Kakehi Saori 筧佐織

… Alternative Names

KAKEHI Saori 筧佐織

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Researcher Number	00450560
Other IDs
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 特任助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 順天堂大学, 大学院医学研究科, 特任助教 2014 – 2020: 順天堂大学, 医学(系)研究科(研究院), 特任助教 2016: 順天堂大学, 医学(系)研究科(研究院), 助教 2015: 順天堂大学, 医学(系)研究科(研究院), その他 2015: 順天堂大学, 大学院医学(系)研究科(研究院), 特任助教 … More 2014: 順天堂大学, 医学研究科, 特任助教 2013: 順天堂大学, 医学(系)研究科(研究院), 研究員 2012 – 2013: 順天堂大学, 医学(系)研究科(研究院), その他 2012: 順天堂大学, 医学部, 研究員 2010: 順天堂大学, 医学研究科, 研究員 2010: Juntendo University, 医学部, 研究員 2009: Juntendo University, 大学院・医学研究科, 研究員 2008: Tokyo Metropolitan Institute of Gerontology, 東京都老人総合研究所, 研究員 2008: Tokyo Metropolitan Institute of Gerontology, 東京都老人総合研究所, 研究員 2007: Tokyo Metropolitan Institute of Gerontology, 東京都老人総合研究所, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Applied health science / Applied health science / Rehabilitation science/Welfare engineering / Sports science Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Applied health science / Health science and related fields / Applied health science
Keywords	Principal Investigator 骨格筋 / 不活動 / インスリン感受性 / 骨格筋細胞内脂質 / インスリン抵抗性 / 高脂肪 / Lipin1 / 細胞内脂質 / 高脂肪食 / 筋量 … More / 筋萎縮 / 細胞・組織 / 老化 / 組織 / 細胞 … More Except Principal Investigator インスリン抵抗性 / 骨格筋細胞内脂質 / 異所性脂肪 / メタボリックシンドローム / 糖尿病 / メタボロミクス / プロテオミクス / メタボローム解析 / リン酸化 / 廃用性筋萎縮 / プロテオーム解析 / 視床下部 / 2型糖尿病 / 脳インスリン抵抗性 / 脂肪負荷感受性 / 脂肪筋 / 脂肪肝 / 高脂肪食 / アスリートパラドックス / 運動 / インスリン感受性 / 骨格筋 / アスリートパラドクス / 非肥満 / 非肥満者 / インスリンクリアランス / 遺伝子発現 / 筋萎縮 / 血流制限 / インスリン分泌 / 飲酒 Less

Lipin1を中心とした骨格筋の質と量に与える影響における共通病態基盤の解明Principal Investigator
- Principal Investigator
  
  筧佐織
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Juntendo University
efinition of "brain insulin resistance" at the human hypothalamic nucleus level and its clinical application
- Principal Investigator
  
  Tamura Yoshifumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Juntendo University
Comprehensive study on skeletal muscle disorders caused by high-fat diet inactivity with a focus on the key molecule Lipin1.Principal Investigator
- Principal Investigator
  
  Kakehi Saori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Juntendo University
Omics analysis of skeletal muscle in a mouse model of disuse muscular atrophy.
- Principal Investigator
  
  三浦芳樹
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Juntendo University
Twenty-four hours physical inactivity induce insulin resistance in the muscle.Principal Investigator
- Principal Investigator
  
  Kakehi Saori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Juntendo University
Clinical significance and mechanism of fat load susceptibility
- Principal Investigator
  
  Tamura Yoshifumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Juntendo University
Research for unknown mechanism of insulin resistance in non-obese subject
- Principal Investigator
  
  Tamura Yoshifumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Health science and related fields
- Research Institution
  Juntendo University
Elucidation of the molecular mechanism of muscle insulin resistance induced by physical inactivity and establishment of prevention method.Principal Investigator
- Principal Investigator
  
  KAKEHI saori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Juntendo University
Elucidation of the athlete paradox and examination of clinical application
- Principal Investigator
  
  KAWAMORI ryuzo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Juntendo University
Research for unknown mechanism of insulin resistance in non-obese subject and its clinical application.
- Principal Investigator
  
  Tamura Yoshifumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Juntendo University
Inhibiting effect of blood flow restriction on skeletal muscle atrophy and investigation of related genes
- Principal Investigator
  
  SAKURABA KEISHOKU
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Juntendo University
Investigation for pathophysiology in latent phase of diabetes and development of new interventional method
- Principal Investigator
  
  KAWAMORI Ryuzo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Juntendo University
Mechanisms of insulin resistance after 24 hours physical inactivity in murine soleus muscle.Principal Investigator
- Principal Investigator
  
  KAKEHI SAORI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Juntendo University
Clarification of molecular mechanism in prevention of muscular atrophy by transient blood flow restriction.Principal Investigator
- Principal Investigator
  
  KAKEHI Saori
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Juntendo University
Development of safety training for elderly with elucidation of molecular mechanism on"KAATU " training.Principal Investigator
- Principal Investigator
  
  KAKEHI Saori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Sports science
- Research Institution
  Tokyo Metropolitan Institute of Gerontology

[Journal Article] Corrigendum: Playing basketball and volleyball during adolescence is associated with higher bone mineral density in old age: the Bunkyo Health Study2024
- Author(s)
  Otsuka Hikaru、Tabata Hiroki、Shi Huicong、Sugimoto Mari、Kaga Hideyoshi、Someya Yuki、Naito Hitoshi、Ito Naoaki、Abudurezake Abulaiti、Umemura Futaba、Tajima Tsubasa、Kakehi Saori、Yoshizawa Yasuyo、Ishijima Muneaki、Kawamori Ryuzo、Watada Hirotaka、Tamura Yoshifumi
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 15
- DOI
  10.3389/fphys.2024.1385648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11684
[Journal Article] Low Handgrip Strength (Possible Sarcopenia) With Insulin Resistance Is Associated With Type 2 Diabetes Mellitus2024
- Author(s)
  Tajima Tsubasa、Kaga Hideyoshi、Someya Yuki、Tabata Hiroki、Naito Hitoshi、Kakehi Saori、Ito Naoaki、Yamasaki Nozomu、Sato Motonori、Kadowaki Satoshi、Sugimoto Daisuke、Nishida Yuya、Kawamori Ryuzo、Watada Hirotaka、Tamura Yoshifumi
- Journal Title
  
  Journal of the Endocrine Society
  
  Volume: 8 Issue: 3
- DOI
  10.1210/jendso/bvae016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11684
[Journal Article] A chronic high‐fat diet does not exacerbate muscle atrophy in fast‐twitch skeletal muscle of aged mice2023
- Author(s)
  Tagawa Tsutomu、Eshima Hiroaki、Kakehi Saori、Kawamori Ryuzo、Watada Hirotaka、Tamura Yoshifumi
- Journal Title
  
