Isohashi Fumiaki 礒橋文明

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ISOHASHI Fumiaki 礒橋文明

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Researcher Number	00448036
Other IDs
Affiliation (Current)	2025: 奈良県立医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2024: 奈良県立医科大学, 医学部, 教授 2022: 大阪大学, 大学院医学系研究科, 准教授 2020 – 2021: 大阪大学, 医学系研究科, 准教授 2018: 大阪大学, 医学系研究科, 特任准教授(常勤) 2017 – 2018: 大阪大学, 医学系研究科, 准教授 … More 2016: 大阪大学, 医学系研究科, 特任准教授(常勤) 2015: 大阪大学, 医学(系)研究科(研究院), 特任准教授(常勤) 2015: 大阪大学, 医学系研究科, 特任准教授 2014 – 2015: 大阪大学, 医学(系)研究科(研究院), 准教授 2013: 大阪大学, 医学(系)研究科(研究院), 特任准教授(常勤) 2009 – 2010: Osaka University, 医学系研究科, 助教 Less
Review Section/Research Field	Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related Except Principal Investigator Radiation science
Keywords	Principal Investigator 放射線治療 / 機能画像 / 放射線治療計画 / Human papillomavirus / リキッドバイオプシー / HPV / 子宮頸癌 / 放射線腫瘍学 / 放射線科学 / ポリアミン代謝 … More / 癌幹細胞 / 骨髄抑制 / 急性期有害事象 / 放射線治療学 / 小線源治療 / 経時的解析 / 酸素分圧 / 前立腺癌 / 低酸素 … More Except Principal Investigator 放射線増感 / 創薬 / 癌幹細胞 / 放射線治療 / 化合物スクリニーニング / 放射線増感剤 Less

Establishment of a functionally informed radiotherapy planning evaluation methodPrincipal Investigator
- Principal Investigator
  
  礒橋文明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Nara Medical University
Monitoring of residual and recurrence of cervical cancer after radiotherapy using blood liquid biopsy.Principal Investigator
- Principal Investigator
  
  Isohashi Fumiaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Osaka University
The relationships between radioresistance and polyamine metabolism in cervical cancer stem cellPrincipal Investigator
- Principal Investigator
  
  Fumiaki Isohashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
Identification of radiosensitizers targeting cancer stem cells in cervical cancer by using high throughput screening
- Principal Investigator
  
  Tamari Keisuke
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
Effectiveness of bone marrow sparing IMRT using FLT-PETPrincipal Investigator
- Principal Investigator
  
  ISOHASHI Fumiaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University
Sequential analysis of the acute hypoxia with the irradiation for prostate cancerPrincipal Investigator
- Principal Investigator
  
  ISOHASHI Fumiaki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Osaka University

All 2018 2016 2015 2014 2010 2009 Other

All Journal Article Presentation

[Journal Article] Polyamine flux suppresses histone lysine demethylases and enhances ID1 expression in cancer stem cells2018
- Author(s)
  Tamari K, KonnoM , Asai A, Koseki J, Hayashi K, Kawamoto K, Murai N, Matsufuji S, Isohashi F, Satoh T, Gotoh N, Tanaka S, Doki Y, Mori M, Ogawa K, Ishii H.
- Journal Title
  
  Cell Death Discovery
  
  Volume: 4 Issue: 104 Pages: 104-104
- DOI
  10.1038/s41420-018-0117-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-18K16355, KAKENHI-PROJECT-18K16356, KAKENHI-PROJECT-18KK0251, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-16K10393, KAKENHI-PROJECT-17K19587, KAKENHI-PROJECT-17K19698, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06279
[Journal Article] Dose-volume analysis of predictors for chronic gastrointestinal complications in patients with cervical cancer treated with postoperative concurrent chemotherapy and whole-pelvic radiation therapy2016
- Author(s)
  Isohashi F, Mabuchi S, Akino Y, Yoshioka Y, Seo Y, Suzuki O, Tamari K, Yoshino K, Sawada K, Ueda Y, Kobayashi E, Sumida I, Mizuno Y, Okubo H, Kimura T, Ogawa K.
- Journal Title
  
  J Radiat Res
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25861097
[Journal Article] Intensity-modulated radiation therapy versus three-dimensional conformal radiation therapy with concurrent nedaplatin-based chemotherapy after radical hysterectomy for uterine cervical cancer: comparison of outcomes, complications, and dose-volume histogram parameters.2015
- Author(s)
  Isohashi F, Mabuchi S, Yoshioka Y, Seo Y, Suzuki O, Tamari K, Yamashita M, Unno H, Kinosa Y, Kozasa K, Sumida I, Otani Y, Kimura T, Ogawa K.
- Journal Title
  
