプラズマ原虫に対する宿主セルオートノマス免疫系とその破綻2023
- Author(s)
  山本雅裕
- Organizer
  第75回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-ORGANIZER-20H05770
[Presentation] トキソプラズマ原虫に対する宿主セルオートノマス免疫系とその破綻2023
- Author(s)
  山本雅裕
- Organizer
  第75回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-20H05771
[Presentation] 病原性寄生虫トキソプラズマの感染免疫学2023
- Author(s)
  山本雅裕
- Organizer
  第23回免疫サマースクール
- Invited
- Data Source
  KAKENHI-PLANNED-20H05771
[Presentation] トキソプラズマ原虫に対する宿主セルオートノマス免疫系とその破綻2023
- Author(s)
  山本雅裕
- Organizer
  第75回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H00970
[Presentation] Identification of secreted and non-secreted Toxoplasma virulence factors by in vivo CRISPR screens2023
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 32nd Hot Spring Harbor International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00970
[Presentation] Targeted disruption of IFN-γ-induced IDO1-dependent anti-parasitic response in human cells by Toxoplasma effector TgIST2018
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 3rd Asian Congress of Protistology & 10th Asian Conference of Ciliate Biology & 2nd International Symposium on Biodiversity and Evolution of Protozoa
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0226
[Presentation] Role of cell-intrinsic and innate immunity by interferon-inducible GTPases2018
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 10th Japanese-German Immunology Workshop. Session 3: Uniqueness in the Development and Function of Innate Immunity
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05507
[Presentation] Essential role of ATG proteins in cell-autonomous innate immunity to vacuolar pathogens2018
- Author(s)
  Masahiro Yamamoto
- Organizer
  15th International Conference on Innate Immunity, Aegean Conferences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05507
[Presentation] Interferon-induced activation of cell-autonomous immunity against vacuolar pathogens2016
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 45th Annual meeting of the Japanese Society for Immunology
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15122
[Presentation] Mechanism of IFN-γ-inducible cell-autonomous immunity to intracellular pathogens2016
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 15th Awaji International Forum on Infection and Immunity
- Place of Presentation
  兵庫
- Year and Date
  2016-09-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15122
[Presentation] Interferon-induced activation of cell-autonomous immunity against vacuolar pathogens2016
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 45th Annual meeting of the Japanese Society for Immunology
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04745
[Presentation] Interferon-induced activation of cell-autonomous immunity against vacuolar pathogens2016
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 45th Annual meeting of the Japanese Society for Immunology
- Place of Presentation
  沖縄コンベンションセンター、沖縄県宜野湾市
- Year and Date
  2016-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-WRAPUP-16H01703
[Presentation] Mechanism of IFN-γ-inducible cell-autonomous immunity to intracellular pathogens2016
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 15th Awaji International Forum on Infection and Immunity
- Place of Presentation
  兵庫
- Year and Date
  2016-09-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01377
[Presentation] Mechanism of IFN-γ-inducible cell-autonomous immunity to intracellular pathogens2016
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 15th Awaji International Forum on Infection and Immunity
- Place of Presentation
  兵庫
- Year and Date
  2016-09-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04745
[Presentation] Interferon-induced activation of cell-autonomous immunity against vacuolar pathogens2016
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 45th Annual meeting of the Japanese Society for Immunology
