SUZUKI Hitoshi 鈴木仁

Researcher Number	00447690
Affiliation (based on the past Project Information) *help	2016: 北陸先端科学技術大学院大学, 先端科学技術研究科, 助教 2016: 北陸先端科学技術大学院大学, 先端科学技術研究科, 特任助教 2014 – 2016: 北陸先端科学技術大学院大学, マテリアルサイエンス研究科, 助教 2014 – 2015: 北陸先端科学技術大学院大学, マテリアルサイエンス研究科, 特任助教 2010 – 2013: 北陸先端科学技術大学院大学, ナノマテリアルテクノロジーセンター, 助教
Review Section/Research Field	Principal Investigator Genome biology / Tumor biology / Medical genome science Except Principal Investigator Human genetics / Medical genome science
Keywords	Principal Investigator 細胞周期 / ヌクレオフォスミン / 選択的スプライシング / エキソンスキップ治療 / 疾患関連遺伝子 / スプライシング / RNA Except Principal Investigator RNA editing / ガイドRNA / 活性部位 … More / デアミナーゼ / 遺伝子修復 / guide RNA / 活性ドメイン / MS2 / Deaminase / 恒常発現細胞株 / RNA Editing / 恒常的発現細胞株 / 恒常的発言細胞株 / 恒常的発現細胞 / RFLP / 遺伝コード修復 / 蛍光タンパク質 / 脱アミノ化 / 点変異 / 疾患治療 Less

転写非共役的スプライシングに依存するcircRNAの生成Principal Investigator
- Principal Investigator
  
  鈴木仁
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genome biology
- Research Institution
  Japan Advanced Institute of Science and Technology
Development of genetic code restoration by using artificial RNA editing
- Principal Investigator
  
  TSUKAHARA Toshifumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Human genetics
- Research Institution
  Japan Advanced Institute of Science and Technology
Establishment of chemical RNA editing method for genetic code resoration therapy
- Principal Investigator
  
  Tsukahara Toshifumi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical genome science
- Research Institution
  Japan Advanced Institute of Science and Technology
Investigation into novel splicing targets of NucleophosminPrincipal Investigator
- Principal Investigator
  
  SUZUKI Hitoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Japan Advanced Institute of Science and Technology
Evidences of a novel splicing mechanism in DMD genePrincipal Investigator
- Principal Investigator
  
  SUZUKI Hitoshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical genome science
- Research Institution
  Japan Advanced Institute of Science and Technology

All 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

[Book] New Development in Alternative Splicing Research; Comprehensive analyses of alternative exons in neuronally differentiated P19 cells.2013
- Author(s)
  Suzuki H. and Tsukahara T.
- Total Pages
  20
- Publisher
  NOVA Science Publishers
- Data Source
  KAKENHI-PROJECT-24700974
[Book] New Developments on Alternative Splicing Research2013
- Author(s)
  Hitoshi Suzuki and Toshifumi Tsukahara
- Total Pages
  181
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-25290072
[Journal Article] Neuron-specific splicing2017
- Author(s)
  Nor Hakimah Ab Hakim, Burhanuddin Yeop Majlis, Hitoshi Suzuki, Toshifumi Tsukahara,
- Journal Title
  
  BioScience Trends
  
  Volume: 11 Issue: 1 Pages: 16-22
- DOI
  10.5582/bst.2016.01169
- NAID
  130005466226
- ISSN
  1881-7815, 1881-7823
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290072
[Journal Article] Expression Analysis of Fox-2 Alternative Isoforms during Neuronal Differentiation2016
- Author(s)
  Nor Hakimah Ab Hakim, Burhanuddin Yeop Majlis, Hitoshi Suzuki and Toshifumi Tsukahara
- Journal Title
  
  Int’l Journal of Advances in Chemical Engg., & Biological Sciences
  
  Volume: 3 Issue: 1 Pages: 102-104
- DOI
  10.15242/ijacebs.iae0516407
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290072
[Journal Article] Chemical RNA Editing for Genetic Restoration: The Relationship between the Structure and Deamination Efficiency of Carboxyvinyldeoxyuridine Oligodeoxynucleotides2016
- Author(s)
  Vu Thi Luyen, Nguyen Thi Kim Thanh, Md Thoufic Anam Azad, Hitoshi Suzuki, and Toshifumi Tsukahara
- Journal Title
  