  Experimental Physiology
  
  Volume: 1 Issue: 7 Pages: 1-1
- DOI
  10.1113/ep091106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K17745, KAKENHI-PROJECT-21K11684
[Journal Article] Fat Accumulation and Elevated Free Fatty Acid Are Associated With Age-Related Glucose Intolerance: Bunkyo Health Study2023
- Author(s)
  Naito Hitoshi、Kaga Hideyoshi、Someya Yuki、Tabata Hiroki、Kakehi Saori、Tajima Tsubasa、Ito Naoaki、Yamasaki Nozomu、Sato Motonori、Kadowaki Satoshi、Sugimoto Daisuke、Nishida Yuya、Kawamori Ryuzo、Watada Hirotaka、Tamura Yoshifumi
- Journal Title
  
  Journal of the Endocrine Society
  
  Volume: 8 Issue: 2
- DOI
  10.1210/jendso/bvad164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11684
[Journal Article] Physical inactivity induces insulin resistance in plantaris muscle through protein tyrosine phosphatase 1B activation in mice2023
- Author(s)
  Kakehi Saori、Tamura Yoshifumi、Ikeda Shin-ichi、Kaga Naoko、Taka Hikari、Nishida Yuya、Kawamori Ryuzo、Watada Hirotaka
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 14
- DOI
  10.3389/fphys.2023.1198390
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11752, KAKENHI-PROJECT-21K11684
[Journal Article] Playing basketball and volleyball during adolescence is associated with higher bone mineral density in old age: the Bunkyo Health Study2023
- Author(s)
  Otsuka Hikaru、Tabata Hiroki、Shi Huicong、Sugimoto Mari、Kaga Hideyoshi、Someya Yuki、Naito Hitoshi、Ito Naoaki、Abudurezake Abulaiti、Umemura Futaba、Tajima Tsubasa、Kakehi Saori、Yoshizawa Yasuyo、Ishijima Muneaki、Kawamori Ryuzo、Watada Hirotaka、Tamura Yoshifumi
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 14
- DOI
  10.3389/fphys.2023.1227639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K17644, KAKENHI-PROJECT-21K11684
[Journal Article] A Short-Term High-Fat Diet Worsens Insulin Sensitivity with Changes in Metabolic Parameters in Non-Obese Japanese Men2023
- Author(s)
  Satoshi Kadowaki , Yoshifumi Tamura , Daisuke Sugimoto , Hideyoshi Kaga , Ruriko Suzuki , Yuki Someya , Nozomu Yamasaki , Motonori Sato , Saori Kakehi , Akio Kanazawa , Ryuzo Kawamori and HirotakaWatada
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 4084. Issue: 12 Pages: 4084-4084
- DOI
  10.3390/jcm12124084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K16778, KAKENHI-PROJECT-21K11684
[Journal Article] Effects of exercise habits in adolescence and older age on sarcopenia risk in older adults: the Bunkyo Health Study2023
- Author(s)
  Tabata Hiroki、Otsuka Hikaru、Shi Huicong、Sugimoto Mari、Kaga Hideyoshi、Someya Yuki、Naito Hitoshi、Ito Naoaki、Abudurezake Abulaiti、Umemura Futaba、Kiya Mai、Tajima Tsubasa、Kakehi Saori、Yoshizawa Yasuyo、Kawamori Ryuzo、Watada Hirotaka、Tamura Yoshifumi
- Journal Title
  
  Journal of Cachexia, Sarcopenia and Muscle
  
  Volume: - Issue: 3 Pages: 1299-1311
- DOI
  10.1002/jcsm.13218
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K23261, KAKENHI-PROJECT-21K11684
[Journal Article] Prediabetes is an independent risk factor for sarcopenia in older men, but not in older women: the Bunkyo Health Study2022
- Author(s)
  Kaga H, Tamura Y, Someya Y, Naito H, Tabata H, Kakehi S, Yamasaki N, Sato M, Kadowaki S, Suzuki R, Sugimoto D, Kawamori R, Watada H.
- Journal Title
  
  J Cachexia Sarcopenia Muscle.
  
  Volume: 13 Issue: 6 Pages: 2835-2842
- DOI
  10.1002/jcsm.13074
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11684, KAKENHI-PROJECT-20K23261
[Journal Article] Impaired fatigue resistance, sarcoplasmic reticulum function, and mitochondrial activity in soleus muscle of db/db mice2022
- Author(s)
  Yamamoto H, Eshima H, Kakehi S, Kawamori R, Watada H, Tamura Y.
- Journal Title
  
  Physiol Rep.
  
  Volume: 10 Issue: 18
- DOI
  10.14814/phy2.15478
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11684, KAKENHI-PROJECT-22K17745, KAKENHI-PROJECT-21K21271
[Journal Article] Association of ALDH2 Genotypes and Alcohol Intake with Dietary Patterns: The Bunkyo Health Study2022
- Author(s)
  Sugimoto M, Tabata H, Kaga H, Someya Y, Kakehi S, Abudurezake A, Naito H, Ito N, Shi H, Otsuka H, Umemura F, Yoshizawa Y, Kawamori R, Watada H, Tamura Y.
- Journal Title
  
  Nutrients.
  
  Volume: 14 Issue: 22 Pages: 4830-4830
- DOI
  10.3390/nu14224830
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11684, KAKENHI-PROJECT-20K23261
[Journal Article] Short-term physical inactivity induces diacylglycerol accumulation and insulin resistance in muscle via lipin1 activation2021
- Author(s)
  Kakehi Saori、Tamura Yoshifumi、Ikeda Shin-ichi、Kaga Naoko、Taka Hikari、Ueno Noriko、Shiuchi Tetsuya、Kubota Atsushi、Sakuraba Keishoku、Kawamori Ryuzo、Watada Hirotaka
- Journal Title
  
  American Journal of Physiology-Endocrinology and Metabolism
  
  Volume: 321 Issue: 6 Pages: E766-E781
- DOI
  10.1152/ajpendo.00254.2020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09403, KAKENHI-PROJECT-18H03152, KAKENHI-PROJECT-18K07829, KAKENHI-PROJECT-19K11752, KAKENHI-PROJECT-20K09834, KAKENHI-PROJECT-21K06496, KAKENHI-PROJECT-21K11684, KAKENHI-PROJECT-18K19745
[Journal Article] A decrease in plasma glucose levels is required for increased endogenous glucose production with a single administration of a sodium‐glucose co‐transporter‐2 inhibitor tofogliflozin2021
- Author(s)
  Yamasaki、Tamura Y、Kaga H、Sato M、Kiya M、Kadowaki S、Suzuki R、Furukawa Y、Sugimoto D、Funayama T、Someya Y、Kakehi S、Nojiri S、Satoh H、Kawamori R、Watada H
- Journal Title
  
  Diabetes, Obesity and Metabolism
  
  Volume: 23 Issue: 5 Pages: 1092-1100
- DOI
  10.1111/dom.14312
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11654, KAKENHI-PROJECT-21K11684
[Journal Article] Adipose Insulin Resistance and Decreased Adiponectin Are Correlated With Metabolic Abnormalities in Nonobese Men2021
- Author(s)
  Kiya M、Tamura Y、Takeno K、Someya Y、Kakehi S、Sato M、Yamasaki N、Kadowaki S、Suzuki R、Furukawa Y、Sugimoto D、Kaga H、Funayama T、Nishitani-Y M、Shimada K、Daida H、Aoki S、Satoh H、Kawamori R、Watada H
- Journal Title
  
  The Journal of Clinical Endocrinology & Metabolism
  
  Volume: 106 Issue: 5 Pages: e2228-e2238
- DOI
  10.1210/clinem/dgab037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11654, KAKENHI-PROJECT-21K11684
[Journal Article] ALDH2 rs671 Is Associated With Elevated FPG, Reduced Glucose Clearance and Hepatic Insulin Resistance in Japanese Men.2021
- Author(s)
  Takeno K, Tamura Y, Kakehi S, Kaga H, Kawamori R, Watada H.
- Journal Title
  
  J Clin Endocrinol Metab.
  