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01377
[Presentation] IFN-γ依存的抗トキソプラズマ応答におけるオートファジー蛋白質の役割2014
- Author(s)
  山本雅裕、大嶋淳、馬知秀、笹井美和、李英愛
- Organizer
  第82回日本寄生虫学会大会
- Place of Presentation
  愛媛大学城北キャンパス、愛媛
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] Role of the mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii2014
- Author(s)
  Ohshima J, Lee Y, Ma JS, Sasai M, Yamamoto M
- Organizer
  第7回寄生虫感染免疫研究会
- Place of Presentation
  ベストウエスタンホテル高山、岐阜
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] Role of the mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii2014
- Author(s)
  Ohshima J, Lee Y, Ma JS, Sasai M, Yamamoto M
- Organizer
  第7回寄生虫感染免疫研究会
- Place of Presentation
  高山、岐阜
- Data Source
  KAKENHI-PUBLICLY-24117512
[Presentation] Role of the mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii2014
- Author(s)
  Ohshima J, Lee Y, Ma JS, Sasai M, Yamamoto M
- Organizer
  第7回寄生虫感染免疫研究会
- Place of Presentation
  高山、岐阜
- Data Source
  KAKENHI-PROJECT-25670201
[Presentation] IFN-γ依存的抗トキソプラズマ応答におけるオートファジー蛋白質の役割2014
- Author(s)
  山本雅裕、大嶋淳、馬知秀、笹井美和、李英愛
- Organizer
  第82回日本寄生虫学会大会
- Place of Presentation
  松山、愛媛
- Data Source
  KAKENHI-PROJECT-25670201
[Presentation] IFN-γ依存的抗トキソプラズマ応答におけるオートファジー蛋白質の役割2014
- Author(s)
  山本雅裕、大嶋淳、馬知秀、笹井美和、李英愛
- Organizer
  第82回日本寄生虫学会大会
- Place of Presentation
  松山、愛媛
- Data Source
  KAKENHI-PUBLICLY-24117512
[Presentation] インターフェロン-γ;誘導性GTPaseによるトキソプラズマ原虫殺傷機構について2014
- Author(s)
  山本雅裕、大嶋淳、Lee Youngae、笹井美和
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会議場、京都
- Year and Date
  2014-10-15
- Invited
- Data Source
  KAKENHI-PUBLICLY-26117713
[Presentation] インターフェロン誘導性遺伝子群GBPの抗トキソプラズマ自然免疫における役割の解明2013
- Author(s)
  山本雅裕、大嶋淳、馬知秀、神山長慶、竹田潔
- Organizer
  第82回日本寄生虫学会大会
- Place of Presentation
  東京
- Year and Date
  2013-03-29
- Invited
- Data Source
  KAKENHI-PUBLICLY-24117512
[Presentation] Selective and Strain-specific NFAT4 activation by a Toxoplasma gondii polymorphic Dense Granule Protein GRA62013
- Author(s)
  Yamamoto M
- Organizer
  International Symposium TCUID2013 Toward Comprehensive Understanding of Immune Dynamism
- Place of Presentation
  吹田、大阪、日本
- Invited
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] A Cluster of IFN-g-inducible p65 GTPases Plays a Critical role in the Host Defense against Toxoplasma gondii2013
- Author(s)
  山本雅裕、馬知秀、大嶋淳、笹井美和
- Organizer
  第6回寄生虫感染免疫研究会
- Place of Presentation
  大分大学・医学部、大分
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] Selective and Strain-specific NFAT4 activation by a Toxoplasma gondii polymorphic Dense Granule Protein GRA62013
- Author(s)
  Yamamoto M
- Organizer
  International Symposium TCUID2013 Toward Comprehensive Understanding of Immune Dynamism
- Place of Presentation
  吹田、大阪
- Invited
- Data Source
  KAKENHI-PROJECT-25670201
[Presentation] Immunological interface between host and a protozoan parasite Toxoplasma gondii2013
- Author(s)
  Yamamoto M
- Organizer
  FORUM GRADUATE SCHOOLS INFECTION & IMMUNITY BIOLOGIE-MEDECINE
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2013-06-28
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] Selective and Strain-specific NFAT4 activation by a Toxoplasma gondii polymorphic Dense Granule Protein GRA62013
- Author(s)
  Yamamoto M
- Organizer
  International Symposium TCUID2013 Toward Comprehensive Understanding of Immune Dynamism
- Place of Presentation
  吹田、大阪
- Invited
- Data Source
  KAKENHI-PUBLICLY-24117512
[Presentation] A Cluster of IFN-g-inducible 65 GTPases Plays a Critical role in the Host Defense against Toxoplasma gondii2013
- Author(s)
  山本雅裕、馬知秀、大嶋淳、笹井美和
- Organizer
  第6回寄生虫感染免疫研究会
- Place of Presentation
  大分
- Year and Date
  2013-03-08
- Data Source
  KAKENHI-PUBLICLY-24117512
[Presentation] A protozoan parasite Toxoplasma gondii manipulates host cell functions by effector molecules2013
- Author(s)
  Yamamoto M
- Organizer
  The XIVth International Congress of Protistology, Symposium 7