  Chemical Biology & Drug Design
  
  Volume: 87 Issue: 4 Pages: 583-593
- DOI
  10.1111/cbdd.12693
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670167, KAKENHI-PROJECT-25290072
[Journal Article] Endogenous Multiple Exon Skipping and Back-Splicing at the DMD Mutation Hotspot2016
- Author(s)
  Hitoshi Suzuki, Yoshitsugu Aoki, Toshiki Kameyama, Takashi Saito, Satoru Masuda, Jun Tanihata, Tetsuya Nagata, Akila Mayeda, Shin’ichi Takeda, Toshifumi Tsukahara
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 17 Issue: 10 Pages: 1722-1722
- DOI
  10.3390/ijms17101722
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25290072, KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-16K14659
[Journal Article] Changing Blue Fluorescent Protein to Green Fluorescent Protein Using Chemical RNA Editing as a Novel Strategy in Genetic Restoration2015
- Author(s)
  Luyen T. Vu, Thanh T. K. Nguyen, Shafiul Alam, Takashi Sakamoto, Kenzo Fujimoto, Hitoshi Suzuki and Toshifumi Tsukahara
- Journal Title
  
  Chemical Biology & Drug Design
  
  Volume: 86 Issue: 5 Pages: 1242-1252
- DOI
  10.1111/cbdd.12592
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670167, KAKENHI-PROJECT-25290072
[Journal Article] Computational extraction of a neural molecular network through alternative splicing2014
- Author(s)
  Alam S, Phan HT, Okazaki M, Takagi M, Kawahara K, Tsukahara T, Suzuki H
- Journal Title
  
  BMC Res. Notes
  
  Volume: 7 Issue: 1 Pages: 934-934
- DOI
  10.1186/1756-0500-7-934
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24700974, KAKENHI-PROJECT-25290072, KAKENHI-PROJECT-26289311, KAKENHI-PROJECT-26670167
[Journal Article] A View of Pre-mRNA Splicing from RNase R Resistant RNAs2014
- Author(s)
  Suzuki H, Tsukahara T
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 15 Issue: 6 Pages: 9331-9342
- DOI
  10.3390/ijms15069331
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24700974, KAKENHI-PROJECT-25290072, KAKENHI-PROJECT-26670167
[Journal Article] Alternative splicing regulation of APP exon 7 by RBFox proteins2014
- Author(s)
  Alam S, Suzuki H, Tsukahara T
- Journal Title
  
  Neurochem. Int.
  
  Volume: 78 Pages: 7-17
- DOI
  10.1016/j.neuint.2014.08.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24700974, KAKENHI-PROJECT-25290072, KAKENHI-PROJECT-26670167
[Journal Article] Nested introns in an intron : Evidence of multi-step splicing in a large intron of the human dystrophin pre-mRNA.2013
- Author(s)
  Suzuki, H., Kameyama, T., Ohe, K. Tsukahara, T., Mayeda, A.
- Journal Title
  
  FEBS Letters
  
  Volume: 587 Issue: 6 Pages: 555-561
- DOI
  10.1016/j.febslet.2013.01.057
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23112722, KAKENHI-PROJECT-24591920, KAKENHI-PROJECT-24700974, KAKENHI-PROJECT-25290072, KAKENHI-PROJECT-25640081
[Journal Article] Alternative splicing produces structural and functional changes in CUGBP22012
- Author(s)
  Suzuki, H., Takeuchi, M., Sugiyama, A., Alam, A. H. M. K., Vu, T. L., Sekiyama, Y., Dam, C. H., Ohki, S., and Tsukahara, T.
- Journal Title
  
  BMC Biochem
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22710192
[Journal Article] Re-splicing of mature mRNA in cancer cells promotes activation of distant weak alternative splice sites2012
- Author(s)
  Kameyama, T., Suzuki, H., and Mayeda, A.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22710192
[Journal Article] Functional gene expression analysis of tissue-specific is forms of Mef2c2012
- Author(s)
  Sekiyama, Y., Suzuki, H., and Tsukahara, T.
- Journal Title
  
  Cell. Mol
  
  Volume: 32 Pages: 129-139
- Data Source
  KAKENHI-PROJECT-22710192
[Journal Article] Alternative Splicing Produces Structural and Functional Changes in CUGBP22012
- Author(s)
  鈴木仁
- Journal Title
  
  BMC Biochemistry
  
  Volume: 13 Issue: 1 Pages: 6-6
- DOI
  10.1186/1471-2091-13-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710192
[Journal Article] Comprehensive Analysis of Alternative Splicings and Functionality in Neuronal Differentiation of P19 cells2011
- Author(s)
  Suzuki, H., Osaki, K., Sano, K., Alam, A. H. M. K., Nakamura, Y., Ishigaki, Y., Kawahara, K., and Tsukahara, T.
- Journal Title
  
  PLoS One
  
  Volume: 6
- Data Source
  KAKENHI-PROJECT-22710192
[Journal Article] Comprehensive Analysis of Alternative Splicings and Functionality in Neuronal Differentiation of P19 cells2011
- Author(s)
  鈴木仁
- Journal Title
  