  Volume: 106(9) Issue: 9 Pages: e3573-e3581
- DOI
  10.1210/clinem/dgab324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11684
[Journal Article] Short-Term SGLT2 Inhibitor Administration Does Not Alter Systemic Insulin Clearance in Type 2 Diabetes2021
- Author(s)
  Sato M、Tamura Y、Kaga H、Yamasaki N、Kiya M、Kadowaki S、Sugimoto D、Funayama T、Someya Y、Kakehi S、Nojiri S、Satoh H、Kawamori R、Watada H
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 9 Pages: 1154-1154
- DOI
  10.3390/biomedicines9091154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11654, KAKENHI-PROJECT-21K11684
[Journal Article] Maintenance of contractile force and increased fatigue resistance in slow-twitch skeletal muscle of mice fed a high-fat diet2021
- Author(s)
  Eshima Hiroaki、Tamura Yoshifumi、Kakehi Saori、Kakigi Ryo、Kawamori Ryuzo、Watada Hirotaka
- Journal Title
  
  Journal of Applied Physiology
  
  Volume: 130 Issue: 3 Pages: 528-536
- DOI
  10.1152/japplphysiol.00218.2020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11526, KAKENHI-PROJECT-21K11684
[Journal Article] Author Correction: Both higher fitness level and higher current physical activity level may be required for intramyocellular lipid accumulation in non-athlete men2021
- Author(s)
  Yamasaki N, Tamura Y, Takeno K, Kakehi S, Someya Y, Funayama T, Furukawa Y, Kaga H, Suzuki R, Sugimoto D, Kadowaki S, Sato M, Nakagata T, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Satoh H, Kawamori R, Watada H.
- Journal Title
  
  Sci Rep
  
  Volume: 25 Issue: 1 Pages: 7304-7304
- DOI
  10.1038/s41598-021-86892-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11029, KAKENHI-PROJECT-20K11654
[Journal Article] Characteristics associated with elevated 1-h plasma glucose levels during a 75-g oral glucose tolerance test in non-obese Japanese men.2020
- Author(s)
  Sato M, Tamura Y, Someya Y, Takeno K, Kaga H, Kadowaki S, Sugimoto D, Kakehi S, Funayama T, Furukawa Y, Suzuki R, Nakagata T, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Sato H, Kawamori R, Watada H.
- Journal Title
  
  J Diabetes Investig
  
  Volume: . Issue: 6 Pages: 1520-1523
- DOI
  10.1111/jdi.13245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11029, KAKENHI-PROJECT-20K11654
[Journal Article] Effects of blood flow restriction on muscle size and gene expression in muscle during immobilization: A pilot study2020
- Author(s)
  Kakehi S, Tamura Y, Kubota A, Takeno K, Kawaguchi M, Sakuraba K, Kawamori R, Watada H.
- Journal Title
  
  Physiol Rep.
  
  Volume: 8 Issue: 14
- DOI
  10.14814/phy2.14516
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11029
[Journal Article] A chronic high-fat diet exacerbates contractile dysfunction with impaired intracellular Ca 2+ release capacity in the skeletal muscle of aged mice2020
- Author(s)
  Eshima H, Tamura Y, Kakehi S, Kakigi R, Hashimoto R, Funai K, Kawamori R, Watada H.
- Journal Title
  
  J Appl Physiol (1985).
  
  Volume: 128 Issue: 5 Pages: 1153-1162
- DOI
  10.1152/japplphysiol.00530.2019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11029
[Journal Article] Both higher fitness level and higher current physical activity level may be required for intramyocellular lipid accumulation in non-athlete men.2020
- Author(s)
  Yamasaki N, Tamura Y, Takeno K, Kakehi S, Someya Y, Funayama T, Furukawa Y, Kaga H, Suzuki R, Sugimoto D, Kadowaki S, Sato M, Nakagata T, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Sato H, Kawamori R, Watada H.
- Journal Title
  
  Sci Rep.
  
  Volume: 10 Issue: 1 Pages: 4102-4102
- DOI
  10.1038/s41598-020-61080-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11029, KAKENHI-PROJECT-20K11654
[Journal Article] Shape of the glucose response curve during an oral glucose tolerance test is associated with insulin clearance and muscle insulin sensitivity in healthy non-obese men.2020
- Author(s)
  Kaga H, Tamura Y, Takeno K, Kakehi S, Someya Y, Funayama T, Furukawa Y, Suzuki R, Sugimoto D, Kadowaki S, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Giacca A, Sato H, Kawamori R, Watada H.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: . Issue: 4 Pages: 874-877
- DOI
  10.1111/jdi.13227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11029, KAKENHI-PROJECT-20K11654
[Journal Article] Decreased Muscle Strength of Knee Flexors is Associated with Impaired Muscle Insulin Sensitivity in Non-Diabetic Middle-Aged Japanese Male Subjects2020
- Author(s)
  Someya Y, Tamura Y, Takeno K, Kakehi S, Funayama T, Furukawa Y, Eshima H, Watanabe K, Kurihara T, Yanagiya T, Kaga H, Suzuki R, Sugimoto D, Kadowaki S, Kawamori R, Watada H.
- Journal Title
  
  Diabetes Ther.
  
  Volume: 11 Issue: 10 Pages: 2401-2410
- DOI
  10.1007/s13300-020-00895-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11029
[Journal Article] Dysfunction of muscle contraction with impaired intracellular Ca2+ handling in skeletal muscle and the effect of exercise training in male db/db mice2019
- Author(s)
  Eshima Hiroaki、Tamura Yoshifumi、Kakehi Saori、Nakamura Kyoko、Kurebayashi Nagomi、Murayama Takashi、Kakigi Ryo、Sakurai Takashi、Kawamori Ryuzo、Watada Hirotaka
- Journal Title
  
  Journal of Applied Physiology
  
  Volume: 126 Issue: 1 Pages: 170-182
- DOI
  10.1152/japplphysiol.00048.2018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-18K11029
[Journal Article] Higher C-Peptide Level During Glucose Clamp Is Associated With Muscle Insulin Resistance in Nonobese Japanese Men.2019
- Author(s)
  Kaga H, Tamura Y, Takeno K, Kakehi S, Someya Y, Funayama T, Furukawa Y, Suzuki R, Sugimoto D, Kadowaki S, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Giacca A, Kanazawa A, Kawamori R, Watada H.
- Journal Title
  
  J Endocr Soc
  
  Volume: 3 Issue: 10 Pages: 1847-1857
- DOI
  10.1210/js.2019-00167
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11029
[Journal Article] Fatty Liver Has Stronger Association With Insulin Resistance Than Visceral Fat Accumulation in Nonobese Japanese Men.2019
- Author(s)
  Kadowaki S, Tamura Y, Someya Y, Takeno K, Kaga H, Sugimoto D, Kakehi S, Funayama T, Furukawa Y, Suzuki R, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Kanazawa A, Kawamori R, Watada H.
- Journal Title
  
  J Endocr Soc.
  