  Radiat Oncol
  
  Volume: 10 Issue: 1 Pages: 180-180
- DOI
  10.1186/s13014-015-0486-5
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25861097
[Journal Article] What is the Optimum Minimum Segment Size Used in Step and Shoot IMRT for Prostate Cancer?2010
- Author(s)
  高橋豊、礒橋文明
- Journal Title
  
  J Radiat Res (Tokyo)
  
  Volume: 51 Pages: 543-552
- NAID
  10026644341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791193
[Journal Article] Concurrent weekly nedaplatin, external beam radiotherapy and high-dose-rate barchytherapy in patients with FIGO stage IIIb cervical cancer : A comparison with a cohort treated by radiotherapy alone2010
- Author(s)
  馬淵誠士、礒橋文明
- Journal Title
  
  Gynecol Obstet Invest
  
  Volume: 69 Pages: 224-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791193
[Journal Article] Prognostic factors for survival in patients with recurrent cervical cancer previously treated with radiotherapy2010
- Author(s)
  馬淵誠士、礒橋文明
- Journal Title
  
  Int J Gynecol Cancer
  
  Volume: 20 Pages: 834-840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791193
[Journal Article] Rectal dose and source strength of the high-dose-rate iridium-192 both affect late rectal bleeding after intracavitary radiation therapy for uterine cervical carcinoma2010
- Author(s)
  礒橋文明
- Journal Title
  
  Int J Radiat Oncol Biol Phys
  
  Volume: 77 Pages: 758-764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791193
[Journal Article] High-dose-rate interstitial brachytherapy for previously untreated cervical carcinoma2009
- Author(s)
  礒橋文明
- Journal Title
  
  Brachytherapy 8
  
  Pages: 234-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791193
[Journal Article] Correlation between dosimetric parameters and late rectal and urinary toxicities in patients treated with high-dose-rate brachytherapy used as monotherapy for prostate cancer.2009
- Author(s)
  Konishi K, Yoshioka Y, Isohashi F, Sumida I, Kawaguchi Y, Kotsuma T. Adachi K, Morimoto M, Fukuda S, Inoue T.
- Journal Title
  
  Int J Radiat Oncol Biol Phys 75(4)
  
  Pages: 1003-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791193
[Journal Article] Monotherapeutic high-dose-rate brachytherapy for prostate cancer : five-year results of an extreme hypofractionation regimen with 54 Gy in nine fractions.
- Author(s)
  Yoshioka Y, Konishi K, Sumida I, Takahashi Y, Isohashi F, Ogata T, Koizumi M, Yamazaki H, Nonomura N, Okuyama A, Inoue T.
- Journal Title
  