  PLoS One
  
  Volume: 6 Pages: 16880-16880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710192
[Journal Article] Retinoic acid treatment and cell aggregation independently regulate alternative splicing in P19 cells during neural differentiation2010
- Author(s)
  Alam, A. H. M. K., Suzuki, H., and Tsukahara, T.
- Journal Title
  
  Cell. Biol. Int
  
  Volume: 34 Pages: 631-643
- Data Source
  KAKENHI-PROJECT-22710192
[Presentation] Site-directed RNA editing approach by MS2 and adenosine deaminase acting on RNA (ADAR)2016
- Author(s)
  Md Thoufic Anam Azad, Hitoshi Suzuki, Toshifumi Tsukahara
- Organizer
  日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25290072
[Presentation] Study of adenosine deaminase acting on RNA (ADAR) isoforms towards genetic code restoration2016
- Author(s)
  Md Thoufic Anam Azad, Hitoshi Suzuki, Toshifumi Tsukahara
- Organizer
  アメリカ細胞生物学会年会
- Place of Presentation
  サンフランシスコ（アメリカ合衆国）
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290072
[Presentation] Circular RNA and multiexon-skipping in the DMD gene hotspot2014
- Author(s)
  Suzuki H
- Organizer
  RIKEN Symposium/15 th Tokyo RNA Club, Noncoding RNA Regulation
- Place of Presentation
  理化学研究所和光キャンパス　鈴木梅太郎ホール　（埼玉県　和光市）
- Year and Date
  2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-24700974
[Presentation] DMD遺伝子のホットスポットのスキップ産物とcircRNA2013
- Author(s)
  鈴木　仁、亀山俊樹、前田　明、塚原俊文
- Organizer
  第15回日本RNA学会年会
- Place of Presentation
  愛媛県松山市
- Data Source
  KAKENHI-PROJECT-24700974
[Presentation] P19細胞の神経分化における選択的スプライシングの網羅的解析と経路網探索2010
- Author(s)
  鈴木仁
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  東京
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-22710192
[Presentation] P19細胞の神経分化における選択的スプライシングの網羅的解析と経路網探索2010
- Author(s)
  鈴木仁
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  一橋記念講堂(東京)
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-22710192
[Presentation] Circular RNAとスプライシング
- Author(s)
  鈴木　仁
- Organizer
  第一回北陸エピジェネティクス研究会
- Place of Presentation
  金沢大学付属医学部図書館　十全記念スタジオ　（石川県　金沢市）
- Year and Date
  2014-11-18 – 2014-11-19
- Invited
- Data Source
  KAKENHI-PROJECT-24700974
[Presentation] RBFoxによるAPP遺伝子exon7のスプライシング制御
- Author(s)
  アラム　シャフュール、鈴木　仁、塚原俊文
- Organizer
  第16回日本RNA学会年会
- Place of Presentation
  ウインクあいち（愛知県　名古屋市）
- Year and Date
  2014-07-22 – 2014-07-24
- Data Source
  KAKENHI-PROJECT-24700974
[Presentation] 環状型転写産物の包括的理解に向けたDMD遺伝子ホットスポットの解析
- Author(s)
  鈴木　仁、亀山俊樹、前田　明、塚原俊文
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　（神奈川県　横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24700974

1. Tsukahara Toshifumi (60207339)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
2. Takada Shin'ichi (90171644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. TATENO MASARU (40291926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 藤本健造 (90293894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MAYEDA Akila

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

SUZUKI Hitoshi 鈴木 仁

Research Projects

Research Products

Co-Researchers

転写非共役的スプライシングに依存するcircRNAの生成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of genetic code restoration by using artificial RNA editing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of chemical RNA editing method for genetic code resoration therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation into novel splicing targets of NucleophosminPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evidences of a novel splicing mechanism in DMD genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] New Development in Alternative Splicing Research; Comprehensive analyses of alternative exons in neuronally differentiated P19 cells.2013

Author(s)

Total Pages

Publisher

Data Source

[Book] New Developments on Alternative Splicing Research2013

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Neuron-specific splicing2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Expression Analysis of Fox-2 Alternative Isoforms during Neuronal Differentiation2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemical RNA Editing for Genetic Restoration: The Relationship between the Structure and Deamination Efficiency of Carboxyvinyldeoxyuridine Oligodeoxynucleotides2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endogenous Multiple Exon Skipping and Back-Splicing at the DMD Mutation Hotspot2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Changing Blue Fluorescent Protein to Green Fluorescent Protein Using Chemical RNA Editing as a Novel Strategy in Genetic Restoration2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Computational extraction of a neural molecular network through alternative splicing2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A View of Pre-mRNA Splicing from RNase R Resistant RNAs2014

Author(s)

Journal Title

SUZUKI Hitoshi 鈴木仁