  Volume: 3 Issue: 7 Pages: 1409-1416
- DOI
  10.1210/js.2019-00052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11029
[Journal Article] Three days of a eucaloric, low-carbohydrate/high-fat diet increases insulin clearance in healthy non-obese Japanese men.2019
- Author(s)
  Suzuki R, Tamura Y, Takeno K, Kakehi S, Funayama T, Furukawa Y, Kaga H, Sugimoto D, Kadowaki S, Someya Y, Kanazawa A, Kawamori R, Watada H.
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Issue: 1 Pages: 3857-3857
- DOI
  10.1038/s41598-019-40498-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11029
[Journal Article] Clinical Features of Nonobese, Apparently Healthy, Japanese Men With Reduced Adipose Tissue Insulin Sensitivity.2019
- Author(s)
  Sugimoto D, Tamura Y, Takeno K, Kaga H, Someya Y, Kakehi S, Funayama T, Furukawa Y, Suzuki R, Kadowaki S, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Kanazawa A, Kawamori R, Watada H.
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 104 Issue: 6 Pages: 2325-2333
- DOI
  10.1210/jc.2018-02190
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11029
[Journal Article] Correlates of insulin clearance in apparently healthy non-obese Japanese men.2017
- Author(s)
  Kaga H, Tamura Y, Takeno K, Kakehi S, Funayama T, Furukawa Y, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Giacca A, Kanazawa A, Kawamori R, Watada H.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 1462-1462
- DOI
  10.1038/s41598-017-01469-x
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26282197, KAKENHI-PROJECT-15H03097, KAKENHI-PROJECT-15K01729
[Journal Article] Effects of alcohol abstinence on glucose metabolism in Japanese men with elevated fasting glucose: A pilot study.2017
- Author(s)
  Funayama T, Tamura Y, Takeno K, Kawaguchi M, Kakehi S, Watanabe T, Furukawa Y, Kaga H, Yamamoto R, Kanazawa A, Fujitani Y, Kawamori R, Watada H.
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Issue: 1 Pages: 40277-40277
- DOI
  10.1038/srep40277
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03097, KAKENHI-PROJECT-26282197, KAKENHI-PROJECT-15K01729, KAKENHI-PROJECT-16K09765
[Journal Article] Long-term, but not short-term high-fat diet induces fiber composition changes and impaired contractile force in mouse fast-twitch skeletal muscle2017
- Author(s)
  Eshima H,Tamura Y, Kakehi S, Kurebayashi N, Murayama T, Nakamura K, Kakigi R,Okada T,Sakurai T, Kawamori R, Watada H
- Journal Title
  
  Physiological reports
  
  Volume: 5 Issue: 7 Pages: e13250-e13250
- DOI
  10.14814/phy2.13250
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J11193, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-15H03097, KAKENHI-PROJECT-15K01729
[Journal Article] Impaired peripheral insulin sensitivity in non-obese Japanese patients with type 2 diabetes mellitus and fatty liver.2017
- Author(s)
  Furukawa Y, Tamura Y, Takeno K, Funayama T, Kaga H, Suzuki R, Watanabe T, Kakehi S, Kanazawa A, Kawamori R, Watada H.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: 印刷中 Issue: 3 Pages: 529-535
- DOI
  10.1111/jdi.12731
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H03097
[Journal Article] Characteristics of Glucose Metabolism in Underweight Japanese Women.2017
- Author(s)
  Someya Y, Tamura Y, Suzuki R, Kaga H, Kadowaki S, Sugimoto D, Kakehi S, Funayama T, Furukawa Y, Takeno K, Sato J, Kanazawa A, Kawamori R, Watada H.
- Journal Title
  
  J Endocr Soc.
  
  Volume: 2(3) Issue: 3 Pages: 279-289
- DOI
  10.1210/js.2017-00418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03097
[Journal Article] Relation Between Insulin Sensitivity and Metabolic Abnormalities in Japanese Men With BMI of 23-25 kg/m2.2016
- Author(s)
  Takeno K, Tamura Y, Kawaguchi M, Kakehi S, Watanabe T, Funayama T, Furukawa Y, Kaga H, Yamamoto R, Kim M, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Taka H, Fujimura T, Sawada SS, Giacca A, Kanazawa A, Fujitani Y, Kawamori R, Watada H.
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 101 Pages: 3676-3684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01729
[Journal Article] Increased intramyocellular lipid/impaired insulin sensitivity is associated with altered lipid metabolic genes in muscle of high responders to a high-fat diet2016
- Author(s)
  1.Kakehi S, Tamura Y, Takeno K, Sakurai Y, Kawaguchi M, Watanabe T, Funayama T, Sato F, Ikeda S, Kanazawa A, Fujitani Y, Kawamori R, Watada H
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 310(1)
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25350899
[Journal Article] Relation Between Insulin Sensitivity and Metabolic Abnormalities in Japanese Men With BMI of 23-25 kg/m2.2016
- Author(s)
  Takeno K, Tamura Y, Kawaguchi M, Kakehi S, Watanabe T, Funayama T, Furukawa Y, Kaga H, Yamamoto R, Kim M, Nishitani-Yokoyama M, Shimada K, Daida H, Aoki S, Taka H, Fujimura T, Sawada SS, Giacca A, Kanazawa A, Fujitani Y, Kawamori R, Watada H.
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 101 Pages: 3676-3684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03097
[Journal Article] Increased intramyocellular lipid/impaired insulin sensitivity is associated with altered lipid metabolic genes in muscle of high responders to a high-fat diet.2016
- Author(s)
  Kakehi S, Tamura Y, Takeno K, Sakurai Y, Kawaguchi M, Watanabe T, Funayama T, Sato F, Ikeda S, Kanazawa A, Fujitani Y, Kawamori R, Watada H.
- Journal Title
  
  Am J Physiol Endocrinol Metab.
  