  Int J Radiat Oncol Biol Phys in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791193
[Presentation] Identification of novel radiosensitizers targeting hypoxic cancer cells by high throughput screening2016
- Author(s)
  Tamari K, Seo Y, Takahashi Y, Suzuki O, Isohashi F, Yoshioka Y, and Ogawa K.
- Organizer
  Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  Hyatt Regency Maui Maui, Hawaii
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670559
[Presentation] A novel method to identify radiosensitizers targeting hypoxic cancer cells by high throughput screening2016
- Author(s)
  Tamari K, Seo Y, Takahashi Y, Suzuki O, Isohashi F, Yoshioka Y, and Ogawa K.
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  Ernest N. Morial Convention Center New Orleans, Louisiana
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670559
[Presentation] Intensity-modulated radiation therapy versus three-dimensional conformal radiation therapy with concurrent nedaplatin-based chemotherapy after radical hysterectomy for uterine cervical cancer: comparison of outcomes, complications, and dose-volume histogram parameters2015
- Author(s)
  Isohashi F, Mabuchi S, Yoshioka Y, Seo Y, Suzuki O, Tamari K, Yamashita M, Unno H, Kinose Y, Kozasa K, Sumida I, Otani Y, Kimura T, Ogawa K.
- Organizer
  International congress of radiation research
- Place of Presentation
  Kyoto
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-25861097
[Presentation] Dose-volume analysis of predictors for chronic gastrointestinal complications in patients with cervical cancer treated with postoperative concurrent chemotherapy and whole-pelvic radiation therapy2015
- Author(s)
  礒橋文明、玉利慶介、高橋　豊、隅田伊織、鈴木　修、瀬尾雄二、吉岡靖生、小川和彦
- Organizer
  第28回日本放射線腫瘍学会
- Place of Presentation
  ベイシア文化ホール（群馬県・前橋市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-25861097
[Presentation] Dose-volume analysis of predictors for acute hematologic toxicity in patients with cervical cancer treated with postoperative pelvic radiation therapy and concurrent nedaplatin-based chemotherapy2014
- Author(s)
  Isohashi F, Yoshioka Y, Mabuchi S, Seo Y, Suzuki O, Sumida I, Otani Y, Kimura T, Ogawa K.
- Organizer
  ASTRO 56th annual meeting
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-25861097
[Presentation] 子宮頸癌に対する高線量率組織内照射2010
- Author(s)
  礒橋文明
- Organizer
  日本婦人科腫瘍学会
- Place of Presentation
  筑波(招待講演)
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21791193
[Presentation] Monotherapeutic high-dose-rate brachytherapy for prostate cancer : 15 years experience of Osaka University.2010
- Author(s)
  Konishi Y, Yoshioka Y, Sumida I, Takahashi Y, Ogata T, Isohashi F, Koizumi M, Inoue T.
- Organizer
  52^<nd> annual meeting of the American Society for Radiation Oncology
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21791193
[Presentation] 子宮頸癌術後照射における小腸に対する照射体積と急性・亜急性期の腸炎発生との関係2010
- Author(s)
  礒橋文明
- Organizer
  日本放射線腫瘍学会
- Place of Presentation
  千葉
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-21791193
[Presentation] 低酸素下のIGF刺激は小胞体ストレス反応を通して膵臓癌細胞の放射線感受性を上昇させる2009
- Author(s)
  礒橋文明
- Organizer
  第68回日本医学放射線学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-04-19
- Data Source
  KAKENHI-PROJECT-21791193
[Presentation] 再発子宮頸癌に対する高線量率組織内照射2009
- Author(s)
  礒橋文明
- Organizer
  第22回日本放射線腫瘍学会総会
- Place of Presentation
  京都
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-21791193

1. Tamari Keisuke (30718995)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. OGAWA Kazuhiko (40253984)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. SEO Yuji (00302000)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. HAYASHI Kazuhiko (70718981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ISHII Hideshi (10280736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Kim Yoon-Jeong (40574330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 秋野祐一 (00722323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 三浦幸子 (60597095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 田中真二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Isohashi Fumiaki 礒橋 文明

ISOHASHI Fumiaki 礒橋 文明

Research Projects

Research Products

Co-Researchers

Establishment of a functionally informed radiotherapy planning evaluation methodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Monitoring of residual and recurrence of cervical cancer after radiotherapy using blood liquid biopsy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The relationships between radioresistance and polyamine metabolism in cervical cancer stem cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of radiosensitizers targeting cancer stem cells in cervical cancer by using high throughput screening

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effectiveness of bone marrow sparing IMRT using FLT-PETPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Sequential analysis of the acute hypoxia with the irradiation for prostate cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Polyamine flux suppresses histone lysine demethylases and enhances ID1 expression in cancer stem cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dose-volume analysis of predictors for chronic gastrointestinal complications in patients with cervical cancer treated with postoperative concurrent chemotherapy and whole-pelvic radiation therapy2016

Author(s)

Journal Title

Data Source

[Journal Article] Intensity-modulated radiation therapy versus three-dimensional conformal radiation therapy with concurrent nedaplatin-based chemotherapy after radical hysterectomy for uterine cervical cancer: comparison of outcomes, complications, and dose-volume histogram parameters.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] What is the Optimum Minimum Segment Size Used in Step and Shoot IMRT for Prostate Cancer?2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Concurrent weekly nedaplatin, external beam radiotherapy and high-dose-rate barchytherapy in patients with FIGO stage IIIb cervical cancer : A comparison with a cohort treated by radiotherapy alone2010

Author(s)

Journal Title

Data Source

[Journal Article] Prognostic factors for survival in patients with recurrent cervical cancer previously treated with radiotherapy2010

Author(s)

Journal Title

Data Source

[Journal Article] Rectal dose and source strength of the high-dose-rate iridium-192 both affect late rectal bleeding after intracavitary radiation therapy for uterine cervical carcinoma2010

Author(s)

Journal Title

Data Source

[Journal Article] High-dose-rate interstitial brachytherapy for previously untreated cervical carcinoma2009

Author(s)

Journal Title

Data Source

[Journal Article] Correlation between dosimetric parameters and late rectal and urinary toxicities in patients treated with high-dose-rate brachytherapy used as monotherapy for prostate cancer.2009

Author(s)

Journal Title

Data Source

Isohashi Fumiaki 礒橋文明

ISOHASHI Fumiaki 礒橋文明