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] インターフェロン誘導性遺伝子群GBPの抗トキソプラズマ自然免疫における役割の解明2013
- Author(s)
  山本雅裕、大嶋淳、馬知秀、神山長慶、竹田潔
- Organizer
  第82回日本寄生虫学会大会
- Place of Presentation
  東京医科歯科大学湯島キャンパス、東京
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] Selective and Strain-specific NFAT4 activation by a Toxoplasma gondii polymorphic Dense Granule Protein GRA62013
- Author(s)
  Yamamoto M
- Organizer
  International Symposium TCUID2013 Toward Comprehensive Understanding of Immune Dynamism
- Place of Presentation
  Suita, Osaka, Japan
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] A protozoan parasite Toxoplasma gondii manipulates host cell functions by effector molecules2013
- Author(s)
  Yamamoto M
- Organizer
  The XIVth International Congress of Protistology
- Place of Presentation
  バンクーバー、カナダ
- Invited
- Data Source
  KAKENHI-PROJECT-25670201
[Presentation] インターフェロン誘導性遺伝子群GBPの抗トキソプラズマ自然免疫における役割の解明2013
- Author(s)
  山本雅裕、大嶋淳、馬知秀、神山長慶、竹田潔
- Organizer
  第82回日本寄生虫学会大会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] A protozoan parasite Toxoplasma gondii manipulates host cell functions by effector molecules2013
- Author(s)
  Yamamoto M
- Organizer
  The XIVth International Congress of Protistology,
- Place of Presentation
  バンクーバー、カナダ
- Invited
- Data Source
  KAKENHI-PUBLICLY-24117512
[Presentation] Essential role of interferon-γ-inducible p65 GTPases in host cellular innate immunity against Toxoplasma gondii2012
- Author(s)
  Yamamoto M
- Organizer
  The 11^<th> Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awaji Yumebutai International Conference Center on Awaji Island, Hyogo, Japan
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] Role of GBPs in innate host defense against an intracellular pathogen Toxoplasma gondii2012
- Author(s)
  Yamamoto M
- Organizer
  第41回日本免疫学会総会・学術集会
- Place of Presentation
  神戸国際会議場,神戸、兵庫
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] Critical function of a Cluster of IFN-γ-indudible p65 GTPases in Host Defense Against Toxoplasma gondii2012
- Author(s)
  Yamamoto M, Okuyama M, Ma JS, Kamiyama N, Ohshima J, Soldati-Favre D, Takeda J, Takeda K
- Organizer
  WHIP 2012 16^<th> Annual Woods Hole ImmunoParasitology Conference
- Place of Presentation
  Marine Biological Laboratory, Woods Hole, MA, USA
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] Role of GBPs in innate host defense against an intracellular pathogen Toxoplasma gondii2012
- Author(s)
  Yamamoto M
- Organizer
  第41回日本免疫学会総会・学術集会
- Place of Presentation
  兵庫
- Invited
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] A Toxoplasma virulence factor ROP18 disrupts a host innate and adaptive immune linkage2011
- Author(s)
  山本雅裕
- Organizer
  The Second CSI/JSI/KAI Joint Symposium on Immunology "Regulation of Immune Responses in Health and Diseases
- Place of Presentation
  Osaka University, Osaka, Japan(招待講演)
- Year and Date
  2011-12-05
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] A Toxoplasma virulence factor ROP18 disrupts a host innate and adaptive immune linkage2011
- Author(s)
  Masahir o Yamamoto
- Organizer
  The Second CSI/JSI/KAI Joint Symposium on Immunology"Regulation of Immune Responses in Health and Diseases
- Place of Presentation
  Osaka University, Osaka, Japan
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] ATF6b is a Host Cellular Target of the Toxoplasma Virulence factor ROP182011
- Author(s)
  山本雅裕
- Organizer
  WHIP 2011 15th Annual Woods Hole ImmunoParasitology Conference
- Place of Presentation
  Marine Biological Laboratory, Woods Hole, MA, USA
- Year and Date
  2011-04-18
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] Targeted disruption of an ATF6β-dependent host type I immunity by a Toxoplasma virulence factor ROP182011
- Author(s)
  Masahir o Yamamoto, Naganori Kamiyama, Ji Su Ma, Christina Mueller, Dominique Soldati-Favre, Kiyoshi Takeda
- Organizer
  IUMS2011 XIII International Congerss of Bacteriology and Applied Microbiology