  Volume: 310 Issue: 1 Pages: 32-40
- DOI
  10.1152/ajpendo.00220.2015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01729, KAKENHI-PROJECT-15H03097, KAKENHI-PROJECT-25350901, KAKENHI-PROJECT-25461364
[Journal Article] TBC1D4/AS160のSNPは骨格筋インスリン抵抗性、2型糖尿病を規定する2015
- Author(s)
  筧　佐織、田村　好史
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 41 Pages: 59-62
- NAID
  40020553974
- Data Source
  KAKENHI-PROJECT-15K01729
[Journal Article] TBC1D4/AS160のSNPは骨格筋インスリン抵抗性、2型糖尿病を規定する2015
- Author(s)
  筧　佐織、田村　好史
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 41(1) Pages: 59-62
- NAID
  40020553974
- Data Source
  KAKENHI-PROJECT-25350899
[Journal Article] Effects of sitagliptin on ectopic fat contents and glucose metabolism in type 2 diabetic patients with fatty liver: A pilot study2014
- Author(s)
  Watanabe T, Tamura Y, Kakehi S, Funayama T, Takeno K, Kawaguchi M, Yamamoto L, Sato F, Ikeda S, Taka H, Fujimura T, Fujitani Y, Kawamori R, Watada H
- Journal Title
  
  J Diabetes Invest
  
  Volume: Mar;6(2) Issue: 2 Pages: 164-72
- DOI
  10.1111/jdi.12262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500867, KAKENHI-PROJECT-25350899, KAKENHI-PROJECT-25350901, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-15H03097, KAKENHI-PROJECT-25430140
[Journal Article] Association between expression of FABPpm in skeletal muscle and insulin sensitivity in intramyocellular-lipid-accumulated non-obese men2014
- Author(s)
  Kawaguchi M, Tamura Y, Kakehi S, Takeno K, Sakurai Y, Watanabe T, Funayama T, Sato F, Ikeda S, Ogura Y, Saga N, Naito H, Fujitani Y, Kanazawa A, Kawamori R, Watada
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: Sep;99(9) Issue: 9 Pages: 3343-52
- DOI
  10.1210/jc.2014-1896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500867, KAKENHI-PROJECT-25350899, KAKENHI-PROJECT-25350901
[Journal Article] 骨格筋における異所性脂肪とインスリン抵抗性2013
- Author(s)
  田村好史、筧佐織、竹野景海
- Journal Title
  
  肥満研究
  
  Volume: 19 Pages: 175-180
- Data Source
  KAKENHI-PROJECT-25350899
[Journal Article] 骨格筋における異所性脂肪とインスリン抵抗性2013
- Author(s)
  田村好史、筧　佐織、竹野景海
- Journal Title
  
  肥満研究
  
  Volume: 19 Pages: 175-180
- Data Source
  KAKENHI-PROJECT-24500867
[Journal Article] Exercise-induced enhancement of insulin sensitivity is associated with accumulation of M2-polarized macrophages in mouse skeletal muscle.2013
- Author(s)
  Ikeda S1, Tamura Y, Kakehi S, Takeno K, Kawaguchi M, Watanabe T, Sato F, Ogihara T, Kanazawa A, Fujitani Y, Kawamori R, Watada H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 441 Pages: 36-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500867
[Journal Article] 長期療養高齢者と高齢者医療を担う医師の役割2009
- Author(s)
  高橋龍太郎、筧佐織
- Journal Title
  
  日本老年医学会雑誌 Vol.46
  
  Pages: 134-136
- NAID
  10024964052
- Data Source
  KAKENHI-PROJECT-21700548
[Journal Article] Determinants of intramyocellular lipid accumulation after dietary fat loading in non-obese men.
- Author(s)
  Sakurai Y, Tamura Y, Takeno K, Kumashiro N, Sato F, Kakehi S, Ikeda S, Katamoto S, Ogura Y, Saga N, Naito H, Fujitani Y, Hirose T, Kawamori R, Watada H
- Journal Title
  
  J Diabetes Invest. in press
- Data Source
  KAKENHI-PROJECT-21700548
[Journal Article] Determinants of intramyocellular lipid accumulation after dietary fat loading in non-obese men
- Author(s)
  Sakurai Y, Tamura Y, Takeno K, Kumashiro N, Sato F, Kakehi S, Ikeda S, Katamoto S, Ogura Y, Saga N, Naito H, Fujitani Y, Hirose T, Kawamori R, Watada H
- Journal Title
  
  J Diabetes Invest
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] The Significance of Physical Inactivity in Nonobese Metabolic Diseases.2024
- Author(s)
  筧佐織
- Organizer
  日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K11684
[Presentation] Higher relative abundance of bacteroidetes in gut microbiota is associated with decreased insulin clearance and insulin sensitivity after a short-term high-calorie, high-fat diet in healthy men.2020
- Author(s)
  Kadowaki S, Tamura Y, Sugimoto D, Someya Y, Kaga H, Suzuki R, Kakehi S, Yamasaki N, Sato M, Kanazawa A, Kawamori R, Watada H.
- Organizer
  80th American Diabetes Association, Chicago　(USA), 2020.6.12-16. （ Poster,　Virtual meeting）.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03196
[Presentation] Short-term overfeeding with dairy fat impairs insulin sensitivity in muscle and liver but increases adipose tissue insulin sensitivity and suppresses postprandial glucose rise in healthy non-obese men.2020
- Author(s)
  Sugimoto D, Tamura Y, Kadowaki S, Someya Y, Kaga H, Suzuki R, Kakehi S, Yamasaki N, Sato M, Kanazawa A, Kawamori R, Watada H.
- Organizer
  80th American Diabetes Association, Chicago　(USA), 2020.6.12-16. （ Poster,　Virtual meeting）.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03196
[Presentation] Effects of exercise intensity on the insulin sensitivity and lipid composition in skeletal muscle under the same calorie consumption exercise.2017
- Author(s)
  Saori Kakehi, Yoshifumi Tamura, Takashi Funayama, Kageumi Takeno, Ryuzo Kawamori and Hirotaka Watada
- Organizer
  Cell simposia Exercises metabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01729
[Presentation] Effects of exercise intensity on the insulin sensitivity and lipid composition in skeletal muscle under the same calorie consumption exercise.2017
- Author(s)
  Saori Kakehi, Yoshifumi Tamura, Takashi Funayama, Kageumi Takeno, Ryuzo Kawamori and Hirotaka Watada
- Organizer
  The 3rd congress International academy of sportology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01729
[Presentation] Effects of difference in exercise intensity under the same energy consumption on the phospholipid composition in muscle2017
- Author(s)
  Saori Kakehi, Yoshifumi Tamura, Takashi Funayama, Kageumi Takeno, Ryuzo Kawamori and Hirotaka Watada
- Organizer
  Cell symposia Exercises Metabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03097
[Presentation] 高脂肪食・不活動による骨格筋インスリン抵抗性発生メカニズム2016
- Author(s)
  筧　佐織
- Organizer
  第59回日本糖尿尿病学会年次学術集会シンポジウム
- Place of Presentation
  京都
- Year and Date
  2016-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-15H03097
[Presentation] 高脂肪食・不活動による骨格筋インスリン抵抗性発生メカニズム2016
- Author(s)
  筧　佐織
- Organizer
  第59回日本糖尿尿病学会年次学術集会シンポジウム
- Place of Presentation
  京都
- Year and Date
  2016-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-15K01729
[Presentation] Physical inactivity and high fat diet additively induce diacylglycerol accumulation and insulin resistance in muscle2016
- Author(s)
  Saori Kakehi, Yoshifumi Tamura, Shin-ichi Ikeda, Naoko Kaga, Ryuzo Kawamori, Hirotaka Wata
- Organizer
  76th American Diabetes Association Scientific Sessions
- Place of Presentation
  New Orleans, Louisiana
- Year and Date
  2016-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01729
[Presentation] Physical inactivity and high fat diet additively induce diacylglycerol accumulation and insulin resistance2016
- Author(s)
  Saori Kakehi, Yoshifumi Tamura, Shin-ichi Ikeda, Naoko Kaga, Ryuzo Kawamori, Hirotaka Wata
- Organizer
  76th American Diabetes Association Scientific Sessions
- Place of Presentation
  New Orleans, Louisiana
- Year and Date
  2016-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03097
[Presentation] 高脂肪・不活動による骨格筋インスリン抵抗性惹起メカニズム2015
- Author(s)
  筧　佐織、田村　好史、池田　真一、加賀　直子、河盛　隆造、綿田　裕孝
- Organizer
  分子糖尿病学シンポジウム
- Place of Presentation
  東京都千代田区、丸ビルホール&コンファレンススクエア
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-15K01729
[Presentation] 高脂肪・不活動による骨格筋インスリン抵抗性惹起メカニズム2015
- Author(s)
  5.筧　佐織、田村　好史、池田　真一、加賀　直子、河盛　隆造、綿田　裕孝
- Organizer
  分子糖尿病学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] Intramyocellular lipid accumulation after high-fat diet is associated with the gene expression involved in lipid metabolism in skeletal muscle of non-obese men2015
- Author(s)
  3.Kakehi S, Tamura Y, Takeno K, Sakurai Y, Kawaguchi M, Watanabe T, Funayama T, Sato F, Ikeda S, Kanazawa A, Fujitani Y, Kawamori R, Watada H
- Organizer
  2nd Congress, International Academy of Sportology
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2015-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] Intramyocellular lipid accumulation after high-fat diet is associated with the gene expression involved in lipid metabolism in skeletal muscle of non-obese men2015
- Author(s)
  Kakehi S, Tamura Y, Takeno K, Sakurai Y, Kawaguchi M, Watanabe T, Funayama T, Sato F, Ikeda S, Kanazawa A, Fujitani Y, Kawamori R, Watada H
- Organizer
  2nd Congress, International Academy of Sportology.
- Place of Presentation
  東京都文京区、順天堂大学
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K01729
[Presentation] 24時間の脚ギプス固定は、骨格筋細胞内のジアシルグリセロールを増加させ、インスリン抵抗性を惹起する2015
- Author(s)
  筧　佐織、田村　好史、池田　真一、河盛　隆造、綿田　裕孝
- Organizer
  第70回体力医学会大会
- Place of Presentation
  和歌山、和歌山市、和歌山県民文化会館
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-15H03097
[Presentation] Intramyocellular lipid accumulation after high-fat diet is associated with the gene expression involved in lipid metabolism in skeletal muscle of non-obese men2015
- Author(s)
  Kakehi S, Tamura Y, Takeno K, Sakurai Y, Kawaguchi M, Watanabe T, Funayama T, Sato F, Ikeda S, Kanazawa A, Fujitani Y, Kawamori R, Watada H
- Organizer
  2nd Congress, International Academy of Sportology.
- Place of Presentation
  東京、文京区、順天堂大学
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15H03097
[Presentation] 24時間の脚ギプス固定は、骨格筋細胞内のジアシルグリセロールを増加させ、インスリン抵抗性を惹起する2015
- Author(s)
  筧　佐織、田村　好史、池田　真一、河盛　隆造、綿田　裕孝
- Organizer
  第70回体力医学会大会
- Place of Presentation
  和歌山県和歌山市、和歌山県民文化会館
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-15K01729
[Presentation] Mechanisums of insulin resistance after 24hours physical inactivity in murine soleus muscle2015
- Author(s)
  Kakehi S, Tamura Y, Ikeda S, Kawamori R, Watada H
- Organizer
  62nd Annual Meeting of American College of Sports Medicine.
- Place of Presentation
  サンディエゴ、アメリカ合衆国
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-15H03097
[Presentation] Physical inactivity and high fat diet synergistically enhance the accumulation of intramyocellular diacylglycerol and induce insulin resistance in murine soleus muscle2015
- Author(s)
  Kakehi S, Tamura Y, Kawamori R, Watada H
- Organizer
  Cell Symposia: Exercise Metabolism.
- Place of Presentation
  アムステルダム、オランダ
- Year and Date
  2015-07-12
- Data Source
  KAKENHI-PROJECT-15K01729
[Presentation] Physical inactivity and high fat diet synergistically enhance the accumulation of intramyocellular diacylglycerol and induce insulin resistance in murine soleus muscle2015
- Author(s)
  Kakehi S, Tamura Y, Kawamori R, Watada H
- Organizer
  Cell Symposia: Exercise Metabolism.
- Place of Presentation
  アムステルダム、オランダ
- Year and Date
  2015-07-12
- Data Source
  KAKENHI-PROJECT-15H03097
[Presentation] Mechanisums of insulin resistance after 24hours physical inactivity in murine soleus muscle2015
- Author(s)
  Kakehi S, Tamura Y, Ikeda S, Kawamori R, Watada H.
- Organizer
  62nd Annual Meeting of American College of Sports Medicine.
- Place of Presentation
  サンディエゴ、アメリカ合衆国
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-15K01729
[Presentation] Physical inactivity and high fat diet synergistically enhance the accumulation of intramyocellular diacylglycerol and induce insulin resistance in murine soleus muscle2015
- Author(s)
  2.Kakehi S, Tamura Y, Kawamori R, Watada H
- Organizer
  Cell Symposia: Exercise Metabolism
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2015-07-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] 24時間の脚ギプス固定は、骨格筋細胞内のジアシルグリセロールを増加させ、インスリン抵抗性を惹起する2015
- Author(s)
  4.筧　佐織、田村　好史、池田　真一、河盛　隆造、綿田　裕孝
- Organizer
  第70回体力医学会大会
- Place of Presentation
  和歌山
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] Mechanisums of insulin resistance after 24hours physical inactivity in murine soleus muscle2015
- Author(s)
  Kakehi S, Tamura Y, Ikeda S, Kawamori R, Watada H
- Organizer
  62nd Annual Meeting of American College of Sports Medicine
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] 高脂肪・不活動による骨格筋インスリン抵抗性惹起メカニズム2015
- Author(s)
  筧　佐織、田村　好史、池田　真一、加賀　直子、河盛　隆造、綿田　裕孝
- Organizer
  分子糖尿病学シンポジウム
- Place of Presentation
  東京、千代田区、丸ビルホール&コンファレンススクエア
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-15H03097
[Presentation] Physical inactivity and high fat diet synergistically enhance the accumulation of intramyocellular diacylglycerol and induce insulin resistance in murine soleus muscle.2013
- Author(s)
  Kakehi S, Tamura Y, Ikeda S, Kawamori R,Watada H
- Organizer
  18th Annual Congress of the European college of sports science
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] Physical inactivity and high fat diet synergistically enhance the accumulation of intramyocellular diacylglycerol and induce insulin resistance in murine soleus muscle.2013
- Author(s)
  Kakehi S, Tamura Y, Ikeda S, Kawamori R,Watada H
- Organizer