- Place of Presentation
  Sapporo Convention Center, Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] Targeted disruption of an ATF6β-dependent host type I immunity by a Toxoplasma virulence factor ROP182011
- Author(s)
  山本雅裕
- Organizer
  IUMS2011 XIII International Congerss of Bacteriology and Applied Microbiology
- Place of Presentation
  Sapporo Convention Center, Sapporo, Japan(招待講演)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] A mechanism of innate immune evasion by a protozoan parasite2011
- Author(s)
  Masahir o Yamamoto
- Organizer
  SRC Mini Symposium II"Immune Regulation & Immune Evasion"
- Place of Presentation
  UNIST, Ulsan, Koera
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] A mechanism of innate immune evasion by a protozoan parasite2011
- Author(s)
  山本雅裕
- Organizer
  SRC Mini Synposium II "Immune Regulation & Immune Evasion"
- Place of Presentation
  UNIST, Ulsan, Koera(招待講演)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] ATF6βis a Host Cellular Target of the Toxoplasma Virulence factor ROP182011
- Author(s)
  Yamamoto M, Ma JS, Mulleler C, Kamiyama N, Soldati-Favre D, Takeda K
- Organizer
  WHIP 2011 15^<th> Annual Woods Hole ImmunoParasitology Conference
- Place of Presentation
  Marine Biological Laboratory, Woods Hole, MA, USA
- Data Source
  KAKENHI-PROJECT-23689029
[Presentation] I型トキソプラズマ原虫の病原性におけるROP18の役割2010
- Author(s)
  山本雅裕
- Organizer
  第9回分子寄生虫・マラリア研究フォーラム
- Place of Presentation
  長崎大学坂本キャンパス良順会館ボードインホール
- Data Source
  KAKENHI-PUBLICLY-21022030
[Presentation] トキソプラズマ原虫リン酸化酵素ROP16による宿主自然免疫系の制御について2010
- Author(s)
  山本雅裕
- Organizer
  第62回細胞生物学会、シンポジウム4(S4)感染症と細胞生物学のインターフェース
- Place of Presentation
  グランキューブ大阪(招待講演)
- Data Source
  KAKENHI-PROJECT-21790467
[Presentation] I型トキソプラズマ原虫の病原性におけるROP18の役割2010
- Author(s)
  山本雅裕
- Organizer
  第9回分子寄生虫・マラリア研究フォーラム
- Place of Presentation
  長崎大学坂本キャンパス良順会館ボードインホール
- Data Source
  KAKENHI-PROJECT-21790467
[Presentation] Essential role of ROP16 in the strain-specific and direct activation of Stat3 and Stat62010
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 4^<th> International Symposium of WPI-IFReC
- Place of Presentation
  Icho-Kaikan, Suita Campus, Osaka University(招待講演)
- Data Source
  KAKENHI-PUBLICLY-21022030
[Presentation] Essential role of ROP16 in the strain-specific and direct activation of Stat3 and Stat62010
- Author(s)
  Masahiro Yamamoto
- Organizer
  The 4^<th> International Symposium of WPI-IFReC
- Place of Presentation
  Icho-Kaikan, Suita Campus, Osaka University(招待講演)
- Data Source
  KAKENHI-PROJECT-21790467
[Presentation] トキソプラズマ原虫リン酸化酵素ROP16による宿主自然免疫系の制御について2010
- Author(s)
  山本雅裕
- Organizer
  第62回細胞生物学会、シンポジウム4(S4)感染症と細胞生物学のインターフェース
- Place of Presentation
  グランキューブ大阪(招待講演)
- Data Source
  KAKENHI-PUBLICLY-21022030
[Presentation] Essential role of Toxoplasma gondii ROP16 in host Stat3 activation2009
- Author(s)
  Yamamoto M, Soldati-Favre D, Takeda K.
- Organizer
  The 9^<th> Awaji International Forum on lnfection and Immunity(Awaji Yumebutai Intemational Conference Center on Awaji Island
- Place of Presentation
  Hyogo, Japan
- Data Source
  KAKENHI-PROJECT-21790467
[Presentation] トキソプラズマ原虫のリン酸化酵素であるROP16はStat3を直接活性化する2009
- Author(s)
  山本雅裕、Dominiquie Soldati-Favre, 竹田潔
- Organizer
  第8回分子寄生虫・マラリア研究フォーラム
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-21790467
[Presentation] トキソプラズマ原虫のキナーゼであるROP16上の多型的な1つのアミノ酸置換が株特異的かつ直接的なStat3のリン酸化を決定する2009
- Author(s)
  Yamamoto M, Soldati-Favre D, Takeda K.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-21790467
[Presentation] A single polymorphic amino substitution on Toxoplasma gondii kinase ROP16 detemines the direct and strain-specific activation of Stat3.2009
- Author(s)
  Yamamoto M,.
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PUBLICLY-21022030
[Presentation] トキソプラズマ原虫のキナーゼであるROP16上の多型的な1つのアミノ酸置換が株特異的かつ直接的なStat3のリン酸化を決定する2009
- Author(s)
  Yamamoto M, Soldati-FavreD, Takeda K.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PUBLICLY-21022030