  American Diabetes Association 73st scientific sessions
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] Physical inactivity and high fat diet synergistically enhance the accumulation of intramyocellular diacylglycerol and induce insulin resistance in murine soleus muscle.2013
- Author(s)
  Kakehi S, Tamura Y, Ikeda S, Kawamori R,Watada H
- Organizer
  18th Annual Congress of the European college of sports science
- Place of Presentation
  Barcelona
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] 高脂肪食・不活動による骨格筋インスリン抵抗性発生メカニズム2013
- Author(s)
  筧佐織、田村好史、池田真一、河盛隆造、綿田裕孝
- Organizer
  第68回日本体力医学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] 高脂肪食・不活動による骨格筋インスリン抵抗性発生メカニズム2013
- Author(s)
  筧佐織、田村好史、池田真一、河盛隆造、綿田裕孝
- Organizer
  第34回日本肥満学会/APDO symposium 2013
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] 高脂肪食・不活動による骨格筋インスリン抵抗性発生メカニズム2013
- Author(s)
  筧　佐織、田村　好史、池田　真一、河盛　隆造、綿田　裕孝
- Organizer
  第34回日本肥満学会/APDO symposium 2013
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] 高脂肪食・不活動による骨格筋インスリン抵抗性発生メカニズム2013
- Author(s)
  筧　佐織、田村　好史、池田　真一、河盛　隆造、綿田　裕孝
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] 高脂肪食・不活動による骨格筋インスリン抵抗性発生メカニズム2013
- Author(s)
  筧　佐織、田村　好史、池田　真一、河盛　隆造、綿田　裕孝
- Organizer
  第68回日本体力医学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] 高脂肪食・不活動による骨格筋インスリン抵抗性発生メカニズム2013
- Author(s)
  筧佐織、田村好史、池田真一、河盛隆造、綿田裕孝
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] Physical inactivity and high fat diet synergistically enhance the accumulation of intramyocellular diacylglycerol and induce insulin resistance in murine soleus muscle.2013
- Author(s)
  Kakehi S, Tamura Y, Ikeda S, Kawamori R,Watada H
- Organizer
  American Diabetes Association 73st scientific sessions
- Place of Presentation
  Chicago, IL, US
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] 高脂肪食・不活動による骨格筋インスリン抵抗性発生メカニズム2012
- Author(s)
  筧　佐織
- Organizer
  第4回分子骨格筋代謝研究会
- Place of Presentation
  岐阜
- Invited
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] Characteristics of non-obese japanese men with muscle and/or liver insulin resistance.2012
- Author(s)
  Takeno K, Tamura Y, Kawaguchi M, Watanabe T, Funayama T, Sakurai Y, Sato F, Yamamoto R, Kim M, Kakehi S, Ikeda S, Giacca A, Fujitani Y, Hirose T, Kawamori R,Watada H
- Organizer
  American Diabetes Association 72st scientific sessions
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] Physical inactivity and high fat diet synergically induce insulin resistance in skeletal muscle through PTP1B activation.2012
- Author(s)
  Kakehi S, Tamura Y, Takeno K, Kawaguchi M, Watanabe T, Funayama T, Sato F, Ikeda S, Fujitani Y, Kawamori R,Watada H
- Organizer
  American Diabetes Association 72st scientific sessions
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] 高脂肪食・不活動による骨格筋インスリン抵抗性発生メカニズム2012
- Author(s)
  筧　佐織、田村　好史、池田　真一、河盛　隆造、綿田　裕孝
- Organizer
  第66回日本体力医学会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] シダグリプチンが異所性脂肪蓄積、糖代謝に与える効果2012
- Author(s)
  田村好史, 渡邉隆宏, 船山崇, 竹野景海, 川口美奈子, 筧佐織, 山本理紗子, 藤谷与士夫, 弘世貴久, 河盛隆造,綿田裕孝
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] 異所性脂肪蓄積とインスリン抵抗性2010
- Author(s)
  田村好史, 櫻井裕子, 竹野景海, 筧佐織, 池田真一, 川口美奈子, 渡邉隆宏, 佐藤文彦, 河盛隆造, 綿田裕孝
- Organizer
  Advans研究会
- Place of Presentation
  千葉県木更津市
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] Susceptible Factors for Intramyocellular Lipid Accumulation by Dietary Fat Loading in Non-Obese Men2010
- Author(s)
  Sakurai Y, Tamura Y, Takeno K, Kumashiro N, Sato F, Ikeda S, Kakehi S, Katamoto S, Naito H, Saga N, Ogura Y, Hirose T, Fujitani Y, Watada H
- Organizer
  American Diabetes Association 70^<th> Scientific sessions
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] ヒトにおける高脂肪食負荷が骨格筋細胞内脂質蓄積とインスリン感受性に与える影響とその規定因子の解明2010
- Author(s)
  櫻井裕子, 田村好史, 竹野景海, 熊代尚紀, 佐藤文彦, 池田真一, 筧佐織, 形本静夫, 内藤久士, 小倉裕司, 佐賀典生, 弘世貴久, 綿田裕孝, 河盛隆造
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山県岡山市
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] 筋サイズ並びに筋糖代謝に対するPKCδの関与の検討2010
- Author(s)
  池田真一、田村好史、筧佐織、綿田裕孝、河盛隆造
- Organizer
  第65回日本体力医学会
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] 脂肪負荷感受性の規定因子の解明2010
- Author(s)
  筧佐織、田村好史、池田真一、綿田裕孝、河盛隆造
- Organizer
  第65回日本体力医学会
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] 廃用性筋萎縮に対するPKCδの関与の検討2009
- Author(s)
  池田真一、田村好史、筧佐織、綿田裕孝、河盛隆造
- Organizer
  第64回日本体力医学会
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] ヒトにおける高脂肪食負荷が、骨格筋細胞内脂質蓄積とインスリン抵抗性発症に与える影響とその規定因子2009
- Author(s)
  田村好史, 櫻井裕子, 竹野景海, 熊代尚記, 池田真一, 筧佐織, 綿田裕孝, 河盛隆造
- Organizer
  第59回日本体質医学会総会東京都千代田区(日本),日本体質医学会
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] 筋インスリン抵抗性に対する高脂肪食と身体活動量の作用2009
- Author(s)
  筧佐織、田村好史、池田真一、綿田裕孝、河盛隆造
- Organizer
  第64回日本体力医学会
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] Effects of high fat diet on intramyocellular lipid and insulin resistance.2009
- Author(s)
  Sakurai Y, Tamura Y, Takeno K, Kumashiro N, Ikeda S, Kakehi S, Watada H, Kawamori R
- Organizer
  The First Asia-Pacific Conference on Health Promotion and Education
- Place of Presentation
  Chiba, Japan
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] 筋インスリン抵抗性に対する高脂肪食と身体活動量の作用2009
- Author(s)
  筧佐織
- Organizer
  第64回日本体力医学会
- Place of Presentation
  新潟
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] ヒトにおける高脂肪食負荷が、骨格筋細胞内脂質蓄積とインスリン抵抗性発症に与える影響とその規定因子2009
- Author(s)
  櫻井裕子, 田村好史, 竹野景海, 熊代尚記, 池田真一, 筧佐織, 綿田裕孝, 河盛隆造
- Organizer
  第52回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] Diabetes and Exercise : Intramycellular Lipid Accumulation and Insulin Sensitivity.2009
- Author(s)
  Tamura Y, Sakurai Y, Takeno K, Kakehi S, Ikeda S, Sato F, Hirose T, Watada H, Kawamori R.
- Organizer
  In The 15thKorea-Japan Symposium on Diabetes Mellitus Jeju p.84-85
- Place of Presentation
  Korea
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] Effects of high fat diet on intramyoellular lipid and insulin resistance.2009
- Author(s)
  Tamura Y, Sakurai Y, Takeno K, Kumashiro N, Ikeda S, Kakehi S, Watada H, Kawamori R
- Organizer
  14^<th> International Congress of Endocrinology
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] ヒトにおける高脂肪食負荷が、骨格筋細胞内脂質蓄積とインスリン抵抗性発生に与える影響とその規定因子2009
- Author(s)
  田村好史、櫻井裕子、筧佐織、池田真一、佐賀典生、小倉裕司、内藤久士、綿田裕孝、河盛隆造
- Organizer
  第64回日本体力医学会
- Data Source
  KAKENHI-PROJECT-21700548
[Presentation] 療養病床における施設運営と勤務医師の現状について2008
- Author(s)
  筧佐織, 高橋龍太郎
- Organizer
  第50回日本老年社会科学会大会
- Place of Presentation
  大阪堺
- Data Source
  KAKENHI-PROJECT-19700531
[Presentation] 療養病床における施設運営と勤務医師の現状について2008
- Author(s)
  筧佐織
- Organizer
  第50回日本老年社会科学会大会
- Place of Presentation
  大阪・堺
- Data Source
  KAKENHI-PROJECT-19700531
[Presentation] Physical inactivity and high fat diet synergistically enhance the accumulation of intramyocellular diacylglycerol and induce insulin resistance in murine soleus muscle.
- Author(s)
  Kakehi S, Tamura Y, Ikeda S, Kawamori R,Watada H
- Organizer
  50th EASD Annual Meeting
- Place of Presentation
  Vienna, Austria
- Year and Date
  2014-09-15 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] Physical inactivity and high fat diet synergistically enhance the accumulation of intramyocellular diacylglycerol and induce insulin resistance in murine soleus muscle.
- Author(s)
  Kakehi S, Tamura Y, Ikeda S, Kawamori R,Watada H
- Organizer
  50th EASD Annual Meeting
- Place of Presentation
  Vienna, Austria
- Year and Date
  2014-09-15 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] 高脂肪食負荷による骨格筋細胞内脂質蓄積は骨格筋中の脂質代謝関連遺伝子発現と関連する
- Author(s)
  筧　佐織、田村　好史、池田　真一、河盛　隆造、綿田　裕孝
- Organizer
  第35回　日本肥満学会
- Place of Presentation
  宮崎
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] Accumulation of intramyocellular lipid after high-fat diet is associated with the expression of genes involved in lipid metabolism in non-obese men
- Author(s)
  Kakehi S, Tamura Y, TakenoK, Sakurai Y, Kawaguchi M, Watanabe T, Funayama T, Sato F, Ikeda S, Kanazawa A, Fujitani Y, Kawamori R, and Watada H
- Organizer
  3rd international conference on Recent Advances and Controversies in Measuring Energy Metabolism
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2014-10-10 – 2014-10-12
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] 高脂肪食負荷による骨格筋細胞内脂質蓄積は骨格筋中の脂質代謝関連遺伝子発現と関連する
- Author(s)
  筧　佐織、田村　好史、池田　真一、河盛　隆造、綿田　裕孝
- Organizer
  第35回　日本肥満学会
- Place of Presentation
  宮崎
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] 不活動による骨格筋インスリン抵抗性惹起における脂質代謝酵素活性変化を介した骨格筋細胞内脂質の関与
- Author(s)
  筧　佐織、田村　好史、池田　真一、河盛　隆造、綿田　裕孝
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] Accumulation of intramyocellular lipid after high-fat diet is associated with the expression of genes involved in lipid metabolism in non-obese men
- Author(s)
  Kakehi S, Tamura Y, TakenoK, Sakurai Y, Kawaguchi M, Watanabe T, Funayama T, Sato F, Ikeda S, Kanazawa A, Fujitani Y, Kawamori R, and Watada H
- Organizer
  3rd international conference on Recent Advances and Controversies in Measuring Energy Metabolism
- Place of Presentation
  Tokyo
- Year and Date
  2014-10-10 – 2014-10-12
- Data Source
  KAKENHI-PROJECT-24500867
[Presentation] 不活動による骨格筋インスリン抵抗性惹起における脂質代謝酵素活性変化を介した骨格筋細胞内脂質の関与
- Author(s)
  筧　佐織、田村　好史、池田　真一、河盛　隆造、綿田　裕孝
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25350899
[Presentation] １週間のアルコール制限は肝臓特異的にインスリン感受性を改善し空腹時血糖値を低下させる
- Author(s)
  船山　崇,　田村好史,　竹野景海,　渡邉隆宏,　川口美奈子,　山本理沙子,　筧佐織,　藤谷与士夫,　河盛隆造,　綿田裕孝
- Organizer
  第57回　日本糖尿学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24300236
[]