[Presentation] 第二回原虫感染免疫研究会2009
- Author(s)
  山本雅裕
- Place of Presentation
  佐賀、日本
- Data Source
  KAKENHI-PROJECT-19790357
[Presentation] 第二回原虫感染免疫研究会2009
- Author(s)
  山本雅裕
- Place of Presentation
  佐賀、日本
- Data Source
  KAKENHI-PROJECT-19041046
[Presentation] A single polymorphic amino substitution on Toxoplasma gondii kinase ROP16 detemines the direct and strain-specific activation of Stat3.2009
- Author(s)
  Yamamoto M.
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-21790467
[Presentation] Differential Regulation of Primary and Secondary Response Genes by MyD88 Pathways and IκBζ2008
- Author(s)
  Kayama H, Ramirez-Carrozzi V, Yamamoto M, Smale S, Takeda K
- Organizer
  Keystone Symposia, Innate Immunity: Signaling Mechanisms
- Place of Presentation
  Keystone Resort, Keystone, Colorado
- Data Source
  KAKENHI-PROJECT-19790357
[Presentation] Trib1 is a negative regulator of NF-IL6 in TLR signalling2008
- Author(s)
  Masahiro, Yamamoto
- Organizer
  Keystone Symposia, Innate Immunity
- Place of Presentation
  Keystone 米国
- Year and Date
  2008-02-27
- Data Source
  KAKENHI-PROJECT-19041046
[Presentation] Trib1 is a negative regulator of NF-IL6 in TLR signaling2008
- Author(s)
  Yamamoto M, Uematsu S, Takeda K, Kawai T, Akira S
- Organizer
  Keystone Symposia, Innate Immunity: Signaling Mechanisms
- Place of Presentation
  Keystone Resort, Keystone, Colorado
- Data Source
  KAKENHI-PROJECT-19790357
[Presentation] Tribl is a negative regulator of NF-IL6 in TLR signalling2008
- Author(s)
  Masahiro Yamamoto
- Organizer
  Keystone Symposia, Innate Immunity
- Place of Presentation
  Keystone 米国
- Year and Date
  2008-02-27
- Data Source
  KAKENHI-PROJECT-19790357
[Presentation] Critical role of mouse secretory leukocyte protease inhibitor in mycobacterial infection2007
- Author(s)
  Nishimura J, Saiga H, Matsumoto S, Kuwata H, Yoshikai Y, Yamamoto M, Takeda K
- Organizer
  第37 回日本免疫学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪
- Data Source
  KAKENHI-PROJECT-19790357
[Presentation] Toll-like receptor (TLR)アダプター分子・TRIF によるTrypanosomacruzi に対する感染防御機構2007
- Author(s)
  山本雅裕
- Organizer
  第15 回分子寄生虫学ワークショップ
- Place of Presentation
  草津セミナーハウス
- Data Source
  KAKENHI-PROJECT-19790357
[Presentation] Stat6 independent tissue inflammation of IκBζ KO mice selective in ocular surface and perioral skin2007
- Author(s)
  Ueta M, Hamuro J, Ueda E, Katoh N, Yamamoto M, Akira S, Kinoshita S
- Organizer
  第37 回日本免疫学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪
- Data Source
  KAKENHI-PROJECT-19790357
[Presentation] C/EBPb isoform, 34 kDa LAP is responsible for NF-IL6-mediated gene induction in activated macrophages but not essential for intracellular bacteria killing2007
- Author(s)
  Uematsu S, Kaisho T, Tanaka T, Matsumoto M, Yamamoto M, Akira S
- Organizer
  第37 回日本免疫学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪
- Data Source
  KAKENHI-PROJECT-19790357
[Presentation] LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses2007
- Author(s)
  Kato H, Sato S, Yamamoto M, Uematsu S, Matsushita K, Jung A, Ishii K, Kawai T, Takeuchi O, Akira S
- Organizer
  第37 回日本免疫学会総会・学術集会
- Place of Presentation
  グランドプリンスホテル新高輪
- Data Source
  KAKENHI-PROJECT-19790357
[Presentation] Immunological interface between host and a protozoan parasite Toxoplasma gondii
- Author(s)
  Yamamoto M
- Organizer
  FORUM GRADUATE SCHOOLS INFECTION & IMMUNITY BIOLOGIE-MEDECINE
- Place of Presentation
  ジュネーブ、スイス
- Invited
- Data Source
  KAKENHI-PROJECT-25670201
[Presentation] NFAT4 activation by the Toxoplasma gondii polymorphic effector protein GRA6 maximizes the parasite virulence in a strain-specific manner
- Author(s)
  Yamamoto M
- Organizer
  The 13th Awaji International Forum on Infection and Immunity
- Place of Presentation
  Nara Prefectural New Public Hall, Nara
- Year and Date
  2014-09-23 – 2014-09-26
- Invited
- Data Source
  KAKENHI-PUBLICLY-26117713