1. TAMURA Yoshifumi (80420834)

# of Collaborated Projects: 8 results

# of Collaborated Products: 43 results
2. SAKURABA Keisyoku (50175460)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KAWAMORI Ryuzo (00116021)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. 加賀英義 (90814757)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 竹野景海 (50459062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 田端宏樹 (50876886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 小西清貴 (90323609)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 三浦芳樹 (90279240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SATOH Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. TAKA Hikari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. KAGA Naoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 上野紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 村山尚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 江島弘晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 門脇聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 柿木亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kakehi Saori 筧 佐織

KAKEHI Saori 筧 佐織

Research Projects

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Co-Researchers

Lipin1を中心とした骨格筋の質と量に与える影響における共通病態基盤の解明Principal Investigator

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Comprehensive study on skeletal muscle disorders caused by high-fat diet inactivity with a focus on the key molecule Lipin1.Principal Investigator

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Twenty-four hours physical inactivity induce insulin resistance in the muscle.Principal Investigator

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Elucidation of the molecular mechanism of muscle insulin resistance induced by physical inactivity and establishment of prevention method.Principal Investigator

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Mechanisms of insulin resistance after 24 hours physical inactivity in murine soleus muscle.Principal Investigator

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Clarification of molecular mechanism in prevention of muscular atrophy by transient blood flow restriction.Principal Investigator

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Kakehi Saori 筧佐織

KAKEHI Saori 筧佐織