1. TAKASHIMA Yasuhiro (20333552)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 笹井美和 (30631551)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
3. Hoshina Tokio (60648830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KANUKA Hirotaka (50342770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Aonuma Hiroka (60451457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAIKI Erisha (70738971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. FUKUMOTO Shinya (50376422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 野崎智義 (60198588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 守屋繁春 (00321828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 松崎素道 (00511396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 石田健一郎 (30282198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 神川龍馬 (40627634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 小保方潤一 (50185667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 稲垣祐司 (50387958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 木原久美子 (50622916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 馬知秀 (90755266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. 橋口隆生 (50632098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 新崎恒平 (70609990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 神山長慶 (50756830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 西田欣広 (10336274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 小林隆志 (30380520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 正谷達謄 (70614072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 宮脇慎吾 (70756759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 中川敬介 (90853250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. HORII Toshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. SAITOH Tatsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 李英愛

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 竹居孝二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 山田浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 東岸任弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 伴戸寛徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
32. 岩永史朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMAMOTO Masahiro 山本 雅裕

Research Projects

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新規先天性トキソプラズマ症モデルマウスによるその予防法の開発

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Development of novel normal and disease-specific macrophage depletion method using VeDTR mouse systemPrincipal Investigator

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致死性病原体の潜伏を可能にする野生動物の分子免疫機構

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Establishment of PLAMP as a new concept to determine self and nonself for obligatory intracellular pathogensArea Organizer

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Management of PLAMP researchPrincipal Investigator

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Elucidation of protozoan PLAMP generation mechanism recognized by host cell-autonomous immunityPrincipal Investigator

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The molecular mechanisms of Toxoplasma gondii and Neospora caninum reactivation from latency.

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Physiological mechanisms to maintain self and nonself on intracellular membranes, and its pathological failurePrincipal Investigator

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Elucidation of interferon-dependent host defense system against legal infectious disease-causing microbes for domestic animalsPrincipal Investigator

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Pathogenic and genetic analysis of Toxoplasma by Japan, China and South KoreaPrincipal Investigator

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Elucidation of novel mechanism to discriminate intracellular membranes using Toxoplasma gondiiPrincipal Investigator

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細菌含有膜破壊によるパイロトーシス誘導・制御メカニズムの解明Principal Investigator

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Development of novel serodiagnostic method for the detection of active toxoplasmosis

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YAMAMOTO Masahiro 山本雅裕